How a Few Drops of Blood Led to An Immunology Breakthrough – Drug Discovery & Development

Scientists from the Research Institute of the McGill University Health Centre (RI-MUHC) may have cracked the code to understanding the function of special cells called regulatory T Cells. Treg cells, as they are often known, control and regulate our immune system to prevent excessive reactions. The findings, published in Science Immunology, could have a major impact in our understanding and treatment of all autoimmune diseases and most chronic inflammatory diseases such as arthritis, Crohns disease as well as broader conditions such as asthma, allergies and cancer.

Researchers made this discovery by investigating a rare human mutation in a gene called FOXP3. Although the importance of the FOXP3 gene in the proper function of Treg cells has been well documented, its mechanisms were still not fully understood by scientists.

We discovered that this mutation in the FOXP3 gene affects the Treg cells ability to dampen the immune response, which results in the immune system overreacting and causing inflammation, explains the studys lead author, Dr. Ciriaco Piccirillo, immunologist and senior scientist in the Infectious Diseases and Immunity in the Global Health Program at the RI-MUHC, and a professor of Immunology at McGill University. This discovery gives us key insights on how Treg cells are born and how they can be regulated.

Thanks to an international collaboration and cutting-edge technology from the Immunophenotyping Platform at the RI-MUHC, the team was able to make their discovery using only a few drops of blood from a five-week-old newborn boy who died in 2009 from a rare and often fatal inherited genetic immune disorder called IPEX. In the past 40 years, fewer than 200 cases of IPEX have been identified worldwide. Over 60 different mutations of the FOXP3 gene are known to cause IPEX and believed to result in non-functional Treg Cells.

What was unique about this case of IPEX was that the patients Treg cells were fully functional apart from one crucial element: its ability to shut down the inflammatory response, says Dr. Piccirillo.

Understanding this specific mutation has allowed us to shed light on how many milder forms of chronic inflammatory diseases or autoimmune diseases could be linked to alterations in FOXP3 functions, adds the studys first author, Khalid Bin Dhuban, a postdoctoral fellow in Dr. Piccirillos laboratory.

From fundamental biology to clinical treatment

Dr. Piccirillo and his colleagues have already developed a molecule that could restore the Treg cells' ability to control the immune system for patients with the same rare mutation. The drug has been tested in animal models and the researchers are hopeful they can also develop similar drugs that will apply for other conditions where Treg cells are known to be slightly defective such as arthritis, type I diabetes, multiple sclerosis and lupus.

"Currently, we have to shut down the whole immune system with aggressive suppressive therapies in various autoimmune and inflammatory diseases," explains Dr. Piccirillo. Our goal is to increase the activity of these Treg cells in certain settings, such as autoimmune diseases, but we want to turn it down in other settings, such as cancer. With this discovery, we are taking a big step in the right direction.

Dr. CiriacoPiccirillo is also the director of theCentre of Excellence in Translational Immunology (CETI), a newly established research coalition based at the Research Institute of the MUHC that fosters linkages among biomedical investigators and clinicians for interdisciplinary immunology research focused on the understanding and treatment of immune-based diseases.

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How a Few Drops of Blood Led to An Immunology Breakthrough - Drug Discovery & Development

Trump vs Putin: anatomy of an underhanded handshake – Telegraph.co.uk

Today is an historic day, as world leaders from each oftheG20 nations have gathered in Hamburg to watchDonald Trump and Vladamir Putin shake hands (and also discuss geopolitics and climate change and other such secondary stuff).

Trump's unorthodox handshakingmethodhas been the subject of much scrutiny. His typical technique has been the 'clasp, yank, release':a powerplay that sees him draw his interlocutor close, whether they like it or not.

Given Putin's similarly elaborate taste in alpha male posturing (remember his shirtless horseback riding phase?), speculation has been rife: will Trump try his usual tactics again?

Let's dissect exactly how it went down when these two titans clashed.

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Trump vs Putin: anatomy of an underhanded handshake - Telegraph.co.uk

The ‘Rick And Morty: Anatomy Park’ Board Game Is Almost Here – Konbini US

Can't stand to wait another two weeks for the release of Rick and Morty season 3? In that case, create your own wacky adventure by getting the Rick and Morty: Anatomy Park board game.

That's right, of all the disgusting, crazy and bonkers adventures the mad scientist and his grandson have gone through, you can now relive the season 1 episode that sees the duo venture into a microscopic theme park built inside Ruben, the homeless Santa.

(Image: Konbini)

As you've probably guessed, the goal of the game is to successfully build a theme park inside the human body. Just like the characters in the series, you'll have to face many diseases and bodily reactions to win.

However, since it's a Rick and Morty-themed game, there's a catch! If someone pulls a "Bodily Reaction" card, the holder will actually have to act out its actions. Each player will get to choose between Rick, Morty, Annie, Poncho, Roger and park operator Dr. Xenon Bloomone, all of which featured in the episode.

The game itself will feature all you need to spend a gruesome, yet hilarious evening:

46 park tiles;Nine focus group tiles;14 bodily reactions cards;Three dice;Six oversized character cards;Six character standees;Six disease standees;Six Master Plan cards;30 control cubes;Lots of Victory Points tokens;Rulebook.

Lead designer Matty Hyra announced the game will also include exclusive attractions that did not feature in the original episode. As long as "Pirates of the Pancreas" and the friendly Hepatitis C are there, it'll be a hit for sure.

Rick and Morty: Anatomy Park comes out on July 12 and is expected to cost $30.

ReadMore ->Microsoft Put The Entire First Season Of 'Dragon Ball Z' Online For Free

I like watching films and going to music festivals. Get in touch at aurelien.huet@konbini.com

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The 'Rick And Morty: Anatomy Park' Board Game Is Almost Here - Konbini US

‘Heart, guts’ are anatomy to Clear Spring’s 11-12 win over Maugansville – Herald-Mail Media

MAUGANSVILLE An 8-0 deficit didnt stop Clear Spring against Maugansvilleon Fridayin the 11-12 District 1 losers bracket semifinal.

Six of those eight runs were credited to Spencer Wray on two home runs, including a grand slam. But Clear Spring answered with 12 straight runs to pull out the 12-9 victory and advance to todays losers bracket final at Conococheague.

Seven of those (12 runs) came with two outs. Thats remarkable, Clear Spring manager Brad Poffenberger said. These kids have heart and guts. That, as a coach, you cant teach. I cant give it to them, and I cant take it out of them.

Malakai Cunningham led Clear Spring with two home runs and four RBIs.

It took two innings for Maugansville to take the 8-0 lead. Wray homered in each inning, while John Blanco scored on an error in the first and Dylan Shoemaker had an RBI single in the second.

With one out in the bottom of the second Clear Spring cut the deficit in half as Hunter Oaks scored on a wild pitch and Cunningham and Keller Knode each hit home runs to make it 8-4.

Oaks and Caleb Younker tallied RBIs in the third before Cunningham blasted his second homer to left center that tied the game at 8-8. Nate Meyers broke the tie two batters later on an RBI double.

Honestly, when we got the big lead, I think some of them might have shut down thinking we had the game won, Maugansville manager Nick Shifler said. (Clear Spring) battled back and didnt quit. They ended up outplaying us in the end.

Clear Spring wasnt finished yet. Younker and Knode combined for three RBIs in the fourth to take a four-run lead.

With two outs in the top of the sixth, Shoemaker drove in Maugansvilles ninth run on a fielders choice, before Cunningham closed out the win for Clear Spring with a strikeout.

I know the kids are bummed out and theyre really down, but I told them they have nothing to put their heads down about, Shifler said. They worked their way through the losers bracket and they made a good run at it. We had a lot of positive moments.

Im very proud of my guys. Theyre a real special group of kids. Its an honor and a privilege to be a part of this team and to coach them. In the long run, us as coaches just hope that we somehow make a positive impact on their lives.

Poffenberger was already looking forward to todays game against Conococheague.

Here we come Conococheague, he said. Hopefully well redeem ourselves against Conococheague over the years Ive coached. Hopefully its going to be a good game for everybody. This teams fired up and ready to go.

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'Heart, guts' are anatomy to Clear Spring's 11-12 win over Maugansville - Herald-Mail Media

Comic-Con: ‘Black Panther’, ‘Logan’, ‘Cloak & Dagger’ Composers Set For Superhero Music Panel – Deadline

The composers behind some of the biggest superhero blockbuster films and fan-fave TV series are headed to Comic-Con for Costa Communications fifth annual Musical Anatomy of a Superhero panel. The event will take place on Thursday, July 20 at the Hilton Bayfronts Indigo Ballroom at 10am.

Composers will expound on their process and challenges in creating the musical voices behind the superheroes, as well as on collaborating with directors and producers. The panel event also will include unreleased clips of upcoming projects.

This years panelists include Oscar nominated and Emmy winning composer Mark Isham, who is composing the music for Freeforms upcoming Marvel series Cloak & Dagger.A reminder to die-hardOnce Upon a Timeattendees, Isham also writes the music for that show.

Two-time Oscar nominee Marco Beltrami (Logan, The Wolverine,Lucifer)will also be on hand. Swedish composer Ludwig Goransson will provide insight into Marvels upcoming February feature releaseBlack Pantherand MGM/Annapurnas reboot ofDeath Wish. Also on the panel:Emmy-nominated composer Brian Tyler, who wrote the music forAvengers: Age of Ultron, Power Rangers, The Mummy; David Russo, (Gotham,Nikita,The Tomorrow People);and Lorne Balfe (The Lego Batman Movie, the upcoming Warner Bros./Skydance picGeostorm).Costa Communications chief Ray Costa will be moderating the session.

Previous composers at Musical Anatomy includeChristophe Beck(Ant-Man, Frozen),Tyler Bates(Guardians of the Galaxy Vol.2),Blake Neely(Arrow, Super Girl, The Flash),John Powell(the Bourne Franchise, Hancock),Tom Junkie XL Holkenborg(Deadpool, Mad Max: Fury Road),John Ottman(X-Men: Apocalypse, Superman Returns),andJohn Debney(Iron Man 2).

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Comic-Con: 'Black Panther', 'Logan', 'Cloak & Dagger' Composers Set For Superhero Music Panel - Deadline

Anatomy Of A Love Triangle: Reporter And Church Choir Director Tries To Kill Man To Be With His Wife – Oxygen (blog)

Rob Whedbee woke up to the smell of cigarette smoke. Big problem: nobody in his house smoked. He opened his eyes to see a figure approaching him in his bed, silhouetted by the streetlight outside. The figure was carrying a knife according to Snapped on Oxygen.

He had one foot on the ground and he had one knee on the bed straddling me. You know, preparing to stab me or cut my throat, Rob said. He jumped out of the bed and began fighting the intruder. Robs wife Lisa appeared in the bedroom doorway with a baseball bat. Rob yelled to his wife for help but she just stood there. Then the intruder began yelling at Lisa. Hit him. Youve got to do it and youve got to do it now.

Lisa and Rob met in 1979, when they were both out driving. Rob asked Lisa, then 17, out on a date. She was smitten by the former high school football player turned college freshman. They dated for two years, and friends called them Barbie and Ken.

The seemingly dreamy couple wed in 1982. Rob began working for his familys insurance agency and so did Lisa until she had children. They bought a home and in 1986, they gave birth to their first child Justin. Their relationship was flourishing, even with the new baby. Sometimes Lisa and Rob would even slip off for a romantic weekend alone at their vacation condo in the Smoky Mountains.

The problems began after the birth of the couples daughter Brittany in 1990. The doctor informed the Whedbees that Brittany had been born with Down Syndrome and a heart defect. According to Rob, Lisa took the news very hard. Brittany survived multiple surgeries and, despite her medical problems, grew into a loving little girl. But, Lisa was having a hard time dealing with it. According to Rob, she never quite adjusted to the day-to-day stress of being a stay-at-home mom to a child with special needs.

Something like that sometimes as they say it can make you or break you and I think it broke her, he said.

Friends noticed that Lisa became more withdrawn. The birth of Brittany put a strain on her and Robs relationship. According to Rob, she became distant and in the spring of 1993, she suggested they get a divorce. Rob didnt like that idea.

The two went went to counseling at their church and tried to tough it out. That prompted Lisa to take a more active role at their Trinity Methodist. Lisa even signed up for the church choir, where she met a man named Michael Frazier. He was an organist who directed the church choir. He was also a reporter for the local newspaper. Oh, and he was a big time chain-smoker.

Paul Jones, a friend of Lisas, called Michael odd.

When he played he had that Phantom of the Opera kinda thing going on.

On Mothers Day in 93, Michael wrote a newsstory about the Whedbees, specifically Lisa, about raising Brittany.

I dont think my name was even mentioned in that story, said Rob. It was one of those things that you look at and you say huh thats kind of strange. You know where am I? Im left out and shes mother of the year.

Around this time, Lisa began coming home late on a regular basis. Rob began suspecting that Lisa and Michael were having an affair.

His suspicion was right, and it was a lot deeper than an average affair.

Rob recognized Michael's voice as he was attacking him.

So, I just stood up and picked him up over my head and slammed him into the corner by the nightstand and took off out of the room. And as I went past Lisa I took the baseball bat away from her. I squared off in the middle of the garage. I had the bat; he came out into the light and he had that knife in his hand, rubber gloves on, stocking mask, a black tee shirt.

Not just any tee. It was a 'Phantom of the Opera' shirt. As Rob left the house, Michael went back inside, shut that door and locked it. Enraged about the attempt on his life, Rob circled the house, beating on the gutters with the baseball bat. A neighbor heard the commotion and found Rob covered in blood, walking around in his underwear. The neighbor was stunned by the news that their choir director had just tried to kill Rob. They called 911.

While police were en route, Lisa came out of the house and walked up to Rob, pretending she didnt know what happened and that she didnt know who the attacker was.

Police arrived and interviewed Lisa. They noticed that she didnt seem that concerned about her husband. Placed in the back of a patrol car and read her rights, Lisa still denied being in on the attack, but she did confirm the identity of her husbands attacker. Frazier was also arrested. He confessed to both an affair with Lisa and to being the hit man in Rob's murder plot.

Lisa and Michael were both booked on attempted murder charges. Lisa was also charged with solicitation to commit murder.

Joe Anderson, friend of Rob, said he was very shocked by Lisas taste in the other man.

She could go out, being an attractive girl, and get basically anybody she wanted. Why would she cheat with someone like this?

The unlikely love triangle caught the attention of national news outlets like People, Dateline, CNN and Hard Copy.

Now it was Rob who wanted the divorce. He filed and Lisa, despite her earlier desire to end the marriage, contested. Because of LIsas attempted murder charges, Rob was able to obtain temporary custody of the couples two children. He also obtained a restraining order against Lisa, who was out on $50,000 bond. Awaiting trial, Lisa continued her affair with Michael Frazier, who was also out on $50,000 bond. The former choir director frequently visited Lisas condo, the once romantic getaway for her and Rob, even though Lisa was under specific direction from the judge to not see Michael.

Lisa began claiming the Rob was physically abusive to her. She also said he threatened her life when she tried to divorce him. Rob denied the allegations, arguing that they were all about diverting attention from her pending criminal case.

Michaels trial came first. In their opening statements, prosecutors argued that the attempt on Robs life was the result of meticulous planning on the part of Lisa and Michael. The defense admitted that with the knife in the Whedbees bedroom in their open. But, they argued he had a very legitimate reason to attack Rob: Lisa told Michael that Rob abused and sexually assaulted her. And, soon, the very non-threatening Michael took the stand.

It was important not only what Michael said, but to allow them [the jury] to see this very diminutive, almost kind of dorky and, and, in ways, effeminate person, said Michaels attorney, Greg Isaacs.

I was going to do whatever I had to do to protect Lisa, Michael said to the court.

Prosecutors claimed that Lisas looks made it easy for her to manipulate the choir director.

The jury found Michael Frazier guilty but not of attempted murder. They convicted Frazier of the lesser charge of attempted manslaughter, punishable by a maximum of only four years in prison. The judge sentenced him to all four.

Lisa didnt have a trial. She opted for a plea deal instead. She entered an Alford Plea, in which a defendant never admits guilt, but pleads guilt because they believe it to be in their best interest to do so. Lisa served less than a year in jail, followed by three years probation.

Neither one of them got what they deserved. Thats a fact, said Rob.

Lisa has since remarried, and built a new life in another state.

Lisas attorney, David Eldridge, said, Among the saddest of the chapters is the destruction of the relationship that she had, very positive relationship she had with the children and thats a huge price to pay, and shes paid it Im afraid.

Rob raised Justin and Brittany as a single dad.

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Anatomy Of A Love Triangle: Reporter And Church Choir Director Tries To Kill Man To Be With His Wife - Oxygen (blog)

‘Grey’s Anatomy’ season 14 spoilers: Have we seen the last of Eliza … – Hidden Remote

Photo Credit: Grey's Anatomy/ABC Image Acquired from Disney ABC Media MARIKA DOMINCZYK, JESSICA CAPSHAW

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Photo Credit: Greys Anatomy/ABC Image Acquired from Disney ABC Media

From the minute Dr. Eliza Minnick waltzed into the hallways of Grey Sloan Memorial in the seventh episode ofGreys Anatomythirteenth season as the doctor brought in to take Richards place as the hospitals Residency Director, she was fighting an uphill battle. Unfortunately for Dr. Minnick, her actions only made things worse and she quickly became one of the most hated characters in the history of the show.

When the Season 13 finale rolled around, Dr. Minnicks robotic approach to medicine and inability to see beyond a patients charts finally caught up with her. After the dust settled from the explosion thatturned the hospital upside down, Bailey finally decided to take a stand for Richard by firing Dr. Minnick from her position due to her actions during the hospital crisis. But have we truly seen the last of Dr. Minnick or will she somehow manage to find a way to stay on staff at the hospital come Season 14?

While ABC has not yet commented on her portrayer Marika Dominczyks status on the show,Dominczyk is currently not credited beyond the Season 13 finale. Add that to the fact that Dr. Minnick was fired in the finale and it seems highly likely that Dr. Minnick has left the building for good!

Greys Anatomyreturns for its fourteenth seasonThursdays this fall on ABC. Be sure to tune in!

OkayGreysfans, time to join the conversation! Do you hope that weve seen the last of Dr. Eliza Minnick after the way in which her character was introduced in Season 13 or would you like to see Dr. Minnick get a shot a redemption? Keep the conversation going in the comments section below!

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'Grey's Anatomy' season 14 spoilers: Have we seen the last of Eliza ... - Hidden Remote

Self-Driving Cars Will Soon Make Moral Decisions As Well As Humans – IFLScience

In his book The Descent of Man, and Selection in Relation to Sex, Darwin proudly argued that our sense of morality was a uniquely human trait. Even though that claim has been disputed in recent years, its fair to say humans still top the charts when it comes to moral senses.

But it looks like we might soon have some competition, namely in the form of driverless cars.

A new study in the journal Frontiers in Behavioral Neuroscience has looked at human behavior and moral assessments to see how they could be applied to computers.

Just like a human in a car, a driverless car could be faced with split-second moral decisions. Picture this: A child runs into the road. The car has to work out whether it hits them, veers off to hit a wall and potentially kill other passersby, or hit the wall and potentially kill the driver.

It was previously assumed that this kind of human morality could never be described in the language of a computer as it was context dependent.

But we found quite the opposite, Leon Stfeld, first author of the study, said in a statement.

Human behavior in dilemma situations can be modeled by a rather simple value-of-life-based model that is attributed by the participant to every human, animal, or inanimate object."

They worked this out by asking participants to drive a car in a typical suburban neighborhood on a foggy day in an immersive virtual-reality simulation. During the simulation, they were faced with unavoidable crashes with inanimate objects, animals, people, etc. Their task was to decide what object the car crashes into.

The results were then plugged into statistical models leading to rules to work out how and why a human reached a moral decision. Remarkably, patterns emerged.

Now we have worked out the laws and mechanics in the way a computer would understand, it means we could now simply teach machines to share our morality. This will have some huge implications in regards to self-driving cars.

We need to ask whether autonomous systems should adopt moral judgments, if yes, should they imitate moral behavior by imitating human decisions, should they behave along ethical theories and if so, which ones, and critically, if things go wrong who or what is at fault? senior author Professor Gordon Pipa said.

"Now that we know how to implement human ethical decisions into machines we, as a society, are still left with a double dilemma," Professor Peter Knig, another senior author, added. "Firstly, we have to decide whether moral values should be included in guidelines for machine behavior and secondly, if they are, should machines act just like humans."

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Malaysia, Indonesia Muslim groups call for Starbucks boycott over LGBT stance – Washington Examiner

Muslim groups in Malaysia and Indonesia are calling for a Starbucks boycott due to the company's support of LGBT issues.

The Muslim Malaysian group Perkasa called on its members to boycott Starbucks coffee shops this week, the Associated Press reported.

"Our objection is because they are promoting something that is against human instinct, against human behavior and against religion," Amini Amir Abdullah, Perkasa's Islamic affairs bureau chief, told Reuters. "That's why we are against it."

Perkasa called on the Malaysian government to revoke trading licenses for Starbucks, as well as other companies like Microsoft and Apple.

The call came days after an Indonesian Islamic group, Muhammadiyah, also denounced the coffee chain in the nation with the world's largest Muslim population.

According to the Associated Press, shares in the company that operates Starbucks in Indonesia fell and a boycott Starbucks hashtag was popular for a short time.

Amini said the call for boycott stemmed from a report that Starbucks chairman Howard Schultz supports gay marriage. In 2013 Schultz, who was Starbucks CEO at the time, responded to a question from a shareholder who suggested that Starbucks had lost customers due to its support of LGBT rights by saying, "Not every decision is an economic decision. The lens in which we are making that decision is through the lens of our people."

"Though we are founded in the United States, we are a global company with over 300,000 partners and 26,000 stores in 75 markets around the world," a Starbucks spokesperson told the Washington Examiner. "In all countries where we do business, we are proud to be a part of the fabric of the local community, and we strive to be respectful of local customs and traditions while staying true to Starbucks long-standing values and purpose."

Sodomy is illegal and punishable by up to 20 years in prison in Malaysia and, while homosexuality is not illegal in Indonesia, Indonesia's Constitutional Court is looking to make homosexual sex and sex out of wedlock a criminal activity, the Associated Press reported.

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Malaysia, Indonesia Muslim groups call for Starbucks boycott over LGBT stance - Washington Examiner

NewLink Genetics to Host Its Second Quarter 2017 Financial … – GlobeNewswire (press release)

July 07, 2017 07:00 ET | Source: NewLink Genetics Corporation

AMES, Iowa, July 07, 2017 (GLOBE NEWSWIRE) -- NewLink Genetics Corporation(NASDAQ:NLNK), today announced that it will release its second quarter 2017 financial results onFriday, July 28, 2017. The company has scheduled a conference call for8:30 AM ETthe same day to discuss the results and to give an update on its clinical and development activities.

NewLink Genetics'senior management team will host the conference call, which will be open to all listeners. There will also be a question and answer session following the prepared remarks.

Access to the live conference call is available by dialing (855) 469-0612 (U.S.) or (484) 756-4268 (international) five minutes prior to the start of the call. The conference call will be webcast live and a link can be accessed through theNewLink Geneticswebsite athttp://edge.media-server.com/m/p/mqa6eh65. A replay of the call will be available for two weeks from the date of the call and can be accessed by dialing (855) 859-2056 (U.S.) or (404) 537-3406 (international) and using the passcode 51432155.

AboutNewLink Genetics Corporation

NewLink Geneticsis a late-stage biopharmaceutical company focusing on discovering, developing and commercializing novel immuno-oncology product candidates to improve the lives of patients with cancer.NewLink Genetics'IDO pathway inhibitors are designed to harness multiple components of the immune system to combat cancer.Indoximod is being evaluated in combination with treatment regimens including anti-PD-1 agents, cancer vaccines, and chemotherapy across multiple indications such as melanoma, prostate cancer, acute myeloid leukemia, and pancreatic cancer. For more information, please visithttp://www.newlinkgenetics.com.

Cautionary Note Regarding Forward-Looking Statements

This press release contains forward-looking statements ofNewLink Geneticsthat involve substantial risks and uncertainties. All statements, other than statements of historical facts, contained in this press release are forward-looking statements, within the meaning of The Private Securities Litigation Reform Act of 1995. The words "anticipate," "believe," "estimate," "expect," "intend," "may," "plan," "target," "potential," "will," "could," "should," "seek" or the negative of these terms or other similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. These forward-looking statements include any statements other than statements of historical fact. Actual results or events could differ materially from the plans, intentions and expectations disclosed in the forward-looking statements thatNewLink Geneticsmakes due to a number of important factors, including those risks discussed in "Risk Factors" and elsewhere inNewLink Genetics'Annual Report on Form 10-K for the year endedDecember 31, 2016and other reports filed with theU.S. Securities and Exchange Commission (SEC). The forward-looking statements in this press release representNewLink' Genetics'views as of the date of this press release.NewLink Geneticsanticipates that subsequent events and developments will cause its views to change. However, while it may elect to update these forward-looking statements at some point in the future, it specifically disclaims any obligation to do so. You should, therefore, not rely on these forward-looking statements as representingNewLink Genetics'views as of any date subsequent to the date of this press release.

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NewLink Genetics to Host Its Second Quarter 2017 Financial ... - GlobeNewswire (press release)