Grey’s plays out the Trump worldview against a hospital backdrop – A.V. Club

Feb 10, 2017 6:00 AM

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Because The A.V. Club knows that TV shows keep going even if were not writing at length about them, were experimenting with discussion posts. For certain shows, one of our TV writers will publish some brief thoughts about the latest episode, and open the comments for readers to share theirs.

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Beyonc’s Lemonade Director Enlists Grey’s Anatomy’s Jesse Williams for His Latest Fashion Spectacle – Vanity Fair

Left, Khalil Joseph, March 2015; Right, Humberto Leon and Jesse Williams at the Music is My Mistress premiere party on February 9, 2017.

Left, by Owen Kolasinksi/BFA/Rex/Shutterstock; Right, courtesy of Donato Sardella/Getty Images/Kenzo.

Kahlil Joseph, the writer-director who co-helmed Beyoncs epic visual-concept album, Lemonade, has debuted his latest work of arta film for the French luxury brand Kenzo.

The auteur has partnered with Kenzos creative directors, Carol Lim and Humberto Leon, to make an original short film, Music Is My Mistress, that features the labels chicest looks from their spring/summer 2017 collection. Greys Anatomy star Jesse Williams stars as a lost music manager searching for an African luminary played by newly minted Golden Globe winner Tracee Ellis Ross (from TVs Black-ish).

The film is about blackness, Joseph told Vanity Fair at a special screening party held at L.A.s Underground Museum on Thursday night. He went on to explain that his objective was to portray African-Americans realistically on-screen in the way they move, talk, and interact with people.

The theme of blackness is also prevalent in Lemonade. Since working with Beyonc on her visual spectacle, the Grammy-nominated director says his life is relatively the same. Hes just thankful that the opportunity to work with his close pal finally came to fruition.

I have known Beyonc through friends for a while, and we had talked about working together on stuff in the past, said Joseph, who has also worked with Kendrick Lamar and film director Terrence Malick. Lemonade was the one that just made sense to work together. It was an important and personal story.

For Williams, who is an outspoken human-rights activist, creating a piece of art like Kenzos short film is more important than ever now that uncertaintyand fearis gripping the nation in the Trump era.

The art community means a tremendous amount in times of bliss and in times of peril. The world is in a very contentious moment right now, and its all the more important now for people to be able to create daring, inclusive, forward-leaning material that is challenging for the status quo, Williams told Vanity Fair. Artists shake shit up and they drive the conversation and establish a new stake in the ground. Its so important to keep on doing this.

But some critics believe celebrities and artists should keep their political opinions to themselves, saying they live in a privileged world and have no real understanding of the issues faced by others. Williams strongly objects to that idea.

Actors should talk and to continue to speak up about politics. Acting is a job. A career. If Im a plumber, can I only fix pipes? If Im a teacher, can I only teach? If thats a rule, its fucking bizarre and ridiculous, he explained. I cant care about being a member of the electorate and what happens in the legislative office? Its asinine. I have been a politically active, social-justice activist my whole life, and I happened to have started acting. I think people should do what they want to do.

Williams, who made headlines in June for a speech he gave at the B.E.T. Awards, vows to fight relentlessly against social injustice and to continue to provide entertainment through his acting career.

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Beyonc's Lemonade Director Enlists Grey's Anatomy's Jesse Williams for His Latest Fashion Spectacle - Vanity Fair

The anatomy of a banked-in 3-pointer – Lynchburg News and Advance

A.C. Reid is making a habit of banking in 3-point shots with the outcome of Libertys most recent games hanging in the balance.

He banked in a 3 from the left wing as time expired to lift the Flames to a dramatic victory over Radford one week ago at the Vines Center. The junior guard needed the backboard again, this time Thursday night against Gardner-Webb at Paul Porter Arena, to force a second overtime and cap the Flames remarkable comeback win against the Runnin Bulldogs.

What has led to Reid having the confidence to make those shots? The 6-foot-5 guard has never lacked the confidence to take shots since he arrived on campus, but he has become better at shooting off the dribble and with bigger players contesting his shot.

Those two aspects have greatly assisted Reid in getting the shots up quickly and accurately, even though hed prefer his shots to swish through the net instead of banking in off the backboard.

I think its actually kind of difficult to go from that far and try to bank a shot in, Reid said. Ive been blessed these past two games to hit both of those shots.

Reids transformation has steadily taken place this season. His first two seasons were highlighted by his ability to make multiple 3-pointers in a row, but also to be easily pushed off the 3-point line and not get a shot off if he didnt get a clean look to catch and shoot.

Former Liberty basketball player Alex McLean joined the coaching staff as a graduate assistant this season and the players have credited his work with them on improving all facets on the offensive end.

He has particularly worked with Reid and fellow junior guard Ryan Kemrite during drills about two hours before each game on dribbling and shooting, catching and shooting and finishing their shots through contact.

Once that is completed, McLean and Reid begin shooting from midcourt in a challenge to see who can make the most attempts.

Alex does a great job with us and even the coaching staff does a great job with us of just getting a lot of game shots, Reid said. Coach [Ritchie] McKay said it in film the other day, If A.C.s going to be taking those deep shots, then yall need to be practicing that with him in his individual work. I think its just getting those constant reps that will give me the confidence just to take those deep shots during the game.

Reid missed his first five 3-point attempts against Radford before connecting on the banked-in attempt. He caught the inbounds pass from Georgie Pacheco-Ortiz, dribbled to his left and shot from about 24 feet over the outstretched arms of Radford 6-foot-8 center Randy Phillips.

Reid made his first two 3-pointers against Gardner-Webb, but missed five straight long-range attempts before he connected from 30 feet with 1.5 seconds remaining in the first overtime.

Reids shot came in a disjointed sequence as the Flames quickly attempted to get an open look. Pacheco-Ortiz handed the ball off to Reid, who took one dribble in and unleashed his shot from the right wing as GWU 6-foot-6 forward DJ Laster reached out his arm to contest.

I think when youre a confident shooter, youre a confident shooter and he is that, McKay said. He walks on the floor thinking hes going to make the shot. The fact that hes hit a couple of banks probably is attributed more to his nature and his fearlessness than his confidence. He thinks hes going to have a chance to make it.

McKay said Reid has earned the trust from the coaching staff through his leadership and overall IQ. That is a stark contrast to last season when McKay said he was really frustrated with him and Im not sure he liked me so much. I wasnt having any fun coaching him.

But that has changed with Reid being one of the first players off the bench and one of the five who is on the floor in the final minutes. McKay said Reid makes the offense better when hes on the court, and that comes from Reid having the green light to shoot it from any point as the shot clock is winding down.

I dont think I ever lack confidence in my shot. I feel like every shot I take is going in, Reid said. I think that just comes from the reps that Ive taken and the reps Ive completed over the last few years. Im going to continue to take shots because my coaching staff has empowered me to do so.

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The anatomy of a banked-in 3-pointer - Lynchburg News and Advance

Grey’s Anatomy’s T.R. Knight Returns to Shondaland on The Catch – PEOPLE.com

Former Greys Anatomy star T.R. Knight is back in Shondaland!

The actor, 43, has joined the cast of The Catch, which is executive-produced by Greys creator Shonda Rhimes, for season 2 and PEOPLE has the First Look at the actor in action on the ABC drama.

The Catch centers on private investigator Alice Vaughan (Mireille Enos), whose fianc Benjamin Jones (Peter Krause) conned her out of her money before sacrificing himself to save Alice from wrongful imprisonment.

Knight, who spent five seasons on Greys as George OMalley, joins the show as Alices brother.

Youre boyfriend is a conman? Knights character asks in the clip.

Fianc, thank you very much, Benjamin corrects him.

Whatever the status of their relationship, it appears things will get very Mr. & Mrs. Smith between Alice and Benjamin, who point guns at each other at the end of the promo.

Were not going to shoot each other, Benjamin says before giving his statement a second thought. Are we?

Season 2 of The Catch premieres March 9 at 10 p.m. ET on ABC.

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Grey's Anatomy's T.R. Knight Returns to Shondaland on The Catch - PEOPLE.com

La La Land: anatomy of a backlash – Den of Geek UK

Reader, you should have seen the queue: it stretched all the way out of the cinema, down the street, round the corner and on for another half a kilometre or so. This was the line for La La Land at the London Film Festival late last year, and there was a definite hum of enthusiasm in the air.

Hype had already built around the musical since its first screening at the Venice Film Festival a couple of months earlier, and as a result, there were so many people desperate to see the movie at its first London screening that the cinema couldn't accommodate them all. Your humble writer managed to grab one of the last seats in the house - and again, the atmosphere was electric: the audience laughed in all the right places, and as the final credits rolled on Damien Chazelle's airy romance, a ripple of applause went up.

You've probably noted all the critical acclaim by now, and seen the La La Land poster covered in a sea of stars from all those gushing notices. Yet over the past few weeks, the tide has begun to turn against Chazelle's musical. Hadley Freeman wrote an amusing piece about the film's jazz-snob leading man, played by Ryan Gosling.

A more serious criticism argues that La La Land's racially insensitive in its casting, given that it's all about a white guy defending jazz - a form of music created by African Americans. Other commentators have suggested that co-star Emma Stone's character is something of a blank; still others have said that, really, Gosling and Stone's singing and dancing isn't up to much.

Those are only a very brief example of the criticisms levelled at La La Land over the past few weeks - for more a more detailed top-down view, these pieces at the Guardian and the Washington Post will give you just about everything you need. The deeper question, at least for us, relates to the nature of the backlash itself. How can a fairly harmless indie film go from acclaim to fairly comprehensive criticism so quickly?

Based on our years of watching and reviewing movies, here's a theory of how the backlash process works...

Like so many indie flicks, La La Land made its debut at a film festival. On paper, being a critic at a film festival sounds like the best gig in the world: you get to sit around watching movies all day and get paid for it.

The reality, however, is a bit more stressful than it initially sounds. First, you're spending eleven-or-so days watching dozens of films back-to-back. While you might be familiar with some of the movies on offer at any given festival, the whole point of these events is to get an early look at work from up-and-coming directors or filmmakers from more obscure parts of the globe.

This means you could be up bright and early to see an Italian drama for breakfast, before tucking into a Dutch thriller for elevenses, a Japanese horror at lunchtime, a French animation for your mid-afternoon snack, an American biopic for dinner, and so on. The last film might end somewhere around midnight, and then you have to trudge back to your hotel room, a stack of barely-legible notes clutched in your fist, and attempt to write reviews from them all - assuming you can even remember what happened in that film you saw at breakfast. It was Swiss, wasn't it? Yes, probably Swiss.

Now, we're not suggesting for one moment that you should throw a pity party for film critics. Rather, the above might help explain why, when a film comes along that's different or unexpected, weary critics will suddenly jump out of their skins. A musical as light and frothy as La La Land must have felt like a sunny antidote to some of the more brooding works on offer at last year's Venice film festival. As a comparison, Dutch director Martin Koolhoven's Brimstone (which was also in the main competition at Venice) is an exploration of how many horrible things Guy Pearce can do to men, women and livestock in two-and-a-half hours - a Supermarket Sweep of taboo-busting atrocities.

So the festival critics love your movie, and the first wave of reviews are full of five-star verdicts. As the film filters out to other festivals, more critics and cinema lovers are enticed into going to see it after that initial burst of acclaim, and the positive word-of-mouth continues. Gradually, however, the dissenting voices begin to surface: in December last year, for example, critic Daniel Kimmel argued that La La Land is "a film that tries too hard and is always showing how much it's straining." That same month, the National Post's critic Calum Marsh suggested that Chazelle's technique as a director did much to mask his shortcomings as a dramatist.

Within a few short weeks, the cracks have begun to show.

There are certain kinds of movie that awards bodies absolutely love. Movies that celebrate the triumph of the human spirit; movies that showcase the craft of acting. Most of all, Hollywood awards bodies love movies about Hollywood. Like silent-era love letter The Artist, the British Academy, the Golden Globes and the Screen Actors Guild have clutched La La Land to their bosoms. The movie broke records at the Globes; at the Oscars, its 14 nominations puts it alongside All About Eve and Titanic for the most nods given to a single contender.

For most indie filmmakers, awards recognition is a gift from the gods: with a potential audience of millions, even a nomination or two can mean a movie with an otherwise tiny marketing budget can get some much-needed exposure. In the case of a movie like The Artist or La La Land, however, there's the possibility that a sense of suspicion might set in among cinema-goers. Is La La Land really worth all those gold statues, or is this just another example of Oscar voters falling for the hype?

Despite all the gushing reviews from critics and the nominations from awards bodies, it's this stage that's the true turning point. A film's release exposes a movie to the broader public for the first time, obviously, but something else also happens at the same moment: columnists, bloggers, journalists and pundits start filing their opinion pieces.

On the surface, an opinion piece and a review might seem like the same thing - a review is, after all, one person's opinion, albeit backed up by their years of experience and knowledge in one particular field of interest. But reviews are invariably written early, often after one viewing and frequently before a film's release. They're an impression, a snapshot based on an initial screening. This is why movies can sometimes receive a critical drubbing on their theatrical release, and then a more positive reassessment sometime later.

As a quick example, consider Mark Kermode and his change of heart over Steven Spielberg's 2001 film, A.I.: Artificial Intelligence. When the movie first came out, Kermode gave it a negative review; 12 years later, he'd had time to reflect, revisit the movie, and came to the conclusion that he was wrong - so wrong that he even apologised to Spielberg for his initial verdict.

Articles and opinion pieces, unlike reviews, generally come after a period of rumination; writers have had a chance to think about a movie's themes, ideas and flaws. They may have rewatched it a couple of times, talked about it with friends, and come to the conclusion that some of the flaws are more fundamental problems on closer inspection.

This is why, at least in this writer's humble opinion, a movie as seemingly beloved as La La Land can suddenly seem so hated a few weeks later. Reviews are an expression of surprise, a reflection of an initial warm glow left behind by a first viewing; those later pieces are where a film's wider implications are picked apart in more forensic detail.

So if La La Land received a legion five-star reviews on one hand, and criticism for its insensitivity on the other, which is right? The answer, we'd argue, can be both. For a multitude of reasons, La La Land struck a chord with critics when it first emerged last year - and we were among the various outlets who expressed our affection for it. But this isn't to say that La La Land is a perfect movie, or that the flaws found within it mean that it doesn't deserve the praise it's already received.

One of the positive things about our interconnected, online world is that we can read and hear opinions from critics in other countries and from different walks of life. Female writers, like Hadley Freeman, have pointed out the less likeable side of La La Land's central male character, Sebastian, and noted the somewhat flat depiction of its other lead, Mia - both things that may have passed some male cinema-goers by.

Similarly, jazz fans have pointed out flaws in its depiction of their favourite music genre; lovers of classic musicals have argued that La La Land isn't quite in the same league as the films it's quoting; MTV's Ira Madison III writes that, "If you're gonna make a film about an artist staying true to the roots of jazz against all odds [...] you'd think the artist would be black."

Criticisms like these are important; films are made by ordinary, flawed people who are products of their upbringing and their own worldview, so it follows that what they make is also flawed. Singling films out and holding them up for praise is important for the industry as a whole; without it, small films like La La Land, Blue Ruin, It Follows, Lion or Moonlight wouldn't get the word-of-mouth they need. But whether you call them backlashes or critical dissections, the more in-depth discussions of a film's ideas and meaning - whether intended or otherwise - are just as important.

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La La Land: anatomy of a backlash - Den of Geek UK

CEVEC Licenses Cell Lines to NewLink Genetics – Genetic Engineering & Biotechnology News (blog)

CEVEC Pharmaceuticals said today it has granted rights to its CAP GT and CAP Go cell lines to NewLink Genetics for the development and commercialization of vaccines against Zika virus infections.

The value of the licensing agreement was not disclosed. Under the deal, CEVEC is giving NewLink and its affiliates the rights to research, develop, manufacture, and commercialize CAP GT- and/or CAP Go-derived Zika vaccine candidates.

CAP GT is a cell-expression system designed as a novel platform for scalable production of viral vectors for gene therapy. Growing in serum-free suspension culture at high densities, CAP GT cells are intended to propagate a broad spectrum of viral species supporting lentiviral, adenoviral, and adeno-associated viral (AAV) vectors.

According to CEVEC, CAP GT suspension cell-derived viral packaging and producer cell lines are intended to enable better scaleup and competitive production costs compared to adherent cell culture systems.

CAP Go cell lines are used in the recombinant production of complexly glycosylated molecules, such ascoagulation factors and other plasma proteins. In addition to plasma proteins, examples of products made using CAP Go include cytokines, ion channels, virus envelope proteins, high-molecular-mass multimer proteins, and antibodies.

According to CEVEC, CAP Go enables the production of proteins previously out of reach, representing a significant proportion of the human proteome, and proteins difficult to express in conventional cell lines such as Chinese hamster ovary (CHO) cells. The CAP Go expression platform consists of a portfolio of glyco-optimized human suspension cell lines designed for highly efficient production of a broad range of difficult-to-express recombinant proteins with authentic human post-translational modifications or on-demand tailor-made glycosylation patterns.

The joint agreement is a strong endorsement of our CAP system and represents another important step toward establishing CEVEC's technologies as the new global industry standard for viral vector and vaccine development, CEVEC CEO Frank Ubags said in a statement.

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Myriad Genetics: Fairly Valued? – Barron’s (blog)

By Ben Levisohn

When a stock has been beaten up as badly as Myriad Genetics (MYGN) hasits dropped 57% during the past 12 monthsit doesnt take much to move it higher. So it shouldnt come as too much of a surprise that shares of Myriad are soaring today after the genetic testing company beat earnings forecasts and offered upbeat guidance.

Myriad reported a profit of 26 cents a share, topping forecasts for 24 cents, on revenue of $196.5 million, beating the Street consensus for $190.1 million. Myriad also said it expects to earn between $1 and $1.05 in 2017, ahead of analyst forecasts of 98 cents.

So is the worst over? Maybe, but Cowens Doug Schenkel and team argue that Myriads shares are fairly valued. They explain why:

Myriad remains in a transformation phase and visibility on the revenue growth outlook continues to be limited. For example, there are several key decisions in the next 3 months that could affect Myriads outlook, including: (1) a CMS Editorial review board to review CPT coding for hereditary cancer panels (Feb. 10-11; link); (2) a final Vectra DA CMS reimbursement decision (LCD comment period ends March 23); (3) a final Prolaris LCD intermediate risk decision (comment period ends March 23); and (4) a UHC contract decision for hereditary cancer testing (current contract ends in May).

Although the share price continues to decline, we still believe shares are about fairly valued considering the number of uncertainties across business segments. Relative to peers Myriad still trades at a slight P/E premium, but at a ~30% EBITDA discount.

Shares of Myriad Genetics have jumped 10% to $16.99 at 10:38 a.m. today.

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Myriad Genetics: Fairly Valued? - Barron's (blog)

The Tragic Story Of Soviet Genetics Shows The Folly Of Political Meddling In Science – IFLScience (blog)

A few years ago, one of us (Ian) was lucky enough to be invited to visit the N.I. Vavilov Institute of Plant Industry in St Petersburg, Russia. Every plant breeder or geneticist knows of Nikolai Vavilov and his ceaseless energy in collecting important food crop varieties from all over the globe, and his application of genetics to plant improvement.

Nikolai Vavilov was pilloried because he wasnt a political favourite in Soviet Russia. Library of Congress. New York World-Telegram & Sun Collection

Vavilov championed the idea that there were Centres of Origin (or Diversity) for all plant species, and that the greatest variation was to be found in the place where the species evolved: wheat from the Middle East; coffee from Ethiopia; maize from Central America, and so on.

Hence the Centres of Origin (commonly known as the Vavilov Centres) are where you should start looking to find genotypes the set of genes responsible for a particular trait with disease resistance, stress tolerance or any other trait you are looking for. This notion applies to any species, which is why you can find more human genetic variation in some African countries than in the rest of the world combined.

By the late 1920s, as director of the Lenin All-Union Academy of Agricultural Sciences, Vavilov soon amassed the largest seed collection on the planet. He worked hard, he enjoyed himself, and drove other eager young scientists to work just as hard to make more food for the people of the Soviet Union.

However, things did not go well for Vavilov politically. How did this visionary geneticist, who aimed to find the means for food security, end up starving to death in a Soviet gulag in 1943?

Heroic science?

Enter the villain, Trofim Lysenko, ironically a protg of Vavilovs. The notorious Vavilov-Lysenko antagonism became one of the saddest textbook examples of a futile effort to resolve scientific debate using a political approach.

Lysenkos theories went against the latest science, but prevailed due to politics. Wikimedia

Lysenkos name leapt from the pages of history and into the news when Australias Chief Scientist, Alan Finkel, mentioned him during a speech at a meeting of chief scientists in Canberra this week.

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The Tragic Story Of Soviet Genetics Shows The Folly Of Political Meddling In Science - IFLScience (blog)

Animal genetics co-op LIC reports a 21 per cent profit lift in half year result – Stuff.co.nz

RURAL REPORTERS

Last updated17:43, February 9 2017

ANDY JACKSON

LIC has lifted profits in its half year result.

Tough cost-cutting has helpedLivestock Improvement Corporation boostitsprofit after tax by 21 per cent in the latest half year result.

The rise to $19.3 million reflectedthe Hamilton-based animal genetics company's solid performance in artificial breeding and herd testing, chairman Murray King said.

LIC's total revenue for the six months endingNovember 30, 2016was $131m, 9.6 per cent down on the $145m achieved during the same period in 2015.

King said it reflected tough but necessary cost reduction measures within the business. It had been a tough environment on farms for the past couple of years and LIC had weathered the storm and was in good shape to face the challenges ahead.

READ MORE: *LIC general manager NZ Markets resigns for personal reasons *Capital restructuring on the cards for LIC *Taranaki farmers remain unhappy with new LIC structure

While the downturn had reduced the national dairy herd the genetics LIC selected and supplied to farmers were responsible for breeding more than three-quarters of all cows, with sales similar to those achieved last year, resulting in an increased market share.

Demand for LIC's herd testing services had rebounded, with sales up on the same time last year. LIC had continued its transformation programme to protect and grow the co-operative, he said.

"We've scrutinised every part of the business to actively manage and minimise our operating costs, and look for better ways of doing business, with minimal impact to farmers or where possible improving it. This focus will continue through the rest of the year and beyond."

LIC's business, particularly for artificial breeding washighly seasonal. Itshalf year results provide most of artificial breedingrevenues but not a similar proportion of total costs, and are therefore not indicative of the second half, nor the full year, result. No dividend is therefore declared at half year.

The business wasforecasting a return to a modest level of profitability for the full year.

-Stuff

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Animal genetics co-op LIC reports a 21 per cent profit lift in half year result - Stuff.co.nz

Jonathan Singer, original UCSD faculty member, dies at 92 – The San Diego Union-Tribune

Jonathan Singer, who helped build UC San Diego into a world leader in molecular and cell biology as one of the schools original biology faculty members, died Feb. 2 in La Jolla. He was 92.

Singer was on the chemistry faculty at Yale University when he was lured toUC San Diegoin 1961 by David Bonner, the founding chair of the universitys biology department.

Bonner believed that studying biology at the molecular level with chemistry as its basis would revolutionize the biological sciences and Singer, who had been mentored as a postdoctoral fellow by Nobel LaureateLinus Pauling, would be a perfect fit.

He was Bonners right-hand man and shared his vision of building a new kind of biology department focused on molecular approaches to all branches of the biological sciences, one that would be deeply interconnected by collaborative research, said Bill McGinnis, dean of the Division of Biological Sciences.

After Bonners death in 1964, Singer took over as the chair of the department and carried out much of his work, including planning the construction of the first building of the future School of Medicine.

In 1972, he and biochemist Garth Nicolson published a groundbreaking paper in Science on the Fluid Mosaic Model of the cell membrane, which would prove to explain a wide range of critical cellular processes, including cell-cell signaling, cell division, membrane budding and cell fusion.

In the last two decades of his life, Singer focused with colleague Nazneen Dewji on a novel approach to a treatment of Alzheimers disease that centered on the interaction between two cell membrane proteins beta-amyloid precursor protein and presenilin.

Singer was elected to the National Academy of Sciences in 1969 and the American Academy of Arts and Sciences in 1971, and hewon the E. B. Wilson Award from the American Society for Cell Biology in 1991.

He also was a University Professor of the University of California, an honor that has been awarded to only 41 members of the UC faculty.

He is survived by his daughter Julianne, son Matthew, niece Laura and nephew Bill, as well as granddaughter Grace and grandson Michael.

In lieu of flowers, the family requests that donations be made to the Alzheimers Association.

gary.warth@sduniontribune.com

Twitter: @GaryWarthUT

760-529-4939

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Jonathan Singer, original UCSD faculty member, dies at 92 - The San Diego Union-Tribune