Human Behavior

Syncing Data And Creative: Advertising’s Head And Heart – Forbes

Within advertising, a debate has raged for years about how to balance advertisings head (data, sales goals and competitive share) and its heart (evoking peoples emotions, touching peoples souls, creating inspiration and wonder).

The past decade has swung the pendulum heavily toward the head; as an industry, we have focused on first-party audiences, data lakes, programmatic pipes, return on ad spend and a grim determination to map every impression to a sale. In that march toward advertising determinism, we have worked to bring creativity to heel by connecting creative teams to centralized platforms that map consumer insights, journeys and behaviors to inform the creative process. Yet, the magic formula for A=B/C= a campaign that performs every time hasnt emerged from all this effort. Why not?

Maybe its because there is no magic formula and there never will be. Im reminded of Economics 101 classes where every problem begins with assume a perfect market, even though a perfect market doesnt actually exist. In advertising, weve tried to create a perfect market by:

1. Relying heavily on big longitudinal datasets that cluster people in high-level buckets that, while often accurate, dont capture a lot of nuance.

2. Building one size fits all creative assets where what gets put in a mobile ad, for example, is often a cut-down version of a 30-second television spot, rather than an asset created for a unique channel and user experience.

3. Creating an artificial divide between brand and demand, where a given channel or campaign or creative is designed for one purpose or the other and measured accordingly.

What if, instead, we embraced our imperfection? What if we made room for head and heart in every initiative and measured things accordingly? What if we acknowledged that we are humans selling to humans, and that there is alchemy in what we do that can be optimized and improved upon but not mass-produced?

I am not suggesting a return to the Mad Men era of The ad will work because the creative director said it would work. Im suggesting we all lean into the future where the agile and atomized use of data brings both head and heart to everything we do.

Think about how companies such as Spotify, Netflix and Amazon make use of data to customize content and help us navigate an endless sea of options. These companies generate massive amounts of data, but they apply it in real time to customize peoples experience, and they use a feedback loop to continuously improve outcomes. What if all advertising could be that responsive and intelligent? Wouldnt that improve both customer experience and ROAS?

As the general manager of analytics at an attention analytics company, I believe the future isn't as far off as some might think. But it does require some behavioral and infrastructure shifts in marketing behavior. Among them are:

1. An approach to ad measurement that includes human behavior signals. At my company, we call these signals digital body language, and we use them to understand how an ad is being received by the person to whom it is being served.

2. A data infrastructure that is agile and flexible enough to capture, process and react in real time so that advertisers and their partners can not only see whats happening, but also set up responses that adjust messaging, imagery and offers within a campaign and even within a given users session.

3. Creative assets that are uniquely formatted to capture the signal and optimized to the channel in which they are being served so that winning narratives can be more easily recognized and optimized quickly.

4. A relentless test-and-learn mindset that embraces atomizing each piece of the ad experience to identify the colors, images, headlines and offers that drive results, both individually and working together.

Embracing head and heart requires teams to have a healthy respect for both data and creative and to begin to truly unpack how data, creative and media interact to deliver meaningful consumer experiences. Doing that requires a true spirit of partnership that allows everyone to fail fast, regroup, learn and try again.

While advertising might be a gloriously imperfect science, by letting our heads develop the right data infrastructure to give us valuable and actionable real-time insights and letting our hearts focus on the big ideas that connect and inspire us, we can embrace that imperfection to drive better business results.

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Syncing Data And Creative: Advertising's Head And Heart - Forbes

Human Behavior

Rising temperatures could pose threat to spread of coronavirus – WJTV

Posted: Jun 19, 2020 / 01:10 PM CDT / Updated: Jun 19, 2020 / 01:10 PM CDT

RIDGELAND, Miss. (WJTV) During the early stages of the coronavirus pandemic, it was highly believed the heat could possibly help stop the spread of the virus. However, researchers say that is not enough.

Dr. Timothy Quinn of Quinn Healthcare explained the recent findings.

More researchers have added that humans have so little immunity to the virus. This is a new virus, so most of us have not been exposed. Our immune systems have not created enough antibodies, and then we dont have the vaccine, he said.

Health experts are still encouraging people to wear face masks and social distance.

I cannot overemphasize how important it is that we wear those masks. Human behavior has a very significant impact on the decrease spread of this virus, that includes social distancing, wearing a masks, washing your hands. Just following those guidelines that are suggested by the CDC, said Quinn.

Quinn also urged coaches to keep athletes hydrated as summer practices begin to kick-off across Mississippi.

Drink water before practice, during practice, after practice. Try to cut the hours or the time of practice to shorter intervals and try to practice during the cooler times of the day, such as early in the morning or later in the evening as much as possible to keep these young people safe.

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Rising temperatures could pose threat to spread of coronavirus - WJTV

Human Behavior

You put yourself at risk, but thats the job: Fall River doctor on front line of coronavirus fight – Fall River Herald News

FALL RIVER For weeks, Dr. Daniel Sousa slept in the she shed. Then he moved into the sunroom. But now the physician who has been on the front lines of treating COVID-19 patients is back in the house and ready to enjoy Fathers Day with his family.

The father of three children, daughter Scarlet, 8; sons Skiler, 12, and Sidney, 14, said his wife, Theresa, a stay-at-home mom, has been doing double duty as teacher since the schools closed, while hes been focused on treating COVID-19 patients.

Though its been a challenge he never imagined when he decided to become a pulmonologist and its far from over the first couple months were filled with uncertainty, recalled Sousa.

As one of the partners with Southcoast Health Pulmonary, Sousa and the other pulmonologists in the practice have been taking turns rotating shifts covering the ICU unit at Charlton Memorial Hospital, Tobey Hospital in Wareham and occasionally at St. Lukes Hospital in New Bedford.

Sousa said they had been watching what was going on in China and then it came on in this country at an exponential rate, well before the medical field was prepared for it. Suddenly their nerves were up as they saw the rates rising and then the closings started to happen mid-March. They started to realize they didnt have good therapy for it, as it was truly a novel coronavirus that was also extremely contagious, he recalled. We all started to think were going to be at risk to our families. Potentially were going to spread it to our loved ones: wives, children. And then a lot of us thought, OK, were in the thick of it, we signed up for this but its probably a matter of if not, when we get it, but please dont let me get it now because Im needed. So we kind of had that mentality, said Sousa.

Then their colleagues nurses and doctors started getting sick and Sousa said they had to intubate a doctor who contracted it. That really hyped up your perception of this, he recalled.

Thats when his thoughts turned to staying in the "she shed in the backyard as a way of keeping his family safe during those uncertain early days of COVID-19. Sousa moved into the shed, which also doubles as a mini pool house, outfitted with a futon, cable television, a refrigerator and an electric fireplace. I would eat dinner away from them and then when it was time to go to bed I would go hit the shed. After about three weeks I got sick of it, it was getting pretty lonely so then I started sleeping in the sunroom on an air mattress and I did that for about a week and then that got old, he recalled.

After a while he started going back into the house when he was five days clear of potentially dangerous situations, like his shifts covering the ICU.

In talking to his kids about the virus, he said statistically speaking, the risk to children is small and most children who get it have symptoms that are so mild they dont even know they have it. I said, youre going to be OK. If you get it, youll be fine its just your dad has to do this. I could get sick, but Ill be alright, he said. And then I said, you know what I do for a living, I take care of sick people.

Eight of the doctors at Southcoast Health Pulmonary rotate through the ICU at Charton Memorial Hospital, meaning they do one week every eight weeks. They also do one of 16 weeks at Tobey Hospital and a smattering at St. Lukes Hospital when they need help. Additionally each partner covers the COVID-19 ward every eight weeks at Charlton. When youre in the hospital, every day is different you dont know what youre going to see, he said.

Sousa joined the practice in 2004. A native of Lisbon, he immigrated to Providence when he 7 seven years old. Even as a kid he said he knew he wanted to be a doctor and having asthma as a child made him empathetic to people with breathing problems leading to his specialty as a pulmonologist. He moved to Fall River in 2004, when he joined Southcoast Health Pulmonary. Being fluent in Portuguese has been extremely handy in caring for patients, especially in this area of the state, he said.

Dealing with COVID-19 has been by far the toughest part of his career. I never want to go through this again. Its not just the medical part, its like one eye is closed and one hand is tied behind your back. The eye closed is that early on we couldnt get the testing done and when we did it took forever to get it back. And the hand behind your back is youre running as you go. You dont have a good attack plan. It takes a lot of supportive care to get people through but weve been through this to a lesser extent before in 2008/2009 when we had H1N1, he said. And during my residency training, AIDS was a terminal illness and we were taking care of AIDS patients and even then, you put yourself at risk, but thats the job. You signed up for it.

As a support system, the doctors at Southcoast Health Pulmonary have been texting each other, bouncing ideas back and forth as the set out to treat patients with COVID-19. First they tried hydroxychloroquinine because they were desperate, though they found it out didnt work. Then they turned to convalescent plasma, which was somewhat effective and now remdesivir is the latest treatment, he said.

Adding time to patient care, they have to do whats called donning and doffing, gowning up and putting on a vented hood for each patient visit. But the toughest part, he said, is the fact that families cant be there. Its hard that youre trying to express everything by a telephone call and you just dont have that face-to-face. Its hard to tell people that your loved one isnt doing well. Only when theyre dying are they allowed to come in the hospital to spend their last moments with them, said Sousa.

The most heartbreaking, he said, is seeing loved ones FaceTiming each other before the patient is put on a ventilator. At that moment theyre looking at each other and they know, that could be the last time I see you alive. Thats hard, probably the hardest part, he added.

But at the same, he said theyve had some great moments when theyve had a patient pull through after weeks of being in the ICU. One of those patients was Somerset resident Robert Ledo, who Sousa met a couple weeks into Ledo's lengthy stay in the ICU with an extreme case of COVID-19. I did a telehealth visit with him afterward and here he is sitting at his table at home and I said, I cant believe how good you look; you look amazing. That gives you the push that this is what you want to do for a living, said Sousa.

Though cases seem to be slowing down a bit locally, Sousa said he thinks COVID-19 going to be around for a while. Being a corona class virus it rears up in the winter so it will behave in that pattern, said Sousa, adding a lot it will depend on human behavior and the risk of spreading it increases as people get complacent and let their guard down. While he understands the cause behind the recent Black Lives Matter demonstrations, for instance, Sousa said he worries about the crowds spreading the coronavirus. Its going to be with us through the winter season and it will rotate around the planet, so until we get a good therapeutic or a good vaccine, weve got to hunker down.

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You put yourself at risk, but thats the job: Fall River doctor on front line of coronavirus fight - Fall River Herald News

Human Behavior

It takes teamwork, to both get the job done and take a break from the job – ThePrint

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People are feeling burned out. Months of uncertainty, homeschooling and strangely hard-to-decline video callshave taken their toll. Perhaps youve lost your ability to focus at work, and you cant even muster the motivation to care. Maybe you just feel really, really tired. Theres a natural impulse to blame this malaise on a very obvious aspect of the new circumstances many of us are facing: technology-enabled isolation amid a global pandemic and a barrage of heartbreaking news.

We struggle tostop rage-scrolling social media, but the news there has been so troubling that it feels wrong to look away. Nonstop video calls areexhausting, whether they are work meetings or virtual happy hours. Teleworking has its upsides, but one drawback is that it can be hard to switch off. The data show that each day, were working longer hours aboutthree hours longerthan we were before offices closed. Being separated from our bosses creates pressure to reply to messages instantaneously, to prove were not goofing off. Even after hours, our phones whisper about emails unread and buzz with messages from hyperactive group chats.

Most of the solutions on offer feelflimsy in comparison: Useenvironmental cues like clothing and locationto signal to your brain when youre working from home and when youre simply at home. Avoid the anxiety of late-night Twitter by leaving your phone outside the bedroom. Manage the unending email deluge with any number ofhacks and tips. When all else fails, take a few mindful breaths.

Somehow, such efforts dont really feel commensurate to the moment if they ever did. And although theres something to be said for steps you can take without consulting anyone, the most effective changes are those you make jointly with others your team, your boss, your family.

That was one lesson learned by the employees studied by Leslie Perlow, a professor at Harvard Business School. In her research, teams of exhausted consultants sought to regain work-life balance by ensuring that every team member could take predictable time off. To hold themselves accountable, they made that unplugged time mandatory. Working toward this goaltogetherwas ultimately what produced happier, less-burned out employees. It also improved communication between team members and resulted in higher-quality output for clients.

Collective action is the only way to re-establish healthy norms for communication technology. If your whole team spends the weekend emailing each other, it doesnt do much good for one person to take adigital sabbath. Emails will continue to fly, and the person who opted out unilaterally will miss important decisions or be tarred as a slacker, or both.

Instead, decide as a group when everyone needs to be online and when responses arent expected. You should also decide on how to communicate during off hours. Checking email during your leisure time is one of those annoying habits that can suck you back into work when you need to be doing something else. So choose, collectively, to reserve email for non-timely messages and to handle emergencies over the phone. That takes the pressure off of everyone to keep checking their inboxes just in case.

New norms can also help during work hours. You and your team could decide to keep one day a week free of meetings and, to the extent possible, messages, so that everyone can focus on heads-down work this is much easier to do without the pressure to respond to every email, slack or IM. Again, thissolution is best adopted jointly: If youre blocking out Fridays as a meeting-free day, but Juan chooses Mondays and Tina chooses Wednesdays, thats obviously not going to work. Instead, agree on one (or even two!) days a week and work together to keep them clear.

Of course, these techniques can also make a difference in your social and familial communications, since were often using thesame tech tools to talk with friends and family. If multi-hour, 10-person Zoom bonanzas are starting to wear you down, is that because of some problem inherent in Zoom, or because certain participants dont recognize when their stream of consciousness has run its course? Either way, its a tech-enabled problem that can be solved through human behavior agreeing to limit the conversation to an hour, appointing someone to moderate it, or bowing out of the mega-call and catching up with people one on one, over the good ol fashioned telephone.

Joint solutions like these emphasize that the burnout were experiencing isnt our problem to solve alone and isnt the inevitable result of our situation or technology. Its just how were wired.

Keeping up with information and not wanting to disappoint people arecommon human traits. A quick look back at history shows just how persistent these urges are, regardless of what technology is being used. When the printing press was invented, for example, anxiety aboutinformation overloadspiked Is there anywhere on earth exempt from these swarms of new books? Erasmus despaired,in 1525. Weve long felt besieged by correspondence: In 19th century London, letters could be deliveredup to 12 times daily; same-day delivery (and near-instant replies) were expected.

Working from home may feel new to many of us, but it too has a long history. In fact, as my colleague Justin Fox has pointed out, work-from-home rates arestill lowerthan they were in the 1960s.

Always-on technology and remote work didnt create burnout, but they can make it tougher to break free from it. When the usual barriers keeping work and other commitments in their place are gone, more human effort is required to contain them. Let that be ateam effort, and its much more likely to succeed.- Bloomberg

Also read: When work moved home during Covid, so did toxic workplace harassment

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It takes teamwork, to both get the job done and take a break from the job - ThePrint

Genetics

A geneticist advocates for diversity and fixing his industry in the process – STAT

Over the past few weeks, 23andMe and other genetic testing companies have made headlines for releasing candid statements acknowledging that their field and their products are too white. Its a problem with which geneticist Tshaka Cunningham is all too familiar.

As executive director of the nonprofit Faith Based Genetic Research Institute, Cunningham has traveled widely to speak at Black churches about the value of genetic research. And as co-founder and chief scientific officer of a genetics startup called TruGenomix, hes working to recruit more diverse cohorts to build a genetic test for gauging risk of developing PTSD.

Cunningham recently called in to STATs podcast, The Readout LOUD, to discuss genetics and racial inequity and what needs to be done to make the field actually reflect the worlds diversity.

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The transcript of the conversation has been lightly edited for clarity.

So, Tshaka, what do you make of the reckoning that weve seen in the past couple weeks from 23andMe and other genetics companies on these issues?

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You know, I think its actually a really good thing. I was glad to see it from the highest levels from these companies acknowledging an issue that many of us in the research community have known about for quite a long time, which is this lack of representation of diverse genomes in all of our studies and products. Im glad its starting to get deeper attention because I think it is a key issue thats going to impact the effectiveness of all of these tools over time.

Im looking forward to seeing some positive things that they will do to address it. So, you know, the first step is admitting you have a problem and then you go through the steps to rehabilitate. Im hoping that some positive things will come out of this.

What kinds of questions about genetics do you hear from the communities you speak with?

All kinds of questions. And first of all, I say, you know, the work that were doing with the Faith Based Genetic Research Institute is very unique in that we are bringing together individuals from the faith communities with scientists who are also people of color, and one of our guiding principles in the work that we do in the community is called the honest broker philosophy. That is, those of us who are imparting the information to the community are also from the community. And what we found is that it really helps us establish a better bond of trust for folks to be able to receive the information.

Some of the questions that we get when we talk about the value and the benefits of genetic research is the first questions are, you know, are they going to use it to hurt me? Thats the first question we get a lot from African American participants. And, you know, what will they do with the information? Theres a fair bit of distrust out there. And some of it is quite warranted from past transgressions of the medical establishment on the African American community. But once you sort of talk through those issues with folks and really kind of allow them to see some of the potential benefits, then you start getting a high level of interest.

So lets say 23andMe, for example, or one of the large companies, were to call you and ask for advice on what to do to make their products less Eurocentric and more inclusive. What would you tell them?

Start by making sure that your team, your executive team specifically, is representative of the community. A lot of companies sort of say, well, we cant find them. Any company needing to find a talented minority geneticist give me a call. Ive got a long list.

The second step would be to really use some of your resources to sponsor more research in this area. I mean, part of the challenge is also a financial and economic challenge. When you think about the economic disparities that have existed in America based on racial lines you know, the average African American has seven times less wealth than the average Caucasian. So they might not have even a hundred bucks to spend on something like genetic testing that could benefit them.

And then theres also the messaging. I think to the extent that these companies could help organizations like ours, the Faith Based Genetic Research Institute, other academic institutions, with messaging about the importance or the potential benefits of this, that would be great.

Now, I know thats a fine line that they have to walk because, you know, you dont want to seem coercive. But at the same time, I think trying to really do authentic outreach to the community would start with having more of your employees be from the community and then having a dedicated effort of that kind of outreach within your operation.

One of the more controversial questions in this conversation is around compensation. So what do you think? Do you think that 23andMe should pay people in the Black community and other underrepresented populations for their data?

I believe anybody that contributes their data should have the opportunity to get paid for it if its used. I do not believe in coercing someone to contribute their data with payment. But if Im an individual who has contributed and then you go and use my my data lets say a pharma company buys access to my data and I dont see any benefit from it, then that feels a bit un-American and I just dont feel like its fair. But thats my personal opinion.

So lets talk a little bit about polygenic risk score tests, which really encapsulate the diversity problems in genetics. So, for readers who are unfamiliar with them, these are tests that gather multiple genetic variants together and use them to predict someones chances of developing a disease. So far, many commercial polygenic risk score tests have come off warnings that theyre not very accurate or are even useless in people who are not of European ancestry. But your startup, TruGenomix, is working on a polygenic risk score test to try to gauge risk for developing PTSD. And youre trying to build the test using more diverse data. Tell us about your approach.

Ive recognized the importance of diversity in your datasets. From my earliest days, when I was at the Department of Veterans Affairs, we had a large genomics project called the Million Veteran Program. And part of my contribution to that project was to make sure that minority veterans participated. And so we actually went to great effort to ensure that. And that project has done very well to the credit of the VA, to recruit minority veterans. So that data set is going to provide some rich understanding, or has that potential to provide rich understanding, in polygenic risk for minority communities.

I took some of what I learned there from having to really take the time to do the outreach to the communities, to make sure that the end products are representative. I think that is just core to our actual DNA as a company. I think part of that has to do with the fact that were one of the very few minority-owned genomics companies in the country right now. This was top of mind for us. We wanted to make sure that whatever products we were putting out, the polygenic risk related to all communities, specifically the African American community, which my founders and I come from. It was just a very important thing for us to do not only for societal and ethical reasons, but also for scientific integrity reasons, because as a scientist, I dont believe in putting out products that arent probably applicable to all communities.

So why havent other makers of polygenic risk score tests taken this more holistic approach?

You know, I cant speak for them. I mean, I dont know. Thats a question that I have. I would hope that they take a deeper look at it. Maybe their market calculations were, OK, the people using genetic tests now tend not to be people of color. And therefore, we dont need to care about them. I dont know. Youll have to ask them that question.

All I could say is that I hope that all of the companies that are making these kinds of tests really take diversity seriously. Ive given lectures around diversity and genetics in the past. The majority of the DNA in the world is not of Caucasian origin. Its actually of Asian origin. And then African and Latino. And then Caucasians are only maybe about 14% of all the DNA out there just based on population. So when you think about it in that respect, if you really want to have a genome that is globally applicable, then youd really need to focus on its diversity.

Tshaka, thank you for coming on the podcast today.

Great. Its great being with you all today.

Theresa Gaffney contributed to this report.

This is a lightly edited transcript from arecent episodeof STATs biotech podcast, The Readout LOUD. Like it?Consider subscribing to hear every episode.

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A geneticist advocates for diversity and fixing his industry in the process - STAT

Genetics

Listen: The latest on Covid-19, vaccine politics, and diversifying genetics – STAT

Can a vaccine be an October surprise? Are journal publishers running a racket? And why is genetics so white?

We discuss all that and more this week on The Readout LOUD, STATs biotech podcast. First, we run through a busy week in news, discussing the results of a major study on Covid-19 treatment, an escalating fight in the publishing world, and the drug industrys biggest-ever IPO. Then, physician and health care policy expert Ezekiel Emanuel joins us to discuss his nightmare scenario: President Trump, desperate for re-election, forces the approval of an ineffective coronavirus vaccine. Finally, we talk to geneticist Tshaka Cunningham about the deep racial inequities in the field of genomics and what can be done to correct them.

For more on what we cover, heres the news on a potential Covid-19 treatment; heres more on the the fight over academic publishing; heres a look at inequality in genetics; and heres the latest in STATs coronavirus coverage.

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Well be back next Thursday evening and every Thursday evening so be sure to sign up onApple Podcasts,Stitcher,Google Play, or wherever you get your podcasts.

And if you have any feedback for us topics to cover, guests to invite, vocal tics to cease you can emailreadoutloud@statnews.com.

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Genetics

Researchers identify environmental components that affect gene expression in cardiovascular disease – The South End

A research team led by Francesca Luca, Ph.D., associate professor of Wayne State Universitys Center for Molecular Medicine and Genetics, has published a study that annotated environmental components that can increase or decrease disease risk through changes in gene expression in 43 genes that could exacerbate or buffer the genetic risk for cardiovascular disease. Their results highlight the importance of evaluating genetic risk in the context of gene-environment interactions to improve precision medicine.

Interpreting Coronary Artery Disease Risk Through GeneEnvironment Interactions in Gene Regulation was published in Genetics, the journal of the Genetics Society of America.

The study, said Dr. Luca, also of the WSU Department of Obstetrics and Gynecology, illustrates that combining genome-wide molecular data with large-scale population-based studies is a powerful approach to investigate how genes and the environment interact to influence risk of cardiovascular disease.

By identifying regions of DNA important for endothelial cell response to different common environmental exposures, the researchers discovered that caffeine can influence the risk of cardiovascular disease. The study demonstrates the potentially beneficial and/or detrimental effects of certain environmental exposures on the cardiovascular disease risk differ depending on individual DNA sequence.

The study focused on cardiovascular disease, Dr. Luca said, because it is the leading cause of death, both in the United States and worldwide. Also, the disease is highly multifactorial, with large contributions from both environmental and genetic risk factors. By treating endothelial cells under a controlled environment, we can discover how these genetic and environmental risk factors influence each other at the molecular level, she said. Our lab has developed expertise in cardiovascular research, with additional projects using endothelial cells to develop new assays to test the regulatory activity of genetic variants. The approach outlined in this paper can be applied to many different diseases; for example, our lab has also focused on how bacteria in the human gut affect gene expression in the colon, and also on the effect of psychosocial stress on asthma.

While the work identified regions of the genome important for how endothelial cells respond to the environment and can influence the risk of cardiovascular disease, the researchers do not yet know exactly which genetic variants are directly responsible. A former graduate student, Cynthia Kalita, developed an assay to test thousands of genetic variants for gene regulatory activity. The researchers can test the variants discovered in their study using that assay to validate and explore the mechanisms by which they exert their effects, Dr. Luca said. They also are developing computational/statistical methods that can yield better personalized risk scores.

We have extended our approach to study cardiomyocytes, which are the muscle cells of the heart. Healthy heart tissue is difficult to obtain, so we have collaborated with researchers at the University of Chicago to derive cardiomyocytes from stem cells, Dr. Luca said. This will allow us to shift our focus from the vasculature to the heart itself, where we can study diseases like cardiomyopathies and arrhythmias.

As the cost of DNA sequencing continues to decrease, Dr. Luca expects that genetic testing will play a greater role in preventive health care. To fully realize the potential of precision medicine, we need to consider both genetic and environmental risk factors of disease, and how they interact. While there are already direct-to-consumer tests that prescribe an individualized diet based on DNA, these products currently offer no demonstrated clinical value. However, with very large numbers of individuals for whom we have both DNA sequencing and information on diet and lifestyle, we may one day be able to offer better recommendations.

Others involved in the study included Anthony Findley, an M.D./Ph.D. student; Allison Richards, Ph.D., a research scientist; Cristiano Petrini, of the Center for Molecular Medicine and Genetics; Adnan Alazizi, lab manager; Elizabeth Doman, of the Center for Molecular Medicine and Genetics; Alexander Shanku, Ph.D., research scientist; Gordon Davis, of the Center for Molecular Medicine and Genetics; Nancy Hauff, Department of Obstetrics and Gynecology; Yoram Sorokin, M.D., professor of Obstetrics and Gynecology; Xiaoquan Wen, of the Department of Biostatistics at the University of Michigan; and Roger Pique-Regi, Ph.D., associate professor of the Center for Molecular Medicine and Genetics, and of the Department of Obstetrics and Gynecology.

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Researchers identify environmental components that affect gene expression in cardiovascular disease - The South End

Genetics

Human Genetics Market Analysis with Key Players, Applications, Trends and Forecasts to 2026 – Farmers Ledger

The Human Genetics market report Added by Market Study Report, LLC, enumerates information about the industry in terms of market share, market size, revenue forecasts, and regional outlook. The report further illustrates competitive insights of key players in the business vertical followed by an overview of their diverse portfolios and growth strategies.

The research report on Human Genetics market offers a thorough analysis of this industry vertical, while evaluating all the segments of the market. The study provides significant information concerning the key industry players and their respective gross earnings. Additionally, crucial insights regarding the geographical landscape as well as the competitive spectrum are entailed.

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In-depth analysis of the regional scope of Human Genetics market:

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Other insights associated with the Human Genetics market research report:

This report considers the below mentioned key questions:

Q.1. What are some of the most favorable, high-growth prospects for the global Human Genetics market?

Q.2. Which products segments will grow at a faster rate throughout the forecast period and why?

Q.3. Which geography will grow at a faster rate and why?

Q.4. What are the major factors impacting market prospects? What are the driving factors, restraints, and challenges in this Human Genetics market?

Q.5. What are the challenges and competitive threats to the market?

Q.6. What are the evolving trends in this Human Genetics market and reasons behind their emergence?

Q.7. What are some of the changing customer demands in the Human Genetics Industry market?

Table of Contents:

Executive Summary: It includes key trends of the Human Genetics market related to products, applications, and other crucial factors. It also provides analysis of the competitive landscape and CAGR and market size of the Human Genetics market based on production and revenue.

Production and Consumption by Region: It covers all regional markets to which the research study relates. Prices and key players in addition to production and consumption in each regional market are discussed.

Key Players: Here, the report throws light on financial ratios, pricing structure, production cost, gross profit, sales volume, revenue, and gross margin of leading and prominent companies competing in the Human Genetics market.

Market Segments: This part of the report discusses about product type and application segments of the Human Genetics market based on market share, CAGR, market size, and various other factors.

Research Methodology: This section discusses about the research methodology and approach used to prepare the report. It covers data triangulation, market breakdown, market size estimation, and research design and/or programs.

For More Details On this Report: https://www.marketstudyreport.com/reports/global-human-genetics-market-size-status-and-forecast-2020-2026

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Human Genetics Market Analysis with Key Players, Applications, Trends and Forecasts to 2026 - Farmers Ledger

Genetics

In Brief This Week: Thermo Fisher Scientific, Myriad Genetics, Fulgent Genetics, and More – 360Dx

NEW YORK Thermo Fisher Scientific said this week that the US Food and Drug Administration has granted Breakthrough Device Designation for its Oncomine Precision Assay to identify low-grade glioma patients with isocitrate dehydrogenase 1 and 2 mutations and who may be eligible for treatment with vorasidenib (AG-881). The assay is designed to run on the Ion Torrent Genexus sequencing platform. Thermo Fisher is codeveloping a companion diagnostic for vorasidenib with Agios Pharmaceuticals.

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In Brief This Week: Thermo Fisher Scientific, Myriad Genetics, Fulgent Genetics, and More - 360Dx

Genetics

Podcast: The dark connection between cancer research and the eugenics movement – Genetic Literacy Project

Geneticist Dr. Kat Arney explores the stories of two women one a scientist fascinated by dancing mice, the other a seamstress with a deadly family legacy who made significant contributions to our understanding of cancer as a disease driven by genetic changes. Yet while their work paved the way for lifesaving screening programs for families, it was used by some as justification for eugenics the idea of removing genetic defectives from the population.

Born in Minnesota in 1879, Maud Slye was a cancer pathologist who dedicated her career to studying patterns of cancer inheritance in more than 150,000 mice. But as well as being a dedicated scientist (as well as a part-time poet), she was also wedded to eugenic ideas, suggesting that If we had records for human beings comparable to those for mice, we could stamp out cancer in a generation. At present, we take no account at all of the laws of heredity in the making of human young. Do not worry about romance. Romance will take care of itself. But knowledge can be applied even to romance.

While her ideas were controversial, Slyes work earned her a gold medal from the American Medical Society in 1914 and from the American Radiological Association in 1922. She was also awarded the Ricketts Prize from the University of Chicago in 1915 and an honorary doctorate from Brown University in 1937. She was even nominated for a Nobel prize in 1923.

Over the decades since Slyes death in 1954, weve come to understand that the hereditary aspects of cancer susceptibility are much more complicated than she originally suggested, although her work was vital in establishing inherited gene variations as an essential thread of cancer research.

Running parallel to Slyes work in mice was the research carried out by Aldred Warthin, a doctor working at the University of Michigan in Ann Arbor. One day in 1895, a chance meeting between Warthin and a local seamstress, Pauline Gross, set the two of them off on a 25-year-long quest to understand why so many members of Paulines family had died from cancer at a young age.

Pauline spent years compiling detailed family histories, enabling Warthin to trace the pattern of inheritance through Family G, as it became known. Like Slye, Warthin was a fan of eugenic ideas, describing Paulines family as an example of progressive degenerative inheritance the running-out of a family line through the gradual development of an inferior stock.

He was also quoted as saying in a 1922 lecture: Today it is recognized that all men are not born equal. We are not equal so far as the value of our bodily cells is concerned.

Perhaps as a direct result of growing public concern about eugenics, Warthins work fell out of favor. Paulines detailed genealogy lay undisturbed in a closet in the university until the 1960s, when American doctor Henry Lynch and social worker Anne Krush rediscovered her work and continued extending and investigating Family G.

Nearly a decade on from that first meeting between Pauline and Warthin, researchers finally pinned down the underlying genetic cause of this deadly legacy: an inherited variant of the MSH2 gene, which normally repairs mismatched DNA strands. Today, members of Family G and others around the world carrying dangerous variants in mismatch repair genes can undergo genetic testing, with a range of preventative and screening options available.

The story of Pauline and Family G, and the impact that their genetic legacy has had on the family down the generations, is beautifully told in the book Daughter of Family G, a memoir by Ami McKay.

Full transcript, links and references available online atGeneticsUnzipped.com

Genetics Unzippedis the podcast from the UKGenetics Society,presented by award-winning science communicator and biologistKat Arneyand produced byFirst Create the Media.Follow Kat on Twitter@Kat_Arney,Genetics Unzipped@geneticsunzip,and the Genetics Society at@GenSocUK

Listen to Genetics Unzipped onApple Podcasts(iTunes)Google Play,Spotify,orwherever you get your podcasts

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Podcast: The dark connection between cancer research and the eugenics movement - Genetic Literacy Project