Konica Minolta, With Eye on Health Care, Nears Deal for U.S. … – New York Times

An announcement is expected on Thursday, and the companies hope to complete the transaction by the end of the year. Ambry Genetics declined to comment.

The Japanese government is helping to drive the diversification efforts. A state-backed investment fund, the Innovation Network Corporation of Japan, is teaming up with Konica Minolta in the Ambry acquisition. According to the people familiar with the deal, Konica Minolta would take a 60 percent share in Ambry, with the rest to be acquired by the fund.

Ambry, which is privately held, would retain its current leadership, these people said. The management team includes the company founder and chairman, Charles L. M. Dunlop, who has said his own experience with prostate cancer now in remission influenced his decision to make public anonymized information from Ambrys database.

Pooling data from many people is considered crucial to finding genetic elements that contribute to illnesses.

For Konica Minolta, the acquisition would confirm the acceleration of efforts to diversify beyond photocopiers and printers, areas where revenue and profit have been shrinking.

The Japanese company has identified health care, and cancer screening in particular, as a possible mainstay of business. It has been developing its own cancer-detecting technology using light-emitting nanoparticles to mark proteins that are drawn to cancer cells.

Other Japanese businesses have tried similar expansions. Fujifilm, for instance which, like Konica Minolta, built a name decades ago in photography has established a profitable health care and cosmetics division, helping it survive the end of the analog film era.

Other Japanese groups health care ventures have been less successful, however.

Follow Jonathan Soble on Twitter @jonathan_soble.

Chad Bray contributed reporting from London.

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Konica Minolta, With Eye on Health Care, Nears Deal for U.S. ... - New York Times

Genetics may lie at the heart of crop yield limitation – Phys.org – Phys.Org

July 5, 2017 Comparison of growth differences in wild-type (left) and growth-repressor mutant (right) Arabidopsis plants. Credit: Dr Nick Pullen

You might think that plants grow according to how much nutrition, water and sunlight they are exposed to, but new research by Dr Nick Pullen and a team from the John Innes Centre, UK shows that the plant's own genetics may be the real limiting factor.

"This could have potentially big implications for the agricultural industry," says Dr Pullen, "Our model plant is in the same family as cabbages, so it's easy to imagine creating giant cabbages or growing them to the desired market size faster than at present."

It was previously assumed that plant growth was generally resource-limited, meaning that plants would only grow as large and fast as they could photosynthesise. However, Dr Pullen and his team present evidence that plant growth is actually "sink-limited", meaning that genetic regulation and cell division rates have a much bigger role in controlling plant growth than previously thought: "We are proposing that plant growth is not physically limited by Net Primary Productivity (NPP) or the environment, but instead is limited genetically in response to these signals to ensure they do not become limiting."

By genetically altering the growth repressors in Arabidopsis, Dr Pullen and his team were able to create mutant strains. They identified the metabolic rates of the different plant strains by measuring rates of photosynthesis and respiration, as well as comparing the size and weight of the plants to monitor differences in physical growth.

Dr Pullen and the team also grew the mutant plant strains at different temperatures to see if this changed their results: "When grown at different temperatures we still find a difference in size of our plants between wildtype and the mutants. This suggests our results should be applicable in different climates."

The impact of these results is wide-reaching, and Dr Pullen suggests that it may even change how we think about global climate data: "Climate models need to incorporate genetic elements because at present most do not, and their predictions would be much improved with a better understanding of plant carbon demand."

Explore further: Revealed: New step in plant mastermind hormone's pathway

Plants are stationary. This means that the way they grow must be highly internally regulated to use the surrounding resources in the most-advantageous way possible.

Garden and potted plants with white spots on their leaves are so popular that they are specially selected for this feature. An international research team has now identified a new mutation in the plant Lotus japonicus which ...

Researchers have discovered a new gene that enables plants to regulate their growth in different temperatures.

Scientists have identified a new mutant plant that accumulates excessive amounts of starch, which could help to boost crop yields and increase the productivity of plants grown for biofuels.

New research from an Iowa State University scientist identifies a genetic mechanism that governs growth and drought tolerance in plants, a development that could lead to better performing traits in crops.

Because plants cannot relocate when resources become scarce, they need to efficiently regulate their growth by responding to environmental cues. Drought is the most important cause of reduced plant growth and crop yield, ...

Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have undertaken the first ever comprehensive analysis of autophagy in a living animal during aging. "Autophagy," which means "self-eating" based on its ...

When exposed to potential predators as an embryo, the invasive American bullfrog becomes harder to kill when it becomes a tadpole, according to a new study by Oregon State University researchers.

Moving genes about could help cells to respond to change according to scientists at the Babraham Institute in Cambridge, UK and the Weizmann Institute, Israel. Changing the location of a gene within a cell alters its activity. ...

Even though malaria still kills one child every minute, the vast majority of those infected still survive, with roughly 200 million new infections every year. A new study has shown that the infectious agent responsible for ...

Muscles require energy to perform all of the movements that we do in a day, and now, for the first time, researchers at the Texas A&M College of Medicine have shown how muscles "request" more energy from fat storage tissues ...

Scientists at Johns Hopkins, Rutgers, the University of Trento in Italy, and Harvard Medical School report they have developed a new molecular technique called LASSO cloning, which can be used to isolate thousands of long ...

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Genetics may lie at the heart of crop yield limitation - Phys.org - Phys.Org

Genetics of Harry Potter: What wizardry can tell us about our DNA – Genetic Literacy Project

[In the world of Harry Potter,] magic appears to follow some of the same rules as other traits that are inherited, but what could be the genetic factors that explain why someone is born a witch or a wizard or without any magical ability at all?

A roomful of people at Future Con got a crash course in wizarding DNA and the basic workings of genetics on June 17, at a talk hosted by Eric Spana, an assistant professor in the Department of Biology at Duke University, in North Carolina.

Eric Spana describes wizard DNA at the Future Con panel, Harry Potter and the Genetics of Wizarding. Credit: M. Weisberger/Live Science

Is the wizarding gene recessive? Hagrid, the half-giant-half-wizard groundskeeper at Hogwarts, proves that it isnt, according to Spana. Giants have no magical ability, and Hagrid was born to a giant mother and a wizard father. For him to be born a wizard with only one copy of the wizard gene in his DNA, magical ability would have to be a dominant trait, said Spana.

If the wizarding gene is working correctly, it makes a certain type of protein. The phenotypeis magical ability. But if theres amutation in that gene Spana suggested calling it the SQUIB mutation a different type of protein turns the magic gene off. If one parents DNA carries a copy of the SQUIB mutation, it can turn off the wizarding protein, which cancels a childs ability to do magic.

We do this in fruit flies all the time, Spana said, referring to manipulation of heritable traits in general.

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion, and analysis. Read full, original post:Genetics of Wizardry: Were Harry Potters Magical Powers Written in His DNA?

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Genetics of Harry Potter: What wizardry can tell us about our DNA - Genetic Literacy Project

Hendrix Genetics Plans Hatchery-Egg Production Facility In Beresford, South Dakota – Area Development Online

News Items

According to state officials the company will directly distribute quality Hybrid commercial poults to growers. The investment plan includes new hatcheries, egg production facilities, a modern transportation fleet, and the hiring of skilled workforce needed to support these areas of operations.

This new hatchery allows us to continue to deliver on our core focus of providing top quality genetics that match the needs of the market and our customers. This is a critical component of our plan to modernize the commercial turkey distribution infrastructure in the USA, said Dave Libertini, Managing Director.

South Dakota is consistently recognized as a top state in the nation to do business. Hendrix Genetics made the right decision to expand to our state. Theyll find a skilled and productive workforce in the Beresford region. Were proud to call Hendrix Genetics South Dakotas newest corporate citizen, said Governor Dennis Daugaard.

The proposed turkey hatchery in Beresford will have capacity for 35 million hatching eggs. The new hatchery, plus the capacity within the aligned partners, offers the capability of hatching 60 million eggs for the commercial market, officials said. The facility will be outfitted with cutting-edge equipment, featuring Petersime incubators, to ensure the highest biosecurity and poult quality.

Adjacent to Interstate 29 between Sioux Falls and Sioux City, Beresford is well connected to the interstate system to transport day-old poults to the USA market, state officials said. In addition, access to a skilled workforce and the support of the local community were elements of the decision process for Hendrix Genetics.

We are so fortunate Hendrix Genetics picked Beresford for its new hatchery. I could not be more pleased and excited to have a company of this caliber joining our community. When you consider that we are getting a quality company, 50+ jobs, more people living in our town and more kids in our great school system, this really becomes a win-win for the city of Beresford, said Mayor Jim Fedderson, City of Beresford.

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Hendrix Genetics Plans Hatchery-Egg Production Facility In Beresford, South Dakota - Area Development Online

Interleukin Genetics slashes workforce, explores options – BioPharma Dive

Dive Brief:

Interleukin Genetics attempted to restructure its debts back in April, entering into a rejiggered agreement with Horizon Technology Finance which deferred the principal amount owed to the lender on April 1, May 1 and June 1. The deferral could have continued each month through September, but the borrower had to lock down by June 15 a "clinical services agreement" that had the approval of Horizon Technology Finance.

That didn't happen, and now Interleukin Genetics is doing whatever it can to gain capital.

"While this decision was extremely difficult, it is important to preserve capital as we assess our options," Interleukin Genetics CEO Mark Carbeau said in a July 3 statement. The company did not immediately respond to BioPharma Dive request for comment.

Interleukin Genetics also said in the statement it had about $925,000 in cash on hand as of June 30. Due to the strategic evaluation, its second quarter financial filings with the Securities and Exchange Commission will be coming in late.

Horizon Technology Finance initially loaned $5 million to the borrower back in late 2014. The parties agreed that Interleukin Genetics would repay the loan over 45 months, with the first 15 months being only interest payments and the latter 30 being equal payments of the total principal plus interest. The revamped agreement from earlier this year offered Interleukin Genetics a few months of deferred payments in exchange for an estimated 5.5 million to 11 million shares of the company's common stock.

Even if the borrower had secured a clinical services partnership and been able to keep the payment deferrals going a few more months, it has had trouble generating revenue.

Interleukin Genetics garnered nearly $200,000 in total revenue during the first quarter, down from almost $961,000 during the same period in 2016, which the company attributed to a decline in contracted research projects. A $2.3 million loss from operational costs led the company to have a net loss of $2.5 million for the first three months of 2017.

Moving forward, the company expects its main assets will be its Clinical Laboratory Improvement Amendments-certified testing and the intellectual property for its diagnostic programs, including Ilustra and the Inherent Health brand. It also expects the current restructuring efforts will cost $245,000.

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Interleukin Genetics slashes workforce, explores options - BioPharma Dive

How a few drops of blood led to a breakthrough in immunology – Medical Xpress

July 5, 2017 The image shows a lymph node in which we see normal T cells (in red) and Treg cells regulated by the FOXP3 gene (in green). Lymph nodes are small glands that are part of the lymph system which is important for body's defense system against diseases. Technique used: Confocal microscopy Credit: Ciriaco Piccirillo, Research Institute of the McGill University Health Centre

Scientists from the Research Institute of the McGill University Health Centre (RI-MUHC) may have cracked the code to understanding the function of special cells called regulatory T Cells. Treg cells, as they are often known, control and regulate our immune system to prevent excessive reactions. The findings, published in Science Immunology, could have a major impact in our understanding and treatment of all autoimmune diseases and most chronic inflammatory diseases such as arthritis, Crohn's disease as well as broader conditions such as asthma, allergies and cancer.

Researchers made this discovery by investigating a rare human mutation in a gene called FOXP3. Although the importance of the FOXP3 gene in the proper function of Treg cells has been well documented, its mechanisms were still not fully understood by scientists.

"We discovered that this mutation in the FOXP3 gene affects the Treg cell's ability to dampen the immune response, which results in the immune system overreacting and causing inflammation," explains the study's lead author, Dr. Ciriaco Piccirillo, immunologist and senior scientist in the Infectious Diseases and Immunity in the Global Health Program at the RI-MUHC, and a professor of Immunology at McGill University. "This discovery gives us key insights on how Treg cells are born and how they can be regulated."

Thanks to an international collaboration and cutting-edge technology from the Immunophenotyping Platform at the RI-MUHC, the team was able to make their discovery using only a few drops of blood from a five-week-old newborn boy who died in 2009 from a rare and often fatal inherited genetic immune disorder called IPEX. In the past 40 years, fewer than 200 cases of IPEX have been identified worldwide. Over 60 different mutations of the FOXP3 gene are known to cause IPEX and believed to result in non-functional Treg Cells.

"What was unique about this case of IPEX was that the patient's Treg cells were fully functional apart from one crucial element: its ability to shut down the inflammatory response," says Dr. Piccirillo.

"Understanding this specific mutation has allowed us to shed light on how many milder forms of chronic inflammatory diseases or autoimmune diseases could be linked to alterations in FOXP3 functions," adds the study's first author, Khalid Bin Dhuban, a postdoctoral fellow in Dr. Piccirillo's laboratory.

From fundamental biology to clinical treatment

Dr. Piccirillo and his colleagues have already developed a molecule that could restore the Treg cells' ability to control the immune system for patients with the same rare mutation. The drug has been tested in animal models and the researchers are hopeful they can also develop similar drugs that will apply for other conditions where Treg cells are known to be slightly defective such as arthritis, type I diabetes, multiple sclerosis and lupus.

"Currently, we have to shut down the whole immune system with aggressive suppressive therapies in various autoimmune and inflammatory diseases," explains Dr. Piccirillo. Our goal is to increase the activity of these Treg cells in certain settings, such as autoimmune diseases, but we want to turn it down in other settings, such as cancer. With this discovery, we are taking a big step in the right direction."

Dr. Ciriaco Piccirillo is also the director of the Centre of Excellence in Translational Immunology (CETI), a newly established research coalition based at the Research Institute of the MUHC that fosters linkages among biomedical investigators and clinicians for interdisciplinary immunology research focused on the understanding and treatment of immune-based diseases.

Explore further: Preventing too much immunity

More information: Suppression by human FOXP3+ regulatory T cells requires FOXP3-TIP60 interactions, Science Immunology 16 Jun 2017: Vol. 2, Issue 12, eaai9297 , DOI: 10.1126/sciimmunol.aai9297 , http://immunology.sciencemag.org/content/2/12/eaai9297

An immune-related protein deployed between neighboring cells in Drosophila plays an essential role in the cell degradation process known as autophagy, according to new research by Eric H. Baehrecke, PhD, at UMass Medical ...

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How a few drops of blood led to a breakthrough in immunology - Medical Xpress

Sun Pharma agrees manufacturing deal for immunology candidate – The Pharma Letter (registration)

India's largest drugmaker Sun Pharmaceutical has entered into a manufacturing agreement with South Koreas

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Sun Pharma agrees manufacturing deal for immunology candidate - The Pharma Letter (registration)

Neuroscience < University of Chicago Catalog

Contacts | Program of Study | Declaring the Major | General Education | The Major | Grading | Summary of Requirements for the Major in Neuroscience | Honors | Minor Options | Courses

Department Website: http://neuroscience.uchicago.edu/undergraduate

Neuroscience is the study of neurons and neural systems and their outputs: sensation, perception, homeostasis, and behavior. Neural function is investigated at the levels of molecules, cells, circuits, organisms, and species, making neuroscience inherently multidisciplinary. In addition to established neuroscience career paths in academia, medicine, and the pharmaceutical industry, new careers for students of neuroscience are emerging in economics, software development, and other fields requiring "big data" analysis or a mechanistic understanding of how humans think. The course of study in the undergraduate major in neuroscience provides students with the background and skills appropriate for these diverse careers.

The University of Chicago offers a bachelor of arts (BA) degree and a bachelor of science (BS) degree in Neuroscience. The Neuroscience major is designed to accommodate students with the range of scientific variety that one finds at the professional level of neuroscience, including physics, chemistry, computer science, engineering, mathematics, biology, psychology, and medicine. Neuroscience faculty at the University of Chicago have expertise in all of these areas and are distributed across the Biological Sciences, Social Sciences, and Physical Sciences Divisions. Majoring students have the opportunity to take a broad range of courses or to specialize in a particular area.

Students who wish to major in Neuroscience should declare the major in their second year.

(Because the Neuroscience major was introduced in the 201617 academic year, the Class of 2020 and subsequent classes can design a plan of study in Neuroscience from their first year. Students in the Classes of 2018 and 2019 may also be able to major in Neuroscience, depending on the courses they have already taken, although there is no way to guarantee this. Students in these classes should consult with their College advisers to see if majoring in Neuroscience is feasible.)

Students majoring in Neuroscience typically begin their general education requirement in the Biological Sciences with BIOS20186 Fundamentals of Cell and Molecular Biology. Attaining a proper grounding in cell biology is essential before delving into neuroscience as a discipline. To complete the requirement, students may choose to take one of the following: BIOS20150 How Can We Understand the Biosphere?, BIOS20151 Introduction to Quantitative Modeling in Biology (Basic), BIOS20152 Introduction to Quantitative Modeling in Biology (Advanced), BIOS20187 Fundamentals of Genetics, BIOS20188 Fundamentals of Physiology, or BIOS20191 Integrative Physiology. (Note: The general education requirement for the NSCI major can be fulfilled by courses in the Biology Fundamentals Sequences [20186-20190] without the Biological Sciences prerequisites [BIOS 20150-20151/20152] unless a student pursues a double major in Biological Sciences. Students who choose this path will be expected to possess the competency in mathematical modeling of biological phenomena covered in BIOS 20151 or BIOS 20152.)

Two alternative paths to fulfilling the General Education requirements exist. 1) Neuroscience majors may petition to take the Pre-Med Sequence for Non-Biology majors. In this case, BIOS20170 Microbial and Human Cell Biology and BIOS20171 Human Genetics and Developmental Biology will satisfy the core. (Note that BIOS 20171 must be taken concurrently with BIOS20172 Mathematical Modeling for Pre-Med Students .) 2) A score of 4 or 5 on the AP Biology exam allows students to enter the Advanced Biology sequence in the Autumn of their first year. This three-quarter, lab-intensive sequence is for students with a strong background in research. Upon completion of the sequence students are awarded two credits, which satisfy the general education requirement in Biological Sciences.

The basic degree in Neuroscience is the BA, for which requirements are described below. A BS is awarded to students who complete an additional three quarters of Neuroscience electives, which must include one to three quarters of faculty-supervised research (scholarly or experimental) resulting in a written thesis (see Requirements for the Bachelor of Science Degree in Neuroscience below).

The major curriculum includes nine required Neuroscience courses, which provide a comprehensive overview of the field. The BA requires another 700 units of elective courses, which must be selected from the list below. Electives can be chosen for a broad exposure or tailored for depth in a particular area, such as cellular/molecular, systems, cognitive, and computational neuroscience and machine learning.

Students must have their program of elective courses approved by the office of the director of undergraduate studies. The Student Elective Approval Form should be filled out by the end of the third year and submitted to the Neuroscience major director of undergraduate studies for approval at neuromajor@uchicago.edu.

While it is possible to complete a double major in Neuroscience and another program, this is not encouraged. Neuroscience majors are generally better suited to achieving breadth through a combination of courses that provides the desired expertise in neuroscience and carefully selected courses outside of neuroscience.

Students can earn a BS in Neuroscience by completing three quarters of Neuroscience elective courses over and above the BA requirements, which must include one to three quarters of faculty-supervised research that results in a written thesis (NSCI29100, NSCI29101, NSCI29102 Neuroscience Thesis Research). The additional courses and the thesis work require approval by the office of the director of undergraduate studies and the thesis advisor. The thesis may be either research-based or literature-based.

All courses used to satisfy prerequisites and requirements must be taken for quality grades. Students must pass all required courses with an average GPA of 2.0 or higher to continue in the program.

To obtain honors in Neuroscience, students must have a minimum cumulative GPA (3.25) at the point of entering the honors track, no later than the end of the third year. Entry into the honors track must be approved by the director of undergraduate studies. Students must do experimental research for three quarters and submit a thesis (NSCI29200, NSCI29201, NSCI29202 Neuroscience Honors Thesis Research). As part of the research course work, honors students participate in regular group meetings in which they share their research with each other and supervising faculty, and receive guidance on formulating testable hypotheses, experimental design, report writing, and oral presentations. They also receive training in the responsible conduct of research. Experimental research may not be credited toward honors in more than one major.

A minor in Neuroscience is not offered. The College offers a minor program in Computational Neuroscience, and students majoring in Biological Sciences have the option of completing a Specialization in Neuroscience.

NSCI00292. Neuroscience Honors Thesis Research. 100 Units.

Research Thesis and Seminar

Instructor(s): Elizabeth GroveTerms Offered: Summer Prerequisite(s): Acceptance into the Neuroscience Honors Program

NSCI20100. Neuroscience Laboratory. 100 Units.

This course has three components in series, representing (1) molecular neuroscience, (2) cellular electrophysiology, and (3) computation and psychophysics. The course meets one afternoon each week for four hours of laboratory time, including a didactic introduction. Students will be graded on their laboratory reports.

Instructor(s): J. Maunsell; E. Heckscher; C. Hansel; M. McNultyTerms Offered: Winter Note(s): This course will be offered in the 201718 academic year and each year thereafter.

NSCI20110. Fundamental Neuroscience. 100 Units.

This course is a rigorous introduction to the study of neurons, nervous systems and brains. The systems anatomy and physiology of the vertebrate brain will be covered in depth. Common features of neural circuits, such as those subserving the stretch reflex, will be examined. The biology of brain evolution and development will be introduced. A highlight of this course will be student dissections of sheep brains and the laboratory presentation of human brain dissections by the instructors.

Instructor(s): C. Ragsdale, P. Mason Terms Offered: Autumn Prerequisite(s): At least two quarters of Biological Sciences instruction (including courses taken concurrently) or consent of instructor. Equivalent Course(s): BIOS 24110

NSCI20120. Cellular Neuroscience. 100 Units.

This course describes the cellular and subcellular properties of neurons, including passive and active electrophysiological properties, and their synaptic interactions. Readings are assigned from a general neuroscience textbook.

Instructor(s): R. A. Eatock, W. Wei, StaffTerms Offered: Winter Prerequisite(s): NSCI 20110, along with completion of MATH 13100, or MATH 15100, or MATH 16100 Equivalent Course(s): BIOS 24120

NSCI20130. Systems Neurobiology. 100 Units.

This course covers vertebrate and invertebrate systems neuroscience with a focus on the anatomy, physiology, and development of sensory and motor control systems. The neural bases of form and motion perception, locomotion, memory, and other forms of neural plasticity are examined in detail. We also discuss clinical aspects of neurological disorders.

Instructor(s): D. Freedman, Staff Terms Offered: Spring Prerequisite(s): NSCI 20110, and NSCI 20120 or consent of instructor Equivalent Course(s): BIOS 24130

NSCI20140. Sensation and Perception. 100 Units.

What we see and hear depends on energy that enters the eyes and ears, but what we actually experienceperceptionfollows from human neural responses. This course focuses on visual and auditory phenomena, including basic percepts (for example, acuity, brightness, color, loudness, pitch) and also more complex percepts such as movement and object recognition. Biological underpinnings of perception are an integral part of the course.

Instructor(s): K. LedouxTerms Offered: Winter Equivalent Course(s): PSYC 20700

NSCI29100. Neuroscience Thesis Research. 100 Units.

Scholar or Research Thesis.

Instructor(s): StaffTerms Offered: Autumn,Spring,Summer,Winter Prerequisite(s): By consent of instructor and approval of major director.

NSCI29101. Neuroscience Thesis Research. 100 Units.

Scholar or Research Thesis.

Instructor(s): StaffTerms Offered: Autumn,Spring,Summer,Winter Prerequisite(s): NSCI 29100, and consent of instructor, and approval of major director.

NSCI29102. Neuroscience Thesis Research. 100 Units.

Scholar or Research Thesis.

Instructor(s): StaffTerms Offered: Autumn,Spring,Summer,Winter Prerequisite(s): NSCI 29100, and consent of instructor, and approval of major director.

NSCI29200. Neuroscience Honors Thesis Research. 100 Units.

Research Thesis and Seminar.

Instructor(s): StaffTerms Offered: Autumn,Spring,Summer,Winter Prerequisite(s): By consent of instructor and approval of major director. Open to Neuroscience majors who are candidates for honors in Neuroscience.

NSCI29201. Neuroscience Honors Thesis Research. 100 Units.

Research Thesis and Seminar.

Instructor(s): StaffTerms Offered: Autumn,Spring,Summer,Winter Prerequisite(s): NSCI 29200, and consent of instructor, and approval of major director. Open to Neuroscience majors who are candidates for honors in Neuroscience.

NSCI29202. Neuroscience Honors Thesis Research. 100 Units.

Research Thesis and Seminar.

Instructor(s): StaffTerms Offered: Autumn,Spring,Summer,Winter Prerequisite(s): NSCI 20201, and consent of instructor, and approval of major director. Open to Neuroscience majors who are candidates for honors in Neuroscience.

Link:
Neuroscience < University of Chicago Catalog

I Tried a Mindfulness App to Fight My App Addiction – Organic Authority

iStock/Georgijevic

Technology can be addictive. I got to a point where I felt like I needed to check my phone even though Id only checked it five minutes before.While I knew that didnt make sense, I still checked it. I was frustrated with myself. But what I didnt know was that the feeling I was having was well-designed and predictable. Tech companies pay for us to develop app addiction.

While Dopamine Labs typically designs apps to be addictive, the company also created an app called Space Because You Need a Breatherto combat app addiction. This past week, I gave it a shot and talked to Matt Mayberry, Dopamine Labs head of business development, about how Space works.

Dopamine Labs uses artificial intelligence and neuroscience to help tech companies design apps and software. Essentially, the goal is to make you want to use technology as often as possible. The API (an app-intelligence program) gives users the perfect burst of dopamine to keep them hooked, says Mayberry. Dopamine Labs co-founder Dr. Combs holds a PhD in neuroscience.

One example of how Dopamine Labs API works is Instagram likes. When you post a photo on Instagram, in reality, most of your likes come in at about the same time. But Instagram is designed to hold back likes. The app only shows them to you when youve been away from Instagram a while. This way, you keep coming back for more.

Its mischievous, says Mayberry, but its also brilliant.

One night, the team at Dopamine Labs began to discuss what it would be like if someone built an anti-dopamine. In other words, what would happen if the team built an app that stopped the addictive dopamine rush? What they came up with was Space Because You Need a Breather, an app that fights app addiction.

Space reverses the work Dopamine Labs typically does, re-wiring your instant gratification sensors to not go off every time you check an app. Anti-dopamine is simple: Instead of giving you instant gratification when you check an app, it makes you wait for a brief pause. Just this moment of waiting decreases the addictive effect of instant gratification you typically get when you see another flood of likes. In effect, instant gratification is being replaced with a moment of mindfulness.

When I got Space Because You Need a Breather, the app allowed me to choose certain apps or websites I wanted space from. I chose my email, Facebook, and Instagram. Then, every time I clicked one of those apps, a screen of deep space popped up and asked me to take 1 deep breath beforeI started.

Thats literally all the app does. It makes you wait a little longer than you typically would to use an app. Because youre forced to wait for one deep breath (sometimes more), your instant gratification sensors dont get the happy rush theyre used to. After using the app multiple times with this pause, you brain will stop expecting the instant gratification. As a result, ideally, youll begin to use the app less.

One thing I noticed is that, depending on how often I used an app, the breathing pause would become even longer. This is because artificial intelligence automatically adjusts the wait time, depending on how addicted you are to an app. The more you use an app, the longer it forces you to wait.

While the app hasnt made a drastic change in my thinking or feeling about my app use in just one week, I do feel less emotionally dependent on Instagram likes. Maybe part of this is knowing that a computer program is withholding likes from me, and that ultimately, the number doesnt matter.

According to Mayberry, Dopamine Labs is one of the few if not the only company using our technology for good. Its Dopamine Labs goal to help us modify our behavior in positive ways. Space was originally blocked from the Apple app store because Apple didnt want to sell anything that made people use their phones less. Then, as Mayberry puts it, Apple decided they wanted to be on the right side of history. Now, it offers the app Space.

Kicking app addiction can be hard and it makes sense, considering how much money goes into paying companies like Dopamine Labs to keep us hooked. On my laptop, I found myself changing tabs to go to different websites rather than breathing one breath with the app because I still needed that instant gratification. Hopefully, continuing to use Space and taking more moments of mindfulness will help me snap out of that. Ive found one new app addiction, but I think its a good one.

Space is available in Apple iOS,Android, and on Chrome as an extension.

Related on Organic AuthorityDo You Have a Smartphone Addiction?5 Ways High-Tech Gadgets Ruin Your Body5 Signs Your Exercise Addiction Might Make You Obsess Over Fitness Trackers and Nutrition Apps

Lauren Krouse is an autodidact, travel addict, amateur Buddhist philosopher, and proud black lab mama. She believes in sounding her barbaric yawp over the roofs of the world Whitman-style and is frequently found writing in the woods perched on a log or reading on the coast with her belly in the sand.

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I Tried a Mindfulness App to Fight My App Addiction - Organic Authority

The neuroscience of paper emotions – Pulp & Paper Canada

Jul. 4, 2017 - This June, the results of a unique survey to determine the preference for the use of paper over digital communications were released after a yearlong process that involved the input of more than 7,000 consumers across 10 countries.

The survey, according to Two Sides, concludes that there is a clear preference for print on paper across all countries and regions analyzed. It found that 85 to 89 per cent of respondents agree, that when forests are responsibly managed, it is environmentally acceptable to use trees to produce products such as wood for construction and paper for printing. In the same vein, 88 to 91 per cent of respondents agreed that, when responsibly produced, used and recycled, print and paper can be a sustainable way to communicate.

These findings may also be partially explained by neuroscientific studies that have shown that our brains have a much more emotional and meaningful connection when we read on paper versus screens, wrote Two Sides Phil Riebel. Another neuroscience study was recently commissioned by Canada Post to illustrate the attractiveness of direct mail over online and email advertising.

A Bias For Action, produced by True Impact Marketing, used brain imaging and eye-tracking technologies to see into the brains of people interacting with physical (direct mail) and digital (email, display) advertising media. The researchers developed two integrated campaigns featuring mock brands, applying the same creative and messaging across both physical and digital media formats. The 270 participants were later given memory tests to assess their recall of branded material.

True Impact Marketing found that it takes 21 per cent less thought to process direct mail over digital messaging, and that the paper product creates a 70 per cent higher brand recall. Researchers found the motivation response created by direct mail is 20 per cent higher and even better if it appeals to senses beyond touch, such as smell and hearing. They also found direct mail gets the message across faster, explaining that our brains process paper media quicker than digital media.

Physical fills a much-needed, and very human, sensory deficit in the virtual world, where we spend most of our time these days...The most important renaissance in advertising has gone largely unnoticed, wrote Deepak Chopra, Canada Post president and CEO in a guest editorial column for The Globe and Mail. In their race to find the next big breakthrough, marketers didnt stop to realize that paper catalogues and marketing mail are emerging as an effective tool, even to engage digital natives. If there is one thing Steve Jobs taught us well, it is that customers dont always know what they really want. You have to figure it out for them.

This column was originally published in the Summer 2017 issue of Pulp & Paper Canada.

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The neuroscience of paper emotions - Pulp & Paper Canada