Biochemistry

Scientists uncover a hidden calcium cholesterol connection – Phys.org – Phys.Org

Marek Michalak, a professor in the University of Alberta's Department of Biochemistry and graduate student Wen-An Wang were part of the team that discovered a direct link between calcium and cholesterol. Credit: Melissa Fabrizio

It's well known that calcium is essential for strong bones and teeth, but new research shows it also plays a key role in moderating another important aspect of healthcholesterol.

Scientists at the University of Alberta and McGill University have discovered a direct link between calcium and cholesterol, a discovery that could pave the way for new ways of treating high blood cholesterol.

The researchers began the work after having their curiosity piqued while studying the role of a calcium-binding protein. They noticed an extreme rise of blood cholesterol concentration in mice when the protein was not present. To follow up on this observation, Marek Michalak with graduate student Wen-An Wang (University of Alberta) and Luis Agellon (McGill University) teamed up with geneticist Joohong Ahnn (Hanyang University, Korea) and discovered that the physiological link between calcium and cholesterol is also preserved in worms.

"There is a mechanism inside the cell that senses when there is not enough cholesterol present and turns on the machinery to make more," said Michalak, a distinguished university professor in the University of Alberta's Department of Biochemistry. "What we found is that a lack of calcium can hide cholesterol from this machinery. If you lose calcium, your synthetic machinery thinks there's no cholesterol and it starts making more even if there is already enough."

High blood cholesterol is a known risk factor for developing heart disease. "Factors that affect blood cholesterol concentration have been studied for a long time," said Agellon, a professor at McGill's School of Human Nutrition. "The general belief was that cholesterol controlled its own synthesis inside of cells, and then we discovered in our labs that calcium can control that function too. Finding this link potentially opens a door to developing new ways of controlling cholesterol metabolism."

The researchers consider their finding a significant step toward developing different approaches to patient care in the future, but there is more work to be done. They are now looking to discover the common factor that allows calcium and cholesterol to communicate with each other in the cell and have received a four-year grant worth $456,000 from the Canadian Institutes of Health Research to continue their work.

Explore further: What you need to know about cholesterol

More information: Wen-An Wang et al, Loss of Calreticulin Uncovers a Critical Role for Calcium in Regulating Cellular Lipid Homeostasis, Scientific Reports (2017). DOI: 10.1038/s41598-017-05734-x

See more here:
Scientists uncover a hidden calcium cholesterol connection - Phys.org - Phys.Org

Biochemistry

Molecules That Could Form ‘Cell-Like’ Membranes Spotted on Saturn’s Largest Moon – Gizmodo

Titan, partially obscured by Saturns rings. Image: NASA/JPL-Caltech/Space Science Institute

Saturns moon Titan is a world of contrast; both eerily familiar and strikingly alien. Its calm seas and enormous sand dunes might remind you of Earth, until you learn that whats flowing across Titans surface is not water, but liquid hydrocarbons. Titans nitrogen-rich atmosphere seems to have some of the ingredients for biology, but any life forms evolved to thrive at temperatures of -290 degrees Fahrenheit would be practically unrecognizable.

A new scientific paper supports the idea that life might exist on Titan, but that it would be nothing like life as we know it. After studying spectroscopic data collected by the Atacama Large Millimeter/sub millimeter Array (ALMA) in northern Chile, researchers are now reporting that Titans atmosphere is rife with vinyl cyanide, a molecule that could, in theory, form cell-like membranes under the moons unique environmental conditions.

In fact, based on the levels of vinyl cyanide present in Titans atmosphere, its seas couldin theory, were not saying there are aliensbe bubbling with tiny cell membranes, with concentrations similar to those of bacteria in Earths oceans.

The membranes that enclose the cells of all living things here on Earth are made of phospholipids, molecules with long, non-polar (water-repelling) tails and polar (water-loving) heads. If you remember high school biology, youll know that phospholipids form a bi-layer, with the water-loving parts on the outside, and the water-repelling bits on the inside. This structure allows membranes to bubble off tiny pockets of water from their surroundings, creating cells that house genetic material and support biochemical reactions.

Thats all well and good for organisms evolved to thrive in the temperate, liquid water seas here on Earth, but the membranes our biology uses simply wouldnt work in the cryogenic methane seas of Titan. (Theyd be far too rigid, and water-loving/water-repelling bits would have to be reversed.) So, what could cells on Titan look like? Two years back, researchers at Cornell University used chemical models to attempt to answer that very question. Through those models, they produced a functional cell membrane that remained stable and flexible at incredibly low temperatures, using none other than C2H3CN, or vinyl cyanide.

They called their hypothetical alien cell an azotosome.

What makes vinyl cyanide potentially useful molecule for this is that its amphiphilicit has a polar and a non polar end, just like our membranes phospholipids, Maureen Palmer, a recent graduate of St. Olaf College and lead author on the new study,explained. It would be sort of the same but sort of the opposite of how cell membrane lipids work on Earth, with the polar bits on the inside, and the non-polar bits on the outside.

It was a fascinating hypothesis, but there was one problemnobody had ever confirmed that vinyl cyanide is actually present on Titan. (NASAs Cassini spacecraft found tentative evidence for the molecule several years back.) Palmerand her colleagues decided to fill in this gap, by examining calibration data ALMA collects at Titan before turning its telescopes to stare at other targets. Sure enough, they found compelling evidence that large amounts of vinyl cyanide are present in Titans atmospheremainly, at altitudes greater than 200 kilometers. The research was published today in Scientific Reports.

When I sent the paper to Jonathan Lunine, Cornell astronomer and co-author on the 2015 study positing the existence of azotosomes, he said it was quite gratifying to see that acrylonitrile, or vinyl cyanide, does indeed seem to be present in Titans atmosphere.

Of course, life as we know it would be more likely to emerge in the vast seas on Titans surface than high up in the sky. But as Palmer and her colleagues point out, rainfall is constantly transporting organic compounds to Titans surfaceand those could include vinyl cyanide. It should be reaching the surface, she said. Titan has lots of rain.

In fact, in Ligeia Mare, a methane sea larger than Michigans Lake Superior located near Titans north pole, Palmer and her colleagues estimate there could be as many as 30 million azotosomes per cubic centimeter of sea water. For comparison, costal ocean waters on Earth have about a million bacteria per cubic centimeter, according to one papers estimate.

This is a crucial point and lab experiments ought to be done, Lunine added. Palmer agreed.

Im hoping someone will do a study of trying to form the membranes in the lab, seeing if theyre actually able to form, she said. Her co-authors are currently trying to better constrain the abundance and distribution of vinyl cyanide in Titans atmospherethis first paper was just a rough look. Theyre also searching for evidence of other biologically-relevant molecules on Titan. Also this week, another team of scientists reported the detection of carbon chain anionspotential building blocks of complex biomoleculesin Titans upper atmosphere, using data from Cassini.

Ultimately, resolving the question of whether or not Titan is home to some seriously weird life forms will require a future mission that can land on its surfacemaybe a cryogenic methane-proof submarine. Palmer is definitely rooting for a lander.

I love Titan, Palmer said. Its super interesting as an astrobiology target, because all forms of life we know of on Earth have water as the solvent, but it has liquid methane. It would be a totally different form of biochemistry, if there was life on Titan. I find that possibility fascinating.

Read this article:
Molecules That Could Form 'Cell-Like' Membranes Spotted on Saturn's Largest Moon - Gizmodo

Immunology

Eli Lilly Signs Development Deal for Novel Immunology Drug – Drug Discovery & Development

Eli Lilly is bolstering its autoimmune offerings with a new co-development and commercialization agreement.

The deal will focus on a promising drug called NKTR-358, developed by Nektar Therapeutics. Its being designed to target the interleukin (IL-2) receptor complex in the body in an effort to stimulate the proliferation of regulatory T-cells. Activating these cells could bring the immune system back into balance.

As part of this agreement, Nektar will receive an initial payment of $150 million from Eli Lilly with the potential to receive an estimated $250 million if the drug achieves certain development and regulatory milestones, according to the announcement.

Investigators achieved the first human dose of NKTR-358 as part of a Phase I clinical trial in March 2017 with the goal of measuring observed changes and functional activity of regulatory T cells in approximately 50 healthy patients.

Both companies will co-develop NKTR-358 with Nektar being responsible for completing Phase 1 clinical development, but then the costs will shift for Phase 2 in which Lilly will handle 75 percent and Nektar the remaining 25 percent.

Furthermore, Nektar will be able to receive double-digit royalties that increase based on its Phase III investment and product sales with Lilly handling all costs of global commercialization.

"We are very pleased to enter into this collaboration with Lilly as they have strong expertise in immunology and a successful track record in bringing novel therapies to market," said Nektars President and CEO Howard W. Robin, in a statement. Importantly, this agreement enables the broad development of NKTR-358 in multiple autoimmune conditions in order to achieve its full potential as a first-in-class resolution therapeutic."

Proving this drugs mechanism of action is viable could ultimately yield a multi-purpose therapy that could work for autoimmune conditions like lupus and psoriasis.

Excerpt from:
Eli Lilly Signs Development Deal for Novel Immunology Drug - Drug Discovery & Development

Cell Biology

Biology faculty take part in national institute on scientific teaching – News at OU

With the goal of improving student learning, a select group of faculty members in Oakland Universitys Department of Biological Sciences attended a national conference dedicated to enhancing teaching methods in the STEM fields. Rasul Chaudhry, Shailesh Lal, Luis Villa-Diaz and Randal Westrick took part in this years Summer Institute on Scientific Teaching, which was held June 4-10 at the University of Minnesota.

The event, which was by invitation only, focused on helping university instructors in the STEM fields create an inclusive environment in which students of all backgrounds and learning styles can succeed.

Chaudhry, who has taught at OU for more than 30 years, said the institute allowed STEM professors to share ideas on how to improve student engagement in science, technology, engineering and mathematics, subjects with a reputation for being academically challenging.

We are always looking for ways to spark students interest. Some students struggle early on (in STEM subjects) and are turned off, Chaudhry said. They may develop a mindset that its too difficult or its just not for me. Our challenge as educators is to reach out to all students and help them see that STEM can be fun and interesting.

During the conference, participants engaged in interactive sessions, worked in small groups with a trained facilitator, and presented instructional materials for feedback and review. OUs team presented a lesson on epigenetics, which is the study of biological mechanisms that control gene expression.

Its a topic that must be taught with sensitivity, Villa-Diaz said, noting that epigenetics play a role in disease predisposition being passed from generation to generation. There could be students in the class who have family history of certain diseases, such as cancer.

The four professors were designated Scientific Teaching Fellows for their dedication to undergraduate education.

Participants discussed ways to maximize student engagement, such as implementing multilingual instruction for non-native speakers and closed captioning for students with hearing impairments. The concept of a flipped classroom in which students watch or listen to a lecture before class, and then engage in discussion and learning exercises during class, was also cited as a way to promote active learning.

Lal noted that an inclusive approach is particularly vital for professors who are teaching students of many different skill levels.

At most universities, professors are teaching a wide spectrum of students, Lal explained. So, were trying to keep the more advanced students interested, while also making sure that no one is left behind.

A students cultural background can also be a pathway to engagement, according to Chaudhry.

Most of the contributions to cell biology came from Caucasians, he said. But there are many other scientific contributions that were made by minorities.

At the conclusion of the institute, participants received a certificate designating them a Scientific Teaching Fellow in recognition of their demonstrated commitment to undergraduate education.

OUs team will be organizing workshops to share what theyve learned with colleagues across campus.

The plan is to spread the message so that we can all use these strategies, Westrick said. We want to attract and retain as many students as possible in STEM. These fields are not only financially rewarding, but also rewarding in terms of their potential to improve peoples lives and make the world a better place.

Financial support for the participants was provided by the Office of the Provost. The institute was jointly sponsored by the Howard Hughes Medical Institute, the Helmsley Charitable Trust and the Yale Center for Teaching and Learning.

See the original post here:
Biology faculty take part in national institute on scientific teaching - News at OU

Cell Biology

UCI researchers use stem cells as cancer-seeking missiles – 89.3 KPCC

A close-up of cell mutations that cause cancer. Steve Gschmeissner/Science Source

Chemotherapy is brutal a medicinal atomic bomb that destroys large swaths of cells, both cancerous and normal. And as a result, patients are often left physically devastated.

In a new study published in Science Translational Medicine, scientists at UC Irvine say they've come up with a way to use stem cells to help ameliorate those side effects. Think of it as a surgical strike with cancer-seeking missiles.

Professor Weian Zhao and his colleagues from UC Irvine modified stem cells so that they'd be attracted to enzymes released by breast cancer tumors. So, when injected into the body, the stem cells seek out the cells and bond with them.

The enzymes the scientists identified cause tissue to clump up into bundles of collagen and protein to create stiff tumors. The tumors become lumps that a patient can sometimes feel, and they act as a protective home for the cancerous cells.

The stem cells release an enzyme of their own, in turn, activating a type of chemotherapy that's been injected into the patient, which is inert until in comes in contact with the enzyme. The idea being that the chemotherapy only causes toxicity to a localized area, instead of destroying everything in its path.

"We can use a stem cells to specifically localize and produce the drugs only at the tumor site, so that we can spare the healthy tissue," said Zhao. "So, we can make the treatment more effective and less toxic to the patient."

"I think this is pretty unique in a way that it can target specific metastatic tissues with reduced toxicity overall," said Min Yu, assistant professor at the department of Stem Cell Biology and Regenerative Medicine at USC. "So, in that sense, I think it's very novel and very unique approach."

Yu, who was not involved in the research, complimented the UCI team's methods and results, especially how effective the treatment was on the particular cancer cell that they focused on. However, she said, from patient to patient and cancer to cancer, there are a myriad of different cells responsible, making treatment notoriously difficult to generalize. The therapy isn't a sure thing.

Zhao acknowledged that his team has a while to go before it can prove that the treatment is effective in people. So far, it's only been tested in mice. As a result, FDA approval and human trials could be years away.

View original post here:
UCI researchers use stem cells as cancer-seeking missiles - 89.3 KPCC

Neuroscience

Conde Nast uses neuroscience to prove its sponsor posts work – Digiday

Cond Nast is on a mission to prove itssponsored postsare resonating, using the backingof neuroscience.

In an attempt to demonstratethe efficacy of its branded videos on YouTube and Facebook, the media conglomerate teamed with market research firm Neuro-Insight to measurethe impact of its posts on memory encoding and emotional intensity. Using a method called steady state topography that monitors brainwave activity, Cond Nast tracked how 200 consumers interacted with its sponsored fashion, finance, beauty and auto posts.

The findings showed high levels of resonance forCond Nast posts across both platforms specifically, its videos were 60 percent more effective at memory encoding than traditional YouTube pre-roll advertising and 17 percent more engaging than general Facebook content, including user-generated posts from friends.

Josh Stinchcomb, chief experiences officer at Cond Nast, said ultimatelythe study served to affirm and legitimize the companysexisting digital efforts, butwill also help inform ways for the company to evolve across its brands.

Increasingly our social feeds and our YouTube channels are becoming major distribution points for all content we create, editorial and otherwise, he said. So much of advertising impact is subconscious. We really wanted to delve into how people were responding to advertising within the brain and get a more nuanced and holistic read.

Part of Cond Nasts higher resonance rates can be attributed to targeted advertising techniques that have made it easier to tailor content to a particular type of consumer or reader. For example, its now easier than ever to tailor fashion-centric Cond Nast videos to consumers using YouTube to seek outstyle tutorials. According to a recent study by social advertising consultancyStrike Social, fashion has the second highest ad viewership rate on YouTube across industries after education content at 13.4 percent higher viewership than the industry average, at 31.9 percent versus 27.7 percent.

Fashion has done very well at producing video content, said Jason Nesbitt, vp of media and agency operations at Strike Social. They have engaging creative and often have content that includes a popular celebrity, model of a good looking person. That always does well as far as viewership.

Enter today to join past winners like Ogilvy, Under Armour and Casper

Stephanie Fried, evp of research, analytics and business development at Cond Nast, said the studyprovides an important look at thesubconscious proclivities of its readers that helpsemphasize the impact of the companysads.

Opinions are subjective and relative to peoples individual perceptions while neuroscience is more objective and consistent across subjects,Fried said. There are some things people dont want to say but neuroscience still picks those things up. Its like a lie detector on the brain.

Nesbitt added that the benefit ofsponsored content in the digital age isbrands and publishers like Cond Nast can receiveinstantaneous analysisthat allows themto test campaigns.

Its not like traditional media where you choose a TVor radio station that might index higher due to a particular demographic, where you might not get the results till later and its harder to measure, he said. The luxury is having this data in real time and having these insights from the sheer mass data that you get.

Read the rest here:
Conde Nast uses neuroscience to prove its sponsor posts work - Digiday

Neuroscience

What the WARC 100 can learn from neuroscience – Warc

LONDON: The worlds most effective campaigns highlighted in the WARC 100 are doing many things right, but there is plenty of room for improvement, according to an industry figure.

Writing in the current issue of Admap, Heather Andrew, CEO of Neuro-Insight, outlines the extent to which previously identified key creative factors associated with long-term memory encoding are evident among campaigns in the 2017 WARC 100 where television advertising played a key role.

We found that, while almost all the winning campaigns consistently exploit some of these [six] key creative drivers, there are others that represent potential missed opportunities; and one factor to which even the strongest campaigns can be vulnerable, she reports.

The three factors that brands in the WARC 100 consistently exploited revolved around aspects of storytelling, including showcasing rather than overtly selling, making the brand intrinsic to the storyline, and having strong levels of interaction between characters all of which help drive memory encoding.

But Andrew identifies two areas that brands could better exploit: music and rhythm.

The highest levels of brain response are elicited by music that is perceived to drive the action, she notes, but many WARC 100 campaigns used a recessive soundtrack one that is present but which doesnt produce a higher response or which may even be a distraction that can have a negative effect on overall brand impact.

Effective use of breaks and pauses to direct the brain to key parts of the narrative elicit 20% higher memory response at key branding moments, but Andrew finds that many WARC 100 ads had an even rhythm with little contrast not necessarily a problem but potentially a missed opportunity.

More seriously, she warns that many run the risk of being damaged by conceptual closure when the brain pauses for a moment to process an aha! moment and for a second or so is unreceptive to new information.

Examples included taglines that sum up a story just prior to end branding, or executional details that act as a cue that the story is over before it actually is over.

The road to the WARC 100 is almost certainly littered with ads where great creative has failed to make a real-world impact as a result of conceptual closure, resulting in an ad that people love without ever being able to remember what brand was being advertised, Andrew says.

Data sourced from Admap

More:
What the WARC 100 can learn from neuroscience - Warc

Embryology

Embryology, LEGOS AND geocaching among activities at Youth Building – Uniontown Herald Standard

Visitors to the Youth Building during this years Fayette County Fair at the Fayette County Fairgrounds in Dunbar Township will have opportunities to see an embryology project, build Lego structures that reflect local landmarks and participate in geocaching as well as learn about 4-H.

Jennifer Deichert, Penn State Extension assistant, explained this years programs are being set up to run in blocks of time to allow fairgoers more flexibility to stop by anytime during these segments to learn about the subjects being presented.

The embryology project, which will be available in an area of the building throughout the fair, teaches life development. The project, which has been undertaken in several local schools through the years, uses chicken eggs that hatch into young chicks.

A program called Explore Embryology with 4-H will be available from 3 to 6 p.m. Friday, July 28 where presenters will be able to explain the process and answers questions to those who visit.

Well let them look at the little chicks and talk about opportunities in 4-H, said Deichert.

Explore Geocaching with 4-H will be presented with Williams Energy from noon to 4 p.m. July 31 to Aug. 4. Geocaching is a hobby in which a participant uses a GPS to search for hidden items called geocaches. Deichert said participants will learn how to geocache to find sites and exhibits throughout the fair.

Steel City LEGO User Group returns with building activities from 10 a.m. to 7 p.m. Sunday, July 30.

Im real excited. (Steel City LUG founder) Josh Hall will be here on Sunday with challenges that relate to something in the Laurel Highlands, Deichert said.

Without revealing specific commands, those challenges include:

Jumonville cross Participants will be asked to make a replica of the Great Cross of Christ that is a local landmark at this Christian camp in North Union Township.

Fallingwater Participants will be challenged to build a cantilever porch based on the concept used at Frank Lloyd Wrights internationally known Fallingwater in Mill Run.

Cave Those participating will be asked to build a cave similar to Laurel Caverns in Farmington, home to Pennsylvanias largest cave.

National Road markers Participants will try building a replica of the markers that denoted miles along the National Road, Americas first federal highway, that runs through Somerset, Fayette and Washington counties in Pennsylvania.

The 4-H Robotics Club will help with the LEGOS program and have their own demonstration from 1 to 2:30 p.m. Sunday, July 30. The club will also host LEGO challenges from 4 to 6 p.m. Tuesday, Aug. 1 and Thursday, Aug. 3.

Carnegie Science Center returns with a liquid nitrogen Make It and Take It activity from 2 to 5 p.m. on Friday, Aug. 4.

Other programs being held in the Youth Building during the fair include:

Explore STEM with 4-H from 3-6 p.m. Monday, July 31, and 2-5 p.m. Wednesday, Aug. 2.

Explore Agriculture and Plant Science with 4-H, 2-5 p.m., Tuesday, Aug. 1; Cloverbud Day: Activities for youths ages 5-8, 2-5 p.m., Friday, Aug. 4 and Explore Health with 4-H, 3-6 p.m., Saturday, Aug. 5.

Agriculture-related videos will run in the Youth Building during the fair.

In addition, GoPro cameras will be available to 4-H members to use for filming a video about the fair. Deichert noted one of this years new clubs is a 4-H Video Production Club.

A Fayette County tourism grant is providing funds for a television with a DVD player to show the agricultural videos as well as 10 GPS units for geocaching, LEGOS for the building challenges and GoPro cameras.

The Youth Building is also the site of the opening ceremony for the 63rd annual Fayette County Fair during which Bill Jackson, fair board president, welcomes the public and introduces fair board members, visiting officials and this years candidates for fair queen. The ceremony takes place at 6:30 p.m. on Thursday, July 28.

4-H clubs will have to set up displays about their clubs, 2-5 p.m., Thursday, and 10 a.m. to 5 p.m., Friday, that will be judged later in competition.

The Youth Building will also hold the popular Pennsylvania Preferred Chocolate Cake and Cookie competition Sunday. Entries are accepted from 9 a.m. to noon with judging at 1 p.m.

On Sunday, the 4-H Robotics Club will have a demonstration, 1-2:30 p.m., while the annual 4-H Fashion Show is scheduled for 3 p.m. and the 4-H Communication Contest is slated for 5 p.m.

4-H entries for a variety of projects are being accepted 8 a.m. to 5 p.m., Monday, July 31, with judging from 9 a.m. to 1 p.m. on Tuesday, Aug. 1.

The LH Literacy Van is slated to visit the Youth Building from 10 a.m. to 7 p.m., Friday, Aug. 4.

Follow this link:
Embryology, LEGOS AND geocaching among activities at Youth Building - Uniontown Herald Standard

Embryology

Senior IVF Specialist Dr. Sangeeta Jain Participates in ESHRE 2017 in Geneva, Switzerland – PR Newswire India (press release)

NEW DELHI, July 31, 2017 /PRNewswire/ --

Dr. Sangeeta Jain MBBS, MD (Obst & Gynae), Founder, JoyIVF Clinic, attended European Society of Human Reproduction and Embryology (ESHRE) 2017 that took place in Geneva, Switzerland earlier this month.This was the 33rdannual meeting of ESHRE which is aimed at promoting interest in, and understanding of, reproductive biology and medicine. It does this through facilitating research and subsequent dissemination of research findings in human reproduction and embryology to the different stakeholders.

A technical exhibition of pharmaceutical, surgical and laboratory products was organised in the sidelines of the congress. Several Pre-congress Courses were organised by ESHRE's Special Interest Groups on a variety of subjects including male infertility, enhancing endometrial receptivity, embryo transfer process and techniques, etc.

Several industry-sponsored sessions were also part of the programme. Some of the interesting topics included personalizing ovarian stimulation, natural diversity in ART outcome, insulin sensitizers and PCOS, amongst others.

JoyIVF believes that learnings from the annual meeting are valuable to the medical and scientific industry and it is important that they are brought into India.

Dr. Jain has close to 30 years of experience in fertility research and treatment and continues to advance this field. Dr. Sangeeta has had a brilliant career run with gold medals in academics and practice successfully from the past many years. After completing her MBBS and post-graduation in Obestrics and Gynaecology from King George's Medical College, Lucknow, she has been training with distinguished experts like Dr. R. Rajan and Dr. B. N.Chakravarty, the pioneers of India's first test tube baby at Institute of Reproductive Medicine.

She founded JoyIVF Clinic in New Delhi to maintain the set benchmarks in form of fertility services.

About JoyIVF Clinic:

Joy IVF Clinic,in East Delhi under brilliant guidance of Dr. Jain, has been able to achieve its aims with high rates of success. It has been able to help couples from all spheres of life toenjoy and celebrate the emotions attached to parenthood.

For more details, visit:

Joy IVF Clinic – Where dreams are born

Dr. Sangeeta Jain of JoyIVF Clinic participates in ESHRE 2017 in Geneva, Switzerland

Media Contact:Ms. Sucheta Sunderiyalmail@joyivf.com+91-8010790790JoyIVF Clinic

SOURCE JoyIVF Clinic

More:
Senior IVF Specialist Dr. Sangeeta Jain Participates in ESHRE 2017 in Geneva, Switzerland - PR Newswire India (press release)