Nasal oxidative stress mediating the effects of colder temperature exposure on pediatric asthma symptoms | Pediatric … – Nature.com

April 15, 2024 medical

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Nasal oxidative stress mediating the effects of colder temperature exposure on pediatric asthma symptoms | Pediatric ... - Nature.com

Pediatrics

Week in review: A new dermatology case study, and a new treatment for severe asthma – Contemporary Pediatrics

April 15, 2024 medical

Thank you for visiting the Contemporary Pediatrics website. Take a look at some of our top stories from last week (Monday, April 8, to Friday, April 12, 2024), and click on each link to read and watch anything you may have missed.

1.) Young woman with tick bites presents with erythematous papules, headaches, and fatigue

A young woman with no significant past medical history returns from hiking with several white-spotted ticks and experiences erythematous papules, rashes, headaches, and fatigue. Whats the diagnosis?

Click here for the full case, differential diagnosis, and case diagnosis.

2.) FDA approves benralizumab for children aged 6 to 11 years with severe asthma

The FDA approval of benralizumab for patients ages 6 to 11 with asthma follows the conclusions of the phase 3 TATE study. Click here for full FDA approval details.

3.) FDA approves dolutegravir/lamivudine to treat HIV infection in adolescents

The indication is approved for those with no antiretroviral (ARV) treatment history or to replace current ARV regimen in those, "are virologically suppressed (HIV-1 RNA less than 50 copies/mL) on a stable ARV regimen with no history of treatment failure and no known substitutions associated with resistance to the individual components of [dolutegravir/lamivudine]," ViiV stated.

Click here for full approval details.

4.) Does vitamin C among pregnant smokers improve airway function trajectory in offspring?

"Our findings provide evidence for a direct association between maternal smoking during pregnancy and wheeze occurrence," wrote the authors.

Click here for the full article.

5.) Does acetaminophen intake during pregnancy influence childrens risk of neurodevelopmental disorders?

A recently published study in JAMA sought to determine if there is a link between acetaminophen use during pregnancy and childrens risk of developing autism, ADHD, or intellectual disabilities.

Click here for the full article.

Week in review: A new dermatology case study, and a new treatment for severe asthma - Contemporary Pediatrics

Cell Biology

Close Encounters of Skin and Nerve Cells – The Scientist

April 15, 2024 medical

A tickly itch, a painful scratch, or the feeling of a refreshing breezethe skin is teaming with nerve endings that drive these sensations. Scientists are getting into the epidermis to explore how skin and nerve cells interact.

Peering through a microscope at skin tissue, researchers struggle to tease apart the intricate connections occurring inside tight bundles of skin and nerve cells.1 However, recent advances in microscopy have helped solve this intractable problem. Published in eLife, Nurcan eyler, a neurologist at the University of Wrzburg, and her colleagues used emerging imaging techniques to discover that nerve fibers not only weave around skin cells but also pass through them.2 The findings intimate a route by which skin cells transmit sensory signals to the nervous system.

The skin is basically the window to the outside, said Kathryn Albers, a neuroscientist at the University of Pittsburgh who was not involved with the work but reviewed the study. Despite this, scientists have long overlooked the role skin cells play in nerve stimulation. eyler hopes that their findings will open new doors for research. I think were at the beginning of changing minds, she said.

A chance discovery made by Christoph Erbacher, then a doctoral student in eylers laboratory, set the project in motion. He had started working on his PhD thesis on a completely different topic, eyler said. However, when Erbacher looked at skin tissue under the microscope, he noticed that nerve fibers did not just grow around skin cells but, to the whole teams surprise, tunneled straight through them. Eager to inspect these interactions in closer detail, the team turned to state-of-the-art imaging strategies that zoom deep inside cells to bring fine structures into view.

Continue reading below...

Structured illumination microscopy, a technique that takes multiple snapshots of a sample under different patterns of light, allowed eyler and her team to acquire super-resolution images of skin tissue. With the help of fluorescent antibodies that bind specifically to nerves, they located nerve tunnels passing through skin cells. Then, to capture the cells interior architecture, they used electron microscopy.3 The combination of the two strategies, called correlative light and electron microscopy (CLEM), allowed the researchers to see which architectural details corresponded to the fluorescently-stained nerve fibers.4

A single snapshot of a cell can only reveal so much. By imaging several layers in a sliver of tissue,the researchers could determine whether a nerve fiber tunneled through a cell rather than over or under it. They scrolled through cross-sections of the cell, starting at the base and moving up. All of a sudden, the fiber appears, and you can very clearly see youre in the middle of the cell, eyler said.

Examining the close-up architectural details afforded by CLEM, the researchers noticed that the tunneling fiber, as thin as one micrometer in width, did not puncture the skin cell membrane and poke into the cytoplasm, like a needle piercing through flesh. Rather, the membrane ensheathes the fiber, like rubber insulation around electrical wires.

Researchers captured nerve fibers (green) tunnelling through skin cells (magenta) using cutting-edge microscopy. Scale bar = 5m

Christoph Erbacher

With a detailed view of skin-nerve connections, the researchers explored whether proteins responsible for transmitting signals accumulate on these tunneling fibers. Using a flurry of fluorescent antibodies to search for such a protein, they found that connexin 43, a protein that normally participates in communication between skin cells, decorated the nerve fibers.5 Connexin 43 aggregates in a ring to generate pores in the cell membrane that allow entry of chemical signals such as calcium ions.6 eylers team also found that the calcium ion level spiked inside the cells when the nerve fibers tunneled through, which suggested that the two cell types communicate.

What started out as a chance observation may have implications for healthcare down the road. This skin-nerve cell link could inform research on nervous system disorders that affect the skin. For example, small fiber neuropathy causes a chronic, persistent burning pain on the skin, and eyler hopes that future studies will reveal whether nerve tunnels play a role in the condition.7 Currently, the few treatment options that exist target the nerves directly, but researchers may one day develop therapies that target the skin cells instead.

Before that can happen, scientists must first scratch deeper to unravel the biology of these nerve tunnels. Albers would like to know how these tunnels entwine with skin cells as they migrate from the base layer to the skin surface. She also wondered if nerve fibers tunnel into other cell types found in skin tissue, such as immune cells, and what that crosstalk between cell types might achieve.

No one tissue exists alone; everything communicates at some level, said Albers.

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Close Encounters of Skin and Nerve Cells - The Scientist

Cell Biology

Impact of aldehydes on DNA damage and aging – EurekAlert

April 15, 2024 medical

image:

Histones are crosslinked with DNA (histone-DPC) following formaldehyde exposure, leading to the malfunction of cellular processes such as transcription.

Credit: Reiko Matsushita

A team of researchers at Nagoya University in Japan has discovered that aldehydes are metabolic byproducts associated with premature aging. Published in Nature Cell Biology, their findings reveal insights into premature aging diseases and potential strategies to combat aging in healthy individuals such as controlling exposure to aldehyde-inducing substances including alcohol, pollution, and smoke.

A person's health can be harmed by aldehydes. However, the groups findings suggest these detrimental effects also include aging. The team who made this discovery included Yasuyoshi Oka, Yuka Nakazawa, Mayuko Shimada, and Tomoo Ogi of Nagoya University.

DNA damage is linked with aging phenotypes, said Oka. However, for the first time, we propose a relationship between aldehyde-derived DNA damage and premature aging.

The researchers hypothesized that there might be a link between aldehydes and aging since individuals with premature aging disorders, like AMeD syndrome, exhibit inadequate activity of enzymes, like ALDH2, that break down aldehydes.

For healthy individuals, ALDH2 is also important in our response to alcohol. When a person drinks wine or beer, the liver metabolizes the alcohol into aldehydes so it can be eliminated from the body. The activity of ALDH2 is important for converting the aldehydes into a non-toxic substance.

Aldehydes are harmful because they are highly reactive with DNA and proteins. In the body, they form DNA-protein crosslinks (DPCs) that block important enzymes in typical cell proliferation and maintenance processes, causing these processes to malfunction and the patient to age.

Focusing on DPCs caused by aldehyde, the scientists used a method called DPC-seq to investigate the link between aldehyde accumulation and DNA damage in premature-aging disease patients. In a series of experiments, the researchers discovered that the TCR complex, VCP/p97, and the proteasome are involved in the removal of formaldehyde-induced DPCs in actively transcribed regions. This was confirmed by a mouse model lacking both aldehyde clearance processes and the TCR pathway that showed worse AMeD syndrome symptoms.

These processes are important because they are related to the clearance of aldehydes. It suggests an association between premature aging diseases and aldehyde accumulation.

Professor Ogi is hopeful about the implications of their findings, stating: "By elucidating the mechanism by which DNA damage heals quickly, we have revealed part of the cause of genetic premature aging.

Our research opens up new avenues for understanding the underlying mechanisms of premature aging diseases and offers potential targets for therapeutic intervention, Oka said. By elucidating the role of aldehydes in DNA damage and aging, we are paving the way for future studies aimed at developing novel treatments and interventions."

He continued: The development of therapeutic drugs has not progressed because we have not fully understood the causes of AMeD syndrome and Cockayne syndrome. This study suggests that the patient's pathological condition is related to DPC derived from aldehydes generated within cells. These results are expected to help in the search for compounds that remove aldehydes, thus aiding in the formulation of therapeutic drug candidates.

This research has implications that extend beyond genetic diseases, as their findings suggest that aldehyde-induced DNA damage may play a role in the aging process in healthy individuals too. By pinpointing aldehydes as substances that contribute to aging, this study sheds light on the intricate connection between environmental factors and cellular aging. This may have significant implications for human health and lifespan.

Nature Cell Biology

Endogenous aldehyde-induced DNA-protein crosslinks are resolved by transcription-coupled repair

10-Apr-2024

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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Impact of aldehydes on DNA damage and aging - EurekAlert

Cell Biology

OrthoID: Decoding Cellular Conversations with Cutting-Edge Technology – yTech

April 15, 2024 medical

Summary: OrthoID is a novel strategy developed by an interdisciplinary research team to enhance our understanding of organelle communication within cells. It surmounts issues inherent in traditional methodologies and brings forth new levels of clarity to the study of cellular processes related to health and disease.

Within the realm of cellular biology, the nuanced dialogue between organelles like mitochondria and the endoplasmic reticulum (ER) is critical for maintaining cell health. Disruptions in this dialogue have implications in a host of diseases, making it imperative to understand it in detail. Innovatively engineered, OrthoID has been meticulously crafted to offer us deeper insights into organelle communication.

OrthoID differentiates itself from previous methods by using a synthetic binding pair in conjunction with the classic streptavidin-biotin system. This dual binding scheme unveils previously hidden facets of organelle interaction, enabling researchers to capture a broader array of mediator proteins. The technique has already borne fruit, uncovering novel proteins like LRC59 and illuminating their specific functions within the ER-mitochondria contact sites.

The flexibility of OrthoID is one of its many innovations, allowing scientists to customize their approach to studying various organelle interactions. This adaptability was emphasized by Professor Kimoon Kim of POSTECH, who noted the technologys modular nature that could extend beyond ER-mitochondrial studies. Meanwhile, Professor Kyeng Min Park from Daegu Catholic University School of Medicine highlighted its role as a versatile research instrument with promising applications in both understanding and treating diseases.

Overall, OrthoID is forging a path towards a transformative comprehension of cell mechanics, directly impacting future biomedical research and therapy development. The techniques unique perspective on the protein players in organelle communication is reshaping how scientists approach the intricate cellular landscape, bringing us one step closer to unraveling the mysteries of cellular life.

Industry Overview

The biotechnology and pharmaceutical industry is increasingly focusing on cellular biology as a fundamental aspect of understanding disease and developing new therapies. Organelle communication within cells is particularly pertinent to a range of conditions, including neurodegenerative diseases, cancer, and diabetes. The market for cell biology reagents and technologies is on a persistent growth trajectory, fueled by expanding research in cell and molecular biology. Market forecasts suggest that the global market for these technologies, driven by the need for more precise diagnostic tools and effective therapeutic options, is expected to experience significant growth over the next several years.

Market Forecasts

According to industry forecasts, one can expect the market for cell biology reagents and instruments to reach billions of dollars by the end of the decade. North America and Europe are leading this growth, with Asia-Pacific regions showing the highest growth rates due to increasing investments in biotechnology and healthcare infrastructure.

Industry Issues

Despite the anticipated growth, the industry faces several issues. High costs and technical complexities of advanced technologies can pose barriers to entry for smaller research institutions. Intellectual property rights, stringent regulatory frameworks, and ethical considerations surrounding biomedical research are additional challenges that impact industry dynamics. Furthermore, the reproducibility crisis in biological sciences, referring to the difficulty in replicating and validating research findings, underscores the need for reliable technologies like OrthoID.

OrthoIDs Role in the Industry

The development of OrthoID signifies a substantial advancement in the field. It provides a more discerning and versatile tool for the dissection of organelle communication pathways. As diseases often affect or are affected by cellular processes, mastering the intricacies of cell function with technologies like OrthoID can lead to the discovery of novel therapeutic targets. In the near future, this could facilitate the development of treatments that are more targeted and effective.

With continued research and development, medical scientists and researchers can leverage OrthoIDs detailed insights into organelle communication to overcome diseases that have remained enigmatic thus far. In the ever-evolving landscape of biotechnology, products such as OrthoID that provide novel means of understanding biological systems are invaluable.

For more information on the latest advancements and trends within the biotechnology industry, consider visiting reputable sources like the Nature Publishing Group or the World Health Organization (WHO), which can provide up-to-date news and comprehensive reports.

Micha Rogucki is a pioneering figure in the field of renewable energy, particularly known for his work on solar power innovations. His research and development efforts have significantly advanced solar panel efficiency and sustainability. Roguckis commitment to green energy solutions is also evident in his advocacy for integrating renewable sources into national power grids. His groundbreaking work not only contributes to the scientific community but also plays a crucial role in promoting environmental sustainability and energy independence. Roguckis influence extends beyond academia, impacting industry practices and public policy regarding renewable energy.

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OrthoID: Decoding Cellular Conversations with Cutting-Edge Technology - yTech

Genetics

Introgression and disruption of migration routes have shaped the genetic integrity of wildebeest populations – Nature.com

April 15, 2024 medical

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Genetics

A pan-genome of 69 Arabidopsis thaliana accessions reveals a conserved genome structure throughout the global … – Nature.com

April 15, 2024 medical

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Genetics

Is Left-Handedness Tied to Your Genetics? Possibly, New Study Suggests – Technology Networks

April 15, 2024 medical

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Its a question that has spurred many hypotheses over the years. The general consensus in modern science is that right- or left-brain hemisphere dominance dictates our handedness.

Studies of human fetuses have shown that right-lateralized predominance of arm movements can occur as early as 10 weeks into gestation in right-handed individuals. The fact that this right- or left-sided preference is apparent so early on in human development suggests that genetically regulated mechanisms could be at play.

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To further probe how genetics might contribute to handedness, scientists at the Max Planck Institute (MPI) for Psycholinguistics turned to the UK Biobank, a large-scale biomedical database that contains genetic data from thousands of individuals in the UK. Their research is published in Nature Communications.

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Led by Dr. Clyde Francks, senior investigator in the language and genetics department at MPI, the scientists analyzed and compared exome data from 313,271 right-handed people and 38,043 left-handed people.

The collection of exons protein-coding DNA sequences in the genome is known as the exome.

A specific genetic variant was found to be much more common in left-handed people than right.

The beta-tubulin gene TUBB4B shows exome-wide significant association, with a rate of rare coding variants 2.7 times higher in left-handers than right-handers, the authors said.

TUBB genes encode proteins found in microtubules, which help to control the structure and movement of cells. Microtubules are prominent parts of the cytoskeleton the framework of protein filaments internal to cells that contributes to a wide range of processes including cellular growth, division, migration, shape and axis formation, axon outgrowth and intracellular transport, the researchers explained.

How microtubules affect variation in human handedness is not currently known. Previous research suggests a role in cellular chirality during brain development, which might impact the formation of the brains leftright axis.

Brain magnetic resonance imaging (MRI) data was only available for 13 of the UK Biobank TUBB4B variant carriers (left- and right-handers together), which is too small a sample for reliable association mapping with respect to brain structural or functional asymmetries, Francks and team said. Neither of the left-handed frameshift variant carriers had MRI data.

Some studies have identified TUBB genes as the underlying cause of incredibly rare neurological disorders. Intriguingly, mutations in TUBB2B can cause asymmetrical polymicrogyria (many and small folds) of the cerebral cortex, the researchers said. Mutations in TUBB3 can cause asymmetrical cortical dysplasia and unilateral hypohidrosis (reduced sweating on one side of the body, thought to be linked to disrupted function of the cortex, brain stem and spine). It may therefore be informative to collect brain MRI data from TUBB4B variant carriers in future studies, they add.

Reference: Schijven D, Soheili-Nezhad S, Fisher SE, Francks C. Exome-wide analysis implicates rare protein-altering variants in human handedness. Nat Comms. 2024;15(1):2632. doi: 10.1038/s41467-024-46277-w

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Is Left-Handedness Tied to Your Genetics? Possibly, New Study Suggests - Technology Networks

Genetics

Katie Gallagher MS ’15, CGC Named Director of the Joan H. Marks Graduate Program in Human Genetics at Sarah … – Sarah Lawrence College

April 15, 2024 medical

The Joan H. Marks Graduate Program in Human Genetics at Sarah Lawrence Collegethe oldest and largest graduate program of its kindhas named alumna Katie Gallagher, CGC as its new director.

Katie intimately understands the missions and strengths of both the program and the College and the intricate web of relationships that help the program thrive, said Dean of Graduate & Professional Studies Kim Ferguson. She has demonstrated a relentless drive to make a meaningful impact on the world of genetics, and I am excited to see her bring that drive to her new role as director.

A 2015 graduate of the program, Gallagher has served in a number of roles, including clinical supervisor, course instructor, and, most recently, assistant director, since joining the Human Genetics program staff in 2016. An accomplished certified genetic counselor and educator with proven success in settings of innovation and rapid evolution, Gallagher has experience in clinical pediatric genetics, laboratory genetics services, and genomics research.

I take pride in shaping the future of genetic counselors and recognize the colossal reputation our program has, said Gallagher. I see the program as forward-thinking and a beacon of innovation, capable of guiding the profession towards positive change, and Im excited to be part of that work.

One particular area of focus as Gallagher takes the reins is a commitment to promoting diversity, equity, inclusion, and belonging within the program and in the genetic counseling profession. I fervently believe that diversity is not just an aspiration but an essential driver of progress in our field, she said.

Gallagher succeeds Claire Davis, EdD, MS, CGC, who has been the director of the Human Genetics program since 2018. Davis is moving on to a new role as co-director of the Master of Science in Genome Health Analysis program, a partnership between NYU and Sarah Lawrence College. She is also the Director of Curriculum for Sarah Lawrences Institute for Genomics Education, Workforce, and Leadership and will remain on the Human Genetics program faculty.

Gallagher will begin her tenure as director on May 1, 2024.

Founded in 1926, Sarah Lawrence is a prestigious, coeducational liberal arts college that consistently ranks among the leading liberal arts colleges in the country. Sarah Lawrence is known for its pioneering approach to education, rich history of impassioned intellectual and civic engagement, and vibrant, successful alumni. In close proximity to the unparalleled offerings of New York City, the historic campus is home to an intellectually curious and diverse community.

Genetics

ACMG Foundation for Genetic and Genomic Medicine Elects Four Highly Accomplished Medical Genetics … – PR Newswire

April 15, 2024 medical

BETHESDA, Md., April 11, 2024 /PRNewswire/ --The ACMG Foundation for Genetic and Genomic Medicine (ACMGF) announced today that Marilyn C. Jones, MD, FACMG; Harry Ostrer, MD, FACMG; Lisa G. Shaffer, PhD, FACMG and Katie Johansen Taber, PhD were elected to the Board of Directors of the ACMGF. The ACMG Foundation is a national nonprofit foundation dedicated to facilitating the integration of genetics and genomics into medical practice. The board members are active participants, serving as advocates for the ACMG Foundation and for advancing its policies and programs.

ACMG Foundation President Nancy J. Mendelsohn, MD, FACMG said, "We are pleased to welcome these four new members to the ACMG Foundation Board of Directors. Individually and combined they bring a new perspective along with their individual deep expertise. We are grateful for their enthusiasm and willingness to serve our genetics and genomics community."

Marilyn C. Jones, MD, FACMG

A Past President of the ACMG (2007-2009), Dr. Marilyn C. Jones is the Clinical Services Chief of the Genetics and Dysmorphology Division at Rady Children's Hospital in San Diego and a Distinguished Professor of Clinical Pediatrics at the UC San Diego School of Medicine.She has served as the Medical Director of the Helen Bernardy Center for Medically Fragile Children for more than 40 years. With expertise in providing detailed patient phenotyping to aid gene discovery, Dr. Jones's career has focused on identifying underlying causation among patients with cleft and craniofacial disorders. In 2020 she received the David Bixler Distinguished Scientist in Craniofacial Research Award from the Society for Craniofacial Genetics and Developmental Biology, as well as the David W. Smith Award for Excellence in Genetics and Birth Defects Education from the American Academy of Pediatrics.

"I am honored for the opportunity to serve the ACMG again through participation in the Foundation Board of Directors. The Foundation provides many of the resources that help the College move forward its agenda to help both the public and its members," said Dr. Jones.

Harry Ostrer, MD, FACMG

Dr. Harry Ostrer is Professor of Pathology and Pediatrics at Albert Einstein College of Medicine. From 1990-2011, he was the Director of the Human Genetics Program at New York University Langone Medical Center. His academic focus is in studying the genetic basis for common and rare disorders and developing new functional genomic technologies. Dr. Ostrer is also a long-time investigator of the genetics of the Jewish people and Hispanic and Latino people. In 2007, he organized the Jewish HapMap Project, an international effort to understand origins, migration and disease predispositions by mapping and sequencing the genomes of Jewish people. At his start-up company, Morgan and Mendel Genomics, Dr. Ostrer advises about translating the findings of novel functional genomic discoveries into tests that can be used to identify people's risks for having cancer or for predicting cancer's response to therapy.

"My professional career has been entwined with creating opportunities for others in medical genetics by training them, sometimes through training programs that I created. But part of passing the mantle of achieving 'better health through genetics' for everyone is to support even larger and scalable opportunities," said Dr. Ostrer. "I am delighted to have the means to do so by joining old and new friends on the Board of Directors of the American College of Medical Genetics Foundation, whose philanthropic mission is to fund new programs and research."

Lisa G. Shaffer, PhD, FACMG

Dr. Lisa G. Shaffer is founder and the former CEO of Genetic Veterinary Sciences, Inc. (DBA Paw Print Genetics), a canine, feline and avian genetic testing company serving breeders, veterinarians and owners. The company was acquired in 2021. Prior to that enterprise, she was co-founder, President and CEO of Signature Genomic Laboratories, the first diagnostic laboratory to offer clinical microarray testing for children with developmental disabilities. The recipient of numerous accolades for her entrepreneurship and business savvy, Dr. Shaffer was previously a tenured Professor of Molecular and Human Genetics at Baylor College of Medicine (1991-2002) and in the School of Molecular Biosciences at Washington State University (2002-2008). Dr. Shaffer has authored more than 340 peer-reviewed medical papers and four books.

"I am very excited to be rejoiningthe ACMG Foundation Board of Directors and look forward to supporting the mission of the ACMG and helping to raise awareness of medical genetics and promote its achievements. Medical genetics touches every aspect of human health, and this is an exciting time to be a part of the Foundation," said Dr. Shaffer.

Katie Johansen Taber, PhD

As the Vice President of Clinical Product Research & Partnerships at Myriad Genetics, Dr. Katie Johansen Taber's focus is on developing evidence and advancing initiatives to improve access to genetic testing in the areas of women's health, oncology and mental health.She leads a team responsible for clinical evidence strategy, real-world evidence development, clinical trial conduct and scientific publications. Prior to her current position, Dr. Johansen Taber was Senior Director of Clinical Development at the company's Women's Health business unit. Before joining Myriad Genetics, she served at the American Medical Association (2006-2017), where her work centered on educating healthcare professionals about the clinical implementation of genomics and precision medicine, and on identifying and managing precision medicine policy issues. Dr. Johansen Taber has held numerous positions on advisory committees and boards, including a current appointment on the National Academy of Sciences, Engineering and Medicine Roundtable on Genomics and Precision Health.

"I'm thrilled to be elected to the ACMG Foundation Board of Directors and I look forward to working together to improve access to genetic testing," said Dr. Johansen Taber. "The Foundation's focus on evidence-based guidelines development, education and advocacy are important initiatives in realizing the ability to provide genetics-informed care to all patients who need it."

ACMGF Also Announces New Board Position and Thanks Outgoing Board Members

In addition,Brynn Levy, MSc. (Med), PhD, FACMG, who joined the ACMG Foundation Board of Directors in 2019, was named to the newly created officer position of President-Elect.

The ACMG Foundation also thanked the following board members who recently completed their terms of service: Nasha Fitter, MBA; Evan Jones, MBA and, in particular, David A.H. Whiteman, MD, FAAP, FACMG, who joined the Foundation Board of Directors in 2014 and served admirably as its Vice President since 2017.

A complete roster of the ACMG Foundation Board can be found at http://www.acmgfoundation.org.

About the ACMG Foundation for Genetic and Genomic Medicine

The ACMG Foundation for Genetic and Genomic Medicine, a 501(c)(3) nonprofit organization, is a community of supporters and contributors who understand the importance of medical genetics and genomics in healthcare. Established in 1992, the ACMG Foundation supports the American College of Medical Genetics and Genomics (ACMG) mission to "translate genes into health." Through its work, the ACMG Foundation fosters charitable giving, promotes training opportunities to attract future medical geneticists and genetic counselors to the field, shares information about medical genetics and genomics, and sponsors important research. To learn more and support the ACMG Foundation mission to create "Better Health through Genetics" visit acmgfoundation.org.

Contact: Kathy Moran, MBA [emailprotected]

SOURCE ACMG Foundation for Genetic and Genomic Medicine

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ACMG Foundation for Genetic and Genomic Medicine Elects Four Highly Accomplished Medical Genetics ... - PR Newswire