Neuroscience (PhD) | School of Life Sciences

Two lecture courses constitute the core curriculum in the first year:

NEU 555 Cellular and Molecular Neuroscience (6 credit hours)* *Course is crosslisted with BIO. Neuroscience students need to register for the NEU prefix. Course is only offered in the fall semesters.

NEU 556 Systems Neuroscience (4 credit hours)* *Course is crosslisted with BME. Neuroscience students need to register for the NEU prefix. Course is only offered in the spring semesters.

The core courses are designed for students who already have a background in basic Neuroscience. The course sequence that has two major goals. One is to expose students to advanced, cutting-edge research from all levels of analysis in Neuroscience - that is, from molecular through systems-level processes, including how those processes affect behavioral and cognitive processes. A second goal will be to introduce students to application of basic and practical knowledge in biomedical settings.

The courses consist of modules led by faculty members who specialize in those areas of research. Each module is one to two weeks in length, consisting of both lecture and translational' components. Modules are taught in ASU classrooms and in facilities at ourClinical Partner institutions. In both types of locations, part of each module may consist of tours of laboratories and clinical facilities as well as discussions with clinicians and neurosurgeons. This exposure in particular will help to provide an overview of major interdisciplinary projects that are currently underway at ASU and at the Clinical Partner Institutions. It will also provide an opportunity for students to observe firsthand how team-oriented translational projects can be implemented to help solve problems in biomedicine that have a direct societal impact.

This list of ASU courses is subject to change. Courses may not be available each semester or academic year. New courses are being developed and you are encouraged to propose course and seminar topics to participating faculty.

BIO 598: Neuroscience, Ethics and the Law (3) Meets for 15 weeks (full semester). Instructors: Betsy Grey (Law) and Jason Robert (SOLS)

BIO 611: Current Topics in Responsible Conduct of Research (RCR) in Life Sciences (1) Meets for 5 weeks. Instructor: Karin Ellison

Bio 611: Current Topics in Responsible Conduct of Research (RCR) in Life Sciences (1) Meets for 15 weeks (full semester). Instructors: Betsy Grey (Law) and Jason Robert (SOLS)

BME 451: Cell Biotechnology Laboratory (4) Mammalian cell culture techniques including mouse embryonic stem cells, the use of biorectors, cell fractionation and digital video imaging.

BME 520: Bioelectric Phenomena (3) Study of the origin, propagation and interactions of bioelectricity in living things; volume conductor problems, mathematical analysis of bioelectric interactions, and uses in medical diagnostics.

BME 521: Neuromuscular Control Systems (3) Overview of sensorimotor brain structures. Application of nonlinear, adaptive, optimal and supervisory control theory to eye-head-hand coordination and locomotion.

BME 524: Fundamentals of Applied Neural Control (3) Fundamental concepts of electrical stimulation and recording in the nervous system with the goal of functional control restoration.

BME 532: Prosthetic and Rehabilitation Engineering (3) Analysis and critical assessment of design and control strategies for state-of-the-art medical devices used in rehabilitation engineering.

BME 551: Movement Biomechanics (3) Mechanics applied to the analysis and modeling of physiological movements. Computational modeling of muscles, tendons, joints, and the skeletal system, with application to sports and rehabilitation.

BME 568: Medical Imaging (3) CT, SPECT, PET and MRI. 3-D in vivo measurements. Instrument design, physiological modeling, clinical protocols, reconstruction algorithms and quantitation issues.

BME 598: ST Integrative Neuroscience (3)

BME 598: ST Research Ethics/Law (2-3)

BIO 451: Cell Biotechnology Laboratory (4) Mammalian cell culture techniques, including mouse embryonic stem cells, the use of bioreactors, cell fractionation, and digital video imaging.

BIO 465: Neurophysiology (3) Detailed treatment of cellular and organismal neurophysiology and nervous system function.

BIO 467: Neurobiology (3) Introduction into basic nervous system anatomy and function.

BIO 508: Scientific Data Presentation (2) Techniques necessary for presentation of scientific data used in journal publications, grant proposals, and visual presentations.

BIO 515: Science, Technology and Public Affairs (3) Explores the political, economic, cultural, and moral foundations of science and technology policy and governance in democratic society.

BIO 550: Advanced Cell Biology (3) Applies contemporary electron microscopic and biochemical/molecular techniques for studying eukaryotic cell functions. Mechanisms of intracellular protein trafficking.

BIO 551: Biomembranes (3) Structure and function of biological membranes, emphasizing synthesis, fluidity, exocytosis, endocytosis, and cell responses to hormones and neurotransmitters.

BIO 591: Responsible conduct of research (3) The class is designed to introduce graduate students to ethical issues in the research environment. Topics will include skills needed for success in graduate school and beyond, ethical issues in data handling, authorship, human genetics, conflict of interest, mentoring, experimental animals and human subjects, and other issues. Faculty facilitators will participate in discussing case studies and students will develop case studies based on their own experiences.

BIO 598: Developmental Neurobiology (6)* *Course prefix will change to NEU 557 beginning Fall 2011 This course is designed to examine the Development of the Nervous System. The class starts with neural induction, birth order, NS system axis formation, then goes to pathfinding, dendritic growth, synaptogenesis. This is followed by synapse elimination and programmed cell death. Finally, excitability homeostasis, neural circuit development, and Rett and Fragile X will be covered as two examples for neurodevelopmental diseases.

BIO 569: Cellular Physiology (3) Emphasizes the molecular basis for cell structure and function.

APM 530: Mathematical Cell Physiology (3) Alternate Fall or Spring Mathematical modeling of dynamical aspects of cell physiology. Diffusion, membrane transport, intracellular calcium channel kinetics, calcium oscillations and waves.

APM 531: Mathematical Neuroscience I (3) Fall Mathematical modeling of electrochemical processes in nerve cells. Dendritic modeling, dendritic spines and synaptic plasticity, bifurcation analysis of excitable membrane models, deterministic and stochastic methods for threshold dynamics and bursting, relaxation oscillations. You should have taken a previous graduate-level PDE course.

APM 532: Mathematical Neuroscience II (3) Spring Mathematical modeling of systems neuroscience. Network dynamics, coupled phase oscillators, central pattern generators, neural coding, learning and memory. You should have taken advanced ordinary differential equations and also taken APM 530 or APM 531 prior to enrolling in this course.

PSY 426: Neuroanatomy (4) fall Structure and function of mammalian brain, including sheep brain dissection (cross-listed with 591).

PSY 425: Biobasis of Behavior (3) spring

PSY 470: Psychopharmacology (3) select semesters

PSY 512: Advanced Learning (3) select semesters

PSY 524: Advanced Physiological Psychology (3) select semesters Contributions of physiological processes and brain function to fundamental behavioral processes.

PSY 528: Sensation and Perception (3) select semesters Principles of sensory and perceptual processes, emphasizing research literature.

PSY 573: Psychopathology (3) - fall Theory and research relating to the contribution of psychological, social, physiological, and genetic factors to the development and persistence of abnormal behavior.

PSY 591: Neuroanatomy (4) fall Structure and function of mammalian brain, including sheep brain dissection (cross-listed with 426).

PSY 591: Neurobiology of Learning and Memory (3)

PSY 591: Neuropsychopharmacology (3) select semesters

PSY 591: Grant Writing and Professional Development (3) select semesters

PSY 624: Clinical Neuroscience (3) select semesters Examines the biological underpinnings of psychological disorders at the molecular, cellular, and system levels (e.g., schizophrenia, depression, anxiety). Lecture, pro-seminar.

PSY 555: Experimental and Quasi-Experimental Designs for Research (3) select semesters Reviews research techniques. Analyzes lab and field research; applications to specific topics.

SHS 513: Neurophysiology of the Auditory System (3) fall or spring Focuses on the neurophysiology of the normal auditory system and on changes associated with hearing loss. Lecture, discussion, demonstrations. Prerequisite: instructor approval.

SHS 519: Auditory Pathologies and Disorders (3) Familiarizes students with major diseases, pathologies, and disorders of the human auditory system. Lecture, discussion, case studies, demonstrations, field trips, seminar, student.

SHS 520: Otoneurologic Applications in Audiology (3) Advanced otologic, neurologic, and audiologic approaches in the differential diagnosis of peripheral and central disorders of the auditory system. Lecture, lab, discussion, case studies, seminar, student presentations.

SHS 545: Speech Perception by the Hearing Impaired (2) Focuses on the perception of speech by normal-hearing and hearing-impaired listeners. Lecture, discussion, case studies, seminar, student presentations. Prerequisite: instructor approval.

SHS 555: Cochlear Implants The design and function of implantable neural prostheses for the restoration of hearing in adults and children.

SHS 567: Neural Bases of Communication Disorders (3) Neuroscience and its application to matters of normal and disordered communication.

SHS 575: Aphasia and Related Neurogenic Language Disorders (3)Assessment and treatment of acquired neurolinguistic impairment.

SHS 576: Neuromotor Speech Disorders Neurophysiology, diagnosis, and treatment of motor speech disorders; theory and models of normal and disordered speech production.

SHS 581: Right Hemisphere Syndrome, Traumatic Brain Injury, and Dementia (3) Studies the nature, characteristics, and clinical management of cognitive and communicative impairments accompanying right hemisphere damage, TBI, and dementia.

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Neuroscience (PhD) | School of Life Sciences

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