Category Archives: Physiology

Former INL researcher named to National Academy of Engineering – East Idaho News

The following is a news release from Idaho National Laboratory.

Dr. Frank Roberto, recently retired from Idaho National Laboratory (INL), has been elected into the National Academy of Engineering (NAE), one of the most prestigious distinctions an engineer can receive.

Roberto is currently senior manager for process innovation at Newmont Corporations Malozemoff Technical Facility in Englewood, Colorado. He worked at INL from 1988 to 2012, and his affiliation with the lab continued until 2019.

Roberto was nominated to the academy for advancing biotechnical applications for environmentally responsible mine production.

The NAE is one of three academies affiliated with the National Academies of Sciences, Engineering and Medicine, founded in 1863 to marshal the energy and intellect of the nations critical thinkers to respond to policy challenges with science, engineering and medicine at their core. Roberto was elected to the academys section on Earth Resources, which studies issues relevant to the supply, delivery and associated impacts of hydrocarbon, metallic and nonmetallic mineral resources and mineral and nonmineral energy resource systems.

In the nearly 25 years he spent at INL, Roberto progressed to the rank of Directorate Fellow, managing diverse research projects and technical teams in the biological sciences, specializing in microbiological techniques for metallurgical leaching (biomining). He participated on editorial boards of microbiology-related journals for professional societies, served on state and federal technical and scientific committees, and chaired the U.S. Department of Energys Biosafety Working Group within the Emergency Management IssuesSpecial Interest Group (EMI-SIG) Subcommittee on Consequence Assessment and Protective Actions (SCAPA). He also served as DOEs liaison to the American Biological Safety Association. In 2018, he became a registered member of the Society for Mining, Metallurgy & Engineering.

In the years I worked with Frank, I found him to have extraordinary insights into microbiology and metallurgy, said Dr. Vicki Thompson, a longtime colleague and distinguished staff engineer in INLs Biological and Chemical Processing Department. I cant think of anyone more deserving of this honor than he is.

Each year, academy members vote on candidates whom they judge to have made outstanding contributions to engineering research, practices or education. Nominations are made confidentially by existing members and must include three recommendations. The ballot is set in December and the final vote for membership occurs during January.

In 2020, 87 members and 18 international members were voted into the NAE, bringing total membership to 2,309 and the number of international members to 281. Individuals in the newly elected class will be formally inducted during a ceremony at the NAEs annual meeting in Washington, D.C., on Oct. 4.

Roberto earned his doctorate in biochemistry (plant physiology emphasis) from the University of California, Riverside and performed postdoctoral research in molecular plant pathology with Dr. Tsune Kosuge at the University of California, Davis. He is the second engineer with a longtime INL association to have been voted into the NAE. Kathryn McCarthy, formerly of INL and now vice president for research and development at Canadian Nuclear Laboratories, was elected in 2019.

INL is one of the U.S. Department of Energys (DOE) national laboratories. The laboratory performs work in each of DOEs strategic goal areas: energy, national security, science and environment. INL is the nations center for nuclear energy research and development. Day-to-day management and operation of the laboratory is the responsibility of Battelle Energy Alliance.

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Former INL researcher named to National Academy of Engineering - East Idaho News

Low-intensity interval training can be as effective as HIIT but only if you spend more time working out – Metro Newspaper UK

Bradley Elliott, lecturer in physiology, University of Westminster

THOUGH we know exercise is important for our overall health, and that more is typically better, many of us dont have hours a day to devote to working out. This might be why fitness regimes like high-intensity interval training (HIIT) have become so popular in recent years.

Not only does HIIT promise to improve overall health and fitness, it can also be done in a short amount of time. But HIITs intensity might not be for everyone which is why slower, less intense workouts have started to gain popularity.

HIIT requires you to work all out for brief periods of 30-45 seconds, interspersed with recovery periods of about five minutes, repeated approximately 2-4 times. Because its done at such a high intensity, you can have a successful workout in as little as 15-20 minutes. It can even be done by older people and those with chronic health conditions like diabetes.

Though it might sound easy, those 30 seconds can feel like they last for ever if youre exercising as intensely as you possibly can. Simply put, HIIT can hurt and it might not be good for everyone.

Though uncommon, in my lab weve had people be ill, feel faint and very rarely pass out during a single 30-second super-maximal exercise. While the benefits still outweigh the risks for most people, HIIT has also been linked to greater risk of injury.

But LIIT (low-intensity interval training) has become a recent exercise phenomenon that claims you can still achieve similar fitness results to HIIT, but with lower risk of injury. Though there is currently no research on the effects of LIIT workouts, the idea is that you still perform exercises in intervals, but these exercises are done at a lower intensity and with shorter rest time in between.

Given the lack of research, to know if LIIT works we need to look at studies that have compared the effects of doing the same amount of exercise, but over different periods of time either short and intense workouts, or long and slow workouts. Research suggests body fat is reduced by similar amounts between high- and low-intensity exercise, but higher intensities improved overall fitness and blood pressure, suggesting greater long-term health benefits.

Both long, slow endurance training (such as walking and running) and HIIT have been found to improve aerobic fitness (heart and lung function) in healthy adults. Though HIIT typically leads to larger increases in aerobic fitness, both high- and low-intensity training can be beneficial to heart health. But because HIIT is so intense, research suggests leaving about three days between HIIT workouts to let your body recover.

People with bone and joint problems may not enjoy HIIT due to the heavy loading that it requires. And though HIIT is reasonably safe for people with heart problems, its worth knowing that heart attacks are five times more likely following a HIIT workout than other types of exercise in higher-risk cardiac patients. However, the benefits of any exercise often outweigh the risks, in both healthy people and those with health conditions.

For these reasons, LIIT claims to be one compromise that mixes elements of HIIT and traditional endurance training. The aim is to use interval training but reduce the intensity and lengthen active periods, making it easier for people looking to get in shape or keep active. While HIIT focuses on doing explosive, intense movements quickly with long recovery such as burpees, sprints or box-jumps until you feel you cant do any more a LIIT workout might also incorporate these moves, but would concentrate more on form than exhaustion, and with shorter gaps between exercises.

But is LIIT as effective as HIIT? If you simply replace a brief HIIT session with one of a lower intensity, then it probably wont be more effective, unless the session is longer in order to make up for the loss of intensity. Think of intensity and time as a trade-off. If you reduce the intensity of the exercise you perform, you must increase the duration that youre exercising to burn a similar amount of calories.

So if your usual HIIT session is 10-15 minutes, an equivalent LIIT session might need to be 30 minutes to be as effective and a continuous jogging session could be 60 minutes.

The amount of calories used during HIIT, LIIT or endurance workouts is roughly the same if you bear in mind this intensity-duration trade off. This has not only been shown in multiple studies, but also demonstrated by myself on live TV, where I showed 30 minutes of continuous cycling and a 90-second all-out cycle sprint used similar amounts of energy.

Endurance fitness is a great marker of health, and will improve with all these types of exercise but HIIT is more likely to improve muscle power. Because none of the above targets muscle strength and mass, if youre doing HIIT, LIIT or any other type of endurance training, consider adding some type of strength-based resistance training as well.

The most important takeaway is that getting enough exercise is important for overall health. The government advises adults of all abilities to do 150 minutes of continuous exercise a week or 75 minutes of intermittent-style exercise a week. When it comes to doing HIIT- or LIIT-based exercise, the choice is really yours. Try both, and even consider changing your routine up. Exercise is only effective when done consistently, so the activity you like most is probably the right exercise for you.

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Low-intensity interval training can be as effective as HIIT but only if you spend more time working out - Metro Newspaper UK

What does it take to receive a National Science Foundation CAREER award? – Nevada Today

The National Science Foundations Faculty Early Career Development (CAREER) Program sets the bar high. It is the NSFs most prestigious award in support of early-career faculty, described by the NSF as supporting those with the potential to serve as academic role models in research and education and to lead advances in the mission of their department or organization.

Feifei Fan, assistant professor in the College of Engineering; Heather Holmes, assistant professor in the College of Science; and Robert Renden, assistant professor in the School of Medicine are the latest University of Nevada, Reno faculty to receive CAREER awards, bringing the total number of University faculty to receive the award since 2013 to 20.

Holmes wildfire-smoke research through the Department of Physics Atmospheric Sciences Program has received support from NASA, NSF and NIH and has resulted in epidemiological advancements. Her CAREER proposal, supported by a $400,000 grant, seeks to improve forecasting of wildfire smoke by improving atmospheric modeling, especially for summer atmospheric mixing over mountainous areas.

Fans research through the Department of Mechanical Engineering is set against the backdrop of the growing and critical importance of rechargeable batteries. Her CAREER proposal, supported by a $500,000 grant, focuses on the complex electrochemical cycling of batteries and, through study of the mechanics and other physical and chemical processes in electrodes, seeks to improve energy density, power density and capacity retention.

Rendens neurological research through UNR Meds Department of Physiology and Cell Biology and the Universitys Neuroscience Institute explores how brain cells maintain the energy needed to communicate at contact sites, called synapses. The prevailing view is that mitochondria supply this energy, but Rendens research data suggests other mechanisms are at play. Understanding this will inform experiments to correct systems where mitochondrial function is impaired, such as in neurodegenerative disease and aging. A $1.1 million CAREER grant will support his work.

The CAREER proposals of Holmes, Fan and Renden are in line with advice that Jamie Voyles-Ensor, associate professor of biology and 2019 CAREER awardee, received from an NSF program manager and shared during a February 2020 panel session sponsored by Research & Innovation. It should be something that can be accomplished, yet is a stretch, Voyles-Ensor said Its a tricky line to define.

More than 30 faculty members gathered for the panel session, indicating growing campus interest in the CAREER program and awards. Joining Voyles-Ensor as panelists were 2019 CAREER awardees Matteo Aureli, associate professor of mechanical engineering, and Mohammed Ben-Idris, assistant professor electrical and biomedical engineering.

Aureli shared that he held off applying until he was at a place in his career where he was more confident of his research interest and had a body of work to substantiate it. As he said, Its about your career. You need to show a line that is different from the work of your mentor.

It has to be new, advised Ben-Idris. Come up with a unique research approach. Make the case in the first two pages.

Describe the work in a way that is widely understandable one that your grandmother will understand before describing it in a scientific way that your science colleagues will understand, said Voyles-Ensor. Your proposal will be reviewed by scientists, but from a range of fields and not necessarily familiar with your field.

Aureli also encouraged developing a thorough, thought-out budget. It shows you are serious and committed. It helped me get more specific and dialed in about the scope of my project, he said.

In addition to the panel session, efforts by Research & Innovation to encourage and support faculty to prepare for the CAREER award application process include proposal writing workshops, a suggested timeline and the opportunity for external review. In the months of April and May, potential applicants are encouraged to draft their full-project summary for external-review. By June 1, contact your colleges grant coordinator or, if your college doesnt have a grant coordinator, contact Proposal Capture Manager Carrie Busha or Proposal Editor Kate Dunkelberger to develop a personalized timeline for submission.

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What does it take to receive a National Science Foundation CAREER award? - Nevada Today

Unlocking the Secrets of Brown Fat – Michigan Medicine

In recent years, brown fat has garnered attention as the so-called good fat that can protect against obesity and its associated health risks, like cardiovascular disease and diabetes. Two separate major studies, one led by Liangyou Rui, Ph.D. and one by Ling Qi, Ph.D., both with the department of molecular & integrative physiology, help explain brown fats properties.

Located in small pockets throughout the body, most mammals use brown fat (and its closely related cousin beige fat) to stay warm. In mice and humans, if you have more brown or beige fat, you are more protected from metabolic disease, says Rui, the Louis G. D'Alecy Collegiate Professor of physiology at U-M Medical School, whose lab studies the molecular and physiological mechanisms of obesity, diabetes and fatty liver disease. In a new study published in Nature Communications, Rui, first author Lin Jiang, Ph.D., and their colleagues reveal a pathway by which the hormone leptin contributes to weight loss.

Leptin regulates body weight by controlling appetite and energy expenditure, but exactly how has been a mystery. What is known, says Rui, is that leptin activates brown and beige fat. The new study elucidates a molecular accelerator of leptin action in the brain called Sh2b1. His team has found that Sh2b1 in the hypothalamus, an important brain region controlling body temperature and hunger among other functions, promotes the stimulation of the sympathetic nervous system. The sympathetic nervous system sends signals to brown and beige fat to activate it, thus maintaining body weight and metabolism.

The team demonstrated this proof-of-principle by creating two mouse models. Mice that lacked the Sh2b1 gene in the leptin receptor neurons had an incredibly reduced sympathetic drive to the brown and beige fat and reduced capability to promote energy expenditure, says Rui. This reduced the ability of brown fat to be metabolized into heat, lowering the mices core body temperature. Whats more, the mice also developed obesity, insulin resistance and a fatty liver. In contrast, mice with extra expression of Sh2b1 in their brains were protected from obesity.

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No one knew that Sh2b1 in the brain controls the sympathetic nervous system or was required for leptin to activate brown fat to increase energy expenditure, notes Rui. As for how this finding could be applied to humans, he says the hope is to eventually find a way to increase expression of Sh2b1 or its ability to enhance leptin signaling and fat burning.

Other U-M authors contributing to this paper include: Haoran Su, Xiaoyin Wu, Hong Shen, Min-Hyun Kim, Yuan Li, Martin G. Myers Jr, and Chung Owyang.

Brown fat gets its color from high amounts of iron-containing mitochondria, unlike the standard white fat linked to obesity. A team led by Qi, a professor of molecular & integrative physiology and internal medicine at U-M Medical School has been studying how mitochondria, the power plant of the cell, and another cellular structure called the endoplasmic reticulum (ER), which is involved in the production of proteins and lipids, interact inside brown fat cells.

In particular, theyve studied the role of a protein complex involved in a process called ER-associated protein degradation, or ERAD. Simply put, ERAD is the process of removing and destroying misfolded proteins, like taking out the trash out of the ER.

Everyone thought that ERAD was just part of the general cellular response when cells are undergoing ER stress, says Qi. Weve shown over the past six years that it plays a fundamental role in health and disease.

In a new study, published in Science, Qi along with first authors Zhangsen Zhou, Ph.D., Mauricio Torres, Ph.D., and their colleagues demonstrate how an ERAD protein complex affects the proper function of mitochondria.

Typically, the ER and mitochondria have ongoing interaction at touch points called mitochondria-associated membranes. These points of contact mark areas for mitochondria to divide for the production of new mitochondria and for the exchange of other molecules such as lipids and calcium. The ER forms tubules that surround the mitochondria to get them ready for division.

Using state of the art 3D imaging, the researchers discovered what happens to mitochondria in brown fat that are missing part of an ERAD protein complex, called Sel1L-Hrd1, when exposed to cold.

When you delete this complex in brown adipocytes, the mitochondria become elongated and enlarged, says Qi. The 3D image enabled them to view a previously unrecognized interaction between the mitochondria and the ER, with the mitochondria wrapping in a U-shape around the ER tubules.

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When the mice were placed in a cold environment, the ends of the outer membrane of the mitochondria folded back on itself, eventually fusing and completely enveloping the ER tubules. The result, says Qi, are abnormally large, misshapen, dysfunctional mitochondria.

We showed that these mitochondria dont function normally and the mice become cold sensitive, their body temperature dropping very quickly, says Qi. In other words, without this ERAD protein complex, the brown fat is not being used to generate heat. Under a microscope, this dysfunctional brown fat had larger droplets of lipids than brown fat from mice with the protein complex intact.

This is highly unexpected. The results here fundamentally change our understanding of ER-mitochondrial communication and further demonstrate the importance of an ER degradation complex in cell biology.

This paper also includes contributions from the following U-M authors: Christopher Halbrook, Franoise Van den Bergh, Rachel B. Reinert, Siwen Wang, Yingying Luo, Allen H. Hunter, Thomas H. Sanderson, Aaron Taylor, Costas A. Lyssiotis, Jun Wu and Daniel A. Beard.

Papers cited:

Leptin receptor-expressing neuron Sh2b1 supports sympathetic nervous system and protects against obesity and metabolic disease, Nature Communications, DOI: 10.1038/s41467-020-15328-3

Endoplasmic reticulumassociated degradation regulates mitochondrial dynamics in brown adipocytes, Science, DOI: 10.1126/science.aay2494

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Unlocking the Secrets of Brown Fat - Michigan Medicine

Stress Theory in Nursing – CNBCAfrica.com

The relationships between the development of coping expertise, well being, and resilience in nursing are examined.

In basic, you can find four elements to a persons physiology that play a role in their ability to cope and adapt in numerous circumstances. The very first element is resilience, which is defined as an individuals ability to cope with life adversity and obtain emotional balance.

Resilience may be created via many processes which includes optimistic thinking, social assistance, robust relationships, and sense of meaning. Its the foundation for health-related education.

Adaptability, on the other hand, is definitely the capacity to alter with new info, and to adopt alterations because the predicament adjustments. Adaptability might be seen because the capability to focus on studying within a changing environment. This is vital for nurses who must remain up-to-date on changing trends in healthcare practices and interventions.

Adaptation and Resilience will be the big concepts inside the use in the Adaptation Model and Strain Theory in Nursing Expertise. This tool helps nurses to turn out to be far more powerful, empathetic, and compassionate.

The second concept is Personal Strength, which addresses the patients perceived capability to cope with their illness and the nurses role in help. It can be this feeling of strength that tends to make a difference involving the best outcomes and poor outcomes. The strength of someone is what college homework helper tends to make them superior in a position to handle stressors and outcomes inside a higher high-quality of care.

Adapting and coping can each happen with little or no pressure. An adaptive response takes spot when there is a transform in the situation from the person, plus a coping response occurs when there is a modify in the atmosphere. When the anxiety is one-sided, it is actually called Situational Stress and happens when an individual feels that there is absolutely nothing that can be accomplished.

The third idea in the Tension Theory is Social Help. The emotional and cognitive benefits of being surrounded by individuals who have an understanding of and help their feelings and behaviors give a fantastic atmosphere in which to flourish.

Another crucial notion in the Adaptation Model and Tension Theory in Nursing Abilities is that there is no one particular size fits all approach to treating the illnesses and injuries that occur in our everyday lives. Which is why there is a need for nurses to be versatile, caring, and caring so that you can cater towards the desires of every patient. This is a crucial skill, as we cant place a bow on anything that occurs.

The Health Care Nurses carries out the every day activities of caring for patients, but they also study, create, and educate themselves as a way to improved care for patients. This can be how they make a difference inside the lives of other individuals. They cant assistance but discover about various illnesses and situations and how they affect people today.

These are just a number of the lots of valuable and relevant concepts that may be discovered by nursing students and faculty so as to make their work less complicated. It is also vital for them to come into https://english.yale.edu/courses/medieval-literature-movies the program armed with a superior working know-how of those concepts so that they are able to apply what they have discovered essaycompany com to their practice around the job.

The thought that you will discover no single principles to life and that there are normally several relevant ideas that a nurse need to know is very critical inside the stress theory in nursing theories and empirical practice. Nursing is usually a science, plus a nurses function in society will be to care for other folks, generating a difference in their lives.

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SPANX-A/D protein subfamily plays a key role in nuclear organisation, metabolism and flagellar motility of human spermatozoa. – Physician’s Weekly

Human sperm protein associated with the nucleus on the X chromosome (SPANX) genes encode a protein family (SPANX-A, -B, -C and -D), whose expression is limited to the testis and spermatozoa in normal tissues and to a wide variety of tumour cells. Present only in hominids, SPANX-A/D is exclusively expressed in post-meiotic spermatids and mature spermatozoa. However, the biological role of the protein family in human spermatozoa is largely unknown. Combining proteomics and molecular approaches, the present work describes the presence of all isoforms of SPANX-A/D in human spermatozoa and novel phosphorylation sites of this protein family. In addition, we identify 307 potential SPANX-A/D interactors related to nuclear envelop, chromatin organisation, metabolism and cilia movement. Specifically, SPANX-A/D interacts with fumarate hydratase and colocalises with both fumarate hydratase and Tektin 1 proteins, involved in meeting energy demands for sperm motility, and with nuclear pore complex nucleoporins. We provide insights into the molecular features of sperm physiology describing for the first time a multifunctional role of SPANX-A/D protein family in nuclear envelope, sperm movement and metabolism, considered key functions for human spermatozoa. SPANX-A/D family members, therefore, might be promising targets for sperm fertility management.

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SPANX-A/D protein subfamily plays a key role in nuclear organisation, metabolism and flagellar motility of human spermatozoa. - Physician's Weekly

Hearing from Huskies: What you miss about UConn – UConn Daily Campus

Some people, like Andrew Mora said on Instagram, miss good ol Homer Babbidge (hopefully not the stress that often accompanies library sessions), while others talked about classic UConn features that we love to hate.

Instagram user @thezajac responded to the prompt with The wind that blows both ways, while @eric.sturt said The wind knocking me over. @marausha13 said Walking over a mile to get to my class, referring to the rather large size of campus that always helps us accomplish our step limit.

I missed when you walked outside and it decided to start misting even though the weather app said it wasnt going to rain, Berry said.

I miss the terrible wi-fi, Sruthi Takillapati, a fourth-semester physiology and neurobiology major, said, reminding us all of the divide between networks UConn Secure and UConn Guest, but also acknowledging whats really important: I miss seeing all the doggies!

Sofia Rodriguez, a fourth-semester women, gender and sexuality studies major, made sure to acknowledge everyones favorite dog, commenting with Jonathan the Huskys Instagram handle on our Instagram post.

Huskies made sure not to forget UConns successful sports teams. On Instagram, @moirajude said March Madness, while on Facebook, Arica Nicole commented, UConn womens basketball.

Unsurprisingly, many students and other members of the communities mentioned missing the people that made UConn home, with Madison Busick commenting on Facebook about student organizations.

I miss the lunch dates with my friend group at the U, Paula Norato said on Facebook, while Sarah Fletcher similarly commented, I miss running into my friends while walking around on campus and having random conversations.

Kaylee Grace, a fourth-semester physics and women, gender and sexualities studies double major, said, Having communities to turn to for support, in person, whenever I need it, while Instagram user @rigel.wachtmann said, Running into people I know on campus spontaneously. UConn English professor Rebecca Rumbo commented Being in the classroom with my students. Marisa Liliana commented about missing the people and the commotion.

I miss being able to walk around campus and never know which friend you might run into, and the random chances to catch up with them and meet strangers, Stephanie Reitz, university spokesperson, commented on Facebook.

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Hearing from Huskies: What you miss about UConn - UConn Daily Campus

Kitzman Receives National Award for Outstanding Advocacy in Neurologic Therapy – UKNow

LEXINGTON, Ky. (March 31, 2020) Patrick Kitzman, associate dean for research in the University of Kentucky College of Health Sciences, received the Outstanding Advocacy in Neurologic Physical Therapy Award from the American Physical Therapy Association (APTA) at their annual conference last month. This prestigious honor is given to those in the field of physical therapy who have made an extraordinary impact on advocacy for neurologic physical therapy.

Kitzman has committed his career to advocacy and selfless service through his work in physical therapy and with the Kentucky Appalachian Rural Rehabilitation Network (KARRN), which he established in 2008.KARRNs collaborative team, spanning across Kentucky, has touched countless lives in their mission to empower communities impacted by disability.

I cant advocate for someone unless Im working with them. Its presumptuous to say, I know what you need, Kitzman said. The moment we at KARRN start working with someone, we agree to be their advocate and do whatever it takes to find resources for them.

Tony English, chair of the department of physical therapy, praised Kitzmans dedication to bringing life-changing physical therapy to underserved populations.

KARRN has established a network of resources, multiple educational materials, a team of experts in the many disciplines that deal with spinal cord injury, stroke, and brain injury, and centralized these in one location, he said. They ensure that after injury and formal rehabilitation people can return to their homes with confidence and the necessary resources to function at the highest possible level.

Kitzmans calling to serve others extends across UKs campus and beyond as shown by the many partnerships and interdisciplinary collaborations he has fostered over the years.

Under Dr. Kitzmans patience and guidance, KARRN has directly influenced the successes of the Kentucky Congress on Spinal Cord Injury (KCSCI) throughout our six years of existence, said Alexander G. Rabchevsky, professor of physiology and endowed chair at the UK College of Medicine. His efforts have united individuals with spinal cord injuries in the greater Lexington area and beyond to bring legislative changes. Virtually all of the programs that the KCSCI undertakes are sponsored by KARRN, and the combined registries have expanded the community outreach to help those living with disabilities in underserved regions of the Commonwealth.

One of Kitzmans more recent initiatives is Project CARAT (Coordinating and Assisting the Reuse of Assistive Technology). This project is in collaboration with the Doctor of Physical Therapy program at the UK College of Health Sciences and allows students to experience hands-on education by refurbishing assistive technology and redistributing items to underserved individuals.

Dr. Kitzman is passionate about advancing the neurologic therapy field and improving the quality of life for individuals living with neurologic impairments, said Frances J. Feltner, director of the UK Center of Excellence in Rural Health, which houses manyKARRNinitiatives. His consistency in engaging students and contributions to the profession are truly remarkable.

Dedication to research, advocacy, and delivery of compassionate care are all hallmarks of Kitzmans character. And, its these traits hes passing on to every student who comes across his path.

When I first started UK, it had been years since I had sat in a research methods class. I wasnt even sure if I was really qualified to be there, said Kathleen Sutton, one of Kitzmans former students. Pat reassured me time and again that research is about knowing how to ask a question, and the confidence I now have in myself as a researcher is a direct reflection of his mentorship. I know that when I graduate, I can be an effective agent of change in whatever community I work in because of the time Ive spent learning in his lab.

When asked about receiving such a distinguished award, Kitzman is quick to recognize others for their support of his career.

I am humbled to receive this award. But, when you do advocacy work, its a group effort, he said. It takes all of us to make a change. Its my pleasure to represent all the wonderful people I work with. This award encompasses the core of what my entire team does every day.

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Kitzman Receives National Award for Outstanding Advocacy in Neurologic Therapy - UKNow

D.I.Y. Coronavirus Solutions Are Gaining Steam – The New York Times

Mr. Oliver reached out to local distillers to follow Oregons lead and join forces. In the past week, several have stepped up, including OOLA Distillery, which quickly collected all the raw materials, from alcohol to storage bottles. The distillery is ramping up to churn out thousands and thousands of liters of bottles as early as next week, said Kirby Kallas-Lewis, the founder of OOLA. It will distribute the sanitizer to emergency medical workers, hospital staff and local community members; it also plans to sell it both to individuals and various businesses.

The need is now, Mr. Kallas-Lewis said.

Trevor Smale, an illustrator in Toronto, posted an early illustration of his ventilator design to the Facebook group. The responses prompted him to set up a GitHub page for his project, which he called OpenLung. He is now working with OpenSource Ventilator Ireland, a volunteer organization focused on developing low-cost and open-source ventilators.

Colin Keogh, a co-founder of OpenSource Ventilator Ireland, said that as thrilling as this challenge has been from an engineering and innovation standpoint, he hoped that hospitals would never have to use the equipment they were developing.

Its seen as an emergency intervention, he said. We hope well be able to cope.

Outside of the Facebook group, others are organizing efforts to find open-source solutions to the shortage. In Boston, a team of anesthesiology residents at Massachusetts General Hospital grew concerned that it might only be a matter of time before the United States ran out of ventilator machines.

Together, the residents founded the CoVent-19 Challenge, a virtual global contest to increase the capacity of hospitals to provide mechanical ventilation.

We want people to come with great ideas, and we want to provide them the support that they need to develop something that is compatible with the physiology of the human body, said Diana Barragan-Bradford, co-director of the challenge.

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D.I.Y. Coronavirus Solutions Are Gaining Steam - The New York Times

The Chronicle of the Horse – The Chronicle of the Horse

In the Chronicles new series, we follow various equine professionalsthroughout a typical day. In this installment, Jennifer Gates took us through her day on March 12, prior to the mass cancellation of equestrian events.

Gates started riding at a young age and moved up the hunter/jumper ranks as a junior. She competed at the Adequan FEI North American Junior and Young Rider Championships three times, earning team gold and silver and an individual bronze medal. In 2017 she piloted Alex to the $30,000 USEF Under-25 National Championship at the National Horse Show (Kentucky). She graduated from Stanford University (California) in 2018 and took a year to pursue riding before starting medical school at Icahn School of Medicine at Mount Sinai (New York).

March 12, 2020: With the precautions being taken nationwide around the coronavirus, I am studying remotely from Florida, and all of my medical school classes have temporarily been moved online. Between studying and going to class from home and having family in town for the weekend, it ended up being a busier day than normal. I try to incorporate some days with fewer planned activities and time to rest as well, but this day was particularly packed with fun and exciting things.

8:30 a.m. Wake up! I generally start my morning with some meditation or breathing exercises after some cuddling with Earl before getting ready for the day.

10 11:30 a.m. Rode Alex and twinned with Adrienne Sternlicht, one of my closest friends! Then rode [Pumped Up Kicks], who loves to go up on the hill and look around the farm. I also listened to The Daily podcast on the latest coronavirus news.

11:30 12 p.m. Did a Peloton workout, something I have really been enjoying lately!

12 4 p.m. Lunch, then a few hours of study time and online classes. 4:30-5:30 p.m. Pilatesone of my favorite exercise routines that I feel has helped so much with riding. Since Ive been studying from home, and all of my classes are online, I have found incorporating fitness breaks throughout my day to be extremely beneficial!

I dont generally work out twice a day unless I feel particularly inspired or want to take a break from studying. Its all about balance and finding activities that you enjoy doing. 5:30 6 p.m. Had a call with mental coach Peter Crone, on my way home from Pilates. I have been working with Peter for the past two years, and he has been instrumental in my mindset both in the competition ring and in life in general. Mental health and mindset are both super important to me, and I encourage everyone to learn more about yourself and prioritize this. I also meditate and journal regularlythese practices help me to center myself when I experience anxiety.

I have been fortunate to work with various practitioners over the course of my life and have learned that mental health is paramount to success in whatever you are pursuing.

6 8 p.m. Had dinner with my fiance Nayel Nassar and his mom, Iman, and then we went for a walk!

8 10 p.m. More studying! This time, I had a video conference with a friend to study pulmonary physiology.

10 p.m. 12 a.m. Since in-person classes have been canceled, I caught up on watching (and synthesizing) lectures on renal physiology before getting ready for bed! I try to take some time to catch up on the day and review study notes at the end of the day.

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The Chronicle of the Horse - The Chronicle of the Horse