Nanny state comes for the Impossible Burger and other meat substitutes – Washington Examiner

For health, environmental, and personal reasons, millions of Americans and even some fast-food burger connoisseurs are encouraged by the growth and increasing sophistication of the beef substitutes industry. But will old-school government pushback and a Bootleggers and Baptist-style pro-regulation coalition stall the growth of meat substitutes?

First, lets back up a bit and review the history of consumer regulation.

There was a time back in the 1970s when legislators let little escape their regulating pens, as they were so wholly dedicated in their effort to regulate away every real and imagined imperfection in human behavior. The Consumer Product Safety Commission, for example, wanted to outlaw one wooden Hickory Dickory Dock toy because when a child struck a mallet against it (as designed), it made too much noise.

In another egregious example of overreach, the Federal Trade Commission worried that consumers were just not smart enough to go without federal guidance when laundering and bleaching clothes. The agency issued rules requiring that labels filled with detailed instructions be attached permanently to garments and even to carpets and rugs. It went so far as to provide a glossary of words that could be used.

So, too, there were regulatory forays involving over-the-counter medicines that outlawed the use of such phrases as cures the common cold. After all, everyone knew there is no cure for a cold, even though self-medication can provide some relief. The regulators reasoned that anyone unwittingly buying such advertised products would be misled, evidently thinking Americans are too stupid to figure this out for themselves.

Indeed, the FTC became so fired up in its effort to give detailed consumer guidance that even the Washington Post called it the National Nanny and asked for some regulatory relief in a 1979 editorial.

During these regulatory heydays, I spent some time at the FTC. I learned that those who have the power to regulate also have the power to choose winners and losers. People in the policymaking playpen realized that regulation could be used strategically to expand markets or to raise costs for the rivals of politically influential businesses.

It was during this same period that, inspired by what I was observing, I developed my Bootlegger-Baptist theory for explaining the rise of regulation.

It was named after a dynamic, which can occur with local liquor laws, and it goes like this: Successful federal regulation frequently requires that two quite different interest groups work to support the same regulation. Bootleggers, are black-market business interests, which support prohibition due to the financial gain that comes from undermining their competition. Meanwhile, Baptists take the moral ground. Maybe they hope to make the world a better place for uninformed consumers. They also provide some validation for politicians and regulators.

As a case in point, consider again the FTC laundry-labeling juggernaut. The agency decided that some items of clothing should not be subjected to home laundering and wanted the associated label to say Professionally Launder Only. Producers of self-service, coin-operated, dry-cleaning equipment located in laundromats let out a howl. Meanwhile, the professional laundry industry was smiling.

The same thing happened when the agency determined that some fabric should be labeled, Do Not Bleach. Producers of safe bleach that can be used on sensitive fabrics were not happy. Even though that was then and this is now, there are some indications that the Washington nanny state is ready to strike again.

In December, Sen. Deb Fischer who just so happens to be a long-time member of the cattle industry introduced the so-called Real Meat Act. The Nebraska Republicans bill targets the rapidly-growing market for plant-based beef substitutes, products such as the Impossible Burger, which mimic meats appearance and taste. The legislation would codify a definition for beef and require that the words IMITATION MEAT be placed on product labels.

Noting her concern for consumers, and perhaps hoping to take some moral high ground, the senator said, I think we're seeing a number of fake food fads that are going on and we want to make sure that consumers know what they're buying. When you look at a lot of the plant-based meals that are being put out there, they're trying to piggyback on really, really good nutritious, safe beef. National Cattlemens Association President Jennifer Houston agreed, indicating that the industry merely wants a level playing field. (Shocker.)

Meanwhile, Jessica Almy of the Good Food Institute, which represents producers of plant-based food, indicates that no consumer complaints have been registered. She suggests that the whole effort is about protecting the conventional meat industry, not consumers.

Whats the lesson for 2020? Even at a time when the Trump administration is working almost feverishly to cut back existing rules while stifling new ones, certain regulations have powerful appeal and ready-made coalitions ready to turn them into reality. Could it be that officials on one side of Washington are pruning away rules while legislators on Capitol Hill are calling for more?

It wouldnt be the first time, nor will it be the last.

Bruce Yandle is a contributor to the Washington Examiner's Beltway Confidential blog. He is a distinguished adjunct fellow with the Mercatus Center at George Mason University and dean emeritus of the Clemson University College of Business & Behavioral Science. He developed the "Bootleggers and Baptists" political model.

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Nanny state comes for the Impossible Burger and other meat substitutes - Washington Examiner

The Circle is the Perfect Show for This Moment in Time – PRIMETIMER

We can see them, but all they know about each other is what they choose to share on social media. (Photo: Netflix)

The age of the social experiment on reality TV has hit a rough patch. Stalwarts of the genre like Survivor and Big Brother have become wildly inconsistent. The former throws too many twists into the mix, while the latter leans heavily on casting archetypes. The competition shows, which once promised real glimpses of human behavior, have become more interested in the game.

And even when those shows do get into social experiments these days, they usually butcher them so badly that you want them to stop. Survivor's recent failure in dealing with unwanted sexual advances dismayed and depressed fans, while pervasive racist and sexist behavior cast a pall over Big Brother 21, culminating in a fascinatingly dismal crowning for winner Jackson Michie. Point being: Whether they're actually trying to be social experiments or not, these shows are no longer suited to exploring human behavior in a reality TV context.

Instead, that mantle has been taken up by The Circle, Netflix's American adaptation of a UK format that beginson New Year's Day. The series, which will drop four episodes a week for three weeks, is like Big Brother in that it features players living in a building together. Where it differs, however, is that they never interact in person. Instead, the eight players (which, in a Love Island-esque fashion, are replaced by other players as the game goes along) interact solely through a social media network, called "The Circle."

Isolated in separate apartments and given multiple TV screens that are connected to The Circle, players must participate in social games, write profiles, upload photos, and chat with their fellow players. At the end of each cycle of gameplay, one player is Blocked, meaning they're eliminated and out of the game. If the idea of watching people talk to screens all day sounds boring to you, trust me, I thought the same until I found myself bingeing every episode of the series via screener in one day. It's an addictive gem of a show, one that really functions as a social game first and foremost.

Like Big Brother and Survivor, the ultimate purpose of the game is to reach the end. That means being well-liked enough to stay atop the social rankings players must rank all their fellow house guests every round but not so socially threatening that you become a target. Having to do this solely over text-based chat means saying all the right things, keeping in touch with everyone regularly, and staying apprised of who does and doesn't like who. The social games are fun, and do sometimes come with rewards, but there's nothing game-changing involved players live or die by their social strategy.

There's an extra wrinkle, though: Some players choose to play as catfish, misrepresenting their identities on The Circle. So there's a natural paranoia that permeates the game: Who is who they say they are, and who's lying to get ahead? It's a fear that feels all too real in the time of Instagram stalking and making friends on Twitter and Facebook. Moreover, it's a twist that would never work on Big Brother, utilizing The Circle's specific format to up the stakes.

What's most appealing about The Circleis the relatability, the idea that all of us are playing a version of this game in our daily lives. Unlike its predecessors, The Circle is the perfect reality competition show for this moment, with a remarkably savvy understanding of how social interactions work in 2019. Not every aspect of the show clicks there's some clunky pacing, especially in the first few episodes but once you plug into this network, you'll be addicted before you know it.

People are talking about The Circle in our forums. Join the conversation.

Kevin O'Keeffe is a writer, host, and RuPaul's Drag Race herstorian living in Los Angeles. Follow his musings and rantings on Twitter@kevinpokeeffe.

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The Circle is the Perfect Show for This Moment in Time - PRIMETIMER

Greys Anatomy Star Caterina Scorsone Gives Birth to Baby No. 3 With Husband Rob Giles – Us Weekly

Greys Anatomy star Caterina Scorsone announced the arrival of her third child with husband Rob Giles on Tuesday, December 31.

Arwen is here! the actress, 38, captioned two Instagram photos that showed the newborn cuddling with each of her big sisters, Eliza, 7, and Paloma, 3. Our family wishes you a happy new year, a happy new decade and a happy heart made new by love in every exquisite moment.

Scorsone, who plays Amelia Shepherd on the ABC medical drama, revealed in November that she was expecting baby No. 3, when she posted a Halloween-themed photo of herself, her musician husband and their two daughters dressed as the Addams Family along with the caption, Our Familys about to get even kookier. #pumpkinintheoven.

Fans of Greys Anatomy saw her character announce her pregnancy in the season 16 premiere episode earlier this year.

In March, Scorsone opened up about her daughter Paloma, who has Down syndrome.

My whole concept of what motherhood was had to shift, she said on the Motherly podcast.

When Paloma, who the family calls Pippa, was born, the Private Practice alum realized she was going to have some physical differences and some cognitive differences I didnt know what her capacity would be. It really did send me into a tailspin.

She questioned how to raise her baby: If my job is not to equip her to compete and dominate socially, or educationally, or physically or economically what is a mother? What is my job?

But after her initial reaction, Scorsone realized her primary responsibility is to keep her safe and make her feel loved.

Suddenly my understanding of my job as a mother completely distilled and opened, she continued, adding that it made her rethink the way she was parenting her eldest child.

I loved Eliza so much because she was so clever, and she was so beautiful and she was so funny but all those things were external qualities, Scorsone said. It forced me to realize that I was loving my other daughter and everyone, including myself, for absolutely the wrong reason. I was loving people for their external qualities and not for their essence.

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Greys Anatomy Star Caterina Scorsone Gives Birth to Baby No. 3 With Husband Rob Giles - Us Weekly

A look at the anatomy of the new Land Rover Defender – autoX

Does saying adios to the ladder frame mean that its the end of the road for an absolute legend? In Gaydon, they are convinced that its not they insist that the off-road ability of their most iconic car remains uncorrupted.

It begins quietly the criticism of the new Defender usually with a compliment. Its beautiful, no doubt. And then comes the kill shot, But its not really a Defender! Its becoming increasingly common to come across such comments on social media, and in automobile forums.

Its been over a month since the official presentation of the most iconic of Land Rovers, and the discussion surrounding it doesnt seem to cease. Gerry McGovern, the design head of the Land Rover, who fought really hard for new design innovation, jumped into this so-called controversy when he said, those who were die-hard fans of the old Defender probably wont buy the new one, revealing an important aspect of the strategic game of this Tata-owned English manufacturer to go fishing in a bigger lake rather than the small (niche) one afforded to it by the original model.

However, despite the larger target audience, there is something that Land Rover cant afford and thats jeopardizing the legendary off-road ability of its most iconic model. Moreover, its also a question of image if word were to spread that their toughest and purest off-roader has now become a fashionable car, suitable only for the urban jungle, it would put an end to the reputation of the entire brand.

But well reserve our judgment regarding its off-road abilities until such time that we get our hands on the new Defender. In the meantime, we can tell you all about the numbers at hand, what its made of, and everything thats underneath its shell. After all, a bit of rationality in the discussion never hurts, does it?

Now, we know that its not easy to completely discount emotion when talking about a model that coincided with the very foundation of the brand. We all know the story. Born from the idea of Maurice Wilks, technical director of Rover, who, in 1947, thought that a vehicle, not unlike Jeep, rugged and economic, could meet the demands of the British rural class exhausted by the war. And the result was a basic vehicle, which was presented at the Amsterdam Motor Show in 1948 and, of course, quickly went on to become a commercial phenomenon.

The reason behind its phenomenal success was simple it could literally take you anywhere and get you out of any difficult situation on any terrain. A combination of its ladder frame chassis, two rigid axles with semi-elliptical leaf springs, a body with aluminium panels, a four-cylinder 1.6-litre engine, producing 50bhp, combined with a four-speed manual gearbox, and all-wheel drive, it was simply called the Series 1 but it had all the foundations of the legend it went on to become after assuming its current name in the 1990s.

Ultra-rigid ShellWith the same name and essentially the same mechanical layout, although partially evolved, the Defender continued its journey until three years ago, when the regulations put a stop to its production, except for a special limited-edition series in 2018 the Defender Works V8 that was launched to celebrate the 70th anniversary of its birth.

However, the name remains today, even though a lot has changed. A new skin, but not without respecting its tradition, and underneath something that, in the eyes of enthusiasts, was completely untouchable the ladder-frame has now been replaced by a monocoque chassis.

The last old-fashioned English off-road vehicle couldnt resist the modern influence and now belongs to a family of vehicles the Discovery and Range Rover (except the Evoque) that share the D7 aluminium monocoque architecture, called D7x x stands for extreme, indicating the demanding and exacting tests that the machine has had to go through.

Well, according to Land Rover, this new platform has a torsional rigidity of 29kNm/degree, which makes it three times more rigid than a traditional ladder-frame chassis.

The new Defender has a maximum suspension articulation of 500mm (in the version with air suspension). However, it would be interesting to know the vehicles Ramp Travel Index or RTI, which is a measure of a vehicles ability to flex its suspension, or to put it simply, the extent to which a vehicle can advance with one wheel on a ramp before the other one breaks off the ground a value that Land Rover hasnt revealed yet.

What Land Rover, however, has revealed is that the Defender 2020 has the same maximum ascent/descent gradient of 45 as the old one. Meanwhile, the maximum side-slope gradient of the new Defender is 45 against the 30 of the older one. The Defender 2020 is 30mm wider (a total of 2,100mm) and a few millimetres lower, which also reduces the vehicles tendency to tip-over.

The repositioning of a few components, including the battery and cooling circuits, made it possible to keep the overhang short for the benefit of the characteristic angles. Here are the claimed numbers for the Defender 38 approach angle, 40 departure angle, and 28 ramp breakover angle (31 in the Defender 90), which are on par with the Jeep Wranglers 44 approach angle, 37 departure angle, and 28 of ramp breakover angle. Whats worth noting here is that the new Defender loses out to the old Defenders 49 approach, 35 departure (47 for the 90), and 30 ramp breakover angle.

Almost autonomousTo compensate for a few small physical limitations of the Defender 2020, the vehicle comes with the state-of-the-art Advanced Driver Assistance System or ADAS, which is a true innovation for an off-road vehicle. It also gets Terrain Response 2, which is the off-road gear management software package developed by Land Rover that now comes with new functions.

A touchscreen sits on the centre of the dashboard, which allows you to select various modes, depending on the surface (gravel, snow, rock, sand, etc.). The touchscreen also offers three settings to adjust throttle and transmission response, steering and traction control, and to manage the locking of the central and rear differentials.

Of course, the Defender 2020 comes with an Auto setting, suitable for novice off-road drivers, which allows the Terrain Response System to recognize the surface of the ground, using cameras and sensors, and automatically choose the most suitable off-road mode, without any input from the driver. In short, it democratises off-road driving.

The Defender also comes with ClearSight Ground View, which offers a clear view of the ground in front of the car on the screen, using front cameras as if the hood is transparent allowing you to see exactly where the wheels are positioned on the ground surface.

A new recordThe new Defender even has a Wade mode it can be selected from the Terrain Response menu which assists the driver in crossing a fjord by locking the differential and increasing the ground clearance, while the Wade sensing shows the depth of water.The maximum depth it can tackle, and rest assured its the last number that well cite, is 900mm, a record in itself, which the Defender shares with the Discovery. To put things in perspective, the Jeep Wrangler has a maximum wading depth of 750mm.

So, in the end, despite all the changes, will the new Defender do the same things the old one did? At Gaydon, they claim, it will do even more. But the kicker is that itll be a lot more civilized on the surface in which itll spend most of its time the tarmac!

The new Defender kicks up the dirt on a muddy track in Kazakhstan. Built on a monocoque for the first time ever, the new Land Rover has been subjected to very intense and exacting off-road tests in various parts of the world, including Moab a paradise for off-roaders in the Utah Desert of the USA.

The spartan rawness of the old Defender is just a memory, kept alive by details such as visible screws and an exposed magnesium crossbeam in the cabin. For the most part though, the cabin, dominated by a 10-inch touch screen, is refined and hi-tech.

ANATOMY OF AN OFF-ROAD VEHICLE

Unlike the path chosen by its high-profile competition the Jeep Wrangler and Mercedes-Benz G-Class the Defender abandons the ladder-frame chassis and adopts a modern self-supporting aluminium body, with independent suspension double-wishbones at the front and a multi-link at the rear, with coil springs in the standard version (air springs are optional). The latter offers greater travel and increases the off-road ride height by 75mm, but the adaptive dynamics system also improves handling on the asphalt, monitoring and analysing the movements of the body 500 times per second. Land Rover claims that the D7x platform offers a very high degree of robustness 6.5 tonnes of breakout load on the anchor points, 7 tonnes of vertical load on the suspension, 300kgs of static maximum load on the roof, and 168kgs of dynamic load. The new Defender is built, in the classic 90 and 110 versions (three and five doors, respectively), on a dedicated line in the Slovak factory in Nitra, where the Discovery is also assembled.

The Defender democratises off-road driving. Terrain Response 2 allows even rookie adventurers to experience real off-road driving. Above, the screens of the ClearSight Ground View (left) and the Wade sensing (right). Whats curious, however, are the choice of wheels the smallest is 255/70R18. But we think that the 255/75R17 could have been better suited to certain off-road conditions.

Riproduzione riservata

Also read -4x4 Genesis: Land Rover Series 1 + Defender + Discovery + Land Cruiser

Mercedes-Benz GLC vs Land Rover Discovery Sport vs BMW X3 vs Volvo XC60

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A look at the anatomy of the new Land Rover Defender - autoX

Grey’s Anatomy season 16 episode 10 title revealed; what’s it… – CarterMatt

Whats coming up onGreys Anatomyseason 16 episode 10? We know that this episode is airing on January 23. Also, we know that this is going to be a crossover withStation 19.

Want to get some more news when it comes toGreys Anatomyin video form?Then check out some of the latest below! Once you do that, subscribe to CarterMatt on YouTube and then also view our show playlist.

Also, why not go ahead and share a little bit of episode-title news right now? According to a report coming in per SpoilerTV, the title for the winter premiere is Help Me Through the Night. Given the crisis that is going on at Joes Bar, where characters are seemingly trapped inside and their lives are on the line, this makes a certain degree of sense. (For those wondering, theStation 19premiere is entitled I Know This Bar.

Through theGreys Anatomyseason 16 premiere, one of our primary hopes and expectations is that we get little opportunities to check in on some of the different characters and get a panoramic sense of life around the Grey Sloan Memorial Hospital. We know that Ben is in danger and Bailey is recovering from a miscarriage, and beyond that, Amelia has to figure out if she wants to tell Owen that he could be the father of her baby. Meanwhile, Jo has some important conversations to have with Alex while Meredith Grey needs to get used to being around Dr. Cormac Hayes.

Were sure that there are some more surprises twists and turns coming, so we cant even predict all of those just yet!

(As some of you out there know,Greys Anatomyepisode titles are based on songs Help Me Through the Night is a song that has been recorded a number of times, courtesy of a number of big-name artists. Its not just iconic and tied to a single person!

Related News Be sure to check out some more news on the series, including scoop on whats coming up next!

Be sure to share right now in the comments, and be sure to stick around for some other news. (Photo: ABC.)

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Grey's Anatomy season 16 episode 10 title revealed; what's it... - CarterMatt

Greys Anatomy Season 17: Premiere Date, Cast, Plot And Other Updates – The Digital Weekly

The new season will introduction will likely be the last Thursday in September 2020

Season 16 of Grays Anatomy is only starting. However, with all of the movements at Gray Sloan Memorial Hospital most importantly, Meredith Gray was ended in the wake of being caught for insurance distortion we understand what Grays fans are thinking at present: Is this the completion of the show?

Even though her characters future in Seattle is alluding to, Ellen Pompeo has officially energized her understanding through 2020, which means Grays Anatomy is delving in for the long stretch for one more season.

TBD. Given past seasons, the new season will introduction will likely be the last Thursday in September 2020. In case ABC continues with their TGIT lineup, the helpful sensation will be trailed by its sister to show up.

Per Pompeos latest game plan with ABC, the performer is set apart on for the seventeenth season. Valuable thing since ABCs diversion supervisor Kerry Burke explained that Grays Anatomy wouldnt continue without the shows lead on-screen character.

This comes just a single year after Pompeo referenced that she was scanning for a change. Ahead of season 16, the on-screen character uncovered to Entertainment Weekly that shes feeling like were landing toward the completion of the accounts that weve told and what we can tell.

Were hypothesizing that the majority of Grays fans contradict this thought. Given how that season 16 started with an impact (Meredith was ending from the crisis center! Amelia is pregnant!), its a shield to expect that the accompanying season will be comparable as earth-shattering.

As Vernoff puts it, the back and forth movement season is perplexed and stacked with catastrophe, job changes, and noteworthy moves in facility organization. Its hard for me to state who anyone should pull perhaps in help.

I trust its a human, tangled, complicated season, she uncovered to TV Guide. While the focal points are as yet dubious, Pompeo, who happens to be one of the shows producers, promises to continue relating to quality stories.

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Greys Anatomy Season 17: Premiere Date, Cast, Plot And Other Updates - The Digital Weekly

Breakthrough in Understanding Evolution Mitochondrial Division Conserved Across Species – SciTechDaily

Cellular origin is well explained by the endosymbiotic theory, which famously states that higher organisms called eukaryotes have evolved from more primitive single-celled organisms called prokaryotes. This theory also explains that mitochondriaenergy-producing factories of the cellare actually derived from prokaryotic bacteria, as part of a process called endosymbiosis. Biologists believe that their common ancestry is why the structure of mitochondria is conserved in eukaryotes, meaning that it is very similar across different speciesfrom the simplest to most complex organisms. Now, it is known that as cells divide, so do mitochondria, but exactly how mitochondrial division takes place remains a mystery. Is it possible that mitochondria across different multicellular organismsowing to their shared ancestrydivide in an identical manner? Considering that mitochondria are involved in some of the most crucial processes in the cell, including the maintenance of cellular metabolism, finding the answer to exactly how they replicate could spur further advancements in cell biology research.

In a new study published in Communications Biology on December 20, 2019, a group of scientists at Tokyo University of Science, led by Prof Sachihiro Matsunaga, wanted to find answers related to the origin of mitochondrial division. For their research, Prof Matsunaga and his team chose to study a type of red algathe simplest form of a eukaryote, containing only one mitochondrion. Specifically, they wanted to observe whether the machinery involved in mitochondrial replication is conserved across different species and, if so, why. Talking about the motivation for this study, Prof Matsunaga says, Mitochondria are important to cellular processes, as they supply energy for vital activities. It is established that cell division is accompanied by mitochondrial division; however, many points regarding its molecular mechanism are unclear.

This exciting new research describes how mitochondrial replication is similar in the simplest to most complex organisms, shedding light on its origin. Credit: Tokyo University of Science

The scientists first focused on an enzyme called Aurora kinase, which is known to activate several proteins involved in cell division by phosphorylating them (a well-known process in which phosphate groups are added to proteins to regulate their functions). By using techniques such as immunoblotting and kinase assays, they showed that the Aurora kinase in red algae phosphorylates a protein called dynamin, which is involved in mitochondrial division. Excited about these findings, Prof Matsunaga and his team wanted to take their research to the next level by identifying the exact sites where Aurora kinase phosphorylates dynamin, and using mass spectrometric experiments, they succeeded in identifying four such sites. Prof Matsunaga says, When we looked for proteins phosphorylated by Aurora kinase, we were surprised to find dynamin, a protein that constricts mitochondria and promotes mitochondrial division.

Having gained a little more insight into how mitochondria divide in red algae, the scientists then wondered if the process could be similar in more evolved eukaryotes, such as humans. Prof Matsunaga and his team then used a human version of Aurora kinase to see if it phosphorylates human dynaminand just as they predicted, it did. This led them to conclude that the process by which mitochondria replicate is very similar in different eukaryotic organisms. Prof Matsunaga elaborates on the findings by saying, Using biochemical in vitro assays, we showed that Aurora kinase phosphorylates dynamin in human cells. In other words, it was found that the mechanism by which Aurora kinase phosphorylates dynamin in the mitochondrion is preserved from primitive algae to humans.

Scientists have long pondered over the idea of mitochondrial division being conserved in eukaryotes. This study is the first to show not only the role of a new enzyme in mitochondrial replication but also that this process is similar in both algae and humans, hinting towards the fact that their common ancestry might have something to do with this. Prof Matsunaga concludes by talking about the potential implications of this study, Since the mitochondrial fission system found in primitive algae may be preserved in all living organisms including humans, the development of this method can make it easier to manipulate cellular activities of various organisms, as and when required.

As it turns out, we have much more in common with other species than we thought, and part of the evidence lies in our mitochondria!

Reference: Cyanidioschyzon merolae aurora kinase phosphorylates evolutionarily conserved sites on its target to regulate mitochondrial division by Shoichi Kato, Erika Okamura, Tomoko M. Matsunaga, Minami Nakayama, Yuki Kawanishi, Takako Ichinose, Atsuko H. Iwane, Takuya Sakamoto, Yuuta Imoto, Mio Ohnuma, Yuko Nomura, Hirofumi Nakagami, Haruko Kuroiwa, Tsuneyoshi Kuroiwa and Sachihiro Matsunaga, 20 December 2019, Communications Biology.DOI: 10.1038/s42003-019-0714-x

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This is How Cells in the Human Body Learn How to Count – News18

Researchers have given us a count of around 37.2 trillion cells in the human body. Each of these mammalian cells constitute a nucleus and a cell membrane.

And as revealed by cytologists, every cell is symmetrical to one another, and that there are 23 pairs of chromosomes found in most of humans. The reason behind this fascinating fact is due to the cell programming, in all probability.

As per this programming, each variety of cell strives to reach a particular, pre-determined target size; and in the process, it adjusts, readjusts itself from time to time assessing whether it has crossed or lagging behind that target. There are molecules that sense its own size and enable the human cell to maintain uniformity.

However, there are certain cells in order to carry out some specific tasks, break out of this uniformity matrix.

Johns Hopkins University School of Medicine researchers conducted on genetically engineered mice, have suggested that the cilia count is dictated by a process observed in non-mammalian species. Known to have appeared first on single-celled organisms, cilia are small hair-like, finger-like primordial structures that serve as motors sensing the environment by shifting the cell or antennae.

What makes these cells noteworthy is that while other cells create 1 cilium per cell, these advanced cells go about creating hundreds of cilia.

In an attempt to answer the burning question, how the multi-cilliated cells are so drastically different from the rest of the body cells, Andrew Holland (PhD), professor of molecular biology and genetics (at the Johns Hopkins University School of Medicine), discovered that cilias base, centriole, where organelles are attached, gets formed prior to cell division; thereby leading to 2-parent centrioles in each cell.

Deuterosomes get created by multi-cilliated cells, which serve as a copy machine.

Keeping this theory in mind, Holland conducted experiments, which surprisingly ruled out deuterosomes pivotal function in determining cilias number. His experiments also disproved the idea that centrioles absence would impact the cilias number; and showed centrioles can be created spontaneously just like in small flatworm planaria which experiences the same de novo generation of centrioles.

Upon delving deeper, Holland observed that there is an area rich with fibrogranular material in the cell, where centrioles are flocking together. It is this protein concentrated region in the cell, brimming with required elements to create centrioles, which might be responsible for ultimately determining the number of cilia getting created, suspects Holland.

In his opinion, deuterosomes act to mitigate pressure from the parent centrioles. By being free from the activity of creating new centrioles, the parent centrioles thereby get to carry out other necessary activities.

All the experiments helmed by Dr Holland, have been chronicled in Nature Cell Biology, as Dec 2.

Unearthing the mechanisms or causes governing the cilia number, can shed light on treatment of respiratory infection, infertility, hydrocephaly-- all cilia-related ailments.

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The health impacts of cell towers – Point Reyes Light

How are cell towers similar to DDT, an insecticide infamous for its environmental impacts? Its a good question. On Dec. 8, about 90 local residents asked this question and many more at an event to explore the health and environmental impacts of wireless technology. As new cell towers are being proposed in the area, interest was high, with standing-room only in the Point Reyes Community Presbyterian Church.

The event was sponsored by the West Marin Alliance for Human and Environmental Health, the Point Reyes Coalition for SafeTech and the Ecological Options Network. I spoke alongside Dr. Madga Havas from Canada and Ellie Marks of the California Brain Tumor Association.

I am a physician who has studied and developed policies for environmental toxins for over 25 years. When I learned of a proposal to place a cell tower on my daughters school 10 years ago, I dove into the research. What I learned is that wireless technology and infrastructure is a broad environmental and human toxin. We use and are increasingly surrounded by these devices: cell phones, laptops, smart watches, smart meters and internet routers. Unfortunately, we are told these devices are safe, that we do not really know if there is harm or that the research is inconclusive. Myself and over 250 expert scientists who have looked at this issue conclude the opposite.

To start with, the standard set by the Federal Communications Commission is based only on a single impact: heating of the tissues. This is like a cooking standard, and it ignores other biological effects. Nature and human biology are much more complex than technology. Humans evolved over millions of years in an environment with extremely low electromagnetic radiation. Our bodies use very tiny electrical signals that communicate within a labyrinth of molecules which are critical to the proper development of a fetus and to the healthy functioning of an adult.

In medical school, I learned about only a fraction of the thousands of dizzying interactions within and between cells that regulate reproduction, energy metabolism, the immune system, the gut, the brain and the nervous system. I learned that biology is both intricate and fragile, like a symphonic orchestra in which every instrument must be played perfectly. In studying toxic exposures, I learned that there can be different mechanisms at work that cause harm to our cells and biology.

One of these mechanisms is oxidation, which, like rust, causes aging and the breakdown of DNA, proteins, lipids and other critical molecules. The insecticide DDT causes oxidation, and antioxidants we consume counter this effect. The effect of oxidation on cells has been well studied; scientific literature connects oxidative cellular harm to inflammation and human disease. This mechanism does not involve heat injury.

When non-ionizing electromagnetic radiation is emitted from wireless devices, it passes through us and is variably absorbed in our bodies. The radiation is absorbed by water and blocked by metal. Of 100 peer-reviewed articles on radio frequency radiation and oxidation, 93 studies found a positive result, or resulting damage to DNA, lipids and proteins. This is not a thermal effect; it is a biological effect.

Dozens of studies have linked wireless radiation to sperm, ovarian and embryo harm, and to miscarriage. Neurologic injury is also a worry because studies show damage to nerve cells, the alteration of neurotransmitter levels, the opening of the blood-brain barrier (with large epidemiologic studies indicating memory impairment), behavioral changes and an increase in brain cancer.

Addiction to and the overuse of wireless devices is especially problematic for children. Six studies have demonstrated brain shrinkagein white and grey matterin those addicted to electronic devices. A new article in the Journal of the American Medical Association Pediatrics showed evidence of microstructural brain changes and brain shrinkage in children age 3 to 5 years who use an electronic device more than one hour a day.

Studies on cell towers show an increase in cancer in those living within 1,500 feet of towers; other studies show an alteration in stress hormones and blood abnormalities. A significant percentage of people also report non-specific or vague health symptoms, including headaches, fatigue, dizziness, nausea and insomnia when living close to cell towers. Electro-sensitivity is a real disease and more peoplefrom 3 to 18 percentare reporting vague symptoms when they use wireless devices.

Wireless radiation can also affect the health, behavior and migration of animals. Bees appear particularly sensitive, and plants and trees are also adversely affected. Precaution on all fronts is needed with the placement of cell towers, as the radiation they emit is constant. Once a large cell tower is in place, 5G small cells will follow. Cell towers become a permanent Trojan horse.

Cindy Russell, a plastic surgeon practicing in Mountain View, is the executive director of Physicians for Safe Technology. For more information, visit MDSafeTech.org.

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The health impacts of cell towers - Point Reyes Light

Bruker Corporation to Present at the 38th Annual JP Morgan Healthcare Conference – BioSpace

BILLERICA, Mass., Dec. 30, 2019 /PRNewswire/ -- Bruker Corporation (Nasdaq: BRKR) announced today it will participate in the 38th annual J.P. Morgan Healthcare Conference in San Francisco. Frank Laukien, Chairman, President & CEO and Gerald Herman, CFO will present on behalf of the company on Monday, January 13th, 2020 at 11:30 AM Pacific Time.

A live audio webcast of the presentation will be available on the Investor Relations section of the Company's website at https://ir.bruker.com . A replay of the presentation will be posted in the "Events & Presentations" section of the Bruker Corporation Investor Relations website after the event and will be available for 30 days following the presentation.

About Bruker Corporation (Nasdaq: BRKR)

Bruker is enabling scientists to make breakthrough discoveries and develop new applications that improve the quality of human life. Bruker's high-performance scientific instruments and high-value analytical and diagnostic solutions enable scientists to explore life and materials at molecular, cellular and microscopic levels. In close cooperation with our customers, Bruker is enabling innovation, improved productivity and customer success in life science molecular research, in applied and pharma applications, in microscopy and nanoanalysis, and in industrial applications, as well as in cell biology, preclinical imaging, clinical phenomics and proteomics research and clinical microbiology. For more information, please visit: http://www.bruker.com.

Contact: Miroslava MinkovaDirector, Investor Relations & Corporate DevelopmentBruker CorporationT: +1 (978) 663 3660, ext. 1479E: Investor.Relations@bruker.com

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SOURCE Bruker Corporation

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Bruker Corporation to Present at the 38th Annual JP Morgan Healthcare Conference - BioSpace