Human Behavior

What kind of a beast are Residential Proxies? – PC-Tablet

Like most proxies, residential proxies act as an intermediary between a users device and the internet. They transfer requests from the user to the web and responses back from the web to the user. The sites that the user is trying to access will only detect the proxies identity and not the users. Generally, users will require a proxy server to:

So what kind of a beast are residential proxies? Before we look at what makes them unique, what are they? Residential proxies are actual residential IPs distributed by internet service providers to individuals/homeowners.

Basically, your ISP will give you a new IP address each time you move and connect your internet to a new location. Each residential IP address is connected to a dedicated device (mobile or desktop). It also contains information about the network, location, and ISP of the device.

What makes residential IPs special is that the servers perceive them as IP addresses of real people. If you would like to learn more details about residential proxies, you should dig in deeper, but the basic information is provided in this article. Restrictive sites that generally ban certain IP addresses will not block residential IPs because they look genuine. Heres how they benefit individuals and businesses with their unique qualities:

Web scraping is necessary for businesses today. They need to maintain their competitive advantage by gathering important competitor information from the web. However, this information is so much that they cant do it manually. Residential proxies are the perfect tool for large scale web scraping.

Although users can access restricted websites with residential proxies, these sites are constantly checking the user behavior for any strange activity. Lets assume you are trying to scrape 50 pages from a site with high-level, anti-scraping measures.

After scraping the first few pages, the server will detect repetitive unhuman activity. At this point, it might present you with a CAPTCHA or block your IP.

Residential proxy networks prevent web servers from detecting any unhuman user activity by imitating real human behavior. These networks contain various residential IP addresses which rotate after each request. Businesses can then scrape all the information they require without restriction.

Fraudsters have mastered the art of faking ad traffic. Real people are not seeing these ads and businesses are losing a lot of money in the process.

Competitors can also use this to damage their reputation. Residential proxies are an effective way to verify these ads, improve ad performance, detect ad fraud and anonymously check out the landing pages of advertisers.

For travel fare aggregators, collecting travel data is tough. Data sources like travel agencies, train companies, bus companies, and airline companies have stringent security checks and they will block any bot-like activity. This is where the legitimacy of residential proxies comes in, enabling aggregators to collect and compare different travel fare prices, time tables, and other data.

Popular sneaker brands will sometimes release a new limited edition product. For sneakers in particular, who doesnt want to own a limited edition pair of Adidas or Nike footwear?

The problem is that they only make a few pairs. Imagine millions of people eyeing 10,000 pairs of sneakers. The chances of owning one pair are slim to none unless you use residential proxies.

Residential proxies will help you bypass any geographical location restrictions imposed by these brands, so you can access the sites no matter where you live. Also, you can use several residential proxies to stand in line for you without being detected. The more you use, the better your chance of owning these popular kicks.

Residential proxies support several SEO tools and allow you to improve your business performance by optimizing your site effectively. When you scrape competitor information, you can access the keywords they use and discover their sources of traffic. Residential proxies also help you to create useful links.

Many users still use free proxies to access the web anonymously and access geographically restricted content but dont realize that its not as secure as they think.

You might be able to mask your IP address from the website youre accessing, but not from the proxy server. Basically, its like youre handing over your IP address to the proxy server for an opportunity to use theirs.

Dedicated residential proxies are generally more secure and provide you with a high-speed reliable connection. With residential rotating proxies, also known as residential backconnect proxies, your IP address can change every 5 to 10 minutes.

Residential proxies might be similar to other proxies in such a way that they provide anonymity, can bypass blocking mechanisms and access geo-restricted content. However, to answer the question What kind of a beast are residential proxies? you should look at their unique applications. Residential proxies are the only go-to proxies for web scraping and buying limited edition sneakers online.

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What kind of a beast are Residential Proxies? - PC-Tablet

Human Behavior

Opportunities for the At-Home-Parent – The Good Men Project

Thanks for coming. I know that this isnt your favorite thing, my wifes Big Boss said at her work office party. He couldnt have been more wrong.

As an at-home-parent, I dont get invited to many fancy parties. Most of the parties I attend involve an uncomfortable amount of snot and hotdogs. On occasion, there is beer, which is nice but I have to drink it through a juice straw.

Not here, though. Not at an awesome work party with other adults where no one wears a diaper. Well, if they do I dont want to know about it.

There are a lot of man buns though, just saying.

I can see why he thinks I dont like coming to these things. In the past, Ive written about them. Those awkward moments that accompany any plus one at a spouses party. I dont speak the lingo, I have no idea who Debra is in accounting, and if there is an office romance Im probably going to squeal on that person strictly because I didnt know it was on the down-low.

I also accidentally called my wifes Big Boss a terrible person at once. Regrettable, but I did get a very well-read piece out of it. In fact, it remains one of the funniest things Ive ever written.

But I love coming to the work parties because of the opportunities. So many opportunities.

As a humor writer, this place cannot be matched. This is what we call in my business a target-rich environment of human behavior. There are so many man buns that I giggle as I make my way across the room. Jokes write themselves.

Theres an open bar too and at some point, those 90s beats are going to drop, and with it the inhibitions of the younger staff as they forget they are in a work environment. At this point, Im really here just to document what I experience.

Its an opportunity for me to meet a lot of the people who helped get my writing off the ground. I have fans that I am forever grateful for. They shake my hand and bring up pieces that I had no idea someone read. Its humbling and awesome all at the same time.

At times, Im hugged. You have no idea how much that means to a writer, and I get the opportunity to soak it all in. Inside my head, I wonder what vision they have of me from my words and if it matches the pudgy bald guy they see in person. I almost want to apologize.

I get the opportunity to eat amazing food. There are no hotdogs or Mac N Cheese. The tacos are fancier than most of my clothes. There are meatballs on little cute sticks. There is something called a chicken lollipop and its delicious.

Most importantly though, its all cooked by someone else. You want to make sure an at-home-parent has a good time? Feed them and let them know someone else is going to do the dishes. Somedays, even a supermax prison sounds good to us.

I get the opportunity to hear music that has nothing to do with a childrens YouTube star. Its almost soothing. I recognize the beats blasting from the speakers near the DJ booth. His set up reminds me of Lite Brite. I wonder if he could punch the buttons to make a sunflower. For a moment, I consider going over there and showing him how. Im kinda a big deal in the Lite Brite game.

I get the opportunity to have adult conversations. I listen and around me, people talk about grown-up things. Books and movies, pop culture and politics, contracts and future plans. No one is discussing the most recent parent outrage or injustice, or at the very least, the problems that Paw Patrol is currently facing. God bless those dogs.

For an evening, Im in the adult world at a place that I have no right to be. Its nice. I look good in my sweater. I consider dancing with the interns as Ice Ice Baby blares over the loudspeakers.

I get the opportunity to experience the unexpected. The Big Boss gets on the P.A. and makes an announcement. He gives credit to those that have given them a great year. He highlights their growth. He compliments their hard work and dedication.

And then he does something unexpected. He thanks the significant others that support his staffs occasional late nights so they can do what they do. I get to experience the inclusion of the plus one. I eat a chicken lollipop to celebrate.

He didnt have to do that, but he did. He owes me nothing, in my mind. But to him, he does and its a sign of good leadership. Hes the opposite of terrible. That is my professional humorist opinion.

I get the opportunity for the greatest set up ever.

Outside, we get to watch two firetrucks roll-up. There is a fire at an electrical junction near the parking lot. Flames shoot high in the dark night so that we get to experience a replay of sunset. My wife glows next to me with her smile. The rest of the staff watch the firemen drag the hose out of the truck and hook it to the water main. I can smell ozone.

I tell my wife to stand close to me, and I take a picture with her. Shes smiling brighter than the fire behind us. She gorgeous, and I know Im lucky. Mainly, because as I text my daughter, I know that Im going to lay down a great dad joke.

Hey, honey! I text my daughter. Guess what?

What, she texts back in that unnatural speed of a teenager.

I send the selfie I took with my wife with the fire in the background.

This party is lit!

It may be the greatest dad joke I have ever laid down. The OMG I get back from my daughter confirms it.

So no, Mr. Big Boss, I dont hate coming to my wifes work parties. I love seeing my wife unwind with her coworkers. I love how much you care about them. I love to see the march of the man-buns to the dance floor when that 90s beat drops.

I love firetrucks in the background of a perfect picture, giving me the perfect dad joke, next to my perfect wife.

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Opportunities for the At-Home-Parent - The Good Men Project

Human Behavior

Taking the Ted stage to Cathy: Pitt alum finds success in resilience – University of Pittsburgh The Pitt News

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John Daniel, a West End native and 1979 Dietrich School of Arts and Sciences alumni, spoke Sunday in the Cathedral about how students can rewrite their definition of success.

Grace Giglio | For the Pitt News

John Daniel, a West End native and 1979 Dietrich School of Arts and Sciences alumni, spoke Sunday in the Cathedral about how students can rewrite their definition of success.

Grace Giglio | For the Pitt News

Grace Giglio | For the Pitt News

John Daniel, a West End native and 1979 Dietrich School of Arts and Sciences alumni, spoke Sunday in the Cathedral about how students can rewrite their definition of success.

Pitt alum John Daniel laid down in 2015 to receive a heart transplant which would extend his life for a minimum of 10 years. He stood four years later to give a TED Talk on the power and experience of intentional thought.

I had this picture in my head, Daniel said in the TED Talk. I saw myself on a bicycle all dressed with my helmet, doing a long bike ride in some exotic location. That got me through all the pain. The discomfort. Just having that vision in my head And so, the thing is, when you face something that seems daunting and overwhelming, youve got to have a picture of you on the other end.

Daniels TED Talk, Everything Will Be Alright, offered viewers a glimpse into his rise from poverty, the loss of his wife and the experience of undergoing a heart transplant. The Pittsburgh native and 1979 Dietrich School of Arts and Sciences graduate came to the 35th floor of Pitts Cathedral of Learning Sunday morning to talk to students about his perspective on success and cultivating a positive mindset.

Raymond Davis, the charitable relationship manager of the Division of Philanthropic and Alumni Engagement, suggested that he appear as a speaker at the Honors College after watching Daniels TED Talk and getting to know him.

I thought he was just a fantastic example of someone who took their education and ran with it. He looked for opportunities and worked hard, Davis said.

At the event, Daniel focused on the four basic factors to which he credits personal and professional success self-awareness, perspective, adaptability and resilience. Careful attention to these processes, he said, is what has led him to success and ultimately maintains his positive outlook.

Growing up, Daniel learned from his mother how to balance the chaotic and dynamic lifestyle that they shared. He moved 10 separate times as a child, he said, coupled with frequent trips to and from hospitals to combat health issues.

I came out of that with some sense of the ability to be in control of my circumstances, Daniel said.

Working as the executive vice president and chief human resources officer for First Horizon National Corporation, Daniel said he finds pride in teaching employees the ways in which they can gain control over their own circumstances.

According to Daniel, heightened self-awareness is an effective tool in developing rational thought and emotional intelligence. In the workplace, he said he frequently uses feedback as a strategy to raise employees self-awareness.

This idea of intrapersonal awareness, which I call self-awareness, is really important, Daniel said. [It] is your ability to understand your moods and behaviors and their impact on others. Reflection is key in developing the skill of self-awareness.

In Daniels experience, the largest obstacle in gaining self-awareness and perspective is a negative mindset.

The brain has a negative bias. So when something happens, the first question is why, Daniel said. Growing up, I wasnt automatically fighting the system, I was trying to understand the system.

Maintaining productive habits and seeking perspective now comes as second nature to Daniel, but only in retrospect. Productivity and positivity are attributes he believes are built with consistent and applied practice and must be practiced through the best and worst of times.

Fluctuations in social environments produce variations in human behavior that are reflective of the human ability to adapt to the unknown. The ability to adapt, he said, corresponds with resilience which he defines as the capacity to rebound from trauma.

Resilience, in some ways, is a product of our personality, Daniel said. It is not a trait like agreeableness and consciousness. It is a mental process that you can teach. The most important thing is to face an obstacle and to reflect on the inner voice in your head. You can rewire your brain through intentional thought.

Cassidy Dinsmore, a first-year student intending to major in human resources, attended the event to hear from a seasoned professional in the fields of HR and business. She found what John had to say to be a good complement to her intended course of study at Pitt.

It was an interesting validation of what I am learning here will be useful towards what I am doing in the future, Dinsmore said. Within business, HR is sometimes seen as lesser. So, its very interesting to hear from someone who has been so successful in HR and in the business field.

Daniel defines his success in measures of emotion. He said he is happy with family and friends, proud to be an active member of his community and excited to go to work everyday and share his expertise with others.

I still have setbacks! Daniel said. You have to accept the fact that it may take an hour, a day, a week or longer to build a growth mindset. It is important to think you can constantly grow and learn.

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Taking the Ted stage to Cathy: Pitt alum finds success in resilience - University of Pittsburgh The Pitt News

Neuroscience

Neuroscience Antibodies and Assays Market 2020-2024 | Technological Advances to Boost Growth | Technavio – Business Wire

LONDON--(BUSINESS WIRE)--Technavio has been monitoring the neuroscience antibodies and assays market and it is poised to grow by USD 1.36 bn during 2020-2024, progressing at a CAGR of 8% during the forecast period. The report offers an up-to-date analysis regarding the current market scenario, latest trends and drivers, and the overall market environment.

Technological advances has been instrumental in driving the growth of the market. However, high development cost of neuroscience antibodies might hamper market growth. Request a free sample report

Neuroscience antibodies and assays market 2020-2024: Segmentation

Neuroscience antibodies and assays market is segmented as below:

product

Geographic segmentation

To learn more about the global trends impacting the future of market research, download a free sample: https://www.technavio.com/talk-to-us?report=IRTNTR40305

Neuroscience antibodies and assays market 2020-2024: Scope

Technavio presents a detailed picture of the market by the way of study, synthesis, and summation of data from multiple sources. Our neuroscience antibodies and assays market report covers the following areas:

This study identifies advances in neuroscience instruments as one of the prime reasons driving the neuroscience antibodies and assays market growth during the next few years.

Neuroscience antibodies and assays market 2020-2024: Vendor Analysis

We provide a detailed analysis of around 25 vendors operating in the neuroscience antibodies and assays market, including some of the vendors such as Abcam Plc, Bio-Rad Laboratories Inc., Cell Signaling Technology Inc., F. Hoffmann-La Roche Ltd., GenScript Biotech Corp., Merck KGaA, Rockland Immunochemicals Inc., Santa Cruz Biotechnology Inc., Tecan Group Ltd. and Thermo Fisher Scientific Inc. Backed with competitive intelligence and benchmarking, our research reports on the neuroscience antibodies and assays market are designed to provide entry support, customer profile and M&As as well as go-to-market strategy support.

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Neuroscience antibodies and assays market 2020-2024: Key Highlights

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Technavio is a leading global technology research and advisory company. Their research and analysis focus on emerging market trends and provides actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions. With over 500 specialized analysts, Technavios report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavios comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios.

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Neuroscience Antibodies and Assays Market 2020-2024 | Technological Advances to Boost Growth | Technavio - Business Wire

Neuroscience

Three Ways to Change Your Parenting in the Teenage Years – Greater Good Science Center at UC Berkeley

Wow. Ugh. Thats amazing!

This is the usual wide-eyed response when people hear that I have four teenagers. Sometimes people grimace, like the mere thought of it is a bitter pill. They are thinking, I know, that teenagers are hard, which, of course, they can be. Everyone assumes I must be insanely busy, or maybe just a little insane, and that raising four teenagers must be nearly impossible.

These thoughts occur because many teenagers tend to be either terribly disorganized, requiring constant nagging, or tightly wound, perfectionistic, and in need of constant therapy. Theres also all that new neuroscience showing, unfortunately, that the brain regions that help humans make wise choices dont mature until kids are in their mid 20s, and that many potentially life-threatening risks become more appealing during adolescence while the normal fear of danger is temporarily suppressed. Knowing these things can make it hard for us parents to relax.

Though teenagers can be hard to parent, the good news is that parenting teenagers is in many ways a hell of a lot easier than raising little kids. For this to be the case, however, our parenting needs to shift. Here are the three big shifts that parents of teenagers need to make to survive their kids adolescence.

When our kids are little, we have to manage pretty much every aspect of their lives. We set bedtimes, plan meals, and make doctors appointments. We arrange carpools and make all major decisions: where they will go to school, if they will go to camp, and where well go on vacation. And when our kids are little, for the most part, they appreciate having involved and loving parents. Its great having someone else manage your calendar and get you to your activities (mostly) on time.

But once kids reach adolescence, they need to start managing their own lives, and they do tend to fire us as their managers. Parents who are too controllingthose who wont step down from their manager rolesbreed rebellion. Many kids with micromanaging parents will politely agree to the harsh limits their parents set with a yes, sir or a yes, maam attitude, but then will break those rules the first chance they get. They dont do this because they are bad kids, but because they need to regain a sense of control over their own lives.

The answer, according to neuropsychologist William Stixrud and long-time educator Ned Johnson, authors of The Self-Driven Child, is to hand the decision-making reins over to our teens. You read that right: By adolescence, we parents need to (take a deep breath and) let them make their own decisions about their lives. Its not that we never say no anymore. Nor do we stop enforcing our family rules. Its that we start to involve teens more in creating the rules, and we let them make their own decisionswhich they are going to do anyway.

Letting our kids become the primary decision makers does NOT mean that we become permissive, indulgent, or disengaged. It does mean that the qualityif not the quantityof our support shifts. We give up our role as their chief of staff and become more like life coaches. We ask questions, and provide emotional support.

Itd be great if we parents could just download information to our teenssay, about sex and drugsand know that they were going to use that information to make good decisions.

But giving teenagers a lot of information isnt an effective way to influence them anymore. Interesting research on this topic shows that what is effective for elementary school childrengiving them information about their health or well-being that they can act ontends to be mostly ineffective for teenagers.

This is because adolescents are much more sensitive to whether or not they are being treated with respect. The hormonal changes that come with puberty conspire with adolescent social dynamics to make teenagers much more attuned to social status. More specifically, they become super touchy about whether or not they are being treated as though they are high status.

In the teenage brain, the part of themselves that is an autonomous young adult is high status. The part of them that is still a kid who needs our support is low status. They might be half independent young adult, half little kid, but they are hugely motivated to become 100 percent autonomouseven if they do know, on some level, that they still need our support and guidance.

When we give our adolescents a lot of information, especially when it is information that they dont really want or that they think they already have, it can feel infantilizing to them. Even if we deliver the information as we would to another adult, teenagers will often feel disrespected by the mere fact of our instruction.

So, when its time to bring up the topic you want to influence your teen about, speak as you would to someone with the highest possible social statussomeone you really, really respect. (I have to literally imagine that person in my head, and then imagine both the tone and the words I would use with that person.) Remember, if your teen feels disrespected, nagged, spoken down to, pressed upon, or infantilized, all bets are off.

Remember what you used to talk about with your kids before they hit puberty? There are days when Id give anything to just be able to talk again about favorite foods and favorite colors and the tooth fairy. It isnt that every conversation was easy when they were young, but I rarely felt the kind of discomfort I now feel while talking to my kids about things like sexor even their college applications. What starts as a casual conversation can quickly become an emotional minefield. Its hard not to let our own agendas creep in. And it can be really hard to manage our own big feelings about things.

Talking with teenagers about their lives can be stressful. But teenagers today are dealing with some really hard stuff, and we parents need to create safe spaces for our teens to talk about the hard things.

This takes a lot of courage. The simplest way to increase our ability (and, frankly, willingness) to have uncomfortable conversations with our teens is to practice doing it in baby steps. Instead of thinking about having a big talk, broach a difficult topic in short observations and simple questions. Let teens lead; our real value comes when we listen rather than instruct. Even when we have a lot to say, its more important to give them a chance to speak, to work out what they are thinking in a low-risk environment. Practice staying calm despite the discomfort. Keep taking deep breaths. Keep relaxing your shoulders. Notice your discomfort, and welcome it. Its nothing to be afraid of.

As hard as it might be for us to watch, our teenagers are going to make mistakes. When they do, our anxious over-involvement wont help. What will help, though, is our calm presence. This is more good news, because it is far more enjoyable to practice calm presence than it is to freak out.

Above all, well do well to remember that their lives are their lives. Its their journey, not ours. Our role is not to steer them through life like we would marionettes, but rather to help them feel seen, and to help them feel safe. For that, we need only to coach instead of manage, listen instead of instruct, and breathe through our discomfort.

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Three Ways to Change Your Parenting in the Teenage Years - Greater Good Science Center at UC Berkeley

Neuroscience

New to America and Facing a Rare Condition, Patient Credits UK for Regaining Ability to Walk – UKNow

LEXINGTON, Ky. (Feb. 12, 2020) Being unable to walk and unable to provide for his family is not the American dream Gregorie Mbuyi imagined when moving his family to Kentucky from the Democratic Republic of Congo in 2015.

I was feeling shocked, explained Mbuyi with the help of a translator.

Shocked because the pain and discomfort he initially likened to heartburn were aggressively spreading through his abdomen and down his right leg he lived like this for about two years. The husband and father of five losing the ability to walk on his own, eventually also lost his ability to work.

While I was sick, life was very difficult. My wife was working double. She worked in the day and at night. He remembers feeling helpless sitting at home while longing to work and make life better for his family. Also, adding to that feeling of helplessness was the fact that he had zero answers after seeing roughly 20 different doctors and specialists.

Mbuyi made the move to America to create a story of new opportunities for his family. The beginning chapters of that story filled with unexpected and life-altering challenges. However, a visit to UK HealthCare's Kentucky Neuroscience Institute in November 2018 quickly changed that course.

I always ask my patients about how their symptoms are affecting their life. That is when I heard from him that he is not able to work and that he was the only bread-earning member in a family of seven," said Dr. Zain Guduru, neurologist and assistant professor in the University of Kentucky College of Medicine. "I felt bad for him and his family. At the same time, I wanted to get to the bottom of this issue. I remembered seeing one other similar case three years ago..

Due to that prior case three years ago, Dr. Guduru had a strong suspicion he was once again looking at a rare disorder known as stiff limb syndrome. Stiff limb syndrome is a neurological disorder that also has features of an autoimmune disease. The condition is characterized by muscle rigidity in the trunk and limbs.

Often people with stiff limb syndrome have antibodies that attack glutamic acid decarboxylase (GAD) in the spinal cord. GAD is an enzyme present in synapses in the central nervous system. It synthesizes an endogenous chemical called GABA and it decreases the firing of the neurons. Based on the symptoms of stiff limb syndrome, this disease is an analog to tetanus, he said.

Guduru ran a few tests during Mbuyis initial visit. One of those was to check for the anti-GAD antibodies that attack the spinal cord. The results were new for the neurologist, They were elevated to a number I had never seen before.

A treatment plan was developed and quickly set in motion. The 52-year-old started medication and was admitted to the hospital for three days of infusion. That treatment plan proved successful and only weeks later, at his first follow up visit, Mbuyi walked without assistance.

He also could bend his knees with ease and complete physical therapy. I saw a happy face and enthusiasm to show me that he can walk without difficulty or pain or stiffness in his muscles," Guduru said. "Gregories significant response to treatment made me feel happy for him and felt proud to diagnose this rare case."

Today, Mbuyi is once again working and providing for his family. Im happy. My family is happy. Their new life in America is also back on track.

Right now, life is better than before, said Mbuyi.

Guduru says Mbuyis story brings immense satisfaction to the work that goes on at UK. I was very happy to see him walk again, see him able to go back to work and to hear him say his whole family is happy now," he said. "In the end, it was a goosebumps moment when he said, I am so thankful to UK and my whole family would like to thank UK.

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New to America and Facing a Rare Condition, Patient Credits UK for Regaining Ability to Walk - UKNow

Immunology

Vir Biotechnology Identifies Two Antibodies That Bind to the Spike Protein of 2019-nCoV, Newly Named as SARS-CoV-2 – Yahoo Finance

SAN FRANCISCO, Feb. 12, 2020 (GLOBE NEWSWIRE) -- Vir Biotechnology, Inc. (VIR), a clinical-stage immunology company focused on immune approaches to treating and preventing serious infectious diseases, today announcedthat it has identified two monoclonal antibodies (mAbs) that bind to SARS-CoV-2 (previously known as 2019-nCoV), which were originally found because they bind and neutralize the original SARS-CoV. The antibodies target the SARS-CoV-2 spike protein in the region that the virus uses to enter cells through the cellular receptor ACE2. Infection with SARS-CoV-2 causes the newly named disease, Covid-19.

We are in the process of assessing neutralization with a pseudo-virus, said George Scangos, Ph.D., CEO of Vir. In addition, we are working with international partners to assess the capacity of these antibodies to neutralize the live virus, SARS-CoV-2.

The company is moving ahead with research to determine if its antibodies, or additional antibodies that it may be able to identify, can be effective as treatment and/or prophylaxis against SARS-CoV-2. To that end, the company is exploring collaborations with a number of other companies and governmental agencies. Amongst these are specific efforts at accessing manufacturing capacity globally.

We are pleased that, using the same platform that was used to isolate mAb114 which has proven to be active against Ebola, we have quickly identified antibodies with potential biological activity against SARS-CoV-2, said Herbert Skip Virgin, M.D., Ph.D., Chief Scientific Officer, Vir. We are working as rapidly as possible and look forward to sharing more information as we have it.

Vir identified these antibodies from an existing library of 20 fully human antibodies that bind and neutralize related coronaviruses, such as SARS-CoV and coronaviruses that infect animals. This library was built through a robust method for capitalizing on unusually successful immune responses naturally occurring in people who are protected from, or have recovered from, infectious diseases, including those caused by rapidly evolving and/or previously untreatable pathogens.

Antibody-based therapies are different from vaccines and have distinct attributes that may make them potentially valuable, particularly in pandemic settings:

Vir is investigating other approaches to identify additional potential therapies for SARS-CoV-2. In addition to testing these two antibodies, the company is also exploring the isolation of new antibodies specific for this virus using its antibody technology platform. These efforts may allow additional approaches to address this rapidly emerging public health epidemic.

About Virs Antibody PlatformVir has a robust method for capitalizing on unusually successful immune responses naturally occurring in people who are protected from, or have recovered from, infectious diseases. The platform is used to identify rare antibodies from survivors that have the potential to treat and prevent rapidly evolving and/or previously untreatable pathogens via direct pathogen neutralization and immune system stimulation. Vir engineers the fully human antibodies that it discovers to enhance their therapeutic potential. This platform has been used to identify and develop antibodies for pathogens including Ebola (mAb114, currently in use in the Democratic Republic of Congo), hepatitis B virus, influenza A, malaria, and others.

About Vir BiotechnologyVir Biotechnology is a clinical-stage immunology company focused on combining immunologic insights with cutting-edge technologies to treat and prevent serious infectious diseases. Vir has assembled four technology platforms that are designed to stimulate and enhance the immune system by exploiting critical observations of natural immune processes. Its current development pipeline consists of five product candidates targeting hepatitis B virus, influenza A, human immunodeficiency virus and tuberculosis. For more information, please visit http://www.vir.bio.

Forward-Looking StatementsThis press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as may, will, expect, plan, anticipate, estimate, intend, potential and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) are intended to identify forward-looking statements. These forward-looking statements are based on Virs expectations and assumptions as of the date of this press release. Each of these forward-looking statements involves risks and uncertainties. Actual results may differ materially from these forward-looking statements. Forward-looking statements contained in this press release include statements regarding the companys efforts to neutralize the SARS-CoV-2 virus and identify additional potential therapies for SARS-CoV-2, and its ability to address the emerging public health epidemic. Many factors may cause differences between current expectations and actual results including unexpected safety or efficacy data observed during preclinical or clinical studies, challenges in neutralizing SARS-CoV-2, difficulty in collaborating with other companies or government agencies, and challenges in accessing manufacturing capacity within China. Other factors that may cause actual results to differ from those expressed or implied in the forward-looking statements in this press release are discussed in Virs filings with the U.S. Securities and Exchange Commission, including the section titled Risk Factors contained therein. Except as required by law, Vir assumes no obligation to update any forward-looking statements contained herein to reflect any change in expectations, even as new information becomes available.

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Contact:Vir Biotechnology, Inc.

InvestorsNeera Ravindran, MDHead of Investor Relations & Strategic Communicationsnravindran@vir.bio+1-415-506-5256

MediaLindy DevereuxScient PRlindy@scientpr.com+1-646-515-5730

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Vir Biotechnology Identifies Two Antibodies That Bind to the Spike Protein of 2019-nCoV, Newly Named as SARS-CoV-2 - Yahoo Finance

Immunology

E.A.T Announces Winners of $1 Million Grand Challenge to End Anaphylaxis – Yahoo Finance

New microbiome treatments and targets win Challenge as decided by distinguished panel of scientists, investors and entrepreneurs.

Winners to be awarded on February 27 at an event hosted by Bank of America Private Bank in New York City.

FAIRFIELD, Conn., Feb. 12, 2020 /PRNewswire/ --End Allergies Together (E.A.T), a non-profit organization that funds research for the growing food allergy epidemic affecting approximately 32 million Americans, will award an initial $1 Million investment between two efforts. The first is a joint project between Vedanta Biosciences, Inc., led by Rose Szabady PhD, and Massachusetts General Hospital, led by Wayne Shreffler MD, PhD. It will evaluate the immune mechanisms involved in and the effectiveness of VE416, a first-of-its-kind microbiota therapeutic to restore immune balance in the food allergic intestine. The second effort, led by Talal Chatila MD, PhD from Boston Children's Hospital, will look at the protective effect of targeting a new pathway to stop anaphylaxis. Both efforts have significant potential for targeted therapies offering long-term protection against food-induced anaphylaxis while simultaneously promoting oral immune tolerance. The awards event hosted by Bank of America Private Bank will take place on Thursday, February 27 in New York City.

End Allergies Together (E.A.T), a non-profit organization that funds research for the growing food allergy epidemic affecting approximately 32 million Americans, announces winners of $1 million Grand Challenge to end anaphylaxis. The awards event hosted by Bank of America Private Bank will take place on Thursday, February 27 in New York City.

What is anaphylaxis?

Anaphylaxis is a severe, potentially life-threatening allergic reaction. Various parts of the body can be affected, and symptoms such as throat tightening or closure, trouble breathing, swollen mouth, hives, dizziness and vomiting can occur within minutes or up to two hours after coming into contact with the allergen. Up to 20 percent of patients have a second wave of symptoms, called biphasic anaphylaxis, hours or even days after their initial symptoms have subsided.

The most common anaphylactic reactions are to foods, but individuals can also react to insect stings, medication and latex. With the rates of food allergy affliction now at 1 in 10 people in the U.S. and over 250 million worldwide, the rate of anaphylaxis is increasing. Further, according to the Journal of Allergy and Clinical Immunology, 39 percent of people with anaphylaxis may have had idiopathic anaphylaxis, a reaction that can not be explained by a known trigger.

"Anaphylaxis represents one of the most urgent of medical emergencies, in which rapid diagnosis and prompt and appropriate treatment can mean the difference between life and death Although there has been steady progress in our understanding especially in the context of mouse models of the disorder the basic clinical management of anaphylaxis has changed little in decades." Journal of Allergy and Clinical Immunology

The impact of anaphylaxis on the individual and their family can be significant. "The first time I saw my child have an anaphylactic reaction, I was changed forever," said Hillary Tolle Carter, Food Allergy Mother and Advocate. "You can no longer accept that food allergies are no big deal. It affects every aspect of your life. Every time food is involved you have to plan ahead, ask questions and be prepared with safe options for your child. The constant fear of that next anaphylactic reaction can take a serious toll on the entire family."

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E.A.T launched the Anaphylaxis Challenge in the spring of 2019 and brings together communities invested in preventing or ending life-threatening anaphylaxis. TheChallenge will accelerate progress by encouraging cooperation among those working within food allergy and across disease states to seek new and better solutions to take the life-threatening fear out of allergic reactions.

Dozens of researchers from private companies and public institutions entered The Challenge by submitting research business plans with potential solutions to help detect, prevent and/or better treat anaphylaxis (other than administering epinephrine). The award money will serve as seed funding to help accelerate andadvance the research and development required to bring these promising treatments closer to commercial viability.

Winner: Massachusetts General Hospital and Vedanta Biosciences, Inc.

"We are grateful for this recognition from E.A.T as we continuetoadvance our microbiome-derived product candidate for the potential treatment of food allergies in collaboration with Dr. Shreffler," said Rose Szabady Ph.D., Associate Director of Immunology, Vedanta Biosciences. "Mounting scientific evidence suggests that the microbiome plays an important role in food allergies, and this award recognizes the importance of further understanding the effects of the microbiota on the human immune system," continued Szabady. "We believe this work willshed light on the mechanisms by which our interventions modulate allergic immune response, and in turn, support continued development of our product candidate for patients seeking options other than avoidance."

Winner: Boston Children's Hospital

"We are most honored that our project was chosen by E.A.T's Panel. By targeting an immune mechanism central to the pathogenesis of food allergy and anaphylaxis, we aim not only to prevent this life-threatening complication but also to restore the immune system's tolerance to the allergenic foods," said Talal Chatila MD, PhD from Boston Children's Hospital. "We anticipate our studies will help bring forth a novel set of therapeutics for the treatment of food allergy-related anaphylaxis to the benefit of the patients and their families."

Honorable Mentions

The Challenge is a multi-year, multi-investment process whereby E.A.T, in collaboration with its Panelists, will provide funds, guidance and hands-on support to the most promising efforts. These include both the immediate awarding of $1 Million to the Winners as well as a commitment to partner with and consider future funding for a select group of Honorable Mentions which includes:

Dr. Joon Yun, M.D., an E.A.T Challenge Panelist and president of Palo Alto Investors explains the benefit of the Challenge model: "Grand Challenges can help nurture innovations in areas of unmet needs. The excitement and momentum associated with Grand Challenge competitions can help attract more attention, people, ideas, and funding to the issues of life-threatening anaphylaxis and food allergies."

Other distinguished Challenge Panelists include:

"I am extremely grateful to our Panelists who committed immense time, thought, analysis and heart to this process over the past six months," said Elise Bates, President and Cofounder of E.A.T. "With their guidance and expertise, we have an exciting outcome for this first phase of our Challenge. Both winners have a clear path ahead based on positive results from initial animal and human studies."

Kindly hosted by Bank of America Private Bank on Thursday, February 27, the awards event will feature the winners and their work as well as a discussion about investing in food allergies with E.A.T Panelists Dr. Eric Edwards and Dr. Joon Yun as well as a representative from Bank of America.

To inquire about this event, please email Tania@endallergiestogether.org

About End Allergies Together (E.A.T)

E.A.T is a 501(c)(3) non-profit organization focused solely on raising money for food allergy research. E.A.T was cofounded in 2015 by Elise and Greg Bates and Kim and Tom Hall, who have children with severe food allergies, to help bridge the significant gap in research funding for this growing epidemic now affecting nearly 1 in 10 Americans and 250 million people globally. Since inception, E.A.T has committed to eleven promising research efforts across thirteen leading institutions.

Press Contacts: Kriskey + Lane Communications Susan Kriskey, susan@kriskeylane.com Marni Lane, marni@kriskeylane.com

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Immunology

Allergy & Asthma Center Celebrates 25th Anniversary with the Launch of New Website – P&T Community

ROCKVILLE, Md., Feb. 12, 2020 /PRNewswire/ --Allergy & Asthma Center, the largest specialty practice serving pediatric and adult patients across the DMV, today unveiled its redesigned website commemorating its 25 years of dedication to delivering state-of-the-art allergy and asthma care for patients in a new up-to-date, highly-engaging website.

The new launch of premierallergist.com comes at a critical time when a patients' experience with a medical practice's website is just as important as their experience with the care they receive. Allergy & Asthma Center understood this, which prompted them to make an array of changes, not only in where their site lives and how it functions, but how visitors interact with content and, most important, the safety of patient information.

The most noted changes include:

"Launching the new website alongside celebrating our 25 years in business has been a great way to start the year," said Dr. Prasad Nataraj, Medical Director for Allergy & Asthma Center. Prospective patients deserve the best of both worlds their experience with our practice online and when they walk through our doors. This patient-centric thinking is what we strive to improve so that we can thrive for another 25!"

The new website was developed by PracticeBeat's best-in-class patient access, acquisition, and retention platform. For more information visit http://www.practicebeat.com.

About Allergy & Asthma CenterAllergy & Asthma Center, one of the largest single allergy, asthma and clinical immunology practices in Maryland, Virginia, and Washington, D.C., was established by Prasad M. Nataraj, M.D. in 1995. Our experienced team of healthcare professionals offer treatment to both adults and children of all ages, and our 20 convenient locations span across Maryland and the DC Metro area. Both our staff and our specialists are passionate about adhering to core principles that make our practice exceptional, including: Patient-centered care, accessibility and availability, compassionate medical council, innovative medicine, attention to the underlying source of the problem, and patient empowerment and education. http://www.premierallergist.com

Media Contact:

Kathy Ruxton703.340.6343 234034@email4pr.com

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Immunology

Plasma Fractionation Market – 2020 Share, Size, Growth, Trends, Business Insights, Competitive Landscape, Opportunities, Segments, Key Players,…

According to Plasma Fractionation Market 2020 Global Industry Forecast to 2026 Report published by Fortune Business Insights, the Global Plasma Fractionation Market size to reach $9.5 billion at CAGR of 10% by 2026. Market for Plasma Fractionation segmented by Product Type (Instruments and Reagents & Consumables), Technique (Hematology, Immunohistochemistry, Molecular Diagnostics, Diagnostic Imaging, Clinical Biochemistry, and Others), Animal Type (Livestock and Companion), End-user (Veterinary Hospitals & Clinics, Veterinary Reference Laboratories, and Others) and Regional Forecast 2019-2026.

According to Plasma Fractionation Market 2020 Global Industry Forecast to 2026 Report published by Fortune Business Insights, the Global Plasma Fractionation Market size to reach $38.65 billion at CAGR of 6.2% by 2026. Market for Plasma Fractionation segmented by Product Type (Instruments and Reagents and Consumables), Technique (Hematology, Immunohistochemistry, Molecular Diagnostics, Diagnostic Imaging, Clinical Biochemistry, and Others), Animal Type (Livestock and Companion), End-user (Veterinary Hospitals and Clinics, Veterinary Reference Laboratories, and Others) and Regional Forecast 2019-2026.

Plasma Fractionation Industry Key Players Analyzed in Report Are:

CSL, Octapharma, Grifols, S.A., Kedrion S.p.A., Biotest AG, Shire, Baxter, LFB.

Request a Sample Copy of the Research Report: https://www.fortunebusinessinsights.com/enquiry/request-sample-pdf/plasma-fractionation-market-101614

Global Plasma Fractionation Market Insights:

The Global Plasma Fractionation Market is expanding at notable growth rate; this market growth is attributed to factors such as Increasing Prevalence of Congenital Disorders and Rising Usage of Plasma Proteins.

Fortune Business Insights in a new report, titled Plasma Fractionation Market Size, Share and Industry Analysis, By Product Type (Albumin, Immunoglobulin (Intravenous Immunoglobulin and Subcutaneous Immunoglobulin), Coagulation Factors (Factor IX, Factor VIII, Prothrombin Complex Concentrates, Fibrinogen concentrates and Others), Protease Inhibitors and Others), By Application (Immunology and Neurology, Hematology, Critical Care, Pulmonology and Others), By End User (Hospitals and Clinics, Clinical Research Laboratories and Others (Academic Institutes, etc.)) and Geography Forecast, 2019-2026 states that the market was worth USD 24.07 Billion in the year 2018 and is likely to reach USD 38.65 Billion by 2026.

The process of separating several plasma components is called plasma fractionation. These components are separated with the help of processes such as ethanol fractionation and cryoprecipitation. Rising prevalence of congenital disorders is driving the global plasma fractionation market. Unlike pharmaceutical and biopharmaceutical industry, plasma fractionation industry uses human blood plasma or living cells as raw materials to manufacture critical drugs. These life-saver products help in the treatment of severe health conditions caused by congenital metabolic deficiencies, immunological disorders, and trauma. This, along with increasing FDA approvals, will create lucrative growth opportunities for the market.

Plasma Fractionation Market Segmentation:

Plasma Fractionation Market Size, Share and Industry Analysis, By Product Type (Albumin, Immunoglobulin (Intravenous Immunoglobulin and Subcutaneous Immunoglobulin), Coagulation Factors, Protease Inhibitors and Others), By Application (Immunology and Neurology, Hematology, Critical Care, Pulmonology and Others), By End User (Hospitals and Clinics,), and Geography Forecast 2019-2026

Regional Insights:

Report analyzes Global Market for Plasma Fractionation by North America, South America, Asia-Pacific, Europe, Middle East and Africa.

Among regions, North America is anticipated to maintain its dominance in the global plasma fractionation market in the forecast years. As per the research report, the market was valued at USD 10.08 Billion in 2018. The market in this region is expanding with the rising support from government regarding new plasma facilities. Increasing research activities on plasma fractionation processes with well-established healthcare infrastructure majorly contributes to the growth of the market in this region.

Following North America, Europe is the second-most leading region in the market owing to the rising sales of plasma proteins. In addition to this, the increasing prevalence of plasma indications and advanced improvements in the plasma fractionation process are encouraging growth in the market in this region. The market in Asia Pacific is prophesized to rise at a higher CAGR owing to the rising adoption of blood plasma fractionation in countries such as India and China.

Plasma Fractionation Market Growth Factors:

As per the data published by the National Institutes of Health, every year around 40,000 kgs of intravenous immunoglobulin and approximately 5,00,000 kgs of human albumin is produced all across the globe. This shows that the usage of immunoglobulin is increasing at a rapid rate, which is one of the primary factors responsible for driving the market. These immunoglobulins act as antibodies. Moreover, the adoption of immunoglobulins is increasing as play a crucial role in the detection and destruction of viruses and bacteria. They have been tested for the RandD of autoimmune disorders or Alzheimers. The demand for IgG products is fueling across several regions, which in turn, is increasing the sales of these products. All the above mentioned factors are anticipated to contribute to the growth of the market in the

Highlights of the Report:

In-depth analysis of various insights, namely, Plasma Fractionation Market trends, growth drivers, opportunities, and other related challenges.

Comprehensive details of key market players, their core competencies, and Plasma Fractionation Market share.

The potency of suppliers and buyers to make better business decisions.

Lists out the market size in terms of volume.

Table of Content:

1.1. Research Scope

1.2. Market Segmentation

1.3. Research Methodology

1.4. Definitions and Assumptions

3.Market Dynamics

3.1. Market Drivers

3.2. Market Restraints

3.3. Market Opportunities

4.1. Number of Cataract Surgeries - For Key Country/Region

4.2. Pipeline Analysis

4.3. Key Industry Developments - Mergers, Acquisitions, and Partnerships

4.4. Technological Advancements in Ophthalmic Surgery

4.5. Introduction of New Products / Approvals (by Major Players)

Continued

About us:

Fortune Business Insights offers expert corporate analysis and accurate data, helping organizations of all sizes make timely decisions. We tailor innovative solutions for our clients, assisting them address challenges distinct to their businesses. Our goal is to empower our clients with holistic market intelligence, giving a granular overview of the market they are operating in.

At Fortune Business Insights we aim at highlighting the most lucrative growth opportunities for our clients. We therefore offer recommendations, making it easier for them to navigate through technological and market-related changes. Our consulting services are designed to help organizations identify hidden opportunities and understand prevailing competitive challenges.

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