Cell Biology

Commission announces winners of its first coronavirus research call – Science Business

Two of 17 projects selected by the European Commission in its first research call to tackle COVID-19 are developing vaccines against the disease.

The two vaccine projects are led by researchers at Karolinska Institutet, Swedens top medical university and AdaptVac, a Danish biotech start-up.

Karolinska researchers Matti Sllberg and Gustaf Ahln plan to start testing their vaccine candidate in animal models within a couple of weeks and hope to be able to begin the first trials in COVID-19 patients in 2021 at the Karolinska University Hospital.

With the EU grant, the project, called Opencorona, now has a large part of the money needed to come up with a vaccine candidate and see it through a phase I clinical study. It is a relief to know that we are now financed all the way to studies in humans, said Sllberg.

For the second vaccine project, Prevent-nCoV, AdaptVac has been awarded a 2.7 million grant to apply its synthetic virus-like particle technology. In common with a number of companies that are now turning their hands to developing COVID-19 vaccines, AdaptVac has previously been applying the technology to cancer vaccines. It aims to complete safety and efficacy testing of a COVID-19 vaccine within 12 months.

We strongly believe that this technology will be a key player in global emergencies, such as the COVID 19 epidemic said AdaptVac CEO Wian de Jongh.

Three projects at Karolinska

In addition to the vaccine project, Karolinska researchers have won two other grants from the EUs pop-up call, totalling 9 million for the university. The funds are to be split equally between the three teams and will cover a period of two years.

Researchers Qiang Pan Hammarstrm, Harold Marcotte and Lennart Hammarstrm will lead a project on a passive immunotherapy against the new coronavirus, based on antibodies found in blood of recovered COVID-19 patients.

We believe that antibodies represent a weapon of choice to treat the disease and prevent continued spread of the virus globally, Pan Hammarstrm said.

At Karolinksas department of microbiology, tumour and cell biology, Benjamin Murrell, Gerald McInerney and Gunilla Karlsson Hedestam will work on the development of antibodies that could block the virus from infecting cells.

The researchers have started working on animal models and hope to identify antibody candidates that could be used for treating COVID-19 patients. Access to an arsenal of efficient anti-viral antibodies will be important to help control the spread of [COVID-19], Murrell said.

Pandemic modelling

The second largest consortium announced by the commission, Exscalate4CoV, led by the Italian pharmaceutical company Dompe farmaceutici SpA, will resolve the 3D structures of essential viral proteins, which will then be used to generate computer models of likely future mutations of the virus, and as the basis for in silico screening of compound libraries (either from repurposing libraries or from proprietary or commercial compound libraries).

The researchers will use the Exscalate supercomputing platform, which can process three million molecules every second and has a database of 500 billion molecules.

The protein structure lab of a former European Research Council grantee, Marcin Nowotny is one of the 17 partners in Exscalate4CoV. Nowotny and his team in Warsaw will work on the crystal structure of functional proteins in the novel coronavirus and compare them to other viral proteins. Drug development is very tricky, but if we are lucky, we may be able to find a substance which can be repurposed, which we know is safe in humans, and test it in patients, Nowotny said.

Epidemiology

A team of researchers at the University of Antwerp have won an award for the Recover project in which they will work on a survey to understand the impact of COVID-19 on EU citizens, a study on household transmission of the disease and a study how children contribute to the spread of the virus. The aim is to draw up recommendations for the EU on ensuring the safety of health workers during the epidemic.

In Sweden, the Hanken School of Economics has brought together 11 partners from six countries to work on Heros, a project that aims to improve the response to the virus outbreak. The researchers will use the 2.8 million grant to come up with better guidelines for crisis governance and public health emergencies.

A total of 89 partners from across Europe are involved in the projects announced by the commission. The full list is available here.

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Commission announces winners of its first coronavirus research call - Science Business

Cell Biology

Organ-Chips provide human-relevant insights into diseases and toxicity mechanisms – The Medical News

Organs-on-Chips technology has entered the mainstream and has reached 150 installations for use by researchers across many industries, including 10 of the top 25 biopharmaceutical companies, as well as leading international academic research centers and U.S. government laboratories, including the U.S. FDA through a collaborative agreement and the U.S. Army.

Organ-Chips that are currently available for use in the lab-ready platform developed by Emulate, Inc., include the Liver-Chip, Kidney-Chip, and new Intestine-Chip, launched commercially earlier this year. Ongoing R&D is supporting the development of additional Organ-Chips, such as the Brain-Chip, and new applications in key areas of biology and diseases, including applications in neurodegenerative disease, gastrointestinal diseases, and infectious diseases, such as COVID-19.

Combining biology and microengineering, Organ-Chips contain tiny hollow channels lined with tens of thousands of living human cells and tissues and can be used to predict human response. For early adopters conducting R&D related to drug discovery and development, the Organ-Chip platform provides human-relevant insights and answers to the complex questions required for disease modeling, target validation, and safety assessment in drug development.

Researchers can culture the chips--including the Liver-Chip, Kidney-Chip, and Intestine-Chip--using Emulate's portfolio of protocols, enabling research to understand how the human body responds to disease, medicines, chemicals, and foods. The lab-ready platform - including the Zo Culture Module, Organ-Chips, and application tools - recreates key factors of the body's dynamic cellular microenvironment, including tissue-to-tissue interfaces, fluid flow, and mechanical forces.

The lab-ready platform enables researchers with no prior experience with Organs-on-Chips to conduct studies, using the platform's supporting protocols and software to collect, analyze, and share data. This platform integrates into the workflows of researchers developing new drugs and products, providing human-relevant mechanistic data on toxicity and diseases that researchers can use to assess safety risks and make informed, efficient decisions throughout the drug discovery and development process.

We are excited to see researchers in industry, government, and academia use our Organs-on-Chips platform for a range of applications, including human-relevant disease modeling and studies to gain insights related to new drug modalities and disease mechanisms that are not feasible with conventional animal models or cell cultures. Organs-on-Chips technology provides a window into the inner workings of human biology and disease, and by putting the technology in the hands of researchers, we are changing the way medications and products are evaluated to help improve human health and bring new cures to patients."

Geraldine A. Hamilton, President and Chief Scientific Officer of Emulate, Inc

Emulate's platform is comprised of the following key components:

Emulate's lab-ready platform has its origins in a $37 million grant from the Defense Advanced Research Projects Agency (DARPA) in 2012 to the Wyss Institute for Biologically Inspired Engineering at Harvard University to create Organs-on-Chips to study complex human physiology outside the body. This foundational research enabled the development of chips with a level of human-relevant biological complexity not feasible with conventional cell-based systems, as well as instrumentation designed to enable any researcher to use the technology in their laboratories. Based on the success of this early research, Harvard established a worldwide license agreement to form the start-up company, Emulate, and the company became operational in January 2015. The Emulate team accelerated development of Organs-on-Chips technology to create the platform that is now commercially available, working with an extensive community of collaborators across industry, academia, and government agencies.

In addition to applications in drug discovery and development, Emulate's platform can be used in other industries, including cosmetics, food, chemical-based consumer products, and personalized health, to enable new understanding of human response to products.

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Organ-Chips provide human-relevant insights into diseases and toxicity mechanisms - The Medical News

Cell Biology

Study reveals major changes that occur in mammalian skin cells during wound healing – The Medical News

Reviewed by Emily Henderson, B.Sc.Mar 19 2020

A team of University of California, Irvine researchers have published the first comprehensive overview of the major changes that occur in mammalian skin cells as they prepare to heal wounds. Results from the study provide a blueprint for future investigation into pathological conditions associated with poor wound healing, such as in diabetic patients.

This study is the first comprehensive dissection of the major changes in cellular heterogeneity from a normal state to wound healing in skin."

Xing Dai, PhD, professor of biological chemistry and dermatology in the UCI School of Medicine, and senior author

This work also showcases the collaborative efforts between biologists, mathematician and physicists at UCI, with support from the National Institute of Arthritis & Musculoskeletal & Skin Diseases-funded UCI Skin Biology Resource-based Center and the NSF-Simons Center for Multiscale Cell Fate Research.

The study, titled, "Defining epidermal basal cell states during skin homeostasis and wound healing using single-cell transcriptomics," was published this week in Cell Reports.

"Our research uncovered at least four distinct transcriptional states in the epidermal basal layer as part of a 'hierarchical-lineage' model of the epidermal homeostasis, or stable state of the skin, clarifying a long-term debate in the skin stem cell field," said Dai.

Using single-cell RNA sequencing coupled with RNAScope and fluorescence lifetime imaging, the team identified three non-proliferative and one proliferative basal cell state in homeostatic skin that differ in metabolic preference and become spatially partitioned during wound re-epithelialization, which is the process by which the skin and mucous membranes replace superficial epithelial cells damaged or lost in a wound.

Epithelial tissue maintenance is driven by resident stem cells, the proliferation and differentiation dynamics of which need to be tailored to the tissue's homeostatic and regenerative needs. However, our understanding of tissue-specific cellular dynamics in vivo at single-cell and tissue scales is often very limited.

"Our study lays a foundation for future investigation into the adult epidermis, specifically how the skin is maintained and how it can robustly regenerate itself upon injury," said Dai.

Source:

Journal reference:

Haensel, D., et al. (2020) Defining Epidermal Basal Cell States during Skin Homeostasis and Wound Healing Using Single-Cell Transcriptomics. Cell Reports. doi.org/10.1016/j.celrep.2020.02.091.

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Study reveals major changes that occur in mammalian skin cells during wound healing - The Medical News

Cell Biology

Understanding the Brain in High-Definition: Rapid, Automatic Identification of Individual, Live Brain Cells – SciTechDaily

Nerve cells are shaped like young plants: big round seeds (cell bodies) surrounded by a nest of frizzy roots in one direction (dendrites) and a single long stem stretching out in the other direction (axon). This image shows variations in the location of some neuron cell bodies between different animals as ellipses. Each neuron is randomly colored. Neurons are arranged top-to-bottom and left-to-right in the graph as they are located nose-to-tail (anterior-posterior) and back-to-belly (dorsal-ventral) in a worm. Credit: Toyoshima et al., 2020, DOI: 10.1186/s12915-020-0745-2, CC BY-ND 4.0

Researchers working towards understanding the brain in high-definition, single-cell level of detail have designed a new computer program to identify each nerve cell in fluorescent microscope images of living worms. Previous attempts to automate the identification of individual nerve cells have been thwarted by the fact that the same cell can be in vastly different locations in different worms.

The worms areC. elegans, tiny roundworms common in soil and research labs around the world. Each of the 959 cells in the animals transparent, 1 millimeter-long bodies has been identified, named and mapped, including their 302 nerve cells.

Scientists completed the first map of theC. elegansnervous system in 1986 and have been improving it ever since. More recent projects include OpenWorm, an ongoing global effort to design a cell-by-cell and behaviorally accurate virtualC. elegans a research-worthy version of a Tamagotchi pet.

The central DNA-containing cell bodies of C. elegans neurons are shown with the three fluorescent colors used in the genetically modified strain of C. elegans developed by the research team. Note how neighboring cells are different colors. Successfully annotated neurons are labeled with letters and cells whose identity could not be annotated are labeled with numbers. Not all 302 C. elegans neurons are present in this image. Credit: Toyoshima et al., 2020, DOI: 10.1186/s12915-020-0745-2, CC BY-ND 4.0

Despite their value, generalized brain atlases, so-called connectome maps, are still no help for identifying neurons in individual, live, wriggling worms.

Imagine if you knew the names of all the cities on a map, but the cities moved each time you looked. That is what its like, trying to compare current brain atlases to living organisms, said Professor Yuichi Iino from the University of Tokyo, co-last author of the recent research paper published in BMC Biology.

Iinos research group wants to identify and map each nerve cell in livingC. elegansso that they can chart the pathways of electrical impulses that make behaviors, learning and memory possible.

C. elegans brain neurons are not trapped in a skull, but just form a loosely packed group of 150 neurons in the head region of the animal.

The neurons are tiny, and in the head ofC. elegans they are surrounding this large bulb thats part of the digestive system, so they get pushed and pulled around a lot as the animal moves or eats, explained Iino.

Researchers began by finding unique combinations of genes that, when artificially attached to fluorescent protein tags, would cause 35 different small groups of neurons to glow under a microscope.

These new genetically modified strains ofC. elegansmade all of the researchers subsequent image studies and computer programming work possible.

Researchers identified individual neurons in 311 worms in total, about 10 worms for each of the 35 neuron groups, and measured the distances and relative positions between pairs of neurons in the microscopy images.

Although neurons were known to shift within each worm, no one expected the neurons to have different home base locations in different individuals. The positions of the central cell body of some neurons can vary by more than 0.02 millimeter between different animals, a significant distance for an animal only 1-millimeter long.

IndividualC. elegansare thought to be uniform because they all have almost the same cell lineages and a stereotyped neural circuit. It was really surprising, though, how large the positional differences are between individual animals, said Assistant Professor Yu Toyoshima, a co-first author of the recent research paper and member of the Iino lab.

The research team then used their new position variation data and theC. elegansconnectome brain atlas to develop a computer program to automatically identify neurons. The program uses a mathematical algorithm to analyze a microscopy image of theC. elegansbrain and assign the statistically most likely identity to each neuron based on that neurons position in relation to other neurons.

The algorithm is only 60 percent accurate, which is too low for fully automatic cell identification, but it speeds up our work enough to make other projects possible to understand neural networks based on whole-brain imaging data, said Toyoshima.

Part of what made this project possible inC. elegansis that every neuron was already known and named. Using a similar technique in other animals would require fine-tuned genetic manipulation to cause groups of neurons to glow under a microscope and knowing how many neurons need to be identified.

The human brain has billions of neurons, so understanding our own brains at the single-cell level would be extremely difficult.C. eleganshave small brains, but they can still learn and change behaviors, so they could allow us to understand how networks of neurons create behavior, said Iino.

Reference: Neuron ID dataset facilitates neuronal annotation for whole-brain activity imaging ofC. elegans by Yu Toyoshima, Stephen Wu, Manami Kanamori, Hirofumi Sato, Moon Sun Jang, Suzu Oe, Yuko Murakami, Takayuki Teramoto, Chanhyun Park, Yuishi Iwasaki, Takeshi Ishihara, Ryo Yoshida and Yuichi Iino, 19 March 2020, BMC Biology.DOI: 10.1186/s12915-020-0745-2

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Understanding the Brain in High-Definition: Rapid, Automatic Identification of Individual, Live Brain Cells - SciTechDaily

Neuroscience

IMMERSION NEUROSCIENCE INDEX REVEALS THE PUBLIC CRAVES DIRECTION FROM ITS ELECTED LEADERS, NOT CELEBRITIES, DURING A CRISIS – Multichannel News

LOS ANGELES Immersion Neuroscience, the worlds most advanced predictive software company unlocking neuroscience to measure what people love, announced today a new Immersion Index revealing people's reaction to celebrities vs. elected officials communications about the current COVID-19 pandemic.

Immersion researched the most effective way to share information with the public about coronavirus. This new study compares celebrities and their social media messages with elected officials.

The best way to determine if communication is effective is to measure how well it "sticks" in the brain. Science has established that when the brain is immersed in information, it is remembered, shared with others, and acted on. Highly immersive information is what will reduce the spread of the coronavirus and save lives, said Dr. Paul J. Zak, Founder of Immersion.

The research study: Immersion asked participants to turn on their Apple watches or other wearable sensors and emailed them six videos to view online. The videos ran for one-and-a-half to two minutes and featured President Trump; Vice President Pence, who leads the White House Coronavirus Task Force; Dr. Anthony Fauci, who leads the National Institute of Allergy and Infectious Diseases and is a member of the Coronavirus Task Force; Georgia Governor Brian Kemp; singer Cardi B; and actor and former governor of California Arnold Schwarzenegger, all speaking about the coronavirus outbreak.

The study revealed that communication about coronavirus by government leaders is significantly more effective than a celebrity rant or an offbeat video with miniature horses, for example.

The Immersion platform aggregated neurologic responses and returned an average Immersion value from 1-10 for each video.

Immersion Index results for communication effectiveness are:

Vice President Pence generated neurologic immersion that was 48% higher than the next most immersive speakers, a tie between President Trump and Governor Kemp. Dr. Fauci was a close third at 53% less immersive, while Arnold and Cardi B were at the bottom of the list at 61% and 64% less immersive than Mr. Pence.

The results show that fact-based videos from elected officials, delivered without theatrics were significantly more immersive, meaning these are more likely to motivate actions by citizens.

We salute celebrities for reminding the public to be safe. But, when times are tough, this study shows that brains know that experts provide the most valuable information. If you ask people which videos they "like" or find "entertaining," they will choose the stars over the experts. Extensive research has shown that "liking" has no relationship to what people do. In this time of crisis, action is what matters. That is why measuring neurologic immersion is so important, said Immersion CEO Scott Brown.

Fifteen years of peer-reviewed research has proven that when the brain produces a specific set of unconscious responses called "immersion," it identifies an experience as valuable.

Immersions proprietary solution and software is the world's most accurate way to measure the brain's unconscious emotional responses to virtually any type of content whether its video, music, live events, training, educational resources and more. Developed by distinguished research scientists, Immersions simple to use and scalable predictive SaaS platform democratizes neuroscience so that anyone can measure what people love at scale.

The Immersion platform is unique in its ability to perform distributed neuroscience which becomes essential at a time when the world is sheltering in place. Immersion measures brain responses any place that people are using a mobile app that sends data to cloud servers. Algorithms developed by Immersion scientists infer brain activity from a small wearable sensor.

To learn more about Immersion, visit http://www.getimmersion.com.

For more information, contact:

Andrew Laszacs

Bob Gold & Associates

310-320-2010

immersion@bobgoldpr.com

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IMMERSION NEUROSCIENCE INDEX REVEALS THE PUBLIC CRAVES DIRECTION FROM ITS ELECTED LEADERS, NOT CELEBRITIES, DURING A CRISIS - Multichannel News

Neuroscience

HeyHuman’s Neil Davidson: how neuroscience can find new ways to tell ad stories – More About Advertising | Insights into Advertising

Weve been telling stories since advertisings embryonic flutters, baby steps and terrible teens as such, some of the industrys most memorable moments have been narrative-heavy.

And traditional storytelling still demands attention. No matter what you think of them, those John Lewis Christmas ads get people talking every year, and there is a reason for that. Even as storytelling is increasingly informed and enabled by technology and data; as were bombarded with so much more stuff on a daily basis, our brains are still partial to an old-fashioned tall tale.

And it can be proven with neuroscience.

Neuroscience testing tells us that people are 22 times more likely to remember information when its woven into a story. More recently, research has shown how stories can stimulate neural coupling, which basically means a link is created between storyteller and listener. As the advertising space becomes more cluttered with the aforementioned stuff, that link between brand and customer is vital.

And as the choice of platforms available to us grows, the concept of a story is becoming ever more fluid. A story is an arc, and that doesnt necessarily have to be carried out via traditional methods experiential and social are both prime examples.

But first, lets look at more traditional storytelling spots like John Lewis Excitable Edgar or Apples The Surprise; both are cracking displays of narrative, with the product and brand taking a few steps back. Instead, its the loveable characters, heartwarming stories and lengthy run times leading the way, melding the art of advertising with short film. These are powerful stories and they evoke powerful reactions.

But you dont need to create a five-minute mini-epic to connect with consumers. If you can condense your narrative down, you stand a better chance of capturing peoples ever-shortening attention spans. For example, YouTubes pre-roll ads are a real creative challenge for advertisers with just six seconds to promote products (possibly even less time than that, when scrolling is taken into account.) Brands have to be more efficient than ever to convey messages.

And yes, although theres only really seven basic plots, there are more than seven ways to memorably execute said plots. The current advertising landscape is well placed for experimentation, and if you can begin to toy with the storytelling format, then you stand a better chance than most. Pushing the boat out can be scary, but theres a way to anchor it. And its calleddrumrollneuroscience.

Last year, we worked with Guinness Africa on its Flavour Rooms project. The brief was simple enough: engage Africans aged between 18 to 34-years-old, with the brand through a physical experience. Why? The legacy Guinness story wasnt resonating with that younger demographic. Naturally, we used neuroscience to conduct research on our target audience, and discovered words like bold, rich, refreshing and bittersweet to be the most motivating.

That all fed into our multi-sensory Flavour Rooms activation, which comprised a room dedicated to each of those Guinness characteristics. These ranged from an eye-popping room celebrating the boldness of African culture to a room adorned with lavish, silky textures all of which enhanced different aspects of the famous Guinness flavour.

It was a new way to tell an old story. It was what I like to call unusual everyday: using unconventional methods to frame an established drink in a completely different light. It completely switched up the narrative.

Its always good to have a story that you think your consumers will engage with, sure. But its better to have one that you know they will. In a world where campaigns potentially live or die based on their narrative, why wouldnt you want to know what consumers are thinking before you embark on yours?

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HeyHuman's Neil Davidson: how neuroscience can find new ways to tell ad stories - More About Advertising | Insights into Advertising

Neuroscience

Global Neuroscience Market 2025| By Top Key Players Alpha Omega, Axion Biosystems, Blackrock Microsystems LLC, Femtonics Ltd., Intan Technologies and…

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Global Neuroscience Market 2025| By Top Key Players Alpha Omega, Axion Biosystems, Blackrock Microsystems LLC, Femtonics Ltd., Intan Technologies and...

Neuroscience

A Community That Writes Together – Duke Today

Write!

For Sarah Gaither, this command reminds her what she needs to make time to do. As an assistant professor of psychology & neuroscience at Duke, she balances a robust teaching and research load with administrative duties, meetings with collaborators and students, leadership of the Duke Identity & Diversity Lab and more. Advancing her own scholarship can get squeezed to the margins, but she cant allow that to happen during this critical period in her career.

From manuscripts, grants and book chapters to opinion pieces and responses to editors, junior faculty need to write to build their tenure files and advance in rank.

Protected writing time is key. And for Black scholars like Gaither, a supportive community can be a big help in navigating this stage of faculty life.

Seed Funding for Faculty Initiatives

Dukes Office of the Vice Provost for Faculty Advancement has provided seed funding for WRAP since 2018. Faculty Advancement Seed Grants provide a financial head start for faculty-led initiatives aiming to foster a sense of community, build networks and promote a welcoming and respectful climate for all members of Dukes academic units.

The seed grants program is part of the offices multifaceted approach to faculty development and advancement, whose goals are to support hiring and retention, to provide resources and programs to help faculty succeed as scholars and mentors and to foster a welcoming and professional environment.

When faculty mobilize around campus, that influences the whole ecosystem here, says Sherilynn Black, associate vice provost for faculty advancement. Everyone can benefit, including postdocs, students and staff.

A member of the Duke community for the past two decades, Black earned her Ph.D. in neurobiology, followed by a postdoc position and an appointment as assistant professor of the practice of medical education.

Being with the group is like exhaling, says Black, who is an active participant in WRAP herself. Its implicitly understood what youre going through.

WRAPs seed grant covers food at campus-based meetings along with lodging, meals and travel related to the writing retreats.

Gaither joined the Writing and ReseArch Productivity (WRAP) Group for Underrepresented Faculty shortly after coming to Duke. Today she serves as co-leader along with Tyson Brown, associate professor of sociology, who founded the group in 2016. WRAP offers weekly writing sessions, weekend writing retreats and other programming. The aim is to build community among Black faculty, increase their publication rates and enhance their sense of inclusion on campus

With very few minority faculty in my department, WRAP has been essential in creating a support system for my faculty life transition, Gaither says, and the guided writing time has been critical during my first years on the tenure track.

As universities pursue efforts to improve the racial climate on their campuses, Brown says that faculty of color often do a disproportionate share of racial equity labor such as serving on diversity committees, helping to navigate racial incidents and recruiting and training students of color. While racial equity labor is essential, it can also be taxing and take away from time for research.

WRAP members participate in a weekly two-hour writing session. In the first 10 to 15 minutes, we talk about our goals for that session, Gaither says. We go around the table and hear from each person. Then we do 90 minutes of writing. We close by taking 15 minutes and asking each person to assess the success of that session as well as how things are going with research, teaching and life in general.

If faculty are not on campus, they can join the group virtually.

Each week an average of seven members show up and a total of 22 faculty and postdocs have participated. They represent 14 disciplines and units across campus.

Its like a triple accountability system, Gaither says. Youve got the time blocked, and people mark their calendars. And when were writing with similar people, we want to see how things are going; if someone doesnt show, Ill call them and ask where they were. Theres also a shared Google sheet. Everyone logs the hours and minutes they spend every week on writing.

In addition to the weekly sessions, two weekend-long writing retreats are offered during the year to increase the groups writing time. Each person aims to create a publication-ready article by engaging in structured writing sessions.

As the group evolves, Brown and Gaither are adding some new components. They see a need for making connections between faculty ranks and plan to encourage Black associate professors and visiting faculty to join. Senior faculty members and campus leaders will also bridge the gap by serving as guest speakers.

A one-day writing retreat in Durham will supplement the weekend retreats and accommodate faculty for whom overnight travel is a challenge.

WRAP members help each other by reviewing drafts and discussing strategies for navigating job situations. A listserv with 30 members supplements in-person conversations.

Co-leading and participating in WRAP programmatic activities has greatly enhanced my productivity, and led to opportunities and connections with faculty in other units across the university, Brown says. Ive found that meeting weekly to write alongside others has been useful for providing accountability and protected time for writing. Participating in the group has also fostered a sense of community and provided opportunities for us to discuss our scholarship, teaching and unique experiences.

Other members report improved daily writing habits, greater self-confidence both academically and personally, increases in research productivity and enhanced feelings of inclusion and community.

At last count, Brown and Gaither identified a substantial output among members over the past two years: collectively they submitted 28 papers, 17 grant proposals and 14 conference abstracts, and they have two books in preparation.

Perhaps most importantly, they are doing this work together as a community. The group has been so supportive, says Gaither. It has made my Duke experience better!

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A Community That Writes Together - Duke Today

Anatomy

Anatomy Chart – How to Make Medical Drawings and Illustrations

What is an Anatomy Chart?

An anatomy chart refers to a visual depiction of the human body.

It can show the entire body or focus on a particular system using systemic anatomy such as the muscular, skeletal, circulatory, digestive, endocrine, nervous, respiratory, urinary, reproductive, and other systems.

There are many different branches of anatomy dealing with the human body: surface anatomy, gross anatomy, embryology, histology, radiographic, pathologic, and more.

Gross anatomy deals with large, visible body parts. Surface anatomy is a subset of gross anatomy that deals with only external features of the body. Embryology deals with the development of anatomical systems prior to birth. Radiographic anatomy studies the parts of the human body made visible using a variety of radiation techniques such as X-rays or MRIs. Pathologic anatomy focuses on how diseases affect and change the human body. Histology studies microscopic anatomy such as tissues and cells visible only under a microscope.

Anatomy charts serve two main purposes: education in the form of anatomy worksheets and presentation in the form of simple healthcare illustrations. Anatomy illustrations are pre-made illustrations with descriptions of a particular part, or system of the body. Anatomy worksheets are an illustration of a certain part or system of the body, with 'fill in the blank' spaces pointing to different sections of the illustration. Anatomy charts can be specific to one part of the body, such as a knee joint, or cover a combination of body parts: the skeletal system, for example.

Anatomy charts are used mostly for educational purposes for students of all ages. An anatomy illustration would likely be used for study guides, whereas an anatomy worksheet might be used as test material. These illustrations can also be used by doctors to educate patients. Doctors often use them to explain different conditions.

Anatomy illustrations are sometimes used by X-ray technicians to determine what bones need to be visible in an X-ray and what specific bone is fractured. If an X-ray technician is conducting an MRI they can also use these illustrations to determine what muscle or tissue is torn.

Have you ever been in a treatment room at your doctor's office and seen a picture of a heart or a digestive system? These will commonly isolate or direct your attention to a specific artery or provide the names of different organs. These are great examples of anatomy illustrations.

SmartDraw offers one of the largest selections of excellent pre-made anatomy worksheets and illustrations for you to use. You may modify any of these for your specific need. They are a useful resource for:

If you were a professional designer, you could use a tool like Adobe Illustrator to draw detailed illustrations of various anatomical systems. Even if you were good, it would probably take hours. SmartDraw has anatomy chart templates that you can just drag and drop to a page so you don't have to be a professional designer or waste a lot of time redrawing something that has a standard look.

You can easily customize the included anatomy chart templates with colors and labels as you see fit.

The best way to understand anatomy charts is to look at some examples of anatomy charts.

Click on any of these anatomy charts included in SmartDraw and edit them:

Browse SmartDraw's entire collection of anatomy chart examples and templates

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Anatomy Chart - How to Make Medical Drawings and Illustrations

Anatomy

A.D.A.M. Interactive Anatomy Online. – A.D.A.M. Education

The most comprehensive, interactive anatomy resource for teaching and student practice is now available via online subscriptions in two different editions with more options than ever before:

View Online Demo

Both editions includes a new design and online functionality that improves performance and makes it easier than ever for users to explore and learn.

The most comprehensive digital database of detailed anatomical images in the world, with the ability to identify over 20,000 anatomical structures from different body orientations (anterior, lateral, medial, posterior, lateral arm, medial arm). Structures can be identified through a secondary language; English (undergraduate), French, German, Hungarian, Italian, Japanese (Kanji), Japanese (Yomi), Portuguese, Spanish, Swedish.

Includes meticulously detailed full-color illustrations of body parts, organs, structures and systems complete with pinned structures for student identification.

Features more than 3,000 illustrations for teaching and learning in a clinical context.

Features 28 professionally-produced animations covering topics related to physiology, disease and surgery.

Curriculum Builder is a great way to integrate your text with customized images from AIA for dynamic live lectures or for student lab activities. With our recent release, AIA now includes pre-built curriculum for 11 different body systems you can assign or use as a start for your own curriculum.

A.D.A.M. Interactive Anatomy online as it has always been offered, includes 3D Anatomy and the illustrated Multimedia Encyclopedia. If using AIA for lecture or presentation is more important to you then this is the edition for you.

Includes a library of 3D models that users can interact with hundreds of detailed structures where the view and orientation automatically adjusts to highlight structures in the highest possible resolution. Models include: Heart, Ear, Eye, Skull, Brain, Female and Male Reproductive System, Lungs.

Includes one of the worlds most comprehensive libraries, complete with a full repository of illustrations, diagrams, photos and videos. The medical encyclopedia includes 3,600 articles covering diseases, conditions, procedures, treatments, surgeries and more.

A.D.A.M. Interactive Anatomy Lite has been added as a new edition to provide more student practice and assessment at a more affordable price. This edition of AIA is most appropriate for cost-conscious customers who want students to have access to more student practice.

This interactive assessment tool has been enhanced and included 952 key anatomical structures in 11 body systems. It includes traditional drag-and-drop identification questions, as well as complete the statement formats. A performance summary report can be reviewed by the student and emailed to their instructor as an answer key.

Anatomy Tests can serve like a simulated lab practical to reinforce students knowledge of anatomy with self-assessment tests. They can select from over 15,500 structures, and identification questions accompanies by nearly 600 full-color anatomical illustrations, cadaver images and radiographs. Student can select randomized tests of 20 questions each by body region and can review their responses and save results for comparison or review. Instructors can create tests and simulated lab practical exams easily and conveniently, based on body region and anatomical system.

The instructors version of A.D.A.M. Interactive Anatomy or A.D.A.M. Interactive Anatomy Lite includes capabilities that the Student Version does not. Following are some differences between these versions:

Curriculum Builder is a great way to integrate your text with customized images from AIA to create, organize, and package course materials, virtual laboratory exercises, classroom lecture presentations, and custom communication tools. With Curriculum Builder your classroom lectures, virtual laboratory exercises and more can be shared with your students electronically or posted using your school's learning management system.

Import and export capabilities - You can import 3rd party images and animations, and easily export customized images into PowerPoint and word processing applications, curricula, tests, and more.

Hide and lock viewer controls - Use hide and lock viewer controls to disable structure identification and display only what you want students to see.

Live lecture mode usability - Create dynamic live lecture presentations using the interactive and visual power of AIA online. The software can be used in class, and allows for annotations and modifications on-the-fly.

With new pre-built curriculum for 11 different body systems, and a Curriculum Builder Training Guide, you now have terrific examples giving you a sense of what is possible.

Annotate illustrations in Dissectible Anatomy, Atlas Anatomy, Clinical Illustrations, or even your own imported images easily with the advanced functionality of AIA online.

A.D.A.M. Interactive Anatomy is also an extensive content management system through the ability to export any Dissectible Anatomy, Atlas Anatomy, Clinical Illustrations, or even your own imported images with or without annotations for use in other classroom presentations or student handouts.

A.D.A.M. Interactive Anatomy is the perfect resource to enhance your anatomy and physiology studies. With the newly added content A.D.A.M. Interactive Anatomy is ideal if you are taking allied health, nursing, continuing medical education (CME) or other medical related courses requiring the study of clinical applications and concepts.

Online access to A.D.A.M. Interactive Anatomy is available for students in convenient one-year and six-month subscriptions. With the online version there are no hassles with software requirements or license codes, and you can access this incredible resource anytime, anywhere with simple username and password control.

Short on institution funds to provide A.D.A.M. Education Solutions? Your institution can make A.D.A.M. Interactive Anatomy, A.D.A.M. Interactive Anatomy Lite and A.D.A.M. OnDemand more affordable for students at no cost to your institution through our Student Materials Adoption Program and earn your own Instructors subscription for free.

Now you can include, as an additional resource, our award-winning A.D.A.M. OnDemand mobile learning programs directly within A.D.A.M. Interactive Anatomy or A.D.A.M. Interactive Anatomy Lite. The bundle of A.D.A.M. OnDemand with AIA adds over 20 instructional learning programs for understanding the anatomy or physiology of 11 different body systems. It is a terrific way to incorporate more instruction and physiology content, which is perfect for a flipped classroom or blended learning program. A.D.A.M. OnDemand Learning Programs resource includes the following:

Software

Minimum System Requirements

Recommended System Requirements

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A.D.A.M. Interactive Anatomy Online. - A.D.A.M. Education