Cell Biology

New York axes stem cell funding in this year’s budget – BioEdge

In 2007, defying the conservatism of the Bush Administration, New York State created a fund for research on stem cells, including human embryonic stem cells. The New York State Stem Cell Science program (NYSTEM) was smaller than Californias US$3 billion program, but still substantial, at $600 million over 11 years.

However, it has been quietly dropped in the States current budget.

NYSTEM funded a lot of important work that would not have happened otherwise, says stem cell researcher Sean Morrison of the University of Texas Southwestern Medical Center, in Dallas. The termination of the program is a setback for New York state and for the field of stem cell biology as whole.

According to Science, Researchers expect the termination to be especially harmful to the study of human embryonic stem cells.

However, the program has experienced serious problems in recent years and has only distributed $400 million so far.

In 2016, its board stopped meeting and reporting expenditures on its website, and since then awards have been inexplicably delayed: Researchers who applied in 2016 say they received money only in 2018 after several meetings in the governors office. And those who applied for last years grantswhich were expected to support up to 70 projects with $50 million over 3 yearssay they never received any official response.

Perhaps the States budget is just too tight in the Covid-19 era. A government official told Science that stem cell science should advance within academic and private research communities rather than the Department of Health, which is focused on its core mission of delivering direct services and achieving positive health outcomes for all New Yorkers.

Michael Cook is editor of BioEdge

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New York axes stem cell funding in this year's budget - BioEdge

Cell Biology

New human biology major to be offered starting fall 2021 – The Aggie

Professors Aldrin Gomes and Ken Kaplan give insight into the majors unique opportunities and subject matter

The new human biology major is currently only open by lottery to College of Biological Sciences students who entered UC Davis as freshmen and have met other requirements detailed on the majors website200 students will be admitted into the major starting fall 2021.

Professor Ken Kaplan, the vice-chair of the Department of Molecular and Cellular Biology, and Professor Aldrin Gomes co-created the major, which will be offered to students with second-year status. According to Kaplan, human biology is a topic central to biological sciences that hasnt been given a sufficient platform at UC Davis.

A lot of us in biology think all the time about human biology whether we study model organisms or not, so its central to how we think, and I think theres a recognized need to help students see that, Kaplan said. [Weve] got micro[biology] majors, neurobiology majors and cell biology majors and they all study different organisms, but this is an opportunity to really focus our teaching on human systems in a way that we havent had a chance to do.

Jasmine Taros, a second-year biological sciences major, said she had been considering other majors as she approached her third year at UC Davis and wished she could apply to a major that involved the human side of biology.

I was thinking about cell bio and I was even thinking to myself, I wish they had a human bio major, because ever since a young age, Ive always liked bio but [] always liked the chapters that have to do with the human bio rather than the plant part, Taros said.

Professor Aldrin Gomes, the vice-chair of the neurobiology, physiology and behavior (NPB) major, believes that the new major will allow students to take more diverse biology classes than other majors in the college.

We wanted something where students can actually have access to anything in other majors that they thought [was] very useful for them going forward, Gomes said. For example, in a microbiology lab, if a student was only an NPB major, [] it wouldnt give credit toward [their] major, Gomes said. Now, they can still do things like that and get credit toward the major.

One of Kaplans motivations for wanting to implement the human biology major was that it integrates a wide array of laboratory subjects, whereas labs in other College of Biological Sciences majors have a more narrow focus.

To me, one thing thats super exciting is that now, students can satisfy their laboratory requirements [] choosing from this menu of really exciting laboratory courses that span microbiology, biochemistry, physiology, Kaplan said. Theres just so many opportunities for them to pick from these laboratory choices that they may not have had access to before.

As a part of most majors within the College of Biological Sciences, students will take certain upper-division restricted electives pertaining to their major. According to Kaplan, the new majors restricted electives will incorporate both the natural science and social science concepts necessary to understand human biology.

We will have courses from anthropology introduced as one of those restrictive electives, so not only do they get courses that were used to teaching here, but theyre going to get exposed to human biology from different perspectives across the university, Kaplan said. My vision is that we continue to work on bringing in those kinds of courses from outside because human biology is more than just the molecules and the genes and the proteins and the organs, its also how it affects society, [] medicine and policy.

Gomes said that he and Kaplan plan to increase the number of students in the major after five years.

The tentative plan was for five years at a cap of 200 because we want to give a good experience to students and if problems arise, we want to be able to handle it and get a well-oiled major before we start to let everyone who wants to do it in, Gomes said.

Gomes and Kaplan plan to continue revising the major as it progresses.

It allows us now to leverage the strengths of all the departments instead of just one department to really create something that is like a live-in document which you continue to improve, and in future years, were actually thinking about specific courses to add that will add value to the major, Gomes said.Written by: Lyra Farrell features@theaggie.org

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New human biology major to be offered starting fall 2021 - The Aggie

Cell Biology

High-yield topics and the MCATwhat pre-meds should know – American Medical Association

In preparing for the Medical College Admission Test (MCAT), studying high-yield topicsthose that appear most frequently in the exams four sectionscan pay dividends.

"The mistake test-takers make is they tend to want to treat everything equally, not realizing that there is a proportions game that comes into play," said Petros Minasi, Kaplan's senior director of pre-health programs. "Pre-med students should be strategic on where they are putting their emphasis."

Still, defining which topics qualify as high-yield and how to best cover them is tricky. An expert on MCAT prep, Minasi offered his insight.

What are the high-yield topics?

Certain topics are simply more commonly tested than others. Minasi offered a listbased on Kaplans experience with the examby the types of sciences the exam covers.

These largely apply to three MCAT sections: biological and biochemical foundations of living systems; chemical and physical foundations of biological systems; and psychological, social and biological foundations of behavior. The critical analysis and reasoning skills (commonly referred to as CARS) is largely based on inference.

Biological sciences: Biochemistry of proteins, enzymes, amino acids, DNA, molecular biology, oxidative phosphorylation, and general cell biology.

Physical sciences: Thermodynamics, chemical reactions, oxidation reduction, and acids and bases.

Physics: Kinematics, forces, work, torque, waves and electrostatics.

Behavior sciences: Learning and memory, demographics, social behavior and group psychology.

Additional tidbits

Cover the basics. Some of the topics above are more advanced concepts, but to truly understand them, youll need to cover the basics.

"Some topics might not be directly tested at higher yield, but are indirectly tested. A perfect example for this is organic chemistry. While there are some questions on the MCAT that test organic chemistry directly, there are a lot of questions, particularly in biochemistry, that require a strong working knowledge of it in order to get the questions correct."

Topics alone arent enough. "Students need to build a study plan that includes all of the scientific topics, with extra emphasis on the higher yield topics, but will also want to practice the critical thinking skills that are simultaneouslytested on the MCAT," Minasi said.

Practice makes perfect. The AMA and Kaplan have collaborated on a library of MCAT stumpers that can help pre-meds prepare for the exam. TheAMA pre-med glossary guidehas the answers to frequently asked questions about medical school, the application process, the MCAT and more. Kaplan also offers free study plans for prospective test takers.

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High-yield topics and the MCATwhat pre-meds should know - American Medical Association

Cell Biology

Update Report on Global Cell Biology Test Kits Market 2021, Analysis by Types, Application and Key Manufacturer- Thermo Fisher Scientific, Bio-Rad,…

Report Overview

This report regarding the Cell Biology Test Kits market studies the latest trends prevalent in the industry covering the overall market with an exhaustive analysis. This includes quantitative and qualitative assessment of a market with the results used to study the market growth. The market overview contained in this report gives the market definition along with the product specifications and applications. It also contains information on the manufacturing methods prevalent in the Cell Biology Test Kits industry.

The market data collected from the period 2021-2027 has been used to scrutinize the market analysis in terms of the specific market movements regarding the markets overall progression.

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Major Players are- Thermo Fisher Scientific, Bio-Rad, PromoCell, Merck, Universal Biologicals, PerkinElmer, TaKaRa, Promega, MOLECULAR DEVICES, NanoEntek, BIOQUOCHEM, and Bio Basic

Global Cell Biology Test Kits Market Dynamics:

The report begins with a market overview and moves on to cover the growth prospects of the Cell Biology Test Kits market. A detailed segmentation analysis of the Cell Biology Test Kits market is available based on manufacturers, regions, type, and applications in the report. The analysis also covers upstream raw materials, equipment, downstream client survey, marketing channels, industry development trend, and proposals.

The report focuses on the Cell Biology Test Kits in the global market, especially in North America(U.S., Canada, Rest of North America), Europe(UK, Germany, France, Italy, Spain, Rest of Europe), Asia Pacific(China, Japan, India, Southeast Asia, Rest of Asia Pacific), Latin America(Brazil, Argentina, Rest of Latin America), Middle East and Africa(GCC Countries, South Africa, Rest of the Middle East & Africa)

This report also presents product specification, manufacturing process, and product cost structure, etc. Production is separated by regions, technology, and applications. Other important aspects that have been meticulously studied in the Cell Biology Test Kits market report is Demand and supply dynamics, import and export scenario, industry processes and cost structures, and major R&D initiatives. In the end, the report includes Cell Biology Test Kits new project SWOT analysis, investment feasibility analysis, investment return analysis, and development trend analysis.

Method of Research

The research conducted by the team working on the report has been done in a qualitative and quantitative manner to present a comprehensive study of the market and statistics. The research looks into the different aspects of the market while conducting primary and secondary research. The study also comprises of a company analysis carried out to evaluate securities, collect business information and study the companys profile, products, and services. The other research methodologies adopted also include a framework of macro-environmental factors used in the environmental scanning component of strategic management. Apart from Porters Five Forces analysis and SWOT analysis to study the competitive landscape, PEST analysis has been conducted to examine the opportunities and threats due to Political, Economic, Social, and Technological forces.

Questions are answered in Cell Biology Test Kits Market report:

All of these questions are answered using industry-leading techniques and tools as well as a vast amount of qualitative research.

Regional Analysis

The region-wise study conducted by the report looks into the key market indicators and factors affecting each regional market. The regional analysis has categorized the production, apparent consumption, export and import in the major regions covering all the key countries. In order to present the Cell Biology Test Kits market landscape coverings the consumer and commercial markets have been analyzed. The report also covers the manufacturers in these regions regarding the manufacturing sites, capacity, production, ex-factory price, revenue, and market share in the global market. The report provides a comprehensive outlook presenting the market prospects and forecast for the period 2021-2027.

Table of Contents: Cell Biology Test Kits Market

Chapter 1: Overview of Cell Biology Test Kits Market

Chapter 2: Global Market Status and Forecast by Regions

Chapter 3: Global Market Status and Forecast by Types

Chapter 4: Global Market Status and Forecast by Downstream Industry

Chapter 5: Market Driving Factor Analysis

Chapter 6: Market Competition Status by Major Manufacturers

Chapter 7: Major Manufacturers Introduction and Market Data

Chapter 8: Upstream and Downstream Market Analysis

Chapter 9: Cost and Gross Margin Analysis

Chapter 10: Marketing Status Analysis

Chapter 11: Market Report Conclusion

Chapter 12: Research Methodology and Reference

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In conclusion, it is a deep research report on the global Cell Biology Test Kits industry. Here, we express our thanks for the support and assistance from Cell Biology Test Kits industry chain related technical experts and marketing engineers during Research Teams survey and interviews.

If you have any special requirements, please let us know and we will offer you the report as you want.

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Update Report on Global Cell Biology Test Kits Market 2021, Analysis by Types, Application and Key Manufacturer- Thermo Fisher Scientific, Bio-Rad,...

Cell Biology

Top Key-Players To Be Restored To The First Position In The Recombinant Cell Culture Supplements Market The Courier – The Courier

The Recombinant Cell Culture Supplements Market report by Persistence Market Research is focusing on the fact that healthcare providers are into collection of socioeconomic information of the patients, so that tracking at any point of time is possible. This on-the-go monitoring is amongst the ongoing trends in the healthcare industry.

Adoption of recombinant cell culture supplements by biopharmaceutical manufacturers and research institutes has increased significantly for the development of novel drugs and treatment. Growing demand for novel vaccines to treat and prevent severe diseases, as well as increasing stem cell research activities by biopharmaceutical manufactures are likely to pace up the lucrativeness of theglobalrecombinant cell culture supplements market.

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Company Profiles

Recombinant cell culture supplements are gaining higher adoption in mammalian cell production processes in different production units and research centres. Moreover, rising investments in biologics production and growing research for the introduction of innovative gene therapies are bolstering the demand for recombinant cell culture supplements.

The global recombinant cell culture supplements market was valued aroundUS$ 320 Mnin2018, and is expected to exhibit aCAGRof more than6%over the forecast period (20192029).

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Key Takeaways of Recombinant Cell Culture Supplements Market Study

Increasing requirement of recombinant cell culture supplements for mammalian cell lines and viral & protein-based vaccines production is likely to pace up market growth. Demand will continue to pick pace, with burgeoning use of supplements in cancer research, tissue regeneration, and gene therapy development,says a PMR analyst.

Product Portfolio Expansion through Acquisitions & Partnerships Key Strategy of Manufacturers

Recombinant cell culture supplement manufacturers are focusing on product portfolio expansion through partnerships and acquisition of small. In 2015, Abcam Plc signed an exclusive partnership agreement with A* STARs Institute of Molecular and Cell Biology to develop high-quality immunoassays for life science research.

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More Valuable Insights on Recombinant Cell Culture Supplements Market

Persistence Market Research offers a unique perspective and actionable insights on recombinant cell culture supplements in its latest study, presenting historical demand assessment of20142018and projections for20192029, on the basis of product (recombinant growth factors, recombinant insulin, recombinant albumin, recombinant transferrin, recombinant trypsin, recombinant aprotinin, recombinant lysozyme, and others), application (stem cell therapy, gene therapy, bioprocess application, vaccine development, and others), source (animals, microorganisms, and humans), and end user (academic and research institutes, biopharmaceutical companies, cancer research centers, and contract research centers), across seven major regions.

Explore Extensive Coverage of Persistence Market Researchs Healthcare Industry

About us:

Persistence Market Research (PMR), as a 3rd-party research organization, does operate through an exclusive amalgamation of market research and data analytics for helping businesses ride high, irrespective of the turbulence faced on the account of financial/natural crunches.

Contact us:

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Top Key-Players To Be Restored To The First Position In The Recombinant Cell Culture Supplements Market The Courier - The Courier

Cell Biology

Axion BioSystems Announces Formation of Scientific Advisory Board – Business Wire

ATLANTA--(BUSINESS WIRE)--Axion BioSystems, a leading life science tools company focused on developing and commercializing label-free, bioelectronic assays used to study the function of live cells in vitro, announces the formation of a Scientific Advisory Board (SAB). The SAB will be chaired by Jim Ross, Ph.D., founder and Chief Technology Officer, and will work closely with Axion BioSystems management team to help identify and prioritize Axions next generation of bioelectronic products.

We are proud to have such an accomplished and diverse group of scientific experts joining our Scientific Advisory Board. The SABs expertise will be invaluable as we continue expanding our research and development activities, said Tom OBrien, CEO & President of Axion BioSystems.

The members of Axion BioSystems Scientific Advisory Board include:

Christopher Basler, Ph.D., is Professor and Director of the Center for Microbial Pathogenesis at Georgia State University. He obtained his Ph.D. from Albert Einstein College of Medicine in 1995. He became Professor of Microbiology at Icahn School of Medicine at Mount Sinai in New York City in 2013 and moved to Georgia State University in 2016. Dr Basler was elected Fellow of the American Academy of Microbiology in 2014 and was named a Georgia Research Alliance Eminent Scholar in Microbial Pathogenesis in 2016. His major research interests are understanding immune evasion and replication mechanisms of filoviruses, coronaviruses and other emerging RNA viruses.

Evangelos Kiskinis, Ph.D., is an Assistant Professor of Neurology at Northwestern University Feinberg School of Medicine, Director of the Stem Cell Core Facility, and a New York Stem Cell Foundation Robertson Investigator. He received Ph.D. from Imperial College and carried out postdoctoral training at Harvard University where he pioneered the first models of ALS using personalized stem cell-based approaches. Dr Kiskinis discoveries on excitability deficits in patient neurons using induced pluripotent stem cells (iPSCs) led to a clinical trial with a small molecule drug. His laboratory seeks to harness the power of pluripotent stem cells to understand how neuronal function is impaired in ALS/FTD patients and pediatric forms of epilepsy. He has been the recipient of prestigious fellowships from the European Molecular Biology Organization, the New York Stem Cell Foundation and the Charles A. King Trust Medical Foundation.

Alysson Muotri, Ph.D., is a Professor at the Departments of Pediatrics and Cellular & Molecular Medicine at UC San Diego. He is also the Director of the Stem Cell Program and Archealization Center at UCSD. His lab focuses on the re-creation of the human brain using stem cell technologies and brain organoids. Dr. Muotri received his Ph.D. in Genetics in 2001 from University of Sao Paulo, Brazil, and moved to the Salk Institute as Pew Latin America Fellow in 2002 for postdoctoral training in the fields of neuroscience and stem cell biology. His research focuses on brain evolution and modeling neurological diseases using human induced pluripotent stem cells and brain organoids. He has received several awards, including the prestigious NIH Directors New Innovator Award, NARSAD, Emerald Foundation Young Investigator Award, Surugadai Award, Rock Star of Innovation, NIH EUREKA Award, Telly Awards among several others.

Manu Platt, Ph.D., is a Professor at the Wallace H. Coulter Department of Biomedical Engineering at Georgia Institute of Technology & Emory University. He received his Ph.D. from Georgia Tech/Emory joint program in Biomedical Engineering, and carried out postdoctoral training at MIT. Currently, his lab focuses on pediatric strokes in sickle cell disease and personalized and predictive medicine strategies for breast cancer. Dr Platts work has been successfully funded by NIH Directors New Innovator Award, International AIDS Society, Georgia Cancer Coalition, and the National Science Foundation. Dr. Platt was inducted as inducted as a Fellow of the American Institute for Medical and Biological Engineering (AIMBE) in 2019. Integrated with his research program are his mentoring goals of changing the look of the next generation of scientists and engineers to include all colors, genders, and backgrounds. Aligned with that goal, Dr. Platt co-founded Project ENGAGES (Engaging the Next Generation At Georgia Tech in Engineering and Science), with Dr. Bob Nerem in 2013.

Jiwen Zhang, Ph.D., is Vice President of Regulatory Affairs at Passage Bio, Inc. Before joining Passage Bio, she had worked at Tmunity, GE Healthcare and biopharmaceutical companies including Johnson & Johnson, Merck, Wyeth Pharmaceuticals, and Sanofi-Aventis. Dr. Zhang has extensive experience in regulatory development across multiple therapeutic areas, including anti-inflammatory, anti-viral, metabolic, hematology, bone and growth. She has also had experience in developing drug/device combination products, and medical devices used at cell therapy point of care setting. She is leading various industry initiatives through the Standards Coordinating Body, the International Standards Organization (ISO), CASSS, and Asia Pacific Economic Cooperation Regulatory Harmonization Steering Committee (APEC RHSC). Dr. Zhang obtained her Ph.D. in Neuroscience from the joint program at the Rutgers University and the University of Medicine and Dentistry of New Jersey.

For more information, please visit https://www.axionbiosystems.com/scientific-advisory-board.

About Axion BioSystems, Inc.

Axion, a life science company located in Atlanta, GA, developed the first commercial multi-well MEA system, the Maestro, an easy-to-use, non-invasive instrument that measures functional electrical signals from brain and heart cells. Axion have continued to expand on the promise of these label free, bioelectronic assays. Recently, Axion introduced the Maestro Z and ZHT systems, providing functional measures of cell growth, with specific applications in immuno-oncology and virology. Axions products are used by pharmaceutical and biotech companies, governmental agencies, and universities for disease modeling, drug safety, and drug discovery assays.

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Axion BioSystems Announces Formation of Scientific Advisory Board - Business Wire

Cell Biology

Tissue Repair, Mitochondrial Function and Wound Healing Explored in 2021 APS Presidents Symposium – Newswise

Rockville, Md. (April 22, 2021)Top researchers in physiology will present a three-part series exploring cellular regulation of mitochondrial function, tissue repair and wound healing. The symposia are organized by American Physiological Society (APS) President Linda Samuelson, PhD, FAPS, FAAAS, of the University of Michigan. The APS Presidents Symposium Series will be part of the APS annual meeting at Experimental Biology 2021, which will be held on a virtual platform April 2730.

Function Symposium: Regulation of Physiological Function

Tuesday, April 27, 2 p.m. Virtual Session, Room APS-1

Chair:Ole H. Petersen, CBE, FRS, Cardiff University, U.K.

Speakers:

Functions of presynaptic voltage-gated calcium channels

Annette Dolphin, PhD, FRS, FmedSci, University College London, U.K.

Crosstalk between Ca2+ and cAMP signaling in mitochondria: where, when, why

Tullio Pozzan, MD, FRS, University of Padova, Italy

New perspectives on the physiological roles of KATP channels

Colin Nichols, PhD, FRS, Washington University School of Medicine, St. Louis

The P2X7 receptor is a key modulator of mitochondrial energy metabolism

Francesco Di Virgilio, MD, University of Ferrara, Italy

Adult Cell Plasticity and Tissue Rejuvenation

Wednesday, April 28, 2 p.m. Virtual Session, Room APS-1

Chair: Linda Samuelson, PhD, FAPS, FAAAS, University of Michigan

Speakers:

Switching cell fate to regenerate liver

Stacey S. Huppert, PhD, Cincinnati Childrens Hospital

Exercise rejuvenates aging stem cells

Thomas Rando, MD, PhD, Stanford University, Stanford, California

Cellular remodeling via paligenosis

Jason C. Mills, MD, PhD, Washington University School of Medicine, St. Louis

Cellular Cross-talk to Orchestrate Tissue Repair

Thursday, April 29, 2 p.m. Virtual Session, Room APS-1

Chairs: Linda Samuelson, PhD, FAPS, FAAAS, University of Michigan; Jason C. Mills, MD, PhD, Washington University School of Medicine, St. Louis

Speakers:

Immune mediators and wound healing

Asma Nusrat, MD, University of Michigan

Mesenchymal cells promote lung regeneration

Edward E. Morrisey, PhD, Perelman School of Medicine, University of Pennsylvania

Tissue stem cells: coping with stress

Elaine Fuchs, PhD, Howard Hughes Medical Institute, The Rockefeller University, New York

NOTE TO JOURNALISTS: To schedule an interview with a member of the research team, please contact the APS Communications Office or call 301.634.7314. Find more research highlights in the APS Newsroom.

About Experimental Biology 2021

Experimental Biology is the annual meeting of five societies that explores the latest research in physiology, anatomy, biochemistry and molecular biology, investigative pathology and pharmacology. With a mission to share the newest scientific concepts and research findings shaping clinical advances, the meeting offers an unparalleled opportunity for global exchange among scientists who represent dozens of scientific areas, from laboratory to translational to clinical research.

About the American Physiological Society

Physiology is a broad area of scientific inquiry that focuses on how molecules, cells, tissues and organs function in health and disease. The American Physiological Society connects a global, multidisciplinary community of more than 10,000 biomedical scientists and educators as part of its mission to advance scientific discovery, understand life and improve health. The Society drives collaboration and spotlights scientific discoveries through its 16 scholarly journals and programming that support researchers and educators in their work.

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Tissue Repair, Mitochondrial Function and Wound Healing Explored in 2021 APS Presidents Symposium - Newswise

Cell Biology

Global Cell Therapy Market By Therapy Type, By Therapeutic Area, By End User, By Cell Type, By Regional Outlook, Industry Analysis Report and…

The Global Cell Therapy Market size is expected to reach $28. 5 billion by 2026, rising at a market growth of 26. 2% CAGR during the forecast period. Cell therapy is considered as a technology that is based on substituting dysfunctional or diseased cells with active & functional cells.

New York, April 22, 2021 (GLOBE NEWSWIRE) -- Reportlinker.com announces the release of the report "Global Cell Therapy Market By Therapy Type, By Therapeutic Area, By End User, By Cell Type, By Regional Outlook, Industry Analysis Report and Forecast, 2020 - 2026" - https://www.reportlinker.com/p06064792/?utm_source=GNW Stem cells possess the capability to differentiate into particular cells needed for repairing damaged or defective tissues or cells, thats why they are utilized for these advanced therapies. In addition, cell therapy is used in the development of regenerative medicines, which is an interdisciplinary domain aimed at maintenance, enhancement, or restoration of cell, tissue, organ function with the help of procedures majorly associated with cell therapy.

Moreover, cells like bone marrow and blood cells, mature, immature & solid tissue cells, adult stem cells, and embryonic cells are extensively deployed in cell therapy methods. Further, transplanted cells involve embryonic stem cells (ESCs), pluripotent stem cells (iPSCs), neural stem cells (NSCs), and mesenchymal stem cells (MSCs) are bifurcated mainly two groups viz. Allogeneic cell therapy and non-Allogeneic cell therapy.

At present, there are two types of cell therapies exist. The first type is cell therapy in mainstream medicine. This category includes human embryonic stem cell therapy, mesenchymal stem cell therapy, neural stem cell therapy, Autologous cell therapy, and hematopoietic stem cell therapy. The second category is in alternative medicine and perpetuates the practice of injecting animal materials in an effort to cure diseases. This practice, as per the American Cancer Society, is not supported by any medical proof of efficiency and can have fatal results.

The outbreak of the COVID-19 pandemic has affected many biopharmaceutical units, while many cellular therapy development organizations have observed a severe impact, which is due to the complexities in logistics and manufacturing models used in this sector. Moreover, considerable and constant investment is essential to allow effective commercial translation of cell-based therapeutics, an aspect that was negatively affected in 2020, further affected the overall market growth.

Therapy Type Outlook

Based on Therapy Type, the market is segmented into Autologous and Allogeneic. The Autologous therapies segment would show gradual growth due to the massive cost associated with Autologous transplants and comparatively less relapse rates. Though, development in cell banking and companies switch towards the creation of allogenic therapy products is boosting the cell therapy market.

Therapeutic Area Outlook

Based on Therapeutic Area, the market is segmented into Malignancies, Autoimmune Disorders, Musculoskeletal Disorders, Dermatology and Others. The Malignancies market dominated the Global Cell Therapy Market by Therapeutic Area 2019, growing at a CAGR of 25.2 % during the forecast period. The Autoimmune Disorders market is experiencing a CAGR of 27.6% during (2020 - 2026). Additionally, The Musculoskeletal Disorders market would showcase a CAGR of 27.2% during (2020 - 2026).

End User Outlook

Based on End User, the market is segmented into Academic & Research Institutes and Hospitals & Clinics. In 2019, the Academic & Research Institutes segment emerged as the leading segment of the market and held the highest revenue share. The stem cells are significantly being utilized for research projects, which as a result, has contributed to a massive revenue share for the Academic & Research Institutes segment. The segment would show a similar trend during the forecast period.

Cell Type Outlook

Based on Cell Type, the market is segmented into Stem Cell, Umbilical Cord-Derived, Adipose-Derived Stem Cell, Non-Stem Cell, Bone Marrow, Blood and Others. The Stem Cell market dominated the Global Cell Therapy Market by Cell Type 2019, and would continue to be a dominant market till 2026. The Umbilical Cord-Derived market is expected to witness a CAGR of 27.7% during (2020 - 2026).

Regional Outlook

Based on Regions, the market is segmented into North America, Europe, Asia Pacific, and Latin America, Middle East & Africa. In 2019, North America emerged as the leading region of the global cell therapy market by obtaining the highest revenue share. The larger share of the region is due to the existence of a considerable number of centers and institutes that are undergoing R&D activities to stem cell therapy. Among the top universities in the world, 5 are based in the U.S., including Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Harvard Stem Cell Institute, Harvard University, and Yale Stem Cell Center.

The major strategies followed by the market participants are Partnerships. Based on the Analysis presented in the Cardinal matrix; Fujifilm Holdings Corporation is the major forerunner in the Cell Therapy Market. Companies such as JCR Pharmaceuticals Co., Ltd., NuVasive, Inc., Medipost Co., Ltd., Vericel Corporation, and Avantor, Inc. are some of the key innovators in the market.

The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Fujifilm Holdings Corporation, Smith & Nephew PLC, Kolon TissueGene, Inc., JCR Pharmaceuticals Co., Ltd., Medipost Co., Ltd., Stemedica Cell Technologies, Inc., NuVasive, Inc., Avantor, Inc., Vericel Corporation, and Pharmicell Co., Ltd.

Recent strategies deployed in Cell Therapy Market

Partnerships, Collaborations, and Agreements:

Mar-2021: Fujifilm collaborated with Sana Biotechnology, a biotechnology company. Under this collaboration, Sana has permitted a non-exclusive right to utilize the Fujifilm Cellular Dynamics iPSC platform for the development of commercial cell therapies. Cell therapies as a treatment modality can boost, repair, or replace human biology that includes tissues, organs, and cells.

Nov-2020: Fujifilm came into partnership with Lonza Walkersville, a leading global GMP iPSC manufacturer. In this partnership, Fujifilm Cellular Dynamics permitted Lonza a non-exclusive right to utilize their patents related to iPSC generation, which include episomal vectors and reprogramming factors, for the clinical production and differentiation of iPSC lines for cell therapies.

Apr-2020: Fujifilm Diosynth Biotechnologies (FDB) entered into a partnership with OXGENE, an industry leader in the design and development of gene therapy technologies. The partnership enables FDB to provide gene therapy products to customers with an approximate 25% lead-time reduction.

Jun-2019: JCR Pharmaceuticals extended the partnership with Mesoblast Limited, an Australian-based regenerative medicine company. This expansion aimed to utilize mesenchymal stem cells (MSCs) for curing newborns who have insufficient blood supply and oxygen to the brain, this condition is termed neonatal hypoxic-ischemic encephalopathy (HIE).

Jan-019: Medipost signed a cooperation agreement with LG Chem, the largest Korean chemical company. In this agreement, both companies conducted research to discover a stem cell drug candidate for the next two years. Medipost would be responsible for making and delivering umbilical cord blood-derived mesenchymal stem cells and LG Chem has taken charge in choosing the genes, which cause disease and stem cell generation utilizing the genetic engineering techniques

Acquisition and Mergers:

Apr-2020: JCR Pharmaceuticals acquired ArmaGen, Inc., a privately-held US biopharmaceutical company. This acquisition is a testament to the companys robust commitment to bring advanced medicines to patients with mucopolysaccharidoses and other LSDs.

Mar-2019: Smith & Nephew came into agreement to acquire Osiris Therapeutics, a fast-growing company delivering regenerative medicine products. This acquisition will improve Smith & Nephews portfolio and help instantly boost their wound management business and also offer longer-term innovations in additional channels and indications.

Product Launches and Product Expansions:

Sep-2020: Smith & Nephew introduced the HEALICOIL KNOTLESS Suture Anchor. This launch expanded its revolutionary portfolio of Advanced Healing Solutions for rotator cuff repair. This line of a product consists of the innovative REGENETEN Bioinductive Implant and novel REGENESORB Material. These are developed to support a jump start in bone healing and formation.

Mar-2020: Avantor Performance Materials introduced a new recombinant Protein A affinity chromatography resin. It is a proven downstream purification step in producing mAbs. This new Avantor recombinant protein A resin helps in coping up with these challenges.

Jul-2019: NuVasive introduced its Pulse platform. This platform integrated various technologies into multiple spine surgery procedures, which include corrections, bone fusions, and more. The modular workflow product line encompasses surgical planning, patient-specific rod bending, and 2D and 3D imaging and also alignment, navigation, neurological monitoring, and radiation reduction at the time of operation.

Jan-2019: Fujifilm Cellular Dynamics unveiled iCell Microglia. It is the immune cells of the central nervous system helps in fundamental physiological and pathological processes. The iCell Microglia is different from human iPSCs is utilized in life science research to allow the study and development of therapies for degenerative neurological diseases like Alzheimers disease.

Geographical Expansions:

Jun-2020: Avantor expanded its Bridgewater, N.J. (USA) innovation center. This expansion improved the Companys R&D support for a personalized product and bioprocess development, and custom cell & gene therapy reagent production to support the customers therapeutic products, which are developed for improvements in customized medicines.

Dec-2019: Avantor expanded its global presence by opening an innovation and customer support center in Shanghai, China. This center supports biopharma research and technology development in the region. With this expansion, Avantor has nine innovation centers across the globe. The new Avantor laboratory helps the biopharmaceutical companies to escalate the development of life-changing treatments for patients in the region.

Jan-2019: Fujifilm Cellular Dynamics, a US subsidiary of Fujifilm Corporation expanded its geographical footprints by establishing a new cGMP-compliant production facility. This expansion aimed to improve its production of iPS cells for cell therapy.

Scope of the Study

Market Segments covered in the Report:

By Therapy Type

Autologous

Allogeneic

By Therapeutic Area

Malignancies

Autoimmune Disorders

Musculoskeletal Disorders

Dermatology

Others

By End User

Academic & Research Institutes

Hospitals & Clinics

By Cell Type

Stem Cell

Umbilical Cord-Derived

Adipose-Derived Stem Cell

Non-Stem Cell

Bone Marrow

Blood

Others

By Geography

North America

o US

o Canada

o Mexico

o Rest of North America

Europe

o Germany

o UK

o France

o Russia

o Spain

o Italy

o Rest of Europe

Asia Pacific

o China

o Japan

o India

o South Korea

o Singapore

o Malaysia

o Rest of Asia Pacific

LAMEA

o Brazil

o Argentina

o UAE

o Saudi Arabia

o South Africa

o Nigeria

o Rest of LAMEA

Companies Profiled

Fujifilm Holdings Corporation

Smith & Nephew PLC

Kolon TissueGene, Inc.

JCR Pharmaceuticals Co., Ltd.

Medipost Co., Ltd.

Stemedica Cell Technologies, Inc.

NuVasive, Inc.

Avantor, Inc.

Vericel Corporation

Pharmicell Co., Ltd.

Unique Offerings

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Global Cell Therapy Market By Therapy Type, By Therapeutic Area, By End User, By Cell Type, By Regional Outlook, Industry Analysis Report and...

Cell Biology

The Mesenchymal Stem Cells Market To Grow In Direct Proportion With Innovations KSU | The Sentinel Newspaper – KSU | The Sentinel Newspaper

The Mesenchymal Stem Cells Market report by Persistence Market Research is focusing on the fact that healthcare providers are into collection of socioeconomic information of the patients, so that tracking at any point of time is possible. This on-the-go monitoring is amongst the ongoing trends in the healthcare industry.

How about looking through the sample of Mesenchymal Stem Cells market report?https://www.persistencemarketresearch.com/samples/3309

North America dominates the global market for mesenchymal stem cell due to large number of aging population and increasing incidence of cancers. Asia is expected to show high growth rates in the next five years in the global mesenchymal stem cell market. China and India are expected to be the fastest growing mesenchymal stem cell markets in Asia-Pacific region. Some of the key driving forces for mesenchymal stem cell market in emerging countries are large pool of patients and rising government funding and support.

Want a sneak peek into the Mesenchymal Stem Cells market? Access the Table of Content of Mesenchymal Stem Cells market report!https://www.persistencemarketresearch.com/toc/3309

In recent times there is increased use of mesenchymal stem cell due to increasing aging population. Rising incidence of chronic diseases, regulatory and government support and increasing investment in stem cell biology are some of the key factors driving the growth for the global mesenchymal stem cell market. In addition, increasing use of mesenchymal stem cell as a substitute to knee replacement surgeries and other operative procedures is also fuelling the growth of the global mesenchymal stem cell market. However, lack of therapeutic advancement related to vitro properties of stem cell is the major factor restraining the growth for the global mesenchymal stem cell market.

Planning to enter the arena of Mesenchymal Stem Cells market? Prebook our Mesenchymal Stem Cells market report!https://www.persistencemarketresearch.com/checkout/3309

Numerous ethical, political and religious controversies on mesenchymal stem cell could lead a challenge for the global mesenchymal stem cell market. Some of the trends for the global mesenchymal stem cell market are increasing collaborations and partnerships and rising innovation of mesenchymal stem cell products. Some of the major companies operating in the global mesenchymal stem cell market are EMD Millipore Corporation, Cell Applications, Inc., Cyagen Biosciences, Inc., Genlantis, Inc., Advanced Cell Technology Incorporated, Stemcell Technologies Inc., Celprogen, Inc., Stemedica Cell Technologies, Aastrom Biosciences and ScienCell Research Laboratories.

Explore Extensive Coverage of Persistence Market ResearchsHealthcare Industry

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The Mesenchymal Stem Cells Market To Grow In Direct Proportion With Innovations KSU | The Sentinel Newspaper - KSU | The Sentinel Newspaper

Cell Biology

Columbia researchers uncover COVID-19’s impact on brain | – University Business

The team's findings suggest inflammation may trigger neurologic damage but the virus' long-term impact on memory and mood is still unknown.

Higher education institutions have played a critical role in assisting on the front lines and behind the scenes during the COVID-19 pandemic. From vaccine development to clinic rollouts to research around the novel coronavirus, scientific and medical developments have paved the way for strategic decisions to be made on campuses, in communities and across the globe.

Some of those breakthroughs not only have helped in the moment but also will provide a working base for further discoveries and planning, around this crisis and others in the future.

Late last week, in the publication Brain, a neurology team at Columbia Universitys Vagelos College of Physicians and Surgeons revealed major findings in studies done at Irving Medical Center/New York Presbyterian Hospital. In more than three dozen patients who had contracted the virus and died, all of them had sustained significant neurologic effects from SARS-COV-2.

We observed many pathological changes in these brains, which could explain why severely ill patients experience confusion and delirium and other serious neurological effects, and why those with mild cases may experience brain fog for weeks and months, said Dr. James Goldman, professor of pathology and cell biology in psychiatry, who led the study along with professors Dr. Peter Canoll and Dr. Kiran Thakur.

They also made another important discovery.

Theres been considerable debate about whether this virus infects the brain, but we were unable to find any signs of virus inside brain cells of more than 40 COVID-19 patients, Goldman said.

Inside the report

The study was conducted on 41 patients age 38 to 97 who had been hospitalized before losing their battles to COVID-19. Some died soon after being admitted, while others passed away after months of fighting the virus. Researchers noted that about half of the patients had been intubated. In addition to the damage done to the brain, they all experience lung damage, one of the hallmarks of COVID-19.

The first thing we noticed was a lot of areas with damage from a lack of oxygen, Goldman said. They all had severe lung disease, so its not surprising that theres hypoxic damage in the brain.

Researchers noted that blood clots likely caused the hypoxic damage. In addition, Canoll said microglia, or dormant immune cells in the brain that can be triggered by diseases, were seen often in patents. It is likely the inflammation throughout the body caused those cells to be activated, so even without directly infecting brain cells, COVID-19 can cause damage to the brain, he said.

One concern is the potential long-term effects of those who have gotten the virus and the length of time their bodies may have been fighting COVID-19. Since they were found mainly in the lower brain stem area, could the movement of microglia affect memory and mood?

We know the microglia activity will lead to loss of neurons, and that loss is permanent, Goldman says. Is there enough loss of neurons (in the hippocampus) to cause memory problems? Or in other parts of the brain that help direct our attention? Its possible, but we really dont know at this point.

So, Columbia researchers will continue to study patterns. They are currently looking at those who recovered from COVID-19 but then passed away as well as patients who had pre-existing respiratory issues to determine how much of COVID-19 brain pathology is a result of the severe lung disease.

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Columbia researchers uncover COVID-19's impact on brain | - University Business