Canine genetics, health to be explored at summit – VeterinaryPracticeNews.com

Preserving and enhancing genetic diversity in dog breeds is set to be explored at an upcoming virtual educational conference.

Scheduled for Feb. 15 and 16, Embark Veterinarys Canine Health Summit will feature presentations, panel discussions, and interactive sessions presented by various experts across the canine health landscape.

The free event, which targets veterinarians, breeders, and pet owners, will also include a keynote address by Duke University professor, Brian Hare, PhD, MA. Additionally, a roundtable discussion led by the Westminster Kennel Club will explore the history of purebred dogs, and how breeders and owners can work together to improve the long term health and vitality of specific breeds.

This summit is an opportunity to bring together a diverse group of stakeholders who are all committed to canine health and discuss ways to work together to accelerate the pace of discovery in the future, says Embarks chief science officer, Adam Boyko, PhD.

In lieu of registration fees, attendees are invited to contribute to the summits fundraiser, benefiting Morris Animal Foundation to support canine health research. Embark will also provide a matching donation of up to $5,000, the company says.

Morris Animal Foundation, as part of its research portfolio, has a long history of investing in canine genetics research to advance the health of dogs, says the foundations chief development officer, Ryan Welch. Were deeply appreciative of the generosity of Embark, and participants in the Canine Health Summit, for their contributions to help ensure this work continues.

To register, click here.

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Canine genetics, health to be explored at summit - VeterinaryPracticeNews.com

SOPHiA GENETICS and the Spanish Lung Cancer Group Team Up to Explore the Predictive Potential of Multimodal Health Data in Resectable Stage IIIA…

The collaboration with the Spanish Lung Cancer Group (Grupo Espaol de Cncer de Pulmn GECP), a Spanish cooperative group for the research on lung cancer, is to show the potential of SOPHiA Radiomics a groundbreaking application that analyzes medical images for research use put to use in an additional retrospective analysis of the data from the phase 2 NADIM clinical trial (NCT03081689) (the NADIM trial).

The NADIM trial, funded by Bristol-Myers Squibb and part of the European Union's Horizon 2020 research and innovation program, aimed to assess the antitumor activity and safety of neoadjuvant chemoimmunotherapy for resectable stage IIIA NSCLC. The important results recently published in TheLancet Oncology supported the addition of neoadjuvant nivolumab to platinum-based chemotherapy in patients with resectable stage IIIA NSCLC. This very aggressive type of cancer is unfortunately terminal in most patients with locally advanced staged disease; these results could therefore support a change of perception of locally advanced lung cancer as a potentially lethal disease to one that is curable.

Additional data are expected to be generated through the analysis of the radiology images of NADIM patients through the SOPHiA Radiomics Platform. These data will then be combined with clinical, biological, and genomics data, and multimodal machine learning models will be developed to predict response to neoadjuvant treatment, using baseline and pre-surgery data. The predictive analysis will also aim to stratify patient cohorts with regard to progression-free and overall survival.

"We are very happy to collaborate in this innovative and revolutionary project that opens the door to a new precision medicine. Certainly, this partnership will improve the knowledge relating to the treatment for this group of patients and will allow to approach the best prospects for curing early-stage non-small cell lung cancer (NSCLC)," said Dr. Mariano Provencio, Head of the Medical Oncology Department at Puerta de Hierro University Hospital in Madrid and lead investigator of the NADIM trial.

"We are very excited to apply our radiomics and multimodal analytics capabilities to such an important clinical question," said Prof. Thierry Colin, Vice-President of Radiomics Research at SOPHiA GENETICS. "In the Spanish Lung Cancer Group, we have found visionary partners that clearly see the promise of next-generation health data such as radiomics being married with tech-enabled solutions in artificial intelligence to generate entirely novel clinical insights for the benefit of oncology patients."

"Unlocking the synergistic potential of multimodal health data through artificial intelligence holds revolutionary promise for the future of personalized medicine in oncology and many other health conditions. We are inspired by the potential to positively impact on patients by supporting their care providers in predicting the best course of treatment," said Dr. Philippe Menu, Chief Medical Officer at SOPHiA GENETICS.

The NADIM trial involved 18 centers from the Spanish Lung Cancer Network that will contribute their data to the joint project.

Results from the additional analysis of NADIM trial data are expected to be available later this year.

About SOPHiA GENETICS

SOPHiA GENETICS is a health tech company democratizing Data-Driven Medicine to improve health outcomes and economics worldwide. By unlocking the power of new-generation health data for cancer and rare diseases management, the universal SOPHiA Platform allows clinical researchers to act with precision and confidence. The company's innovative approach enables an ever-expanding community of over 1,000 institutions to benefit from knowledge sharing, fostering a new era in healthcare. SOPHiA's achievement is recognized by the MIT Technology Review's "50 Smartest Companies".

More info: SOPHiAGENETICS.COM, follow @SOPHiAGENETICS on Twitter.

About the Spanish Lung Cancer Group

The SLCG is an independent, non-profit, cooperative group founded in 1991 to promote the study and research of lung cancer. The group is composed of 525 medical professionalsoncologists, thoracic surgery specialists, radiotherapists and basic researchersand unites 177 public and private centers across Spain.The group has treated over 37,000 patients in different studies and clinical trials, the results of which have been presented and published at national and international congresses and in leading medical journals.

More info: gecp.com, follow @gecp_org on Twitter.

SOPHIA GENETICS Media ContactSophie ReymondPR & Communications Manager [emailprotected]+41 79 863 11 10

SLCG ContactRita Perales [emailprotected] +34 670 24 70 50

SOURCE SOPHiA GENETICS

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Our genetics shape the micro-organisms that live within us – Epigram

By Lucy Mahony, Fourth Year, Bioinformatics

Researchers from the University of Bristol have contributed to a study showing that our DNA influences which types of microbes live inside our gut. The study is a key piece in the puzzle of understanding our gut microbiomes and how they might play a significant role in influencing our health.

Humans are walking petri dishes, with millions of microbes covering both the inside and outside of our bodies. We have roughly the same number of micro-organisms living inside our gut as human cells in our entire body. These specific micro-organisms are referred to as our microbiome.

The microbiome is of considerable interest to scientists, due to its well-known effects on our immune health, mental well-being, drug metabolism and even risk of cancer. However, how exactly the microbiome does this and why people have different compositions of micro-organisms inside their gut is not fully understood.

This collaborative study, published in Nature Genetics, involved over twenty research groups from across the globe and sampling from over 18,000 participants. The report found that at least two genes have an impact in determining which microbes we have in our gut. Firstly, the lactase gene was identified. This gene influences the abundance of a bacterial species called Bifidobacteria, which helps us digest lactose. The second gene is called the fucosyl transferase gene. This gene determines the abundance of a species of bacteria called Ruminococcus torques.

Dr Wade, a lecturer at the University of Bristol, who was one of the researchers on this study commented: What surprised me was how complex these genetic signals were. It was already expected that our genetic make-up would have some kind of impact on our microbiome. However, rather than a simple relationship, this study showed that many of the genes impacting the microbiome also influence human traits, which then in turn further influence the microbes.

The study also used a technique called Mendelian Randomization when analysing their results. This technique has been pioneered in Bristol and allowed the researchers to look at the relationship between the microbiome and human disease occurrence. They found that people whose microbiome had a higher abundance of a group of bacteria called Actinobacteria and its subgroup Bifidobacterium, might be protected from developing ulcers. They also found that the presence of certain members of the bacterial family Oxalobacteraceae might protect people from rheumatoid arthritis.

To better understand the links between human genetics and the gut microbiome, Dr Wade explains that inter-disciplinary collaboration between genetic epidemiologists and microbiologists will be required. [] We are working hard to apply complex methods with inter-disciplinary collaboration to understand the causal role played by the gut microbiome and human health.

There is a plethora of future work required before we can fully understand these interactions and translate them into healthcare.

Featured Image: National Human Genome Research Institute / Microbiome

Do you think about ways to take care of your microbiome? If yes, what are they?

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Our genetics shape the micro-organisms that live within us - Epigram

Science reveals genetic reasons behind different face shapes – Open Access Government

The human face has endless ways of existing, this immense variation witnessed for centuries across ethnicities and continents, across gender and language barriers.

Despite this multitude of ways to have a face, the global cosmetic surgery industry is expected to hit $50.5 billion by 2027.

It is currently the age of The Instagram Face leading individuals to pursue a specific set of features, which celebrity makeup artist Colby Smith described as: an overly tan skin tone, a South Asian influence with the brows and eye shape, an African-American influence with the lips, a Caucasian influence with the nose, a cheek structure that is predominantly Native American and Middle Eastern.

Despite how multicultural this ideal face appears, it is dismissive of genetic difference. The faces that are extensively crafted to look like this, via surgery or filter, have a racial ambiguity that disowns any real affiliation to race. This in itself is a worrying sentiment, as darker skinned people across the world remain at risk of discrimination.

Researchers in this study wanted to understand the legacy of the faces we have today where did they come from? And what could those genes tell them about ancestral adaptions of the face?

Recently, UCL researchers found 32 gene regions that influenced features such as nose, lip, jaw, and brow shape. Nine of these regions were completely new discoveries, while the others validated genes with little prior evidence.

The team analysed data from more than 6,000 volunteers across Latin America. This study compared genetic information from the study participants with characteristics of their face shape, quantified with 59 measurements (distances, angles and ratios between set points) from photos of the participants faces in profile.

The international research team, led from UCL, Aix-Marseille University and The Open University, found that one of the genes appears to have been inherited from the Denisovans. They are an extinct group of ancient humans, who lived tens of thousands of years ago.

The team found that the gene, TBX15, which contributes to lip shape, was linked with genetic data found in the Denisovan people, providing a clue to the genes origin.

One of the newly discovered genes found in this study is VPS13B, which influenced nose pointiness the researchers also found that this gene affects nose structure in mice. This further suggests there is a link between mammal gene influences.

Co-corresponding author Dr Kaustubh Adhikari (UCL Genetics, Evolution & Environment and The Open University) commented: The face shape genes we found may have been the product of evolution as ancient humans evolved to adapt to their environments. Possibly, the version of the gene determining lip shape that was present in the Denisovans could have helped in body fat distribution to make them better suited to the cold climates of Central Asia, and was passed on to modern humans when the two groups met and interbred.

The Denisovans lived in central Asia, and other studies suggest they interbred with modern humans, as some of their DNA lives on in Pacific Islanders and Indigenous people of the Americas.

Co-first author Dr Pierre Faux (Aix-Marseille University) said: To our knowledge this is the first time that a version of a gene inherited from ancient humans is associated with a facial feature in modern humans.

In this case, it was only possible because we moved beyond Eurocentric research; modern-day Europeans do not carry any DNA from the Denisovans, but Native Americans do.

Co-corresponding author Dr Kaustubh Adhikari (UCL Genetics, Evolution & Environment and The Open University) said: The face shape genes we found may have been the product of evolution as ancient humans evolved to adapt to their environments. Possibly, the version of the gene determining lip shape that was present in the Denisovans could have helped in body fat distribution to make them better suited to the cold climates of Central Asia, and was passed on to modern humans when the two groups met and interbred.

Read the full study here.

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To Fight COVID-19 Misinformation, WHO Is Partnering With Big Tech : Goats and Soda – NPR

Open up any social media app on your phone and you'll see it: links to COVID-19 information from trustworthy sources. Here, a Twitter screen reads, "No, 5G isn't causing coronavirus." Michele Abercrombie/NPR hide caption

Open up any social media app on your phone and you'll see it: links to COVID-19 information from trustworthy sources. Here, a Twitter screen reads, "No, 5G isn't causing coronavirus."

Open up any social media app on your phone and you'll likely see links to COVID-19 information from trustworthy sources.

Pinned to the top of Instagram's search function, the handles of the U.S. Centers for Disease Control and Prevention and the World Health Organization are prominently featured. Click and you'll find posts and stories how to keep safe during the pandemic.

In the home section of the YouTube app, there's a playlist of videos that promote vaccination and counteract vaccination misinformation from WHO, the Journal of the American Medical Association and GAVI, the Vaccine Alliance.

And on the Twitter app, you might spot a warning under posts with fake or misleading COVID-19 information. A tweet from a user falsely proclaiming that 5G causes coronavirus, for example, has a big blue exclamation mark with a message from Twitter: "Get the facts about COVID-19." It links to a story debunking the claim from a U.K. media outlet called iNews.

About Goats and Soda

Goats and Soda is NPR's global health and development blog. We tell stories of life in our changing world, focusing on low- and middle-income countries. And we keep in mind that we're all neighbors in this global village. Sign up for our weekly newsletter. Learn more about our team and coverage.

In the noisy news landscape, these are just some of the features launched by the tech industry to bring down COVID-19 misinformation and deliver facts to the public.

This effort didn't happen spontaneously. The World Health Organization sparked the efforts in Feb. 2020 in the early days of the coronavirus crisis. The U.N. agency teamed up with over 40 tech companies to help disseminate facts, minimize the spread of false information and remove misleading posts.

But there's one big question that's tough to answer: Is it working?

Have any of these efforts actually changed people's behavior in the pandemic or encouraged them to turn to more credible sources?

Health messaging experts and misinformation specialists interviewed for this story praise WHO's efforts to reach billions of people through these tech industry partnerships. But they say the actions taken by the companies have not been enough and may even be problematic.

Vish Viswanath, a professor of health communication in the department of social and behavioral sciences at the Harvard T.H. Chan School of Public Health, has been closely monitoring the global health content spread by the tech industry since the pandemic started.

"The WHO deserves credit for recognizing that the sheer flood of misinformation the infodemic is a problem and for trying to do something about it," he says. "But the tech sector has not been particularly helpful in stemming the tide of misinformation."

Researchers say there are limits to some of the anti-misinformation tactics used by social media companies.

Flagging or pulling down a problematic social media post often comes too late to undo the harm, says Nasir Memon, professor of computer science and engineering at New York University. His research includes cybersecurity and human behavior.

"It only comes after the post has gone viral. A company might do a fact check and put a warning label," he says. "But by then the ones who consumed that information already have been influenced in some way."

For example, in October, President Donald Trump claimed in a Twitter post that he had COVID-19 immunity after he was sick. According to the CDC: "There is no firm evidence that the antibodies that develop in response to SARS-CoV-2 infection are protective." The post was taken off Twitter after being flagged by fact-checkers but not before it had been shared with millions of his followers.

And there are no guarantees that people are going to take the time to click on a link to credible sources to "learn more," as the labels suggest, says Viswanath.

These "learn more" and "for more information" COVID-19 labels can be found on almost every tech platform yes, Twitter, Facebook and Instagram, but also Tinder, the dating app (every few swipes there are reminders to wash hands and observe physical distancing, with links to WHO messages) and Uber, the ridesharing app (a section on its website with rider safety information directs people to WHO for pandemic guidance).

"If I'm sitting in some community somewhere, busy with my life, worried about my job, worried about whether the kids are going to school or not, the last thing I want to do is go to a World Health Organization or CDC website," Viswanath adds.

WHO is aware these measures aren't perfect. Melinda Frost, with WHO's risk communication team, concedes that simply removing posts can create new problems. She shares a December study from the disinformation analytics company Graphika. It found that the crackdown on anti-vaccine videos on YouTube has led their proponents to repost the videos on other video-hosting sites like BitChute, favored by the far-right.

YouTube removes videos if they violate its COVID-19 policy. Videos that claim the COVID-19 vaccine kills people or will be used as a means of population reduction, for example, are not allowed. But other platforms may have less stringent policies.

"We may expect a proliferation of alternative platforms as fact checking and content removal measures are strengthened on social media," Frost says.

Researchers say it's hard to know whether any of these efforts have actually changed people's behavior in the pandemic or encouraged them to turn to more credible sources.

Claire Wardle, U.S. director of First Draft, a nonprofit organization that researches misinformation, says "we have almost no empirical evidence about the impact of these interventions on the platforms. We can't just assume that things that seem to make sense [such as taking a post down or directing people to a trustworthy source] would actually have the consequences we would expect."

Andy Pattison, who leads WHO's digital partnerships in Geneva, says the organization is now trying to assess impact.

WHO is working with Google, for example, on a questionnaire for users to see whether the company's efforts have resulted in behavior change and/or increased knowledge regarding COVID-19. Since the early days of the crisis, Google has ensured that users searching for "COVID" or related terms on its search engine see official news outlets and local health agencies in its top results, says Pattison.

In the absence of current data, past research can shed some light on social media misinformation.

For example, an April 2020 study from the NYU Tandon School of Engineering found that warning labels messages such as "multiple fact-checking journalists dispute the credibility of this news" can reduce people's intention to share false information. The likelihood, however, varied depending on the participant's political orientation and gender.

Memon, the lead author of the report, says the findings are relevant to social media policing in the pandemic. "Fact checking [on social media platforms] is going to become an important aspect of what we do as a society to help counter the spread of misinformation," he says.

Both Memon and Viswanath say with tens of millions of posts being shared on social media a day, companies need to scale up efforts to take down false information.

"They have the power. They have the reach. They should be more aggressive and active than they have been," says Viswanath.

Memon suggests that companies could deploy stronger mechanisms to verify users' identities. That could help prevent people from creating troll accounts to anonymously spread falsehoods and rumors, he says. And Viswanath suggests that tech companies hire teams of experts ethicists, researchers, scientists, doctors for advice on how to handle false information.

As for WHO, it's learned a key lesson during the pandemic. "Information alone is not going to shift behavior," says Frost, who has been working on WHO campaigns to debunk unjustified medical claims on social media.

So over the past few months, the organization has been gathering a group of sociologists, behavioral psychologists and neuroscientists to study how information circulates, how it can be managed and how it can change people's minds.

"A lot of what we know about behavior change really requires something closer to the individual making sure the information we have is relevant to individuals and makes sense in their lives," she says.

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To Fight COVID-19 Misinformation, WHO Is Partnering With Big Tech : Goats and Soda - NPR

Participants Needed for a Health and Behavior Study – University of Arkansas Newswire

Are you interested in learning more about how behavior impacts your health?

The Center for Human Nutrition and the Exercise is Medicine program at the University of Arkansas are recruiting adults over the age of 18 years to participate in research related to health and behavior.

The DFEND (Diet, Food, Exercise, and Nutrition During social distancing) research study is a 20-week education program which involves 30-minute educational meetings once per week, weekly health and behavior challenges, and the opportunity to meet weekly with personalized coaches.

Compensation for full participation for the first 75 people to sign up. Anyone can join the DFEND educational sessions for free without signing up for the research study.

For more information, please contact us atbaum@uark.eduorDFEND@uaex.eduor go to our websitehttps://aaes.uark.edu/centers-and-programs/nutrition/dfend-3/.

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Falling In Love: Logan Ury Breaks It Down To A Science : Life Kit – NPR

Lucinda Schreiber for NPR

Lucinda Schreiber for NPR

Dating in a pandemic is no walk in the park. Well, actually, often it is literally a walk in the park but that doesn't mean it's easy. For over 15 years as a dating coach, people have come to me in a state of panic that their moment to find a match may have already passed.

I always try to convey to my clients that dating is a learned skill, with a step-by-step process and if you follow the plan, you will meet your future partner. Logan Ury has a plan and walks readers through every step of that process in her new book, How to Not Die Alone.

Not only is Ury a behavioral scientist for the dating app Hinge, she also has over a decade of experience studying human behavior at various technology companies, including Google.

In her book, Ury categorizes frustrated daters into three primary categories, and they each have unique challenges.

In her book, Ury spells out eight questions daters should ask after they meet someone. She says these questions can help people get in touch with how a date made them feel and stay away from a "checklist" dating mentality.

Each of these types has unique challenges and recommendations but some of Logan's advice is universal, regardless of your dating style. Here are three things you can do today to shift your love life for good:

Understanding your dating pitfalls and developing a strategy can help you move into the relationship you want. It might not come in the exact package that you envision, but a deep connection and relationship that can blossom over time is worth more than a million dead-end dates.

Damona Hoffman is a Certified Dating Coach and host of The Dates & Mates Podcast.

The podcast version of this story was produced by Meghan Keane.

We'd love to hear from you. Leave us a voicemail at 202-216-9823, or email us at LifeKit@npr.org.

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Datelines Keith Morrison Is Getting Used to Podcast Stardom – Vulture

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Photo: NBC Universal

After more than 50 years in the broadcasting business, there are still some surprises to be had for Keith Morrison, the dulcet-toned correspondent of NBCs long-running newsmagazine, Dateline. For instance, the success of his first podcast, 2019s The Thing About Pam, which hit No. 1 on Apple Podcasts and will soon be adapted by Blumhouse Television into a limited series starring Renee Zellweger.

I hadnt given much thought to the podcast world because we were busy enough as it was, says Morrison, who began his career in radio. I was somewhat skeptical at the beginning that this would be such a good fit for us, but once you realize that youre not constrained by all the structure of a television show, you can get more into the details and down the rabbit holes. It was fun.

So fun, in fact, that Morrison has decided to do it again. His new podcast Mommy Doomsday which follows the bizarre story of Lori Vallow, an Idaho woman whose two children went missing in 2019 and were later discovered dead on her husbands property in 2020 debuts February 16 with two episodes. (Check out the trailer here.)

Vulture recently spoke with Morrison about Mommy Doomsday, his initial reluctance about covering true crime, and the one case that he just cant seem to shake.

When you sit down to review the vast number of cases Dateline has covered over the years to select one for the podcast treatment, what criteria are you looking for?Keith Morrison: I think the principles of a good story are all the same It needs a strong character who people are amazed by and want to hear more about. And also things that happen that you wouldnt think could possibly happen. If you can allow people to imagine what might be coming next, and that what is coming next is really quite remarkable, then youve got a good story to tell. Im just talking about it in terms of storytelling, the morality of these things is quite another matter altogether.

Is it just coincidental that the two podcasts youve done so far have centered around crimes perpetrated by women?[Laughs] It is, totally. Although, I dont know whether it is safe to say such a thing, but some of the most interesting criminal minds you run across are the women. Im from Canada, and people used to say and maybe still do that We dont get as many murders in Canada, but theyre so interesting.

Keith Morrison. Photo: Patrick Randak/NBC

For those who are unfamiliar with the particulars of the Lori Vallow story, what can they expect out of this podcast?This is a story about a woman who had been having trouble getting stability in her life, who had kind of bounced from one thing to another, one husband to another, one difficulty to another. Shed always been a religious woman. She seized upon a religious crusade that would give her some real purpose in her life, but it went off the rails, and it left bodies in its wake. Were still investigating just how many bodies that may be.

To your point, investigations are still pending, so her story really isnt finished. How then do you craft a compelling conclusion for listeners?I fully anticipate that therell be another trial before too long and would already have been by now, had it not been for COVID. [Vallows trial for misdemeanor charges is slated for August 30.] So you can leave things in advance as long as listeners or viewers kind of understand whats what and whos who and what happened. You dont have to see them carted off to prison. It sounds so cold. Its a weird thing. Can I back up for just a second?

Of course.Getting into this line of work, this storytelling about true crime, was not an easy thing for me. I had covered all kinds of stuff for a long time in Canada and the U.S. daily news for NBC Nightly News and the Today show and long-form documentaries on NBC, but also on the CBC for years covering politics mostly, but other stuff, lots of stuff, and I enjoyed it immensely.

And when true crime sort of took over the genre of long form in America, I was one of the early resistors. I didnt want to do it. I just thought, What? Its almost like youre intruding into a process, which its our right to intrude and look into it and see what happened. But I wasnt sure it was a good thing for us to do, necessarily. But as I have done it, it not only opens a window on human character, that is probably a uniquely suited way to get there. I dont know of any other way to get to the heart of what makes a human being, a human being. To dive deeply into a criminal matter that a person has been involved in. And the victims of these murders or whatever they happened to be, the families of those people, we dont talk to them unless they want to talk to us. If they want their privacy, we give them their privacy. But we find more often than not, theyre happy to do so. That its cathartic for them. That its a way to honor and celebrate the life that was lost. And so I feel better about it, but I will say, I never expected to be quite so fascinated about the many and varied facets of human behavior. How were all strange little ducks inside somewhere.

I feel like shows such as Dateline give viewers a level of transparency about the justice system that we maybe wouldnt get otherwise.Yes, I agree. Ive learned lots of things about the justice system I wasnt aware of.

You just celebrated your 25th year with Dateline. Im curious if, in all this time, youve developed a BS meter for when people are lying to you?Maybe to some degree. I was fascinated by the study that came out years ago on this very question. I interviewed this guy, and hed done a lot of research, and the evidence shows that an average college student can detect lying with a somewhat better average than the average detective whos been working in homicide cases. The research speculated that the reason for that is simply that the homicide detective thinks he can identify a lie, therefore hes apt to make mistakes when listening to the answers. Really, human beings are incredibly good at lying and not very good at determining when theyre being lied to. I think thats a large part of the reason people are so fascinated by true crime, because they are in a world where you dont know whos telling you the truth and you want to find out.

So would you say youre in between a college student and a detective?[Laughs] Im probably the worst of those.

Speaking of your long tenure at Dateline, is there one case youve covered that stands out as the most memorable one you just cant shake?Thereve been so many, there really have. The one I think about, its a story that really, nobody knows and hasnt been particularly celebrated outside of classrooms where they teach about it in some universities. It was a case the Innocence Project took up and never got the result they were hoping for.

The case involved a man named Billy Wayne Cope, who lived in a small town in South Carolina. His daughter was murdered and sexually assaulted one night, and Billy Wayne had been in the house. He called 911, and they decided he mustve done it. And though he denied it endlessly 666 times, his attorney would later say he eventually caved. He was not a terribly bright man, but he was a very sweet fellow. He was charged with the murder. He finally confessed. But a month later, they identified the DNA that was found in his daughter [from] another crime that occurred a block or two away from where he lived. And the person who was caught for that crime, it was clear as day that he also committed this crime. I mean, he left DNA in both of those people. But instead of absolving Billy Wayne Cope and charging the other guy, they charged him with conspiracy and tried them both, and accused Billy Wayne of helping him and watching, and being an even worse villain for that, even though theyd never met each other before. And so it was a total bogus case and he was convicted, sent away for life. All the efforts of all the Innocence Projects that got involved, because they wanted to free this innocent man, came to nothing and he eventually died in prison. So its a very, very sad story, but one that I cant shake. I think about it a lot.

Ive always been a fan of Dr. Seuss. One of my favorite books of his is Horton Hears a Who!, and the reason is because it exemplifies whats good about the justice system. A persons a person, no matter how small and is entitled to equal justice under the law. And that, I think, drives a lot of people who are in that line of work, that they would like to see justice achieved for everybody. And its a terribly imperfect system, but I think thats the goal people have, and the thing that gives emotional heft to a lot of stories, like the one about Billy Wayne Cope.

Listening notes for the top shows, from Vulture's critic Nick Quah.

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Datelines Keith Morrison Is Getting Used to Podcast Stardom - Vulture

Love is in the air with Oatland wildlife center birds – Savannah Morning News

Eric Swanson| For Savannah Morning News

Musician John Paul Young once wrote Love is in the air, everywhere I look around. Love is in the air, every sight and every sound. As Valentine's Day approaches, the same could be said for the animals at Oatland Island Wildlife Center. While romantic love is debated as purely a human emotion, the rituals and behaviors of animals can be easily confused for love. So, since love is in the air, we thought we would take this opportunity to share some facts about the birds (but not the bees!) that call Oatland home.

Bird courtship rituals can look like human dating, with some species singing or dancing to impress a mate, others putting on flashy outfits by molting into bright feathers, still others provide tasty morsels to eat. The male Carolina wrens take things a bit further, asking females to move right in and start a family, building multiple nests to woo their partner. The building process and home showings display both their building skills as well as their excess energy which cues potential mates that they are successful food foragers.

At Oatland, the Carolina wrens have been seen building their nests, and it won't be long until we see females diligently incubating eggs. Listen for their loud teakettle, teakettle, teakettle call next time you visit, and you might spot them!

More: Match beak to food to boost your bird-watching buck

Owls are winter nesters and hoot wildly from high perches to maintain and define territory, which is then controlled by a bonded pair. They work together to find a suitable place to lay eggs, like a tree cavity or an abandoned nest, the male striving to impress the female by bringing her small rodents to eat. Owl species cooperate to raise their young with each member of the pair providing incubation and food.

For years, our barred owl, Wahoohoo, has laid one or two eggs within a week of Valentines Day. With no male present in the enclosure the eggs are always infertile, but she still heeds the biological cue to lay an egg every winter. Listen for the easy-to-remember barred owl hooting, Who cooks for you? Who cooks for you-all? and the great horned owl making a deep but soft hoo-ha HOO-hoo-hoo.

More: Find stars used on the underground railroad with Oatland Island astronomy night

If you have walked past the Oatland eagles recently you may have noticed two white eggs peeking up from their nest. Eagle eggs take approximately 35 days to incubate, with the female eagle minding the nest and tenderly turning the eggs with her beak. In the wild, many Southern bald eagle chicks hatch out near Valentine's Day. While our bald eagle pair, Arnold and Francesca, do appear to have bonded and tolerate each other's presence year-round (a rarity in the wild), the eggs laid every January have so far been found to be infertile. Whether the infertility is due to the human-made match or because of their poor balance due to past wing injuries, we can only speculate.

So, do bald eagles love? They do mate for life and return year after year to the same nest which takes a lot of commitment, so we will let you decide.

From flashy feathers to nest-building, a lot of bird behavior is driven by the biological urge to perpetuate their genes. In nature, if you have the skills to survive, your genes are valuable. While that simplification may not seem romantic for a pairing in human society, in the animal kingdom it is what matters the most. So this Valentines Day, though you may don your nicest clothes and secure a delicious meal for your partner, dont forget to delight in the human experience of conversation and connection. And, if youre looking for a great date idea, come check out the animal couples at Oatland Island Wildlife Center.

Eric Swanson is a naturalist at Oatland Island Wildlife Center. Learn more atoatlandisland.orgor on Facebook atoatlandisland.

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Love is in the air with Oatland wildlife center birds - Savannah Morning News

Think forecasting COVID in Colorado was tough in 2020? It will be tougher in 2021, experts say – coloradopolitics.com

A mix of policy and behavior helped Colorado dodge a bullet late last year, contributing to a cumulative 2020 COVID-19 death count far below some of the worst-case scenarios predicted by the state's modeling team in the fall, one of its members says.

But were other factors at play? Was the modeling off? Did Colorado buckle down on preventative measures in the nick of time? Was it sheer luck or perhaps a mix of factors?

It's impossible to say precisely, experts contend. But one thing is certain: The job of those who attempt to forecast the pandemic hasn't gotten any easier in the new year, given nascent variables such as the vaccine rollout and the development and spread of mutations.

Infectious disease epidemiologists are "trying to change their shoes while riding a bicycle in the middle of a hurricane," saidDr. Elizabeth Carlton, assistant professor at the Colorado School of Public Health and member of the state's COVID-19 modeling team,a multidisciplinary team comprised of experts at colleges and universities throughout the state.

Says Dr. Phoebe Lostroh, a Colorado College microbiology professor with a history of highly accurate El Paso County virus projections: "It's just as complicated as forecasting the weather, if not more so."

Wildcard: Human behavior

COVID directly caused 4,215 deaths in Colorado last year less than a quarter of one of the worst-case scenarios proffered by the state's coronavirus modeling team last fall, according to preliminary data released Friday by the state that is expected to be finalized later this spring.

A Dec. 4 report from the state's COVID-19 modeling group warned that deaths could reach as high as 7,650 by the end of the year if the state saw an 11% reduction in transmission control a measure that monitors how well Coloradans are adhering to pandemic-related behavior and policy changes and a 30% drop in social distancing due to the holidays. At the time, it was on track for 5,600 deaths.

An Oct. 28 report, just 15 days ahead of the state's all-time high in new daily diagnoses, warned that Colorado's death toll could reach as high as 17,500 by the end of 2020 with a decrease in transmission control due to the holidays. At the time it was on track for 7,600 deaths.

Explanations for the lower-than-expected death toll are complex, involving a mix of factors like policy, behavior, politics and perhaps even factors like climate and the health of Coloradans prior to the pandemic.

"We don't generate forecasts, we generate projections," Carlton said "what if" scenarios for a multitude of factors including how quickly the virus is spreading and how well Coloradans are complying with transmission-control measures.

As to why the state's COVID death toll came in lower than anticipated, "the week before Thanksgiving we saw this dramatic reduction in the amount of population mixing and the contacts people where having," she said.

Consequently, hospitalizations began to fall by early December, and deaths followed suit, with the usual lag of a couple of weeks.

"It was some combination of policy and behavior that started sometime in late November, and we're in a much better place because of it," she said.

Lostroh's take: "The worst-case scenarios took into account the worst possible choices, and I don't think we made all of those," she said, speaking of Coloradans on a whole.

The models being produced on a state level are "so much more sophisticated than what I'm doing," Lostroh said, adding that longer-term forecasting, versus the week-by-week forecasting she does, is "inevitably more inaccurate."

The Harvard grad's modeling is based off of two "very simple assumptions": One, that the "virus is spreading exponentially," and two, that "every infected person infects, on average, more than one other person."

Assuming human behavior isn't changing, "when these two things are true, my forecast has been accurate, for weeks and weeks," Lostroh said. "When either is not true, it's no longer as accurate."

The biggest wild card in modeling, Carlton contends, is humans behavior.

"I think the hardest thing to predict in any model is how people are going to behave," Carlton said. "It's much easier to predict how the virus is going to behave."

A race between vaccine, variants

To make matters more complicated, there are new variables that weren't present a couple of months ago. For one, there's the vaccine rollout, contributing to a rising herd immunity. And then there are variants like the highly transmissible and potentially more lethal B.1.1.7, which triggered alarm when announced by U.K. officials in December and caused strict lockdown measures in southern England. There is also L452R, first seen in Denmark last spring and recently linked to several large-scale outbreaks in California.

Both have been found in Colorado, though only 33 variant cases had been identified in the state, with 13 cases under investigation. Only 30% of the state's positive cases are being screened for the B.1.1.7 variant, and genome sequencing to confirm it is only performed on approximately 3% of positive tests statewide, state health officials cautioned in a Friday news release.

"One of the challenges for any modeling team is responding in real time" to changing factors, Carlton said. Are COVID patients spending less time in the hospital? Are deaths dropping due to advancements in treatment? What mutations are present in Colorado, and how rapidly are they spreading?

The state's COVID modeling team is now building vaccination scenarios into its models, she said, as well as variant scenarios. But both are a "moving target."

For instance, it's unknown how rapidly the B.1.1.7 variant is spreading in the state.

"Right now it looks like in Colorado it's not spreading very rapidly," she said, adding that in the U.K., the variant "held at low levels for several months and then increased very rapidly."

Why would it spread so rapidly there and not here?

"I've been banging my head against the wall, trying to figure it out," she said.

The further ahead one tries to forecast, "the more uncertainty you have and the more you have to make educated guesses," Lostroh said.

But one thing is fairly certain.

"I think it's a race between the spread of that variant and vaccinating people," she said.

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Think forecasting COVID in Colorado was tough in 2020? It will be tougher in 2021, experts say - coloradopolitics.com