Excerpt: Darwinism and Design – Discovery Institute

Editors note: We are delighted to celebrate the publication of the new book A Mousetrap for Darwin: Michael J. Behe Answers His Critics. What follows is an excerpt. Darwinism and Design was published originally as a letter to the editor in Trends in Ecology and Evolution 12, No. 6 (June 1997): 229.

Authors note: One of the earliest reviews of my book Darwins Black Box was by Oxford evolutionary biologist Tom Cavalier-Smith. I had discussed some of his musings rather unfavorably in the book, and he returned the favor in the review.

In his review of my book Darwins Black Box, which is critical of Darwinian theory, Tom Cavalier-Smith alternates between calling me ignorant and calling me deceitful, but finally seems to conclude that I am intentionally dishonest because of my religious views. I do not wish to descend into acrimony, so let me state plainly that my religious convictions can easily accommodate a Darwinian explanation for life, and I said so in my book. I have no motive, religious or otherwise, to be dishonest. I wrote the book (which I knew would be controversial) out of a straightforward, professional conviction that many complex biochemical systems are beyond Darwinian explanation.

Well, I am not dishonest, but am I ignorant? Perhaps so. No one can be completely in command of the literature, and I would be very happy to be shown citations to published work explaining in detail how complex biochemical systems evolved by natural selection. However, Professor Cavalier-Smith says there is no such work: For none of the cases mentioned by Behe is there yet a comprehensive and detailed explanation of the probable steps in the evolution of the observed complexity. The problems have indeed been sorely neglected. Yet he thinks that, even if detailed explanations are unavailable, general explanations are in hand. He cites ten references in his review. Of the ten, half refer to his own work, only four are published in this decade, and only two are reports of original research. From my point of view, in all of the cited papers the evolutionary explanation takes the form System X developed because it would help the cell to do Y, without noticing the difficulties of making X by a blind process. Its like saying, Air conditioners developed to enable more people to work indoors in the summertime.

Much of the difficulty arises in the differing standards that different disciplines have for what constitutes an explanation. Biochemists require molecular detail. Cavalier-Smith, however, does not. (Indeed, he even castigates Trends in Biochemical Sciences for noticing engineering design in biochemical systems.) Darwinian evolution, though, would necessarily have to take place at the nut-and-bolt molecular level, the domain of biochemistry. A Darwinian evolutionary explanation, therefore, has to be a detailed biochemical explanation. None currently exist. By itself this fact doesnt justify the conclusion of intelligent design that I reach. (I also advance other arguments for design in my book.) But by itself the absence of detailed Darwinian explanations should provoke more thoughtfulness than was shown in Cavalier-Smiths review.

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Excerpt: Darwinism and Design - Discovery Institute

Chemistry Seminar on ‘Calixpyrrole Ligands for Renewable Energy Applications’ Dec. 7 – University of Arkansas Newswire

photo submitted

Peter Sues

Peter Sues of Kansas State University will give a virtual seminar titled "Leveraging the Power of Multiple Metal Centers via Calixpyrrole Ligands for Renewable Energy Applications"on Zoomfrom 3:30-4:30p.m. Central on Monday, Dec. 7. The talk is free and open to the public.

Peter Sues joined the chemistry department at Kansas State University in August 2017. A native Torontonian, he received an Honours Bachelor of Science at the University of Toronto while majoring in chemistry and biochemistry. As an undergraduate student, he worked in the laboratory of Prof. Douglas W. Stephan exploring the chemistry of Frustrated Lewis Pairs.

He continued his education at the University of Toronto earning a doctorate under the mentorship of Prof. Robert H. Morris. His Ph.D. research focused on a variety of projects including the development of iron-based hydrogenation catalysts and the chemistry of ruthenium complexes with highly strained phosphine ligands.

Peter subsequently joined the laboratory of Prof. Richard R. Schrock at the Massachusetts Institute of Technology as a postdoctoral research associate. There, he expanded his chemical knowledge while working on tungsten- and molybdenum-based olefin metathesis catalysts.

Using his skills as an inorganic and organometallic chemist, he currently studies the development of novel catalytic systems for renewable energy applications and olefin metathesis that make use of sustainable resources.

Stockpiling the energy harvested from intermittent renewable sources in chemical bonds is an integral part of creating a sustainable energy economy. Abundant small molecules, such as N2, O2, CO2, H2O, etc., will play a pivotal role in this area as their reduction and oxidation will be key in generating power on an as-needed basis. Activating these substrates, however, is a kinetically challenging endeavour that requires multi-electron and multi-proton processes. Very few homogeneous catalysts are capable of effecting these transformations, and those that can largely rely on rare and expensive platinum group metals.

Natural systems, on the other hand, can activate small molecules efficiently using base metals. This is achieved through the use of multiple metal centers working in concert. Additionally, metalloenzymes are adept at controlling the orientation of small molecule binding and at protecting reactive intermediates by providing a sheltered active site for chemical transformations. Using natural systems as inspiration, the Sues groupenvisions utilizing multiple metal centers to activate small molecules through cooperative, multi-electron mechanisms. To do this, new ligand architectures are needed.

The Sues group uses calixpyrroles as they are synthetically facile and share some of the same characteristics as metalloenzymes: they can optimize the orientation of small molecule binding and increase catalyst stability by sheltering reactive intermediates in a supramolecular "catalytic cleft". This presentation will explore the synthesis of new calixpyrrole ligands and metal complexes.

To attend the seminar,please visit the Zoom link.Meeting ID: 858 0124 6081Passcode: Fall@2020

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Chemistry Seminar on 'Calixpyrrole Ligands for Renewable Energy Applications' Dec. 7 - University of Arkansas Newswire

Automated Biochemistry Analyzers Industry Research Report, Growth Trends and Competitive Analysis 2020-2027: Abbott, Danaher, Hitachi, Roche, Siemens,…

This report studies theAutomated Biochemistry Analyzersmarketwith many aspects of the industry like the market size, market status, market trends and forecast, the report also provides brief information of the competitors and the specific growth opportunities with key market drivers. Find the complete Automated Biochemistry Analyzers market analysis segmented by companies, region, type and applications in the report.

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Automated Biochemistry AnalyzersMarket continues to evolve and expand in terms of the number of companies, products, and applications that illustrates the growth perspectives. The report also covers the list of Product range and Applications with SWOT analysis, CAGR value, further adding the essential business analytics. Automated Biochemistry Analyzers Market research analysis identifies the latest trends and primary factors responsible for market growth enabling the Organizations to flourish with much exposure to the markets.

This report focuses on the globalAutomated Biochemistry Analyzersstatus, future forecast, growth opportunity, key market and key players. The study objectives are to present the Automated Biochemistry Analyzers development inUnited States, Europe, China, Japan, Southeast Asia, India, and Central & South America.

Market segment by Type, the product can be split into

Market segment by Application, split into

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TheAutomated Biochemistry Analyzersmarket research report completely covers the vital statistics of the capacity, production, value, cost/profit, supply/demand import/export, further divided by company and country, and by application/type for best possible updated data representation in the figures, tables, pie chart, and graphs. These data representations provide predictive data regarding the future estimations for convincing market growth. The detailed and comprehensive knowledge about our publishers makes us out of the box in case of market analysis.

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Chapter 1:GlobalAutomated Biochemistry AnalyzersMarket Overview

Chapter 2:Automated Biochemistry Analyzers Market Data Analysis

Chapter 3:Automated Biochemistry Analyzers Technical Data Analysis

Chapter 4:Automated Biochemistry Analyzers Government Policy and News

Chapter 5:Global Automated Biochemistry Analyzers Market Manufacturing Process and Cost Structure

Chapter 6:Automated Biochemistry Analyzers Productions Supply Sales Demand Market Status and Forecast

Chapter 7:Automated Biochemistry Analyzers Key Manufacturers

Chapter 8:Up and Down Stream Industry Analysis

Chapter 9:Marketing Strategy -Automated Biochemistry Analyzers Analysis

Chapter 10:Automated Biochemistry Analyzers Development Trend Analysis

Chapter 11:Global Automated Biochemistry Analyzers Market New Project Investment Feasibility Analysis

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Automated Biochemistry Analyzers Industry Research Report, Growth Trends and Competitive Analysis 2020-2027: Abbott, Danaher, Hitachi, Roche, Siemens,...

Biochemistry Analysers Market Thriving Growth during Forecast 2020-2028 with Leading Players Vetter Pharma, Ypsomed, SCHOTT, Nipro, Lyophilization…

Biochemistry Analyser is a medical device that uses the pale yellow supernatant portion (serum) of a centrifuged blood sample or a urine sample and contains reactions using reagents to measure various components, such as sugar, cholesterol, protein, enzyme, etc.

Due to the pandemic, we have included a special section on the Impact of COVID 19 on the Biochemistry Analysers Market which would mention How the Covid-19 is affecting the Biochemistry Analysers Industry, Market Trends and Potential Opportunities in the COVID-19 Landscape, Covid-19 Impact on Key Regions and Proposal for Biochemistry Analysers Players to Combat Covid-19 Impact

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The Biochemistry Analysers Market report covers all the elements and offerings quantitative and qualitative statistics about its basics on a global as well as provincial level. It offers a comprehensive overview of the global market along with the market influencing factors. Furthermore, it offers an in-depth description of the global market with respect to the dynamics of the market such as internal and external driving forces, restraining factors, risks, challenges, threats, and opportunities.

In addition, the report is wide-ranging of information on key pillars such as propellers and restraints which also help to understand the changeable trends of industries. The report further also underlines highlights recent trends, tools, and technology platforms that are facilitating to upsurge the performance of the companies.

The Top Key players of Biochemistry Analysers Market:

URIT Medical Electronic, ELITechGroup, Danaher, EKF Diagnostics, Roche Diagnostics, Spinreact, Mindray

The Biochemistry Analysers Market segmentation by Type:

The Biochemistry Analysers Market segmentation by Application:

The Biochemistry Analysers Market segmentation by Region:

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It also offers a comparative study of the Biochemistry Analysers Market to recognize the difference in performance among global competitors. Also, it represents how those competitors competing against each others to drive the trades rapidly. Researchers present enlightening information in a flawless and professional manner. Historical growth rate, as well as forecasted rate, is also mentioned in the report.

Table of Contents:

Chapter 1. Biochemistry Analysers Market Overview

Chapter 2. Market Competition by Players / Suppliers

Chapter 3. Sales and Revenue by Regions

Chapter 4. Sales and Revenue by Type

Chapter 5. Biochemistry Analysers Market Sales and revenue by Application

Chapter 6. Market Players profiles and sales data

Chapter 7. Manufacturing Cost Analysis

Chapter 8. Industrial Chain, Sourcing Strategy and Down Stream Buyers

Chapter 9. Market Strategy Analysis, Distributors/Traders

Chapter 10. Biochemistry Analysers Market effective factors Analysis

Chapter 11. Market Size and Forecast

Chapter12. Conclusion

Chapter13. Appendix

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Biochemistry Analysers Market Thriving Growth during Forecast 2020-2028 with Leading Players Vetter Pharma, Ypsomed, SCHOTT, Nipro, Lyophilization...

Itaconic Acid Market Growing Technology Opportunities and Future Business Trends to 2030 Qingdao Kehai Biochemistry Co LTD, Itaconix Corporation -…

Itaconic acid is also known as methylidenesuccinic acid and is an organic compound. It is a while solid that is able to dissolve in acetone, ethanol, and water. Initially, itaconic acid could be only obtained from the distillation process of citric acid, but presently, it can be obtained from the fermentation process. Methylidenesuccinic acid or itaconic acid is the more popularly understood as a precursor, especially for the synthesis of polymer and is importantly included in the several industrial processes for decades together. The latest surprising discovery found out that the said acid can potentially play a crucial role as immune-supportive metabolite in the mammalian immune cells, wherein it is synthesized from citric acid cycle (intermediatecis-aconitic acid) as antimicrobial compound.

The new report on Global Itaconic Acid Market presents all inclusive compilation of the historical, existing, and future trends to help business owners, strategy planners, marketing executives, and customers to plan effective strategies and gain prominent position in the near future. The report is also beneficial to the investors that will help them planning their future investments carefully and gain higher profits.

Market Breakdown:

The Global Itaconic Acid Market is categorized on the basis of product, application, end use, and region. Every segment is further sub-segmented with details on the leading segment and potential segment in the forthcoming years. Experts have accurately mentioned statistics associated with the vital report information like current demand, demographic details on key regions, import and export status, price preference, and consumer buying behavior.

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In-depth Segmentations of Itaconic Acid Market report :

Itaconic Acid Market by Key Players:

AEKYUNG PETROCHEMICAL Co., Ltd, Zhejiang Guoguang Biochemistry Co., Ltd., Qingdao Kehai Biochemistry Co., LTD., Itaconix Corporation, IWATA CHEMICAL CO., LTD., Chengdu Jinkai Biology Engineering Co., Ltd and Ronas Chemicals Ind. Co., Ltd, among others.

Itaconic Acid Market by Types:

Methyl MethacrylatePolyitaconic AcidStyrene Butadiene

Itaconic Acid Market by Applications:

Synthetic LatexChillant Dispersant AgentSBR LatexSuperabsorbent Polymers

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COVID-19 Impact on the Global Itaconic Acid Market:

The emergence of COVID-19 has created several disturbances in smooth functioning of businesses including production, delayed delivery of raw materials, reduced population in workspaces, supply chain interruptions, price fluctuations, and reduced demand from end users and customers. However, researchers have managed to study about the recent strategies during pandemic to avert huge losses and contribute stability of the Global Itaconic Acid Market. The report also mentions about the futuristic strategies and planning of the business owners post pandemic.

Regionally, the report described Global Itaconic Acid Market scenario in key regions including North America, Latin America, Europe, Asia Pacific, and Middle East and Africa. These regions are well-elaborated with highlights on main aspects to help businesses involved in the market to identify opportunities, increase their clients across the globe and expand their business geographically.

The report further states recently adopted growth strategies that contributed significant Global Itaconic Acid Market growth. Some of the common growth strategies implemented by the players in the Global Itaconic Acid Market include collaborations, merger and acquisition, new product development, innovations, and product campaigns. Report also encompasses company profiles, financial information, recent developments, latest news, and more.

What are the key Global Itaconic Acid Market drivers and restraints?

The key insights of the Global Itaconic Acid Market report:

Table of Contents:

Section 1 Report Overview

1.1 Study Scope

1.2 Key Market Segments

1.3 Regulatory Scenario by Region/Country

1.4 Market Investment Scenario Strategic

1.5 Market Analysis by Type

1.5.1 Global HR Core Administration Software Market Share by Type

1.6. Global HR Core Administration Software Market Share by Application

1.7 Global Itaconic Acid Market Development Trends under COVID-19 Outbreak

1.7.1 Global COVID-19 Status Overview

1.7.2 Influence of COVID-19 Outbreak on Global Itaconic Acid Market Development

Section 2 Global Market Growth Trends

2.1 Industry Trends

2.1.1 SWOT Analysis

2.1.2 Porters Five Forces Analysis

2.2 Potential Market and Growth Potential Analysis

Section 3 Value Chain of Global Itaconic Acid Market

3.1 Value Chain Status

3.2 Itaconic Acid Market Manufacturing Cost Structure Analysis

3.2.1 Production Process Analysis

3.2.2 Manufacturing Cost Structure of HR Core Administration Software

3.2.3 Labor Cost of HR Core Administration Software

3.2.3.1 Labor Cost of Itaconic Acid Market Under COVID-19

3.3 Sales and Marketing Model Analysis

3.4 Downstream Major Customer Analysis (by Region)

3.5 Value Chain Status Under COVID-19

Section 4 Players Profiles

Section 5 Global Global Itaconic Acid Market Analysis by Regions

5.1 Global Itaconic Acid Market Sales, Revenue and Market Share by Regions

5.1.1 Global Itaconic Acid Market Sales by Regions

5.1.2 Global Itaconic Acid Market Revenue by Regions

5.2 North America Itaconic Acid Market Sales and Growth Rate

5.3 Europe Itaconic Acid Market Sales and Growth Rate

5.4 Asia-Pacific Itaconic Acid Market Sales and Growth Rate

5.5 Middle East and Africa Itaconic Acid Market Sales and Growth Rate

5.6 South America Itaconic Acid Market Sales and Growth Rate

Section 6 Global Global Itaconic Acid Market Segment by Types

6.1 Global Itaconic Acid Market Sales, Revenue and Market Share by Types

6.1.1 Global Itaconic Acid Market Sales and Market Share by Types

6.1.2 Global Itaconic Acid Market Revenue and Market Share by Types

Section 7 Global Global Itaconic Acid Market Segment by Applications

7.1 Global Itaconic Acid Market Sales, Revenue and Market Share by Applications

7.1.1 Global Itaconic Acid Market Sales and Market Share by Applications

7.1.2 Global Itaconic Acid Market Revenue and Market Share by Applications

Section 8 Global Itaconic Acid Market Forecast by Regions

8.1 Global Itaconic Acid Market Sales, Revenue and Growth Rate

8.2 Global Itaconic Acid Market Forecast by Regions

8.2.1 North America Global Itaconic Acid Market Forecast

8.2.2 Europe Global Itaconic Acid Market Forecast

8.2.3 Asia-Pacific Global Itaconic Acid Market Forecast

8.2.4 Middle East and Africa Global Itaconic Acid Market Forecast

8.2.5 South America Global Itaconic Acid Market Forecast

8.3 Global Itaconic Acid Market Forecast by Types

8.4 Global Itaconic Acid Market Forecast by Applications

8.5 Global Itaconic Acid Market Forecast Under COVID-19

Section 9 Appendix

9.1 Framework

9.2 Study Data Source

9.2.1 Primary

9.2.2 Secondary

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Itaconic Acid Market Growing Technology Opportunities and Future Business Trends to 2030 Qingdao Kehai Biochemistry Co LTD, Itaconix Corporation -...

New AI That Predicts Shape of Proteins Could Solve 50-Year Problem – The Great Courses Daily News

By Jonny Lupsha, News Writer

According to The New York Times, a lab in London may have developed an artificial intelligence that can do a years-long task in less than a day, solving a longstanding problem of biology. For biologists, identifying the precise shape of a protein often requires months, years, or even decades of experimentation, the article said. It requires skill, intelligence, and more than a little elbow grease.

Now, an artificial intelligence lab in London has built a computer system that can do the job in a few hoursperhaps even a few minutes.

The article said that the laboratory in question, DeepMind, analyzes a string of amino acids that make up a protein and then rapidly and reliably predicts its shape. But why is that so important?

The study of folding proteins began in the 1950s with American biochemist Christian Anfinsen playing a key role.

The first experiments began by taking a protein out of the cell, unfolding it, and then seeing if it could refold in a test tube, independent of any cellular factors, said Dr. Kevin Ahern, Professor of Biochemistry and Biophysics at Oregon State University. The protein Christian Anfinsen picked was the enzyme ribonuclease A, also known as RNase, which turned out to be a serendipitous choice. RNase is relatively small as proteins goabout 100 amino acidsand it is also extraordinarily stable.

Dr. Ahern said that most enzymes are very sensitive to changes in temperature or pH balance, but RNase is not. Anfinsen showed that once an enzyme is unfolded, its capable of refolding outside the cell. His work earned him the 1972 Nobel Prize for Chemistry. Dr. Ahern also said that this process is called renaturation because the protein gets returned to its native or natural state.

Humanity has been studying protein folding for over 60 years. What happens when proteins fold incorrectly? As it turns out, nothing good.

These are the so-called prion diseases, also known as transmissible spongiform encephalopathies or TSEs, Dr. Ahern said. Prion diseases affect humans and other animals. They are a group of degenerative disorders that affect the brain, creating microscopic holes that make the tissue look like a sponge.

He also said that one of the best-known prion diseases is bovine spongiform encephalopathy, also known as Mad Cow Disease. Animals that had it would exhibit behaviors that were consistent with neurological damage, and finding a common cause among them was difficult.

Stanley Prusiner at the University of California at San Francisco ultimately identified the infectious agent as a proteina proteinaceous infectious article he called a prion, Dr. Ahern said. That a protein could be infectious by itself was unheard of at the time. And [it] turned out to be a cellular protein found on the membrane of healthy cells; though its function to this day remains uncertain.

Protein misfolding causes several serious diseases and helps explain why the study of protein folding matters so much.

This article was proofread and copyedited by Angela Shoemaker, Proofreader and Copy Editor for The Great Courses Daily.

Dr. Kevin Ahern contributed to this article. Dr. Ahern is a Professor of Biochemistry and Biophysics at Oregon State University (OSU), where he also received his PhD in Biochemistry and Biophysics.

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New AI That Predicts Shape of Proteins Could Solve 50-Year Problem - The Great Courses Daily News

Latest News:: Biochemical Diagnostic Reagent Market is expected to witness an exponential growth over forecast year 2020-2026| Roche, Siemens…

Chicago, United States: Global Biochemical Diagnostic Reagent Market Report offers an entire study of the Impact of COVID-19 on Biochemical Diagnostic Reagent Market, Industry Outlook, Opportunities in Market, and Expansion By 2026 and also taking into consideration key factors like drivers, challenges, recent trends, opportunities, advancements, and competitive landscape. This report offers a clear understanding of this also as a future scenario of the worldwide Biochemical Diagnostic Reagent industry. Research techniques like PESTLE and SWOT analysis are deployed by the researchers. They need also provided accurate data on Biochemical Diagnostic Reagent production, capacity, price, cost, margin, and revenue to help the players gain a clear understanding of the general existing and future market situation.

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Biochemical Diagnostic Reagent Market competition by top manufacturers/Key player Profiled:Roche, Siemens Healthineers, Beckman Coulter, Randox, BioSino, Beijing Leadman Biochemistry, FosunPharma, Beijing Strong Biotechnologies, Dojindo Laboratories, Sysmex, KAINOS Laboratories, DAAN Gene

The study objectives of Biochemical Diagnostic Reagent Market report are: 1.To identify opportunities and challenges for Global Biochemical Diagnostic Reagent .2.To provide insights about factors affecting market growth. To analyze the Biochemical Diagnostic Reagent market based on various factors- price analysis, supply chain analysis, SWOT analysis, etc.3.To identify and analyze the profile of leading players involved within the manufacturing of worldwide Biochemical Diagnostic Reagent .4.To provide country-level analysis of the market regarding the present Biochemical Diagnostic Reagent market size and future prospective.5.To examine competitive developments like expansions, new product launches, mergers & acquisitions, etc., in Global Biochemical Diagnostic Reagent .6.To provide a detailed analysis of the market structure alongside forecast of the varied segments and sub-segments of the worldwide Biochemical Diagnostic Reagent market.

By Types, the Biochemical Diagnostic Reagent Market can be Splits into:

Liquid Double ReagentDry Powder Double Reagent

By Applications, the Biochemical Diagnostic Reagent Market can be Splits into:

HospitalClinicLaboratory

Global Biochemical Diagnostic Reagent Market is estimated to reach xxx million USD in 2020 and projected to grow at the CAGR of xx% during the 2021-2026. The report analyses the global Biochemical Diagnostic Reagent market, the market size and growth, as well as the major market participants.

The analysis includes market size, upstream situation, market segmentation, market segmentation, price & cost and industry environment. In addition, the report outlines the factors driving industry growth and the description of market channels.The report begins from overview of industrial chain structure, and describes the upstream. Besides, the report analyses market size and forecast in different geographies, type and end-use segment, in addition, the report introduces market competition overview among the

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Regions Covered in these Report:

Asia Pacific (China, Japan, India, and Rest of Asia Pacific)Europe (Germany, the UK, France, and Rest of Europe)North America (the US, Mexico, and Canada)Latin America (Brazil and Rest of Latin America)Middle East & Africa (GCC Countries and Rest of Middle East & Africa)

Global Biochemical Diagnostic Reagent Market is highly fragmented and the major players have used various strategies such as new product launches, expansions, agreements, joint ventures, partnerships, acquisitions, and others to increase their footprints in this market. The report includes market shares of Biochemical Diagnostic Reagent Market for Global, Europe, North America, Asia-Pacific, South America and Middle East & Africa.

Reasons To Buy: Make strategic business decisions using in-depth historic and forecast market data associated with the Biochemical Diagnostic Reagent market, and every category within it.Extensive price charts draw particular pricing trends within recent yearsPosition yourself to realize the most advantage of the Biochemical Diagnostic Reagent markets growth potentialTo understand the latest trends of the Biochemical Diagnostic Reagent marketTo understand the impactful developments of key players within the market, their strategic initiatives and comprehensively study their core competencies

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Table of Contents

Report Overview:It includes major players of the global Biochemical Diagnostic Reagent Market covered in the research study, research scope, and Market segments by type, market segments by application, years considered for the research study, and objectives of the report.

Global Growth Trends:This section focuses on industry trends where market drivers and top market trends are shed light upon. It also provides growth rates of key producers operating in the global Biochemical Diagnostic Reagent Market. Furthermore, it offers production and capacity analysis where marketing pricing trends, capacity, production, and production value of the global Biochemical Diagnostic Reagent Market are discussed.

Market Share by Manufacturers:Here, the report provides details about revenue by manufacturers, production and capacity by manufacturers, price by manufacturers, expansion plans, mergers and acquisitions, and products, market entry dates, distribution, and market areas of key manufacturers.

Market Size by Type:This section concentrates on product type segments where production value market share, price, and production market share by product type are discussed.

Market Size by Application:Besides an overview of the global Biochemical Diagnostic Reagent Market by application, it gives a study on the consumption in the global Biochemical Diagnostic Reagent Market by application.

Production by Region:Here, the production value growth rate, production growth rate, import and export, and key players of each regional market are provided.

Consumption by Region:This section provides information on the consumption in each regional market studied in the report. The consumption is discussed on the basis of country, application, and product type.

Company Profiles:Almost all leading players of the global Biochemical Diagnostic Reagent Market are profiled in this section. The analysts have provided information about their recent developments in the global Biochemical Diagnostic Reagent Market, products, revenue, production, business, and company.

Market Forecast by Production:The production and production value forecasts included in this section are for the global Biochemical Diagnostic Reagent Market as well as for key regional markets.

Market Forecast by Consumption:The consumption and consumption value forecasts included in this section are for the global Biochemical Diagnostic Reagent Market as well as for key regional markets.

Value Chain and Sales Analysis:It deeply analyzes customers, distributors, sales channels, and value chain of the global Biochemical Diagnostic Reagent Market.

Key Findings: This section gives a quick look at important findings of the research study.

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Latest News:: Biochemical Diagnostic Reagent Market is expected to witness an exponential growth over forecast year 2020-2026| Roche, Siemens...

Why America’s leaders need to improve communication now in the COVID-19 crisis – KARE11.com

Dr. Matthew Seeger co-wrote the CDC's crisis communications manual, but says America's leaders didn't follow it at the start of the pandemic.

There is a playbook in America for how leaders should communicate with citizens in a crisis: that could be a hurricane, a terror attack, or even a pandemic.

Dr. Matthew Seeger of Wayne State University knows all about that playbook, as he was one of the experts who contributed to writing the CDC's 450-page manual for how U.S. leaders should communicate during a health crisis

"I've worked my entire career in the field of disasters and crises. I've worked for CDC and WHO," Dr. Seeger said. "I helped the CDC develop some of their crisis communication plans."

Sadly, he says, Americas leaders did not follow this playbook back in the early part of 2020, but that they should get back to it now as we approach an uncertain winter and COVID-19.

"Pretty much every public health official in the country was trained in crisis and emergency risk communication using the CDC materials. Sadly, we did not follow that protocol with the COVID 19 pandemic," he said.

While we can argue about why that was, we cannot change what was. The missed chance of having a consistent and clear message to all Americans, is missed; but, we are still in crisis, so Dr. Seeger says it's time to communicate still, and aim to be consistent in messaging

"The principal way in which we manage COVID 19 is through human behavior," Seeger said. "That requires that we inform and we persuade people using communication, messaging to get them to change their behavior."

And right now is more important than ever, as whatever officials said in their plea to get folks to stay home for Thanksgiving -- didn't work for millions of Americans.

With another major holiday approaching, Dr. Seeger says we have to try again, but leave shaming and yelling at people, at the door. That doesn't work.

"It actually may persuade people to continue those problematic behaviors because they may feel that they are being attacked; and they really need to double down on their behaviors because then it becomes us vs. them," he said.

So what should leaders do? Dr. Seeger says, tell the human story of COVID, and tell ALL of them.

"Personalize this to say these are your friends, this is your family, your children, your brothers your sister. It's harder to demonize individuals when we recognize these people are part of our lives," he said. "I also think it's important we tell the story of the individual who was skeptical and try to allow them a space to express themselves rather than demonize that attitude."

Think of it like your social media feed when it comes to ads, the ones that work that target your lived experience. So far, with mixed messages, confusing messages, misinformation and mandates, it's left too much room.

So has, in his opinion, only one message for everyone.

"One of the challenges with some of our messaging is one size fits all," Dr. Seeger said. "We tell people to wear masks and stay away from others. If I live in a multigenerational household or I have to go to work, it's much more difficult for me to comply with some of those recommendations, so we need to be more sensitive and nuanced in what we are saying to people and how we are saying that to people."

Continue reading here:
Why America's leaders need to improve communication now in the COVID-19 crisis - KARE11.com

Is It a Boy or a Girl? – Discovery Institute

Photo credit: Christian Bowen via Unsplash.

Authors note: This is Part One of a seven-part series about transgenderism. Nothing in the series is intended to disparage any transgender person, any gender non-conforming person, or any person attracted to members of the same sex. I write as a developmental biologist (Berkeley PhD), and I focus on evidence pertaining to transgender treatments for children.

WARNING: Parts of this series contain explicit language. Reader discretion is advised.

Parents with a new baby are almost always asked, Is it a boy or a girl? And the answer is almost always one or the other.

About 99.98 percent of babies are clearly boys or girls. Only about one baby out of every 4,500 has ambiguous genitals. The cause is a disorder of sexual development (DSD). The term DSD is now often replaced by intersex.

In 2000, biologist Anne Fausto-Sterling argued that intersex births occur about 1.7 percent of the time instead of 0.02 percent. But physician Leonard Sax objected that Fausto-Sterling defined intersex too broadly. On the contrary, he maintains, human sex is about 99.98% binary.

Humans normally have 46 chromosomes. Two of these are the sex chromosomes, X and Y. Almost all babies with 46 chromosomes and two X chromosomes (designated 46,XX) are clearly girls. And almost all babies with 46 chromosomes and a Y as well as an X (designated 46,XY) are clearly boys. But (as with many things in biology) there are exceptions.

About one in 20,000 boys is born with 46,XX chromosomes. In most, the male-determining section of the Y chromosome has become attached to an X chromosome. Fewer than one in 20,000 girls is born with 46,XY chromosomes. Probably, mutations have blocked male development.

Some people have argued that the brains of male and females are different. Others disagree and argue that there is no such thing as a male brain or a female brain. So far, neuroscience has not settled the disagreement.

Some people have argued that sex is binary because of the gametes (the sperm and the egg). In 1949, feminist author Simone de Beauvoir wrote (p. 47) that male and female are basically defined by the gametes they produce. In 2018, biologist Jerry Coyne echoed this: If you adhere to the gamete-based definition used by most biologists, sex is effectively binary. Furthermore, Coyne argued, it should be, since evolution produced (in most animals) two sexes that must mate to produce offspring. If youre neither, or an intermediate, you dont leave offspring and you dont leave your genes.

In 2020, biologists Colin Wright and Emma Hilton wrote in The Dangerous Denial of Sex that sex is sometimes ambiguous. But intersex individuals are extremely rare, and they are neither a third sex nor proof that sex is a spectrum or a social construct:

In humans, reproductive anatomy is unambiguously male or female at birth more than 99.98% of the time. The evolutionary function of these two anatomies is to aid in reproduction via the fusion of sperm and ova [eggs]. No third type of sex cell exists in humans, and therefore there is no sex spectrum or additional sexes beyond male and female. Sexis binary.

This does not mean that the behavior of males and females is strictly binary. Men and women exhibit a range of masculine or feminine behaviors. And sexual attraction is not binary. Most men and women are exclusively attracted to members of the other sex. Some are exclusively attracted to members of the same sex. And some are in between. So human behavior, unlike biological sex, is bimodal rather than binary. That is, it has two overlapping humps instead of two separated sharp peaks.

A graph of biological sex would look like the upper part of a football goal post. The goal post is a raised horizontal bar topped by two vertical posts 8 feet apart and 20 feet high. One vertical post represents boys, and the other represents girls.

Because some people are intersex, the top surface of the horizontal bar would not be exactly flat. Instead, it would be the thickness of a credit card higher at either end than in the center. But this would be unnoticeable to someone standing just a few yards away.

Note that the football goal post metaphor is descriptive, not prescriptive. It does not mean that intersex people must conform to one of the uprights.

Parents of newborn intersex babies may feel they should make their children more normal. Yet there is rarely a medical need for such intervention. Some intersex babies suffer from life-threatening conditions that require immediate hormonal or surgical treatment. But apart from such special cases, babies born with ambiguous genitals can grow up without medical intervention to live relatively normal lives.

As philosopher Ellen Feder and historian Alice Dreger wrote in 2016:

Children with DSD can be raised as boys and as girls without being subjected to elective surgeries that lack evidence for necessity, safety, and efficacy, and more importantly that violate their rights [There is a] difference between atypical and unhealthy.

In 2017, three former U.S. surgeons general published a report titled Re-Thinking Genital Surgeries on Intersex Infants. They noted that before the middle of the twentieth century, most children born with genitalia that did not fit the male-female binary norm were not subjected to surgery. Beginning in the 1950s, however, the standard treatment protocol shifted to favor surgery.

Fifty years later, medical opinion is shifting back, for three reasons. First, evidence is lacking that such surgeries make intersex people happier. Second, evidence does show that the surgery itself can cause severe and irreversible physical harm and emotional distress. Third, when such surgeries are performed on children they violate an individuals right to personal autonomy over their own future.

Why did the standard protocol shift to favor surgery in the 1950s? One person stands out: John Money. Moneys ideas and their tragic results are the focus of Parts Two and Three of this series.

Originally posted here:
Is It a Boy or a Girl? - Discovery Institute

Rich Roll On How to Evolve, Reach Your Goals: Take the First Step – The Beet

The prospect of getting on the phone with Rich Roll is intimidating. What could I possibly ask him to solicit insights that his 11 million listeners (who have downloaded hispodcasts 26 million times) have not already heard, our soaked up, or leaned from the modern master of self-help, self-realization and self-reflection?

Rich Roll has already told the world about his squandering a talented swimming career that got him recruited to every Ivy League college, and aplace on therevered Stanford team, where hediscovered a love of drinkingand hatred for 200-meter repeats. He finally quit out of a lack of commitment, and it was the beginning of a relationship with alcohol that nearly destroyed him.

Roll has also shared his painful journey into addiction, ill health, lethargy and finallybouncing off the floor, enteringrehab and starting along the road to recovery. And he has told the story of rebuilding his life, rock by rock, step by step, and finding a new passionfor running, eating healthy, and eventually going vegan. During his rehabilitation, he lost 40 pounds and rediscovered a love of competitive long-form endurance sport: Swimming, running, biking and eventually competing in the longest and most grueling endurance races on the planet. Ten years ago, Roll competed in the Epic5, the unfathomable series of 5 Ironman races in five days on five Hawaiian islands. It'sthe kind of thing you read about in fiction books when the hero has to cross land and sea to save his civilization. Only this insane event is entered by choice. The distancesgrinding out 2.4 miles in the water, then 112 on the bike against sheering headwinds, and then running 26.2on punishing volcanic terrain, and doing it all overagain the next day,fivedays in a rowbend the arc of reason. No human should be able to do this, much less enjoydoing it, just for kicks.

So I am getting on the phone with this epic athlete who while spending all those hours in motion also spent mental time examining his life, thinking and writing his story, which led him to start his podcast, interviewing athletes and actors, gurus and other seekers, and in the process learning more about humanity to the point where he switches from being the student of human behavior to teaching recovery and redemption to anyone who listens. So that inner process of evolving is ultimately what Roll is known for, even more than the physical feats.

The excuse for the interview is his new book, Voicing Change, a compendium of his conversations with others over a microphone, but even though I am not one of his mostdevoted listeners, I know that Rich Roll has things to teach me, all of us, and I was eager to learn. You dont go into an interview with Roll lightly or ask him for "5 tips forkeeping your dieton track." Expectations for enlightenment are high: You ask him the deep, lingering questions that come to you on a long run or ride, the kinds of things best-selling books are written about. Like his first book, Finding Ultra, which I have read.

I knew my first question, which was both personal and universal, and it had been gnawing at me for months, all during quarantine when time appeared to stand still, but in fact, the days wereticking by and the earth was turning as fast as ever, and I knew this because the moon came up over the eastern horizon every night and set in the west, moving across thebay sky as I would lie in bed, unable to sleep.

Here is my question: How can we evolve, as humans? What is our best chance atbecominga better person, forgiving ourselves the stupid, regrettable acts of the day, and starting fresh tomorrow, and try not to make the same mistakes over and over again? How can we get it right? I feel like I've dropped off a cliff, training-wise, eating-wise, and though I'm plant-based, I regularly choose sweets over salads and let myself off the hook too easily. I have completed 3 Ironman races, trained for 4 (dropping out 3/4 of the way through due to a tendon tear in my left ankle). But even writing that last sentence makes me cringe since I am barely fit enough to run4 miles. I miss beinglight and on my game.

I dont expect that everyone can relate to being determined enough to finish running an Ironman race on a broken foot, which I did once, but perhapseveryone can relate to self-destructive behavior, and Rich talks about that too and how to deal with our patterns, whether they be compulsive shopping or drinking or sugar-binging. He relates personal behavior to emotional and spiritual behavior. Everyone can relate towanting to be a better person, friend, spouse, parent, or daughter. Or just finding joy. (Most of us have an endless to-do list that nags at us when we should be enjoying ourselves at a family night of games or movie watching.) Roll explains how he has gained an acceptance of his extreme "all in" personality and how we can find our own authentic selves and play to our strengths.

In short, I wanted to know from Rich, how do you keep evolving, to be more community-minded, planet minded, get out of your own way and jettison self-destructive patterns,to be a better person? If, as Roll writes in his first book, Finding Ultra, we are all sitting on a mountain of untapped potential, how do we reach that potential, physically, emotionally and spiritually? If we have a song to sing, how do we have the courage to sing it?

No surprise, he gave me a lot to think about. He always gives us all a lot to think about. Here is Rich Roll, on evolving, changing and coping with the fact that not everyone around you is on the same journey. His new book is a gorgeous coffee table-sized compilation of these conversations. Here is what we learned: You can evolve without pain and it can happen incrementally .... not just through dramatic and meaningful schisms. Here is our interview.

The Beet: Everyone I know is jealous of my being on this call. I have about six people who are all either Iron people orvegan or both, who would pay to trade places with me.

Do you think it only really happens when someonehas to change is forced to, because of a medical or other urgent health or psychological event? How can you get someone you love, who is not being healthy, to evolve (to go plant-based or quit smoking or change other self-destructive behavior) or do we need to be the ones to evolve, to a state of acceptance?

Rich Roll: You actually have two questions here. I think the first part of the question -- can one evolve without reaching a crisis point, is yes.It's certainly easier to change, when you find yourself in a pain point, whether it's physical, financial or existential. When you are up against it...your back is up against the wall like you find yourself in rehab or the cardiologist's office, then the choice is made for you. You can't see your way forward. Certainly, that was true for me. That's how I became sober and changed my relationship with food and drink.

When the fear of the unknown is outweighed by the fear of the present, it makes it much easier to change. These fears can be toggled and calibrated but here's the truth: Nobody gets out of life alive. We all face challenges and urgencies. The key is to recognize those moments when you can, because when you recognize that moment when change is needed, and channel it and take that momentum and turbocharge whatever change you are about to make, then you recognize that it has to happen to go forward.

The Beet: Why don't we change by choice? Can we change because we want to?

Rich Roll: Change is always available to us.We don't have to wait until something happens to take advantage of it. For whatever reason, as we get older we get calcified and it's harder to change. The podcast is my own exercise in holding me accountable for that.

Itdoes not need to be a big sweeping dramatic change. You don't need to go vegan overnight, you can do it gradually with small steps. We can decide to make tiny little micro-changes that we can make each day. It doesn't have to be these lines in the sand. Like going vegan. It can be small tweaks. You can decide to give up dairy and then expand from there.

Rich Roll: For most people change is a linear process, done incrementally. You really can take one step forward and two back. If you can make one small change and then hold yourself accountable to that, in the day-to-day, that seems imperceptible. One example is, "I am just going to put almond milk in my coffee and no one is going to notice that," but if you do that for a month, then you add more little decisions like that every day or week or month and over the course of a year or a decade, you are going to be a different person. It's not sexy or noticeable, but it's the grunt work you do (like getting up every morning and going for a run) to make yourself into a different person.

How do you change once things are going well? It's harder. Now, my life is really good. I am happy and I am not meeting those pain points and I have to make myself take these little iterations to move forward. That is where discipline comes in.

Rich Roll: If everything is going well you don't have to change, and people will tell you "Don't change!"But I always look at it from the perspective of a counselor in my treatment who said something I'll never forget, which is that most people fall under the delusion that their lives are essentially static. But that is a complete delusion because every behavior you make or conversation you have with another person is either moving you toward growth or away from it. For me, that means every decision I make is either moving me towards a drink or away from it. What is the next choice I am going to make, or movement I am going to take? And the more you root yourself at the moment and not focus on the long termthe more successful you will be. Think about the immediate next step. It's fine to have goals, and important to have long-term goals of the idealized version of what you want to be. But goals are temporal and once you achieve them it's easy to regress.

Rich Roll: But if you focus on what is the next right thing you need to do, and keep that long term goal in the back of your mind,just take the next step.Goals are there, in the background, but they should not be the first thing you think about. In training for an Ironman triathlon, you think, "I am going to have to get in the water." But don't worry about the 5,000 meters you have to swim today. Just jump in the pool. Then just take a stroke. Then just swim. Don't let the bigger goal overwhelm you. Just do the next right thing.

Reading your book I could relate to the idea of not always doing the right thing, and undermining myself. I am not saying I am addicted to sugar, but at times it feels like it! How do you stop doing things that are unhelpful, that undermine the goal? Like I want to save money and I go online and buy three sweaters. What do you say to this kind of self-undermining?

Rich Roll: Addiction lives on a spectrum and everyone can identify themselveson that spectrum, from the guy who can't pull the needle out of his arm, to the compulsive online shopper, to the person who ends up in a toxic relationship, or the person who eats the pint of ice cream... It is a sense ofnot being in control of what is soothing you in the moment. And we are unconscious to the extent that we medicate our emotions, from our relationship with food or shopping or alcohol or emotions. Anything can be classified as an addictive tendency.

Rich Roll: It is messy and complicated and all those things. There is something to be said for stepping outside your comfort zone and expanding your limits and yet at the same time you can use Ironman training to run away from things. We have all heard of the Ironman widow. It's about your motivation, You can use Ironman to validate yourself. But when you do that, you are really obfuscating and cutting corners, because you can be doing it just to get the pats on the back. What are people are going to say? When I am an Ironman? Ask yourself why do you need that and who are you trying to prove yourself to? Maybe you can get that validation another way.

The question is: Is there a place for balance in your life? Youre podcasting and writing, and training. How do you balance thesea passion for work and a dedication to training?

Rich Roll -- I hate that word balance. Can't stand it.It sets up this imaginary bar that we are all supposed to measure ourselves against. It implies these imaginary buckets that we are all supposed to fill up equally, and have all of these different things humming along at the right levels. There is no way my life is in balance. It's completely out of balance and I used to try to force myself to adhere to this imaginary equation. Then I had an epiphany and realized this is not who I am, and I started letting go of it. I need to live the way I'm wired.

I appreciated the fact that I have this motor that allows me togo all-in on something and now I no longer try to apologize for thator change how I function. Instead, I try to use that to my advantage. When I am doing something, like decorate the tree, I am all in on that. And I am completely focused on it, and then when that is over I switch gears. And when you look at my life on a day-to-day basis it seems out of balance, but then when you look at my year, you realize I am in balance.

I am cognizant of the fact that most people are not wired that way, and I am cognizant that I can't cross over and give advice since everyone is different and I can only tell you what works for me.

Rich Roll: Joy is tricky for me. That is kind of a final frontier. My wife is always saying to me: "You've done all these things and now can you just enjoy it?" I get satisfaction out of the grind and trying to do the best work that I can. I would not classify it as joy. The same is true with training. I don't want to just go out there and enjoy it. I need to go all out. Can I train for the joy of it, without some expectation that I will be better, or faster? As I get older I am trying to do that. As a recovering alcoholic, I am trying to be upbeat and not reclusive and work on all of these tendencies I have to overcome. I bump up against it. But especially amidst the chaos going into the next year.

Whose words do you remember most? Who sticks with you? Who have you learned the most from? Your relationship is a formative new conversation.

Rich Roll. You are asking me to choose between my babies. It's always fun to talk to aIt's fun Russell Brandor Matthew McConaughey. But the ones that are probably the most memorable to me and most meaningful are the interviews where someone who has an amazing story tells it and that story has not been widely told. When I am able to bring it to a new audience, that's meaningful. My favorite podcast is when I uncover somebody with an amazing story who is living anonymously and I get to be the one to say, "You guys have to hear this!"

Say there is someone I love and I would love for them to change and evolve? And maybe I wish they would go plant-based, but they reject every effort and tell me to stop pushing "that vegan stuff" on them. Maybeit's a sibling or a spouse or a parent. How do you deal with someone unwilling to try?

Rich Roll: So your attempts -how are they going?(Laughs.) Not well, right?

You are powerless when it comes to other people's behavior and life choices. So the more you develop an expectation around that, the more you suffer and will get hurt. When I was drinking, everyone wanted me to stop. You can lead someone to water but you can't make them drink. And in the context of relationships, it's important that you do an inventory for yourself around the dynamic. Everyone has their flaws, and you have to ask yourself if this person never changes, do I still love that person and want to be with this person?

As for changing someone else's behavior, you have to let it go. You can be a lighthouse and live by example. But let go of any expectation that it's going to slide downhill and make them change. It's none of your business. It's not up to you to judge someone else's way of living. The minute you drop the judgment, it changes the dynamic. It's healthier.

Rich Roll: I think that all the trends suggest that plant-based is continuing to explode.And more people are jumping on the bandwagon, and I don't see any ceiling. With the pandemic, you are seeing companies like Beyond Meat have take over the fast-food industry...You can get Beyond at Carls Junior and it's about to launch at McDonald's. But does that mean everyone is going to make the switch to plant-based? Maybe not, but the Gen Zs are so much more a-tuned to the planetary implications. For them, they have no qualms at all with switching to meatless food. It's not a big deal. They just think: this is better, visa vis the planet.

As for the health of these meat alternatives, I dohave concerns about the meat and dairy analogs. It has never been easier to be a junk food vegan. You can get vegan ice cream that is just as sugar-filled, and not goodfor you. I myself delude myself that I can eat coconut cream ice cream because it's healthier. So I would like to see more people taking up a whole-food, plant-based diet. But these items are a good way to understand you can eat what you want and give up meat and dairy.

RR: You have to meet people where they're at.Andthere is a contingent of the vegan community that gets ruffled by the fast-food options that are meatless but not vegan, I get it. But if people are eating this stuff as a way in, to becoming more plant-based or plant-focused, then I think it's worth it.

Rich Roll. Do I have a Mantra? I do, and it harkens back to that question of how can you evolve?

My Mantra is: Mood Follows Action.

Rich Roll: What that means is we have this human tendency to try to make a change, and then we wait to do the hard, uncomfortable thing. We wait until we feel like doing it. But that day never comes. But to me,Mood Follows Actionmeans the action precedes the mod. If you wait to take the actionwhen you feel like it you may never do it. That helps me take the first step,like jumping into the cold water when I may not feel like it, or not hitting snooze on the alarm. And that approach has helped me in many contexts. It has helped me since I first heard it back in AA many years ago. Does the mood follow? Well, yes. You never do the thing and think, "I wish I hadn't done that."

Excerpt from:
Rich Roll On How to Evolve, Reach Your Goals: Take the First Step - The Beet