Anatomy

Greys Anatomy: The Worst Episode Of Each Season 9 Through 16, According To IMDb – Screen Rant

Grey's Anatomy is still going strong after 16 seasons. Here are the worst episodes, one per season, of seasons 9 through 16.

Medical drama Grey's Anatomy keeps pumping out season after season, each one filled with hit episodes that audiences can't get enough of. After sixteen seasons, the writers continue to find new stories and new characters that manage to keep viewers hooked time and time again.

RELATED: Every Sizzling Season Of Grey's Anatomy So Far, Ranked

Unfortunately, not every episode is a crowd pleaser, as theratings on Grey's Anatomy's IMDb page reflect. While everyone working on the show does their best,some episodes just don't do as well as others, and each season has one that fans votedas their least favorite.

When a tanker carrying gas explodes on the highway, several patients come into the hospital, but the danger is not over yet. One patient covered in gasoline ignores Bailey's and Owen's warnings and goes outside for a smoke. Inside the hospital, everyone hears a loud sound,which was the man suddenly becoming engulfed in flames. More patients come in, including a pregnant woman with an issue with her baby, as well as Matthew the paramedic, who was also at the scene of the accident.This and one other episode received a 7.4 score.

It's Halloween at the hospital, and the doctors are dealing with a somewhat creepy situation. A patient comes in after being bitten, and he is convinced that the person who bit him is a zombie. The biter comes in as welland is very violentwith has two bullet holes in his chest. While having difficulty finding his heartbeat, Leah gets bitten by him as well. After looking at his scans, the doctors discover that the man has a condition where his organs are mirrored to a typical person, which explains why he survived the gunshot wounds to the chest and why Leah couldn't find his heartbeat.

This episode has many fans angry, as it involves the death of a major character. After helping assist at the scene of an accident, Derek gets hit by a semi truck and is rushed to a nearby hospital. Derek knows he needs a CT scan, and so does one of the surgical residents. However, the attending doctor dismisses the idea.

RELATED: Grey's Anatomy: The 10 Worst Episodes According To IMDb

By the time it's discovered that his pupil is blown, signalling a brain injury, it's too late. Derek soon becomes brain dead, and Meredith arrives, signing the paperwork to remove his life support soon after.

Jackson and April have had a very complicated relationship, and this episode begins with the two of them signing papers to finalize a divorce between them. Then, there are flashbacks to their relationship from the beginning, showing a lot of happy times together. Among the flashbacks was the two of them after their baby Samuel's death, and it showed how each of them was having trouble with it in their own way. They also discuss how April going to Jordan would have negative consequences on their marriage, and indeed it did.

At the advice of Catherine, a woman named Eliza Minnick has been recently hired to revamp the surgical team at the hospital, pushing Webber out of his position. Jackson is not happy about this, and things are tense when the four of them have to work together. Since Jackson works on the hospital board as the Avery Foundation representative and has that power over his mother, he plans to use his position to make the changes that he sees fit in order to set things right by his opinion. One other episode this season also had a score of 6.2.

Owen and Amelia are enjoying spending time together, agreeing that a no-strings-attached agreement was a great idea. There's no time to think about that now though, because Owen has trauma certification classes to teach.

RELATED: Grey's Anatomy: 10 Facts About Owen Hunt Many Fans Don't Know

Jackson and Maggie are getting closer as well, but Jackson gets pulled away for a surgery with his mother and Richard. Meanwhile, Bailey and Jo are working on a patient named Marjorie who happens to be a famous astronautwhom Bailey has been following since she was a little girl.

Two episodes winlast place this season, and in this one, Maggie has accidentally spilled the beans about her origins. While being interviewed on a podcast and asked about why she became a surgeon, Maggie says that maybe it's in her blood, since her biological parents, Richard and Ellis, as well as her sister, Meredith, are all surgeons.Looks like the cat is out of the bag that she came from an affair between Ellis and Richard! While Meredith tries to assure Maggie that it will be okay, Richard is not happy about the secret getting out, as that is a part of his life that he is not very proud of.

Grey's fans seem to not like flashback episodes! In this one, Alex writes letters to Bailey, Meredith, and Jo, telling them that he has left. The episode goes on to show flashbacks and archive footage of his time at the hospital from thevery start to this point. Viewers get to see his relationship with Izzie, with whom Alex reveals he has had recent contact with. He found out that while she could not naturally have any childrenbecausethe cancer damaged her eggs, she did manage to have children with the embryos from when she was with Alex. Alex says in his letters that he has gone to see Izzie and their twins.

NEXT: Grey's Anatomy: Most Hated Supporting Characters, Ranked

Next 10 Best Plot Twists In Game Of Thrones, Ranked

Emily Bump has been writing her entire life. From stories to sonnets, she enjoys working in many genres. She was on her high school newspaper, and at 18 years old, she published a short novella entitled Must Keep Moving. Since then, she has continued writing, practicing privately for herself. When she is not writing, she enjoys expressing her creativity in other ways such as crafting and crocheting. Emily is excited to be a new staff writer, working with Valnet and ScreenRant to publish some new pieces, and she hopes to expand her writing even more with this opportunity!

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Greys Anatomy: The Worst Episode Of Each Season 9 Through 16, According To IMDb - Screen Rant

Anatomy

‘Grey’s Anatomy’ Creator Shonda Rhimes Says Women Need To Do More Of This – Showbiz Cheat Sheet

Media mogul Shonda Rhimes is known for her prime time television hits including Greys Anatomy, Scandal, and Private Practice. Now moving on to Netflix after signing a multi-million dollar development deal, Rhimes has firmly established herself as a producing powerhouse.

In a 2018 awards ceremony for Elles Women in Hollywood, Rhimes encouraged women to take up a new practice when it comes to their successes.

Since Greys Anatomys debut in 2005, Ellen Pompeo has portrayed Dr. Meredith Grey from intern to successful surgeon. Rhimes partnership with Pompeo for 15-plus years has become a force to be reckoned with.

Over the years on this show, Ellen and I have discovered how powerful we are both separately and together, Rhimes said at the awards ceremony, according to her website Shondaland.com. When Ellen and I are working together to get what we want,what we deserve, we make a truly terrifyingly powerful awesome pair of badass women warriors.

Rhimes noted that their successful collaboration gave them more clout as time went on. See, over the course of our 15 seasons, Ellen and I went from believing we were employees of a network to understanding WE were the network, the Greys creator explained.

RELATED: Greys Anatomy Creator Shonda Rhimes Reveals How A Moment of Extreme Horror Inspired Her Weight Loss

Pompeo fought for a huge salary bump after co-star Patrick Dempsey left the show in 2015 and wasnt shy about sharing her process in getting the raise. In an interview with the Hollywood Reporter, Pompeo openly shared how she fought for the wage she felt she deserved. Rhimes applauded her colleague for taking such a groundbreaking step for women.

A little while ago, in an inspiring article, Ellen told the world she was the highest paid woman in dramatic television, Rhimes recalled. She did not hide. She bragged. Shesaidshe was powerful. And she said she deserved it.

Rhimes also addressed the flak Pompeo soon received after the article was published. There was some blow back. And there should not have been, the television producer stated. I have seen a thousand articles like that from men. But shes a woman. And people felt she shouldnt say things like that.

RELATED:Greys Anatomy Creator Shonda Rhimes Just Signed This Legendary Actress for Her Netflix Series

The media mogul confessed that she felt compelled to hide her success in her agreement with Netflix for fear of a backlash. When I made a deal with Netflix, I let them report my salary wrong in the press and then did as few interviews as possible, Rhimes admitted. I put my head down and worked. In other words, I hid How can I inspire anyone if I am hiding?

After giving examples of Pompeos experience and her own, Rhimes came to a valuable conclusion. Women do not brag enough. The other day, I came to the conclusion that men brag and women hide, she said. And when men do deserve to brag oh my gosh, they are so good at it Men brag about EVERYTHING. Even things that arent things.

To illustrate her point, Rhimes decided to set an example. Let me take a deep breath. And on behalf of women everywhere and in the name of not leaving my sister hanging, I will brag, she stated, adding, I am the highest paid showrunner in television. And I deserve it.

The Netflix producer drove home her speech with reminding the audience to believe in themselves and stop hiding their successes.

RELATED:What Greys Anatomy Creator Shonda Rhimes Said About Working With Britney Spears

We need to set an example. I am awesome. We are awesome, Rhimes declared. Which is another way of saying we have power. We are powerful women. And when we say we have power, what we are really saying is, we DESERVE to have power. We DESERVE whatever good thing it is we are getting.

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'Grey's Anatomy' Creator Shonda Rhimes Says Women Need To Do More Of This - Showbiz Cheat Sheet

Anatomy

‘Grey’s Anatomy’ Creator Shonda Rhimes Was Treated After Her 100+ Pound Weight Loss: ‘Things Got Weird’ – Showbiz Cheat Sheet

Shonda Rhimes is known for developingsome of todays most popular television showsincludingGreys Anatomy, Scandal,andHow To Get Away with Murder.Now in partnership with Netflix, Rhimes is creating a suite of programs that are sure to bring in high numbers of viewers.

The mom of three embarked on a weight-loss journey several years ago which resulted in shedding over 100 pounds. Rhimes previously shared that her interactions with people were quite different after slimming down.

In her 2015 memoir Year of Yes, Rhimes chronicles her journey of saying yes to things that she normally shied away from and how that one small word changed her life.

I sat down and said, I really need to start saying yes to the things that scare me. If I never say yes to anything, I need to start saying yes to things that I would always say no to automatically, Rhimes shared in 2015, according to Parade. I promised myself that I would do it for just a year because I thought that I wasnt going to survive. I really thought, Im going to die of shame and shock and fear.

With a focus on tackling issues with an affirmative answer, Rhimes soon realized that her health had to be a part of her new quest.

RELATED: Greys Anatomy Creator Shonda Rhimes Shares How She Was Inspired by Oprah Winfrey

One of the yeses was, I cant say yes to everything and not say yes to taking care of yourself and not say yes to health, the Greys Anatomy creator revealed. That came from having an epiphany. I work so hard at everything that I do. I work my butt off at work and I work hard at being a mother, why do I think losing weight would be easy?

After losing almost 150.pounds, Rhimes discussed many aspects of the process in an article for her Shondaland newsletter subscribers. While the television producer was successful in achieving her goal, she did not enjoy the experience.

I did not do it because I thought I would become beautiful like in the movies,Rhimesexplained of her slim down, according to Health.com. I did it because I could not walk up a short flight up stairs without stopping to take a break and wiping sweat from my brow There is nothing fun or interesting or great about it. I hated losing weight. I hated every single second of it.

RELATED: ABC Says Shonda Rhimes and Ellen Pompeo Will Decide When Greys Anatomy Will End

Following her transformation, Rhimes soon noticed she was being perceived in a whole new light by others. You know what was worse than losing weight? What was SO MUCH MORE HORRIFYING? How people treated me after I lost weight, she wrote.I mean, things gotweird. Women I barely knew gushed. Like I was holding-a-new-baby-gushed. Only there was no new baby. It was just me And men? They spoke to me. THEY SPOKE TO ME. Like stood still and had long conversations with me about things.

Rather than finding it pleasing, Rhimes was put off by the change in how she was being treated.

It was disconcerting. But even more disconcerting was that all these people suddenly felt completely comfortable talking to me about my body, she wrote. Telling me I looked pretty or that they were proud of me. After I lost weight, I discovered that people found me valuable. Worthy of conversation. A person one could look at. A person one could compliment. A person one could admire.

Rhimes was stunned by the about-face from others. What the hell did they see me as before? How invisible was I to them then? she pondered. What value did they put on my presence at a party, a lunch, a discussion?

RELATED: The Sneaky Way Shonda Rhimes Helped Sandra Oh Nail Her Greys Anatomy Audition

The television producer summed up her thoughts by making a somber discovery.When I was fat, I wasnt a PERSON to these people, Rhimes wrote in her newsletter. Like I had been an Invisible Woman who suddenly materialized in front of them. Poof! There I am. Thin and ready for a chat.

In conclusion, Rhimes reminded her readers that weight is just a number on a scale rather than a window into someones true self. Being thinner doesnt make you a different person, she shared. It just makes you thinner.

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'Grey's Anatomy' Creator Shonda Rhimes Was Treated After Her 100+ Pound Weight Loss: 'Things Got Weird' - Showbiz Cheat Sheet

Physiology

Yoga and the pineal gland: Sadhguru on why yogic sadhana aims first for stability, not ecstasy – Times Now

Yoga and the pineal gland: Sadhguru on why yogic sadhana aims first for stability, not ecstasy  |  Photo Credit: iStock Images

As scientists find better instruments to study the human brain, one thing is becoming clear: there is much more to be known about the mind than we right now know. One aspect of yogic physiology that aligns with modern neurosciences has to do with the pineal gland. This gland was always recognised as being associated with the agna chakra. Today, neuroscientists say that the secretions of the pineal gland control one's moods and experiences.

While medical sciences have made it clear that chemicals can create pleasant and unpleasant experiences within you that are very real for you. Actually, you are causing everything to yourself. The only difference is whether you cause it with or without outside help. If you simply become ecstatic right now, you are creating it without outside help. If you cause the same thing with outside stimulation, it may be the same thing experience-wise, but the end result could damage the system. Unconscious experiences, however big they are, are of no significance for one's growth and transformation.

An aspect of yogic physiology which is totally absent in modern medical sciences is something which I constantly keep on within myself, called the bindu. Bindu means a tiny point. It is a particular spot on the pineal gland. If you touch the bindu, it will release secretions that make you feel ecstatic. But the bindu has another point to it which also has a secretion but is poisonous. If you tip the wrong side of the glass, then poison will spread through the system. It will spread through the system in such a way that, for what looks like simply no reason, you are miserable. A lot of people have done that to themselves. They have become miserable by doing improper things with life.

In yoga, the initial phases of sadhana are aimed at stability, not ecstasy. If ecstasy comes before stability, you are heading for a crash. If ecstasy comes after stability, it is fantastic. The processes of ecstasy were never written down. It is only in the presence of a certain being that those things happen because they are very subjective. In some books on tantra, they have tried to write it down, which I feel is very irresponsible. Suppose you read a book where the first two chapters talk about some simple practices to stabilize yourself and the last five chapters talk about practices to take you to ecstatic levels which one will you do? People will not go for stability, they will go for ecstasy and they will break up.

Never aspire for anything that is not yet in your perception. Just do your sadhana. That is why traditions have always been insisting on trust. If you did not know how a plant grows, if I show you a lump of filth and the beautiful flower and say, These two things are the same... would you believe me? It takes a crazy sense of trust. That is why we do not talk about all those things. Because this cannot be logically worked out. That is why the Guru came into the picture, because a little fixing is needed. Without a little fixing, you will not cross the line.

Sadhguru is a guest contributor. Views expressed are personal.

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Yoga and the pineal gland: Sadhguru on why yogic sadhana aims first for stability, not ecstasy - Times Now

Physiology

Health Care Hero: Imaging workers also on the front lines – Dayton Daily News

The Dayton Daily News is profiling the people who work hard every day to save lives and take care of us. Nominate a Health Care Hero by emailing Rebecca.Mullins@coxinc.com.

Name: Brianne Grizzle

Hometown: I was born and raised in Middletown and now reside in Franklin.

Job Title: CT Technologist

Where do you work: I work at Atrium Medical Center in the Medical Imaging Department

COMPLETE CORONAVIRUS COVERAGE

Describe what your day is like/what you do: As a CT technologist, I am responsible for multiple things. I run the computed tomography scanners that take the X-rays of the patients. I also collect histories from the patients that is pertinent for the exams to relay for the radiologists reading their images. I start IVs, help transfer and position them on the tables for exams in specific ways that can eliminate the dosage of radiation they will receive. Throughout all of these responsibilities, I am doing my best patient care and aiming to take the best pictures in order to help diagnose internal and external injuries, as well as cancers and diseases. I see my purpose as to try to give the most compassion and care for the patients in their most stressful and life threatening times.

What inspired you to get into health care? What inspired me to get into health care was honestly kind of random for me. I had changed majors in college two times previously before choosing radiology. I always knew I had an interest in anatomy and physiology from taking science classes throughout my schooling, but never paid attention to my own thoughts! Now I am so happy I chose a field with many opportunities for growth. I have started as a general X-ray technologist, progressed to a CT technologist, as well as having experience as an MRI technologist.

Health Care Hero: I really love my job

Whats a memorable experience youve had in health care? A memorable experience for me would be really hard to pinpoint because there has been so many with patients and their families. Patients are so grateful to just receive the slightest amount of kindness and caring from medical professionals. By giving someone a warm blanket at the end of my test makes all the difference in trying to make their hospital stay as comfortable as possible.

Health Care Hero: I became a nurse to make a difference

What do you want readers to know about your job right now? What I want readers to know is that all of medical imaging is also in the front line. Great respect definitely go out to the nurses who care for critically ill patients around the clock, but we are often overlooked. Although some of our tests are not long with the patients, we still make an impact on our interactions with them. Our short contacts with patients can become extremely emotional and personal. They are only sent to us because they have a problem such as an broken bone, internal problems, or a mass that they are trying to see if it is cancerous or not. I am the first one to see those images and even if I am able to see a negative outcome for the patient, I have to continue to smile and stay positive until the doctors can relay the results of the tests to them. That is probably the hardest part is continuing to smile for the patients despite their worst nightmares potentially coming true.

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Physiology

Science Interactive Group Partners with BioDigital to Offer Virtual Dissections for Distance-Learning STEM Students in Higher Ed – Business Wire

ENGLEWOOD, Colo.--(BUSINESS WIRE)--Science Interactive Group (SIG) and BioDigital, Inc., two companies at the forefront of the education technology industry, have partnered to provide students and educators with more flexibility in the distance learning space. SIG will embed the BioDigital Human Platform into its lab experiments, allowing online lab science students the option to perform virtual dissections that are supported by custom curriculum.

Partnering with BioDigital enables SIG to offer the option of virtual dissections to our customer base. We believe strongly in offering instructors the benefit of choice when selecting the labs that support their curriculum, said Tim Loomer, CEO of SIG.

The industry leader in distance learning content, lab materials, and education software for higher education institutions, SIG oversees two major providers of online lab science experiments and curricula, Hands-On Labs and eScience Labs. By combining customizable physical lab kits with digital learning tools and a cloud-based educational platform, SIG replicates the tactile lab experience for distance learners, expanding access to STEM education.

BioDigital, whose flagship app has more than four million registered users, provides the world's first 3D human visualization platform. Likened to Google Earth for the human body, the BioDigital Human Platform is an interactive software featuring more than 8,000 individually selectable anatomical structures. Each system is fully segmented, labeled and dissectible for easy configuration to meet any educational need, and the platform uses innovative, cloud-based technology to enable users to view human anatomy and disease in an intuitive visual format. Featuring the most complete, scientifically accurate 3D body ever assembled, BioDigital is utilized by top medical schools and students from over 3000 schools.

By collaborating with BioDigital, SIG is further diversifying its selection of digital learning tools to meet the needs of its expanding market. The ability to choose between physical and virtual dissections in an online course empowers Anatomy and Physiology educators to tailor the distance-learning experience in new ways without sacrificing learning objectives.

BioDigital CEO Frank Sculli noted, With the acceleration to at-home learning, partnering with a forward-thinking organization such as Science Interactive Group that can rapidly integrate our virtual body software to provide thousands of students a richer, more engaging learning experience is an exciting step towards fulfilling our mission of making health and human body more understandable to all people.

About Science Interactive Group

Science Interactive Group encompasses multiple brands, including Hands-On Labs, eScience Labs, StarLab, Science First, BioDigital and Wildco that provide science education solutions to higher education institutions, K-12 institutions, museums, libraries, laboratories, and distributors worldwide. Science Interactive Groups vast assortment of innovative, science-oriented products is designed to provide instructors with interactive, real-world applications that engage students and enhance outcomes. Learn more at ScienceInteractive.com

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Neuroscience

Neuroscience Market Size and Share to See Modest Growth Through 2026 – Surfacing Magazine

CMI published a business research report on Neuroscience Market: Global Industry Analysis, Size, Share, Growth, Trends, and Forecasts 20202026. Neuroscience Market with 150+ market data Tables, Pie Chat, Graphs & Figures spread through Pages and easy to understand detailed analysis. The information is gathered based on modern floats and requests identified with the administrations and items.

The global Neuroscience Market analysis further provides pioneering landscape of market along with market augmentation history and key development involved in the industry. The report also features comprehensive research study for high growth potential industries professional survey with market analysis. Neuroscience Market report helps the companies to understand the market trends and future market prospective,opportunities and articulate the critical business strategies.

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Geographical segmentation of Neuroscience Market involves the regional outlook which further covers United States, China, Europe, Japan, Southeast Asia and Middle East & Africa. This report categorizes the market based on manufacturers, regions, type and application.

Neuroscience Market: Competitive Landscape

Leading players operating in the global Neuroscience Market include:Alpha Omega, Inc., GE Healthcare, Axion Biosystems, Inc., Siemens Healthineers, Blackrock Microsystems LLC, Femtonics Ltd., Intan Technologies, LaVision Biotec GmbH, Mediso Medical Imaging Systems, Neuralynx Inc., NeuroNexus Technologies, Inc., Newport Corporation, Plexon Inc., Noldus Information Technology, Scientifica Ltd., Sutter Instrument Corporation, Thomas Recording GmbH, and Trifoil Imaging Inc.

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Neuroscience

Want to stop the COVID-19 stress meltdown? Train your brain – Fairfield Citizen

(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.)

Laurel Mellin, University of California, San Francisco

(THE CONVERSATION) Lets face it: Were all under stress right now. The uncertainty and constant health threats surrounding the coronavirus pandemic have upended our lives.

We may need two vaccines: one to protect us from the coronavirus and another from the toxic effects of too much stress. Could we train our brains to prevent this stress from becoming lodged in our brains, so we can bounce back faster from stress and even collect a kernel of wisdom from the experience?

Perhaps. Neuroscience research points to the stress-reactive circuits in the emotional brain as a trigger of toxic stress. These circuits are made of neurons that can guide us to respond ineffectively to stress. Once triggered, they unleash a cascade of stress chemicals. Instead of the brain orchestrating a symphony of effective self-regulatory processes and moderation, we have a garage band of dysregulation and extremes, which can cause chronic stress and rising rates of emotional, behavioral, social and physical health problems.

As a health psychology professor, I work on emotional brain training to help people deactivate and rewire the circuits that cause this stress overload.

A new crisis in emotional health

Scientists have been exploring these issues for over a century. Some 100 years ago, the psychoanalyst Sigmund Freud speculated that pathways in the brain caused emotional and behavioral problems. Tom Insel, as director of the National Institutes for Mental Health from 2002 to 2015, called for revolutionizing psychiatry with neuroscience to focus on faulty circuits. The White House BRAIN initiative, launched in 2013, has been busily mapping the brains billions of neurons and their connections to improve understanding of and treatments for a number of disorders.

Then came COVID-19, and suddenly 70% of the U.S. population was identified as moderately to severely distressed in a nationally representative study in April. That was up from 22% just two years earlier.

With a crisis in emotional health upon us, people can benefit from learning to take charge of these stress-reactive circuits and switch off the toxic stress chemical cascade they activate.

Understanding the emotional brain

Most of us arent aware that the neural circuits in our emotional brain the limbic system and subconscious memory systems in whats sometimes referred to as the reptilian brain are the major controllers of our emotional responses in daily life.

When a stimulus arrives in the brain, it activates either stress-resilient circuits, the internal calmers and healers, or stress-reactive circuits, the rabble-rousers that spiral us down into toxic stress.

The brain activates the strongest circuit, which then controls our responses. If it triggers a reactive circuit, that unleashes strong emotions that are challenging to process, especially since stress compromises the functioning of the part of our brains responsible for higher-level thinking and planning. The brain struggles to untangle those stuck emotions, and we become stressed out.

It gets worse. The longer these stress-reactive wires are activated, the more likely they are to activate other stress-reactive wires. One circuit can trigger another and another, which can cause an emotional meltdown of anxiety, numbness, depression and hostility which can overwhelm us for hours or days.

These problematic stress-reactive circuits are encoded during adverse childhood experiences, and later experiences of stress overload. The social isolation from sheltering in place and financial and health uncertainty has strengthened these faulty wires, turning the pandemic crisis into a virtual incubator for making our brains even more reactive and setting us up for a crisis in emotional health.

How to retrain the stressed brain

The stress wires in the emotional brain change through experience-dependent neuroplasticity the brain learns to be resilient by being resilient. It takes becoming stressed, then using emotional techniques to discover and change the unreasonable expectations and unwanted drives stored in that circuit.

Heres one technique: First, briefly complain about whats bothering you. For example: I cant stop beating myself up for all the things I have done wrong. This activates the reactive wire that has encoded a faulty response and makes rewiring possible.

Then, rapidly express emotions. Start with a burst of anger, which decreases stress and keeps the stressed thinking brain from becoming stuck in ruminating, zoning out or overanalyzing. Notice that you can then stay present to your strong, stress-fueled negative emotions, which will then flow rapidly. You can talk yourself through them by finishing phrases like I feel sad that ; I feel afraid that ; or I feel guilty that

That simple emotional release can ease your stress, and the previously unconscious unreasonable expectation encoded in the circuit will appear in your conscious mind. With the wire unlocked, you can then change the expectation into a reasonable one. For example, change I get my safety from being hard on myself to I get my safety from being kind to myself. The unwanted drive that amplifies your stress fades.

In small but important steps to release stress day by day, you train your brain for resilience.

Stress resilience as a social responsibility

Research has shown that emotions transmitted during social dialogue can eventually become large-scale group emotions. We can spread stress to others, and much like secondhand smoke, secondhand stress is becoming a concern.

Ive been surprised in my clinical practice at how quickly individuals link stress with social responsibility. One technology company executive said, Switching off my stress is good for me, keeps me from triggering stress in my family, and its something I do for our country. We are a stressed nation, and I want to be part of the solution.

Stress resilience as a foundation for health

Even though stress overload is a root cause of many health problems, the current model of treating the symptoms of stress rather than rewiring the brains stress response is not sustainable.

At some point, health cares addiction to using medications and procedures to treat the health problems caused by stress will require detox. A new emphasis on training the emotional brain for resiliency may emerge.

If we could reboot our brains for the high-stress times in which we live, just about every aspect of life would improve. Resiliency could provide a needed internal health safety net.

[Insight, in your inbox each day. You can get it with The Conversations email newsletter.]

This article is republished from The Conversation under a Creative Commons license. Read the original article here: https://theconversation.com/want-to-stop-the-covid-19-stress-meltdown-train-your-brain-138785.

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Want to stop the COVID-19 stress meltdown? Train your brain - Fairfield Citizen

Neuroscience

Biohaven Appoints Bob Hugin to its Board of Directors – P&T Community

NEW HAVEN, Conn., June 10, 2020 /PRNewswire/ -- Biohaven Pharmaceutical Holding Company Ltd. (NYSE: BHVN), today announced the appointment of pharmaceutical industry leader Robert J. Hugin to its Board of Directors, effective immediately. Mr. Hugin previously served as the Chairman and Chief Executive Officer of Celgene Corporation where he was instrumental in the strategic growth and global expansion of the company. Celgene was ultimately acquired by Bristol-Myers Squibb in 2019 for a total equity value of approximately $74 billion.

Declan Doogan, M.D., Chairman of Biohaven's Board of Directors, commented, "We are excited to welcome Bob to Biohaven's Board of Directors as we have evolved to a commercial organization and look to the future. Having access to Bob's astute business and financial acumen will help Biohaven achieve our goal of becoming the leading pharmaceutical company focused on neuroscience indications."

Mr. Hugin joined Celgene in 1999 as Chief Financial Officer and served in positions of increasing responsibility during his 19-year tenure with the company, including Executive Chairman, Chief Executive Officer, President and Chief Operating Officer. Until his retirement in 2018, he was the Chairman of the Board of Directors, serving as Executive Chairman from 2016 to 2018. Under his leadership, Celgene saw unprecedented results across all facets of the company and grew by over $30 billion in market capitalization. He is a noted health expert, who advocated for the importance of business development collaborations, innovations in science and improved patient access.

Mr. Hugin stated, "Neuroscience remains one of the most important areas for drug development given the high burden of disability from diseases like Alzheimer's disease, rare neurologic indications, neuropsychiatric disorders and migraine. Biohaven has achieved impressive progress in its portfolio development since becoming a public company and is now successfully commercializing NURTEC ODT, its first product, for migraine. I hope to help transform Biohaven from a development company to a high growth commercial organization with multiple future products addressing large unmet needs in the neuroscience area. I look forward to being part of Biohaven's future success and working closely with Vlad and the rest of the Board."

Vlad Coric, M.D., Chief Executive Officer of Biohaven commented, "Biohaven is honored to welcome Bob to our Board of Directors. His impressive industry experience with high growth companies, strategic insight and passion for improving the lives of patients will be an asset to Biohaven in this time of significant growth as we continue to successfully commercialize our first product and advance our late-stage development portfolio. We are indeed fortunate to have Bob's extraordinary business and financial expertise to help guide Biohaven in advancing novel therapies to patients suffering from disabling neuroscience conditions."

Mr. Hugin also serves as a Director of Chubb Limited, Member of the Board of Trustees of Princeton University and Chair of The Darden School Foundation, University of Virginia. Additionally, Mr. Hugin is currently Chair of the Board of the Garden State Initiative, a nonpartisan research and educational organization focused on economic issues in New Jersey. He is a longstanding Member of the Board of Trustees of Family Promise, a national non-profit network assisting homeless families, and Director of the Parker Institute for Cancer Immunotherapy. Mr. Hugin is past Chairman of the Boards of The Pharmaceutical Research and Manufacturers of America and the Healthcare Institute of NJ. Prior to joining Celgene, Mr. Hugin was a Managing Director with J.P. Morgan & Co. Inc.

Mr. Hugin received an AB degree from Princeton University in 1976 and an MBA from the University of Virginia in 1985. He also served as a United States Marine Corps infantry officer during the intervening period.

About BiohavenBiohavenis a biopharmaceutical company focused on the development and commercialization of innovative best-in-class therapies to improve the lives of patients with debilitating neurological and neuropsychiatric diseases. Biohaven's neuroinnovation portfolio includes FDA-approved NURTEC ODT (rimegepant) for the acute treatment of migraine and a broad pipeline of late-stage product candidates across three distinct mechanistic platforms: CGRP receptor antagonism for the acute and preventive treatment of migraine; glutamate modulation for obsessive-compulsive disorder, Alzheimer's disease, and spinocerebellar ataxia; and myeloperoxidase (MPO) inhibition for multiple system atrophy and amyotrophic lateral sclerosis. For more information, visit http://www.biohavenpharma.com.

Forward-looking StatementThis news release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. The use of certain words, including "believe", "continue", "may", and "will" and similar expressions, are intended to identify forward-looking statements. These forward-looking statements involve substantial risks and uncertainties, including statements that are based on the current expectations and assumptions of Biohaven's management about NURTEC ODT as an acute treatment for patients with migraine. Forward-looking statements include those related to: Biohaven's ability to effectively commercialize NURTEC ODT, delays or problems in the supply or manufacture of NURTEC ODT, complying with applicable U.S.regulatory requirements, the expected timing, commencement and outcomes of Biohaven's planned and ongoing clinical trials, the timing of planned interactions and filings with the FDA, the timing and outcome of expected regulatory filings,the potential commercialization of Biohaven's product candidates, the potential for Biohaven's product candidates to be first in class or best in class therapies and the effectiveness and safety of Biohaven's product candidates. Various important factors could cause actual results or events to differ materially from those that may be expressed or implied by our forward-looking statements. Additional important factors to be considered in connection with forward-looking statements are described in the "Risk Factors" section of Biohaven's Annual Report on Form 10-K filed with the Securities and Exchange Commission on February 26, 2020 and Biohaven's Quarterly Report on Form 10-Q for the quarter ended March 31, 2020 2020 filed with the Securities and Exchange Commission on May 7, 2020. The forward-looking statements are made as of this date and Biohaven does not undertake any obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Biohaven Contact:Vlad Coric, M.D.Chief Executive OfficerVlad.Coric@biohavenpharma.com

Media Contact: Mike Beyer Sam Brown Inc. mikebeyer@sambrown.com 312-961-2502

NURTEC is a trademark of Biohaven Pharmaceutical Holding Company Ltd.

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Neuroscience

Biomedical researchers aren’t using women and men equally as test subjects – Salon

A new study reveals that women continue to beunderrepresented in most biomedical studies, seemingly due to concerns that the variations caused by female hormones will complicate their conclusions. Coming on the heels of a study performed one decade ago that shed light on the problem, it suggests that female biology continues to be inadequately understood within the broader body of scientific knowledge.

The study followed up on a 2010report put together byAnnaliese Beery (who hails from the Departments of Psychology, Biology and Neuroscience at Smith College) and Irving Zucker (who comes from the Departments of Psychology and Integrative Biology and the Helen Wills Neuroscience Institute at University of California in Berkeley). The report found that, between2009 and now, women and other non-human females were shortchanged in biomedical research "often on the assumption that results from males apply to females, or because of concern that hormonal cycles decrease the homogeneity of study populations and confound effects of experimental manipulations." They argued that this compromised understanding of female biology and pointed out that "when only one sex is studied, this should be indicated in article titles, and that funding agencies favor proposals that investigate both sexes and analyze data by sex."

Following up on that study ten years later, Beery and a team from Northwestern University discovered some progress but other areas of disappointment. The number of studies in biological fields to include females jumped from 28 percent to 49 percent over the past decade, but in eight of the nine disciplines included in their report, the proportion of studies that analyzed results based on sex did not improve. Even worse, most of those studied did not provide any explanation for only focusing on one sex or not including sex-based analyses, and the ones that did offer explanations frequently "relied on misconceptions surrounding the hormonal variability of females."

The authors concluded that, while they were encouraged byhow the number of sex-inclusive research studies has gone up in most biological fields over the past decade,"at the same time, close to one third of all research studies that utilized both male and female subjects failed to quantify their sample size by sex."

The authors called for academic publishers to insist that research either include a description of sex or a rationale for focusing on one sex or not including sex-based analyses. They also recommended that funders require grant proposals to include "appropriate sex-based reporting and analyses" and that universities "encourage the consideration of sex as a biological variable" through various institutional and instructional methods.

"There has been a long tradition of viewing men as standard and women as variations to 'the normal,'" Dr. Bandy X. Lee, a forensic psychiatrist at Yale University, told Salon."Obviously, this skews rather than 'uncomplicates'the view of human experience."

She added, "It is similar to the research done on mental disorders. Because most research has been conducted in high-income countries, 80% of the world population has 'atypical' presentations."

The research bias could also speak to broader problems with equal representation overall in STEM fields. According to theAmerican Association of University Women, women only comprise 28 percent of the work force inscience, technology, engineering and math (STEM). This includes comprising only 47.7 percent of biological scientists, 42.5 percent of chemists and materials scientists, 25.8 percent of computer and mathematical occupations and 15.7 percent of engineers and architects.

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Biomedical researchers aren't using women and men equally as test subjects - Salon