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Anatomy

New UN report outlines the ‘Anatomy of a Genocide’ in Gaza – Mondoweiss

Last week, the UN Special Rapporteur on Occupied Palestinian Territories Francesca Albanese issued a report titled Anatomy of a Genocide, concluding that there are reasonable grounds to believe that the threshold indicating the commission of the crime of genocide has been met.

Such reports are not usually titled, but the title itself depicts the nature of what Albanese describes in her immaculate 25-page report. It not only outlines a textbook case of genocide, with clearly and widely expressed intent by leaders backed up by clear genocidal actions it also describes how Israel has used the language and principles of International Humanitarian Law (IHL, the laws governing warfare) to conceal the act.

Albanese begins with the historical context of the genocide, even rooted in Israeli pre-state colonialist intents, and then charts out how Israel has committed three central facets under the crime of genocide the killing of members of a particular group of people, causing bodily or mental harm, and creating destructive conditions of life. There is also a section concerning intent that chronicles some of the countless, unambiguous, genocidal expressions of Israeli leaders.

Then, midway into the report, and constituting almost half of it (points 55-92, out of 97 points), is a section dedicated to the idea of Humanitarian camouflage: distorting the laws of war to conceal genocidal intent.

This section is subdivided into five central themes:

Albanese demonstrates how the three central principles of IHL distinction, proportionality, and precaution have been subverted by Israel in an attempt to obfuscate its genocidal acts and to provide a legal veil for illegal, indiscriminate acts.

This has obscured one cardinal tenet of IHL, Albanese writes. Indiscriminate attacks, which do not distinguish military targets from protected persons and objects, cannot be proportionate and are always unlawful.

Palestinians have become decivilianized in this way:

A core feature of Israels conduct since 7 October has been the intensification of its de-civilianization of Palestinians, a protected group under the [Genocide] Convention. Israel has used IHL terminology to justify its systematic use of lethal violence against Palestinian civilians as a group and the extensive destruction of life-sustaining infrastructures. Israel has done this by deploying IHL concepts such as human shields, collateral damage, safe zones, evacuations and medical protection in such a permissive manner so as to gut these concepts of their normative content, subverting their protective purpose and ultimately eroding the distinction between civilians and combatants in Israeli actions in Gaza.

It is chilling to think that Israels Defense Ministers claim that we are dealing with human animals and we will act accordingly (October 9), has translated into reality in such a way that humans are reduced to conceptual rubble dehumanized and decivilainized.

The analysis continues to outline Israels subversion of IHL norms, including concepts like human shields, military objectives, and collateral damage.

The history of the general usage of this term as a pretext for indiscriminate attacks is mentioned, particularly in the 2008-2022 aggressions. But on October 7 this rose to a new level:

After 7 October, this macro-characterization of Gazas civilians as a population of human shields has reached unprecedented levels, with Israels top-ranking political and military leaders consistently framing civilians as either Hamas operatives, accomplices, or human shields among whom Hamas is embedded International law does not permit the blanket claim that an opposing force is using the entire population as human shields en bloc The accusation of using human shields has thus become a pretext, justifying the killing of civilians under a cloak of purported legality, whose all-enveloping pervasiveness admits only of genocidal intent.

International law stipulates that attacks must be strictly limited to objects that must offer a definite military advantage. But, Albanese notes, Israel has misused this rule to militarize civilian objects and whatever surrounds them, justifying their indiscriminate destruction. Thus, Gazas civilian population and infrastructure are presented as obstructions positioned amongst, in front of and above targets Israel has characterized the whole territory as a military objective Israel considers any object that has allegedly been or might be used militarily as a legitimate target, so that entire neighbourhoods can be razed or demolished under fictions of legality.

Israel seeks to conceal the widescale targeting of civilians as collateral damage. Invoking the concept of proportionate collateral damage to knowingly shell large numbers of members of the protected group, Israel asserts that when attacks result in more collateral damage than expected, this does not necessarily indicate a violation, since compliance is conduct-oriented, not result-oriented.In other words, Israel says that it doesnt mean to kill many civilians it just occurs despite precautions. However, Albanese writes,

in all attacks launched against residential towers without warnings, extensive civilian harm has been anticipated as the main outcome. The Al-Taj building was full of families at the time of the 31 October strike, which must have been anticipated as certainly killing or injuring all the civilians living there. The fact that so many people were killed was entirely predictable hence at least indirectly intended as is evident from the images that the Israeli military itself published. The attack on the Jabalia refugee camp on 25 October killed at least 126 civilians, including 69 children, and injured a further 280. Israeli military personnel affirmed that the target was one Hamas commander in an underground base.

Israel seems to assess proportionality not only as a question of military advantage but as a question of destroying Hamas politically:

Israels proportionality assessments have flouted legal requirements by defining military advantage, in each attack, in relation to the destruction of the whole Hamas organization both politically and militarily. It is manifestly illegal to declare as a war aim the destruction of the other sides political capacity (particularly in the context of a 56-year military occupation which deprives the occupied population of its right to self-determination) In other words, Israel appears to represent itself as conducting a proportionate genocide.

Albanese writes:

The mass evacuation order of 13 October when 1.1 million Palestinians were ordered to evacuate northern Gaza in 24 hours to Israeli-designated safe zones in the south Instead of increasing safety for civilians, the sheer scale of evacuations amidst an intense bombing campaign, and the haphazardly communicated safe zones system, along with extended communications blackouts, increased levels of panic, forced displacement and mass killing.

When the northern residents were evacuated to the south, Israel illegally categorized the inhabitants of northern Gaza who had remained (including the sick and wounded) as human shields and accomplices of terrorism, thereby turning hundreds of thousands of civilians into legitimate military targets or collateral casualties through impossible-to-follow evacuation orders.

And the safe zones werent safe either:

The erasure of civilian protections in the evacuated area was combined with indiscriminate targeting of evacuees and inhabitants of the areas designated as safe zones Of the roughly 500 2,000-pound bombs dropped by Israel in the first six weeks of hostilities, 42 percent were deployed in the designated safe zones in southern areas.

Simply put, Albanese summarizes, safe areas were deliberately turned into areas of mass killing.

This has been a tool of ethnic cleansing:

The pattern of killings of civilians who evacuated to the south, in combination with statements of some senior Israelis declaring an intent to forcibly displace Palestinians outside Gaza and replace them with Israeli settlers, lead to reasonably infer that evacuation orders and safe zones have been used as genocidal tools to achieve ethnic cleansing.

This point sends a chill down the spine, as Gazas largest hospital, al-Shifa has now been reduced to burned rubble, with bodies strewn across the area, following Israels recent two-week-long siege.

A final layer of Israels humanitarian camouflage concerns its efforts to provide legal cover for systematic attacks against medical facilities and personnel, causing the progressive collapse of Gazas healthcare sector, writes Albanese.

This is not the first time Israel accused Hamas of using hospitals as Hamas headquarters, but in the current assault, Israel has invoked this legal strategy to justify genocide through the complete destruction of life-sustaining infrastructure.

Israel was widely challenged on its former assault on the al-Shifa hospital in November.

Media reports challenged Israels allegations that Hamas were using hospitals as shields, asserting that there was no evidence to suggest that the rooms connected to the hospital had been used by Hamas; the hospital buildings (contrary to Israeli military 3D images) were found not to be connected to the tunnel network; and there was no evidence that the tunnels were accessible from the hospital wards. In addition, the Israeli army reportedly rearranged weaponry at al-Shifa before news crews visits, raising further suspicions of fabrication after the Israeli army had claimed that a list of terrorists it had found in another Gaza hospitalthe Al Rantisiturned out to be a calendar of the days of the week in Arabic.

The level of the Israeli propaganda would be something to laugh about (and was widely mocked) if it werent so deadly serious. Even if one were to take these repeated allegations at face value, Israel behaved illegally:

Whether or not Israels accusations of hospital shielding at al-Shifa were true but still remain to be proven , the civilians in the hospitals should have been protected and not subjected to siege and military attack.

This lack of protection for civilians was itself genocidal:

That the intent behind Israels humanitarian camouflage in this instance can only be characterized as genocidal is clear for two reasons. First, Israel was aware of the large-scale destruction of the healthcare system since the World Health Organization had reported in mid-November that a public health catastrophe was developing in Gaza, with 26 of 35 hospitals no longer operational due to Israels bombing and siege. Second, Israel knew that its military operation was resulting in a significant number of wounded. Physical trauma constitutes the most predominant cause of excess mortality in Gaza. It was predictable that forcibly suspending services at the largest hospital in Gaza would seriously harm the prospects for survival of the injured, the chronically ill and newborn babies in incubators. Therefore, by targeting al-Shifa Hospital, Israel knowingly condemned thousands of sick and displaced people to preventable suffering and death.

The overwhelming nature and scale of Israels assault on Gaza and the destructive conditions of life it has inflicted reveal an intent to physically destroy Palestinians as a group, Albanese concludes.

Israel has sought to conceal its eliminationist conduct of hostilities sanctioning the commission of international crimes as IHL-abiding. Distorting IHL customary rules, including distinction, proportionality and precautions, Israel has de facto treated an entire protected group and its life-sustaining infrastructure as terrorist or terrorist-supporting, thus transforming everything and everyone into either a target or collateral damage, hence killable or destroyable.

This goes back to the first Nakba of 1948:

Israels genocide on the Palestinians in Gaza is an escalatory stage of a long-standing settler colonial process of erasure. For over seven decades this process has suffocated the Palestinian people as a group demographically, culturally, economically and politically , seeking to displace it and expropriate and control its land and resources. The ongoing Nakba must be stopped and remedied once and for all. This is an imperative owed to the victims of this highly preventable tragedy, and to future generations in that land.

The last two points (96-97) of the report are about what we the international community can, and indeed must do, to avert this genocide.

The Special Rapporteur urges member states to enforce the prohibition of genocide in accordance with their non-derogable obligations. Israel and those states that have been complicit in what can be reasonably concluded to constitute genocide must be held accountable and deliver reparations commensurate with the destruction, death and harm inflicted on the Palestinian people.

The means at our disposal:

Finally, Albanese calls on the Office of the High Commissioner for Human Rights to enhance its efforts to end the current atrocities in Gaza, including by promoting and accurately applying International Law, notably the Genocide Convention, in the context of the oPt as a whole. That is, to see the genocide of Gaza not merely as a local matter, but as a genocidal assault on all Palestinians, also beyond Gazas geographical confines.

Israels initial, knee-jerk response was to describe the report as an obscene inversion of reality. The problem is, that Albanese has used about half of her meticulous report to document how it is precisely Israel that is inverting reality through the mentioned twisting of IHL terms to justify and continue its genocide.

The U.S., for its part, chose to avoid the subject by shooting the messenger hiding behind regurgitated, false allegations of Albanese as an antisemite as State Department Spokesperson Matthew Miller did in response to a question on the matter:

We have for a longstanding period of time opposed the mandate of this Special Rapporteur, which we believe is not productive. And when it comes to the individual that holds that position, I cant help but note a history of antisemitic comments that she has made, that were reported.

But many other countries, particularly Arab ones as well as other global south countries, rallied behind Albanese and affirmed the seriousness of her report. At the UN presentation of the report last week, Israel and the U.S. boycotted the event. The EU, for its part, called for proper and independent investigations on all allegations, alas recognizing Israels right to self-defense.

Self-defense, it bears mention, is no excuse for genocide, and the reason why one purportedly goes to war has no bearing on how one conducts it. So the EU is avoiding the issue, in a perhaps less visible manner than Israel and the U.S.

Israel has destroyed Gaza, said the Special Rapporteur. Its not incidental, its not a natural disaster its genocide. Now its only down to those who accept this awful truth and those who hide from it.

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New UN report outlines the 'Anatomy of a Genocide' in Gaza - Mondoweiss

Dermatology

Dr. Hillary Johnson-Jahangir of Forefront Dermatology Designated as a Candela Center of Excellence – PR Newswire

CORALVILLE, Iowa, April 3, 2024 /PRNewswire/ --Candela Corporation announced today that it is partnering with Dr. Hillary Johnson-Jahangir of Forefront Dermatology Laser and Surgery Center in Coralville, Iowa as a new Candela Center of Excellence.

Forefront Dermatology joins this prestigious community of clinics across the country that are designated as Candela Centers of Excellence for their commitment to the practice and teaching of medical aesthetics using Candela's portfolio of energy-based devices.

Hillary Johnson-Jahangir, MD, PhD, MS, FAAD, FACMS, is a board-certified dermatologist and board-certified and fellowship trained Mohs micrographic skin cancer surgeon with over 15 years of experience. She is the founding director of the Forefront Dermatology Laser and Surgery Center. Specializing in the treatment and prevention of skin cancer, Dr. Johnson offers advanced laser care and has extensive experience with the GentleMax Pro, Vbeam, Nordlys, PicoWay, and CO2RE systems.

Dr. Johnson is a longstanding member of theAmerican Society for Laser Medicine and Surgery. Her aesthetic sensibility was honed by years of training and practice in New York City where she was Director of Dermatologic Surgery at Weill Cornell Medical Center. Dr. Johnson also practiced laser and surgical dermatology at the University of Iowa for 7 years where she received awards for teaching and making a difference in patient care.

Dr. Johnson has been recognized as an Iowa Medical Society Women in Medicine Month Leader and an Inspirational Leader by the American Medical Association Women Physicians Section. She is also a published author of several peer-reviewed journal articles and book chapters and has lectured at universities and national meetings of multiple medical associations.

"We are thrilled to announce our partnership with Dr.Johnsonin establishing a Candela Center of Excellence dedicated to advancing education in energy-based devices," says Mary Trout, Chief Commercial Officer,Candela Corporation. "Dr.Johnson's commitment to excellence and innovation aligns perfectly with Candela's mission to empower professionals in the field of medical aesthetics and spread patient awareness on the benefits of energy-based device procedures. Together, we look forward to shaping the future of energy-based treatments and education, setting new clinical standards, and delivering transformative experiences for patients."

Forefront Dermatology, Candela Center of Excellence is located at: 2769 Heartland Drive, Suite 303, Coralville, IA 52241.

About Candela Corporation

Media contact: Laurel Sanderson [emailprotected]

SOURCE CANDELA

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Dr. Hillary Johnson-Jahangir of Forefront Dermatology Designated as a Candela Center of Excellence - PR Newswire

Cardiology

Beth Israel Deaconess Medical Center cardiologist to be honored by American Heart Association – American Heart Association

BOSTON The American Heart Association will present the 2024 Paul Dudley White Award to Dr. Robert E. Gerszten in recognition of his contributions to the field of cardiovascular medicine and outstanding record of mentoring the next generation of researchers, educators and health care professionals.

Dr. Gerszten is chief of the Division of Cardiovascular Medicine at Beth Israel Deaconess Medical Center and the Herman Dana Professor of Medicine at Harvard Medical School. He will receive the award at the Boston Heart and Stroke Ball on May 4.

The Paul Dudley White Award has been presented annually since 1974 to a Boston-based medical professional who has made extraordinary contributions to cardiovascular or stroke care. It is named after one of the citys most revered cardiologists, Dr. Paul Dudley White, a founder of the American Heart Association who is regarded as the father of preventive cardiology.

Dr. Gerszten was selected to receive this years award by a committee of area physicians. In choosing Dr. Gerszten, the committee praised him for his work around predicting, preventing, and treating patients with cardiovascular disease. They also credited his more than 30 years as a volunteer for the American Heart Association and his extensive record of mentorship.

Several colleagues nominated Dr. Gerszten for the award. Among them was Dr. Robert W. Yeh, a cardiologist at Beth Israel Deaconess Medical Center and the Smith Family Professor of Medicine at Harvard Medical School. In his nominating letter, Dr. Yeh commended Dr. Gerszten for dedicating his life to preventing and treating cardiovascular disease.

He has done this through his groundbreaking research, through the mentorship of multiple generations of physician scientists, through a consistent presence at the bedside caring for critically ill patients, and through his leadership of one of the countrys premier cardiovascular divisions, said Dr. Yeh. He has carried out his lifes work with honesty, integrity, professionalism, grace, good humor and relentless determination.

Dr. Gersztens contributions to the scientific community are extensive. He has played a significant role in our understanding of how metabolic issues impact cardiac health. His research has consistently been published in top scientific journals, and his laboratory has continually been funded by prestigious organizations including the National Institutes of Health.

Dr. Gerszten has also served in various volunteer roles for the American Heart Association throughout his career. This includes participating in working groups, grant review activities, and the coordination of community-based fundraising through the Beth Israel Deaconess Medical Center Boston Heart Walk team. Additionally, he has played a pivotal role in planning Scientific Sessions, an annual American Heart Association conference dedicated to highlighting the latest breakthroughs in cardiovascular research.

Dr. Gerszten is also known for being an exceptional mentor, showing an unwavering commitment to training the next generation of leaders in cardiovascular science. Colleagues credit him for fostering a collaborative work environment and for being an exemplary role model.

Over the past year of working daily with Dr. Gerszten in a leadership capacity, I have found him to represent every single humanistic quality that I might imagine distinguished Paul Dudley White, said Dr. Jennifer E. Ho, a cardiologist at Beth Israel Deaconess Medical Center and associate professor of medicine at Harvard Medical School. He cares deeply about the people around him, whether they be colleagues, trainees or patients.

Dr. Gerszten received his bachelors degree from the University of Virginia and his medical degree from Johns Hopkins University. He completed his residency at the University of Pennsylvania and his clinical fellowship in cardiology at Massachusetts General Hospital.

He lives in Brookline with his wife Elena. He is happiest while fishing off Marthas Vineyard, or even while losing to his two sons in tennis. His career has been deeply impacted by his parents, both of whom dedicated their lives to academic medicine as a physician educator and as a social worker.

The Boston Heart and Stroke Ball is a celebration of the year-round Heart of Boston campaign, which supports the American Heart Associations 2024 Health Equity Impact Goal to reduce barriers to health care access and quality. It will be held on Saturday, May 4, at the Omni Boston Hotel at the Seaport.

Dr. Gersztens commitment to the mission of the American Heart Association has been instrumental in our efforts to ensure that every person has the opportunity to live a full, healthy life, said Eric Green, chair of the Heart of Boston campaign and senior vice president and head of development programs at Alnylam Pharmaceuticals. We look forward to honoring his contributions to cardiology and health when we gather at the Heart and Stroke Ball in May.

For more information about the Heart and Stroke Ball, visit heart.org/BostonHB or contact Rachel Adjemian, associate vice president of development, at rachel.adjemian@heart.org.

###

About the American Heart Association

The American Heart Association is a relentless force for a world of longer, healthier lives. We are dedicated to ensuring equitable health in all communities. Through collaboration with numerous organizations, and powered by millions of volunteers, we fund innovative research, advocate for the publics health and share lifesaving resources. The Dallas-based organization has been a leading source of health information for nearly a century. Connect with us onheart.org,Facebook,Xor by calling 1-800-AHA-USA1.

For Media Inquiries:

Chris Camire, Marketing Communications Director

chris.camire@heart.org

For Public Inquiries:

1-800-AHA-USA1 (242-8721)

heart.org and stroke.org

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Beth Israel Deaconess Medical Center cardiologist to be honored by American Heart Association - American Heart Association

Immunology

Theratechnologies Announces Publication in Frontiers in Immunology that Deepens Understanding of Sudocetaxel … – GlobeNewswire

MONTREAL, Feb. 20, 2024 (GLOBE NEWSWIRE) -- Theratechnologies Inc. (Theratechnologies or the Company) (TSX: TH) (NASDAQ: THTX), a biopharmaceutical company focused on the development and commercialization of innovative therapies, today announced the publication of a peer-reviewed article in Frontiers in Immunology that enhances understanding of the molecular mechanism of action of sudocetaxel zendusortide (also known as TH1902) as a potential anticancer treatment. Sudocetaxel zendusortide is an investigational, first-in-class peptide-drug conjugate (PDC) that targets the sortilin receptor (SORT1) and expedites the internalization and delivery of the cytotoxic payload (docetaxel) directly into cancer cells.

The article, Sudocetaxel Zendusortide (TH1902) triggers the cGAS/STING pathway and potentiates anti-PD-L1 immune-mediated tumor cell killing appears in the Cancer Immunity and Immunotherapy section of the February (Volume 15) issue of the journal. It reports on preclinical research in which sudocetaxel zendusortide induced complete and prolonged tumor regression in a triple-negative breast cancer (TNBC)-derived xenograft tumor model and demonstrated tumor regression associated with growth inhibition and immune cell infiltration in a cold murine (syngeneic) tumor model. Additionally, combining sudocetaxel zendusortide with an anti-PD-L1 checkpoint inhibitor led to increases in tumor growth inhibition and median animal survival.

The results published in Frontiers in Immunology demonstrate that sudocetaxel zendusortide exerts its antitumor activity, in part, through modulation of the immune tumor microenvironment, said Christian Marsolais, Ph.D., Senior Vice President and Chief Medical Officer at Theratechnologies, and one of the papers co-authors. Our findings reinforce that combining this novel peptide-drug conjugate with anti-PD-L1 checkpoint inhibitor therapy may yield improved clinical outcomes, with potentially profound implications for patients across various cancer types.

An important aspect of our research is the activation of an antitumor immunity process through involvement of the cGAS/STING pathway, a key regulator in the cancer-immunity cycle, commented Prof. Borhane Annabi, Chair in Cancer Prevention and Treatment in the Chemistry Department at the Universit du Qubec Montral, and a co-author of the Frontiers in Immunology paper. Although the animal tumor model we worked with is considered a non-immunogenetic, or cold tumor model, we observed a net increase in leukocyte infiltration within sudocetaxel zendusortide-treated tumors, especially for tumor-infiltrating lymphocytes and tumor-associated macrophages. This realization supports the rationale for further exploration of the combination of sudocetaxel zendusortide with immunotherapy.

The article can be accessed online here.

About Immunotherapy in Cold and Hot Tumors

Immunotherapies have significantly improved the treatment of cancer. Researchers continue to explore the power of the immune system to find and destroy cancer cells. Hot tumors show signs of inflammation, meaning the tumor has already been infiltrated by immune cells rushing to fight the cancerous cells. Only a few types of cancers are considered to be hot. Cold tumors have not yet been infiltrated with T cells. This signals that the immune response is not working, making it difficult to provoke an immune response with immunotherapies. Most cancers of breast, ovary, prostate, pancreas, and brain (e.g., glioblastoma [GBM]) are cold tumors, and are largely treated with traditional therapies like radiation and chemotherapy. As a result, researchers have sought to understand how to turn cold tumors hot by reversing the suppressive microenvironment surrounding cold tumors and by attracting more of the right anti-tumor lymphocytes.

About Sudocetaxel Zendusortide (TH1902) and SORT1+ Technology

Sudocetaxel zendusortide is a first-of-its-kind sortilin receptor (SORT1)-targeting PDC, and the first compound to emerge from the Companys broader licensed oncology platform. As a new chemical entity, sudocetaxel zendusortide employs a cleavable linker to conjugate (attach) a proprietary peptide to docetaxel, a well-established cytotoxic chemotherapeutic agent used to treat many cancers. The FDA granted Fast Track designation to sudocetaxel zendusortide as a single agent for the treatment of all sortilin-positive recurrent advanced solid tumors that are refractory to standard therapy. Sudocetaxel zendusortide is currently being evaluated in a Phase 1 clinical trial in individuals with advanced ovarian cancer.

Theratechnologies has established the SORT1+ TechnologyTMplatform as an engine for the development of PDCs that target SORT1, which is expressed in multiple tumor types. SORT1 is a scavenger receptor that plays a significant role in protein internalization, sorting, and trafficking. Expression of SORT1 is associated with aggressive disease, poor prognosis, and decreased survival. It is estimated that SORT1 is expressed in 40% to 90% of endometrial, ovarian, colorectal, triple-negative breast (TNBC), and pancreatic cancers, making this receptor an attractive target for anticancer drug development.

About Theratechnologies

Theratechnologies (TSX: TH) (NASDAQ: THTX) is a biopharmaceutical company focused on the development and commercialization of innovative therapies addressing unmet medical needs. Further information about Theratechnologies is available on the Company's website at http://www.theratech.com, on SEDAR+ at http://www.sedarplus.caand on EDGAR at http://www.sec.gov. Follow Theratechnologies on Linkedinand X (formerly Twitter).

Forward-Looking Information

This press release contains forward-looking statements and forward-looking information (collectively, the Forward-Looking Statements) within the meaning of applicable securities laws, that are based on managements beliefs and assumptions and on information currently available to it. You can identify forward-looking statements by terms such as may, will, should, could, promising, would, outlook, believe, plan, envisage, anticipate, expect and estimate, or the negatives of these terms, or variations of them. The Forward-Looking Statements contained in this press release include, but are not limited to, statements regarding the combination of sudocetaxel zendusortide with anti-PD-L1 checkpoint inhibitor therapy which may yield improved clinical outcomes, the potential treatment of various types of cancer with sudocetaxel zendusortide, the development of PDCs resulting from the SORT1+ TechnologyTMplatform and our estimates regarding the expression of SORT1 in various types of cancer. Although the Forward-Looking Statements contained in this press release are based upon what the Company believes are reasonable assumptions in light of the information currently available, investors are cautioned against placing undue reliance on these statements since actual results may vary from the Forward-Looking Statements contained in this press release. These assumptions include, without limitation, that the results observed in pre-clinical testing will be replicated into humans, sudocetaxel zendusortide will be able to treat various types of cancer, the Company will be successful in developping addtional PDCs from the SORT1+ TechnologyTMplatform and positive safety and efficacy results will be observed from the current Phase 1 clinical trial studying sudocetaxel zendusortide. Forward-Looking Statements assumptions are subject to a number of risks and uncertainties, many of which are beyond the Companys control, that could cause actual results to differ materially from those that are disclosed in or implied by such Forward-Looking Statements. These risks and uncertainties include, but are not limited to, the inability of sudocetaxel zendusortide to demonstrate efficacy results when used in human subjects, limitations in the types of cancer for which sudocetaxel zendusortide could be used and limitations in the capacity of the Company to develop new PDCs. We refer current and potential investors to the Risk Factors section of our Annual Information Form dated February 27, 2023, available on SEDAR+ atwww.sedarplus.caand on EDGAR atwww.sec.govas an exhibit to our report on Form 40-F dated February 28, 2023, under Theratechnologies public filings. The reader is cautioned to consider these and other risks and uncertainties carefully and not to put undue reliance on forward-looking statements. Forward-Looking Statements reflect current expectations regarding future events and speak only as of the date of this press release and represent our expectations as of that date.

We undertake no obligation to update or revise the information contained in this press release, whether as a result of new information, future events or circumstances or otherwise, except as may be required by applicable law.

Contacts:

Media inquiries: Julie Schneiderman Senior Director, Communications & Corporate Affairs communications@theratech.com 1-514-336-7800

Investor inquiries: Philippe Dubuc Senior Vice President and Chief Financial Officer pdubuc@theratech.com 1-438-315-6608

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Theratechnologies Announces Publication in Frontiers in Immunology that Deepens Understanding of Sudocetaxel ... - GlobeNewswire

Emergency Medicine

Keystone Healthcare Partners Establishes Partnership with Trinity Medical to Expand Emergency Medicine Footprint … – PR Newswire

MEMPHIS, Tenn., Feb. 2, 2024 /PRNewswire/ -- Keystone Healthcare Partners (Keystone Healthcare), a leading provider of emergency medicine, hospital medicine, critical care medicine, andtelehealth staffing and management services, as well as revenue cycle management, recently announced that it has formed a partnership with Trinity Medical in Ferriday, Louisiana. Keystone's delivery of emergency medicine services at Trinity Medical will commence on February 1, 2024.

This contract represents an exciting expansion of Keystone's regional influence into Louisiana; the company has managed contracts in Mississippi for decades. Glenn Adams, Keystone's CEO & Co-founder, notes, "We are excited to kick off another partnership with a client where we see opportunity for real impact. We've hit the ground running to shore up areas of frustration for the client and bring value-add and innovative solutions, such as Keystone Connect AI technology to the emergency medicine program."

While the healthcare landscape has been challenging for rural and critical access hospitals, the two entities share a patient-centered ethos that will be paramount to the partnership. The two entities share a community- and patient-focus that is embodied by Trinity's motto, "People you know, caring for people you love."

"We are very excited to start our partnership with Keystone Healthcare," states Keisha Smith, CEO of Trinity. "My goal for Trinity Medical has always been to provide our patients with the best healthcare and customer service possible in the Miss-Lou area. We feel that Keystone shares the same goals that we have and will be a true asset to our hospital. Henry Ford stated, 'Coming together is a beginning, staying together is progress, and working together is success.' We are looking forward to a long lasting, successful partnership with Keystone Healthcare."

Trinity Medical, a 23-bed licensed facility, continues to grow and upgrade their services and facilities in addition to recruiting physicians to meet the growing needs of their expanding community.

About Keystone Healthcare

Keystone Healthcare is a leading provider of Emergency Medicine, Hospital Medicine, Critical Care Medicine and Telehealth clinical management services and staffing solutions for hospitals. We efficiently deliver high-quality, patient-centered care through strong physician leadership and involved management that drive our innovative and integrated business model.

About Trinity Medical

Trinity Medical is operated by Concordia Parish Hospital Service District No. 1. Trinity Medical, formerly Riverland Medical Center, opened in 1964 as Concordia Parish Hospital and has continuously served the residents of the area for more than 55 years.

In addition to emergency and acute care, Trinity Medical offers surgical services, diagnostic imaging, infusion center, cardio-respiratory care, gastroenterology, lab services, otolaryngology, urology, and an in-hospital rehabilitation service as well as an extensive range of out-patient services, both diagnostic and for treatment.

Media Contact: (901) 795-3600, [emailprotected].:

SOURCE Keystone Healthcare Partners

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Keystone Healthcare Partners Establishes Partnership with Trinity Medical to Expand Emergency Medicine Footprint ... - PR Newswire

Neuroscience

Lust Over Love: The Psychology and Impact of Modern Music – Neuroscience News

Summary: Over 40 years, popular music lyrics have shifted from themes of love to lust, as revealed by a study of Billboards Top 40 songs from 1971 to 2011. This analysis indicates a decline in songs featuring love or a mix of love and lust, contrasting with a rise in songs focusing solely on lust, particularly in hip-hop/rap.

These trends reflect broader cultural changes towards accepting sexuality outside traditional romantic relationships. The study also considers the impact of these lyrical themes on young listeners attitudes and behaviors towards sexuality.

Key Facts:

Source: Neuroscience News

The lyrical landscape of popular music has undergone a significant transformation over the last four decades. A meticulous analysis of Billboards Top 40 songs from 1971 to 2011 reveals an intriguing shift: the prevalence of love themes has declined, while songs focusing on lust, especially without love, have surged, particularly in the hip-hop/rap genre.

This evolution in lyrical content not only mirrors but also potentially molds societal norms, especially regarding sexuality outside of love relationships.

This research offers a novel perspective on how sexual desire (lust) and romantic desire (love) are depicted in popular music, an influential medium in shaping public consciousness, particularly among adolescents and young adults.

The findings highlight a cultural shift towards greater acceptance of sexuality outside traditional romantic contexts. The analysis, encompassing 360 songs, sheds light on the interplay between lust and love themes in music lyrics and their evolution over time.

The decrease in songs with love themes and those combining lust and love, coupled with the increase in songs emphasizing lust in the absence of love, reflects changing societal attitudes.

These trends are particularly pronounced in hip-hop/rap music, though the change transcends genres. This shift may influence cultural norms and indicate a societal move towards embracing sexuality beyond the confines of love relationships.

Adolescents and young adults, who rank mass media as a crucial source of sexual information, are heavily exposed to these themes. This exposure shapes their sexual attitudes and scripts, potentially due to their limited personal experience.

Popular music, containing more sexual content than other media directed at young people, plays a significant role in this dynamic. The high consumption of music by 8- to 18-year-olds, averaging 16 hours a week, underscores its impact.

The study also explores the portrayal of gender roles in popular music. It documents a trend towards stereotypical gender roles, with women often depicted as sexual objects for male pleasure, particularly in music videos. This portrayal varies by genre, with hip-hop and rap displaying more explicit sexual content and objectification.

Notably, the study also situates these findings within the broader context of changes in popular music over time. Since the 1960s, popular music has evolved in terms of sound, content, and themes.

This includes not just the shift in sexual content but also changes in emotional tone (like sadder-sounding music), loudness, pitch variability, and references to antisocial behavior and substance use. These changes are reflective of broader social and cultural shifts.

The studys methodology, focusing on the themes of lust and love in lyrics, offers a unique lens to understand these trends. Unlike previous research that often focused on specific sexual acts or objectifying content, this study broadly categorizes themes into expressions of sexual desire (lust) and romantic love (love).

This approach provides a clearer picture of the evolving interplay between these two themes in popular music.

One key finding is that the increase in lust-focused themes is not simply an increase in sexual content overall. Instead, it represents a shift in how sexuality is framed moving away from romantic contexts towards a more casual or non-relational approach.

This shift, particularly marked from the early 2000s, suggests a cultural trend towards normalizing sexuality outside of traditional romantic relationships.

The study also investigates potential mediators of these trends, like the gender of the artist and the musical genre. Interestingly, the gender of the artist did not significantly influence the themes of lust and love in the songs.

However, the genre had a notable impact, with hip-hop/rap featuring more lust-focused themes and less love-oriented content compared to other genres. This genre-specific trend aligns with previous findings about the portrayal of sexuality in hip-hop/rap music.

Despite these insights, the study acknowledges limitations and calls for future research. It suggests that more detailed analyses, including annual assessments and broader genre sampling, could provide a more nuanced understanding of these lyrical trends.

Additionally, it recognizes the need to explore the impact of these themes on the listeners, especially adolescents and young adults, who are most exposed to and influenced by popular music.

In conclusion, the study offers a comprehensive view of how popular music lyrics have shifted over four decades, reflecting and potentially influencing societal attitudes towards love and lust. It underscores the power of music as a cultural barometer and a medium that both mirrors and shapes public consciousness, especially in the realm of human sexuality.

Author: Neuroscience News Communications Source: Neuroscience News Contact: Neuroscience News Communications Neuroscience News Image: The image is credited to Neuroscience News

Original Research: Closed access. Love lies: A content analysis of romantic attachment style in popular music by McKell AJorgensen-Wells et al. Psychology of Music

Abstract

Love lies: A content analysis of romantic attachment style in popular music

During adolescence, music consumption drastically increases and many adolescents become romantically involved. Popular songs often depict romance, and teens may incorporate tenets of these lyrics into their own romantic experiences.

Romantic attachment style is a primary indicator of relationship functioning, and individuals attachment style may shift according to romantic experiences they observe in media.

This study comprises a content analysis of the romantic attachment style portrayed in popular song lyrics. Findings revealed that more than 86% of songs illustrated an insecure attachment and various song/artist characteristics were associated with specific attachment styles.

We assert that parents, teens, and educators should be mindful of the lyrics adolescents listen to, working together to ensure adolescents navigate musics messages about romance in a positive way.

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Lust Over Love: The Psychology and Impact of Modern Music - Neuroscience News

Neuroscience

Tackling the Poor Sleep Pandemic: FRENZ Brainband by Earable Neuroscience Announces Global Sales After CES … – PR Newswire

FRENZ Brainband, a pioneering AI-powered sleep wearable initially introduced as a prototype at CES 2023, is now available for global delivery, heralding a new era in sleep tech and digital therapeutics for home use. FRENZ was early funded by Founders Fund and Samsung Ventures.

BOULDER, Colo., Jan. 14, 2024 /PRNewswire/ -- Following its CES Innovation Award for Aging Technology, Earable Neuroscience announced the global sales of FRENZ Brainband, a groundbreaking AI-powered sleep tech wearable designed to help people sleep better. FRENZ Brainband, paired with the complimentary FRENZ AI Sleep Science app, has been clinically proven to help people fall asleep 24 minutes faster on average, as published on Nature Scientific Report. FRENZ is now ready for shipping globally from frenzband.com. The product is currently trending in the Fitness & Activity Monitors category on Amazon.

FRENZ Brainband represents a significant advancement in sleep technology, offering precise tracking and real-time brain activity stimulation using non-invasive audio therapy. Its unique comfortable design includes bone-conduction speakers and sophisticated AI algorithms to promote quicker sleep onset and longer deep sleep periods. This year, Earable showcased this revolutionary product at CES Eureka Park and was among the finalists for the CTA Foundation Pitch.

Prof. Tam Vu, Founder and CEO of Earable Neuroscience and former professor at the University of Colorado and the University of Oxford, passionately presented the Brainband at CES. "FRENZ is a comprehensive, comfortable, all-in-one sleep wearable that provides real-time, direct stimulation with precise data to effectively address sleep issues. FRENZ's science-backed audio therapies are especially beneficial for individuals who struggle to fall asleep or return to sleep after waking up at night, particularly those suffering from stress, anxiety, and running thoughts," said Vu. He highlighted the Brainband's proven efficacy in large-scale trials, with an 89% precision rate compared to the gold standard Polysomnography (PSG), and its significant impact on reducing sleep onset time.

Vu further shared, "As the CES Innovation Honoree for Aging Tech, we have received numerous accolades and interest from forward-thinking healthcare providers in the States this year. With mass production at Foxconn underway, we are poised to scale up the sleep tech market significantly. We are actively seeking strategic B2B partnerships and investments for market expansion in the healthcare and digital therapeutics space."

The Brainband is designed for a broad user base, from wellness enthusiasts to the elderly with chronic sleep issues, to those with mild sleep difficulties. It retails as a wellness device with an MSRP of $490, which includes lifetime access to the standard Fast Sleep and Back to Sleep CBT-i library. Premium content and features are anticipated for future release.

To order a FRENZ Brainband, visit http://www.frenzband.com

About Earable NeuroscienceEarable Neuroscience is a US deep tech company dedicated to delivering scalable and human-centric solutions. The FRENZ Brainband by Earable is the world's first sleep tech wearable capable of tracking and stimulating brain activities through audio therapy to promote better sleep quality.

Media Contact: [emailprotected]

Kimi Doan [emailprotected] +16178555995

SOURCE Earable Neuroscience

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Tackling the Poor Sleep Pandemic: FRENZ Brainband by Earable Neuroscience Announces Global Sales After CES ... - PR Newswire

Genetics

Myriad Genetics to Acquire Precise Tumor, Precise Liquid and Laboratory from Intermountain Precision Genomics – GlobeNewswire

SALT LAKE CITY, Jan. 18, 2024 (GLOBE NEWSWIRE) -- Myriad Genetics, Inc., (NASDAQ: MYGN), a leader in genetic testing and precision medicine, today announced it has entered into a definitive agreement to acquire select assets from Intermountain Precision Genomics (IPG) laboratory business, including the Precise Tumor Test, the Precise Liquid Test, and IPGs CLIA-certified laboratory in St. George, Utah where the Precise Tumor Test is currently performed.

The acquisition is expected to close on February 1, 2024, subject to customary closing conditions. By bringing the Precise Tumor and Precise Liquid tests in house, Myriad will open up new opportunities for innovation, growth, and continued development of its oncology portfolio.

With this acquisition, were deepening our commitment to our oncology business while also generating a more effective way to scale and grow our tumor profiling and liquid biopsy tests, including operational efficiencies, reimbursement benefits and new clinical development opportunities, said Paul J. Diaz, president and CEO, Myriad Genetics. Wed like to thank our longstanding partners at Intermountain Healthcare for the important progress theyve made in advancing precision oncology care. We look forward to continuing to build on this foundation to provide comprehensive genomic profiling options to the Intermountain Health System and its patients and providers that can help guide clinical care and improve patient outcomes.

Myriads Precise Tumor Test, which is also offered by IPG as TheraMap: Solid Tumor, analyzes a patients tumor DNA to discover and target important variants within tumors. The 500+ gene panel looks at both DNA and RNA to match patients with advanced solid tumors to the right therapy as well as identifying eligibility for clinical trials. Upon the closing of the acquisition on February 1, 2024, Myriad expects to operate TheraMap: Solid Tumor solely as Precise Tumor.

Precise Liquid, which is expected to launch later this year, will provide convenient comprehensive genomic profiling results from a blood draw. IPG has completed all validation studies to support the local coverage determination (LCD) for Precise Liquid and submitted clinical evidence of test performance in December 2023 for Medicare reimbursement.

The financial terms of the deal were not disclosed but are not material to either Myriad or Intermountain Healthcare.

About Myriad Genetics Myriad Genetics is a leading genetic testing and precision medicine company dedicated to advancing health and well-being for all. Myriad develops and offers genetic tests that help assess the risk of developing disease or disease progression and guide treatment decisions across medical specialties where genetic insights can significantly improve patient care and lower healthcare costs. For more information, visit http://www.myriad.com.

Safe Harbor Statement This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including that the acquisition is expected to close on February 1, 2024, statements relating to the expected benefits of the acquisition, including that it will open up new opportunities for innovation, growth, and continued development of the company's oncology portfolio, that the company expects to operate TheraMap: Solid Tumor as Precise Tumor upon the closing of the acquisition, and that Precise Liquid is expected to launch later this year. These forward-looking statements are managements expectations of future events as of the date hereof and are subject to known and unknown risks and uncertainties that could cause actual results, conditions, and events to differ materially and adversely from those anticipated. Such risks and uncertainties include, but are not limited to, the risk that a condition to closing of the proposed transaction may not be satisfied; that either party may terminate the definitive agreement or that the closing of the proposed transaction may be delayed or not occur at all; potential adverse reactions or changes to business or employee relationships, including those resulting from the announcement or consummation of the proposed transaction; and such other risks described in the companys filings with the U.S. Securities and Exchange Commission, including the companys Annual Report on Form 10-K filed on March 1, 2023, as well as any updates to those risk factors filed from time to time in the companys Quarterly Reports on Form 10-Q or Current Reports on Form 8-K. Myriad is not under any obligation, and it expressly disclaims any obligation, to update or alter any forward-looking statements, whether as a result of new information, future events or otherwise except as required by law.

Investor Contact Matt Scalo (801) 584-3532 IR@myriad.com

Media Contact Glenn Farrell (385) 318-3718 PR@myriad.com

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Myriad Genetics to Acquire Precise Tumor, Precise Liquid and Laboratory from Intermountain Precision Genomics - GlobeNewswire

Biology

Synthetic biology aims to tackle disease and give cells superpowers – Science News Explores

activate: (in biology) To turn on, as with a gene or chemical reaction.

amino acids: Simple molecules that occur naturally in plant and animal tissues and that are the basic building blocks of proteins.

antenna: (plural: antennae or antennas) In biology: Either of a pair of long, thin sensory appendages on the heads of insects, crustaceans and some other arthropods. (in physics) Devices for picking up (receiving) electromagnetic energy.

artery: Part of the bodys circulation system. There are several. Each is amajor tuberunning between the heart and blood vessels that will move blood to all parts of the body.

behavior: The way something, often a person or other organism, acts towards others, or conducts itself.

biology: The study of living things. The scientists who study them are known as biologists.

blood vessel: A tubular structure that carries blood through the tissues and organs.

cancer: Any of more than 100 different diseases, each characterized by the rapid, uncontrolled growth of abnormal cells. The development and growth of cancers, also known as malignancies, can lead to tumors, pain and death.

carbon: A chemical element that is the physical basis of all life on Earth. It can self-bond, chemically, to form an enormous number of chemically, biologically and commercially important molecules.

carbon nanotube: A nanoscale, tube-shaped material, made from carbon that conducts heat and electricity well.

cardiologist: A doctor that specializes in the branch of medicine dealing with functions and diseases of the heart.

cell: (in biology) The smallest structural and functional unit of an organism. Typically too small to see with the unaided eye, it consists of a watery fluid surrounded by a membrane or wall. Depending on their size, animals are made of anywhere from thousands to trillions of cells.

cell membrane: A structure that separates the inside of a cell from what is outside of it. Some particles are permitted to pass through the membrane.

chain reaction: An event that once started continues to keep itself going. Its a term frequently used to describe atomic fission in a nuclear power plant. By packing enough fuel closely enough together, neutrons released by fissioning atoms bombard neighboring atoms, inducing them to fission. This sets up a self-sustaining process.

chemical: A substance formed from two or more atoms that unite (bond) in a fixed proportion and structure. For example, water is a chemical made when two hydrogen atoms bond to one oxygen atom. Its chemical formula is H2O. Chemical also can be an adjective to describe properties of materials that are the result of various reactions between different compounds.

chemical signal: A message made up of molecules that get sent from one place to another. Bacteria and some animals use these signals to communicate.

chemistry: The field of science that deals with the composition, structure and properties of substances and how they interact.

cholesterol: A fatty material in animals that forms a part of cell walls. In vertebrate animals, it travels through the blood in little vessels known as lipoproteins. Excessive levels in the blood can signal risks to blood vessels and heart.

clot: (in medicine) A collection of blood cells (platelets) and chemicals that collect in a small region, stopping the flow of blood.

conductive: Able to carry an electric current.

contract: To activate muscle by allowing filaments in the muscle cells to connect. The muscle becomes more rigid as a result.

current: (in electricity) The flow of electricity or the amount of charge moving through some material over a particular period of time.

defense: (in biology) A natural protective action taken or chemical response that occurs when a species confronts predators or agents that might harm it. (adj. defensive)

DNA: (short for deoxyribonucleic acid) A long, double-stranded and spiral-shaped molecule inside most living cells that carries genetic instructions. It is built on a backbone of phosphorus, oxygen, and carbon atoms. In all living things, from plants and animals to microbes, these instructions tell cells which molecules to make.

electricity: A flow of charge, usually from the movement of negatively charged particles, called electrons.

electrode: A device that conducts electricity and is used to make contact with non-metal part of an electrical circuit, or that contacts something through which an electrical signal moves. (in electronics)Part of a semiconductor device (such as a transistor) that either releases or collects electronsor holes, or that can controltheir movement.

engineer: A person who uses science and math to solve problems. As a verb, to engineer means to design a device, material or process that will solve some problem or unmet need.

generation: A group of individuals (in any species) born at about the same time or that are regarded as a single group. Your parents belong to one generation of your family, for example, and your grandparents to another. Similarly, you and everyone within a few years of your age across the planet are referred to as belonging to a particular generation of humans.

germ: Any one-celled microorganism, such as a bacterium orfungal species, or a virus particle. Some germs cause disease. Others can promote the health of more complex organisms, including birds and mammals. The health effects of most germs, however, remain unknown.

immune: (adj.) Having to do with immunity. (v.) Able to ward off a particular infection.

immune system: The collection of cells and their responses that help the body fight off infections and deal with foreign substances that may provoke allergies.

implant: A device manufactured to replace a missing biological structure, to support a damaged biological structure, or to enhance an existing biological structure. Examples include artificial hips, knees and teeth; pacemakers; and the insulin pumps used to treat diabetes.Or some device installed surgically into an animals body to collect information on the individual (such as its temperature, blood pressure or activity cycle).

infectious: An adjective that describes a type of microbe or virus that can be transmitted to people, animals or other living things.

limb: (in physiology) An arm or leg. (in botany) A large structural part of a tree that branches out from the trunk.

link: A connection between two people or things.

magnetic field: An area of influence created by certain materials, called magnets, or by the movement of electric charges.

membrane: A barrier which blocks the passage (or flow through) of some materials depending on their size or other features. Membranes are an integral part of filtration systems. Many serve that same function as the outer covering of cells or organs of a body.

molecule: An electrically neutral group of atoms that represents the smallest possible amount of a chemical compound. Molecules can be made of single types of atoms or of different types. For example, the oxygen in the air is made of two oxygen atoms (O2), but water is made of two hydrogen atoms and one oxygen atom (H2O).

muscle: A type of tissue used to produce movement by contracting its cells, known as muscle fibers. Muscle is rich in protein, which is why predatory species seek prey containing lots of this tissue.

nanoparticle: A small particle with dimensions measured in billionths of a meter.

nerve: A long, delicate fiberthat transmits signalsacross the body of an animal. An animals backbone contains many nerves, some of which control the movement of its legs or fins, and some of which convey sensations such as hot, cold or pain.

network: A group of interconnected people or things. (v.) The act of connecting with other people who work in a given area or do similar thing (such as artists, business leaders or medical-support groups), often by going to gatherings where such people would be expected, and then chatting them up. (n. networking)

novel: Something that is clever or unusual and new, as in never seen before.

organ: (in biology) Various parts of an organism that perform one or more particular functions. For instance, an ovary is an organ that makes eggs, the brain is an organ that makes sense of nerve signals and a plants roots are organs that take in nutrients and moisture.

organism: Any living thing, from elephants and plants to bacteria and other types of single-celled life.

particle: A minute amount of something.

pH: A measure of a solutions acidity or alkalinity. A pH of 7 is perfectly neutral. Acids have a pH lower than 7; the farther from 7, the stronger the acid. Alkaline solutions, called bases, have a pH higher than 7; again, the farther above 7, the stronger the base.

plaque: An accumulation of materials in the body from the fluids that move through an area or bathe it. They can be minerals, proteins or other substances that collect as deposits. (in heart disease) Fatty deposits that accumulate in vessels as a result of a disease known as atherosclerosis. This plaque is made up of fat, cholesteroland other substances carried by the blood. Eventually these deposits will harden and narrow the internal openings of the arteries. This reduces the flow of oxygen and blood to organs throughout body.

podcast: A digital audio or video series that can be downloaded from the Internet to your computer or smartphone. Some podcasts also are shows that are broadcast on radio, television or other media.

pore: A tiny hole in a surface. On the skin, substances such as oil, water and sweat pass through these openings.

prosthetic: Adjective that refers to a prosthesis.

protein: A compound made from one or more long chains of amino acids. Proteins are an essential part of all living organisms. They form the basis of living cells, muscle and tissues; they also do the work inside of cells. Antibodies, hemoglobin and enzymes are all examples of proteins. Medicines frequently work by latching onto proteins.

retinitis pigmentosa: Also known as RP, this incurable family of genetic eye diseases causes cells in the retina light-sensitive tissue at the back of the eyeball to fail. Problems emerge in childhood. Most patients eventually go blind.

rhodopsin: A pigment molecule bound to the light-sensing protein opsin. Rhodopsins are found in red cells of the eye. They are extremely sensitive to light, but cannot sense color.

risk: The chance or mathematical likelihood that some bad thing might happen. For instance, exposure to radiation poses a risk of cancer. Or the hazard or peril itself. (For instance: Among cancer risks that the people faced were radiation and drinking water tainted with arsenic.)

science fiction: A field of literary or filmed stories that take place against a backdrop of fantasy, usually based on speculations about how science and engineering will direct developments in the distant future. The plots in many of these stories focus on space travel, exaggerated changes attributed to evolution or life in (or on) alien worlds.

strategy: A thoughtful and clever plan for achieving some difficult or challenging goal.

synthetic: An adjective that describes something that did not arise naturally, but was instead created by people. Many synthetic materialshave been developed to stand in for natural materials, such as synthetic rubber, synthetic diamond or a synthetic hormone. Some may even have a chemical makeup and structure identical to the original.

synthetic biology: A research field in which scientists work on developing custom life forms in the lab. Because they make synthetic organisms, scientists who work in this field are known as synthetic biologists.

system: A network of parts that together work to achieve some function. For instance, the blood, vessels and heart are primary components of the human body's circulatory system. Similarly, trains, platforms, tracks, roadway signals and overpasses are among the potential components of a nation's railway system. System can even be applied to the processes or ideas that are part of some method or ordered set of procedures for getting a task done.

technology: The application of scientific knowledge for practical purposes, especially in industry or the devices, processes and systems that result from those efforts.

tissue: Made of cells, it is any of the distinct types of materials that make up animals, plants or fungi. Cells within a tissue work as a unit to perform a particular function in living organisms. Different organs of the human body, for instance, often are made from many different types of tissues.

wave: A disturbance or variation that travels through space and matter in a regular, oscillating fashion.

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Synthetic biology aims to tackle disease and give cells superpowers - Science News Explores

Genetics

Raha Kapoor’s blue eyes remind fans of her great-grandfather, Raj Kapoor; here’s what genetics says – IndiaTimes

It's already been a day since Raha Kapoor's pap debut, and the internet can not stop gushing over the youngest member of the Kapoor clan. Born on November 6, 2022, to actors Ranbir Kapoor and Alia Bhatt, Raha was always kept away from the limelight by her parents. On Christmas Day, the family of three posed before the media and everyone got the first look of the youngest Kapoor. Raha can also be seen in the Christmas celebration pics of the Kapoors. Fans remember Rishi Kapoor, Ranbir's dad after seeing her. Social media is flooded with pictures comparing Raha with Raj Kapoor, Rishi Kapoor and Shashi Kapoor. But what has caught the attention of all is her eyes. Seems she has acquired the most distinguishable and desired genes of the Kapoor lineage. Yes, blue eyes are an inherited trait, and the color of a person's eyes is determined by the interplay of genetics. Eye color is primarily influenced by the amount and type of pigments in the front part of the iris, the colored part of the eye. Ultimate tips for moms only from Twinkle Khanna The color of the eyes is determined by multiple genes, with the two main types of pigments being melanin (responsible for brown, black, and some shades of green eyes) and lipochrome (responsible for green, blue, and gray eyes). The genetics of eye color inheritance is complex, involving multiple genes with varying degrees of influence. Worried about your teen's group chats? Here's how to reactQuestions every parent must ask in PTM The OCA2 and HERC2 genes, located on chromosome 15, play a significant role in eye color determination. These genes regulate the production and storage of melanin, affecting the amount and distribution of pigments in the iris. Variations in these genes can lead to different eye colors. Blue eyes result from the scattering of light in the iris, rather than the presence of blue pigments. It's the same phenomenon that makes the sky appear blue. The scattering of light occurs when there is little or no melanin in the front part of the iris, allowing light to be scattered rather than absorbed. Motivational quotes for new parents The inheritance of blue eyes follows a recessive pattern. Both parents must carry and pass on the recessive allele for blue eyes to their offspring. If a person inherits one brown-eyed allele and one blue-eyed allele, the brown eye trait is usually dominant, resulting in brown or hazel eyes.

It's important to note that eye color is a polygenic trait influenced by various factors, and predicting the exact eye color of an individual can be challenging. Additionally, environmental factors, such as lighting conditions and the reflection of clothing colors, can create the illusion of different eye colors. In summary, blue eyes are inherited, and the genetic interplay between multiple genes determines eye color. While genetics significantly influence eye color, the precise outcome can vary, contributing to the diversity of eye colors observed in the human population. Raha's striking blue eyes have delighted people around the country and we can only observe if her eyes stay this unique colour or turn darker as she gets older! Only time will tell!

Periods and pregnancy: Why regular cycles are not a guarantee

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Raha Kapoor's blue eyes remind fans of her great-grandfather, Raj Kapoor; here's what genetics says - IndiaTimes