BMC Neuroscience Archives – Retraction Watch at Retraction Watch – Retraction Watch (blog)

Stanley Rapoport. Source: NIH

Neuroscientist Stanley Rapoportjust cant catch a break.

Rapoport, whos based at National Institute on Aging, is continuing to experience fallout from his research collaborations, after multiple co-authors have been found to have committed misconduct.

Most recently,Rapoport has hadfour papers retracted in three journals, citingfalsified data in a range of figures. Although the notices do not specify how the data falsification occurred,Jagadeesh Rao, who was recentlyfound guilty of research misconduct,iscorresponding author on all four papers.

Back in December, Rapoport told usthat a number of retractions [for] Rao are still in the works: Read the rest of this entry

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BMC Neuroscience Archives - Retraction Watch at Retraction Watch - Retraction Watch (blog)

Neuroscience says listening to this song reduces anxiety by up to 65 percent – AOL

Everyone knows they need to manage their stress. When things get difficult at work, school, or in your personal life, you can use as many tips, tricks, and techniques as you can get to calm your nerves.

So here's a science-backed one: make a playlist of the 10 songs found to be the most relaxing on earth.

Sound therapies have long been popular as a way of relaxing and restoring one's health. For centuries, indigenous cultures have used music to enhance well-being and improve health conditions.

Now, neuroscientists out of the UK have specified which tunes give you the most bang for your musical buck.

INC. TODAY'S MUST READS: Be the Most Persuasive Person in the Room: 9 Things Highly Influential People Always Do, According to Science

The study was conducted on participants who attempted to solve difficult puzzles as quickly as possible while connected to sensors. The puzzles induced a certain level of stress, and participants listened to different songs while researchers measured brain activity as well as physiological states that included heart rate, blood pressure, and rate of breathing.

According to Dr. David Lewis-Hodgson of Mindlab International, which conducted the research, the top song produced a greater state of relaxation than any other music tested to date.

In fact, listening to that one song -- "Weightless" -- resulted in a striking 65 percent reduction in participants' overall anxiety, and a 35 percent reduction in their usual physiological resting rates.

That is remarkable.

Equally remarkable is the fact the song was actually constructed to do so. The group that created "Weightless", Marconi Union, did so in collaboration with sound therapists. Its carefully arranged harmonies, rhythms, and bass lines help slow a listener's heart rate, reduce blood pressure and lower levels of the stress hormone cortisol.

When it comes to lowering anxiety, the stakes couldn't be higher. Stress either exacerbates or increases the risk of health issues like heart disease, obesity, depression, gastrointestinal problems, asthma, and more. More troubling still, a recent paper out of Harvard and Stanford found health issues from job stress alone cause more deaths than diabetes, Alzheimer's, or influenza.

In this age of constant bombardment, the science is clear: if you want your mind and body to last, you've got to prioritize giving them a rest. Music is an easy way to take some of the pressure off of all the pings, dings, apps, tags, texts, emails, appointments, meetings, and deadlines that can easily spike your stress level and leave you feeling drained and anxious.

Of the top track, Dr. David Lewis-Hodgson said, "'Weightless' was so effective, many women became drowsy and I would advise against driving while listening to the song because it could be dangerous."

So don't drive while listening to these, but do take advantage of them:

10. "We Can Fly," by Rue du Soleil (Caf Del Mar)

9. "Canzonetta Sull'aria," by Mozart

8. "Someone Like You," by Adele

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7. "Pure Shores," by All Saints

6. "Please Don't Go," by Barcelona

5. "Strawberry Swing," by Coldplay

4. "Watermark," by Enya

3. "Mellomaniac (Chill Out Mix)," by DJ Shah

2. "Electra," by Airstream

1. "Weightless," by Marconi Union

I made a public playlist of all of them on Spotify that runs about 50 minutes (it's also downloadable).

INC. TODAY'S MUST READS: All Extremely Confident People Give Up These 13 Habits

There's also a free 10-hour version of "Weightless" available if you want a longer listening experience.

RELATED: The most stressful jobs in America

11 PHOTOS

The most stressful jobs in America

See Gallery

Broadcaster

Stress score: 47.93

(mediaphotos via Getty Images)

Taxi driver

Stress score: 48.18

Public relations executive

Stress score: 48.50

(Hero Images via Getty Images)

Corporate executive (senior)

Stress score: 48.56

(Chris Ryan via Getty Images)

Newspaper reporter

Stress score: 49.90

(mediaphotos via Getty Images)

Event coordinator

Stress score: 51.15

(Jupiter Images)

Police officer

Stress score: 51.68

(Juanmonino via Getty Images)

Airline pilot

Stress score: 60.54

(MatusDuda via Getty Images)

Firefighter

Stress score: 72.64

(stevecoleimages via Getty Images)

Enlisted military

Stress score: 72.74

(MivPiv via Getty Images)

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Neuroscience says listening to this song reduces anxiety by up to 65 percent - AOL

Teaching Robots "Manners": Digitally Capturing And Conveying Human Norms – ECNmag.com

Advances in artificial intelligence (AI) are making virtual and robotic assistants increasingly capable in performing complex tasks. For these smart machines to be considered safe and trustworthy collaborators with human partners, however, robots must be able to quickly assess a given situation and apply human social norms. Such norms are intuitively obvious to most peoplefor example, the result of growing up in a society where subtle or not-so-subtle cues are provided from childhood about how to appropriately behave in a group setting or respond to interpersonal situations. But teaching those rules to robots is a novel challenge.

To address that challenge, DARPA-funded researchers recently completed a project that aimed to provide a theoretical and formal framework for what norms and normative networks are; study experimentally how norms are represented and activated in the human mind; and examine how norms can be learned and might emerge from novel interactive algorithms. The team was able to create a cognitive-computational model of human norms in a representation that can be coded into machines, and developed a machine-learning algorithm that allows machines to learn norms in unfamiliar situations drawing on human data.

The work represents important progress towards the development of AI systems that can intuit how to behave in certain situations in much the way people do.

The goal of this research effort was to understand and formalize human normative systems and how they guide human behavior, so that we can set guidelines for how to design next-generation AI machines that are able to help and interact effectively with humans, said Reza Ghanadan, DARPA program manager.

As an example in which humans intuitively apply social norms of behavior, consider a situation in which a cell phone rings in a quiet library. A person receiving that call would quickly try to silence the distracting phone, and whisper into the phone before going outside to continue the call in a normal voice. Today, an AI phone-answering system would not automatically respond with that kind of social sensitivity.

We do not currently know how to incorporate meaningful norm processing into effective computational architectures, Ghanadan said, adding that social and ethical norms have a number of properties that make them uniquely challenging. There seems to be an enormous number of these norms, yet they are highly context-specific and only a relevant subset of them get activated, depending on the situation. Moreover, they seem to exist in an organizational hierarchy but can also be activated in horizontal bundlesnetworks of norms tied together by the contexts in which they apply and triggered by certain context-specific features of the world. They can be in conflict with one another but they are also continuously being updated.

Further complicating matters, norms are activated extremely quickly. Thats something we are all familiar with, Ghanadan said, since normal people detect norm violations very quickly! And in people, new norms or their preconditions for activation are learned into the already complex norm network through not just one but rather a variety of modalities, such as observation, inference, and instruction. The uncertainty inherent in these kinds of human data inputs make machine learning of human norms extremely difficult, Ghanadan said.

Ultimately, for a robot to become social or perhaps even ethical, it will need to have a capacity to learn, represent, activate, and apply a large number of norms that people in a given society expect one another to obey, Ghanadan said. That task will prove far more complicated than teaching AI systems rules for simpler tasks such as tagging pictures, detecting spam, or guiding people through their tax returns. But by providing a framework for developing and testing such complex algorithms, the new research could accelerate the day when machines emulate the best of human behavior.

If were going to get along as closely with future robots, driverless cars, and virtual digital assistants in our phones and homes as we envision doing so today, then those assistants are going to have to obey the same norms we do, Ghanadan said.

At some point, it may even be a robot behind that desk at the library, raising its finger and saying, Shhhh!

The work was conducted by researchers at Brown University and Tufts University, led by Bertram Malle at Brown.

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Not Quite Rational Man – City Journal

For more than a century, neoclassical theory dominated economic thinking. Neoclassical economics is a theory based on three key assumptions: individuals have rational preferences; individuals maximize utility, while firms maximize profits; and people choose independently, based on available information. As with any widely adopted theory, neoclassical economics has huge merits, but it also suffers from important shortcomings.

One increasingly acknowledged flaw of neoclassical theory is its oversimplified model of human nature, known by academics as homo-economicus. Homo-economicus is an efficient calculating machine, someone who always knows what he wants and how to get it (that is, he knows his utility and how to maximize it). But people dont always know what they want, and if they do, they dont know why they want it or how to get it. Humans are not cold, rational calculators. They are emotional beings, tricked easily with math; but they are also incredibly creative and fantastic social learners. Is it possible to build an economic theory that takes humans as they are? Or is the complexity of the economy too great for there ever to be a theory that includes the more esoteric aspects of human behavior, such as social learning, emotions, and imagination?

The good news is that, when it comes to building such a theory, economists do not have to work alone. For decades, scholars from a variety of disciplines have been exploring the consequences of these less rational aspects of human behavior. As the ideas of these outsiders have begun to penetrate the economic community, they have given rise to what I call post-neoclassical economics. This is a body of knowledge that incorporates not only the findings of psychiatrists and behavioral scientists but also those of evolutionary geographers, sociologists, anthropologists, political scientists, historians, development experts, and even some physicists. These nontraditional thinkers have explored the role of social networks and political institutions, as well as innovation, imagination, and collective learning in our study of the economy.

Neoclassical economics succeeded by translating the world into an accepted paradigm, which was delineated by some foundational assumptions. Post-neoclassical economics, by contrast, is a more methodologically agnostic approach, which considers rational agency as just one of many possible models of human behavior. Indeed, what unifies the post-neoclassical approach is the desire to understand economic behavior using any empirically valid methods, no matter in what field they originated. Evolutionary geographers, for example, will borrow methods from, say, network science, if that helps them improve their grasp of regional economic diversification. Behavioral economists dont hesitate to draw on psychology. These interdisciplinary dialogues create bridges that promote learning and advance our knowledge of how economies operate.

In recent decades, some post-neoclassical work has emerged as a new economic mainstream. The research of psychologists like Daniel Kahneman and of political scientists like Elinor Ostrom has been validated with the highest honor in the economics field: the Nobel Prize. Of course, describing all of post-neoclassical economics is beyond the scope of a single essay. So here I will explore just a few examples of the emerging post-neoclassical paradigm. First, Ill focus on the study of the economic consequences of emotion, now a relatively mature field. Then I will venture into more uncharted territory, which includes the study of imagination and of collective learning.

The study of emotions and their impact on decision making was pioneered by psychologists, including Kahneman, Amos Tversky, Dan Ariely, Jonathan Haidt, and Daniel Gilbert. Their theories initially met resistance from economists, despite being empirically valid. Part of this resistance is explained in an essay by Milton Friedman, who argues that the assumptions of economic theory dont have to be empirically valid, as long as they predict the behaviors observed. The analogy he uses is that of an expert billiards player, who performs as if he were skilled at calculating the trajectories of balls using the laws of physicseven if he knows nothing about physics. A physicist could do a reasonable job of explaining the players actions in the game. Economic models, Friedman says, can similarly be empirically wrong about the actual motivations of economic actors, but justifiable if they predict their behavior correctly. Some neoclassical theorists use Friedmans analogy to defend the use of empirically invalid models of human behavior. Yet for that argument to be right, we would have to reject economics as a science. I think that would be too much to lose.

Instead, I suggest that we borrow from the epistemology of physics, psychology, and computer science, and reinterpret the billiards analogy in that light. A physicist modeling the trajectory of a billiard ball would not claim to have a model of the player but rather, one only of the ball. A psychologist or computer scientist, on the other hand, would probably argue that the billiards player performed the calculations implicitly, by an intuitive system that is accurate but nonnarrativelike the neural networks involved in deep learning, if you are a computer scientist, or using what Kahneman calls system one, if you are a psychologist.

Most scientists, in my experience, agree that no theory, including economic theory, can be excused from empirical testing of its underlying assumptions (even if Friedman says that it should). Think of the Higgs boson (a.k.a. the God particle), which high-energy physicists used for half a century as a theoretical construct to perform calculations. Yet they never accepted the Higgs boson as real until it was confirmed in experiments at CERN, the European Organization for Nuclear Research, in a feat that required a 27-kilometer-long tunnel at the border of France and Switzerland. What makes science science is not the use of mathematical theories but the experiments and observations that validate the theories.

Economics is a sciencea beautiful scienceand is thus subject to this principle. (See Economics Does Not Lie, Summer 2008.) One of the unifying ideas of post-neoclassical economists has been to prioritize empirical findings over theories. If the theory does not match the empirical finding, the theory has to go.

Psychologists have been at the forefront of deepening our understanding of human decision making and how emotions shape our choices. In his 2006 book Stumbling on Happiness, Daniel Gilbert considers both emotions and imagination to explain how our thoughts are distorted when we think about the future and the past. By citing a range of experiments and crafting clever analogies, Gilbert shows that when humans think about the past or the future, they fill in the blanks automatically and unconsciously. We suffer from presentism, a cognitive bias that limits our ability to imagine ourselves as hungry when were full or as happy when were sad. Ultimately, the way we see the future or evaluate the past is based on hedonic assessments, where our present feelings are powerful factors that we cannot ignore. Our choices do not represent coldhearted rational calculations; were decision-making agents whose choices are inevitably influenced by our present emotions.

One of the unifying ideas of post-neoclassical economists has been to prioritize empirical findings over theories.

Jonathan Haidts work also explores the role of emotions in decision making, though he focuses sharply on moral choicesdecisions in which the answer is good or bad, instead of true or false, or a number. Making moral choices requires performing mental acts that are quite different from, say, calculating the cost of a 5 percent interest rate on a 20-year mortgage. Moral choices are complex computations that scholars have tried to explain for centuries, using one of two hypotheses. The first, the rationality-first hypothesis, assumes that humans assess the consequences of their moral choices by anticipating whom an action will harm and how bad the damage will be. This resembles how a neoclassical economic model would operate: here, humans are harm-minimizers who construct behavioral heuristics encoding their rational decision making.

The second hypothesis of moral choice is that humans do not think rationally first but that they make quick emotional decisions that their brains later rationalize, composing a narrative in support of the choice. In this emotions-first view, rationality is like a lawyer hired to justify decisions made by our feelings. So when psychologists ask one of their cleverly crafted, albeit sometimes weird, moral questionsis it wrong to have sex with a frozen chicken (if nobody sees you)?we get a gut feeling justifying our answer first (yes, its wrong!) and a stream of words justifying it later. In his book The Righteous Mind, Haidt presents evidence that the emotions-first mechanism is the dominant way by which we make moral choices.

More examples of the importance of emotions in human behavior can be found in the work of Daniel Kahneman and Amos Tversky, the famous duo who begot the field of behavioral economics. Here, I will focus on just one of their contributions: prospect theory, which explains some common, yet extreme, situations, where neoclassical economic theory failsfor example, when people buy lottery tickets or pay large settlements for frivolous lawsuits. Neoclassical economics fails to explain these situations because it assumes that, in uncertain situations, people will pay the expected value of an item. For instance, in a lottery with 1 million tickets, and a prize of $1 million, neoclassical theory predicts that people should buy tickets only when they cost less than one dollar. In a frivolous lawsuit, where people have only a 1 percent chance of losing $1 million, neoclassical theory predicts that settlements should not be larger than $10,000. But the fact that people buy lottery tickets at prices higher than their expected value, and settle frivolous lawsuits by paying more than their expected loss, tells us that we do not weigh our decisions using their expected economic value, at least in these extreme situations.

Prospect theory says that the connection between decision weight and expected values is not linear, as neoclassical economics would have predicted, but S-shaped. That means that people deviate from rationality when the cost of a decision is small and the potential benefit is large (lottery tickets), or when the loss is unlikely but could be substantial (the frivolous lawsuit). The frivolous-lawsuit calculation is an example of loss-aversion, the psychological bias that makes people value the things they have at roughly 2.5 times the value of those same things when they dont have them. Emotional attachment is pricey and real.

Cognitive biases like those embodied in Kahneman and Tverskys prospect theory, or the presentism described by Gilbert, are so numerous that some people see their sheer number as discrediting behavioral economics. In other words, the existence of such a large number of biases prevents the development of a single coherent theory. Yet for me, this embarrassment of empirical riches is a sign of progress. Consider particle physics. Decades ago, a myriad of particles had been discovered, but physicists at first didnt know how to assimilate them into a single model. Now, all these particles are seen as a manifestation of a few quarks, leptons, and bosons. Psychology today faces a similar abundance of findings, but the wealth of new evidence is not reason for despair; rather, it provides the fertile empirical ground that post-neoclassical economics needs to model human behavior more accurately. As some have suggested, these biases could be manifestations of shortcuts that evolved to help us make quick decisions in an information-deprived social environment. Id bet that, over the next few decades, some plausible unifying theories will be proposed in this field.

In neoclassical economics, agents use their imagination to make purchasing and production decisions. In reality, people use their imagination for far more than just commercial strategic choices. In fact, one could argue that the main contribution that imagination makes to the economy is creative instead of strategic: imagination is more important to help us design products than to help us decide what products to exchange.

The creative aspects of imagination, however, are not the bread and butter of neoclassical theory. Creativity and imagination can seem flimsy and hard to define. Nevertheless, three recent books have examined the role of imagination in the economy: Yuval-Noah Hararis Sapiens (2014), Joseph HenrichsThe Secret of Our Success(2015), and my own Why Information Grows (2015). The authors of these three books are all outsiders to economics: Harari is trained as a historian, Henrich is an anthropologist, and I am a physicist. One could see this as a limitation. But others may value the fact that people trained in wide-ranging disciplines are making an effort to contribute to economics.

In Sapiens, Harari examines the imagination-based origins of human institutions, from religions to corporations. This is an important topic, since institutions have been a difficult nut to crack (though many attempts have been made, including the research of Douglas North and the institutional economics of Ronald Coase and Oliver Williamson). Harari notes that shared beliefs play an important role in society because they facilitate cooperation among strangers. Take religion, one of his chief examples. People who believe in the same God share expectations about moral choices and agree on rituals and behaviors. God is, in an empirical sense, imaginary, but the concept of a deity serves a powerful coordination purpose nevertheless. Similarly, Harari sees institutions as shared imaginings that humans construct collectively, thanks to the inventive capacities of human languagean important feature differentiating human languages from animal communication systems. By creating common worlds through narratives and stories, we can coordinate our activities more effectively. In Hararis view, institutions were born during the cognitive revolution, some 70,000 years ago, and humans developed imaginative language and could begin sharing worldviews. Imagination is thus a precondition for the emergence of human institutions.

Hararis ideas resonate with Henrichs in The Secret of Our Success, which emphasizes that human success is not a simple result of our species superior intelligenceespecially since, in important ways, our intelligence isnt superior to that of other primates. Our success, rather, hinges on our ability to learn from others and on our ability to accumulate knowledge through generations. Our success isnt solely the result of individual intelligence but a consequence of collective forms of intelligence, powered by social learning. Humans, Henrich argues, accumulate cultural packages of adaptive behaviors. Groups with superior cultural packages, he explains, outcompete other groups, making social learning adaptive. But because cultural packages are hard to explain, their transmission usually involves mysterious or not fully understood rituals that people adopt: taboos, songs, and myths, for instance, which might be literally inaccurate but are evolutionarily useful because of the adaptive knowledge that they help convey. In Henrichs view, the institutions emphasized by Harari are adaptive when they aid in the intergenerational transmission of knowledge.

Henrich teaches us that our ability to imagine solutions to adaptive problems, or to understand why these solutions work, is individually very limited, and therefore has evolved to be tacitly collaborative. As a species, we have not historically relied on our individual ingenuity or rationality but on wisdom, the accumulation of ingenuity developed through generations and transmitted through rituals, some of which seem bizarrelike adding ashes to corn before you eat it, or narratives about why people should share meat after huntingbut have proved decisive for the survival of some groups. Once again, imagination is crucial, since it not only helps provide the narratives that perpetuate the ritual across generations but also because over long periods, imagination is what our species truly accumulates. The growth that preceded the modern pecuniary expansion of economies is that of accumulated wisdom and imaginationwhat some would call culture.

Hararis and Henrichs books contribute to our understanding of imagination in the context of human institutions and adaptive culture. Why Information Grows, on the other hand, focuses on the role of imagination in the context of products and economic growth. Economists have habitually considered products as widgets that people exchange to create value, or mathematically, as points in a continuum. But products are far from abstract; they have specific uses (have you tried brushing your teeth with a shoe?). In Why Information Grows, I develop a more granular theory of what products are and how our ability to make them shapes the economy.

Comparing the world of early hominids with our modern world can help us understand the economic relevance of imagination and products. The atoms available to cavemen were the same that we have today, but our world looks extremely different from theirs. What changed? Two things: the way in which those atoms are arranged; and our ability to arrange atoms. Products are not actually made of those atoms but from the physical order that they embody. The same plastic can be used to create a spoon or a comb, just as the same tree can be used to create four chairs or one table. The homes, cars, subways, and refrigerators that we associate with prosperity are made of physical order, begot first as imagination. I refer to that physical order as information and to our capacity to create physical order as computation. Economies are computers that not only calculate prices, as Friedrich Hayek would have said, but that also rearrange atoms to create products.

But why create products? Because, by embodying imagination in matter, we can communicate the practical uses of our knowledge. We live in a world where we constantly use products that we do not know how to make but that make our lives easier. We can communicate at long distances, fly across the world, and enjoy quality entertainment, not because we ourselves know how to manufacture planes, build global communication networks, or make movies but because other people do. And that is true for all of us, since most of the time, we are consuming things made by people who know things that we dont. By creating products, we multiply the number of people who can benefit from the knowledge and know-how embodied in only a few individuals. Products can communicate uses in ways that words cannot. They represent a different form of communication, essential to understanding economic growth. In this view, economic growth represents our ability to transform useful imagination into reality at scale.

Ultimately, then, a better conceptualization of the role of imagination in the economy involves thinking of imagination in the context of, first, shared beliefs that help us coordinate our activities with others; and, second, the embodied information that allows products to distribute the practical uses of knowledge and know-how.

Can we put these two ideas together? Since creating products is difficult, because making them requires more knowledge than what any single individual possesses, humans need to create networks to accumulate that knowledge and know-how. The creation of these networks is facilitated by the institutions and rituals described by Harari and Henrich but also by the products that we make, since many of these involve devices that augment our communication and transportation capacities. So by embodying imagination into the institutions that help us form cooperative networks, and by embodying imagination into the products that augment our capacity to interact, we expand the capacity of these networks and ignite economic growth. In fact, the diversity and sophistication of a countrys products accurately predict future economic growthcontrary to what neoclassical trade theory would predict, seeing products as epiphenomenal, rather than central to economic development.

Is there a future for this unwieldy, sprawling post-neoclassical field? I believe that there is. Of course, I myself feel part of it, so I might have a vested interest. Nonetheless, I believe that the field is valuable and that several recent developments confirm that it will have a place in our economic thinking.

First, economics is undergoing a generational change. Decades ago, heterodox views of economicsand the scholars advancing themwere excluded from the academic elite and the worlds most prestigious institutions. The most famous example of this marginalization was the ousting of Sam Bowles from Harvard in a highly contested tenure case in the early 1970s. Bowles, Herbert Gintis, and others packed their bags and moved to Amherst, where they started a successful program in heterodox economics that has produced decades of quality research. Bowles and Gintis, important pioneers of behavioral economics, were deeply interested in human behavior and on the conditions under which people cooperate. Also, they were interested in how people acquired preferences through social learning, since they were unhappy assuming utility functions as given.

Nearly 50 years later, things have dramatically changed. Now, behavioral economists are hot in the academic market, and every economics department wants to employ at least one. Most of these new behavioral economists, like Sendhil Mullainathan at Harvard or Dean Karlan at Yale, are relatively young. These Generation X thinkers are serving as models for a new generation of economists, now in graduate schools, who are more willing to challenge the neoclassical tradition. These new generations are looking for niches to make a contribution, and areas once excluded from the economics mainstream provide the most fertile territory for the establishment of a new camp.

This generational shift has also been strong in policy-oriented organizations like the World Bank, the OECD, and even the IMF. Decades ago, these organizations were almost exclusively neoclassical in orientation, but now they are also populated by nontraditional thinkers. The shift in these organizations is important because it means that post-neoclassical economists have leverage within the worlds leading policymaking organizations.

The diversity and sophistication of a countrys products accurately predict future economic growth.

The deepening maturation of post-neoclassical thinking has also made the field increasingly relevant. Behavioral economics doesnt just explore the quirkiness of human behavior; it also makes clear recommendations about how to nudge human behavior in (ideally) beneficial ways. The post-neoclassical toolbox goes far beyond this, however. Behavioral psychologists and economists have developed a formal understanding of how the framing of problems affects peoples decisions, even in situations that could be perceived as equivalent, at least from a neoclassical point of view. Too many case studies exist in which simple monetary incentives backfirefor example, the preschool in Israel that started charging parents who picked up their children late, only to see parents arriving even later.

The post-neoclassical approach has also become relevant in the context of innovation systems and regional economic diversification. For decades, as Ive noted, neoclassical economics has struggled to account for innovation, beyond mathematically abstracting it as an important secret sauce. Evolutionary economists, from Richard Nelson and Sidney Winter to Ron Boschma, Marianna Mazzucato, and yours truly, have developed empirically validated theories of the process of economic diversification showing that a regions productive structure is deeply affected by innovation policy. This literature, which views economic development as a form of collective learning rather than as the consequence of the accumulation of factors, has helped revive interest in some forms of industrial policy and encouraged the development of tools to assess the economic potential of countries and regions.

Finally, post-neoclassicalism also drew strength from the 2008 financial crisis, which encouraged criticism of the neoclassical tradition for not being more self-critical. Consider the abstract of this 2010 paper by Ricardo Caballero from MIT: The current core of macroeconomics . . . has become so mesmerized with its own internal logic that it has begun to confuse the precision it has achieved about its own world with the precision that it has about the real one. This is dangerous for both methodological and policy reasons. More recently, Paul Romer, now chief economist of the World Bank, made global ripples with a paper critiquing neoclassical macroeconomics.

Of course, neoclassical economists will not lose their place in history. After all, theirs has been a useful theory. But as economics continues to progress, the neoclassical tradition will need to become more comfortable sharing the spotlight with other theories that succeed where neoclassical theory fails. My bold prediction is that new historical figures will emerge in economics and that they will include people from the post-neoclassical field. These individuals might include those who bloomed at the economics fringe during the last generationpeople like Kahneman, Bowles, Mark Granovetter, Tversky, Ostrom, and Gintisbut also those who still have their best work ahead of them.

Csar A. Hidalgo is an associate professor at MIT, director of the Collective Learning group at the MIT Media Lab, and the author of Why Information Grows: The Evolution of Order, from Atoms to Economies.

Illustrations by Ryan Peltier

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Not Quite Rational Man - City Journal

UCLA researchers link genetics, brain morphology to autism, schizophrenia – Daily Bruin

UCLA researchers discovered that individuals with certain brain structures and genetics are at a higher risk of autism and schizophrenia.

The researchers found that certain chromosomal abnormalities can increase individuals risk of schizophrenia and autism. These findings could help explain the biology behind these neuropsychiatric disorders and help researchers understand their causes at a cellular level, said Carrie Bearden, the lead author of the study.

Bearden, a professor of psychiatry and biobehavioral sciences, found that children missing specific sections of genetic material on chromosome 22 are at greater risk for schizophrenia.

Bearden also found that children with 22q gene duplication are at greater risk for autism and learning delays but are at a lower risk for schizophrenia.

The genetic differences also result in different brain structures, and brain anatomy can be related to psychiatric disorders, Bearden said. After running MRI scans of 143 study participants, the researchers found that the children with 22q deletion had a smaller brain surface area but thicker gray matter, while people with 22q duplication had a larger brain surface area and thinner gray matter.

Bearden added that while these genetic brain differences alone do not cause schizophrenia and autism, they will help researchers understand these disorders. She said the research team will continue to study the different brain structures and see how the participants in the study change over time.

The next question is, How does brain anatomy and brain function relate to psychiatric outcomes? These findings provide a snapshot, Bearden said in a statement. (Our follow up studies) are the puzzle pieces that are next on our list to disentangle.

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UCLA researchers link genetics, brain morphology to autism, schizophrenia - Daily Bruin

Nebraska played a major role in the advancement of plant genetics and crop breeding – High Plains Journal

This story starts with Rollins A. Emerson, born in Upstate New York in 1873, who moved as a child to Nebraska, where his family homesteaded near Kearney. He obtained a bachelor of science degree from the Agricultural College at the University of Nebraska-Lincoln in 1895, with the eminent botanist Charles E. Bessey as his mentor.

Emerson worked in Washington, D.C., for several years as a horticultural editor with the U.S. Department of Agricultures Office of Experiment Stations before returning to Lincoln in 1899 as the horticulturalist with the Nebraska Experiment Station and professor and head of the Horticulture Department, where he began his distinguished career in genetic research, concentrating first on the common bean.

Emerson was one of the first American scientists to embrace the ideas of Gregor Mendel, also referred to as Mendelian genetics. These principles state that certain genetic traits are inherited or passed on to progeny from their parents, and were derived after carefully conducted experiments with garden peas.

After publishing his results in an obscure Austrian journal in 1866, Mendels work went unnoticed until 1900, when his publication was rediscovered independently by four scientists: Dutch botanist Hugo de Vries; German botanist and geneticist Carl Correns; Austrian agronomy graduate student Erich von Tschermak-Seysenegg; and American wheat breeder and economist William Jasper Spillman.

Emerson was awarded a Ph.D. in 1912 and became interested in corn research, moving to Cornell University in 1914 to head the Department of Plant Breeding. It was here over the next three decades that he achieved world renown as a pioneer corn geneticist. He eventually built a corn breeding and genetics dynasty, mentoring many brilliant young scientists who later became accomplished geneticists (as both researchers and teachers) in their own rights.

It is also very possible that Emerson might have become even more universally famous and recognized for his work had he been better-versed in the German language. Wayne F. Keim (another University of Nebraska and Cornell Plant Breeding alumnus) related a story to me that was told to him personally by Emerson.

Keim

Wayne Keim is the son of F. D. Keim, the namesake for Keim Hall, the building on East Campus now housing the Department of Agronomy and Horticulture. Although Emerson had retired before the elder Keim started graduate school at Cornell in 1947, he did meet and visit with Emerson on several occasions. On one of those encounters, Emerson informed Keim that he had seen Mendels paper on the landmark pea experiments in the late 1890s while still at Nebraska, but due to his lack of mastery of German, he was unable to fully understand the significance of Mendels paper published 35 years earlier.

Based on this conversation with Emerson, Keim then pondered: How close was Rollins A. Emerson and the University of Nebraska College of Agriculture to being the first discoverers rather than the three Europeans?

Keim grew up on a farm near Hardy, Nebraska. After graduating from Davenport High School, he attended Peru State Normal (now known as Peru State College), a school designed to train elementary- and secondary-school teachers.

He taught for several years in high schools in southeastern Nebraska before entering the College of Agriculture at the University of Nebraska, where he earned the Bachelor of Science degree in 1914. He completed a Master of Science degree in 1918, while also working as a full-time assistant in agronomy.

During his undergraduate years Keim encountered Emerson, prior to Emersons move to Cornell. Emerson stimulated his lifelong interest in genetics, and encouraged Keim to pursue a Ph.D. at Cornell University.

Because Keim was now a full-time member of the faculty and did not want to give up his position in Lincoln, he made use of annual leaves and sabbaticals to complete the Ph.D. gradually, finishing it in 1927. All of his research and writing of the dissertation was done in Lincoln.

By all accounts, Keim was an outstanding teacher, always eager to identify outstanding students and assign them special tasks assisting him like grading papers and tests, or conducting research projects and greenhouse work, in the effort to spur their interest in genetics and agriculture at the academic level. His recruiting methods were often biased toward Cornell and their plant breeding program.

Keims influence was so strong that he continued advising many of his protgs throughout their careers wherever they ended up. Many went on to play key roles nationally as teachers, researchers, administrators, and in industry positions.

Two of Keims more prominent undergraduate mentees were George F. Sprague and George W. Beadle. Both additionally attended and completed Ph.D.s with Emerson at Cornell in the plant breeding department, Sprague in 1930 and Beadle in 1931.

Sprague and Beadle

Sprague went on to a long, distinguished and internationally recognized career as a corn breeder and geneticist with both the U.S. Department of Agriculture and Iowa State University. Many students he trained afterward listed him as their primary influence and mentor. He was additionally elected into the National Academy of Sciences.

After the Ph.D. and several postdoctoral positions, Beadle went on to a brilliant career as a geneticist on the faculty of three institutions (Harvard, California Institute of Technology, and Stanford) before serving as both Chancellor and President of the University of Chicago.

While at Stanford, he teamed with the biochemist E. L. Tatum investigating biochemical genetics using the bread mold fungus Neurospora crassa as the model organism. In this system, they discovered the role of certain genes in producing enzymes that regulate biochemical pathways in cells, referred to as the one gene-one enzyme theory, for which they were awarded the Nobel Prize in Physiology or Medicine in 1958.

Beadle was additionally honored in 1994 when the University of Nebraskas Center for Biotechnology was named after him (George W. Beadle Center for Genetics and Biomaterials Research).

Srb and Keim

Adrian Srb, son of Frank Keims UNL agricultural faculty colleague Jerome Srb, was inspired to pursue the Ph.D. after completing his bachelors degree at Nebraska. He attended Stanford, working with Beadle in genetics. After completion of his doctorate, he took a job at Cornell in the plant breeding department.

This story comes full circle with F.D. Keims son, Wayne. After completing his fathers course in genetics (and a B.S. in agronomy), he was also encouraged by his father to attend Cornell and work with Srb.

Wayne related that Adrian Srb was the individual responsible for him to seek a career in plant breeding, with an emphasis on teaching genetics to undergraduate students. Keim then spent 45 years at Purdue University and Colorado State University before retiring in 1992. Quite an impressive academic pedigree originally initiated in Nebraska by Rollins A. Emerson.

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Nebraska played a major role in the advancement of plant genetics and crop breeding - High Plains Journal

Intelligence definitively linked to genetics: Does this open doors to racism? – Genetic Literacy Project

Your intelligence is partly due to hard work, nutrition, and education. But you can also thank (or blame) your genes for your mental abilities.

Decades of work on twin studies suggest that genes account for roughly half of variations in IQ seen across a population. And a meta-analysis published [recently] in Nature on nearly 80,000 people has identified 40 specific genes that affect intelligence. The one study more than quadrupled the number of genes scientists know of that shape intelligence, bringing the total number to 52.

[However,] there are hundreds of genes that play a role in intelligence [that] are yet to be discovered.

But plenty of people are anxious about scientists heading down that path, and what will happen when they reach the end of itIt presents an uncompromising but disquieting truth: That some people will just never be as intelligent as others, simply because of their genetics.

In an editorial, the authors of the study acknowledge the controversyand say many concerns derive from racist eugenic practices of the past. But the genetics of intelligence is complex and subtleand simply doesnt support prejudiced theories of racial superiority. In fact, they argue, better understanding the genetics underlying intelligence will disprove racist theories of eugenicists.

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion, and analysis. Read full, original post:A massive new study lays out the map of our genetic intelligence

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Intelligence definitively linked to genetics: Does this open doors to racism? - Genetic Literacy Project

Kindergarten eggscited over hatching – HeraldandChronicle.com

Terri Fisher saves the best lessons for the end of the school year. At least she thinks so. And her kindergarten students clearly agree. Last week, Fisher's classroom at Conowingo Elementary became home to three eggs and an incubator. This week, if the timing is right, one or all of those eggs will hatch. "It's the most exciting part of the year. It's something that might hatch. Maybe they'll all hatch and hopefully, we can capture that moment," said Fisher.

Through Maryland Extension and grant funds, Cecil County 4-H is providing an incubation and embryology project at all the local elementary schools and at a few community sites. For chickens, the incubation period takes about three weeks until they hatch. Fisher's classroom and others throughout the county receive the pre-incubated eggs two weeks into the incubation period. Students and teachers care for and monitor the eggs. After hatching, the newborn chicks remain in classrooms for observation for up to three weeks. Extension staffer 4-H program assistant Victoria Stone provides support in the classrooms. She teaches practical lessons in the classrooms three times during the embryology unit. Students learn about feeding, bedding, and warming the peeps. Stone explained that about 60 classrooms are receiving these lessons throughout the county. "I get excited. This is real life stuff," said Fisher. She and her family have chickens at home. The embryology unit was the catalyst for that. She adopted chickens after they were in her classroom. "The chickens were motivation for my son to finish his Eagle Scout project," said Fisher. And at school, the students are ready for the responsibility of hatching and caring for baby chicks. "They take it seriously. They observe them and ask questions. They remind me that the chicks need food and water on weekends," said Fisher. In addition to the life cycle education, Fisher has also been able to incorporate the eggs/chicks into other areas of study. Counting down the days until the chicks arrive helped with numbers. They also learned about the different parts of an egg. They also speculated about the different varieties of chicks that could come from the eggs in the classroom. Student Nataleigh Ruisard has a bird's eye view. "The eggs are going to hatch. I sit next to it (the incubator)," she said. Her fellow kindergartner, Tripp Antognoli, is so involved with embryology that he dreams about it. "I dreamed a blue chick came out of one of the eggs," he said. And that is possible. The students have determined that one of the eggs could become a Delaware blue hen. "This is so rewarding. It's been a highlight of the year. This is my 30th year of teaching and it engages them so much. I wish I had more time with the chicks," said Fisher.

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Kindergarten eggscited over hatching - HeraldandChronicle.com

Did you go abroad for fertility treatment? Tell us why | Society | The … – The Guardian

Its believed a growing number of people go to countries such as Spain for fertility treatments. Photograph: ZEPHYR/Getty Images/Brand X

An investigation has been launched into the number of people going abroad for IVF treatment and coming back pregnant with twins or triplets.

Doctors fear that hundreds of women are returning to Britain with multiple pregnancies after getting treatment abroad, putting pressure on the NHS. Twin or triplet pregnancies are more expensive due to the need for additional scans and longer hospital stays. According to the Human Fertility and Embryology Authority, multiple births carry the greatest health risk in fertility treatment. More than 90% of triplets have low birth weights, putting them at risk of health problems.

The number of multiple births fell in the UK after 2008 when it was decided that only a single embryo would be implanted at a time to reduce risky pregnancies. But foreign clinics do not always have the same rules and guidelines in place.

The trend of people going abroad treatment comes as the NHS rations IVF to reduce costs, a move thats been condemned by critics. Its believed a growing number of people go to countries such as Spain for fertility treatments because they are cheaper and the waiting list for donated eggs is shorter.

We want to hear from people who have gone abroad for fertility treatments. Why did you go? Have you come back and are due to have twins or triplets? What do you think of the UK IVF industry? Is it too expensive? We also want to hear from those treating patients, tell us about your experiences as someone who works in the industry. Share your views and thoughts.

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Did you go abroad for fertility treatment? Tell us why | Society | The ... - The Guardian

Key process for cell division revealed in molecular analysis – Phys.org – Phys.Org

June 1, 2017

Researchers have discovered important details of a vital process that enables cells to divide correctly into two.

Their findings shed light on the molecular processes that determine how and when key proteins combine, to help create a site required for accurate DNA separation over generations.

Researchers from the University of Edinburgh used biophysical and cell biology techniques to better understand the assembly of a key set of proteins known as Mis18.

Their study offers insights as to how the Mis18 protein complex controls the accumulation of another protein, known as CENP-A.

The CENP-A collects at a site where the dividing cell's DNA - which is packaged into a pair of chromosomes - connects and then divides into two cells.

By studying the molecular mass of the constituent Mis18 proteins as they combined, researchers were able to determine how many proteins of each type assembled to form a functional Mis18 complex.

They also found how a further protein, known as Cdk1, controls the timing of Mis18 assembly, by temporarily modifying one of the proteins involved to prevent it from binding the others.

The study, funded by the Wellcome Trust, was published in EMBO reports.

Dr Jeyaprakash Arulanandam, of the University of Edinburgh's School of Biological Sciences, who led the study, said: "These findings provide valuable insights into how cells help preserve the site essential for equal distribution of their DNA when they divide, and how the timing of this process is tied to the cell cycle."

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Passing skills down through the generations, previously thought to be unique to humanity, has been discovered in chimpanzees.

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