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Neuroscience

How Early Visual Experience Creates The Binocular World – Technology Networks

NewsMay 19, 2020| Original story from the Max Planck Florida Institute for Neuroscience

Featured illustration: In the mature visual cortex, similar modular patterns of activity are observed when the same orientation is shown to the left or right eye. In contrast, early in development, markedly different patterns of activity are observed for the same stimulus, resulting in a monocular mismatch that reflects misalignment of the orientation representations from the two eyes. Credit: MPFI

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How Early Visual Experience Creates The Binocular World - Technology Networks

Neuroscience

Study shows impact of childhood adversity on neuropsychological functioning in adulthood – News-Medical.Net

Reviewed by Emily Henderson, B.Sc.May 22 2020

A team of researchers from the University of Southampton, the University of Bath and King's College London, have provided compelling evidence of the impact of adversity in childhood on neuropsychological functioning in adulthood. They also showed that neuropsychological difficulties may explain why early adversity is linked to attention deficit hyperactivity disorder (ADHD) in later life.

Their study, published in the journal Psychological Medicine, analysed neuropsychological function in 70 young adults who were exposed to severely depriving conditions in Romanian orphanages during Nicolae Ceausescu's regime and subsequently adopted by British families. The adoptees were compared to 22 British adoptees of similar ages who had not suffered childhood deprivation.

As part of the research, the adoptees were asked to carry out tests to assess their neuropsychological functioning in five areas: controlling their responses (inhibitory control), prospective memory, decision-making, emotional recognition and cognitive ability (IQ). Prospective memory is the ability to remember to do something in the future, such as remembering to go to an appointment or what you need to buy if you don't have a shopping list. ADHD and autism spectrum disorder (ASD) symptoms were assessed through questionnaires completed by their parents.

The results showed that the Romanian adoptees had lower IQs and performed less well on the other four tests when compared to the adoptees who had not suffered deprivation. The adoptees with the lowest IQs and the greatest problems in prospective memory were more likely to show ADHD symptoms in adulthood than those without neuropsychological difficulties. The researchers found no direct link between ASD symptoms and neuropsychological performance.

The latest research is part of the wider English and Romanian Adoptees study, a collaborative study between the University of Southampton and King's College London which began shortly after the fall of the communist regime in Romania.

Children living in the institutions were subjected to extremely poor hygiene, insufficient food, little affection and no social or cognitive stimulation. The study analyses the mental health and brain development of 165 children who spent time in Romanian institutions and who were adopted by families in the UK when aged between two weeks and 43 months.

The principal investigator of the study is Professor Edmund Sonuga-Barke, who began the study whilst working at the University of Southampton and is now based at the Institute of Psychiatry, Psychology & Neuroscience at King's College London.

Speaking of the latest research, Professor Sonuga-Barke said: "This study contributes to our changing understanding of the power of the early environment to shape brain development -showing that the effects of institutional deprivation on cognition can still be seen after more than twenty years of positive experience in high functioning and loving adoptive families leads us to acknowledge that there are limits to the brain's recuperative powers."

The study highlights that institutional deprivation can have long-lasting effects on a range of neuropsychological functions that are important in everyday life, such as memory and general intellectual ability. Our findings also emphasize the importance of improving the quality of care for children in institutions."

Dr. Dennis Golm, Lecturer in Psychology, University of Southampton

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Study shows impact of childhood adversity on neuropsychological functioning in adulthood - News-Medical.Net

Neuroscience

The Psychedelic Science of Pain – Newswise

Newswise In the last few years, new research has demonstrated the powerful potential for classical psychedelics, especially psilocybin (the active compound in magic mushrooms), to treat a range of mental health disorders, including depression, anxiety and addiction. In 2018, the FDA assigned psilocybin a Breakthrough Therapy Designation. In response, UC San DiegosArthur C. Clarke Center for Human Imaginationorganized a new collaboration with groups across campus, including the Center for Human Frontiers at the Qualcomm Institute and the Departments of Anesthesiology and Psychiatry, to launch the Psychedelics and Health Research Initiative (PHRI). Its mission is to study the potential of psilocybin and other related compounds to promote healing and help manage pain.

While much of the new research on psychedelics shows its potentially high efficacy for treating psychological disorders, relatively little research has been done to demonstrate their uses for the treatment of chronic pain conditions.

A recentlypublished review paperby UC San Diego PHRI members Timothy Furnish, associate clinical professor of anesthesiology and pain medicine; Joel Castellanos, pain physician for UC San Diego Health and Adam Halberstadt, associate professor of psychiatry,among others, points to the potential for psychedelics to address chronic pain conditions.

Since pain has both physical and affective/cognitive components, the PHRIs preliminary findings indicate that psychedelics, alone or as part of multi-pronged treatment, can produce significant, meaningful and lasting reductions of chronic pain conditions such as cluster headache, complex regional pain disorder, phantom-limb pain, tinnitus and others. As a non-addictive alternative to opioids, psychedelics represent a revolutionary and much-needed new approach to the treatment of pain.

Neuropathic pain conditions such as phantom limb pain are often difficult to treat, says Furnish. The possibility that psychedelics could reorganize pain pathways in the brain holds out the promise of a much more long-lasting treatment than current medication can offer.

History of psychedelics research on campus

Research on the classical psychedelics, which include LSD, DMT, mescaline and psilocybin, has a long history at UC San Diego. Mark Geyer, Distinguished Professor of Psychiatry and Neurosciences Emeritus and founding member of the PHRI, has conducted research on the behavioral and neurobiological effects of psychedelics for more than 40 years at UC San Diego. He also helped start the Heffter Research Institute in 1993, dedicated to renewing research into beneficial uses of psychedelicsresearch that had been cut off prematurely during the 1970s.

The research pioneered by the Heffter group has already provided breakthroughs in our understanding of the neurobiology and therapeutic potential of psychedelics, says Geyer. It is clear that further such research will result in currently unimagined treatments for human illness and a deeper understanding of human nature.

Though the roots of this research go back decades at UC San Diego, the seeds of the PHRI began with a 2016 accident in the desert involving UC San Diego researcherAlbert Yu-Min Lin. A Qualcomm Institute research scientist and National Geographic Explorer, Lin lost his lower leg in that accident. Afterwards, he experienced debilitating phantom-limb pain, the sensation of pain seeming to come from the missing limb.

After losing my leg, says Lin, I faced two immediate challenges. The first was rebuilding mobility, which could be done with prosthetics. The second was remapping my mind to let go of extreme pain that seemed to come from a body part that was no longer physically there. Luckily for me, the authority on the topic of phantom pain happened to be a UC San Diego faculty member, V.S. Ramachandran.

Pioneering method, neuroplasticity

While Mirror Visual Feedbackthe method pioneered by Ramachandran, distinguished professor of psychology and neurosciences, for treating phantom-limb painprovided temporary relief, Lin observed that when the mirror was removed the pain came rushing back, as if my mind just wouldn't let it go.

But psilocybin provided the profound relief he sought. A 2018 case study published inNeurocase, co-authored by Ramachandran, Chaipat Chunharas, Zeve Marcus and Furnish, documents Lins experience: a single session with psilocybin resulted in immediate, persistent and profound reduction in what had been debilitating post-trauma pain caused by an amputation.

Freeing myself of the pain gave me back my life, says Lin, who is the director of theCenter for Human Frontiersbased at the Qualcomm Institute.

But the use of psilocybin to treat phantom limb pain has not been researched in a controlled, rigorous way. Some studies in Japan in the 1970s used LSD with phantom-limb sufferers, with small but suggestive results.

Recent studies have shown that exposure to psychedelic drugs promotes neuroplasticity. Based on those existing findings, psilocybin may be effective against phantom limb pain because it causes new functional brain connections and pathways to form in brain regions supporting body self-image and the experience of pain. On the other hand, it could be that the profound psychedelic experience facilitates a restart mechanism if you will, that modulates the feeling of pain, says Fadel Zeidan, PHRI member, associate director for research at the UC San DiegoCenter for Mindfulnessand assistant professor of anesthesiology.

Mindfulness of pain management

There is intriguing overlap with the research of Zeidan, who works to understand the effects of mindfulness meditation as a treatment for pain. His studies show that mindfulness reduces pain through multiple, unique brain processes that are distinct from placebo and other pain-relieving techniques. Recent research demonstrates that psychedelics produce states of mind and brain connectivity that are similar to those of experienced meditators, and that the twopsychedelics and mindfulnessare mutually supportive. Zeidan says that mindfulness meditation practice also promotes a restart button but one that you canpressin a moment-to-moment fashion.

Non-opioid treatments for pain conditionsincluding cluster headache, complex regional pain syndrome, phantom-limb pain, tinnitus and other forms of chronic paincould mean radical improvements for the more than 100 million sufferers in the United States alone, as estimated by the Centers for Disease Control and Prevention.

Future studies

According to the research team, these studies will provide a better understanding of how psychedelics can be used to treat pain, the mechanisms of action by which they produce their effects and how these phenomena illuminate new aspects of the healthy functioning of the brain. Such advances will help guide how the healthcare system can adapt to best deliver these radically different modes of intervention, all in the context of UC San Diegos world-class health and neuroscience research communities.

Pain is a very tricky thing, Lin says. It can be entirely consuming to those who bear it. But my experience with pain opened a window into the power within the mind to do extraordinary thingsto shift the perspective of pain, to potentially remap it awayand if that can help others it was all worth it.

PHRIfosters further novel basic and clinical research on the use of psychedelics for the treatment of pain and potentially other syndromes. The interdisciplinary team is currently planning the first pilot study of the potential effect of psilocybin on phantom-limb pain, to be followed by future clinical trials and brain imaging research.

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The Psychedelic Science of Pain - Newswise

Neuroscience

AI used to identify different types of brain injury – Business Weekly

Cambridge University researchers and colleagues from Imperial College London are putting the AI into brAIn. They have developed an AI algorithm that can detect and identify different types of brain injuries.

The researchers have clinically validated and tested the AI on large sets of CT scans and found that it was successfully able to detect, segment, quantify and differentiate different types of brain lesions.

Their results, reported in The Lancet Digital Health, could be useful in large-scale research studies, for developing more personalised treatments for head injuries and, with further validation, could be useful in certain clinical scenarios such as those where radiological expertise is at a premium.

Head injury is a huge public health burden around the world and affects up to 60 million people each year. It is the leading cause of mortality in young adults.

When a patient has had a head injury they are usually sent for a CT scan to check for blood in or around the brain and to help determine whether surgery is required.

Co-senior author Professor David Menon, from Cambridges Department of Medicine, said: CT is an incredibly important diagnostic tool but its rarely used quantitatively. Often, much of the rich information available in a CT scan is missed and as researchers we know that the type, volume and location of a lesion on the brain are important to patient outcomes.

Different types of blood in or around the brain can lead to different patient outcome, and radiologists will often make estimates in order to determine the best course of treatment.

Detailed assessment of a CT scan with annotations can take hours, especially in patients with more severe injuries, said co-first author Dr Virginia Newcombe, also from Cambridges Department of Medicine.

We wanted to design and develop a tool that could automatically identify and quantify the different types of brain lesions so that we could use it in research and explore its possible use in a hospital setting.

The researchers developed a machine learning tool based on an artificial neural network. They trained the tool on more than 600 different CT scans, showing brain lesions of different sizes and types. They then validated the tool on an existing large dataset of CT scans.

The AI was able to classify individual parts of each image and tell whether it was normal or not. This could be useful for future studies in how head injuries progress since the AI may be more consistent than a human at detecting subtle changes over time.

This tool will allow us to answer research questions we couldnt answer before, said Dr Newcombe. We want to use it on large datasets to understand how much imaging can tell us about the prognosis of patients.

Professor Menon added: We hope it will help us identify which lesions get larger and progress and understand why they progress so that we can develop more personalised treatment for patients in future.

While the researchers are currently planning to use the AI for research only, they say that with proper validation it could also be used in certain clinical scenarios, such as in resource-limited areas where there are few radiologists.

They also believe it could have a potential use in emergency rooms, helping to get patients home sooner. Of all the patients who have a head injury, only between 10 and 15 per cent have a lesion that can be seen on a CT scan.

The AI could help identify these patients who need further treatment, so those without a brain lesion can be sent home, although any clinical use of the tool would need to be thoroughly validated.

The ability to analyse large datasets automatically will also enable the researchers to solve important clinical research questions that have previously been difficult to answer, including the determination of relevant features for prognosis which in turn may help target therapies.

The research was supported in part by the European Union, the European Research Council, the Engineering and Physical Sciences Research Council, Academy of Medical Sciences/The Health Foundation and the National Institute for Health Research.

PHOTOGRAPH: Professor David Menon. Picture courtesy Cambridge Neuroscience

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AI used to identify different types of brain injury - Business Weekly

Neuroscience

‘We Won’t Quit’: Cheers To The High School Class of 2020 – KERA News

Your senior year is one for the ages.

Class trips, prom and graduation all help mark the end of one chapter and the start of another.

The pandemic has stolen some of these moments from the Class of 2020, but that hasnt kept seniors from celebrating a milestone year.

Listen to the KERA News story

The Bomb Factory was awash in strobe lights and fog on a recent Saturday night.

Hype men on stage were gassing up dueling DJs, spinning records that would usually make the dance floor irresistiblebut tonight, it was empty.

The Deep Ellum music venue mounted a virtual prom in lieu of the real thing.

Lewisville High School senior Kathryn Foster was watching from home.

I video called all my friends, and we got dressed up in the outfits wed already bought," Foster said. "I was in this big, blue dress that Id bought before we found out we werent going to come back to school.

She had fun, but it wasn't how Foster thought she'd be spending the months before she heads off to Baylor in the fall to study neuroscience.

It was kind of devastating for a lot of us to know that wed never get senior prom," she said. "We couldnt say goodbye to some of our friends who were going away."

It was dawning on seniors everywhere. Their last year was going to be very different from what they were expecting.

Demarre Johnson was enjoying spring break when he learned schools were closing indefinitely.

And we didnt know when we were going back or if we were going back," Johnson said. "Especially as a student athlete in his last year? That one hurt.

The class president at TownviewCenter in Dallas was slated to give a speech at his graduation ceremony.

"My mom was already planning on getting my whole family t-shirts with my face on it and a graduation cap," he said.

Johnson has a full ride to Babson College in Massachusetts, and his family has planned a drive-through graduation party.

You drive your cars through, you decorate your cars, you honk your horn, you scream and shout," he said. "As they leave, theyre going to throw their gifts in my trunk.

Jonah Ortiz isnt letting the shutdown keep him from celebrating either.

I just wear my button-up shirt, some slacks," Ortiz said. "My girlfriend already had her dress. I told her come over, and we can take some pictures. We took some pictures in my front yard, and that was kind of our little prom.

The senior at Sunset High School in Dallas is still figuring out whats next for him.

He might go to Cedar Valley College to become a mechanic, but he also has athletic scholarships to schools in Pennsylvania and Iowa.

"I'm scared," he said. "I'm definitely scared. I don't know what the future holds. I'm going to try my best to become a functioning member of society."

Emilie Garcia feels the same way.

I am terrified," she said. "I dont know what will happen in the fall. If my school does decide to open up, if my parents are going to take a risk by taking me, especially since they are older.

The valedictorian at Carter Riverside High School in Fort Worth plans to study engineering at Emory University.

These final senior year moments hold a special place in her heart.

I lost my brother my freshman year," Garcia said. "He was a senior, and he wasnt able to attend his graduation or his prom. For me, it was like closure. Knowing that I started high school with him, and I wasnt going to end it with him, but at least I was going to experience the events he didnt get to experience.

Garcia said she plans to wear her prom dress on the day of her virtual graduation. Her family will make her favorite dish, mole.

Shell also give a commencement speech.

I touch on the serial position effect, where you remember the first and last thing of a series best and the middle worst," she said. "Even though we will remember senior year forever, I know that the middle part truly enhanced our experience and made us who we are.

Garcia said she won't let the last few months define her journey so far.

Despite the fear and uncertainty they may feel about the future, this is a tough group of seniors.

Weve been through a lot," Johnson said. "We were born right at 9-11. We had to deal with that turmoil. Now, were going through one of the first ever lockdowns in history. I say one thing that the world will know about us is that we wont quit, and this is not the last youve heard of us.

So, lets raise a toast to the Class of 2020. The future is in good hands.

Got a tip? Email Miguel Perez atmperez@kera.org. You can follow him on Twitter @quillindie.

KERA News is made possible through the generosity of our members. If you find this reporting valuable, consider making a tax-deductible gift today. Thank you.

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'We Won't Quit': Cheers To The High School Class of 2020 - KERA News

Biochemistry

What scientists are learning to try to be ready for what’s after COVID-19 – Minneapolis Star Tribune

CHICAGO More than a decade ago, a center was founded at Northwestern University as a rapid-response operation against infectious disease. But its work was sporadic a boom when epidemics hit, a bust when they were under control.

Now, researchers with the Center for Structural Genomics of Infectious Diseases are rushing to find a treatment for COVID-19, making up for lost time. And they hope theyll be ready for whatever comes next.

I think were making substantial strides, said Karla Satchell, director of the center who is a professor of microbiology-immunology at Northwesterns Feinberg School of Medicine. Our hope is that we can do something in time to help this round of the pandemic. But at the very least, we can do enough that this wont happen again.

Andy Mesecar, an expert in biochemistry and gene therapy, is on the front lines of that fight. He has been working seven-day weeks, racing to find a drug for COVID-19, teaching at Purdue University and submitting daily reports to the National Institutes of Health.

His lab is one of the leading centers studying coronaviruses, and he and his team have dedicated nearly two decades to the research. With a background in biochemistry and structural biology, Mesecar started out studying enzymes that could fight cancer. He got into infectious diseases after the anthrax attacks in the weeks after 9/11. Then, he pivoted to studying enzymes that could be used against SARS when it surfaced in November 2002. My training in structural biology allows me to work on any diseases that go around, he said. I can apply it to any disease and do so rapidly.

The bulk of coronavirus research began during the SARS epidemic and through the MERS outbreak less than 10 years later. Hardly anything was known about coronaviruses at the time, Satchell said, so researchers sprinted to learn its biochemistry.

During the basic science phase of drug discovery, researchers identify the genetic sequence of a protein or enzyme that is essential to the virus replication, then look for a compound that blocks it, called the inhibitor. The compounds are developed into a drug that not only lasts long enough in the body to kill the virus but is also nontoxic. Only then can it move to animal trials.

Mesecar spent years studying SARS, then MERS. But as the outbreaks waned, funding dried up. To continue their work, his team scoured for small amounts of funding, but even three years ago, they didnt have enough to support a single person fully. Then the center at Northwestern stepped in.

But the lull in funding had already done its damage, Satchell said. No clinical trials of the compounds had been done by the time the pandemic hit. Nothing ever got out of the laboratory (for SARS), she said. Theres no treatment for COVID-19 that is specific to this virus and this infection, and the research tracking it really seems like it just ended.

When MERS emerged in 2012, Mesecars team switched to this new coronavirus, publishing papers that shared their discovery of compounds that worked against it. He and his team were among the first to predict that the next coronavirus outbreak would come from bats, the suspected origin of COVID-19. Everything we did was to predict the next outbreak, he said. What we wanted to do was to have compounds that could rapidly move toward the particular coronavirus strain that emerged.

Satchell, Mesecar and others point to earlier failings as a cautionary tale. Mesecar said researchers should study the effects of certain compounds on animals so they could be more quickly developed when new viruses appear. This was the key to remdesivir reaching patients now. Were not as far behind as we could be because of the love and ingenuity of scientists who want to pursue and learn about it, he said.

The coronavirus field is undergoing a rapid change. Satchell said, more funding will be needed and more scientists will need to remain in the field. Shes seen this effect with tuberculosis, anthrax attacks and SARS, and she believes this pandemic will yield similar results. In order to be prepared for the next public health threat, she said, scientists will need to break new ground.

You can make a lot of movement fast, based on what you know, Satchell said. But at some point, you hit a wall where you have to discover new things.

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What scientists are learning to try to be ready for what's after COVID-19 - Minneapolis Star Tribune

Biochemistry

COVID-19 Outbreak Bestows Lucrative Opportunities to Biochemistry Analysers Market; Demand to Remain High Post Pandemic – 3rd Watch News

The report on the Biochemistry Analysers market provides a birds eye view of the current proceeding within the Biochemistry Analysers market. Further, the report also takes into account the impact of the novel COVID-19 pandemic on the Biochemistry Analysers market and offers a clear assessment of the projected market fluctuations during the forecast period. The different factors that are likely to impact the overall dynamics of the Biochemistry Analysers market over the forecast period (2019-2029) including the current trends, growth opportunities, restraining factors, and more are discussed in detail in the market study.

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Some of the Major Highlights of TOC covers:

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COVID-19 Outbreak Bestows Lucrative Opportunities to Biochemistry Analysers Market; Demand to Remain High Post Pandemic - 3rd Watch News

Biochemistry

How Coronavirus Pandemic Will Impact Biochemistry Analysers Market 2019 Players, Size, CAGR, Applications, Types, Analysis, Trends, Forecast to 2025 -…

The report on the Biochemistry Analysers market provides a birds eye view of the current proceeding within the Biochemistry Analysers market. Further, the report also takes into account the impact of the novel COVID-19 pandemic on the Biochemistry Analysers market and offers a clear assessment of the projected market fluctuations during the forecast period. The different factors that are likely to impact the overall dynamics of the Biochemistry Analysers market over the forecast period (2019-2029) including the current trends, growth opportunities, restraining factors, and more are discussed in detail in the market study.

For top companies in United States, European Union and China, this report investigates and analyzes the production, value, price, market share and growth rate for the top manufacturers, key data from 2019 to 2025.

The Biochemistry Analysers market report firstly introduced the basics: definitions, classifications, applications and market overview; product specifications; manufacturing processes; cost structures, raw materials and so on. Then it analyzed the worlds main region market conditions, including the product price, profit, capacity, production, supply, demand and market growth rate and forecast etc. In the end, the Biochemistry Analysers market report introduced new project SWOT analysis, investment feasibility analysis, and investment return analysis.

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The major players profiled in this Biochemistry Analysers market report include:

Market: Drivers and RestrainsThe research report has incorporated the analysis of different factors that augment the markets growth. It constitutes trends, restraints, and drivers that transform the market in either a positive or negative manner. This section also provides the scope of different segments and applications that can potentially influence the market in the future. The detailed information is based on current trends and historic milestones. This section also provides an analysis of the volume of sales about the global market and also about each type from 2015 to 2026. This section mentions the volume of sales by region from 2015 to 2026. Pricing analysis is included in the report according to each type from the year 2015 to 2026, manufacturer from 2015 to 2020, region from 2015 to 2020, and global price from 2015 to 2026.A thorough evaluation of the restrains included in the report portrays the contrast to drivers and gives room for strategic planning. Factors that overshadow the market growth are pivotal as they can be understood to devise different bends for getting hold of the lucrative opportunities that are present in the ever-growing market. Additionally, insights into market experts opinions have been taken to understand the market better.Global Biochemistry Analysers Market: Segment Analysis The research report includes specific segments such as application and product type. Each type provides information about the sales during the forecast period of 2015 to 2026. The application segment also provides revenue by volume and sales during the forecast period of 2015 to 2026. Understanding the segments helps in identifying the importance of different factors that aid the market growth.Global Biochemistry Analysers Market: Regional AnalysisThe research report includes a detailed study of regions of North America, Europe, China and Japan. The report has been curated after observing and studying various factors that determine regional growth such as economic, environmental, social, technological, and political status of the particular region. Analysts have studied the data of revenue, sales, and manufacturers of each region. This section analyses region-wise revenue and volume for the forecast period of 2015 to 2026. These analyses will help the reader to understand the potential worth of investment in a particular region.Global Biochemistry Analysers Market: Competitive LandscapeThis section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and sales by manufacturers during the forecast period of 2015 to 2019.Following are the segments covered by the report are:Fully Automated Biochemistry AnalyserSemi Automated Biochemistry AnalyserBy Application:Hospital and Diagnostic LaboratoriesHome CareAcademic and Research InstitutesKey Players:The Key manufacturers that are operating in the global Biochemistry Analysers market are:Thermo Fisher ScientificAbbottHORIBASiemens HealthcareXylem AnalyticsAgappe DiagnosticsRMSMicroLab InstrumentsLabindia InstrumentsCompetitive LandscapeThe analysts have provided a comprehensive analysis of the competitive landscape of the global Biochemistry Analysers market with the company market structure and market share analysis of the top players. The innovative trends and developments, mergers and acquisitions, product portfolio, and new product innovation to provide a dashboard view of the market, ultimately providing the readers accurate measure of the current market developments, business strategies, and key financials.

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How Coronavirus Pandemic Will Impact Biochemistry Analysers Market 2019 Players, Size, CAGR, Applications, Types, Analysis, Trends, Forecast to 2025 -...

Biochemistry

Ground-breaking antibody test for coronavirus to be provided in Lancashire within next two weeks – Lancashire Telegraph

Ground-breaking testing for Covid-19 antibody is set to start at a Lancashire hospital within the next two weeks.

At the beginning of April, the pathology team at Lancashire Teaching Hospitals set up what is known as a PCR test on swabs taken from people with symptoms of Covid-19 to see whether or not they actually have the virus.

As a result of the test's success, the team has now been asked to set up a ground-breaking Covid-19 antibody testing facility at Royal Preston Hospital.

The new antibody test will tell pathologists whether or not a person has had the disease, and give them an understanding of how many of the population have actually been infected, in order to assist in the nationwide track and trace initiative.

The test will be performed in the clinical biochemistry laboratory at the Royal Preston Hospital, using the Roche Covid-19 antibody test.

Dr David Orr, clinical director of pathology and consultant microbiologist said: "This news is most welcome and Lancashire Teaching Hospitals is now at the forefront of measuring both the active disease using the PCR swab test and the antibody test.

"Having both of these tests available will help us in our fight to beat Covid-19."

Eventually, many labs in the country with Roche equipment will use the test, however, the lab at Preston is only one of four laboratories that have been initially chosen, mainly because it's one of the most highly advanced automated clinical biochemistry laboratories in England, supported by state of the art informatics and operated by highly skilled scientists.

The testing will require the collaboration and teamwork of many departments within Lancashire Teaching Hospitals NHS Foundation Trust, working together to carry out the test, process the samples, analyse the findings, collate the results and report on the data.

Consultant clinical biochemist at Lancashire Teaching Hospitals, Dr Martin Myers, said: "I am delighted that the clinical biochemistry department has been chosen to be in Phase One for antibody testing in England.

"Our advanced automation will allow us to perform thousands of tests a day.

"The team work between the clinical biochemists and microbiologists will have a major impact in our fight against this wretched disease and once we have carried out some quality checks, it is hoped that we will start to prove the service within two weeks."

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Ground-breaking antibody test for coronavirus to be provided in Lancashire within next two weeks - Lancashire Telegraph

Biochemistry

Weekly Briefing from the Chancellor | Newsroom – UC Merced University News

Re: Weekly Briefing from the Chancellor

To: Faculty, staff, students and parents

May 22, 2020

Dear Campus Community,

Fiat Lux let there be light. The University of California motto, emblazoned on our logo and various places around campus, holds more meaning for me now than ever. In the midst of the trials and uncertainty we have faced as a result of COVID-19, UC Merced and her sister campuses have shone a light to our communities, to our state and to the world.

As Regent John A. Prez recounted in his remarks at the UC Board of Regents meeting earlier this week, UC campuses all over the state are stepping up to create innovative solutions to the major challenges facing us in this moment. At UC Berkeley, biochemistry students are manufacturing hand sanitizer for first responders. At UCSF, medical personnel have volunteered to go to New York and the Navajo Nation to assist health care workers. At UCSB and UCSD, engineers are designing and 3-D printing face shields and ventilators.

Here at UC Merced, our own public health and engineering professors are leading critical research on telehealth for low-income Californians, a low-cost and user-friendly sanitizer, a new means of rapid COVID-19 antibody detection and risk assessment of SARS-CoV-2 in wastewater for vulnerable populations.

Beyond these groundbreaking faculty contributions, frontline staff have also stepped up to serve the more than 200 students who were not able to return home to loved ones. Many thanks to these colleagues for supporting our scholars who stayed on campus to brave the storm.

As you know, Dr. Juan Snchez Muoz was nominated by President Janet Napolitano and unanimously appointed UC Merceds fourth chancellor by the Board of Regents on Wednesday. As I have grown to intimately know and love the UC Merced community over the past year, I am certain the regents selected a perfect leader for this unique and burgeoning campus. I look forward to working with Dr. Muoz during this transition, and formally welcoming him into his new role in early July.

In his acceptance remarks, Dr. Muoz expressed a deep commitment to a centuries-old promise that the UC system would be of the people and for the people and we will continue to live those values here at UC Merced. Our People First Workgroup is a testimony to that very promise, as it works to ensure our response to COVID-19 and our eventual return to campus is guided by the vital principle of putting our people our staff, faculty, and students first.

Its also important to note that the regents, after a very long and robust debate about equity, made a decision that will have ripple effects across the country and far into the future: The UC will suspend the requirement for SAT/ACT tests for admission through 2024, and in 2025 we will either have designed our own standardized test or eliminate the use of tests entirely in admissions decisions. The implications for current and future undergraduate admissions will be significant, potentially opening up the possibility of a UC education to an even broader swath of young people.

Finally, I want to express congratulations once more to the graduates of 2020 the first class in UC Merceds history to graduate virtually. Our newest alumni took our new normal in stride and with an outpouring of joy that illuminated our digital landscape and brightened our week. Though the road they have before them is uncertain, the resourcefulness and grace with which they pivoted during this crisis will always light their path.

Fiat Lux . Let our light shine brightly as we all continue our journeys.

#BobcatStrong

Nathan Brostrom

Interim Chancellor

This is an important message from UC Merced. Please share with colleagues who may not have ready access to email. If you require a Spanish translation, please email pr@ucmerced.edu .

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Weekly Briefing from the Chancellor | Newsroom - UC Merced University News