Neuroscience Antibodies & Assays Market Statistics 2020, Technology Analysis Overview, Industry Insights and COVID-19 Pandemic Presenting Future…

Neuroscience Antibodies & Assays Market research report delivers a comprehensive study on production capacity, consumption, import and export for all major regions across the world. Report provides is a professional inclusive study on the current state for the market. Analysis and discussion of important industry like market trends, size, share, growth estimates are mentioned in the report.

Neuroscience involves the study of nervous system, where the research is completely relies on assays and antibodies. These antibodies and assays are specific that helps to identify and examine reactions on the cellular, biochemical and molecular level. Antibody-based approaches are used for the localization, isolation and characterization of targeted proteins that majorly used in the cellular and molecular neuroscience. On the other hand, the use of assays provide an efficient, valuable solution for determination of critical targets that are involved in synaptic signaling, neural development and neurodegeneration.

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Competitive Landscape Neuroscience Antibodies & Assays Market:

The global neuroscience antibodies & assays market is segmented on the basis of product, technology, application and end user. Based on product, the market is segmented as consumables and instruments. On the basis of technology, the global neuroscience antibodies & assays market is segmented into molecular diagnostics, clinical chemistry, immunoassays/immunochemistry and others. Based on application, the market is segmented as in vitro diagnostics, research and drug discovery. Based on end user, the market is segmented as hospitals & diagnostics centers, academic & research institutes and pharmaceutical & biotechnology companies.

The report specifically highlights the Neuroscience Antibodies & Assays market share, company profiles, regional outlook, product portfolio, a record of the recent developments, strategic analysis, key players in the market, sales, distribution chain, manufacturing, production, new market entrants as well as existing market players, advertising, brand value, popular products, demand and supply, and other important factors related to the market to help the new entrants understand the market scenario better.

To comprehend global Neuroscience Antibodies & Assays market dynamics in the world mainly, the worldwide market is analyzed across major global regions: North America (United States, Canada and Mexico), Europe (Germany, France, United Kingdom, Russia and Italy), Asia-Pacific (China, Japan, Korea, India, Southeast Asia and Australia), South America (Brazil, Argentina), Middle East & Africa (Saudi Arabia, UAE, Egypt and South Africa)

Our Sample Report Accommodate a Brief Introduction of the research report, TOC, List of Tables and Figures, Competitive Landscape and Geographic Segmentation, Innovation and Future Developments Based on Research Methodology

Research Objective

To analyze and forecast the market size of global Neuroscience Antibodies & Assays market.

To classify and forecast global Neuroscience Antibodies & Assays market based on product, sources, application.

To identify drivers and challenges for global Neuroscience Antibodies & Assays market.

To examine competitive developments such as mergers & acquisitions, agreements, collaborations and partnerships, etc., in global Neuroscience Antibodies & Assays market.

To conduct pricing analysis for global Neuroscience Antibodies & Assays market.

To identify and analyze the profile of leading players operating in global Neuroscience Antibodies & Assays market.

-To analyze global Neuroscience Antibodies & Assays status, future forecast, growth opportunity, key market and key players.

-To present the Neuroscience Antibodies & Assays development in various regions like United States, Europe and China.

-To strategically profile the key players and comprehensively analyze their development plan and strategies.

-Neuroscience Antibodies & Assays market report helps in making informed business decisions by having complete insights of market and by making in-depth analysis of market segments

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Neuroscience Antibodies & Assays Market Statistics 2020, Technology Analysis Overview, Industry Insights and COVID-19 Pandemic Presenting Future...

The inspiration behind Black In Neuro – UCI News

Sooooo, when are we doing a #BlackInNeuro week?

When Angeline Dukes sent this tweet last July 3, she probably didnt anticipate that the post would soon bring together thousands of Black scholars from all over the globe. Just months after the tweet went viral, the Black In Neuro organizing team put together the inaugural Black In Neuro week and mini conference, drawing undergraduates, graduate students, postdoctoral researchers and faculty members from more than 65 countries to a series of virtual events on neuroscience-related research, professional development, mentorship and racism in neuroscience.

Dukes was inspired to tweet after seeing the successes of other STEM-related coalitions. As a third-year Ph.D. candidate in the Department of Neurobiology & Behavior, she had only one other Black classmate, Elena Dominguez (who has also been instrumental in organizing Black In Neuro). In the overwhelming aftermath of the police killings of George Floyd and Breonna Taylor, the aspiring professor had no Black faculty members she could turn to for support. The movement provided that vital connection.

We wanted to build a community where people felt comfortable talking about race-related issues, sharing research opportunities, and just knowing that there are more of us out there, she says.

The importance of Black mentorsDukes credits Black mentorship for facilitating her growth as an academic. As the child of Trinidadian and Haitian immigrants and a first-generation college graduate, she had to navigate the educational system largely on her own. She attended Fisk University in Nashville, an HBCU, where she majored in biology and graduated summa cum laude.

She originally planned on becoming a pediatrician, but after a few classes at a medical school and some hands-on experience, she realized it wasnt what she was passionate about. Yet she still loved to learn biology and teach it as a lab and teachers assistant.

As a child of immigrants, you grow up thinking you have to become a doctor or a lawyer. I didnt know about other options, she says. Thankfully, I had some incredible Black female professors who told me, If you dont want to go to medical school, you can go to graduate school, and I was like, Oh, what is graduate school? They helped me get into research and navigate the process of applying. They showed me that I can be a professor, too.

Finding her pathThough Dukes now knew she wanted to become an educator and researcher, she was undecided about what her exact research interests were, so she applied to UCIs Interdepartmental Neuroscience Program. There, she would be able to rotate in different labs from various departments, which would expose her to a variety of approaches and help her decide on a specific field.

UCI just so happened to be the first school she interviewed at. I knew the neuroscience research here was amazing. But I also had lots of questions about how supportive the faculty were regarding teaching, mentorship and outreach, because those things are really important to me, she recalls. They addressed all of my concerns and seemed really supportive about it. This was my dream school in a way. I never thought I would actually get accepted.

Dukes was not only accepted into the program, but it was also instantly a perfect fit.

Since she would be moving across the country, Dukes enrolled in the Competitive Edge Summer Research Program, which is designed to support entering doctoral students from diverse backgrounds. It was her first rotation that summer in the addiction neuroscience lab of Christine Fowler, UCI associate professor of neurobiology & behavior that sealed the deal. These days, Dukes dissertation focuses on the long-term effects of nicotine and THC in developing adolescent brains. However, her favorite part of her role as a scholar isnt the research itself. Its being able to lift other people up through her work.

A community of mutual supportI know that the work that Im doing is very interesting, but what I love the most is being able to talk to younger students about it. I love going to the Los Angeles and Compton school districts to tell students about the research that Im doing, she says. I love to show them that this is an option for them, too. If they decide they want to go to college, they can be scientists, professors and anything else they dream of.

Whether its K-12 students or her academic peers, Dukes is constantly striving to reach out and empower others. Last June, Dukes and Dominguez co-led an anti-racism discussion that started theUCI End Racism Initiative, a movement to dismantle systemic racism on campus and beyond.

Black In Neuro is another reflection of her passion for mentorship at every level. Ive connected with a lot of other Black scholars, especially current faculty members. Even though theyve been through graduate school, they didnt have anything like Black In Neuro to offer support when they were going through the process, she says. Im so thankful we can connect with them now, and they can find community, but also that they can serve as mentors to us.

One of the long-term goals for Black In Neuro is a formalized mentoring program for undergraduates and graduate students, and peer mentoring for faculty.

Sources of campus supportThe future of Black In Neuro depends, of course, on external support. Although we are creating this for ourselves, all the work doesnt fall onto us, Dukes says. We need a lot of support from institutions and from departments. If they say they want to increase Black representation at the student and faculty level, they need to support initiatives like this because were putting in the work to not only get Black students interested in neuroscience, but to also keep them in the field.

Thanks to sponsorships from UCI and several other campus institutions, including the School of Biological Sciences, the Department of Neurobiology and Behavior and the UCI Center for Neurobiology of Learning and Memory, Black in Neuro has been able pay all of their speakers for the various panels, talks and events that they have organized.

Theres really no shortage of ways to support the movement, says Michael Yassa, CNLM director and associate dean of diversity, equity and inclusion for the School of Biological Sciences. But my hope is that organizations that do provide support do it for authentic reasons. And along with their contributions, they should make a commitment to institutional culture change to celebrate and promote Black excellence and work to eliminate systemic and institutional barriers that prevent Black scholars from thriving in the academy or industry.

Last year, the UCI Office of Inclusive Excellence instituted the Black Thriving Initiative a campus-wide commitment to eliminate such obstacles at UCI and the community beyond. Led by vice chancellor of diversity, equity and inclusion Douglas Haynes, the initiative among its many priorities is working to ensure that the contributions of Black scholars are always celebrated and that they never have to feel like they dont belong at UCI.

In the School of Biological Sciences, the Office of Diversity, Equity and Inclusion is collaborating with the Office of Inclusive Excellence to address systemic anti-Black racism on campus, improve campus culture, develop federally funded diversity training and faculty hiring initiatives, and support student outreach and recruitment.

Anti-Black systemic racism has for hundreds of years suppressed the voices and contributions of the Black community, says Yassa. Black In Neuro and a number of other similar movements are a huge step to right those wrongs, to fight back against those inequities, and ensure that this generation and the next see hope and freedom from oppression on the horizon.

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The inspiration behind Black In Neuro - UCI News

BioXcel Therapeutics to Present an Update from its Ongoing Trial of BXCL701 in Aggressive Forms of Prostate Cancer at the 2021 ASCO Genitourinary…

NEW HAVEN, Conn., Feb. 04, 2021 (GLOBE NEWSWIRE) -- BioXcel Therapeutics, Inc. ("BioXcel" or the "Company") (Nasdaq: BTAI), a clinical-stage biopharmaceutical company utilizing artificial intelligence approaches to develop transformative medicines in neuroscience and immuno-oncology, today announced that an update from its ongoing Phase 1b/2 trial of BXCL701, the Company's investigational, oral innate immunity activator, in aggressive forms of prostate cancer will be presented in a poster session at the virtual 2021 ASCO Genitourinary ("ASCO GU") Cancers Symposium. ASCO GU is being held from Thursday, February 11, 2021 to Saturday, February 13, 2021.

Poster Presentation Details: Title: BXCL701, first-in-class oral activator of systemic innate immunity pathway, combined with pembrolizumab (Keytruda) in men with metastatic castration-resistant prostate cancer (mCRPC)Poster Session: Prostate Cancer - AdvancedTime: Available starting on February 11, 2021 at 8:00 a.m. Eastern TimeAbstract Number: 124

The abstract will be available on the ASCO GU website at meetinglibrary.asco.org/ on Monday, February 8, 2021 at 5:00 p.m. ET. At the start of the poster session, the poster will be available in the News & Media section of the Companys website at http://www.bioxceltherapeutics.com.

About BXCL701

BXCL701 is an investigational orally administered innate immune activator designed to initiate inflammation in the tumor microenvironment. Approved and experimental immunotherapies often struggle to address cancers that appear "cold" or uninflamed. Therefore, BXCL701 may render "cold" tumors "hot," making them more detectable by the adaptive immune system and thereby facilitating the development of a strong anti-cancer immune response. BTI's preclinical data supports BXCL701's synergy with both current checkpoint inhibitor-based therapies and emerging immunotherapies directed to activate T-cells, such as IL-2.

This candidate is currently being developed as therapy for aggressive forms of prostate cancer ("cold" tumor) and advanced solid tumors that are refractory or treatment nave to checkpoint inhibitors ("hot" tumors).

BioXcel Therapeutics, Inc.

BioXcel Therapeutics, Inc. is a clinical stage biopharmaceutical company focused on drug development that utilizes artificial intelligence approaches to develop transformative medicines in neuroscience and immuno-oncology. BioXcel's drug re-innovation approach leverages existing approved drugs and/or clinically validated product candidates together with big data and proprietary machine learning algorithms to identify new therapeutic indices. BioXcel's two most advanced clinical development programs are BXCL501, an investigational, proprietary, orally dissolving thin film formulation of dexmedetomidine for the treatment of agitation and opioid withdrawal symptoms, and BXCL701, an investigational, orally administered, systemic innate immunity activator in development for the treatment of aggressive forms of prostate cancer and advanced solid tumors that are refractory or treatment nave to checkpoint inhibitors. For more information, please visit http://www.bioxceltherapeutics.com.

Contact Information:

BioXcel Therapeutics, Inc.

http://www.bioxceltherapeutics.com

Investor Relations:

Mary ColemanBioXcel Therapeutics, VP of Investment RelationsMColeman@bioxceltherapeutics.com1.475.238.6837

John GrazianoSolebury Troutjgraziano@soleburytrout.com1.646.378.2942

Media:

Julia DeutschSolebury Troutjdeutsch@soleburytrout.com1.646.378.2967

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BioXcel Therapeutics to Present an Update from its Ongoing Trial of BXCL701 in Aggressive Forms of Prostate Cancer at the 2021 ASCO Genitourinary...

GWPH Stock Price Increases Over 40% Pre-Market: Why It Happened – Pulse 2.0

The stock price of GW Pharmaceuticals PLC (NASDAQ: GWPH) is trading at over 40% pre-market today as of 8:26 AM ET. Investors are responding to an acquisition announcement.

Jazz Pharmaceuticals PLC (NASDAQ: JAZZ) announced it has agreed to buy GW Pharmaceuticals Plc GWPH in a cash-and-stock deal that has a value of $7.2 billion. As part of the deal, Jazz Pharma is going to pay $200 per share in cash and $20 in stock for each share to the company shareholders. This is a premium of about 50% of GW Pharmaceuticals closing price on Tuesday and 60% over the 30-day volume-weighted average price.

GW is a leader in discovering, developing, manufacturing, and commercializing novel, regulatory approved therapeutics from its proprietary cannabinoid product platform to address a broad range of diseases. And the companys lead product Epidiolex (cannabidiol) oral solution is approved in patients one-year and older for the treatment of seizures associated with Lennox-Gastaut Syndrome (LGS), Dravet Syndrome, and Tuberous Sclerosis Complex (TSC) all of which are rare diseases characterized by severe early-onset epilepsy.

Epidiolex was the first plant-derived cannabinoid medicine ever approved by the U.S. Food and Drug Administration (FDA). And this product has also been approved, under the tradename Epidyolex by the European Medicines Agency (EMA) in patients two years of age and older for the adjunctive treatment of seizures associated with LGS and Dravet syndrome in conjunction with clobazam and is under EMA review for the treatment of seizures associated with TSC. Plus there are considerable opportunities to pursue other indications within the epilepsy field, including other treatment-resistant epilepsies where significant unmet needs of patients exist.

The deal is expected to close in the Q2. And it is expected to boost profit in the first year after close along with driving double-digit revenue growth.

KEY QUOTES:

Jazz is proud of our leadership position in sleep medicines and rapidly growing oncology business. We are excited to add GWs industry-leading cannabinoid platform, innovative pipeline and products, which will strengthen and broaden our neuroscience portfolio, further diversify our revenue and drive sustainable, long-term value creation opportunities. We are joining two teams that share a passion for, and track record of, developing differentiated therapies that advance science and transform the lives of patients. This will help facilitate a successful integration and bring added capabilities to Jazz. Given the strength of our balance sheet and the meaningful financial drivers of the transaction, we are confident in the value we can deliver to both companies shareholders and patients. We look forward to welcoming the GW team to Jazz to build an even stronger company.

Bruce Cozadd, chairman and CEO of Jazz Pharmaceuticals

Over the last two decades, GW has built an unparalleled global leadership position in cannabinoid science, including the successful launch of Epidiolex, a breakthrough product within the field of epilepsy, and a diverse and robust neuroscience pipeline. We believe that Jazz is an ideal growth partner that is committed to supporting our commercial efforts, as well as ongoing clinical and research programs. We have a shared vision of developing and commercializing innovative medicines that address significant unmet needs in neuroscience and an approach of putting patients first. Together, we will have an opportunity to reach and impact more patients through a broader portfolio of neuroscience-focused therapies than ever before.

Justin Gover, CEO of GW Pharmaceuticals

Disclaimer: This content is intended for informational purposes. Before making any investment, you should do your own analysis.

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GWPH Stock Price Increases Over 40% Pre-Market: Why It Happened - Pulse 2.0

Study suggests that hormone seasonality in humans may have a physiological peak season for biological functions – EdexLive

A recent study has provided researchers with a dataset of millions of hormone tests from medical records that shows seasonality with a winter-spring peak in hormones for reproduction, growth, metabolism, and stress adaptation. The hormone seasonality indicates that, like other animals, humans may have a physiological peak season for basic biological functions.

Uri Alon and colleagues analysed the results of hormone blood tests between 2002 and 2017 from nearly 3.5 million adults aged 20 to 80 years and living in Israel. Data were sourced from the medical database of the Israeli health-service Clalit. The test results revealed that human hormones exhibit patterns of seasonality. Effector hormones peaked between winter and spring. However, most upstream-regulating pituitary hormones for growth, reproduction, and stress peaked in late summer.

The delay of pituitary hormones was unexpected, given that hormone circuit delays typically last hours rather than months. The authors also determined that adrenal and pituitary gland masses grow within months due to hormones' trophic effects, which produce a feedback circuit with a natural annual frequency. The findings suggest that hormone seasonality in humans may have a physiological peak season for biological functions, according to the authors.

The specific seasonal phases of the hormones were used to suggest a model for a circannual clock in humans and animals that can keep track of the seasons, similar in spirit to the circadian clock that keeps track of the time of day.

Hormones control the major biological functions of the stress response, growth, metabolism, and reproduction. In animals, these hormones show pronounced seasonality, with different set-points for different seasons. In humans, the seasonality of these hormones remains unclear, due to a lack of datasets large enough to discern common patterns and cover all hormones. The study analyzes an Israeli health record on 46 million person-years, including millions of hormone blood tests.

Clear seasonal patterns were found, the effector hormones peak in winter-spring, whereas most of their upstream regulating pituitary hormones peak only months later, in summer. This delay of months is unexpected because known delays in the hormone circuits last for hours.

This study explains the precise delays and amplitudes by proposing and testing a mechanism for the circannual clock: The gland masses grow with a timescale of months due to trophic effects of the hormones, generating a feedback circuit with a natural frequency of about a year that can entrain to the seasons. Thus, humans may show coordinated seasonal set-points with a winter-spring peak in the growth, stress, metabolism, and reproduction axes.

Major biological functions in mammals, like growth, reproduction, metabolism, and stress adaptation are controlled by dedicated hormonal axes. In each axis, signals from the hypothalamus cause secretion of specific pituitary hormones into the bloodstream. The pituitary hormones instruct a peripheral organ to secrete effector hormones with widespread effects on many tissues.

For example, the stress response is governed by the hypothalamic-pituitary-adrenal (HPA) axis: Physiological and psychological stress signals cause the hypothalamus to induce secretion of ACTH from the pituitary, which instructs the adrenal cortex to secrete cortisol. These axes act to maintain physiological set points. The setpoints can change to adapt to different situations, a concept known as rheostasis.

Animals show seasonal changes in the pituitary and effector hormones that govern seasonality in reproduction, activity, growth, pigmentation, morphology, and migration. This adaptive physiology includes changes in body composition, organ size, and function. In general, hormone seasonality is thought to be a dominant regulator of physiological and behavioural traits in animals.

Animals show these changes with a circannual rhythm even when maintained in constant photoperiod and temperature conditions. They cycle without external signals, by means of an internal oscillator with a period of about, but not exactly, 1 y. The mechanism and physiological location of this circannual clock is a subject of current research. A key component is the pars tuberalis in the pituitary stalk, whose thyrotrophin cells oscillate between high and low states of hormone production. This area receives input on photoperiod from melatonin signals.

Whether hormones show seasonality in humans has not been studied comprehensively by tracking many hormones in a large number of participants. Each axis has been studied separately, usually with small samples. These studies suggest that thyroid hormones and cortisol show a seasonal variation on the order of 10%. The studies are limited by considerations of circadian rhythms which affect cortisol and other hormones.

To study human hormone seasonality requires a large dataset with comprehensive coverage of all hormones. Such a study was provided using an Israeli medical record database with millions of blood tests. It addresses the circadian rhythm concern using the time of each test and found coordinated seasonality with a winter/spring peak in effector hormones and surprising antiphase between pituitary and effector hormones.

It provides an explanation for this antiphase by showing that trophic effects of the hormones create a circuit in which the functional masses of the glands changes over the year and can entrain to yearly signals. The results support a winter-spring peak for human reproduction, metabolism, growth, and stress adaptation.

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Study suggests that hormone seasonality in humans may have a physiological peak season for biological functions - EdexLive

Study Finds MediPines’ Breakthrough Non-invasive Gas Exchange Method Highly Precise: Ideal for Covid Response – PRNewswire

Using the MediPines AGM100, a respiratory medical device,researchers were able to demonstrate that the new breath-based measurement of gas exchange efficiency has very low variability and is highly correlated with established blood-sampling methods.

In the new non-invasive method of measuring gas exchange efficiency, concerns of variability in expired breath samples have been addressed.The variability of gas concentrations throughout the respiratory cycle can range dramatically; however, when steady state end-tidal gas samples are used, gas concentration is remarkably constant.Thecurrent study found the very lowvariability of end tidalgasmeasurementswithin subjectsof1.3%or 1.4 mmHg for oxygen and 1.8% or 0.7 mmHg for carbon dioxide.The traditional method (Riley Method) does not directly measure the lung alveolar gas level but estimates the alveolar level from a calculation that uses arterial blood gas values and a number of assumptions.

In the age of respiratory diseases like Covid-19, where stability and repeatability of patient measurements matter, this study's conclusion is a breakthrough finding for quicker, non-invasive methods that are ideally suited for the hospital. A breath-based gas exchange analysis using the AGM100 is easy to obtain for both practitioner and patient. The gas exchange analysis provided by the AGM100 requires the patient to simply breath into a mouthpiece and can be completed within two minutes.

"This study demonstrates the merits of a breath-sampling based approach, given the low variability, which allows for high reproducibility and reliability in clinical practice. This is consistent with our previous study that demonstrated a very high correlation and low measurement bias of directly measured arterial PO2, with that estimated non-invasively from the AGM100 in a range of different physiological states," said Dr. Phil Ainslie,Canada Research Chair and Co-Director of the Centre for Heart lung and Vascular Health, School of Health and Exercise Sciences at theUniversity of British Columbia.

This finding further supports a clinical validation study published in 2020 by researchers from the University of British Columbia and Duke University Medical Center, demonstrating the high precision of the new expired breath sampling method.

MediPines AGM100

MediPines AGM100is the world's first non-invasive gas exchange analyzer. This advanced respiratory monitoring system was designed to rapidly detect respiratory impairment caused by conditions such as COVID-19, chronic obstructive pulmonary disease (COPD), pneumonia, ARDS, pulmonary edema, and pulmonary embolism. The device is FDA cleared and approved for Health Canada COVID-19 Emergency Use. It provides a comprehensive panel of respiratory measurements including blood oxygen levels, Oxygen Deficit (A-a gradient), P/F ratio, and alveolar oxygen and carbon dioxide levels.

About MediPines

MediPines Corporation, based inCalifornia, is a market leader in respiratory assessment and monitoring of pulmonary gas exchange. The company mission is to advance respiratory medicine by providing physiology-based respiratory devices that enhance clinical effectiveness and achieve better patient outcomes.

MediPines.com

Media contact: Carissa Drews 949-398-4670 [emailprotected]

SOURCE MediPines

http://medipines.com

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Study Finds MediPines' Breakthrough Non-invasive Gas Exchange Method Highly Precise: Ideal for Covid Response - PRNewswire

Wellbeing webinar: improved brain function via meditation – Epigram

By Emma Hanson, English Literature MA

The Croft Magazine // In the final webinar of Transcendental Meditation Societys 360 Degree Wellbeing series, Emma learned about the benefits of transcendental meditation from Gaetano Arena and James Miles.

Gaetano Arena is a PhD student at the University of Bristol who set up the 360 Wellbeing series. I asked him about the impact that it has had on his life:

I learnt transcendental meditation (TM) a couple of years ago when, at the end of my PhD in Aerospace Engineering, I was really struggling with my own mental health. It was very hard to concentrate and write my dissertation, and my mood and energy levels were always incredibly low. I thought that it was only stress and some personal issues that were causing this sudden drop in my motivation and enjoyment of life.

I felt some of the benefits of TM just days after I had tried my first meditation. I was feeling more and more energetic and happy each day, but the main benefit I noticed was that I became much more aware of my physiology and its connection to my mind. I could notice almost immediately the effect food and sleep had on my mood and energy level.

Likewise, I could feel how introducing yoga and a more regular workout routine had a massive impact on my mental health. Basically, the meditation practice removed deep layers of stress that prevented me from realising what was causing the issues with my own physiology and mental health.

TM is a very simple technique, best done twice a day for 20 minutes in the morning and evening. It is a meditation technique that uses a mantra to go beyond the thinking process and reach a fourth state of consciousness to transcend thoughts and in this way reach a state of peace and rest.

Maharishi Mahesh Yogi introduced this technique to the Western world in the 1950s and it has since been practised by celebrities such as Jerry Seinfeld and Hugh Jackman. Celebrities are fans of it, but what makes transcendental meditation is its simplicity.

So how do you actually do it? As I said before, TM is a type of mantra meditation. You simply close your eyes and chant a mantra. Mantras can be found by searching transcendental meditation mantras on YouTube, and you can find one that works for you. There is also a free app called 1 Giant Mind, which offers a guided introduction to TM meditation, and the option to do a 30-day challenge.

TM allows you to reset yourself. It makes us more efficient, stops us procrastinating (the dream!), and gives us the ability to focus more sharply by developing our full mental potential.

Patrice Gladwin, a transcendental meditation teacher, attested to the benefits of TM, commenting: I love teaching TM as it makes life so much more joyful and stronger than life without it.

Gaetano talked about why he felt the need to set up this wellbeing series and educate students about various aspects of wellbeing:

I was shocked when I read the studies and annual reports on the wellbeing and mental health of UoB students. Therefore, I submitted a proposal to the UoB Alumni Grant Award, asking to sponsor the university's TM Society for the organisation of wellbeing courses that I could exploit to spread the awareness of TM and several healthy habits among university students. The grant was eventually assigned, and, with the help of the TM national organisation, I have organised the 360 Wellbeing Webinar. I am really grateful to the UoB Alumni Group for the support.

At the start of the first session, James Miles talked about the importance of our wellbeing, summarising the importance of the techniques learnt over the course of this webinar series.

We all want more energy, we want to be creative, we want full use of our brain functioning, we want to be successful, happy, and reduce stress. Most of all we want to enjoy life. And we must remember that we can achieve this because our wellbeing is in our own hands.

Even if you missed the 360 Wellbeing webinar series, you can easily access information about the techniques discussed by reading my other articles on sleep hygiene, the benefits of yoga and how Ayurveda can support wellbeing. As James Miles concisely says, your wellbeing is in your own hands, and the benefits of these four practices have the potential to transform your university experience.

Featured image: Epigram / Robin Ireland

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Wellbeing webinar: improved brain function via meditation - Epigram

Key to true health: A healthy mind and a healthy body always go hand in hand – YourStory

When it comes to feeling great health, it should include energy, mental equilibrium, great sleep, greater resilience to stress, and amazing creativity. Whenever you struggle with challenges involving your mind and stress, it will impact your physiology.

When you struggle with physical symptoms and conditions, it will impact your mental health. This is why the key to true health is to bring some focus into supporting a healthy body and working towards a healthy mind.

One thing that cannot be changed is stressors all around. Stress can be electromagnetic, which is something that is a part of the information age. Stress can be physiological from nutritional deficiencies or chronic inflammation. Stress can be caused by poor sleep.

The stressors might vary for each one of us, but we do not live in a bubble, and therefore we can only work on our resilience. Resilience is something that can be changed dramatically in spite of the level of stress. It might not seem possible, but it is true.

Those who sleep poorly, have nutritional deficiencies, and poor blood sugar balance struggle with resilience. Time is a big factor when it comes to a healthy mind. Some tweaks or hacks can support a healthy mind, one that is balanced and calm. What are some of the hacks that can help you keep a stable and healthy mind?

Even amid the number of apps and planners out there, there is something unique about a handwritten to-do list. I will admit that I also use a planner, but it does not come anywhere close to my quickly scribbled lists.

Image source: Shutterstock

There is a wonderful practice of scribbling your list in five minutes and putting down whatever comes in your mind the moment you wake up. This allows you to maintain clarity and great awareness through the day since this activity helps you dump everything on your mind at the get-go.

It is time-saving, releases clutter within your mind very early in the morning, and taps into your subconscious mind when you are just moving from sleep to wake.

You might wonder how taking 30 minutes to dance in your room is time-saving. This goes back to ancient wisdom. One of the reasons that your mind feels unhealthy and cluttered is restless energy.

The energy within your body is exactly like the wind. You cannot see your energy. But you can see the impact of that energy as to how cluttered, restless or unhealthy your mind feels.

In fact, taking 30 minutes in the morning to dance in your room without anyone around, where you can express your moves freely, burns away the restless energy within yourself.

What happens through the day is much better productivity and focus that saves time in everything else that you do. It is important to do this without anyone else in the room so that you can really let go!

Image source: Shutterstock

I found that the one year when I did not make separate lists, my entire year, including every month and every day, was filled with uncertainty, chaos, and lack of vision for greater goals. Separate lists should be written out for main things to do the whole year, what to do for each month as well as breakdown for each category, which will be unique to you.

You cannot imagine how much time this saves through the year in terms of direction and planning. Someone asked me how did I manage so much through the day? It had to do with this very simple time-saving practice.

I also encourage you to get a colourful book to do all of this, which will support your creativity and inspiration.

Not only is it highly possible to fall into the trap of not spending time with a loved one as you get overwhelmed by the list of things to do, but it is also very easy to not realise the value of this very simple five-minute practice. One of the biggest reasons for an unhealthy mind and poor resilience to stress is cortisol.

Cortisol is your stress hormone, which is the physiological reason that you feel more stressed. Oxytocin is a peptide hormone and neuropeptide, which is produced in your hypothalamus and then released by your pituitary. It plays a key role in breastfeeding, sexual reproduction, the birth of a child, a postnatal period, and in overall social bonding.

The fascinating thing about oxytocin is that is shares an antagonistic relationship with cortisol. When you spend five minutes hugging someone you love, your body releases oxytocin and reduces cortisol! This means that you instantly increase your resilience and have a calmer mind.

One of the main reasons for an unhealthy mind is the inability to set boundaries. Imagine a child who looks forward to the surprise at the end of a tiring school day. If I tell my little boy that I have something wonderful planned for his dinner, there is a world of difference in how inspired he is all day. He does not go around wasting his time, he is productive, and he is much more stable in his mood.

We truly are not all that different from the children in our lives. Just this morning, I had a conversation with a client who was unable to feel calm, productive or healthy because he was always waiting for the phone to ring even if it was at midnight.

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This one little hack was magic to my productivity, and even with much more on my plate now, I have never been as productive or as relaxed.

Saving time is not something that should be viewed with a reductionist approach of just saving time on one specific day. Time-saving has to be viewed from a greater perspective, where little hacks introduced and made a big part of your life. It should shift you towards a space where you have a calmer mind that supports your body.

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Key to true health: A healthy mind and a healthy body always go hand in hand - YourStory

Strides in spatial genomics & transcriptomics market to transform landscape of liver physiology and disease biology – TMR Research Blog

Spatial genomics and transcriptomics have emerged as valuable tools in understanding liver physiology and disease biology. The drive for discovering new therapeutic targets for chronic liver diseases and cancer is a key trend shaping the evolving contours of the spatial genomics and transcriptomics market. The tools show incredible promise in studying rare cells such as liver progenitor cells and non-parenchymal cells in cancer. Strides made in computational analyses have led better characterisation of primary liver cancers. Expanding horizon of immunotherapy and strides made in precision medicine have broadened the canvas for industry stakeholders in the spatial genomics and transcriptomics market. Growing popularity of single-cell RNA sequencing is a key trend bolstering the prospects.

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The focus of creation of high-quality sequencing libraries or cell atlases has stirred the attention of researchers to harness spatial genomics and novel sequencing-based technologies such as spatial transcriptomics. Growing prevalence of chronic diseases and cancers has spurred the number of gene expression studies in tissues, thereby bolstering the expansion of the avenue in the spatial genomics and transcriptomics market.

Need for novel treatment strategies for liver cancer drives prospects

The need for high-quality genomic study for genetic engineering is a key factor propelling the application of next-generation sequencing. A case in point visualizing the RNA molecules at resolution equal or less than 100m. Over the years, researchers have been leveraging spatial genomics and transcriptomics for studying heterogeneity within liver cancer and expanding the understanding of the underlying tumour microenvironment. Spatial transcriptomics is likely to pave way to novel treatment strategies for liver cancer. In recent years, new spatial transcriptomic approaches have helped researchers unravel the treatment avenue for genetic diseases.

Strides made in biomedical research in oncology using high-throughput sequencing has expanded opportunities for industries looking to expand the stakes in the market. Some of the key players are Bio-Techne, Fluidigm Corporation, Illumina, and NanoString Technologies.

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Strides in spatial genomics & transcriptomics market to transform landscape of liver physiology and disease biology - TMR Research Blog

The hidden burdens of healthcare workers – University of Victoria – University of Victoria News

Tasha Vollo-Crawford has long known that her nursing job causes her stressall the more so since the start of the pandemic.

But it wasnt until a University of Victoria researcher put a watch-sized heart rate monitor on her wrist, to wear during her shifts, that she fully grasped the impact of that stress on her physical health.

I knew that my heart rate was always high on my shift, from beginning to end, says Vollo-Crawford, a nurse at Victoria General Hospital. I see now that Im in a constant state of stress at work.

Vollo-Crawford is one of the Victoria-area health care workers recruited by UVic grad student Marisa Harrington for a study monitoring physiological stress responses in Victoria-area health care workers.

These are still early days of data collection. But for Harrington, whos pursuing a masters degree in exercise physiology, the results are already confirming what every health-care worker already knows: their work is stressful.

This is such a unique area to research during a pandemic, says Harrington, whose study is funded by WorkSafe BC and UVics Centre for Occupational Research and Testing, in the School of Exercise Science, Physical and Health Education. Her research is evaluating how well those who carry the responsibility to keep us safe and healthy, are staying safe and healthy themselves, she says.

The study is part of broader research being conducted by Lynneth Stuart-Hill, an occupational physiologist and associate professor at UVic. She is studying the stress responses of Greater Victoria front-line healthcare workers whose jobs include shift work.

The main focus of Harringtons research initially revolved around shift work itself. But then COVID-19 struck, bringing the rare opportunity to examine the objective and subjective stress levels of nursesnot just in terms of shift work, but during a global health crisis.

The 10 nurses who participated in Harringtons ongoing study wore monitoring equipment over an eight-day shift rotation. Their sleep patterns were monitored alongside the rate and variability of their heartbeats.

A reduction in variability is a signal that the bodys sympathetic nervous systemresponsible for our fight, flight or freeze responseis chronically dominating the parasympathetic nervous system, which keeps us calm. Its one of the indices of stress. When its out of kilter, we know that this is a body out of sync, says Stuart-Hill.

The research project also analyzes nurses saliva for three markers associated with stress: cortisol, melatonin, and interleukin-y. The last of these is a cytokinea protein related to the bodys immune response, now getting attention for the deadly cytokine storms that affect some people with COVID-19.

Participants also kept logs while at work, noting any high-stress incidents over the shift that might later be correlated with a change in their physiological responses.

Were still analyzing, but we have seen significant data already, around sleep in particular, says Harrington. These nurses are spending more time in light sleep and less in REM sleep. Weve looked at the cardiovascular data and there is definitely an effect there as well.

We know that this is a population that feels stressed psychologically. Now, were establishing that theres a measureable physiological impact as well.

Harringtons research will help fill critical knowledge gaps, says Stuart-Hill. Much of the research done to date on the physiological impact of stressful work has involved male-dominated professions such as firefighting and logging. Stuart-Hill hopes to build on Harringtons research findings through future studies of long-term care employees, paramedics and other community-based health care workers.

The nurses are delighted that were studying this, adds Stuart-Hill. What were learning through the data are the things they inherently know.

Ongoing analysis will examine differences in data depending on a participants specific job role. But Harrington says early results are establishing that participants stress responses are significant and similar, regardless of what department or hospital they work in.

The stress of the pandemic for health care workers goes far beyond whether theyre actually working on a COVID ward, says Stuart-Hill.

These workers have to presume that anyone they are dealing with could have COVID, she says. If you work in these facilities, you also have to worry about bringing COVID to work, so your own home life is more stressed.

Can you still hug and cuddle your kids, given that theyre back in school? Can you share a bed with your partner? You have to worry about all of that.

Phase two of Harringtons study is now underway with a new round of study subjects. She anticipates concluding her work this spring.

Stuart-Hill and Harrington ultimately hope the research will shed light on better ways to manage the stress of health-care work. The shift rotation that Island Health uses for hospital-based nurses (two day shifts, two night shifts, and four days off) is notorious for disrupting normal sleep patterns, notes Stuart-Hill. Add in a pandemic and its uncharted territory.

The anguish that health care workers are seeing in their patients, the frustration of seeing people in their communities not taking this seriously, the lack of camaraderieits amazing theyre able to keep doing what they do, says Stuart-Hill.

I think theres going to be long-term fallout from this period. This data will provide some evidence for that when the time comes.

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The hidden burdens of healthcare workers - University of Victoria - University of Victoria News