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Ireland could return to normal in weeks if there were no new COVID-19 infections – Dublin Live

Ireland could return to normal in less than a month if there were no new coronavirus infections, an expert has said.

Prof Luke O Neill, Professor of Biochemistry at Trinity College Dublin, stressed the importance of social distancing and self isolation as we work to battle the highly contagious virus.

He was speaking to Pat Kenny on Newstalk this morning, and said that if people don't isolate, the pandemic could continue for "months and months" as COVID-19 spreads from person to person.

A listener submitted a question asking that if, in theory, there were no new cases confirmed in Ireland from today, when the pandemic would end.

He said: "If everything stopped now - the virus spends two, three weeks in your body.

"You can imagine, that if there's no more infections, after two or three weeks or so that the virus goes away.

"It's as simple as that, you see."

He continued: "The longer people meet and infect each other it starts again in the next person.

"Let's say you're on day 13 of a 14 day cycle and you infect someone else - they're going to go for 14 days now.

"And then if they infect someone on day 12, another 14 days. It can go on for months and months."

During the chat, he revealed that there are currently 35 separate vaccines under development across the world.

He also clarified what surfaces are most likely to still have coronavirus on them if touched by someone infected.

He said: "They're (scientists) plugging away, they just can't predict it. But they're certainly pressing away like crazy - it will come.

"Each trial might be slightly different - there's subtle differences between them all.

"The surfaces it (coronavirus) likes most are glass and metal. It can still live on paper for a few hours."

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Ireland could return to normal in weeks if there were no new COVID-19 infections - Dublin Live

Scientists detected trace amounts of superconducting material in Meteorite – Tech Explorist

Meteorites can contain a wide range of material phases due to the extreme environments found in space. They are ideal candidates to search for natural superconductivity.

Although, due to their chemically inhomogeneous nature and minute superconducting phases, rendering detection becomes difficult.

In a recent study, scientists from the UC San Diego and Brookhaven Laboratory in New York used ultrasensitive magnetic field modulated microwave spectroscopy (MFMMS) technique and studied meteorite samples.

They identified the presence of superconducting material in two meteorites: Mundrabilla and GRA 95205.

Mundrabilla is an iron-sulfide-rich meteorite from a class formed after melting in asteroidal cores and cooling very slowly. GRA 95205, on the other hand, is a ureilite meteoritea rare stony-like piece with unique mineral makeupthat underwent heavy shocks during its formation.

Scientists characterized the meteorites phases as alloys of lead, tin, and indium (the softest non-alkali metal).

Mark Thiemens, a distinguished professor of chemistry and biochemistry at UC San Diego, said, meteorites with extreme formation conditions are ideal for observing exotic chemical species, such as superconductorsmaterials that conduct electricity or transport electrons without resistance. However, the uniqueness of superconductive materials occurring in these extraterrestrial [minor] planets.

Ivan Schuller, a distinguished professor in the Department of Physics with expertise in superconductivity and neuromorphic computing at UC San Diego, said,Superconductivity in natural samples is extremely unusual. Naturally collected materials are not phase-pure materials. Even the simplest superconducting mineral, lead, is only rarely found in its native form.

This study was supported by the Air Force Office of Scientific Research (grant FA9550-14-1-0202); and the UC San Diego Chancellors Associates. The U.S. Department of Energy supported transmission electron microscopy work at BNL, Office of Basic Energy Science, Division of Materials Science and Engineering (contract no. DE-SC0012704).

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Scientists detected trace amounts of superconducting material in Meteorite - Tech Explorist

Trinity Professor outlines steps that would see pandemic ended in 2-3 weeks – Extra.ie

Life could get back to normal in Ireland in just three weeks if everyone was to self-isolate and stay indoors, an expert has said.

Posts on social media over the weekend indicated that many were not taking social distancing seriously as clusters gathered around in towns.

Luke ONeill, Professor of Biochemistry in the School of Biochemistry and Immunology at Trinity College Dublin has warned that the longer people meet and infect each other, the longer this crisis goes on.

Gardai have also warned parents that the ongoing health issue in Ireland is extremely serious and children and teens should be abiding by social distancing.

Speaking to Pat Kenny on Newstalk, a listener asked the professor if, hypothetically, there were no new cases of COVID-19 tomorrow, how soon could things get back to semi-normal.

The virus lasts around two to three weeks in our bodies, Professor ONeill explained.

If you can imagine if there are no more infections and if everything stopped now, after 2-3 weeks the virus will go away.

Its a matter of weeks.

Taoiseach Leo Varadkar has previously warned that the outbreak could last until the summer.

The longer people meet up and infect each other, the longer this will all last.

The professor explained that if one was on day 13 of a 14-day infection cycle and goes out and infects someone else, the virus will then live on for another 14 days.

He also referred to Germany who has now shut all restaurants, barbershops and tattoo parlours as well as banning the gathering of groups of more than two people.

We should do exactly what theyre doing now, he said.

Another listener asked if children can see their grandparents after theyve been off school for two weeks and have shown zero symptoms however ONeil insisted that we keep social distancing.

The NPHET has also warned that public spaces such as parks and beaches could also close.

In positive news, ONeill mentioned that 30 separate trials for a COVID-19 vaccine will run out in April that hopefully is the beginning of something new.

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Trinity Professor outlines steps that would see pandemic ended in 2-3 weeks - Extra.ie

Companion Animal Diagnostic Market Size to Reach $3.1 Billion by 2026 – Reported Times

Global Companion Animal Diagnostic Market By Technology (Clinical Biochemistry, Molecular Diagnostics, Immunodiagnostics, Urinalysis, Hematology, and Other), By Animal Type (Dogs, Cats, Horses, and Others), By End-User (Diagnostic Laboratories, Veterinary Hospitals & Clinics, Research Institutes & Universities), By Application (Bacteriology, Parasitology, Virology, Clinical Pathology, Others); By Region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa); Trend Analysis, Competitive Market Share & Forecast, 2016-2026

The Global Companion Animal Diagnostic Market is estimated to grow at a CAGR of 9.08% during the forecast period 2019-2026. As per the analysis, the global Companion Animal Diagnostic market was valued $1.69 billion in the year 2019 and estimated to reach $3.1 billion by the end of the year 2026. The global market growth is driven by increased adoption of companion animals globally, growth in number of chronic diseases among animals and increasing demand of efficient diagnostics for pet animals.

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Diagnostics tests help in early detection, prevention and control of animal diseases. Increasing demand for fully automated and semi-automated diagnostic tests techniques further support the demand of companion animal diagnostics, which result in increased productivity and help to handle the large volumes of samples. Increasing demand of Point of Care Diagnostics (POCD) will additionally boost the growth of the companion animal diagnostics market. In the market study, it was analyzed that market players are hugely investing in research and development of POCD equipment.

Market Insights

Increasing adoption of pet animals majorly driving the market growth

Growing adoption of companion animals, especially in developed countries, to cope up with emotional disorders and loneliness, or for support, amusement for kids, and sometimes security, are some of the key factors driving the market growth. Moreover, increasing focus of pet-owners towards preventive healthcare, regular health checkup, and increasing expenditure on companion animal healthcare to protect them from different infectious and other diseases such as zoonotic diseases is propelling the market growth. Moreover, the increasing demand for rapid tests and portable instruments for point-of-care services and the use of sophisticated technologies like machine learning is presumed to offer potential growth opportunities for market players in the forthcoming years.

Increasing pet care cost restraint the market growth

The pet care cost is increasing due to the increasing adoption of companion animals. The initial cost of adoption and the whole expenses of the pet owner during the year is high, which is restricting the growth of the market.

Segmentation Overview of the Global Companion Animal Diagnostic Market

The Global Companion Animal Diagnostic Market is segmented on the basis of Technology, Animal Type, End-User and Application. These market segments are further categorized into sub-segments to study the market in detail.

On the basis of Technology Segment, the Global Companion Animal Diagnostic Market is Sub-Segmented into:

On the basis of Animal Type Segment, the Global Companion Animal Diagnostic Market is Sub-Segmented into:

On the basis of End-User Segment, the Global Companion Animal Diagnostic Market is Sub-Segmented into:

On the basis of Application Segment, the Global Companion Animal Diagnostic Market is Sub-Segmented into:

Global Companion Animal Diagnostic Market: Regional Insights

Geographically, the global Companion Animal Diagnostic market is segregated into North America, Europe, Asia Pacific, Latin America and Middle East & Africa. North America is estimated to register the largest revenue share in the target market, owing to higher adoption of companion animals in nations such as the US and Canada in the region, high pervasiveness of chronic diseases, increasing initiative by the government, well-established veterinary healthcare infrastructure. Additionally, North America has strong existence of prominent companies involved in companion R&D of innovative therapeutics and animal diagnostics. Higher spending on pet healthcare is a major factor growth driving factor.

Competitive Landscape

The companies that hold the major share of global Companion Animal Diagnostic market are Scil Animal Care Company GmbH Bionote Inc., Skyla Mindray Medical International Limited, Randox Laboratories, Ltd., IDvet, Fujifilm Holdings Corporation, INDICAL Bioscience GmbH Corporation, Biomrieux SA, Neogen, Virbac, Thermo Fisher Scientific Inc., Heska Corporation IDEXX Laboratories, Inc., Zoetis Inc., Abnova Corporation, Guardant Health, Inc., Illumina Inc. QIAGEN N.V., and other prominent players.

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Companion Animal Diagnostic Market Size to Reach $3.1 Billion by 2026 - Reported Times

Want To Get Away? These Astronauts Talk About Life Off Earth, Dealing With Isolation and Facing Fears – WMFE

Scott Kelly on the International Space Station. Photo: NASA

Since our podcast and radio show Are We There Yet? is celebrating its 4th birthday and many of us are quarantined at home with lots of free time our host Brendan Byrne is sharing his favorite conversations with astronauts.

Listen back to his picks on this binge-able list and be sure to subscribe to the podcast, or listen in every Tuesday at 6:30 p.m. ET on WMFE and WMFV.

Scott Kelly spent almost a year in space as part of an experiment to understand how our bodies function for an extending time in microgravity. He spoke to Byrne about the physiological challenges of life off Earth and the emotion toll isolation took on his mind. Kelly recently wrote an op-ed in the New York Times about his time in isolation and his tips for folks during the coronavirus pandemic.

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Canadian astronaut Chris Hadfield most famously spent his time isolated on the International Space Station filming a music video set to David Bowies Space Oddity. But Hadfields trip wasnt all fun and games there was real danger. He spoke with Byrne about how he deals with fear and the unknown.

LISTEN: WMFE

Nicole Stott is a frequent flier on the podcast. On her first appearance on the show, she talks about the hobby she brought up with her for her long stay on the ISS a set of watercolor paints. She tells Byrne about how her time in space gave her a fresh perspective on life down on Earth.

LISTEN: WMFE | Apple Podcasts | Spotify

Space stinks. Well, it doesnt stink until you come back. NASA astronaut Bruce Melnick talks about the wall of smell that hits you when you return to Earth on the Space Shuttle. Melnick also tells Byrne about the challenges of using the space toilet. Really high-brow stuff, we promise.

LISTEN: WMFE | Apple Podcasts | Spotify

Before making history as part of the first all-female spacewalk, Jessica Meir joined the podcast to talk about her expertise the physiology of animals in extreme environments and how the lessons learned will help get humans back to the moon and on to Mars.

LISTEN: WMFE | Apple Podcasts | Spotify

Do you have a favorite episode? Share it with Brendan Byrne and the rest of the space fans out there shoot us an email at AreWeThereYet@wmfe.org

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Want To Get Away? These Astronauts Talk About Life Off Earth, Dealing With Isolation and Facing Fears - WMFE

Fertility wearable to double as COVID-19 temp monitor, as need for population data intensifies – BioWorld Online

Gleaning reliable population-level temperature data routinely has been a key component of the more successful efforts in several Asian countries for containing the emerging, novel coronavirus. But these often have required highly time and labor-intensive coordinated efforts to screen people manually as they access various services such as public transportation and grocery stores.

Remotely monitoring people for the early signs of COVID-19, as well as determining disease progression for infected patients virtually, would offer huge potential advances in better protecting the populace, as well as lessening the burden on swamped health care providers.

Into the gap

Zurich-based startup Ava Science Inc. hopes to step into that gap. The company recently issued a public call for partners and funding to further research the potential usefulness of its fertility wearable, known as Ava Bracelet, during the COVID-19 pandemic.

The effort is not unprecedented; the primary COVID-19 treatment center in Shanghai, the Shanghai Public Health Clinical Center, has been using continuous temperature monitoring in hospitalized patients using wearable technology from Campbell, Calif.-based startup Vivalnk Ltd., which also has a China office. This freed health care staff from routine temperature checks.

Given the current pandemic, we have looked as a company at how we could repurpose our device to help combat the spread of COVID-19, Ava Chief Medical Officer and head of clinical development Maureen Cronin told BioWorld. Cronin was previously the Head of Womens Medical Affairs at Bayer Schering Pharma.

The Ava Bracelet provides the highly accurate temperature readings necessary for this application, as well as other vital sign monitoring. It is already in widespread use throughout the U.S. and Europe and has aided more than 30,000 women in getting pregnant. Ava, which has a U.S. headquarters in San Francisco, is starting to coordinate with various governments, nonprofits, academics and companies to explore the application of its Ava Bracelet for systematic COVID-19 monitoring.

We believe our device, the Ava Bracelet, could be used to detect early symptoms known to be associated with COVID-19 and are seeking funding to test our hypothesis directly, said Cronin. We know that our medical-grade device, worn nightly while the user sleeps, can pick up subtle changes in breathing rate, heart rate, and temperature; the user syncs the device each morning with a smartphone app that shows them how their physiological parameters have changed over the last days, weeks and months.

The nightly log of changes in biophysical data could provide critical insights for first responders and/or people with known or suspected exposure quarantining at home, indicating when they may want to seek medical advice, she continued. Additionally, this data could be shared with health care professionals at time of triaging to demonstrate the trajectory and/or severity of the disease. We believe the Ava bracelet could even serve as a remote surveillance tool in hospital wards, reducing the need for health care professionals to take in-person vitals and thereby minimizing the risk of additional transmission.

In Europe, the device has a CE mark to measure the physiological parameters to facilitate conception and to provide general health and wellness information. In the U.S., where it launched in 2016, FDA approved it as a low-risk class I device for use in conception and physiological changes in subsequent pregnancies. Ava aims to submit to European regulators later this year for a contraception indication.

Remote monitoring priorities

The Ava Bracelet is a wrist worn device that is worn nightly to track breathing rate, pulse rate, skin temperature, heart rate variability, perfusion as well as sleep quality and quantity. Its initial fertility aim was to replace the common fertility practice of monitoring basal body temperature every morning prior to leaving bed to predict when ovulation is most likely to occur.

The most common COVID-19 symptoms are fever, dry cough and shortness of breath, according to the World Health Organization. These occur at a rate of 88%, 68% and 19%, respectively. Ava anticipates that it can detect a fever with both its body temperature and pulse rate monitors, which should both increase, while shortness of breath can be measured as an increased breathing rate. There is obviously no physiological reason why the wearable couldnt be used across genders.

The Ava Bracelet data is analyzed via machine learning to predict a five-day fertile window with 89% accuracy. Its been evaluated in several clinical trials and peer-reviewed manuscripts. The company said that it is currently evaluating data from its users for COVID-19 related trends, but declined to disclose anything further.

The FDA is prioritizing the expansion of the availability and capability of noninvasive remote monitoring devices to facilitate patient monitoring while reducing patient and health care provider contact and exposure to COVID-19 during this pandemic. It released guidance late last week that is designed to enable the smooth repurposing of existing devices and remove potential penalties for repurposing of these devices.

FDA does not intend to object to limited modifications to the indications, claims, functionality, or hardware or software of FDA-cleared non-invasive remote monitoring devices that are used to support patient monitoring during the declared public health emergency, the FDA stated in the new guidance.

Ava declined to name any specific potential partners in its COVID-19 efforts, but did say that it has the capacity to make 50,000 bracelets available shortly with the capacity to further ramp up production. The company has started offering a non-fertility version of the Ava Bracelet for $100 off the standard $249 price to individuals, researchers and medical professionals for physiology tracking.

We have had numerous requests for information and several requests for discussions, said Cronin. The requests have come from current users, potential users, governmental and non-governmental organizations, academics and industries. We are investigating several options as we speak.

We are working towards submitting a grant application for a public-private (academic and industry) grant proposal in Europe by the end of this week, she added. We are a very small organization, but we understand the need to act fast. We are investigating several other proposals in different regions throughout the world and remain open to other proposals.

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Fertility wearable to double as COVID-19 temp monitor, as need for population data intensifies - BioWorld Online

They Dont Hide From the Coronavirus, They Confront It – The New York Times

As the world writhes in the grip of Covid-19, the epidemic has revealed something majestic and inspiring: millions of health care workers running to where they are needed, on duty, sometimes risking their own lives. I have never before seen such an extensive, voluntary outpouring of medical help at such a global scale.

Intensive care doctors in Seattle connect with intensive care doctors in Wuhan to gather specific intelligence on what the Chinese have learned: details of diagnostic strategies, the physiology of the disease, approaches to managing lung failure, and more. The three-page, single spaced document, full of lessons, circulates immediately and widely through social media platforms, a gem borne of pure, professional commitment. Facebook starts a COVID-19 USA Physician/APP Group on March 13. It has 57,000 members on March 15, and 105,000 on March 18.

The Journal of the American Medical Association, even while moving its staff home for social distancing, sets new records for speeding helpful scientific studies, peer reviewed, onto the web. Knowledge grows. One JAMA paper is by a group of Wuhan physicians reviewing patterns and outcomes for 1099 patients, showing surprisingly high rates of severe illness in younger adults. Another is an honest account by physicians in Lombardy of both successes and mistakes as they grapple with unprecedented intensive care demands. A list-serve for hospitals started by the Institute for Healthcare Improvement overflows with questions What have you learned about setting up drive-by testing? Has anyone found a new source of masks? and instant answers from institutions and clinicians.

One anesthesiologist in Valhalla, N.Y., types in a suggestion: Instead of giving up when the ventilators are all in use, how about asking groups of students or family members who have become immune to the virus to ventilate patients manually, using Ambu bags, in shifts even for days at a time? Clinicians reply, some critical, some supportive, and all trying to find answers.

And city by city, hospitals mobilize creatively to get ready for the possible deluge: bring in retired staff members, train nurses and doctors in real time, share data on supplies around the region, set up special isolation units and scale up capacity by a factor of 100 or 1000. On Tuesday, Mayor Bill de Blasio of New York asks for retired medical personnel to join the citys Medical Reserve Corps; 24 hours later, 1000 new volunteers have signed up. Northwell Health, a 23-hospital system in New York City, figures out how to add 1,500 beds, if needed, by repurposing space.

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They Dont Hide From the Coronavirus, They Confront It - The New York Times

Avectas and Vycellix Announce Collaboration to Advance Next-Generation Solutions for the Optimized Manufacture of Cell & Gene Therapies – P&T…

DUBLIN and TAMPA, Florida, March 24, 2020 /PRNewswire/ -- Avectas, a cell engineering technology business and Vycellix, Inc. an immuno-discovery cell & gene therapy company, today announced that the companies have entered into a collaboration agreement to develop proprietary approaches for cell-based immunotherapeutic products.

The companies will collaborate on the delivery of Vycellix's novel RNA immunomodulator VY-M using Avectas' cell engineering platform, Solupore. The collaboration will address current limitations for cell-based therapies, in particular with respect to the need to accelerate the manufacturing process, reduce the cost of manufacture, and ultimately improve patient outcomes.

"We are delighted to partner with Vycellix and join forces in the development of novel cell-based products," says Michael Maguire, PhD, CEO of Avectas. "We believe Solupore will play a critical role in the manufacture of cell-based therapies and will support a path towards effective patient outcomes."

According to Vycellix's President, Douglas Calder, "Solupore represents a new paradigm for delivery of transgenes, and our initial studies will evaluate Solupore to deliver our new product candidate, VY-M, to T cells and NK cells. We expect to accelerate the expansion-time of T cells and NK cells by decreasing the non-dividing lag time, resulting in much shorter "vein-to-vein" delivery-time to patients." The studies will be conducted at Avectas' Dublin-based facility and at Karolinska Institutet, Stockholm, Sweden.

Both Avectas and Vycellix are collaborative partners within NextGenNK, a newly established competence center for development of next-generation NK cell-based cancer immunotherapies based at Karolinska Institutet, Stockholm, Sweden. It is envisioned that Avectas and Vycellix will further expand their collaboration within the NextGenNK constellation.

"We are excited to see the NextGenNK competence center catalysing interactions among its industrial partners to advance NK cell-based immunotherapies," says Hans-Gustaf Ljunggren, MD PhD, Director of the NextGenNK competence center. "The present collaboration may pave the way for similar collaborations among NextGenNK partners."

In February 2020, Avectas announced that it had entered an agreement with the Centre for Commercialization of Regenerative Medicine (CCRM) based in Toronto, Canada to accelerate the translation of Avectas' non-viral cell engineering platform (Solupore) into the clinic.

About Avectas:Avectas is a cell engineering technology business developing a unique delivery platform to enable the ex-vivo manufacture of our partners' gene-modified cell therapy products, which will retain high in-vivo functionality. Our vision is to be a leading non-viral cell engineering technology provider, integrated into manufacturing processes for multiple autologous and allogeneic therapies, commercialized through development and license agreements. For more information, please visit the Company's website at http://www.avectas.com

About Vycellix:Vycellix, Inc.is a private, immuno-discovery, life science company at the forefront of innovation in the development of cell & gene-based therapies targeting indications in, but not limited to, hematology/oncology, autoimmunity/chronic inflammatory diseases, and organ/tissue transplantation.

The Company's platforms were all initially discovered by scientists at the world-renowned Karolinska Institutet (KI) in Stockholm, Sweden. KI is globally recognized for its Nobel Assembly, which awards the Nobel Prize in Physiology or Medicine. For more information, please visit the Company's website at http://www.vycellix.com

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Avectas and Vycellix Announce Collaboration to Advance Next-Generation Solutions for the Optimized Manufacture of Cell & Gene Therapies - P&T...

Anatomy of a coronavirus disaster: how 2,700 people were let off the Ruby Princess cruise ship by mistake – The Guardian

On Thursday, the Ruby Princess cruise ship docked in Sydney harbour after an 11-day round trip to New Zealand.

Despite the ship previously logging 158 cases of illness on an earlier voyage, all 2,700 passengers on board were allowed to disembark at Sydneys Circular Quay and return to their homes in New South Wales and interstate.

So far, 133 people have been diagnosed with the disease after leaving the ship, and one person, a woman in her 70s, has died.

The NSW health minister, Brad Hazzard, admitted on Sunday that this was a mistake to let passengers disembark, and on Monday the prime minister, Scott Morrison, said the Australian defence force had been called in to help NSW Health track the passengers contacts.

How did a public health disaster like this happen?

The Ruby Princess arrived in Sydney on 8 March, having sailed from Port Chalmers in New Zealand on a previous tour.

According to the ships internal logs, 158 passengers on board were sick, with 13 registering high temperatures. Nine were tested upon arrival, according to the Australian newspaper. However, all passengers were allowed to disembark, including a Northern Territory couple who flew to Darwin, and later tested positive for Covid-19.

The ship was rated medium risk by NSW Health as a result of the 158 cases of illness.

Hours later, 2,700 new passengers boarded the ship in Sydney, and it set sail that night for another return trip to New Zealand.

According to ship tracker Marine Traffic, the Ruby Princess docked in Port Chalmers on Thursday 12 March, Wellington on Saturday 14 March and Napier on Sunday 15 March.

Five people developed influenza-like illness by Wellington on 14 March, NSW Health revealed a week later on Friday 20 March. They tested negative for Covid-19 at that time, NSW Health said.

On Sunday 15 March, the Ruby Princess left Napier and set a course for Sydney 63% of the passengers were Australian residents, 20% were American residents and the remaining 17% were from other countries.

Elisa Mccafferty, a passenger on the ship, told Guardian Australia that people were told to fill in a form declaring if they had a cough or fever, but at no point did the Ruby Princess inform passengers that there were suspected cases of coronavirus on board.

The Ruby Princess arrived in Sydney harbour. All of its 2,700 passengers were allowed to disembark at Circular Quay, with many heading immediately to domestic flights.

Despite being deemed medium risk a week earlier, the ship was deemed low risk that day because it had only travelled between New Zealand and Australia.

One passenger was unwell and taken directly from the ship to hospital, two presented to Sydney hospitals for testing after disembarking, and one was a crew member who was placed into isolation on the ship.

All four would later test positive for Covid-19, but the results of these tests would not be disclosed until Friday. The woman who was taken directly to hospital died on Tuesday morning.

Passenger Bill Beerens would later tell the ABC that he had a cough when he left the ship on Thursday, but was allowed to go home without testing. He went to a hospital that night and his test came back positive on Saturday.

He said other passengers near him also had coughs and sore throats.

Mccafferty said: At no point was anybody checked. As we were disembarking, they basically just scanned us off in groups. And we were let go. We didnt see any temperature scanning, nobody was pulled aside that we could see.

All passengers were told they would need to self-isolate at home or in a hotel for 14 days.

NSW Health announced that four passengers from the ship had tested positive, but all had disembarked and had already started journeying home, including interstate.

The health department said they began calling passengers, emailing and texting to inform them of the confirmed cases, and remind them to self-isolate and monitor for symptoms.

A spokesman for Princess Cruises told Guardian Australia that our onboard medical team was rigorous in its treatment of some guests who reported flu-like symptoms, and these guests were isolated.

The ship reported these cases to NSW Health, which in turn requested swabs to be provided following the ships arrival in Sydney, some of which subsequently tested positive for Covid-19.

NSW Health did not respond in time for publication about what assessments they conducted on passengers, and whether they knew if any passengers had symptoms of Covid-19.

On Tuesday 24, the department said in a public statement that no cases of Covid-19 had been identified by doctors on board before docking.

Hazzard admitted that it was a mistake to allow the 2,700 passengers to disembark on Thursday without testing.

If I had my opportunity to have my two bobs worth, with the benefit of what we now know about those people, Id have said yeah, maybe we should hold them on the ship, he told reporters.

The number of confirmed cases from the Ruby Princess rose to 26 in total 18 in NSW and eight interstate.

The number of confirmed cases from the ship rose to 48 in total 27 in NSW, and 21 interstate.

Morrison told parliament that NSW Health was responsible for allowing the passengers to disembark, and that the Australian Defence Force had been called in to help the department trace the contacts of the infected passengers.

The vessel was placed under the control of the NSW authorities including NSW Health and the NSW port authority, he told parliament. NSW Health has stated it undertook a full assessment of the Ruby Princess and allowed passengers to disembark.

Yesterday the ADF provided assistance to the NSW health department to provide contract tracing support [and] contact tracing activities relating to passengers from this vessel.

In a statement, the defence minister, Linda Reynolds, said ADF contact tracing support teams were being established in all states and territories.

The number of confirmed cases from the ship rose to 133 in total 107 in NSW, and 26 interstate.

A woman in her 70s, who was among the first four who tested positive, died in a Sydney hospital.

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Anatomy of a coronavirus disaster: how 2,700 people were let off the Ruby Princess cruise ship by mistake - The Guardian

15 Polarizing TV Character Exits From Grey’s Anatomy, Buffy and More – Yahoo Entertainment

Saying goodbye to a beloved TV character is always tough, but it becomes even harder when something about their departure feels off.

As the debate surrounding Alexs exit from Greys Anatomy rages on 48 percent of TVLine readers still hate that Karev randomly reunited with secret-mom Izzie, while 25 percent love it and 27 percent admit to being somewhere in the middle we thought wed look back at some other polarizing TV departures on which we also admit to being somewhere in the middle.

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Quick disclaimer: This is more about the manner in which a key characters story was wrapped up, not the mere fact that an actor left a long-running show. For example, Nina Dobrevs departure from The Vampire Diaries after six seasons certainly sent shockwaves through the CW dramas fandom, but her characters exit storyline Elena was placed under a sleeping curse, keeping her somewhat in the picture was largely well-received by fans. In other words, not polarizing.

No, were talking about those truly WTF character departures that either had you screaming at your TV in disgust or desperately Googling in confusion. From unnecessary deaths on shows like Veronica Mars and Buffy the Vampire Slayer to unceremonious exits on shows like Lizzie McGuireand Law & Order: SVU, weve assembled 15 of TVs messiest conclusions.

And heres another disclaimer: Because were discussing major exits from more than a dozen TV shows, it should go without saying that this gallery is a spoiler minefield. Youve been warned.

Browse our gallery of some of TVs most polarizing exits you can click here for direct access thendrop a comment with your thoughts below. Which befuddling character departures would you add to our list?

Launch Gallery: TV's Most Polarizing Exits

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15 Polarizing TV Character Exits From Grey's Anatomy, Buffy and More - Yahoo Entertainment