The Chris and Paul Show brings the funny to Steel City Improv – TribLIVE

Comedians Chris ONeill and Paul Valenti The Chris and Paul Show freely admit they are a couple of big kids.

Watching their videos and television performances bears out that claim. Using primarily facial expressions and body language, they deliver silly, laugh out loud physical comedy.

Referring to themselves as modern day vaudevillians, the two might bring to mind Laurel and Hardy, Buster Keaton or the television show The Kids in the Hall, depending on ones generation.

We draw from a lot of the old-time greats. Were basically like a live cartoon on stage, ONeill says.

Finalists on NBCs Bring the Funny, they clearly entertain judges Chrissy Teigen, Kenan Thompson and Jeff Foxworthy, even roping Teigen into their act in one episode.

You got all these laughs without saying a word and thats a special skill set. I couldnt stop laughing, I was beating the table, and thats what (Bring the Funny) is all about, Foxworthy says in a release.

The duo will perform at Steel City Improv in Pittsburgh for two shows 8 p.m. Feb. 7-8.

They also will hold a 2 p.m. Feb. 8 workshop at the Improvs alternate location, 6401 Penn Ave., Pittsburgh.

20 years of skits

The two began performing together after meeting in 1999 in Connecticut. They eventually teamed up and traveled from their homes into New York City to perform after Valenti called a club, pretending to be a manager and booking their act.

We were so excited to do shows in New York. On the train we realized we had no show prepared. We wrote our act on the train, ONeill says. They later moved to New York and began their careers in comedy through trial and error, they say.

Its called The Chris and Paul Show because its the two of them being themselves, Valenti says.

We are also very immersive. We use the audience, but we dont shame or embarrass them, he adds.

Inviting someone on stage turns that person, ONeill says, into the champions in the show.

They get an ovation. Its all in good fun, he says.

Bringing their own funny

The great thing about working with Paul is its a good balancing act. Paul is completely fearless, ONeill says.

Classical music fans, the two listen to Bach, ONeill says, and think, What would be funny to go along with this beautiful music?

Each audience brings a new dynamic to their show, ONeill says. You learn quickly how funny you are when you do shows for New York audiences.

After finding their voice, he says, they began approaching international festival organizers.

They are winners of awards including Best Newcomer Nominee, Edinburgh Fringe Festival; Best Actor in a Comedy (they tied), New York Television Festival; Best Sketch Comedy Duo, the INNY Awards; and Best Newcomer, the Montreal Comedy Festival.

Language is no barrier to audiences finding their comedy relatable.

Its human behavior. We had a group of kids (at one performance) who didnt speak English. I was watching them and they were just in awe of what we were doing. They started smiling and laughing. We feel like our act is universal, Valenti says.

Their Saturday workshop is open to anyone, performers or not, they say.

We like to strip (comedy) down to the bone and get to the root of whats funny, ONeill says.

Though the two use some words and music, they deliver most of their material sans dialogue. One of the scariest things for a performer or someone giving a speech is silence.

Embracing that silence opens up a whole new world of opportunities, they believe.

Mary Pickels is a Tribune-Review staff writer. You can contact Mary at 724-836-5401, [emailprotected] or via Twitter .

The Headshot Truck LLC

Connecticut comedy duo Chris ONeill and Paul Valenti will perform at Steel City Improv Feb. 7-8.

The Headshot Truck LLC

Connecticut comedy duo Chris ONeill and Paul Valenti will perform at Steel City Improv Feb. 7-8.

The Chris and Paul ShowWhen: 8 p.m. Feb. 7-8; workshop 2 p.m. Feb. 8Admission: $15 and up, workshop cost is $90Where: Steel CityImprov, 5950 Ellsworth Ave., Pittsburgh; workshop at 6401 Penn Ave., PittsburghDetails: 412-404-2695 or steelcityimprov.com

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Geek School: The art of playing dead – SYFY WIRE

Welcome to Geek School! This SYFY WIRE series provides practical lessons in writing, producing, and selling the nerdy projects of your dreams, with advice from some of the top creators and professionals in the business. In this lesson, we're talking about how to play dead convincingly.

Horror and sci-fi films, not to mention myriad episodes of the Law & Order franchise, are often littered with the corpses of victims of slasher stalkers, epic battles, and other unfortunate circumstances. Naturally, actors whose characters die have to go limp and convince us they are lifeless. At other times, prosthetic bodies can be used in place of real people, depending upon how ravaged their body is.

The trick is to make sure that the real actors look dead, especially during long takes. It's not as easy as it looks. Let's face it: Plenty of scenes have been marred by a supposedly deceased person breathing or twitching.

A good dead performance is something audiences take for granted, but a dicey one can pull them out of the realism of the scene. A great example is a circular pan shot in the entertaining 1972 film Raw Meat (starring Donald Pleasence with an appearance by Christopher Lee) about a cannibal roaming below the London Underground. A deceased man, eyes open, sits against a wall as the camera does a full 360-degree pan around the flesh eater's lair. When the rotating shot finally returns to the victim, he blatantly blinks.

There are aspects of living human behavior that are hard to control, like the twitching of eyelids or the pulsating of an artery. Some tricks can be used to work around these issues, such as specific camera angles, camera movement to show the dead body first before moving onto something else or even trying slow motion to get more out of the take. There are different factors at play.

"It depends on the level of dead we're talking about," notes Jovanka Vukovic, director of Riot Girls and "The Box" segment of XX. "Sometimes you can use a real actor and other times you have to use a dummy. Again, it depends on how you are making them dead. If you're blowing a character's entire head to smithereens then sometimes the most effective camera angle is the one that best captures the details of the f***ing mess flying at the screen."

Not every death is spectacular. Many are tranquil, and there are times that an extended take is needed and an actor must channel their inner corpse. The Method approach would not work here you can't actually die for your role so you need a good strategy.

One person with experience as a deceased character is filmmaker and actor Matthan Harris (The Inflicted, For We Are Many, the forthcoming Baphomet). He's a pro at death.

"I think the key to believably playing dead on screen is, first of all, to really let your yourself go release all tension and energy, and go completely limp," Harris instructs. "Then you'll need to take a deep breath just before the director says 'Action' and hold it for the duration of the shot until you hear 'Cut.' This way, you'll avoid being seen breathing during the take. You don't want to be the corpse whose stomach is clearly moving up and down."

"Actors are usually pretty good at holding their breath, but there are things they can't control like their heart beating," Vukovic says. "I've had to VFX paint out a jugular vein pulsing in a close up of a 'recently deceased person.' If there is an award for dead acting, however, it should go to The Autopsy of Jane Doe's Olwen Katherine Kelly, who played the cadaver. Her shallow breathing was so remarkably subtle it unnerved actors Brian Cox and Emile Hirsch, who sometimes forgot they were not working with a dummy."

Harris adds that if one is playing in a master shot that could run a few minutes long, he advises one to take "the shortest, shallowest breaths possible. It's also helpful to play dead in a position that is comfortable so that it's easier to do it for an extended period of time. However, if the scene requires you to be in a specific position such as lying in a specific angle against a wall, or leaning backward while bound on a chair then you'll just have to make it work."

He notes that it is easier to play dead with one's eyes closed. But if the scene calls for you to keep your eyes open, he offers a special tactic. "It helps to fix your eyes into a 'blind' state, in which you stare off into nothingness until your vision goes blurry," Harris says. "This will prevent you from accidentally looking at something and moving your eyes. I recommend avoiding any caffeine or other stimulants that day, so that your eyelids are completely still during the shots. I love coffee as much as the next guy, but you don't want your closed eyelids to twitch uncontrollably when you're supposed to be stone dead."

Playing dead becomes complicated during the process of "death" itself. "I worked with Munro Chambers on Riot Girls, and I had to run him through with a machete," Vukovic recalls. "He spent a lot of time effortlessly choking, gurgling, gasping, and lying motionless on the ground without blinking. It was his fourth time being killed that year." (As with other businesses, it does help to hire an experienced working stiff.)

Then there is the slow death.

"When we were filming the cannibalism Christmas dinner scene for XX, I had to put Natalie Brown in this wild contraption for hours because too many parts of her body were a special effect that needed to be carved away and partially eaten," Vukovic says. "She was a real trooper. We got through that with a lot of period jokes, patience, and sips of Gatorade."

Towering actor Derek Mears has ratcheted up an impressive resume of characters, including Jason Voorhees and Swamp Thing. He died on ER, got blown up in Pirates of the Caribbean, and got his head bashed in by a rock in The Hills Have Eyes Part II. (Some guys have all the fun.)

Mears will be the first to admit that playing dead can be pretty tough. "The weird thing about it is people think about how reality is from what they've been conditioned to from TV," Mears explained in an earlier interview. "People think that when you die you fall down and close your eyes and you're dead, whereas in reality a lot of times your eyes will be open or your mouth will still be open or you'll be frozen in position or your arms will lock up. It is tough because, depending upon how long the scene is, you're trying to hold your breath or move your stomach minimally. [But] you have to breathe."

He revealed that he has a special "Ninja technique" where he tries to slow his heart rate down so he does not breathe as much. He focuses on relaxing his body as much as possible. It's a simple but effective technique, which can be helpful when many directors have literally instructed him to "play dead" and say nothing further.

"I remember on Cursed, they were shooting a scene above me while I was lying dead on the ground," Mears recalled. "I had to be stuck in the werewolf suit for a long time, and at one point I actually fell asleep. I was there forever, and I remember waking up in the middle of a take and thinking, 'Oh my God! Was I asleep?' I could hear dialogue but couldn't see through the mask at the angle I was at. I didn't move, and I don't think anybody caught on that I was actually asleep."

It looks like Mears stumbled upon the ultimate solution to playing dead: Knock yourself out. Literally.

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Geek School: The art of playing dead - SYFY WIRE

Five Podcasts That Will Help You Stay Relevant, Gain the Advantage and Win: In Other Words Be More Human in an Age of Technology Take-over -…

by Tamara Ghandour

I often get asked questions such as, How do I add value now that this software can do part of my job? or is there a role for me now that Artificial Intelligence is taking over the world? My answer is always this:

You could find yourself on the fast path to irrelevancy or you can adapt, elevate your game, and leverage the digital disruption thats inevitable in all our worldsall you have to do is be more human. The choice is yours.

And to make it easier once you make the choice to be more human in the age of digital disruption, here are 5 podcasts that will help you separate yourself from the pack, stand out in a cluttered world, and deliver tremendous value in your work and life.

Hidden Brain: The most powerful tool we have is right between our ears yet most of us have zero idea how to truly use it. Not because we arent intelligent, but because that intelligence happens by magic behind the black curtain. But, as Hidden Brain shows us, the real power is in understanding how this magical gelatinous thing works. Hidden Brain by NPR helps you understand unconscious patterns that shape your human behavior, your choices, and direct your relationships. Recently I listened to the episode Emotional Currency.

Inside LaunchStreet with Tamara Ghandour: In the age of digital disruption, Tamara reminds us that our greatest competitive advantage is to be more human. At the forefront of human-centered innovation, Tamara will help you unlock the key to gaining the competitive advantage through the power of innovation so you can perform at your peak, ignite innovation, and have a strong, valued voice in the world. A combination of neuroscience, behavioral psychology, 25 plus years of experience brought together in a really personal, tangible and accessible to all kind of way. Im a little biased on this one of course. Recently, I listened to the episode How To Get Unstuck.

The Moth: A collection of real-life stories told without notes that will fill you with hope and connection. Short, poignant, and powerful, the stories presented on The Moth range from love and regret to passion and opportunity. They will make you feel deeply connected to humanity in a way Facebook, Instagram, and texting simply cant. I love The Moth because, in a time where the news is dominated by negativity and the latest and greatest disruption, The Moth will remind you that emotion, communication, and storytelling are still relevant in todays complex times. Recently I listened to the episode War, Barbie Dream House, Coco and a Nekkid Man.

Legendary Life with Ted Ryce: Interviewing the top minds in nutrition, fitness, and performance, Ted brings you more than just an eat less, workout more perspective to health. As a longevity champion, he delves into everything from keto, to stress management to communication. Lets face it, good physical and mental performance is the foundation for having the energy you need to perform at your peak, rise up and win. Recently I listened to the episode Why Everything You Think About Aging May Be Wrong With Dr. Charles Brenner.

HBR Ideacast: A mix of the most brilliant minds in business and leadership, HBR Ideacast brings you insights and tactics into elevating your game in work and life. This podcast covers a range of topics ranging from how to create new habits to how to delight customers. And because it comes from Harvard, they get to bring the leading voices in a range of topics that impact how you perform in work and life. Recently I listened to the episode The Right Way To Form New Habits With Author James Clear.

Photo by NeONBRAND on Unsplash

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Tamara Ghandour of GoToLaunchStreet is a TED speaker and entrepreneur. From building and running multimillion dollar businesses, advising Fortune 500 like Disney, Procter and Gamble and RICOH on fostering innovative ideas and people. Tamaras life is about breaking through the status quo for game-changing results, and thats what her keynotes, online programs and assessments can do for you.

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Five Podcasts That Will Help You Stay Relevant, Gain the Advantage and Win: In Other Words Be More Human in an Age of Technology Take-over -...

User and Entity Behavior Analytics Market 2020 Global Industry Analysis By Share, Key Company, Trends, Size, Emerging Technologies, Growth Factors,…

User and Entity Behavior Analytics Market

The report on the Global User and Entity Behavior Analytics Market covers historical market trends, current market dynamics, market valuation by segmentation as well as region, country-level analysis for every segment, key players market share analysis, competitive landscape and supply chain analysis.

Market Overview

User and entity behavior analytics (UEBA) is an effective cybersecurity process that detects internal security threats, curbs down financial fraud and identifies target attacks on enterprises IT infrastructure. It analyses and records anomalous human behavioral patterns, deploying statistical techniques, algorithms, and machine language to monitor cybersecurity threat. The benefit UEBA offers is that it keeps track of users and entities within the system, instead of depending on security events or monitoring device. Reports and logs, file, flow, and packet information are the in-system assistance to record data. The potency of UEBA process is the main factor which is predicted to drive the market growth in the forecast period.

Today when the world is evolving into a digital era, an increase in demand for real-time analytics owing to the growing cybersecurity threat is boosting the user and entity behavior analytics market growth. Moreover, an increase in awareness of UBEA solutions among enterprises is leveraging market broadening.

The user and entity behavior analytics market expansion is likely to experience resistance due to the following mentioned factors. Enterprises cut down on the budget for user and behavior analytics solutions and shortfall on advanced insider threatsinformation are possible constraints on the user and entity behavior analytics market growth.

Market Research Future reports (MRFR) that the user and entity behavior analytics market is anticipated to register a CAGR of 41.73% during the forecasted period of 2017-2023 and valuation to scale up to USD 1,178.19 million by 2023 end.

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Segmental Analysis

The user and entity behavior analytics market study done by MRFR is segmented based on type, deployment type, vertical and region.

Based on the type, the user and entity behavior analytics market is bifurcated into solution and services.Based on deployment type, the market is segmented into on-premises and cloud.

Based on vertical, the user and entity behavior analytics market is segmented into BFSI, government, healthcare, IT and telecommunication, energy and utility, retail, and others.

Based on region, the market is segmented into North America, Europe, Asia-Pacific, and the Rest of the World (RoW).

Key Players

Noteworthy companies profiled by MRFR in the user and entity behavior analytics market are Splunk Inc. (US), Microsoft Corporation (US), Varonis Systems, Inc. (US), Exabeam, Inc. (US), Observe IT (Israel), Niara Inc. (US), Sqrrl Data, Inc. (US), Bottomline Technologies, Inc. (U.S.), and Rapid7 (US). The other key innovators in the market are Securonix (US), Bay Dynamics (US), Gurucul (US), and Dtex Systems (US).

The market key players are magnifying their presence in the market by launching new products or entering into partnerships, agreement, and collaboration with other giant companies.

Regional Analysis

North America is expected to have a ascendancy over other regions in the User and Entity Behavior Analytics Market in the upcoming years. Increase in adoption of UEBA solutions in the region is influencing the market growth. With a firm technical base, the US, Mexico, and Canada are investing a good amount in research and development to come up with great innovations in UEBA solutions that will deliver maximum benefit to UEBA solutions to customers.

Increase in ownership of smartphone and an increase in the use of web applications are expected to prompt the need for adopting security solutions in the Asia Pacific region. These factors are proliferating the user and entity behavior analytics market growth in the region.

Industry Update

April 2019: Safe-T Group Ltd announced the launch of the user and entity behavior analytics solution, named Safe-T Telepath. Safe-T Telepath is designed to avert malicious and unauthorized users to organizations internal services from accessing its data.

Intended Audience

About Market Research Future:

At Market Research Future (MRFR), we enable our customers to unravel the complexity of various industries through our Cooked Research Report (CRR), Half-Cooked Research Reports (HCRR), Raw Research Reports (3R), Continuous-Feed Research (CFR), and Market Research & Consulting Services.

MRFR team have supreme objective to provide the optimum quality market research and intelligence services to our clients. Our market research studies by Components, Application, Logistics and market players for global, regional, and country level market segments, enable our clients to see more, know more, and do more, which help to answer all their most important questions.

In order to stay updated with technology and work process of the industry, MRFR often plans & conducts meet with the industry experts and industrial visits for its research analyst members

Media ContactCompany Name: Market Research FutureContact Person: Abhishek SawantEmail: Send EmailPhone: +1 646 845 9312Address: Market Research Future Office No. 528, Amanora Chambers Magarpatta Road, Hadapsar City: PuneState: MaharashtraCountry: IndiaWebsite: https://www.marketresearchfuture.com/reports/user-entity-behavior-analytics-market-7033

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User and Entity Behavior Analytics Market 2020 Global Industry Analysis By Share, Key Company, Trends, Size, Emerging Technologies, Growth Factors,...

Gerald Fink awarded the Genetic Society of America’s Thomas Hunt Morgan Medal – MIT News

Gerald R. Fink,Whitehead Institute founding member and former director and professor of molecular genetics in the MIT Department of Biology, has been awarded the 2020 Thomas Hunt Morgan Medal, bestowed by the Genetics Society of America (GSA). The award recognizes a distinguished scientist who has a lifetime achievement in the field of genetics and a strong history as a mentor to fellow geneticists. TheGSA is an international community of more than 5,000 scientists who advance the field of genetics.

Fink, who is also the Herman and Margaret Sokol Professor at Whitehead Institute, is a former GSA president and the 1982 recipient of the GSA Medal. In honoring him with the Thomas Hunt Morgan Medal, GSA is recognizing Finks discovery of principles central to genome organization and regulation in eukaryotic cells.

This year, the Morgan Medal will also be awarded to David Botstein, chief scientific officer for Calico Labs and professor emeritus of molecular biology at the Lewis-Sigler Institute for Integrative Genomics at Princeton University, in recognition of his multiple contributions to genetics, including the collaborative development of methods for defining genetic pathways, mapping genomes, and analyzing gene expression.

These awards to Gerry and David are richly deserved and I am so pleased they are being honored together, says Whitehead Institute DirectorDavid Page. Gerry Fink has fundamentally changed the way researchers approach biological problems, and his many discoveries have significantly shaped modern science. David Botstein has helped drive modern genetics, establishing the ground rules for human genetic mapping. Page has worked closely with both men: beginning his research career as an investigator in Botsteins lab, and collaborating with Fink for more than three decades at Whitehead Institute.

The medals will be formally presented to Fink and Botstein at the Allied Genetics Conference in April.

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Gerald Fink awarded the Genetic Society of America's Thomas Hunt Morgan Medal - MIT News

World Cancer Day: Going back to the basics The genetics of cancer – Firstpost

We have all heard of the term gene and DNA, but little do we know about the impact of changes in them known commonly as genetic mutations. Most cancers are associated with these changes in specific genes which are sub-units of the genetic material, DNA. In this era of modern medicine & treatment, certain genetic mutations have been identified to be responsible for several diseases including cancer and targeting such mutations play a major role in the overall management of the disease, to improve the quality of the life and cure.

In the past two decades, there has been an increasing number of cancer cases in India. According to the Globocan 2018 data, about 1.16 million new cancer cases in India were reported with close to 7.9 lakh deaths. In India, the cancer subtypes in descending order are breast cancer (14 percent), lip/oral cavity cancers (10.4 percent), cervical cancer (8.4 percent), lung cancer (5.9 percent) and stomach cancer (5 percent) followed by others.

Most cancers are associated with changes in specific genes which are sub-units of the genetic material DNA.

The question that arises that How genetic testing would help in understanding genetic mutation and its relation to cancer/s? The simple answer to this question is, whatever one asks for. Genetic testing provides varied answers, starting from predisposition, and events before onset of cancer to treatment planning and monitoring as well as detection of early relapse/recurrence.

How can the genetic information related to cancer, be decoded even before the cancer onset? Well, the presence of certain gene mutations increases the chances of developing cancers drastically. These cancers are known as hereditary cancers, and the process is known as hereditary risk assessment. Understanding genetic mutations can help one understand whether there are increased chances of developing cancer. For example, any woman is at a 12 percent lifetime risk of developing breast cancer, in general population, but if there is a presence of harmful BRCA1 mutation, in a given individual due to inheritance, this risk can go as high as 70 percent.

Once cancer has developed, there are various ways in which these genetics tests can prove handy. Understanding genetic mutations can help the oncologist diagnose and differentially diagnose cancer subtypes in a more informed manner. Further certain genetic mutations help in understanding if the cancer progression will be aggressive or not. For example, in case of a leukaemia subtype: chronic lymphocytic leukaemia (CLL), the presence of IGHV gene mutation indicates that cancer wont progress aggressively. In medical terms it is known as good prognosis. On the other hand, there are some gene mutations that indicate poor prognosis of cancer as well.

Coming to the most known of application of genetic testing, we all have heard of what is called targeted treatment. Presence of certain gene mutations help the oncologists target the cancer as far as treatment is concerned. For example, in lung cancer, there are various classes of drugs that are based on gene mutations, such as EGFR inhibitors, which have a better effect on EGFR mutated lung cancers.

Certain genetic mutations help in understanding if the cancer progression will be aggressive or not.

Other applications of genetic testing include assessment of the treatment response for a given drug, also to detect the early recurrence in a periodic manner by a non-invasive procedure to check for cancer-specific mutations in the plasma of the blood sample, also known as liquid biopsy testing

Like all other subjects, cancer genetics is also something where India has certain unique features. There are multiple research papers that mention that in lung cancer, the prevalence of EGFR mutations is higher in south-Asian, particularly Indian population, as compared to the western populations. This provides an added advantage of treating these patients with targeted therapy for killing the specific cancer cells, thus avoiding the side effects associated with conventional chemotherapy. Hence understanding the mutation status of EGFR gene becomes imperative in case of lung cancers.

Similarly, there is a subclass of breast cancer called triple-negative breast cancers (TNBC), where there is an absence of receptors known to fuel breast cancer growth- Estrogen, Progesterone and Her-2/Neu gene. This is one of the most aggressive subtypes of breast cancer, where there are to targeted therapies available so far, and the standard of care remains conventional chemo-radiotherapy/surgery. Considering its aggressive behaviour the recurrence rates are very high in this subtype of cancers, and nearly 20 percent of these women are BRCA1/BRCA2 mutation carriers. As far as India is concerned, the triple-negative breast cancers incidence is higher in India (30 percent) as compared to the western population (12-17 percent), and have a poorer prognosis and survival (60 percent: 5 years age-adjusted survival) as compared to the Caucasian population (80 percent: 5 year age adjusted survival).

Talking about BRCA1 mutated breast cancers, one particular mutation, DelAG, is considered to be founder mutation in Ashkenazi Jewish community. Founder mutations is when a genetic alteration is observed with high frequency in a group that is or was geographically or culturally isolated, in which one or more of the ancestors was a carrier of the altered gene. In our experience, we have seen this founder mutation in Indian sub-population as well over and above Ashkenazi Jewish community.

In conclusion, genetic testing is aimed at providing clarity and insights about a persons cancer to the Oncologists that helps them make an informed decision. An increasing number of Oncologists have adopted genetic testing as an important tool for diagnosis and treatment planning of cancer and its management. Our constant effort is aimed to ensure, maximum number of cancer patients get benefitted by this technology in the society.

Dr Vidya Veldore is a principal scientist for Oncology at MedGenome Labs Ltd.

Updated Date: Feb 04, 2020 17:32:40 IST

Tags :Cancer,Cancer Day. World Cancer Day 2019,Cancer Patients,Diagnosis Of Cancer,DNA,Gene Mutations,Genes,Genetics Of Cancer,Genetics Tests,Oncologists,Oncology,Types Of Cancer,World Cancer Day

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World Cancer Day: Going back to the basics The genetics of cancer - Firstpost

Adam Rutherford: taking on racism with the help of genetics – Times Higher Education (THE)

There were several reasons why geneticist Adam Rutherford, an honorary research fellow at UCL, felt the time was right to publish a book titled How to Argue with a Racist.

One was a political climate, in Britain and beyond, where nationalism appears to be on the rise. There were signs even in the way people now responded to hisown heritage.

A couple of years ago, he told Times Higher Education, my Wikipedia page was changed to describe me as a British Indo-Guyanese scientist. While that is effectively accurate, I have never described myself as such and have no Indian or Guyanese cultural input. I think of myself as from Ipswich.

Furthermore, a huge recent rise in genetics ancestry kits has had the effect of reinforcing some ideas about biological essentialism which we were trying to erase from genetics,added the science broadcaster, whose media appearances include his position as presenter of BBC Radio 4'sInside Science.

There were also factors relating to Dr Rutherfords own discipline and institution. When he arrived at UCL at the age of 18 as a student, he writes, he was enrolled in the Galton Laboratory, which was once called the Galton Eugenics Laboratory, and was taught by the Galton professor in the Galton Lecture Theatre.

My entire field of human genetics is based primarily on the work of Francis Galton, Dr Rutherford said, and thus on a science built by racists in order to demonstrate the racial superiority of white men. It was through setting up the National Eugenics Laboratory at UCL that Galton laid the foundations for what is now the genetics department that I am still a member of, he continued.

Although Dr Rutherford felt no ambiguity about saying that Galton was a scientific genius: much of genetics, statistics and behavioural psychology is built on the work which he did in the late-19thand early 20th century, he was also unequivocally racist. A UCL inquiry, looking into the connections with eugenics of Galton, mathematician Karl Pearson and Egyptologist Flinders Petrie, should announce its findings soon.

Genetics, in Dr Rutherfords view, has now fortunately put its past behind it and is indeed a crucial tool in the battle against racism. There is now a vanishingly small number of geneticists and evolutionary biologists who [dispute] that genetics has clearly demonstrated that race is not a biologically meaningful categorisation, he said. It was a beautiful irony that the science built by Galton on racist premises had also proved to be the science which demonstrates the fallacy of his ideas.

Yet, as someone who constantly engages with the public, Dr Rutherford was well aware of a massive disconnect between what we are saying within the walls of the academy and what people think. His book is designed to provide ammunition to challenge the views not only of hard-line white supremacists, but also your slightly racist uncle and even basically well-intentioned people who say black people are better at sport or Jews are better at intellectual pursuits.

In addressing some of the common assumptions about race, Dr Rutherford started with the broad point that literally everybody is descended from everybody else.

He continued: We are really bad at understanding how family trees actually work. After a few generations, they become enormously matted webs. There are no pure ancestries, no pure lineages.

Yet it remained true, Dr Rutherford admitted, that nobody has seen a white man in the final of the 100-metre sprint in the Olympics since 1980. So what could be said to people who point to such facts and claim that they reveal, as Dr Rutherford put it, a natural ability among those descended from the enslaved to be good at explosive-energy sports?

If that argument was right, he said, where are such people in sprint cycling or swimming, which has featured one African American in the history of the Olympics? Similar arguments could be used against those who attributed the striking presence of Jews among composers and performers of classical music to innate talent, while ignoring cultural factors and other genres such as hip hop and jazz.

Even whensuch notions were seemingly used in a positive sense, Dr Rutherford went on, we must keep in mind links to a long history of offensive stereotyping.

He pointed, for example, to a study looking at several thousand comments in the media about elite athletic success. These referred to innate physical abilities for a black athlete and hard work, intelligence and industriousness for a white elite athlete. Such stereotypes are just baked into our culture.

Adam Rutherfords How to Argue with a Racist: History, Science, Race, and Realityis published by Weidenfeld & Nicolson on 6 February.

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Adam Rutherford: taking on racism with the help of genetics - Times Higher Education (THE)

A Court Tried To Force Ancestry.com To Open Up Its DNA Database To Police. The Company Said No. – BuzzFeed News

Ancestry.com, the largest DNA testing company in the world, was served a search warrant to give police access to its database of some 16 million DNA profiles, but the company did not comply.

Ancestry received one request seeking access to Ancestrys DNA database through a search warrant, the company revealed in its 2019 transparency report released last week. Ancestry challenged the warrant on jurisdictional grounds and did not provide any customer data in response.

The warrant came from a court in Pennsylvania, the company told BuzzFeed News by email, adding: The warrant was improperly served on Ancestry and we did not provide any access or customer data in response. Ancestry has not received any follow up from law enforcement on this matter.

For months, legal experts who follow investigative genetic genealogy have expected search warrants to be issued to Ancestry and its main competitor, 23andMe, which has about 10 million DNA profiles in its database. Both companies have publicly vowed to defend their customers genetic privacy, and say they will fight efforts to open up their databases to searches by police.

Investigative genetic genealogy is a new method used to solve crimes. It involves searching for genetic profiles that partially match DNA from crime scenes and then building family trees from these relatives to find a suspect. Until now, only two databases used by genealogy enthusiasts to research their family histories GEDmatch, originally set up by hobbyists but now owned by the forensic genetics company Verogen, and the database run by FamilyTreeDNA have been open to search requests from police.

Finding criminal suspects through genetic genealogy is a numbers game: The more profiles you have to search, the more likely you are to find a reasonably close relative.

GEDmatch contains about 1.3 million profiles and Family Tree DNA has around 1.1 million. So if cops were to gain access to the much larger databases operated by Ancestry or 23andMe, it would make solving cases much easier.

After the April 2018 arrest in California of Joseph James DeAngelo, alleged to be the infamous Golden State Killer, there was a boom in investigative genealogy. But in May 2019, cops hit a partial roadblock when GEDmatch announced that its users would have to opt in to make their profiles visible to searches by the police. Only about 1 in 6 users have since done so.

At that time, Paul Holes, a retired investigator with the Contra Costa County district attorney's office, who led the team that solved the Golden State Killer case, said he expected warrants would be issued to search GEDmatchs database and to access the genetic data held by the larger companies.

Of course there are going to be legal battles, Holes told BuzzFeed News. It would not surprise me, years down the road, if this could be a US Supreme Court issue.

Holes' predictions have so far proved spot on. In October, the New York Times revealed that a homicide detective with the Orlando Police Department had obtained a warrant to search GEDmatch, which quickly complied. Ancestrys new transparency report reveals that the big companies are now under pressure to open up their databases too.

23andMe told BuzzFeed News that it had received no warrants to search its database as of the end of 2019. The company is expected to update its own transparency report in the next couple of weeks.

We carefully scrutinize all law enforcement requests, and have never provided any customer information to a law enforcement agency, nor do we share customer data with any public databases or with entities that may increase law enforcement access, 23andMe told BuzzFeed News by email.

MyHeritage, which is based in Israel and has more than 3.75 million DNA profiles in its database, said that it had also not received any warrants to search its database and would similarly fight any that were received. Our position is that MyHeritage does not cooperate with law enforcement, company spokesperson Rafi Mendelsohn told BuzzFeed News.

The coming legal tussles are likely to center on the meaning of probable cause, which historically has meant there is a particular reason to conduct a search to help solve a crime. Arguing that a database containing genetic information on millions of people is so large that it is highly likely to help solve most violent crimes stretches that definition, some legal experts argue.

If statistical probability standing alone is sufficient to define probable cause, then probable cause is going to be virtually meaningless in an era of big data, Natalie Ram, a legal scholar at the University of Maryland who studies genetic privacy, told BuzzFeed News.

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A Court Tried To Force Ancestry.com To Open Up Its DNA Database To Police. The Company Said No. - BuzzFeed News

Terrace Global Announces Genetics Supply Agreement With Apollo Green for Acquisition of Genetics and Importation Into the European Union – Yahoo…

Highlights:

Terrace Global Inc. ("Terrace Global" or the "Company") (TSXV:TRCE) is pleased to announce that it has entered into a genetics supply agreement (the "Genetics Supply Agreement") with Apollo Green Inc. ("Apollo Green") whereby the parties have entered into an exclusive relationship with respect to the acquisition and importation of high-THC genetics for the Companys medical cannabis operations in Portugal.

Terrace Global has commenced the process to acquire the requisite starting materials for the first phase of its greenhouse facilities in Portugal, which will be comprised of approximately 65,000 square feet of greenhouse facilities, a 5,000 square feet of E.U. GMP processing and drying facility and a 3,300 square feet administrative building.

Pursuant to the Genetics Supply Agreement, Terrace Global will be acquiring the following genetics: Chem Stallion (15-25% THC, 0.5-0.1% CBD), Twisted Grape (15-25% THC, 0.5-0.1% CBD) and Apollo Skunk (15-25% THC, 0.5-0.1% CBD). These genetics will add to Terrace Globals existing inventory of high CBD genetics which were acquired from Colorado and used in its outdoor cultivation in Uruguay.

"We are pleased to be working with Apollo Green to develop our genetics inventory with a view to focusing on high-THC strains that we expect to be well received by the European Union medical cannabis market participants. Apollo Green has an extensive library of genetics that include a diverse set of market leading strains and cross-breeds," commented Francisco Ortiz von Bismarck, Chief Executive Officer of the Company. "Being able to source these genetics is an important milestone in the development of European operations. Without quality genetics, there is no pathway to success in the burgeoning E.U. medical cannabis industry."

Apollo Green has been accumulating an extensive library of high-THC genetics and has benefited from its relationship with Ed Rosenthal. Mr. Rosenthal is a Global Advisor to Apollo Green and is a leading cannabis horticulture authority, author, educator, social activist and legalization pioneer.

"Terrace Global is building a world-class cultivation facility in one of the most attractive countries from a regulatory and climate perspective. We will be working closely with the Company to see how these genetics perform by leveraging our extensive cultivation expertise," commented Tyler LeBlanc, Chief Executive Officer of Apollo Green. "This is a meaningful partnership for us as we seek to grow our genetics and plantlet business globally. Terrace Global is the ideal partner given its extensive experience and international footprint in Uruguay, Portugal and Spain."

The Genetics Supply Agreement is subject to various conditions precedent, including the issuance of the applicable export and import permits from the regulatory authorities in Canada and Portugal.

About Terrace Global

Terrace Global is a multi-country operator (MCO) led by experienced cannabis entrepreneurs focused on the development and acquisition of international cannabis assets. Terrace Globals focus is on federally legal jurisdictions with existing domestic demand, low cost inputs and approved for exportation. Terrace Globals existing asset platform consists of: (1) a 33.75% indirect equity interest in one of the currently two recreational cannabis operations in Uruguay; (2) 100% of Oransur, S.A., a Uruguayan company producing high CBD hemp in Uruguay; (3) 100% of Terra Nova Produo e Comercializao de Produtos Natuis e Farmacuticos, Lda, a Portuguese company with a pre-license issued by INFARMED for the cultivation, importation, and exportation of medical cannabis in Portugal; and (4) 100% of Pharmabinoide S.L., a Spanish company producing and commercializing hemp in Spain. MariMed Inc. (OTCQX:MRMD), a multi-state cannabis operator in the U.S., dedicated to improving the health and wellness of people through the use of cannabinoids and cannabis products, owns approximately 6% of Terrace Global.

About Apollo Green

Apollo Green was among the first wave of Canadian businesses to submit an application to Health Canada for a cannabis cultivation and sales license. In July 2019, Apollo Green was granted three licenses for standard cultivation, standard processing and federal medical sales. Apollo Green currently supplies premium genetic solutions and superior plantlets to Cannabis producers globally, specializing in reducing risk, space, costs, and time to its B2B customers, in a state of the art fully operational facility about 20 minutes east of downtown Ottawa.

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FORWARD-LOOKING STATEMENTS

This news release contains certain forward-looking statements, including, but not limited to, statements about the Companys future plans and intentions. Wherever possible, words such as "may", "will", "should", "could", "expect", "plan", "intend", "anticipate", "believe", "estimate", "predict" or "potential" or the negative or other variations of these words, or similar words or phrases, have been used to identify these forward-looking statements. These statements reflect managements current beliefs and are based on information currently available to management as at the date hereof.

Forward-looking statements involve significant risk, uncertainties and assumptions. Many factors could cause actual results, performance or achievements to differ materially from the results discussed or implied in the forward-looking statements. These factors should be considered carefully and readers should not place undue reliance on the forward-looking statements. Although the forward-looking statements contained in this news release are based upon what management believes to be reasonable assumptions, the Company cannot assure readers that actual results will be consistent with these forward-looking statements. These forward-looking statements are made as of the date of this news release, and the Company assumes no obligation to update or revise them to reflect new events or circumstances, except as required by law.

Neither the TSXV nor its Regulation Services Provider (as that term is defined in the policies of the TSXV) accepts responsibility for the adequacy or accuracy of this release.

View source version on businesswire.com: https://www.businesswire.com/news/home/20200129005855/en/

Contacts

Terrace Global Inc.Francisco Ortiz von Bismarck, CEO and Directorinfo@terraceglobal.ca http://www.terraceglobal.ca

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Terrace Global Announces Genetics Supply Agreement With Apollo Green for Acquisition of Genetics and Importation Into the European Union - Yahoo...

Cancer is genetic, early detection can help cure it: Sonali Bendre – Yahoo India News

Nargis Dutt Foundation held awareness event on World Cancer Day in Mumbai. Sonali Bendre took part in the programme. Speaking at the event on cancer she encouraged people to go for early detection if their families have cancer background. "Huge part of cancer is genetics. The more data you have on cancer, the more the doctors can help you. What in India we lack is data. Anyone who has cancer in their family, go and get yourself tested. Most important cancer is curable if detected early. Genetic testing is important," said Sonali Bendre.

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Cancer is genetic, early detection can help cure it: Sonali Bendre - Yahoo India News