Genetics

Genetic scientists map spread of Covid-19 in New Zealand – RNZ

Genetic scientists mapping the spread of Covid-19 say that as few as 35 cases may have led to the outbreak here.

A 3D model of the Covid-19 coronavirus. Photo: Supplied

ESR (Institute of Environmental Science and Research) has been analysing virus samples to try to build a comprehensive picture of how it has spread through the country - and how it has mutated along the way.

The scientists' ultimate goal is to genetically map every single case, which could provide invaluable insights in the fight against the disease.

New Zealand's first Covid-19 case was reported on 28 February - a person in their 60s who had arrived from Iran.

Just one month later, the entire country was in lockdown, with the borders shut tight and all but essential services forced to close.

ESR's head of bioinformatics, Joep de Ligt, said the genomic sequencing that has been carried out so far indicates the outbreak was generated by remarkably few cases.

"At the moment there's at least 35 unique introductions. They've come from all over the world, so we've seen them from Europe, from Iran, from North America," he said.

"This is consistent with what other countries have seen - it was these international travellers who have brought it in during that narrow window before the borders have closed."

The scientists look at Covid-19 samples and, due to tiny mutations that occur as the virus spreads, they are able to trace the chain of transmission and determine their origin.

"It's a bit like Where's Wally? Or Spot the Difference, where you have the picture from the original virus and you compare that [with the picture from new cases] and look for the difference."

Their ultimate goal is to analyse every single case here.

So far they have sequenced 125 samples from the 623 cases that have been sent to ESR.

Dr Jemma Geoghegan from the University of Otago's Department of Microbiology and Immunology has been analysing and interpreting the data.

She said the low number of infected people puts scientists in a good position to build a complete picture of the virus in this country.

"We're in a really unique position to be able to do that. It will provide us with a really amazing data set to help us understand how the virus spread here, what happened when we closed our borders, what happened when we went into level 4 lockdown, for example, and as we begin to lift those lockdown restrictions, what happens to transmission of the virus."

Infectious diseases expert Professor David Murdoch said understanding the genetics of the virus was a hugely helpful supplement to more traditional contact tracing, which could rely on assumptions and people's memories.

"Most of the information we get about identifying the source and how the transmission chain has occurred is through interviews and finding out what people have done and the contacts they've had," he said.

"That's obviously very useful but the genetic material as well gives a different and in many ways much finer detail about the specific strain that people have - where the transmission chain has come from, where the virus may have been imported from and who has had contact with who."

Scientists have obtained the DNA sequence from the first confirmed Covid-19 case and so far there is no evidence to suggest the virus was here before 28 February.

Read more about the Covid-19 coronavirus:

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Genetic scientists map spread of Covid-19 in New Zealand - RNZ

Genetics

How to find Genetic Heritage Instagram filter? Here is how to use the fun filter – Republic World – Republic World

People are spending their time in the coronavirus quarantine either by doing something at their homes or by sitting and exploring social media. There are many Instagram filters that are available on the app that people use in order to have fun and pass their time. These effects notonly entertain but also help in uplifting the moods of people.

(Source: Instagram Explore Page)

ALSO READ | What Is The Guess The Celebrity Instagram Filter? Read To Know More About This Fun Filter

One of the most recently trending Instagram filters that people are keenly enjoying is the one that tells you about your Genetic Heritage. The name of the filter is 'Genetics Scanner'. It is made by Instagram user @iamcraiglewis2.

The Genetic Heritage filter is a funny Instagram filter. When one applies the filter, their face is shown to be getting scanned from top to bottom. And then at the end, the person is said to be any kind of a funny reptile or animal as the animation stretches out and also makes one's face in the shape of that animal.

A post shared by Craig Lewis (@iamcraiglewis2) on Apr 28, 2020 at 1:48am PDT

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One can go on Instagram's story camera and select the 'Browse Effects' section. The next step is to search for the filter 'Genetics Scanner' on the Effects gallery. The filter option comes up and one can select it and use it.

A post shared by (Molly) (@iheartmills_) on Apr 28, 2020 at 12:06pm PDT

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A post shared by Kelly Marie (@kellykatclark) on Apr 28, 2020 at 11:53am PDT

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A post shared by TRIITH (@jacob.fj) on Apr 28, 2020 at 9:01am PDT

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How to find Genetic Heritage Instagram filter? Here is how to use the fun filter - Republic World - Republic World

Genetics

Syphilis Alters Its Genetics to Evade the Immune System – SciTechDaily

A watercolor-like illustration of Treponema pallidum, the bacterium that causes syphilis. Credit: Alice C. Gray

By shuffling DNA in and out of one gene, syphilis stays a step ahead of the immune system to resist eradication.

The bacterium that causes syphilis, Treponema pallidum, likely uses a single gene to escape the immune system, research from UW Medicine in Seattle suggests.

The finding may help explain how syphilis can hide in the body for decades, thereby frustrating the immune systems attempts to eradicate it. It might also account for the bacteriums ability to re-infect people who had been previously been infected and should have acquired some immunity to it.

Although syphilis remains easily treated with penicillin, infection rates in the United States have increased steadily over the past two decades. The count rose to more than 115,000 new U.S. cases of the infection in 2018.

Worldwide there are an estimated 6 million new cases of syphilis among adults. The infection is responsible for an estimated 300,000 fetal and neonatal deaths annually.

However, despite its importance as a cause of disease, relatively little is known about the biology of Treponema pallidum.

One reason for this is that until recently it was impossible to grow it in a laboratory dish. As a consequence, many of the laboratory tools used to study other bacteria had not been developed for syphilis specifically.

In a new study, researchers compared the genomes of syphilis bacteria collected from a man who had been infected four times. He was enrolled in a UW Medicine study of spinal fluid abnormalities in individuals with syphilis conducted by Dr. Christina Marra, professor of neurolgy.

The samples were derived from his blood during two infections that occurred six years apart. Between those infections he had been infected and treated two additional times.

The researchers wanted to see if there were differences between the genomes of bacteria from the first and last infection. These differences might reveal how the genes of the bacteria had changed and how those changes might have enabled the bacteria to infect a person whose immune system had already seen and mounted an immune response to several different strains of syphilis.

Surprisingly, the researchers found that there were very few changes between the genomes from the two different samples except for one gene.

Across the about 1.1 million bases that make up the bacterias genome there were about 20 changes total. Thats very low, said Dr. Alex Greninger, assistant professor of laboratory medicine at the UW School of Medicine, who led the research project. But on this one gene, we saw hundreds of changes.

That gene, called Treponema pallidum repeat gene K (tprK), provides the instructions for the synthesis of a protein found on the surface of the bacterium. Proteins on the surface of a bacterium are typically more easily seen by immune cells and so are often prime targets for immune attack.

The study builds on decades of work from Drs. Sheila Lukehart and Arturo Centurion-Lara in the Department of Medicine at the University of Washington School of Medicine.

They first showed that TprK generated considerable diversity across seven discrete regions in which DNA sequences from elsewhere in the bacteriums genome could be swapped in and out. This process is called gene conversion.

Work in their lab demonstrated that bacterial cells with new tprK variants can evade the immune response to cause a persistent infection that can lead to the later stages of syphilis.

Amin Addetia, a research scientist in Greningers lab and lead author on the study, said it was as though the bacterium has a deck of cards in its genome from which it can draw and deal to these variable regions, essentially changing the proteins hand. These substitutions change the proteins appearance on the surface to allow it to elude the immune system.

Ive looked at a lot of bacterial genomes, Addetia said, and theyre a lot more interesting than the Treponemas, except for this one gene.It can generate an astounding number of diverse sequences within these variable regions without impairing the proteins ability to function.

Although bacteria, viruses and parasites may have many proteins on their surfaces that the immune system could detect and attack, in many cases only one protein seems to attract most of the attention. Such proteins are called immunodominant.

They may protect the bacterium by catching the immune systems attention, Greninger said. The protein acts like a distraction that draws the immune system away from proteins that might be the bacteriums Achilles heel. More work will be required to determine if this is the case in TprK.

Greninger said he hoped the findings might help researchers develop vaccines that allow the immune system either to attack TprK more effectively or to ignore TprK and target other, less variable syphilis proteins.

###

Reference: Comparative Genomics and Full-Length TprK Profiling of Treponema pallidum subsp. pallidum Reinfection by Amin Addetia, Lauren C. Tantalo, Michelle J. Lin, Hong Xie, Meei-Li Huang, Christina M. Marra, Alexander L. Greninger, PLOS Neglected Tropical Diseases.DOI: 10.1371/journal.pntd.0007921

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Syphilis Alters Its Genetics to Evade the Immune System - SciTechDaily

Physiology

Virus-Infected Bees More Likely to Access Healthy Hives – Lab Manager Magazine

Entomology professor Adam Dolezal and his colleagues found that infection with the Israeli acute paralysis virus increases the likelihood that infected bees are accepted by foreign colonies.

Fred Zwicky

CHAMPAIGN, IL Honey bees that guard hive entrances are twice as likely to allow in trespassers from other hives if the intruders are infected with the Israeli acute paralysis virus, a deadly pathogen of bees, researchers report.

Their new study, reported in theProceedings of the National Academy of Sciences, strongly suggests that IAPV infection alters honey bees' behavior and physiology in ways that boost the virus's ability to spread, the researchers say.

"The most important finding of our study is that IAPV infection increases the likelihood that infected bees are accepted by foreign colonies," said Adam Dolezal, a professor of entomology at the University of Illinois (U of I) at Urbana-Champaign who led the new research. "Somehow, the infected bees are able to circumvent the guards of foreign colonies, which they shouldn't be able to do."

Previous studies have shown that IAPV-infected honey bees are more likely than healthy bees to lose their way when returning home from foraging trips. In commercial beekeeping operations where hives are stacked much closer together than in the wild, the virus is even more likely to spread from one infected colony to nearby healthy ones.

To capture the behavior of individual bees, researchers tagged each one with the equivalent of a QR code and continuously monitored their interactions. The scientists were able to simultaneously track the behaviors of as many as 900 bees.

Researchers tagged each honey bee with the equivalent of a QR code and used an automated system to study trophallaxis, a process by which the bees exchange regurgitated food and other liquids. The system allowed them to track how infection with IAPV affected the bees' trophallaxis social network.

Tim Gernat

In previous work, study co-author U of I entomologist Gene Robinson and his colleagues developed this automated system to study bees engaged in trophallaxis, a process by which honey bees exchange regurgitated food and other liquids. They used this system to study how IAPV infection might affect the bees' trophallaxis social network.

"Honey bees use trophallaxis to share food with each other as well as hormones and other signaling molecules that can affect their physiology and behavior. They do it in pairs by touching their mouthparts and antennae, and each bee does this with hundreds of partners a day," said Robinson, who directs the Carl R. Woese Institute for Genomic Biology at Illinois. "Trophallaxis is essential to the spread of information and nutrition throughout the hive, but unfortunately, a behavior performed with such close social contact also allows viral infections to be transmitted through a hive."

In the new study, the scientists saw that honey bees altered their behavior in response to infection in their own hives. IAPV-infected beesand bees that had had their immune systems stimulated to mimic infectionengaged in less trophallaxis than their healthy counterparts did.

The infected bees were just as mobile as the other bees, so their lower rates of trophallaxis were not the result of sluggishness from being sick, Dolezal said. The researchers believe this change in behavior is a general response to a health threat and not specific to IAPV infection, which is in line with previous research.

Honey bees touch their mouthparts and antennae together to share food and information, but the practice also can transmit viruses.

Fred Zwicky

When the scientists placed honey bee workers at the entrance of a foreign hive, however, the infected bees engaged in more trophallaxis with the guards, the researchers found. The guards were more likely to admit them than to let in healthy bees or bees whose immune systems had been stimulated. This response was specific to IAPV infection.

"Something about them must be different," Dolezal said.

To test whether the IAPV-infected bees were giving off a different chemical odor than their healthy nest mates, the researchers analyzed the chemistry of the hydrocarbons that coat the bees' exoskeletons. They discovered distinct hydrocarbon profiles for healthy bees, IAPV-infected bees and immunostimulated bees.

"It seems that the virus is changing how the bees smell, and perhaps the infected bees also are behaving in a way that is meant to appease the guards by engaging more in trophallaxus," Dolezal said.

The new findings suggest that IAPV is evolving in ways that enhance its ability to infect as many hosts as possible, Dolezal said.

"If you're a virus, it's much more valuable to get transmitted to a new family group, like traveling from one city to a new city," he said. "And so how do you get there? You increase the chances that the sick bees leaving colony A are more likely to get into colony B."

- This press release was originally published on theIllinois News Bureau website

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Virus-Infected Bees More Likely to Access Healthy Hives - Lab Manager Magazine

Physiology

Study: Protein known to expand blood vessels works differently in males and females – News-Medical.Net

A protein known to expand blood vessels -- key to controlling conditions like high blood pressure -- actually has different functions in males and females, new UC Davis Health research shows.

Conducted using arterial cells from mice, the study is the first to identify sex-based distinctions in how the protein --Kv2.1 -- works.

Kv2.1 is generally known to form calcium channels that dilate blood vessels. In arterial cells from female mice, however, it contracted blood vessels.

The research was led by Luis Fernando Santana, professor and chair of physiology and membrane biology, and graduate student Samantha O'Dwyer. It is published in the Proceedings of the National Academy of Sciences.

"We were shocked at the difference and the strength of that difference," Santana said. "We think we've found the physiological explanation for what some of our clinical colleagues are seeing in patients ? some high blood pressure medications tend to work better for men, while others work better for women."

Santana and his team study calcium channels, their effects on heart muscle cells and how to alter that process to improve treatments for cardiovascular disease. They are especially interested in finding new treatments for hypertension, because it affects 45% of adults in the U.S. and is linked with serious conditions such as stroke, heart failure and aneurysm.

The current study focused on how Kv2.1 changes calcium channel organization and function. The investigators found that Kv2.1 promotes tight clustering of calcium channels. Kv2.1 expression is higher in cells from female mice, leading to larger clusters. This caused higher calcium levels in arterial cells and vasoconstriction. In arterial cells from male mice, Kv2.1 expression was not as high and calcium channel clusters were much smaller, causing vasodilation.

"This difference can only be attributed to the sex of the research mice," Santana said.

The next step, Santana said, is to determine what causes the different roles of Kv2.1. He plans to investigate the potential that sex hormones regulate the protein in arterial cells. His ultimate goal is tailored treatment strategies for hypertension for men and women.

"Until recently, the research community only used male mice to investigate heart disease," Santana said. "Our study proves what a major oversight that has been."

Other researchers on the study were Stephanie Palacio, Collin Matsumoto, Laura Guarina, Nicholas Klug, Sendoa Tajada, Barbara Rosati, David McKinnon and James Trimmer, all of UC Davis. Rosati also is affiliated with the State University of New York.

The study was supported by grants from the National Institutes of Health (grant numbers 5R01HL085686, 1R01HL144071, 1OT2OD026580 and T32HL086350) and the American Heart Association.

"Kv2.1 Channels Play Opposing Roles in Regulating Membrane Potential, Ca2+ Channel Function, and Myogenic Tone in Arterial Smooth Muscle" is available online.

Source:

Journal reference:

ODwyer, S. C., et al. (2020) Kv2.1 channels play opposing roles in regulating membrane potential, Ca2+ channel function, and myogenic tone in arterial smooth muscle. Proceedings of National Academy of Sciences. doi.org/10.1073/pnas.1917879117.

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Study: Protein known to expand blood vessels works differently in males and females - News-Medical.Net

Embryology

Coronavirus-hit mum gives birth to magic IVF baby six weeks premature in a hospital bereavement room – The Sun

A MUM battling coronavirus has given birth to a "magic" IVF baby six weeks premature in a hospital bereavement room.

Claire Trusson, 37, fell pregnant after having IVF treatment following two years of struggling to start a family with husband Murray Mitchell, 33.

Just weeks before Claire was due, she started to experience cold-like symptoms which soon developed into a persistent cough.

She went into isolation, until she started experiencing contractions and was rushed to St Helier Hospital in Carshalton, near Sutton in South-West London.

While in hospital, medics had to put her in the most isolated room on the ward to keep her away from all others - which turned out to be the bereavement delivery room.

Claire went home and a day later tested positive for the virus - but found herself back in the bereavement suite just a week later on March 30 to safely give birth to baby Jake.

In the scheme of things, I am super lucky - I'm well, he's well and really it's amazing

The first-time mum said giving birth six weeks early while suffering from the virus was stressful, and she didn't expect to give birth in the bereavement room.

Claire said: "I found out this week that that's the bereavement room - that's where they put families with their stillborn babies so they can have some time with them.

"They have a memorial clock on the wall, and because I was timing my contractions when I was first in there, I spent a lot of time staring at that clock."

But she added that she was "really grateful" to have given birth to baby Jake and avoid "another six weeks of anxiety of what giving birth would look like".

She added: "In the scheme of things, I am super lucky - I'm well, he's well and really it's amazing."

What is IVF Treatment?

After struggling to conceive for two years, Claire and her husband received IVF on the NHS and a single egg was implanted in August 2019.

IVF is one of the most successful fertility treatments, and has given birth to 8 million babies worldwide.

The success rate is dependent on multiple factors, and range from 7 per cent to 29 per cent, according to the Human Fertilisation and Embryology Authority.

But despite her joy at having baby Jake, Claire is still concerned about passing the virus onto him due to a lack of face masks.

On the way home from hospital, Jake met his grandmother Angela and uncle David through the car window.

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She added: "Every little sneeze and every little cough and every little cry, I jump on him like, 'oh god, you've got coronavirus.'

"It sounds really reckless, but it's really hard to look after a baby and them not see your face - and I didn't really have any face masks."

"I'm just trying not to breathe on him."

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The Sun has launched an appeal to raise 1MILLION for NHS workers. The Who Cares Wins Appeal aims to get vital support to staff in their hour of need.

We have teamed up with NHS Charities Together in their urgent Covid-19 Appeal to ensure the money gets to exactly who needs it.

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Embryology

Letter: Response to the Rev. Dr. Matthew Johnson – Rockford Register Star

TuesdayApr28,2020at7:15PM

The Register Star ran an interesting editorial by The Rev. Dr. Matthew Johnson. His article is titled "Everyone is worthy of care and inclusion." Johnson is "pro-choice" when it comes to the brutal and vicious dismembering of children in the womb. What he fails to realize, as most abortion supporters fail to realize, is that when they say it should be a legal "choice" to kill a beautiful living little girl or boy in the womb, they are also saying not all people are worthy of care even though science, embryology, 3D and 4D ultrasound technology, theology, human reason and basic decency prove abortion is the killing of a member of our human family.

Johnson says government decisions in regards to reopening the economy should be "guided by justice, compassion, and concern for human dignity." Every abortion is the murder of a child who is a full member of our human family. Abortion destroys justice, compassion and the human dignity of all involved in the act of killing a baby.

Johnson wrote "we cannot and should not have second-class citizenship for anyone." The crushing of the skull and stopping of the beating heart of a person in the womb is a crime against life and the basic human rights of a person in the womb.

He closes his article with, "Everyone is worthy of care and inclusion. No exceptions." He is right, we should have no exceptions to love and respect for all people. We must end the unjust and barbaric legal killing of our preborn sisters and brothers in the womb.

Kevin Rilott, Rockford

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Letter: Response to the Rev. Dr. Matthew Johnson - Rockford Register Star

Biochemistry

In-depth Analysis of How COVID-19 is Impacting the Automatic Biochemistry Analyzers Market | Business Opportunities, Current Trends, Challenges and…

Due to the pandemic, we have included a special section on the Impact of COVID 19 on the Automatic Biochemistry Analyzers Market which would mention How the Covid-19 is Affecting the Automatic Biochemistry Analyzers Industry, Market Trends and Potential Opportunities in the COVID-19 Landscape, Covid-19 Impact on Key Regions and Proposal for Automatic Biochemistry Analyzers Players to Combat Covid-19 Impact.

The Global Automatic Biochemistry Analyzers Market has been garnering remarkable momentum in the recent years. The steadily escalating demand due to improving purchasing power is projected to bode well for the global market. QY Researchs latest publication, Titled [Automatic Biochemistry Analyzers Market Research Report 2020], offers an insightful take on the drivers and restraints present in the market. It assesses the historical data pertaining to the global Automatic Biochemistry Analyzers market and compares it to the current market trends to give the readers a detailed analysis of the trajectory of the market. A team subject-matter experts have provided the readers a qualitative and quantitative data about the market and the various elements associated with it.

Key companies operating in the global Automatic Biochemistry Analyzersmarket include_Roche, Danaher, Siemens Healthcare, Abbott, Hitachi, Mindray Medical, Thermo Scientific, KHB, Abaxis, Horiba Medical, ELITech, Gaomi Caihong, Sunostik, Senlo, Sysmex, Urit, Tecom Science, Randox Laboratories, Dirui, Adaltis, Rayto

Get PDF Sample Copy of the Report to understand the structure of the complete report: (Including Full TOC, List of Tables & Figures, Chart) :

https://www.qyresearch.com/sample-form/form/1651409/global-automatic-biochemistry-analyzers-industry-research-report-growth-trends-and-competitive-analysis-2020-2026

The Essential Content Covered in the Global Automatic Biochemistry Analyzers Market Report:Top Key Company Profiles.Main Business and Rival InformationSWOT Analysis and PESTEL AnalysisProduction, Sales, Revenue, Price and Gross MarginMarket Size And Growth RateCompany Market Share

Segmental Analysis :

The report has classified the global Automatic Biochemistry Analyzers industry into segments including product type and application. Every segment is evaluated based on growth rate and share. Besides, the analysts have studied the potential regions that may prove rewarding for the Automatic Biochemistry Analyzers manufcaturers in the coming years. The regional analysis includes reliable predictions on value and volume, thereby helping market players to gain deep insights into the overall Automatic Biochemistry Analyzers industry.

Global Automatic Biochemistry Analyzers Market Segment By Type:

Floor-standing, Bench-top

Global Automatic Biochemistry Analyzers Market Segment By Applications:

Primary Hospital, Provincial Hospital, Prefectural Hospital

Critical questions addressed by the Automatic Biochemistry Analyzers Market report

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Table Of Content

1 Report Overview1.1 Research Scope1.2 Top Automatic Biochemistry Analyzers Manufacturers Covered: Ranking by Revenue1.3 Market Segment by Type1.3.1 Global Automatic Biochemistry Analyzers Market Size by Type: 2015 VS 2020 VS 2026 (US$ Million)1.3.2 Floor-standing1.3.3 Bench-top1.4 Market Segment by Application1.4.1 Global Automatic Biochemistry Analyzers Consumption by Application: 2015 VS 2020 VS 20261.4.2 Primary Hospital1.4.3 Provincial Hospital1.4.4 Prefectural Hospital1.6 Coronavirus Disease 2019 (Covid-19): Automatic Biochemistry Analyzers Industry Impact1.6.1 How the Covid-19 is Affecting the Automatic Biochemistry Analyzers Industry1.6.1.1 Automatic Biochemistry Analyzers Business Impact Assessment Covid-191.6.1.2 Supply Chain Challenges1.6.1.3 COVID-19s Impact On Crude Oil and Refined Products1.6.2 Market Trends and Automatic Biochemistry Analyzers Potential Opportunities in the COVID-19 Landscape1.6.3 Measures / Proposal against Covid-191.6.3.1 Government Measures to Combat Covid-19 Impact1.6.3.2 Proposal for Automatic Biochemistry Analyzers Players to Combat Covid-19 Impact1.7 Study Objectives1.8 Years Considered

2 Global Market Perspective2.1 Global Automatic Biochemistry Analyzers Production Capacity Analysis2.1.1 Global Automatic Biochemistry Analyzers Production Value (2015-2026)2.1.2 Global Automatic Biochemistry Analyzers Production (2015-2026)2.1.3 Global Automatic Biochemistry Analyzers Capacity (2015-2026)2.1.4 Global Automatic Biochemistry Analyzers Marketing Pricing and Trends2.2 Global Automatic Biochemistry Analyzers Market Size Growth Potential by Key Producing Regions2.2.1 Global Automatic Biochemistry Analyzers Market Size by Key Producing Regions: 2015 VS 2021 VS 20262.2.2 Global Automatic Biochemistry Analyzers Market Share by Key Producing Regions: 2021 VS 20262.3 Industry Trends2.3.1 Market Top Trends2.3.2 Market Drivers2.3.3 Primary Interviews with Key Automatic Biochemistry Analyzers Players: Views for Future

3 Market Share by Manufacturers3.1 Global Top Manufacturers by Automatic Biochemistry Analyzers Production Capacity3.1.1 Global Top Manufacturers by Automatic Biochemistry Analyzers Production Capacity (2015-2020)3.1.2 Global Top Manufacturers by Automatic Biochemistry Analyzers Production (2015-2020)3.1.3 Global 5 and 10 Largest Manufacturers by Automatic Biochemistry Analyzers Production in 20193.2 Global Top Manufacturers by Automatic Biochemistry Analyzers Revenue3.2.1 Global Top Manufacturers by Automatic Biochemistry Analyzers Revenue (2015-2020)3.2.2 Global Top Manufacturers Market Share by Automatic Biochemistry Analyzers Revenue (2015-2020)3.2.3 Global Automatic Biochemistry Analyzers Market Concentration Ratio (CR5 and HHI)3.3 Global Top Manufacturers Market Share by Company Type (Tier 1, Tier 2 and Tier 3) (based on the Revenue in Automatic Biochemistry Analyzers as of 2019)3.4 Global Automatic Biochemistry Analyzers Average Selling Price (ASP) by Manufacturers3.5 Key Manufacturers Automatic Biochemistry Analyzers Plants/Factories Distribution and Area Served3.6 Date of Key Manufacturers Enter into Automatic Biochemistry Analyzers Market3.7 Key Manufacturers Automatic Biochemistry Analyzers Product Offered3.8 Mergers & Acquisitions, Expansion Plans

4 Estimate and Forecast by Type (2015-2026)4.1 Global Automatic Biochemistry Analyzers Historic Market Size by Type (2015-2020)4.1.2 Global Automatic Biochemistry Analyzers Production Market Share by Type (2015-2020)4.1.3 Global Automatic Biochemistry Analyzers Production Value Market Share by Type4.1.4 Automatic Biochemistry Analyzers Average Selling Price (ASP) by Type (2015-2020)4.2 Global Automatic Biochemistry Analyzers Market Size Forecast by Type (2021-2026)4.2.2 Global Automatic Biochemistry Analyzers Production Market Share Forecast by Type (2021-2026)4.2.3 Global Automatic Biochemistry Analyzers Production Value Market Share Forecast by Type4.2.4 Automatic Biochemistry Analyzers Average Selling Price (ASP) Forecast by Type (2021-2026)4.3 Global Automatic Biochemistry Analyzers Market Share by Price Tier (2015-2020): Low-End, Mid-Range and High-End

5 Market Size by Application (2015-2026)5.1 Global Automatic Biochemistry Analyzers Consumption by Application (2015-2020)5.2 Global Automatic Biochemistry Analyzers Consumption by Application (2021-2026)

6 Production by Regions: Market Fact & Figures6.1 Global Automatic Biochemistry Analyzers Production (History Data) by Regions (2015-2020)6.2 Global Automatic Biochemistry Analyzers Production Value (History Data) by Regions6.3 North America6.3.1 North America Automatic Biochemistry Analyzers Production Growth Rate (2015-2020)6.3.2 North America Automatic Biochemistry Analyzers Production Value Growth Rate (2015-2020)6.3.3 Key Players Market Share in North America6.3.4 North America Automatic Biochemistry Analyzers Import & Export (2015-2020)6.4 Europe6.4.1 Europe Automatic Biochemistry Analyzers Production Growth Rate (2015-2020)6.4.2 Europe Automatic Biochemistry Analyzers Production Value Growth Rate (2015-2020)6.4.3 Key Players Market Share in Europe6.4.4 Europe Automatic Biochemistry Analyzers Import & Export (2015-2020)6.5 China6.5.1 China Automatic Biochemistry Analyzers Production Growth Rate (2015-2020)6.5.2 China Automatic Biochemistry Analyzers Production Value Growth Rate (2015-2020)6.5.3 Key Players Market Share in China6.5.4 China Automatic Biochemistry Analyzers Import & Export (2015-2020)6.6 Japan6.6.1 Japan Automatic Biochemistry Analyzers Production Growth Rate (2015-2020)6.6.2 Japan Automatic Biochemistry Analyzers Production Value Growth Rate (2015-2020)6.6.3 Key Players Market Share in Japan6.6.4 Japan Automatic Biochemistry Analyzers Import & Export (2015-2020)

7 Automatic Biochemistry Analyzers Consumption by Regions: Market Fact & Figures7.1 Global Automatic Biochemistry Analyzers Consumption (History Data) by Regions (2015-2020)7.2 Global Top Automatic Biochemistry Analyzers Consumers (regions/countries) Ranking and Share of Total Automatic Biochemistry Analyzers Consumption in 2015 VS 20197.3 North America7.3.1 North America Automatic Biochemistry Analyzers Consumption by Type7.3.2 North America Automatic Biochemistry Analyzers Consumption by Application7.3.3 North America Automatic Biochemistry Analyzers Consumption by Countries7.3.4 U.S.7.3.5 Canada7.4 Europe7.4.1 Europe Automatic Biochemistry Analyzers Consumption by Type7.4.2 Europe Automatic Biochemistry Analyzers Consumption by Application7.4.3 Europe Automatic Biochemistry Analyzers Consumption by Countries7.4.4 Germany7.4.5 France7.4.6 U.K.7.4.7 Italy7.4.8 Russia7.5 Asia Pacific7.5.1 Asia Pacific Automatic Biochemistry Analyzers Consumption by Type7.5.2 Asia Pacific Automatic Biochemistry Analyzers Consumption by Application7.5.3 Asia Pacific Automatic Biochemistry Analyzers Consumption by Regions7.5.4 China7.5.5 Japan7.5.6 South Korea7.5.7 India7.5.8 Australia7.5.9 Taiwan7.5.10 Indonesia7.5.11 Thailand7.5.12 Malaysia7.5.13 Philippines7.5.14 Vietnam7.6 Central & South America7.6.1 Central & South America Automatic Biochemistry Analyzers Consumption by Type7.6.2 Central & South America Automatic Biochemistry Analyzers Consumption by Application7.6.3 Central & South America Automatic Biochemistry Analyzers Consumption by Countries7.6.4 Mexico7.6.5 Brazil7.6.6 Argentina7.7 Middle East and Africa7.7.1 Middle East and Africa Automatic Biochemistry Analyzers Consumption by Type7.7.2 Middle East and Africa Automatic Biochemistry Analyzers Consumption by Application7.7.3 Central & South America Automatic Biochemistry Analyzers Consumption by Countries7.7.4 Turkey7.7.5 Saudi Arabia7.7.6 UAE

8 Company Profiles8.1 Roche8.1.1 Roche Corporation Information8.1.2 Roche Business Overview and Total Revenue (2019 VS 2018)8.1.3 Roche Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.1.4 Automatic Biochemistry Analyzers Products and Services8.1.5 Roche SWOT Analysis8.1.6 Roche Recent Developments8.2 Danaher8.2.1 Danaher Corporation Information8.2.2 Danaher Business Overview and Total Revenue (2019 VS 2018)8.2.3 Danaher Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.2.4 Automatic Biochemistry Analyzers Products and Services8.2.5 Danaher SWOT Analysis8.2.6 Danaher Recent Developments8.3 Siemens Healthcare8.3.1 Siemens Healthcare Corporation Information8.3.2 Siemens Healthcare Business Overview and Total Revenue (2019 VS 2018)8.3.3 Siemens Healthcare Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.3.4 Automatic Biochemistry Analyzers Products and Services8.3.5 Siemens Healthcare SWOT Analysis8.3.6 Siemens Healthcare Recent Developments8.4 Abbott8.4.1 Abbott Corporation Information8.4.2 Abbott Business Overview and Total Revenue (2019 VS 2018)8.4.3 Abbott Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.4.4 Automatic Biochemistry Analyzers Products and Services8.4.5 Abbott SWOT Analysis8.4.6 Abbott Recent Developments8.5 Hitachi8.5.1 Hitachi Corporation Information8.5.2 Hitachi Business Overview and Total Revenue (2019 VS 2018)8.5.3 Hitachi Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.5.4 Automatic Biochemistry Analyzers Products and Services8.5.5 Hitachi SWOT Analysis8.5.6 Hitachi Recent Developments8.6 Mindray Medical8.6.1 Mindray Medical Corporation Information8.6.2 Mindray Medical Business Overview and Total Revenue (2019 VS 2018)8.6.3 Mindray Medical Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.6.4 Automatic Biochemistry Analyzers Products and Services8.6.5 Mindray Medical SWOT Analysis8.6.6 Mindray Medical Recent Developments8.7 Thermo Scientific8.7.1 Thermo Scientific Corporation Information8.7.2 Thermo Scientific Business Overview and Total Revenue (2019 VS 2018)8.7.3 Thermo Scientific Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.7.4 Automatic Biochemistry Analyzers Products and Services8.7.5 Thermo Scientific SWOT Analysis8.7.6 Thermo Scientific Recent Developments8.8 KHB8.8.1 KHB Corporation Information8.8.2 KHB Business Overview and Total Revenue (2019 VS 2018)8.8.3 KHB Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.8.4 Automatic Biochemistry Analyzers Products and Services8.8.5 KHB SWOT Analysis8.8.6 KHB Recent Developments8.9 Abaxis8.9.1 Abaxis Corporation Information8.9.2 Abaxis Business Overview and Total Revenue (2019 VS 2018)8.9.3 Abaxis Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.9.4 Automatic Biochemistry Analyzers Products and Services8.9.5 Abaxis SWOT Analysis8.9.6 Abaxis Recent Developments8.10 Horiba Medical8.10.1 Horiba Medical Corporation Information8.10.2 Horiba Medical Business Overview and Total Revenue (2019 VS 2018)8.10.3 Horiba Medical Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.10.4 Automatic Biochemistry Analyzers Products and Services8.10.5 Horiba Medical SWOT Analysis8.10.6 Horiba Medical Recent Developments8.11 ELITech8.11.1 ELITech Corporation Information8.11.2 ELITech Business Overview and Total Revenue (2019 VS 2018)8.11.3 ELITech Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.11.4 Automatic Biochemistry Analyzers Products and Services8.11.5 ELITech SWOT Analysis8.11.6 ELITech Recent Developments8.12 Gaomi Caihong8.12.1 Gaomi Caihong Corporation Information8.12.2 Gaomi Caihong Business Overview and Total Revenue (2019 VS 2018)8.12.3 Gaomi Caihong Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.12.4 Automatic Biochemistry Analyzers Products and Services8.12.5 Gaomi Caihong SWOT Analysis8.12.6 Gaomi Caihong Recent Developments8.13 Sunostik8.13.1 Sunostik Corporation Information8.13.2 Sunostik Business Overview and Total Revenue (2019 VS 2018)8.13.3 Sunostik Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.13.4 Automatic Biochemistry Analyzers Products and Services8.13.5 Sunostik SWOT Analysis8.13.6 Sunostik Recent Developments8.14 Senlo8.14.1 Senlo Corporation Information8.14.2 Senlo Business Overview and Total Revenue (2019 VS 2018)8.14.3 Senlo Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.14.4 Automatic Biochemistry Analyzers Products and Services8.14.5 Senlo SWOT Analysis8.14.6 Senlo Recent Developments8.15 Sysmex8.15.1 Sysmex Corporation Information8.15.2 Sysmex Business Overview and Total Revenue (2019 VS 2018)8.15.3 Sysmex Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.15.4 Automatic Biochemistry Analyzers Products and Services8.15.5 Sysmex SWOT Analysis8.15.6 Sysmex Recent Developments8.16 Urit8.16.1 Urit Corporation Information8.16.2 Urit Business Overview and Total Revenue (2019 VS 2018)8.16.3 Urit Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.16.4 Automatic Biochemistry Analyzers Products and Services8.16.5 Urit SWOT Analysis8.16.6 Urit Recent Developments8.17 Tecom Science8.17.1 Tecom Science Corporation Information8.17.2 Tecom Science Business Overview and Total Revenue (2019 VS 2018)8.17.3 Tecom Science Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.17.4 Automatic Biochemistry Analyzers Products and Services8.17.5 Tecom Science SWOT Analysis8.17.6 Tecom Science Recent Developments8.18 Randox Laboratories8.18.1 Randox Laboratories Corporation Information8.18.2 Randox Laboratories Business Overview and Total Revenue (2019 VS 2018)8.18.3 Randox Laboratories Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.18.4 Automatic Biochemistry Analyzers Products and Services8.18.5 Randox Laboratories SWOT Analysis8.18.6 Randox Laboratories Recent Developments8.19 Dirui8.19.1 Dirui Corporation Information8.19.2 Dirui Business Overview and Total Revenue (2019 VS 2018)8.19.3 Dirui Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.19.4 Automatic Biochemistry Analyzers Products and Services8.19.5 Dirui SWOT Analysis8.19.6 Dirui Recent Developments8.20 Adaltis8.20.1 Adaltis Corporation Information8.20.2 Adaltis Business Overview and Total Revenue (2019 VS 2018)8.20.3 Adaltis Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.20.4 Automatic Biochemistry Analyzers Products and Services8.20.5 Adaltis SWOT Analysis8.20.6 Adaltis Recent Developments8.21 Rayto8.21.1 Rayto Corporation Information8.21.2 Rayto Business Overview and Total Revenue (2019 VS 2018)8.21.3 Rayto Automatic Biochemistry Analyzers Production Capacity, Revenue, Average Selling Price (ASP) and Gross Margin (2015-2020)8.21.4 Automatic Biochemistry Analyzers Products and Services8.21.5 Rayto SWOT Analysis8.21.6 Rayto Recent Developments

9 Automatic Biochemistry Analyzers Production Side by Producing Regions (Countries)9.1 Global Automatic Biochemistry Analyzers Production Value Forecast by Region (2021-2026)9.2 Automatic Biochemistry Analyzers Production Forecast by Regions9.3 Key Automatic Biochemistry Analyzers Producing Regions Forecast9.3.1 North America9.3.2 Europe9.3.3 China9.3.4 Japan

10 Automatic Biochemistry Analyzers Consumption Forecast by Top Consumers (Regions/Countries)10.1 Global Automatic Biochemistry Analyzers Consumption Forecast by Region (2021-2026)10.2 North America Market Consumption YoY Growth Forecast10.2.1 North America Automatic Biochemistry Analyzers Consumption YoY Growth (2021-2026)10.2.2 North America Automatic Biochemistry Analyzers Consumption Forecast by Country (2021-2026)10.3 Europe Market Consumption YoY Growth Forecast10.3.1 Europe Automatic Biochemistry Analyzers Consumption YoY Growth (2021-2026)10.3.2 Europe Automatic Biochemistry Analyzers Consumption Forecast by Country (2021-2026)10.4 Asia Pacific Market Consumption YoY Growth Forecast10.4.1 Asia Pacific Automatic Biochemistry Analyzers Consumption YoY Growth (2021-2026)10.4.1 Asia Pacific Automatic Biochemistry Analyzers Consumption Forecast by Regions (2021-2026)10.5 Latin America Market Consumption YoY Growth Forecast10.5.1 Latin America Automatic Biochemistry Analyzers Consumption YoY Growth (2021-2026)10.5.2 Latin America Automatic Biochemistry Analyzers Consumption Forecast by Country (2021-2026)10.6 Middle East and Africa Market Consumption YoY Growth Forecast10.6.1 Middle East and Africa Automatic Biochemistry Analyzers Consumption YoY Growth (2021-2026)10.6.2 Middle East and Africa Automatic Biochemistry Analyzers Consumption Forecast by Country (2021-2026)

11 Value Chain and Sales Channels Analysis11.1 Value Chain Analysis11.2 Sales Channels Analysis11.2.1 Automatic Biochemistry Analyzers Sales Channels11.2.2 Automatic Biochemistry Analyzers Distributors11.3 Automatic Biochemistry Analyzers Customers

12 Opportunities & Challenges, Threat and Affecting Factors12.1 Market Opportunities12.2 Market Challenges12.3 Porters Five Forces Analysis

13 Key Findings

14 Appendix14.1 Research Methodology14.1.1 Methodology/Research Approach14.1.2 Data Source14.2 Author Details14.3 Disclaimer

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In-depth Analysis of How COVID-19 is Impacting the Automatic Biochemistry Analyzers Market | Business Opportunities, Current Trends, Challenges and...

Biochemistry

Suncor, Western University team up to make COVID-19 tests using wastewater tech – Financial Post

Suncor Energy Inc. has teamed up with Western University scientists to tackle the shortage of COVID-19 tests, using technology intended to treat wastewater from refineries to produce home testing kits.

The devices, which could be ready in a few months, would allow individuals to test small samples of bodily fluid, such as blood, for COVID-19 antibodies, and receive the results in minutes.

We started in mid-March and its been going very well, said Martin Flatley, a senior staff engineer at Suncors Sarnia, Ont., refinery. Western is about 100 kilometres down the road so its very easy to visit and bring samples. Were in constant contact all the time.

Suncor, the Calgary-based oilsands giant, had already been collaborating with a lab led by Western biochemistry professor Dr. Gregory Gloor when the fast-moving coronavirus swept through North America, forcing closures of non-essential operations and universities.

The team was attempting to identify and sequence genomes of organisms that naturally break down napthenic acid, a toxic byproduct that is part of the wastewater produced by the refinery.

One floor below Gloors lab at Western, fellow biochemistry professors David Edgell and Bogumil Karas were working with students to examine a specific type of algae that had been shown to produce proteins in large quantities.

Their lab is basically next door and we see them all the time, we talk to them all the time, we go out for beers, said Sam Slattery, a PhD candidate in Edgells lab and a lead researcher on the COVID-19 test project.

After the Suncor project was put on hold as COVID-19 hit, the leaders of the two labs wondered if the algae known as PT algae could produce the protein necessary to react with COVID-19 antibodies in a test. As part of the process, the Suncor technology could be used to sequence the protein and the algae.

Someone said lets see what the algae could do in this situation, said Slattery. Suncor said were on board and that was it.

The past couple of months have seen Flatley, Slattery and PhD student Daniel Giguere working around strict university COVID-19 protocols including a restriction that calls for only one person in the lab at any one time to produce and sequence the algae and its protein.

The process would be an alternative to current methods, which generate the protein using mammalian and insect cells. That procedure relies on far more costly materials, including a media the rich broth used to grow the protein that costs about $3,000 a litre compared to pennies a litre for the media used in the algae process.

The algae is photosynthetic too, so the energy it needs is free, we dont have to feed it, said Slattery.

The collaboration, funded by Suncor and Mitacs, a non-profit organization funded by provincial governments to promote innovation, and should have a workable test within a few months.

Epidemiologists have urged countries to dramatically ramp up testing for COVID-19, arguing that identifying and isolating infected individuals is essential to keeping the viruss spread under control until a vaccine is developed.

The call for testing has become even more urgent as provinces ponder reopening their economies, raising the risk of a second wave of infections. However, fierce global demand for tests has left countries competing for limited supplies as they attempt to develop and ramp up domestic production.

At the moment, the most commonly administered test is the nasopharyngeal swab, which identifies the active presence of the virus. The 6-inch swab is inserted through the nose by a medical professional.

However, scientists have been anxiously awaiting the development of both at-home tests and antibody tests that could measure those that have already been infected. Enabling individuals to administer their own tests could dramatically improve existing data on infections, particularly since the disease is carried by asymptomatic individuals.

If you have antibodies, you are probably over the infection, said Barry Bloom, a professor of public health at Harvard University and a specialist in infectious diseases. If you dont have the antibodies and dont have symptoms, thats where youre at risk of being infected, youre a threat. But the only way to know that is to test.

Financial Post

Email: npowell@nationalpost.com | Twitter:

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Suncor, Western University team up to make COVID-19 tests using wastewater tech - Financial Post

Biochemistry

Global Automatic Biochemistry Analyzers Market anticipated grow at a CAGR of xx% over the forecast period 2020-2025 :Roche, Horiba Medical, Danaher,…

The main objective of this research report is to present the comprehensive analysis about the factors which are responsible for the growth of the global Automatic Biochemistry Analyzers market. The study report covers all the recent developments and innovations in the market for a Automatic Biochemistry Analyzers. There are many government bodies, regulatory associations and universities are extending their help in the form of funds, investments and grants to promote research into the development of products of global Automatic Biochemistry Analyzers market. These activities of researching and funding are fuelling to the development of innovative products.

This study covers following key players:RocheHoriba MedicalDanaherAbbottHitachiSiemens HealthcareKHBMindray MedicalAbaxisThermo ScientificUritRandox LaboratoriesTecom ScienceELITechSenloSunostikAdaltisSysmexGaomi CaihongDiruiRayto

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Market segment by Type, the product can be split into Floor-standingBench-topMarket segment by Application, split into Primary HospitalProvincial HospitalPrefectural Hospital

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Some TOC Points:

1 Industry Overview of Automatic Biochemistry Analyzers2 Major Manufacturers Analysis of Automatic Biochemistry Analyzers3 Global Price, Sales and Revenue Analysis of Automatic Biochemistry Analyzers by Regions, Manufacturers, Types and ApplicationsContinued

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Some TOC Points:1 Scope of the Report2 Executive Summary3 Global Automatic Biochemistry Analyzers by Company4 Automatic Biochemistry Analyzers by RegionsContinued

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Global Automatic Biochemistry Analyzers Market anticipated grow at a CAGR of xx% over the forecast period 2020-2025 :Roche, Horiba Medical, Danaher,...