Grey’s Anatomy’s Justin Chambers: Is Alex Karev Out of Jail for Good and How He Can Still ‘Thrive’ – PEOPLE.com

What will become of Alex Karev?

Last weeksGreys Anatomy brought thepediatric surgeon back after it was revealed hed taken a plea deal and jail time for a violent outburst against surgical intern Dr. Andrew DeLuca (Giacomo Gianniotti). And yet! when Karev showed up at Meredith Greys (Ellen Pompeo) door at the end of the episode, he was definitely in jail.

Justin Chambers, who plays Karev, is opening up about what exactly Thursdays episode of the hit ABC show will reveal about Alex, including some changes his character is set to undergo in weeks, and perhaps years to come.

Im happy hes not in jail! he told Entertainment Weekly, adding, Youre going tofind out in this next episode how he got off, but Im happy hes going back to the hospital, and hes gonna be back working in [pediatrics]where he belongs, and curing young people.

He toldVariety,I think having everything taken from him I think he learned a lot there, but I think he appreciates being in peace and hes very good at what he does and he thrives there.

Chambers,46, sympathizes with Karev:I just hope Alex finds some happiness. Crap. He just never seems to catch a break. Looking forward, though, he gives fans a little hope, saying, Im thinking soon there might be some stability.

Whether that stability happens in his fraught relationship with Camilla Luddingtons Dr. Jo Wilson remains to be seen.

This was a big deal for him to find out shes not who he thought she was, and how do you come back from that? he said to EW.And from what happened, this whole situation with him beating up DeLuca, the misunderstandings and why she lied, its gonna be interesting to see how they can fix this and well find out over the next few episodes.

Chambers added to Variety:He was going to take a plea deal to protect his girl. Theyre not together right now . [and] hes still angry with her, but if anyone knows anything about second chances, its Alex. So he has that to think about. She messed up, but there must be a piece of him that still feels for her. Love just doesnt die like that.

Greys Anatomyairs Thursdays (8 p.m. ET) on ABC.

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Grey's Anatomy's Justin Chambers: Is Alex Karev Out of Jail for Good and How He Can Still 'Thrive' - PEOPLE.com

The New ABCs of Medical School: Anatomy, Biochemistry, and Cooking – Food Tank (blog)

As Hippocrates, the founder of modern medicine, spoke, Let food be thy medicine. However, most medical schools in the United States do not adequately teach nutrition. Several programs, including at Tulane University, are addressing this shortcoming by including cooking classes in their curriculum. The hope is that by teaching future doctors how to cook delicious and healthy meals, they will pass that knowledge on to their patients, improving long-term health.

The rates of obesity and obesity-related diseases are increasing throughout the world according to Prediabetes: A Worldwide Epidemic. The Center for Disease Control reports that nearly half of all deaths in the United States are due to heart attacks, strokes, and diabetes. Entire scientific journals, such as Nutrition and Health, Diabetes, and the Journal of Nutrition, are devoted to examining the relationships between nutrition and health. Research has shown that nutrition is one of the leading causes of and significantly affects the management of diabetes, cardiovascular disease, and aging-related diseases.

There is no clear correlation between policy recommendations and nutrition choices. For example, a study that provided nutrition information to adults at fast-food chains found that simply providing information did not alter consumer choices. Coaching has consistently proven effective at changing eating habits, especially when tailored to an individuals lifestyle and medical history. Many see using doctors as nutrition coaches as a natural extension of a physicians duties and a valuable opportunity for one-on-one intervention. However, a National Institute of Health survey revealed that a majority of primary care physicians do not give diet advice. According to polls reported by the Washington Post, less than 25 percent of doctors feel they are informed enough regarding nutrition to discuss it knowledgeably.

Tulanes program was developed in 2014 to better instruct medical students in nutrition. According to their website, Through hands-on cooking classes, medical students and physicians learn the practical aspects of lifestyle change necessary to help them guide their patients to healthier choices.

The National Academy of Sciences recommends 25 hours of nutrition instruction for medical students, whereas the Tulane course requires 53 hours of culinary classes, 53 hours clinical care teaching, and 53 hours learning nutritional counseling strategies in lifestyle modification. Researchers at Tulane examined the effectiveness of the program and found improvements to the lifestyle of medical participants and significant health benefits to diabetic patients, including improved HbA1c, blood pressure, and cholesterol levels.

To date, 28 other medical schools, two residency programs, and two nursing schools have adapted the Tulane curriculum. Dartmouth, the University of Chicago, the University of Massachusetts, and others have started similar programs within their medical schools. Harvard University partnered with the Culinary Institute of America to offer week-long workshops that have demonstrated improvements in attendees ability to advise patients as well as ameliorating their lifestyle, including cooking more at home, making healthier food choices like whole grains and nuts, and heightened awareness of calorie consumption.

Personally taking culinary classes can improve peoples diets without making a trip to the doctor. Programs in Chicago improve nutrition knowledge and vegetable consumption in children. Community kitchens in Peru taught adolescents and improved their diets. Similar kitchens in Canada have had a similar effect of improving lifestyles and education within several communities. In general, public health researchers find that cooking at home can significantly improve health when the knowledge of good nutrition is applied. For some of the Tulane programs recipes, click here.

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The New ABCs of Medical School: Anatomy, Biochemistry, and Cooking - Food Tank (blog)

Genetics of both virus and patient work together to influence the … – Medical Xpress

February 9, 2017 HIV, the AIDS virus (yellow), are infecting a human cell. Credit: ZEISS Microscopy / Flickr

Viral and human genetics together account for about one third of the differences in disease progression rates seen among people infected with the human immunodeficiency virus (HIV), according to new research published in PLOS Computational Biology. The findings suggest that patient genetics influences disease progression by triggering mutations in the HIV viral genome.

People with HIV experience different rates of disease progression. HIV progresses faster in people with a higher viral loadthe amount of genetic material from the HIV virus found in an infected person's blood.

Previous research has shown that an infected person's genetics and the genetics of their particular HIV strain both influence viral load. Istvn Bartha of cole Polytechnique Fdrale de Lausanne, Switzerland, and colleagues are now the first scientists to investigate the relative impacts of human and viral genetics on viral load within the same group of patients.

The researchers collected patient and viral genetic data from 541 people with HIV. They used a computational modeling method known as linear mixed modeling to determine how human and viral genetics might explain differences in viral load between the patients.

They found that genetic differences between HIV strains explain 29 percent of differences in viral load between patients, while human genetic variation explains 8.4 percent. Together, they explain just 30 percent of viral load variation, indicating that patient genetics exert most of its influence by inducing genetic mutations in the HIV virus as it multiplies inside the patient.

"Our paper demonstrates that the genetic make-up of both the patient and the infecting virus contribute to the clinical course of HIV infection," says study director Jacques Fellay.

Further research with a larger group of patients is needed to confirm and refine the findings. Nonetheless, "combining host and pathogen data gave us new insight into the genetic determinants of HIV control," Fellay says. "A similar strategy could be used to better understand other chronic infectious diseases."

Explore further: New antiretroviral drugs decrease chances of HIV sexual transmission

More information: Bartha I, McLaren PJ, Brumme C, Harrigan R, Telenti A, Fellay J (2017) Estimating the Respective Contributions of Human and Viral Genetic Variation to HIV Control. PLoS Comput Biol 13(2): e1005339. DOI: 10.1371/journal.pcbi.1005339

More than 2 million people were infected by human immunodeficiency virus (HIV) in 2015 via sexual transmission. Researchers from the Bellvitge Biomedical Research Institute (IDIBELL), led by Dr. Daniel Podzamczer, have evaluated ...

Scientists have found potential evidence of Ebola virus replication in the lungs of a person recovering from infection, according to new research published in PLOS Pathogens. The findings could aid research into new treatment ...

(Medical Xpress)A large international team of researchers has conducted a study that has shed some light on the role genetic variation plays on HIV viral load levels in patients infected with the virus. In their paper ...

Individuals infected with HIV exhibit both severe immune deficiency and aberrant inflammation, resulting in susceptibility to secondary infection as the disease progresses. HIV-associated deficiencies in adaptive immune responses ...

Scientists have identified a 'molecular barcode' in the blood of patients with Ebola virus disease that can predict whether they are likely to survive or die from the viral infection.

(HealthDay)In patients with hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), low HCV viral load predicts better long-term surgical outcomes, regardless of the serologic eradication of HCV, according to research ...

Viral and human genetics together account for about one third of the differences in disease progression rates seen among people infected with the human immunodeficiency virus (HIV), according to new research published in ...

A new biologic agentthe most potent of its kind so faris showing early promise as part of a potential new strategy for treating HIV. The drug, known as 10-1074, may also offer a new way to prevent viral infection in ...

A Case Western Reserve University School of Medicine researcher has received a $2.5 million grant from Gilead Sciences, a California-based biopharmaceutical company, to see if two so-far separately-used AIDS treatments are ...

When someone is HIV-positive and takes antiretroviral drugs, the virus persists in a reservoir of infected cells. Those cells hide out in germinal centers, specialized areas of lymph nodes, which most "killer" antiviral T ...

(Medical Xpress)A large international team of researchers has created what they are describing as the most powerful HIV-attacking antibody ever made. In their paper published in the journal Science Immunology, the team ...

A drug developed at the University of Rochester Medical Center extends the effectiveness of multiple HIV therapies by unleashing a cell's own protective machinery on the virus. The finding, published today in the Journal ...

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I never taught Dr ILLUOBE who could ever get my HIV-AIDS cured with his herbal product.despite all these happening to me.I always spend a lot to buy a HIV drugs from hospital and taking some several medications but no relieve until one day i was just browsing on the internet when i came across a great post of ! Williams Fran-ca who truly said that she was been diagnose with HIV and was healed that very week through the help of these great powerful healing spell doctor. sometime i really wonder why people called him Dr ILLUOBE,i never knew it was all because of the great and perfect work that he has been doing that is causing all this. so i quickly contacted him and he ask me some few questions and he said a thing i will never forget that anyone who contacted him is always getting his or her healing in just 6 hours after doing all he ask you so i was amazed all the time i heard that from him ,so i did all things only to see that at the very day which he said i will be healed all the st

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Genetics of both virus and patient work together to influence the ... - Medical Xpress

Company Spotlight: Signal Genetics – RTT News

Shares of molecular genetics diagnostic company Signal Genetics Inc. (SGNL) have gained more than 60% in the last five trading days.

To find biotech stocks with more profit potential, please visit RTTNews' Emerging Biostocks page.

Last October, Signal Genetics and privately-held Miragen Therapeutics Inc. agreed to merge to create a clinical-stage, NASDAQ-listed, Biopharmaceutical Company developing proprietary micro RNA-targeted therapeutics.

As part of the agreement, stockholders of Miragen will become holders of approximately 96% of Signal's outstanding common stock on a fully-diluted basis.

The combined company will be named Miragen Therapeutics Inc., and will trade on the NASDAQ Capital Market under ticker symbol "MGEN." The proposed merger is expected to close in the first quarter of 2017.

Miragen has two product candidates in phase I testing - MRG-106 for patients suffering from cutaneous T-cell lymphoma (CTCL) of the mycosis fungoides (MF) sub-type, and MRG-201, an anti-fibrosis product candidate that is being tested in healthy volunteers.

On November 29, 2016, Signal agreed to sell all of its intellectual property assets relating to MyPRS test to Quest Diagnostics Investments LLC for $825,000, plus an additional $100,000 if Quest exercised the option to require Signal to operate Signal's lab beyond December 31, 2016 (but not later than January 14, 2017).

Myeloma Prognostic Risk Signature, or MyPRS, test analyses the activity of genes to predict whether an individual is at high risk or low risk for early relapse. Knowing the risk of relapse helps to predict patient outcome.

A special meeting of Signal Genetics' stockholders to vote on matters related to the proposed merger with Miragen Therapeutics Inc. and the sale of Signal's MyPRS intellectual property assets is to be held at 9:00 a.m., local time, on February 10, 2017.

In order to regain compliance with the minimum bid price requirement of the NASDAQ Capital Market, a 1-for-15 reverse stock split of common stock was implemented by Signal Genetics on November 7, 2016.

SGNL has traded in a range of $0.12 to $17.74 over the last 52 weeks. The stock closed Thursday's trading at $14.50, up 7.65%. In after-hours, the stock gained another 3.38% to $14.99.

by RTT Staff Writer

For comments and feedback: editorial@rttnews.com

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A primer on Darwin Day: Some religious groups embrace ‘Theistic evolution’ – LancasterOnline

Sunday is International Darwin Day the 208th anniversary of the birth of naturalist Charles Robert Darwin, whose 1859 book, On the Origin of Species, began a controversy that exists to this day.

Sunday also is being proclaimed as Take Darwin to Church Day in various parts of the world. Leaders of the movement, which was initiated by the Council for Secular Humanism, suggest that churches invite science advocates to speak to their congregations.

Darwin has been lauded and maligned over the past 150 years, depending on ones point of view.

Although some religious organizations stridently oppose biological evolution, other groups accept evolution with a twist: they allow for theological considerations.

Theistic evolution, also known as theistic evolutionism or evolutionary creation, allows for the belief that God is the creator of the universe and all life and that evolution is a tool that God used to create human life. That includes astronomical, geological, chemical and biological evolution.

In 2014, Pope Francis suggested a link between evolution and creation. Said Francis: God is not a demiurge or a conjurer, but the Creator who gives being to all things. The beginning of the world is not the work of chaos that owes its origin to another, but derives directly from a supreme Origin that creates out of love. The Big Bang, which nowadays is posited as the origin of the world, does not contradict the divine act of creating, but rather requires it. The evolution of nature does not contrast with the notion of Creation, as evolution presupposes the creation of beings that evolve.

A survey conducted by Pew Research last year found that while 98 percent of scientists associated with the American Association for the Advancement of Science believe humans evolved over time, only 62 percent of Americans overall believe that to be the case.

Among those least likely to believe in human evolution, according to the survey, were evangelical Protestants (57 percent) and Mormons (52 percent.)

In 2008, the Church of England acknowledged it was overly defensive when it dismissed Darwins ideas. In its public apology, the church compared its dismissiveness of Darwins theories to its rejection of Galileos astronomical observations in the 17th century.

Over time, a number of myths about Darwin have cropped up. In response to a request by LNP, Josh Fischel, who teaches religion in the philosophy department at Millersville University, debunked five myths about Charles Darwin.

1. Charles Darwin was an atheist.

While he despised the orthodoxy of traditional religious practices, his writings suggest that he was a deist not an atheist.

2. Charles Darwin had a deathbed conversion to religion.

Its untrue. This myth was started by a woman who never had met Darwin, but who sought to profit from telling a story about this end-of-life conversion experience.

3. The existence of humans is the goal of evolution.

Not true. The purpose of evolution, if you will, is more evolution.

4. The common claim that its just a theory implies that its some kind of speculation.

In fact it is a scientific theory. But scientific theories explain, through the gathering of evidence (in this case, from embryology, archaeology, genetics, etc.) observations we make about the natural world.

In fact, evolution is a descriptive scientific theory that helps us to better understand and predicate the nature and origin of life, but makes no pretensions to how we ought to act or what we should strive for as individuals and as a society.

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The Biochemistry of Love and Herbal Aphrodisiacs – Lawrence, Kansas

Dive deep into this dynamic, hands-on intensive to discover the biochemistry behind love, arousal, connection, and the medicinal plants that can aid us in these completely natural and healthy processes. We will look in-depth at six different powerful aphrodisiac herbs, the phytochemistry of how they work in the body, contraindications, and practical ideas for application. We will finish the class with smelling, tasting and finally making our own Damiana Cordial to take home. Class is taught by Shannon Ryan, Professional Herbalist and Licensed Acupuncturist. Note: While beginners are welcome, content is most suitable for attendees with some basic knowledge of herbal medicine.

~ $35 ~ *Space is Limited and Pre-Registration is Required*

* Call Lawrence Acupuncture to Register (785) 371-1141 or book online at http://www.lawrenceacupuncture.com

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The Biochemistry of Love and Herbal Aphrodisiacs - Lawrence, Kansas

View from the Left: Anatomy of a direct actiongetting creative when Republicans scrap town halls – Daily Kos

Blocking traffic has the added benefit of annoying constituentstheyre inconvenienced, and thats partly the point. In this case, they would be inconvenienced specifically because their representative was too much of a weasel to face her or his constituents at a town hall.

Can you imagine shutting down main streettraffic in a relatively small town with a banner reading: Rep. X, why wont you speak to us? or Rep. X, why wont you protect our health insurance? or Rep. X, dont you dare take away ourSocial Security and Medicare. Its especially bad optics for a representative who hasnt been willing to face voters since Republicans took control of the government.

Another option is catching someone guerilla-style at a relatively informalevent like a bake saleor a barbeque or even at the grocery store. The key is to ask for something concrete and to have someone with a recording device as simple as a phone (and hopefully a steady hand!) to capture the exchange. Practice makes perfect. DREAM activists made national headlines in 2014 when they confronted Hillary Clinton at Tom Harkins annual steak fry.

You may not make national headlines with something that simple, but you can probably make local headlines. And thats just fine. Mr. Zeldin, why arent you holding town halls? Why wont you talk to your constituents? orMr. Coffman, can you promise me I wont lose my healthcare? If you can make it personal, all the better. Local reporters will likely want a follow up interview with you. But keep the questions relatively simple and pointed, and catch yourrepresentativeoff guard in an environment where they dont expect it, if possible. Frankly, you want them to start thinking they might be confronted by protesters anywhere andat any moment. If you get in an elected officialsheadalways wondering where protesters will pop up nextit absolutely changes the way they think and vote.

This leads me to something slightly more complicated that can make a real splash: interrupting your representative at a speech or some type of ticketed event. Something like a fundraiser isthe ultimate safe space for them and usually covered by local media, so youll have an instant audience.

In my book, Dont Tell Me To Wait: How the fight for gay rights changed American and transformed Obamas presidency, I detailed one of the most effective direct actions staged by LGBTQ activists trying to pressure President Obama to move on repealing the militarys dont ask, dont tell policy. They got six tickets to a fundraiser for then-Sen. Barbara Boxer in L.A. It couldnt have been more friendly territory for him. Obamawas also a master at handling hecklers.

But the folks with the protest group GetEQUAL planned a popcorn-style interruption, where they spread out amongst the crowd of roughly 1,000and once one heckler was silenced, another would start up. Most importantly, they felt the courage of their convictions, as many people around the country do right now. Courage and conviction count fora lot in a direct action. And smart planning.

Heres a partialexcerpt from the book:

A couple minutes into the speech, as Obama began touting Senator Boxers contributions to the state, the chanting began. President Obama, its time to repeal dont ask, dont tell, yelled Laura Kanter, who was the first to initiate the protest. The event was being streamed live by CNN, and though it was hard for viewers to hear exactly what Kanter was yelling, Obamas eyes began to wander a bit as her chant interrupted his cadence. A few moments later, he cupped his hand behind his ear for an instant to hear what all the shouting was about. Then he continued on with his speech.

After about a minute, Kanter was removed, and Dan Fotou started up. Fotou was positioned much closer to the president, so he was visible from the stage and his cries were far more audible and difficult to ignore.

Fotou ramped up as Obama told the crowd that Boxer was passionate about fighting for jobsjobs with good wages, jobs with good benefits. But Obama was starting to get distracted; he and Fotou locked eyes for a moment.

Its time to repeal dont ask, dont tell! Fotou yelled.

Obama stopped abruptly, looked straight at his detractor, then returned, We are going to do that! Fire flared in his eyes momentarily, then fell away as he pointed at Fotou, saying, Hey, hold on a second, hold on a second. We are going to do that. [...]

Just as Obama headed into the familiar territory of job loss and the economy, Zoe Nicholson picked up where Fotou left off. Obama upped his decibel, trying to push past the racket. But finally, he simply stopped, leaving Nicholson an opening to land an audible blow.

Its time for equality for all Americans! she shouted.

Obama glared at her. Im sorry, do you want to come up here? Obama said, raising his hand and waving her to the stage. []

The protesters managed to hijack Obamas speech for about eight minutes. Itwas activist gold for multiple reasons: it made national headlines, conveyed a specific message, and forced a conversation among White House aides on a topic that wasnt on their front burner at that moment. The activistslater found out that while repealing the militarys gay ban hadnt been discussed on Air Force One on the way out Los Angeles, it dominated conversation on the way back.

This of course is a more complexaction that requires a lot of planning and a support team (as stopping traffic would). Its also never popular to take on a politician in a room full of her or hissupporters, not to mention the fact that challenging Obama at an event for a Democratic senator was controversial even among activist circles. But it can also be incredibly effective. And while youre likely to be removed, you probably wont get arrested. Just dont expect to win any popularity contests with other attendees. Themain point one way or the other is that youre anguished about somethingso anguished, in fact, that if you have to do something unpopular, so be it.

Dont get me wrongtown halls are a great setting in which to reach your representative, and voters across the country have been making national headlines doing it.But if Republicans take those away, as they increasinglyseem to be doing,not to worry. You can stage a very effective protest that makes waves with less than a dozen people. It just needs to be well-planned, well-executed, and include a sharp message.

As Margaret Mead once said, Never doubt that a small group of thoughtful, committed citizens can change the world; indeed, it's the only thing that ever has.

If people have other creative ideas for successful actions that they have seen used or even participated in, SHARE THEM BELOW! (Sorry for all capstheyre all the rage these days.)Links to news stories are encouraged.

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View from the Left: Anatomy of a direct actiongetting creative when Republicans scrap town halls - Daily Kos

UNM Exercise Physiology Lab seeks 30 subjects for weight loss study – UNM Newsroom

The UNM Exercise Physiology Lab is looking for healthy adults ages 18 to 65 years to participate in a weight loss study.

The study involves 12 weeks of health coaching to determine if health devices influence body weight, physical activity levels and select blood-borne markers of health like fasting blood glucose, hemoglobin A1c and insulin.

Participants must have a Body Mass Index (BMI)of greater or equal to 30 BMI kg/m^2, must take less than 7,000 steps per day, and must have and iPhone or Android smart phone.

Those who participate will be randomly assigned to one of two intervention groups, a video conferencing or in-person group or a control group.

The Control group must dedicate 44 hours to the study, twohours for pre and post testing and three and a half hours of MyFitnessPal inputting per week.

The Intervention group must dedicate 54 hours to the study, twohours for pre and post testing, three and a halfhours of MyFitnessPal inputting per week and nine and a half hours of health coaching.

There is no compensation for participating in this study.

For more information, contact Kelly Johnson 505-322-5715 kjohnson4@unm.edu or Dr. Ann Gibson at 505-277-2248 alg@unm.edu.

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UNM Exercise Physiology Lab seeks 30 subjects for weight loss study - UNM Newsroom

41 participants attend NFABD’s physiology course – Borneo Bulletin Online

| Fadhil Yunus |

THENational Football Association of Brunei Darussalam (NFABD) has made efforts to combine sports science in the field of football coaching with a physiology course in collaboration with the High Commission of the Republic of Singapore at the NFABD House which began yesterday.

Morni bin Zakaria, Executive Committee Member of NFABD, said that psychology is a study of the function of body, anatomy, organs and interactions with the environment.

In this case, interactions with physiology is interrelated and also needed in football, the guest-of-honour said during an opening ceremony.

The NFABD executive committee member advised participants to seize the opportunity to comprehend better the benefits which will be presented in the course whether it is in theory or practical.

The three-day physiology course conducted by an established expert in Sports Medicine and Physiology at the Singapore Sports Institute, Dr Abdul Rashid Aziz, will focus on the extensive studies on athletes conditions and training during Ramadhan.

The short course, which ends on Wednesday, also offers a range of theoretical and practical case studies such as Muscles and Energy Systems, Training Principles, Physiological demands in Football, Aerobic and Anaerobic Training, Training Load and many more.

Officials and participants in a group photo. KHAIRIL HASSAN

Morni asserted that the participants can gain insight to Dr Abdul Rashids vast experience and expertise in the field of sports science despite the short length of the course.

He also took the opportunity to express his gratitude to Lim Hong Huai, the High Commissioner of the Republic of Singapore to Brunei Darussalam, for providing cooperation and support to NFABD efforts in bringing in an expert from Singapore.

A total of 41 local head and assistant coaches from the teams in the DST Super and Premier Leagues, physical education coaches from the Ministry of Education, coaches from the Department of Youth and Sports and NFABD staff coaches are currently taking part in the course.

The executive committee member added that it already serves as a great opportunity to the participants as it can be used as well as possible in enhancing their knowledge in the field of coaching as an added value in expanding their own expertise to be applied to football players.

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41 participants attend NFABD's physiology course - Borneo Bulletin Online

Fighting Depression? Neuroscience Says This May Reduce … – Inc.com

Depression is one of the most common mental health disorders in the United States. It affects over 15 million adults annually, or 6-7 percent of the entire adult population. It is so common, in fact, that nearly everyone has either been affected by it personally or is involved in some way with someone who has/is.

Depression has serious costs to both individuals as well as employers. Major Depressive Disorder is the leading cause of disability in the U.S. in those aged 15 to 44, and depression is estimated to cost employers up to $44 billion annually. It ranks third in workplace issues, preceded only by family crisis and stress.

Now, neuroscience research has identified a stunningly effective yet simple way to significantly reduce depression symptoms: combining aerobic exercise with meditation.

The study comes out of work on neurogenesis, the study of how new neurons are created and develop in the brain.

In essence, neurogenesis researchers hypothesized that as depressive symptoms emerge, the production of new cells decreases. They noted that trauma and stressful life events are already known to impair neurogenesis, and that the literature has already established that aerobic exercise can significantly increase the number of new cells a brain creates.

The problem is what happens after aerobic exercise: a great number of new cells die just weeks after being created. And if they don't join the brain's circuitry, they can't bolster the brain, uplift mood, help a person experience resilience, or create a more robust sense of wellbeing.

Fortunately, while new neurons can die, they can also be rescued, which is where meditation comes in. It turns out that when novel learning experiences challenge the mind, new neurons are "saved."

"Mental training can rescue new neurons from death as long as the learning experience is new and effortful," the researchers state. "Collectively, these findings suggest that aerobic exercise increases the production of new neurons in the adult brain, while effortful mental training experiences keep a significant number of those cells alive."

The study, published in Translational Psychiatry, outlined how the research was conducted: The neuroscientists developed a mental and physical (MAP) training plan for participants, which combined focused attention meditation with aerobic exercise.

Both the control group and the group with major depressive disorder (MDD) started with 30 minutes of focused attention meditation, followed by 30 minutes of aerobic exercise. They completed this combination twice a week.

During the meditation portion, participants were instructed to focus on the present moment, refocusing on their breathing if thoughts drifted to the past or future. According to research, this helps those with depression (not to mention the rest of us) "accept moment-to-moment changes in attention." This was followed by 30 minutes of "moderate-intensity" aerobic exercise.

Remarkably, the study found a nearly 40 percent decrease in depressive symptoms after just eight weeks of the training. They described these results as "robust."

As Tracey Shors, one of the study authors said, "Scientists have known for a while that both of these activities alone can help with depression ... But this study suggests that when done together, there is a striking improvement in depressive symptoms along with increases in synchronized brain activity."

The researchers also pointed out that while the norm for treating depression has involved the prescription of psychotropic drugs like Zoloft, Prozac, Celexa, and Lexapro, these drugs can have limited efficacy and can also lead to intense and disruptive side effects. Part of the excitement over these results is the fact that the practices involved are free, immediately accessible, and have no adverse side effects.

Interestingly, in addition to student participants, the research group also provided MAP training to young mothers living at a residential treatment facility. The young women involved had experienced homelessness in the past, and had displayed severe depressive symptoms as well as elevated levels of anxiety.

After eight weeks of MAP, they too reported a significant reduction in symptoms of both depression and anxiety. They reported feeling much more motivated and able to focus positively on their lives -- at a time when such an attitude was imperative.

"We know these therapies can be practiced over a lifetime and that they will be effective in improving mental and cognitive health," said lead researcher Brandon Alderman. "The good news is that this intervention can be practiced by anyone at any time and at no cost."

Amen.

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Fighting Depression? Neuroscience Says This May Reduce ... - Inc.com