Some Chimpanzees Have Tiny Bone in Their Heart | Anatomy, Biology – Sci-News.com

A team of researchers in the UK has discovered that some individuals of the common chimpanzee (Pan troglodytes), particularly those affected by myocardial fibrosis, have a rare small bone called os cordis in their heart.

High-resolution microCT image of the chimpanzees os cordis. Image credit: Moitti et al, doi: 10.1038/s41598-020-66345-7.

The presence of an os cordis is a regular finding in large ruminants such as cattle, ox, water buffalos and sheep. Otters and camels sometimes have this bone too. But this is the first time that the os cordis has been discovered in a great ape.

Cartilage (cartilago cordis) can also be present within the cardiac skeleton of individuals of other animal species such as horses, pigs, dogs, cats, mice, rats, snakes, white rhinoceros and Syrian hamsters.

Although the exact localization, size and number of the os cordis varies, in all species it lies within a band of fibrous tissue called trigonum fibrosum.

Its function is unclear but it is believed to serve as a pivot and anchoring support for the heart valves.

The discovery of a new bone in a new species is a rare event, especially in chimps which have such similar anatomy to people, said studys senior author Dr. Catrin Rutland, a researcher in the School of Veterinary Medicine and Science at the University of Nottingham.

It raises the question as to whether some people could have an os cordis too.

Dr. Rutland and colleagues compared the structure and morphology of 16 hearts from chimpanzees which were either healthy or affected by myocardial fibrosis, a type of heart disease found in chimps and people.

To study the organs, the researchers used X-ray microtomography (microCT), a non-destructive X-ray imaging technique that produces 3D images from 2D trans-axial projections.

They found the os cordis bones, measuring a few millimeters in size, and cartilago cordis in four hearts. Their presence was not associated with age nor with sex.

Looking for ways to help chimps with heart disease is essential, said first author Dr. Sophie Moitti, from the School of Veterinary Medicine and Science at the University of Nottingham and Twycross Zoo.

Understanding what is happening to their hearts helps us manage their health.

This research has brought together researchers and veterinary professionals, working on a common aim to advance chimpanzee health and conservation, Dr. Rutland said.

The discovery is described in a paper published in the journal Scientific Reports.

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S. Moitti et al. 2020. Discovery of os cordis in the cardiac skeleton of chimpanzees (Pan troglodytes). Sci Rep 10, 9417; doi: 10.1038/s41598-020-66345-7

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Moving Forward: The Anatomy of Racism in Our Everyday Lives – Blue Virginia

by Fairfax County School Board member Karen Keys-Gamarra

In the past few weeks, many people, especially African Americans, have had to reconcile what they have seen in witnessing the murder of George Floyd and that of their own experience. I am no exception.

I have lived long enough to wipe away many tears of frustration in moments that simply did not recognize or appreciate our humanity. Whether it was in my new elementary school, where I became the first black girl in the class, and the teachers stood behind me in amazement because they did not expect me to exhibit logical thought. Or, as a mother who fiercely protected her kids. Or in every workplace I have encountered. The root was always the same: racism.

Racism, or the R word, can become a hideous tool that acknowledges a structure kept in place to maintain control and dominance of another. I have seen both the masterful and the novice attempt to use R as a weapon to steer the actions of others and/or to demean me, or sometimes both. Whether I was walking my sons bike home in my neighborhood so that he could stay to have a sleep over; or, conducting a campaign during an election; or, working to protect children; or in the Board rooms the truly crafty find this tool handy.

I dont always speak about it, but I do see it and I respond when I believe the action I am experiencing is so cruel that it resembles that of an overseer who demands compliance. I say what I have to and I work in difficult situations because I must. This is not an accusation of every person I have met, but the widespread presence of racism is a stain to this democracy and to the life experience of many in my community. I have been patient and collaborative. I have had hard discussions with folks, some fruitful and some not. Now it is time to simply diagram what a life in a society where racism has not been eradicated really looks like. It is not all inclusive, but a conversation starter. We need to face R and we need to take affirmative steps to do something about it.

I, like many others, have grown intolerant of the structures founded on racismthat belief that allows us to treat others differently, to feel superior or to dominate and oppress another with a self-righteous justification. The R can be comprised of aggressive or passive aggressive acts, even micro-aggressive acts, as R comes in many forms. For some, it is revealed in overt murderous acts or for the more subtle, manipulative acts that use code words that allude to race without ever having to mention the word. For the truly sophisticated, it shows up in delay tactics, calls for comfort to naysayers, or an attempt to find the right person for the job. Oh, and my favorite, lets pit blacks in this workspace against one another because after all, we only need one.

My intolerance is a response to a system of actions with a 400-plus year history in this nation. The systems of Racism where installed when a few crafty businessman acted on the belief that human trafficking, and receiving work without compensation to the slave, could be a profitable business. Slavery doesnt belong to Blacks, as it has been a worldwide practice. While slavery has been abolished in the U.S., its hideous remnants remain. So here you will find a few more characteristics and scenarios that help identify the trappings of this diabolical weapon.

More Details on What R Looks like

Racism is always something that is expected to create a structure of power. It is often practiced in secret and sometimes those who witness it become complicit. For some, there is an inherent need to be a part of the powerful and not the powerless. For other witnesses, they can become complicit by being unaware of past practices or a culture. Racism is always a form of bullying, because it is a way to whip another person(s) into submission. Racism can also occur amongst those who genuinely want to do the right thing, but are less familiar with this tactic. It is often masked as a pending question, where theres an effort to achieve the right fit or find the best person for the job. The word racism itself is rarely used in these situations.

When It Appears

I was in first grade when I realized that racism would be a part of the tapestry of my life. I was playing in front of my new house with my brother. A little girl stood at the end of her driveway and just looked at me and my brother. I invited her to join us. Her response was, my daddy doesnt allow me to play with people like you. I kept playing; after all, I was with my brother, she was alone. Later, I learned that she was the daughter of a police officer. My mother, who was masterful in being a strong woman who determined her own path, told me that some people have a problem, but to never let their problem become your problem. I still live by those words today. She also raised me with what some might call good home training. I learned that I would be judged, but not to internalize, that I must keep my composure, to speak enough words to get my point across and to never waste energy on those who create distractions and eat up my time. All actions do not require a reaction but I would learn the difference. But back to that intolerance

Racism Always Expects a Culture of Tolerance

In my mothers generation, society expected a well-behaved Negro. This term referred to the dignified person who did not crack under pressure. The well-behaved Negro protested with MLK and didnt fight back; sat at the counter while being spat upon; went to the work place worked hard and was passed over for promotions; and endured code language that demeaned the quality of their work and/or pitted blacks against one another for the same job. After all, we only need one black person to look like its not R, right? It is the culture of the well-behaved Negro that taught black parents to teach their kids to obey the police, to keep their hands on the wheel, to speak politelythese are all the lessons of the well-behaved Negro. Emmett Till was killed because he was accused of violating the silent code of the well-behaved Negro.

After the Civil War, the KKK worked across this nation sowing the seeds of fear through threat, lynchings and other forms of violence to enforce the code of the well-behaved Negro. This code also tells Black folk to stay in their place or face penalty that most times was not addressed by law enforcement. In 1921, we saw the burning of Black Wall Street in Tulsa, Oklahoma part of a trend in several cities where countless murders occurred because those folks violated the code. Implicitly, the code require submission of Black folk to the dominant race and in police encounters today, it says that your life can end in a millisecond. Amy Cooper of Central Park relied upon the code when she called the police and falsely accused a black man of threatening her. What made her disregard the fact that she was being filmed? Yes, R causes blindness, too because Amy relied upon and expected the police to enforce the code of the well-behaved Negro. While poor Amy read law enforcement right, as she has faced no legal ramifications for her act, she underestimated the social tolerance for her demand and so her name will forever be used as an example of a woman who expected privilege and used racism to achieve her goal.

What this Intolerance means.

With the demonstrations of protest all around us, the message is clear: We will not be your well-behaved Negro. Whether its law enforcement or the Board room, the time for sucking it up and watching the effects of R, even if it is quietly implemented to achieve a desired goal those times are over. I have felt this indignation in me. I have seen it in my friends, whether black, white, Hispanic or other races or creeds. The folks we see in the streets are not just the recipients of these heinous acts but those who have grown intolerant of them as well.

This intolerance also means that we must take affirmative steps to eradicate the effects of R in every level of our lives.

What we must Understand

What we must Do

Conclusion

I want my friends to know that I appreciate all the cards, notes and words of assurance. I know that we have many allies and people who want to do the right thing. But the desire to do the right thing isnt enough. We must collectively meet wherever we are and ask, what can I do? How can I learn and how can I assist in implementation of better procedures and policies? How can I listen better today? How can we weed out code words in conversation and make sure that we are never complicit in the divisions that racism creates. This is our burden, this is our work. Lets tear these barriers down, together!

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Moving Forward: The Anatomy of Racism in Our Everyday Lives - Blue Virginia

The anatomy of a media manhunt – Spiked

Having worked in journalism and been a member of parliament and a minister in a European country for many years, I find many aspects of the Dominic Cummings affair eerily familiar.

During my time as a journalist, I was often surprised by how openly some of the editors and reporters discussed how to get someone. In daily meetings they would debate which pundits might be most critical of the person in question. This was before social media provided an endless source of condemnations to choose from and members of the public started competing to denounce heretics.

Working in journalism, it soon became clear to me that coverage of events was greatly influenced by preconceptions about the people involved. This was decades ago. But now, more than ever, the things that people do and say are judged not by the content or nature of what is said and done, but by who says or does them.

One of the greatest achievements of Western civilisation was reaching the conclusion that all individuals should have the same rights. The modern zeitgeist seeks to turn this principle on its head.

In effect, we now have a hierarchy of personal rights based on which group individuals are assigned to by the high priests of identitarianism. Very near the bottom of that hierarchy sits Dominic Cummings highest among his sins in the eyes of intersectionalists is that he is blamed for the UKs departure from the EU.

This cultural establishment is hostile towards challenges to its authority. People who are seen as a threat to the ruling order must be quelled, and the opportunity to do so is eagerly awaited.

What turned out to be the long-awaited excuse for doing away with Dominic Cummings? He drove with his family from London to Durham to self-isolate and protect his child. How has British society come to this?

I now know that Durham is 260 miles from London, and feel confident that I could drive there without the aid of a map or GPS, having heard the route described ad nauseam. The path that Cummings critics have taken is, however, even more familiar to me than the route from London to Durham.

Cummings was known for his criticism of the elites. So he was presented as an elitist who thought there was one set of rules for him and another for everyone else. This was to have the added effect of getting everyone else to unite against the offender. Hence the elites attacking Cummings because of who he is did so by claiming he was behaving as an elitist. The irony was apparently lost on the intersectionalists.

The pursuit of Cummings followed a familiar script.

With the perpetrators offence established, the hunters start reporting every criticism of their prey. Modern social media provides an inexhaustible well of such criticism, ranging from accounts of people who believe they may have witnessed the perpetrator committing other offences to gifs and other jokes from the internet (allowing for headlines such as This video mocking Cummings trip has gone viral). The objective here is to give the impression that more or less everyone is of the same opinion. Differing views get almost no attention, except when someone comes to the defence of the accused in a manner that is easily ridiculed.

Next, the public gets to hear the opinions of experts. Anyone willing to use their particular field of work or study to aid in the persecution are lifted to the level of being an authority on the subject, regardless of whether the person in question is an activist with an axe to grind. One expert after another explains how much harm has been caused by the perpetrator.

This is made particularly effortless by use of the accusation angle, whereby accusations are made that allow for headlines like X has been accused of Y or It has been claimed that. Never mind innocent until proven guilty. The accusation is handled almost as a statement of fact.

Before long, people seeking attention, or seeking to contrast their own perceived virtue with the shortcomings of the delinquent, come running after the bandwagon, trying to climb on to it. Nowadays, this unfortunately usually includes clergymen with no recollection of the ideas of forgiveness or avoiding judgement.

All this provides for a continuous loop of media coverage. One outlet tells the public that the bishop of Whereverburry is critical of the accused. Another outlet picks this up, thus lending the story increased significance before adding that now the bishop of Somewhereinlsington is even more outraged. In essence, character assassinations are a serial, where every step is based on the previous groundwork.

If the prey is able to walk on and prove that the initial accusations were unfounded, the hunters simply change the accusations. The aim is not to get to the truth, but to catch the prey (win the game by forcing a resignation or exclusion). Initially, Cummings was accused of breaking the law. When that didnt seem to be the case he was accused of having broken the rules, and then finally the spirit of the rules.

A classic ploy, much used by totalitarian regimes, is to constantly ask the subject to apologise. Asking for an apology has the appearance of being a reasonable request. Do you feel no regret, are you really not willing to apologise to the people who have been making sacrifices? Refusing to apologise makes the accused seem condescending. But, as soon as the person apologises, it is interpreted as an admission of guilt.

Attempts to procure an apology are usually followed by accusations of a lack of humility. If only he had shown more humility, people might have been able to show more understanding. Balderdash! The accusers are not seeking humility, they are seeking degradation.

Once it has been established that the nation is outraged and wants the accused to take responsibility, an easy next step is to claim that the person in question is harming the national interest. But if the media really thought that Dominic Cummings harmed the national interest by going for a drive, and thus setting a dangerous example, why were they constantly telling people that his behaviour would be seen as an invitation to break the rules? Who was really encouraging rule-breaking here the man who went for a drive weeks ago or those who were constantly telling people it provides them with an alibi to do as they please?

According to Sky News Beth Rigby, Ministers worry that [the impact of Cummings drive to Durham] could mean the R number begins to rise, bringing in turn more cases, more deaths and even a second wave; the economic, social and public health consequences of which are unconscionable. There we have it: Cummings previously unknown drive to Durham might cause untold death and destruction.

Why do the media behave in this way? There are several reasons. These stories create excitement and competition, where contenders see the situation as a chance to prove themselves. Meanwhile, criticising other journalists or offering another perspective risks undermining the work of colleagues, or even being branded an apologist. It is easier to convince yourself that you are on a worthy crusade on behalf of the people.

Whats more, many journalists now feel that their role is more important than just revealing the facts. They feel they must influence what happens, not just report it. Thus gaining a position of influence means you must use that influence to affect the agenda. That makes the competition even more important. It isnt just a sport, it is a fight for social justice. And when the target is already seen as an enemy of those values, it provides a very strong extra incentive.

The media crusaders also tend to become completely blind to how it all looks to people outside the bubble. This is equally true of politics. Those within the political bubble have great difficulty comprehending how what they do looks to outsiders. A good politician will try to step outside the bubble to get a better view, but that can be very difficult.

If the accused is involved in politics, an essential part of the process is to cause anxiety within his or her party, in order to create pressure from party members to sacrifice the targeted individual. Internal friction is a natural feature of most political parties, so this usually yields quick results.

If those with an axe to grind, or hoping for promotion, do not jump at the opportunity, the hunters will try to get the partys rank and file to influence them. Party members are often sensitive to criticism, so the constant reports about opinion polls and the national will are often enough to do the trick in many cases. Once again, todays journalists dont even need to call anyone up. Ploughing through social media will provide all the criticism they need.

In a parliamentary group of 365 people (as in the case of the British Conservatives), you will always find someone willing to criticise the accused in order to signal their own virtue. Then the counting begins, in order to increase the pressure on the party leader: This evening we have learned that three more MPs have joined in criticising their own party leader.

To help with the tallying, stories are told about how MPs have been inundated with angry letters from constituents. This is despite the fact that these constituents may be people who would never vote for said MP, and may well loathe his party but that is not part of the narrative.

After all this, why did Boris Johnson not give up and get rid of the problem by getting rid of Dominic Cummings? The hunters will tell you that he is so reliant on Cummings that he feels helpless without him. A likelier explanation is that the prime minister realised what was going on, and knew that by giving in he would be confirming that he can be broken through such methods, making it all but certain that he would face many more such scenarios, all with the end goal of making him the eventual target.

Still, there will be many more fights like this one, and in most cases the hunters and prey will come from the groups dictated by modern identity politics.

People will also continue to complain that modern politics lacks leadership. This is true, but we should ask why this is the case. I fear it has a lot to do with stories such as the Dominic Cummings affair, and so many others before it. For most modern politicians, their main objective is to get through each day without doing something that might be considered controversial. But a decision that requires leadership will almost by definition be controversial.

All this results in weaker politics, more focused on personal attacks than a rigorous debate about the fundamental issues facing our societies. While politicians and much of the media are preoccupied with defaming the character of their competitors, the unelected establishment runs the country. The end result is a weaker democracy where the voters are increasingly disenfranchised. They no longer have the opportunity to influence how the country is run and are reduced to choosing a symbolic representative, determined only to get through a term without doing anything even mildly controversial, interesting or useful.

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5 ‘Grey’s Anatomy’ Episodes That Changed the Shondaland Series Forever – Showbiz Cheat Sheet

Greys Anatomy has been on for 16 seasons and counting. The popular Shondaland series has over 350 episodes with no plans of slowing down anytime soon. So naturally, things have shifted over the past 15 years, from cast changes to the overall tone of the medical drama. And while we patiently wait for the 17th season to arrive on ABC, weve gathered a few iconic Greys Anatomy episodes that truly changed the direction of the series forever.

RELATED: Greys Anatomy: Proof That the Show May End in 2021

The two-part shooting episode in Greys Anatomy Season 6 is the most devastating piece of work Shondaland has put out to date. A grieving widower, Gary Clark (Michael ONeill), arrives at Seattle Grace Mercy West Hospital with a gun to kill Derek Shepherd (Patrick Dempsey) and Richard Webber (James Pickens Jr.). But in the end, there were significantly more casualties than the shooter originally planned.

Gary murdered Reed Adamson (Nora Zehetner) and Charles Percy (Robert Baker). He wounded Alex Karev (Justin Chambers), Owen Hunt (Kevin McKidd), and Derek.

Meanwhile, Meredith Grey (Ellen Pompeo) revealed she was pregnant with Dereks baby. But the stress from the shooting caused her to miscarry. Then after speaking with Richard, Gary shot himself, ending the stress-filled episode with yet another tragedy.

Following the Greys Anatomy episode, the characters were never quite the same. There was a dark cloud looming over everyone involved when the Shondaland series returned. And much of the seventh season dealt with the repercussions of the shooting.

RELATED: 4 Greys Anatomy Couples That Deserved to Be Endgame

The Greys Anatomy Season 8 finale was one of the most pivotal moments in the shows history. And its honestly shocking to see how many characters were affected by the tragic accident.

For one, Arizona Robbins (Jessica Capshaw) lost her leg. This was a turning point for the character, especially since Callie Torres (Sara Ramirez) was the one who made the call. Eventually, this led to a great deal of resentment and divorce.

The plane crash also resulted in the deaths of Mark Sloan (Eric Dane) and Lexie Grey (Chyler Leigh). This left Derek without his best friend. Callie and Arizona Robbins also lost the father of Sofia. Meanwhile, Meredith lost her sister.

The surviving members of the plane crash Derek, Meredith, Arizona, and Cristina Yang (Sandra Oh) ended up suing the hospital before buying it, along with Callie, Richard, and Catherine Avery (Debbie Allen). Then, as a result, the doctors renamed the hospital to Grey Sloan Memorial, closing the chapter while celebrating the lives of Mark and Lexie.

RELATED: 3 Greys Anatomy Deaths We Will Never Get Over

For the first few seasons of Greys Anatomy, viewers fell in love with the dynamic between MAGIC Meredith, Alex, George OMalley (T.R. Knight), Izzie Stevens (Katherine Heigl), and Cristina. However, the fifth season finale broke the fandoms heart.

In Now or Never, George got hit by a bus and died. This was the first major character death, breaking up the core group of interns. Meanwhile, the episode also introduced the descent of Izzies character and she left midway through the sixth season.

RELATED: Greys Anatomy: 3 Meredith and Cristina Moments That Will Make You Miss Their Friendship

Speaking of core exits on Greys Anatomy, it would be impossible to ignore Cristinas departure from the series. The character left for a new opportunity in Switzerland, courtesy of Preston Burke (Isaiah Washington). However, Cristinas exit meant Meredith would lose her person and the Twisted Sisters would be separated.

Of course, we still receive references to Cristina on Greys Anatomy today. Nonetheless, the friendship between Meredith and Cristina was a big part of the show. And when the show took the dynamic away, it left a gap that was never truly filled. But even so, it seemed Cristinas final remarks moved Merediths character forward. And Meredith finally started seeing herself as the sun.

RELATED: Greys Anatomy: Who is the Attending Doctor That Killed Derek McDreamy Shepherd?

An epic romance doesnt mean there will be a happy ending, especially on Greys Anatomy. From the candle house to the post-it note wedding, fans thought Meredith and Derek would be endgame. But it was far from that.

Throughout the 11th season, Meredith and Derek faced a few challenges, as the neurosurgeon received an important job in Washington D.C. Derek was absent through most of the season. And the couple seemed to be headed for divorce. But luckily, MerDer realized what was important. So Derek decided he would return to Seattle.

Nevertheless, Derek was struck by a semi-truck in How to Save a Life. He ended up at a hospital without the proper resources and doctors. Then Derek was declared brain dead and Meredith took him off life-support.

The repercussions of Dereks death echoed throughout Greys Anatomy for seasons to come. Following the episode, the ABC drama became much darker as Meredith dealt with her grief. But now, its been a few years since Derek died and the Shondaland drama has become more light-hearted in recent seasons. So as they say, time heals all wounds.

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Lenox Hill Review: This Is the Reality TV Version of Greys AnatomyAnd It Will Move You – Glamour

If you've exhausted every available episode of Grey's Anatomy, I have your next marathon right here: Lenox Hill, Netflix's new reality series about real doctors, real hospitals, and some very real drama. It takes place in one hospital, specificallythe Lenox Hill Hospital on Manhattan's Upper East Side (with a branch in Greenwich Village)and spotlights four doctors: two brain surgeons (John Boockvar and David Langer), an ob-gyn resident (Amanda Little-Richardson), and an emergency room physician (Mirtha Macri). The conceit of the show is simple but effective: Watch a day in the life of each of these doctors. We learn the specifics of their cases, see their breakthroughs, and witness private phone calls with their partners and children. Mirtha and Amanda were both pregnant at the time of shooting, so we see those storylines, as well.

That boiler plate is pretty similar to Grey's Anatomy, when you think about it. Both shows spotlight doctors doing incredible work, but there's nothing clinical about either of them. The emotional notes on Grey's Anatomy are just as potent as the medical ones, if not more so, and that's the case for Lenox Hill too. Seeing Amanda having a difficult conversation with her ob-gyn about her own pregnancy is just as moving as watching her help deliver a baby. Likewise, catching a glimpse of John planning a family party on the phone with his wife is equally as thrilling as seeing him make breakthroughs in cancer research. I may be alone on that onebut doctors, in my opinion, are the closest things to superheroes that we have. And seeing a superhero talk about a Sunday barbecue feels bizarre.

"This series humanizes physicians and allows people to see the hard work, dedication, passion, and sacrifice we give to our jobsnot for money, but because we genuinely want to help people," Dr. Little-Richardson said in a statement.

Lenox Hill does an excellent job at capturing just how superhero-y these doctors really are. Whether it's Dr. Langer performing a complicated tumor removal on a 28-year-old patient or Dr. Macri seeing dozens of E.R. patients in one night on very little sleep, the weight of their work is not lost on viewers. For medical-philes alone, this show is going to tick a lot of boxes. You get up close and personal with a lot of medical jargon and graphic imagery. (That being said: Squeamish people, beware.)

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Lenox Hill Review: This Is the Reality TV Version of Greys AnatomyAnd It Will Move You - Glamour

Grey’s Anatomy: 5 Of George’s Sweetest Moments (& 5 Most Heartbreaking) – Screen Rant

George O'Malley quickly became a fan-favorite character on the hit primetime medical drama,Grey's Anatomy. George arrived at Seattle Grace Hospital as an intern with Meredith, Cristina, Izzie, and Alex. One of the original five series regulars, George's storylines were full of laughs, heartaches, and discoveries.

RELATED: Grey's Anatomy: 10 George O'Malley Quotes That Will Make You Miss Him Even More

Over the course of George's five seasons on the show, fans saw the character learn and grown and everyone fell in love with him, making his untimely death at the end of season five completely devastating. Looking back on George's time onGrey's Anatomy, there are a lot of wonderful moments and a lot that have viewers reaching for the tissues.

Miranda Bailey, the resident in charge of George and his other intern friends, is pregnant in the second season of the show. Halfway through the season, Miranda goes into labor and it's George who is by her side during her delivery because Miranda's husband is in another OR having emergency surgery.

George stays with Miranda the entire time, supporting her physically and emotionally. It means so much to Miranda, that she gives her son the middle name, "George".

George has always harbored unrequited feelings for Meredith, so when Meredith and Derek end their relationship once Derek's wife, Addison comes to Seattle, George is there for his friend/love interest.

RELATED: Derek & Meredith: 10 Most Heartbreaking Times Characters Cheated On TV

Unfortunately, a line gets crossed and George and Meredith end up sleeping together, which Meredith instantly regrets and bursts into tears in bed with George. George is understandably hurt by the events and feels terrible about the effects this one action had on his and Meredith's friendship.

When Meredith puts out an ad wanting roommates for the big house she's inherited from her mother, George and Izzie move in. Quickly, these three become more like family, and George supports, loves, and protects his friends to the fullest.

In one episode, Izzie comes home after a terrible first date with Alex, and Meredith is upset over another thing Derek did, and they both turn to George for help at the same time. George makes room on his bed for his two best friends and lets them vent.

In season three, George, Meredith, Izzie, and Alex have to take their intern exams. If they pass, they can move on to becoming residents. If they don't pass, they have to re-do their intern year.

RELATED: Grey's Anatomy: The 5 Tallest (& 5 Shortest) Actors In The Cast

Everyone passes except for George, who gets left behind to repeat his internship while his friends move on to being residents with their own interns. George starts to feel left out of his original friend group because he is no longer working with them, but for them.

Izzie falls in love with a patient, Denny Duquette, who needs a heart transplant or he will die. In a desperate attempt to get Denny a new heart, Izzie cuts hisLVAD wire to try to move him up on the donor list.

The plan doesn't work and Denny dies, leaving Izzie devastated. George is Izzie's best friend and everyone looks to him after Denny dies to better understand how they can help Izzie. In a sweet moment, George tells Izzie that he would have given Denny his heart if he could.

When a new batch of interns come to Seattle Grace, George and his friends have a new cast of characters to figure out, including Lexie Grey, Meredith's half-sister. George has to stay back a year after failing his intern exams and he quickly makes friends with Lexie.

RELATED: Grey's Anatomy: 5 Of The Most Annoying Things Lexie Ever Did (& 5 Sweetest)

Unbeknownst to George, Lexie develops feelings for him and grows increasingly more frustrated as time passes and George still seems to be completely clueless to Lexie's emotions.

After George marries Callie on a whim, the two newlyweds struggle with merging their lives and their friend groups. Callie seems increasingly jealous and uncomfortable with the amount of time George spends with Izzie and Meredith and tends to belittle the residents, including Cristina.

During an increasingly heated debate, George finally stands up to Callie and explains that Meredith, Izzie, and Cristina are his family and that she must love them if she loves him.

George and Callie rushed into their marriage and clearly weren't ready for it. That fact becomes even more clear when George cheats on Callie with his best friend, Izzie. George finally gets up the nerve to tell Callie about the affair, expecting Callie to want to end the marriage, but she doesn't.

RELATED: Grey's Anatomy: Why Meredith And Izzie Aren't Real Friends

Instead, Callie tells George they can work through it, which makes the situation even more heartbreaking because it's clear that's not what George wants.

Izzie gets diagnosed with a brain tumor in season five and her prognosis is not good. Alex and Izzie decide to get married on the day that should have been Derek and Meredith's wedding. Meredith realizes that Izzie has been helping her plan Izzie's dream wedding, so she gives the wedding and the day to Izzie so she can marry Alex.

George is the person who walks Izzie down the aisle, which is perfect considering their history and the unconditional, platonic love they have for one another.

At the end of season five, George has enlisted in the army. On the day he enlists, he dives in front of a bus to save a stranger's life. This accident causes George to lose his own life, despite the doctors at Seattle Grace's best efforts.

They don't even realize the patient their treating is George initially because his face has been disfigured by the accident. Meredith realizes John Doe is George after he spells out the number "0-0-7" on Meredith's hand.

NEXT: Grey's Anatomy: 10 Of Meredith's Scariest Surgeries

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Amelia Brantley is a writer and actor based in Los Angeles, California. Her love for film, television, and theater drove her to pursue her dreams at a young age. She has a Bachelor's Degree in Acting from The American Music and Dramatic Academy and constantly auditions/works in the industry. In addition to writing for ScreenRant, Amelia also blogs, on her own blog, as well as for other entertainment industry online resources. If she isn't writing or self-taping, she's most likely cuddling with her dog, Warner George.

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Grey's Anatomy: 5 Of George's Sweetest Moments (& 5 Most Heartbreaking) - Screen Rant

10 Movies To Watch If You Love Grey’s Anatomy | ScreenRant – Screen Rant

Grey's Anatomy premiered on the ABC network as a mid-season replacement in March of 2005. It has gone on to become the longest-running medical drama in television history. This show has stood the test of time and delivered compelling and important storylines to its ever-growing fan base for the last 16 seasons and it doesn't appear to be slowing down anytime soon.

RELATED: Grey's Anatomy: Meredith's 5 Best Outfits (& 5 Worst)

All of the last 15 years of episodes are available to stream on Netflix, which should hold viewers over until the 17th season premiere, but if it doesn't, here are some films that may help get you to get your fix!

One of the reasons fans fell in love with this series from the very beginning was Dr. Derek Shepherd, or "McDreamy," played by Patrick Dempsey.

Dempsey had worked in Hollywood for decades before starring on this series, but it was this series that elevated him into heartthrob, household name status. For fans who miss the McDreamy charm,Enchanted is a great film to watch because Dempsey plays an actual Prince Charming.

Grey's Anatomy is known for its tear-jerking storylines and heartfelt dialogue. It's a show also known for its suspense and drama.

RELATED: The 10 Best Denzel Washington Movies, According To IMDb

If you're looking for something that will leave you on the edge of your seat just as much as it will have you reaching for the tissues, thenJohn Q, starring Denzel Washington and directed by Nick Cassavetes, is a great option for movie night.

Everyone knows that Derek and Meredith were meant to be, just like Mark and Lexie were meant to be, and Izzie and Denny were meant to be, which is why the episode where Derek dies, and the one where Lexie dies, and the one where Denny dies, are so devastating for fans to watch.

If you're looking for a story that is equal parts love and tragedy, this film, about a husband who loses his wife and then falls for the woman who receives his late wife's heart after her death, is a must-see.

Some of the best episodes of the hit medical drama are the ones where doctors manage to pull off a medical miracle and save a patient's life, and even they're amazed that the person lived, like when Meredith drowns and all of the doctors work to bring her back to life or when Derek and Meredith have their first success during their clinical trial.

RELATED: Grey's Anatomy: 10 Things You Never Noticed About The First Episode

If you need an uplifting story full of miracles,Breakthrough, starring Chrissy Metz should be on your list.

The way the characters onGrey's fall in love and support one another through good times and bad is so encouraging and inspiring for viewers to watch week after week. Watching Cristina and Owen navigate their relationship through their individual traumas or seeing Meredith love again after Derek leaves us all with a lot of hope.

The filmLove and Other Drugs,starring Anne Hathaway and Jake Gyllenhaal, has a lot of these themes in it and shares the "love conquers all" message.

Arizona Robbins is one of the hottest doctors on television, not only in appearance, but also because of the fact she's a pediatrician and nothing is more attractive than a hot doctor who loves children. If you share this sentiment,The Wedding Planner is probably already one of your favorite movies.

RELATED: Matthew McConaughey Rom-Com Roles, Ranked (According To Rotten Tomatoes)

In this film, Matthew McConaughey plays a pediatrician who falls for Jennifer Lopez's character, Mary. This film also features a young Justin Chambers as another love interest for Mary.

Katherine Heigl was a staple in the first six seasons ofGrey's Anatomy and for fans who miss Izzie Stevens, there are luckily a lot of movies starring Heigl in which she brings some of the same quirks, charm, and sweetness of her Grey's character.

One of Heigl's best rom-com roles is as Holly inLife As We Know It, also starring Josh Duhamel as Eric. Holly and Eric are put in charge of caring for their best friends' baby after the couple dies in a car accident. There are some great laughs and cries in this one.

This late 90s, semi-autobiographical feature starring Robin Williams is a tear-jerker. It tells the story of Patch Adams, a doctor struggling with mental illness who decides to open a clinic to help uninsured and less fortunate patients.

RELATED: 10 Things We Learned From Robin Williams' Movies

Patch Adams believes that laughter is the best medicine, so for fans who tune in to watchGrey's week after week to feel good and inspired, this movie should have the same effect.

Ellen Pompeo has been pretty open with her struggles trying to "make it" in Hollywood. Pompeo was 35 when she booked the role of Meredith Grey, which for an actress in Hollywood, means her success came much later than most of her colleagues.

If you'd like to see Ellen Pompeo on her road to success, watchOld School. In this comedy, Pompeo plays Nicole, a love interest for Luke Wilson's character, Mitch.

If you're a fan of Cristina Yang and Addison Shepherd, you need to watchUnder the Tuscan Sun, starring Diane Lane. Sandra Oh and Kate Walsh play a couple expecting their first baby in the film. These two actresses have a lot of chemistry, which makes viewers wonder why they didn't share the screen more during their time onGrey's Anatomy.

In this film, Walsh plays a doctor, as well, making us all wonder if this movie is actually set in some alternateGrey'sreality.

NEXT: Grey's Anatomy: 5 Of McDreamy's Most Romantic Quotes (& 5 From McSteamy)

Next The 10 Best MCU Movies (According To Metacritic)

Amelia Brantley is a writer and actor based in Los Angeles, California. Her love for film, television, and theater drove her to pursue her dreams at a young age. She has a Bachelor's Degree in Acting from The American Music and Dramatic Academy and constantly auditions/works in the industry. In addition to writing for ScreenRant, Amelia also blogs, on her own blog, as well as for other entertainment industry online resources. If she isn't writing or self-taping, she's most likely cuddling with her dog, Warner George.

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10 Movies To Watch If You Love Grey's Anatomy | ScreenRant - Screen Rant

Greys Anatomy: 10 Ways Meredith Got Worse And Worse – Screen Rant

Meredith Grey is the central character of Grey's Anatomy, but as the show has continued, she has seriously gone downhill.

Grey's Anatomyhas done it all over 16 seasons, from wild surgeries to epic love stories to friendships ending. At the heart of it all is Meredith Grey (Ellen Pompeo), the super ambitious surgeon who is following her mother's path even if she wouldn't admit it. Meredith has been through it all, from losing a husband to raising kids to dealing withcountless major changes at the hospital whereshe works.

RELATED:Grey's Anatomy: 10 Best Seasons, Ranked By The Rotten Tomatoes Audience Score

Even though Meredith is the main character on the dramatic series, she has made a lot of mistakes and has a lot of moments when she doesn't seem very well-drawn.Read on to find out 10 ways that Meredith's character got worse on this popular hospital drama.

One of the best aspects ofGrey's Anatomyis the friendship between Cristina Yang (Sandra Oh) and Meredith. But since Cristina left for Switzerland in season 10, Meredith hasn't had the same kind of connection with anyone else.

RELATED:5 Reasons Why ER Is The Definitive Medical Drama (& 5 Why It's Grey's Anatomy)

One way that Meredith has gotten worse over the course of the show is in terms of her friendships. They just aren't as well-developed. Even when Meredith hangs out with Alex Karev (Justin Chambers), it doesn't feel the same as when she and Cristina would talk about deep subjects or dance it out.

DerekShepherd (Patrick Dempsey) was always pretty good for Meredith. He convinced her that there was a life outside work, he started a family with her, and he loved her.

But since Derek died, it feels like Meredith's character development has been at a plateau. She has kept all of her same tendencies, such as being closed off from new people, wanting to do everything on her own, and being too tough.

Even if the biggest fans ofGrey's Anatomyhad to list Meredith's personality traits, it would be hard not to just say "she's totally miserable" and call it a day.

Meredithspends a lot of time complaining or moping around, and she isn't very kind to the people around her. This feels like a flaw with her character development. Whenever she's in a good mood or actually cracks a joke,she goes right back to being "dark and twisty."

In the 15th season, Meredith actually lost her job because of a huge mistake that she made: she was guilty of insurance fraud. This is surprising because back in season seven, Meredith was working on an Alzheimers' clinical trial and shecheated in order to get the results that she wanted.

RELATED:Grey's Anatomy: 10 People Meredith Should Have Been With (Other Than Derek)

It's pretty crazy that Meredith doesn't learn from her professional mistakes and that she seems to be doing the same thing over and over again.

Many fans have said that the interns arelackluster onGrey's Anatomyand while that's true, it's hard not to feel bad for them. The other characters do treat them pretty badly and act like they have no reason for being at the hospital.

Meredith is definitely the worst when it comes to this... but she acts this way toward the doctors on her own level, too. Meredith got worse and worse on the show because shealways wants things done her way, and she doesn't want to listen to someone else's opinion.

Derek's death was a major moment onGrey's Anatomyand yet it was treated so weirdly. Meredith literally runs away and doesn't mourn his death with the other characters, which is what long-time fans would have expected.

It seems like a poor creative choice to have Meredith disappear. This took her out of the main story and didn't make any sense. It's yet another example of how this character has gotten worse over the many seasons that the show has been onthe air.

Meredith is the kind of doctor who believes that she's so talented that she can't ever be wrong. Whenever she messes up at the hospital or in her personal life and someone tells her that she did something wrong, she can't admit it.

RELATED:Grey's Anatomy: 10 Things You Never Noticed About The First Episode

Meredith's stubborn attitude is another way that she got worse as the show went on. It's a major character flaw that never gets any better.

It's true that Meredith hasn't had an easy road and that her life could definitely be a lot better. But her constant self-defeatist attitude is tough to watch as it's so repetitive.

Meredith really believes that bad things are always going to happen to her and it sometimes seems like that's a self-fulfilling prophecy. It can get really old having to watch her approach life in such a negative way all the time.

After Derek's death, Meredith keeps trying to date someone new and then something inevitability goes wrong. It feels like watching the same storyline over and over again and it's frustrating.

From Nathan Riggs (Martin Henderson) to Andrew DeLuca (Giacomo Gianniotti), Meredith thinks that she can open herself up to love again and then decides that she can't. She seems to take the easy way out and finds a lot of excuses for why she has to be single.

Another problem with Meredith's character? She always acts like other people are out to get her, and she never trusts new people or even her own family.

Whether it's Amelia (Caterina Scorsone) or Maggie (Kelly McCreary), Meredith doesn't welcome her sisters with open arms and, in fact, keeps them at arm's length for quite a while. It feels like she never grows as a person, that's for sure.

NEXT:Grey's Anatomy: 5 Things It Got Right About A Doctor's Life (& 5 Things It Got Wrong)

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Aya Tsintziras writes about travel and pop culture. She loves coffee, barre classes, avocado, and watching TV. She lives in Toronto with her husband.

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Greys Anatomy: 10 Ways Meredith Got Worse And Worse - Screen Rant

Grey’s Anatomy: What happened to Derek Shepherd? Why did Patrick Dempsey leave? – Express.co.uk

WARNING: This article contains spoilers from Grey's Anatomy.

Dr Derek Shepherd (Patrick Dempsey) was an iconic character in Grey's Anatomy and was often referred to as "McDreamy".

He had an on and off relationship with Dr Meredith Grey (Ellen Pompeo) until they settled down in season five.

The pair then legally got married in series eight so they could adopt their daughter Zola.

For the next few seasons, it seemed they had the perfect little family but this was destroyed in 2015.

READ MORE:Grey's Anatomy: What happened to April Kepner?

In season 11, episode 21, called How to Save A Life, Derek was on his way to Washington to quit a brain-mapping project.

While making his way there, he sees a car accident and stops to help.

He manages to save not only a young girl and her mother but another couple who was involved in the crash.

Believing his duty had been done, Derek got back in the car to continue his journey.

But just moments later, Derek's car was hit by a truck and he was subsequently rushed to hospital.

Talking to People magazine in 2015, actor Dempsey opened up about leaving the show as he wanted to have more "control" of his time.

Dempsey said: "Im very grateful for Greys Anatomy.

"Its given me the opportunity to do everything. But at the same time, there was a cost.

"I think after a certain period of time, no matter how much money you make, you want control out of your own schedule."

He then explained a year later to the same publication: "It had been long enough. It was time for me to move on with other things and other interests.

"I probably should have moved on a couple of years earlier."

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Grey's Anatomy: What happened to Derek Shepherd? Why did Patrick Dempsey leave? - Express.co.uk