Category Archives: Neuroscience

Kentucky Neuroscience Institute Home – UK HealthCare

The Kentucky Neuroscience Institute (KNI) integrates the expertise of the University of Kentuckys neurology and neurosurgery clinicians and researchers. KNI is a referral center dedicated to providing comprehensive care to our patients with the most complex neurological conditions.

Neurosurgeons and neurologists at KNI diagnose and treat a wide spectrum of neurological conditions involving the brain, spine, nerves and muscles. Our team includes neurosurgeons, neurologists, neuropsychologists, therapists, nurses and other clinicians who use the most advanced surgical and medical treatments for brain, spinal cord, and nerve and muscle diseases and disorders. UK faculty also conduct cutting-edge clinical research and can offer innovative new treatment approaches. Our faculty are also training the next generation of health care providers and investigators. KNI is on the leading edge of patient care, research and education and puts the power of advanced medicine and an entire team of specialists to work on your condition.

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BMC Neuroscience Archives – Retraction Watch at Retraction Watch – Retraction Watch (blog)

Stanley Rapoport. Source: NIH

Neuroscientist Stanley Rapoportjust cant catch a break.

Rapoport, whos based at National Institute on Aging, is continuing to experience fallout from his research collaborations, after multiple co-authors have been found to have committed misconduct.

Most recently,Rapoport has hadfour papers retracted in three journals, citingfalsified data in a range of figures. Although the notices do not specify how the data falsification occurred,Jagadeesh Rao, who was recentlyfound guilty of research misconduct,iscorresponding author on all four papers.

Back in December, Rapoport told usthat a number of retractions [for] Rao are still in the works: Read the rest of this entry

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BMC Neuroscience Archives - Retraction Watch at Retraction Watch - Retraction Watch (blog)

Neuroscience says listening to this song reduces anxiety by up to 65 percent – AOL

Everyone knows they need to manage their stress. When things get difficult at work, school, or in your personal life, you can use as many tips, tricks, and techniques as you can get to calm your nerves.

So here's a science-backed one: make a playlist of the 10 songs found to be the most relaxing on earth.

Sound therapies have long been popular as a way of relaxing and restoring one's health. For centuries, indigenous cultures have used music to enhance well-being and improve health conditions.

Now, neuroscientists out of the UK have specified which tunes give you the most bang for your musical buck.

INC. TODAY'S MUST READS: Be the Most Persuasive Person in the Room: 9 Things Highly Influential People Always Do, According to Science

The study was conducted on participants who attempted to solve difficult puzzles as quickly as possible while connected to sensors. The puzzles induced a certain level of stress, and participants listened to different songs while researchers measured brain activity as well as physiological states that included heart rate, blood pressure, and rate of breathing.

According to Dr. David Lewis-Hodgson of Mindlab International, which conducted the research, the top song produced a greater state of relaxation than any other music tested to date.

In fact, listening to that one song -- "Weightless" -- resulted in a striking 65 percent reduction in participants' overall anxiety, and a 35 percent reduction in their usual physiological resting rates.

That is remarkable.

Equally remarkable is the fact the song was actually constructed to do so. The group that created "Weightless", Marconi Union, did so in collaboration with sound therapists. Its carefully arranged harmonies, rhythms, and bass lines help slow a listener's heart rate, reduce blood pressure and lower levels of the stress hormone cortisol.

When it comes to lowering anxiety, the stakes couldn't be higher. Stress either exacerbates or increases the risk of health issues like heart disease, obesity, depression, gastrointestinal problems, asthma, and more. More troubling still, a recent paper out of Harvard and Stanford found health issues from job stress alone cause more deaths than diabetes, Alzheimer's, or influenza.

In this age of constant bombardment, the science is clear: if you want your mind and body to last, you've got to prioritize giving them a rest. Music is an easy way to take some of the pressure off of all the pings, dings, apps, tags, texts, emails, appointments, meetings, and deadlines that can easily spike your stress level and leave you feeling drained and anxious.

Of the top track, Dr. David Lewis-Hodgson said, "'Weightless' was so effective, many women became drowsy and I would advise against driving while listening to the song because it could be dangerous."

So don't drive while listening to these, but do take advantage of them:

10. "We Can Fly," by Rue du Soleil (Caf Del Mar)

9. "Canzonetta Sull'aria," by Mozart

8. "Someone Like You," by Adele

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7. "Pure Shores," by All Saints

6. "Please Don't Go," by Barcelona

5. "Strawberry Swing," by Coldplay

4. "Watermark," by Enya

3. "Mellomaniac (Chill Out Mix)," by DJ Shah

2. "Electra," by Airstream

1. "Weightless," by Marconi Union

I made a public playlist of all of them on Spotify that runs about 50 minutes (it's also downloadable).

INC. TODAY'S MUST READS: All Extremely Confident People Give Up These 13 Habits

There's also a free 10-hour version of "Weightless" available if you want a longer listening experience.

RELATED: The most stressful jobs in America

11 PHOTOS

The most stressful jobs in America

See Gallery

Broadcaster

Stress score: 47.93

(mediaphotos via Getty Images)

Taxi driver

Stress score: 48.18

Public relations executive

Stress score: 48.50

(Hero Images via Getty Images)

Corporate executive (senior)

Stress score: 48.56

(Chris Ryan via Getty Images)

Newspaper reporter

Stress score: 49.90

(mediaphotos via Getty Images)

Event coordinator

Stress score: 51.15

(Jupiter Images)

Police officer

Stress score: 51.68

(Juanmonino via Getty Images)

Airline pilot

Stress score: 60.54

(MatusDuda via Getty Images)

Firefighter

Stress score: 72.64

(stevecoleimages via Getty Images)

Enlisted military

Stress score: 72.74

(MivPiv via Getty Images)

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Neuroscience says listening to this song reduces anxiety by up to 65 percent - AOL

Department of Psychiatry & Behavioral Neuroscience – Henry …

National Institutes of Health - Bethesda, MD (Neuroscience)

Board Certifications American Board of Psychiatry and Neurology (General Psychiatry),

American Board of Psychiatry and Neurology (Geriatric Psychiatry)

The Ohio Psychiatric Physicians Foundation, President 2008-2010

American College of Neuropsychopharmacology, Fellow

Society of Biological Psychiatry

American Academy of Clinical Psychiatrists, President 1989-1990

The American Board of Psychiatry and Neurology, Senior Examiner

Cincinnati Psychiatric Society, President 2007-2009

International College of Neuropsychopharmacology

American Psychiatric Association, Distinguished Life Fellow

National Alliance on Mental Illness

American College of Psychiatrists, Fellow

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Department of Psychiatry & Behavioral Neuroscience - Henry ...

Neuroscience Center Pioneering Alzheimer’s, Dementia Treatments – CBS Minnesota / WCCO

May 31, 2017 11:07 PM By Liz Collin

MINNEAPOLIS (WCCO) One of the few places in the country developing new treatments for dementia and Alzheimers disease is in the Twin Cities.

And those researchers and doctors now work under one roof for the first time.

HealthPartners opened the doors to its new Neuroscience Center in St. Paul this spring.

Every detail was designed with the patient in mind.

WCCO has followed one of those patients for more than two years. Dr. Paul Quinn is in the early stages of Alzheimers disease.

Paul and Peg Quinn (credit: CBS)

He always comes across somewhat hopeful in his assessment of his condition.

I cant notice a significant difference, Paul Quinn said.

He been confronting whats called mild cognitive impairment (MCI) for the last three years.

Quinn and his wife, Peg, will soon learn the results of his annual cognitive review. They are seeing if his diagnosis has changed; if his memory disorder has fully developed into Alzheimers disease.

That news will be delivered to the Quinns for the first time inside a one-of-a-kind medical center in the Midwest, which is expected to serve 50,000 patients a year.

The $75-million, 130,000-square-feet center focuses solely on brain and spine conditions.

There are finishes to help dementia patients feel more comfortable, like large exam rooms and an open floor plan.

Locations are marked with something other than numbers, which can be hard for patients to recall.

They suggested we have two ways of remembering, so we did a color and a letter at each neighborhood, said Business Systems Supervisor Heather Engebretson.

But the biggest breakthroughs happen in the basement, where Senior Research Director William Frey is on the front lines of testing medicine.

Here we are testing a number of treatments for brain disorders, Dr. Frey said.

(credit: CBS)

One of the potential treatments is a nasal spray that injects insulin into the brain.

The things we discover here, like our nasal insulin treatment that improves memory in people with Alzheimers, is actually in human clinical trials on the third floor of this very building, Dr. Frey said.

Quinn is part of another clinical trial developed by the same team that involves taking a pill a day.

It is part of a routine that, for the most part, he still keeps up himself.

Every day we wake up and were both still there and we just keep on keeping on, Peg Quinn said.

She has noticed a significant change in her 78-year-old husband since his diagnosis. Details in stories from the past now have slight changes, like when we ask Paul about the time he met Peg in 1961.

Then this gal comes in shes got a green, stylish rain coat and she has a hat on, too, he said.

His wife says she had never heard those details before.

Subtle changes to Pauls long-term memory worry his family since his short-term memory is barely there, even when it comes to relatives names.

Half the patients with MCI develop Alzheimers disease or another form of dementia within five years of the diagnosis.

Dr. Michael Rosenbloom tells Paul that his function is good overall, since hes still able to do things like cook and drive.

You were having problems naming things, but it wasnt enough to shift things dramatically, Dr. Rosenbloom said. I think youre more or less stable with a little bit worsening. I would still call this mild cognitive impairment based on what youre telling me. I think this is not a bad result. If I were in your shoes, Id be happy to hear this.

Dr. Rosenbloom says it is those functions that determines whether or not patients like Paul have MCI or Alzheimers.

It is the question that keeps the Quinns planning for the future, yet focused on living each day.

Keep on keeping on as long as you can, Peg Quinn said.

Dr. Rosenbloom did recommend that Paul and others with memory problems use brain-training game. Many can be found online.

He also says exercise is extremely important. Studies have shown even a half hour of aerobic activity, three times a week, can be as effective as medication in some patients.

At 15 years old, Liz Collin made her broadcast debut covering a tornado that touched down in southwest Minnesota. It was her first night on the job at KWOA and KO95. Since those radio days in her hometown of Worthington, Minnesota, she's held...

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Neuroscience Center Pioneering Alzheimer's, Dementia Treatments - CBS Minnesota / WCCO

Performance of Eli Lilly’s Neuroscience Products in 1Q17 – Market Realist

What Drives Eli Lilly's Valuation after Its 1Q17 Earnings? PART 8 OF 9

Eli Lilly & Co.s (LLY) neuroscience products portfolio includes the drugs Cymbalta, Strattera, and Zyprexa.The chart below shows revenues for its three key neuroscience productsCymbalta, Strattera, and Zyprexasince 1Q15.

Cymbalta, an antidepressant, reported a 12% decline in its 1Q17 revenues to $174.6 million, compared to ~$198.7 million in 1Q16. The drug reported lower sales outside the US markets, specifically Europe and Canada, due to the loss of exclusivity

Cymbalta reported a 20% decline in revenues to $140.5 million from international markets, partially offset by 46% growth in the US market to $34.1 million.

Strattera, a drug for the treatment ofattention-deficit hyperactivity disorder (or ADHD), reported 4% growth in its 1Q17 revenues to $196.2 million, compared to $188.1 million for 1Q16. This growth was driven by strong performance in its US and international markets.

Zyprexa, an antipsychotic drug, reported a 31% decline in revenues to $147.5 million in 1Q17, compared to $212.8 million in 1Q16. The decline was due to the exposure to generic competition in theUS and its international markets.

For broad-based exposure to the industry, investors can consider the Vanguard Healthcare ETF (VHT), which holds 2.4% of its total assets in Eli Lilly. VHT also holds 10.0% of its total assets in Johnson & Johnson (JNJ), 2.9% of its total assets in Celgene (CELG), 2.2% of its total assets in Abbott Laboratories (ABT), and 1.7% of its total assets in Biogen (BIIB).

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Performance of Eli Lilly's Neuroscience Products in 1Q17 - Market Realist

Do dads treat daughters better than sons? Emory study finds striking differences in treatment of children – Atlanta Journal Constitution

New researchfrom Emory University scientists finds that fathers may play favorites when it comes to their children.

The study, published inthe American Psychological Associations journal Behavioral Neuroscience last week, examined the influence of fathers brain responses to male or female children.

Researchers from Emory University and the University of Arizona gathered data from 52 fathers of toddlers (30 daughters, 22 sons) in the Atlanta area for the study.

The fathers wore small computers on their belts for one weekday and one day on the weekend. The gadget recorded any sounds in 50-second intervals every nine minutes during the 48-hour period as well as nighttime interactions in the childs room, where the device was left charging.

The men also underwent MRI brain scans as they viewed photos of unknown adults, unknown children and their own child with neutral, happy and sad facial expressions.

A father and daughter walk in the city center on July 17, 2012 in Berlin, Germany. Sean Gallup/Getty Images

The fact that fathers may actually be less attentive to the emotional needs of boys, perhaps despite their best intentions, is important to recognize, lead researcher Jennifer Mascaro said.

In addition, regarding the finding that dads with daughters tend to use more body-related words, researchers noted that previous research has shown pre-adolescent girls are more likely than boys to report low self-esteem and body image issues.

But some scientists, includingAlan Kazdin, child psychiatry professor and director of Yale Parenting Center, warned against jumping to any conclusions in the small sample study.

Daughters and sons are very different even in utero and then when they're infants they start behaving very differently,Kazdin told CBS News. Interactions between parents and children drive and influence each other's brains. So what we don't know here is whether the fathers drive the behaviors of their daughters and the sons or if the daughters and the sons drive the behavior of the fathers.

In addition, because the research was conducted in the U.S., cultures with varying societal norms are not as well represented.

But knowing there may be unintentional biases in the treatment of children based on gender could help future researchers explore the subject and possibly help fathers identify their biases, Kazdin said.

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Do dads treat daughters better than sons? Emory study finds striking differences in treatment of children - Atlanta Journal Constitution

Investigation: 4 Swedish Neuroscience Institute surgeons double-booked more than half of their cases between 2014 … – Becker’s Orthopedic &…

Seattle-based Swedish Health has frequently double-booked spine surgeries at its Cherry Hill campus, The Seattle Times reports.

Here are five insights:

1. The Seattle Times reporters obtained internal surgery data that revealed some Swedish brain and spine surgeons "routinely ran multiple operating rooms at the same time while keeping patients in the dark about the practice." The reporters also came to this conclusion based on patient and medical staff interviews.

2. From 2014 to 2016, four Swedish Neuroscience Institute surgeons oversaw multiple ORs concurrently for more than half of their cases. The surgeons routinely performing concurrent surgeries in this time frame included Rod Oskouian, MD; Johnny Delashaw, MD; Jens Chapman, MD; and David Newell, MD.

3. Guy Hudson, MD, Swedish's interim CEO, labeled these surgeries as "overlapping," indicating a second surgery simply begins with the close of the previous one. The Seattle Times reports Dr. Hudson previously said surgeons are not allowed to schedule cases with the same start time. Despite this claim, The Seattle Times found more than 200 times when surgeons started two cases at the same time or within a five-minute lapse between 2014 and 2016. The reporters discovered these cases often overlapped for more than one hour.

4. Swedish is not alone in allowing overlapping surgeries, as the topic has come under fire in recent years. Dr. Hudson pointed to metrics that the Cherry Hill facility demonstrated better overall outcomes compared to the industry benchmark. He noted that they are still looking into outcomes comparisons between overlapping and non-overlapping cases.

5. In May, Swedish Cherry Hill began giving consent forms to patients outlining the possibility of overlapping surgeries. Patients read that their surgeon "will be assisted by a care team," The Seattle Times reports, but the form does not spell out that physicians-in-training may be performing some of the surgery without surgeon supervision.

6. Swedish has faced investigations since The Seattle Times published a report on the Swedish Neuroscience Institute on the Cherry Hill campus in February. Former Swedish CEO Anthony Armada resigned in February after the report prompted state regulators to investigate. Dr. Delashaw also resigned from his post as chair of the Swedish Neuroscience Institute on the Cherry Hill campus on March 1, amid a state health regulatory investigation into complaints filed against him.

Find out more about The Seattle Times investigation, here.

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Investigation: 4 Swedish Neuroscience Institute surgeons double-booked more than half of their cases between 2014 ... - Becker's Orthopedic &...

Vision Keeps Maturing until 30s – Early 40s, Study Finds – Sci-News.com

The human primary visual cortex the brains vision-processing center that was previously thought to mature within the first few years of life actually continues to develop until sometime in the 30s or early 40s, a new study has found.

According to Siu et al, vision keeps maturing until mid-life. Image credit: Pexels.

Lead author Kathryn Murphy, a professor in the Department of Psychology, Neuroscience and Behavior at McMaster University, and co-authors obtained post-mortem brain-tissue samples from 30 people ranging in age from 20 days to 80 years to study how expression of a set of glutamatergic proteins (PSD-95, GluA2, GluN1, GluN2A, GluN2B) which regulate neurotransmission at a majority of synapses in the human visual cortex changes in this region over time.

Their analysis recasts previous understanding of when this part of the brain reaches maturity, extending the timeline until about age 36, plus or minus 4.5 years.

The finding was a surprise to the authors, who had expected to find that the cortex reached its mature stage by 5 to 6 years, consistent with previous results from animal samples and with prevailing scientific and medical belief.

Our results show development of the visual cortex occurs in five different stages that mirror changes in vision, the researchers said.

For example, the expression of three of these proteins GluN1, PSD-95 and GluA2 peaks between 5 and 11 years of age, which coincides with the end of the period when children are susceptible to developing amblyopia, or lazy eye.

Another protein, GluN2A, did not peak until about 40 years of age and then dropped dramatically, by about 75%, in adults over 55 years of age, perhaps signaling degeneration in the visual cortex.

Theres a big gap in our understanding of how our brains function, Prof. Murphy said.

Our idea of sensory areas developing in childhood and then being static is part of the challenge. Its not correct.

Treatment for conditions such as amblyopia, for example, have been based on the idea that only children could benefit from corrective therapies, since it was thought that treating young adults would be pointless because they had passed the age when their brains could respond, Prof. Murphy added.

Though the research is isolated to the visual cortex, it suggests that other areas of the brain may also be much more plastic for much longer than previously thought.

This research was presented in a paper published in the Journal of Neuroscience on May 29, 2017.

_____

Caitlin R. Siu et al. Development of glutamatergic proteins in human visual cortex across the lifespan. Journal of Neuroscience, published online May 29, 2017; doi: 10.1523/JNEUROSCI.2304-16.2017

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Vision Keeps Maturing until 30s - Early 40s, Study Finds - Sci-News.com

IRF Report Details Recommendations for Translating the Neuroscience of Behavioral Economics into Employee … – Benzinga

The Incentive Research Foundation is pleased to release "Using Behavioral Economics Insights in Incentives, Rewards, and Recognition: The Neuroscience," an innovative application of scientific findings to employee motivation and rewards. Offering practical C-suite takeaways, the IRF's report describes the unifying behavioral economic principles connecting the powerful role of emotions with employee performance.

(PRWEB) May 30, 2017

The Incentive Research Foundation is pleased to release "Using Behavioral Economics Insights in Incentives, Rewards, and Recognition: The Neuroscience," an innovative application of scientific findings to employee motivation and rewards. Offering practical C-suite takeaways, the IRF's report describes the unifying behavioral economic principles connecting the powerful role of emotions with employee performance.

The report explains how behavioral economics can help employers better understand what motivates employees, because it recognizes the majority of human decision-making is emotional as opposed to rational. Behavioral economics integrates social, cognitive, and emotional factors to more fully explain human decision-making biases. Neuroeconomics provides an additional powerful layer of proof by exploring the biologic underpinnings of decision-making. Technological advances, such a brain-imaging technology, enable researchers to probe the brain in unprecedented detail and are powering an explosion in neuroeconomics research.

"From studies on oxytocin to dopamine to the pre-frontal cortex, there is no shortage of emerging neuroeconomics research on what makes humans tick," said Melissa Van Dyke, IRF President. "'Using Behavioral Economics Insights in Incentives, Rewards, and Recognition: The Neuroscience' curates and explains the research so that incentives, rewards, and recognition professionals can use this knowledge to better understand what motivates employees and ultimately create more engaging and productive work environments."

The most powerful neuroeconomics finding is that all forms of reward are processed in the brain's master reward center, the striatum, and are experienced as rewarding feelings. This means rewarding employees intrinsically by treating them better or rewarding them extrinsically with money, trips, or merchandise are treated equally in the brain. This important finding supports organizations shifting the emphasis in incentive programs to non-cash rewards to build more effective, fulfilling work environments. Other key takeaways include:

To download the full study, "Using Behavioral Economics Insights in Incentives, Rewards, and Recognition: The Neuroscience," and the accompanying white paper "Translating the Neuroscience of Behavioral Economics into Employee Engagement," please visit: http://theirf.org/research/translating-the-neuroscience-of-behavioral-economics-into-employee-engagement/2083/

To download the companion study, "Using Behavioral Economics Insights in Incentives, Rewards, and Recognition: A Nudge Guide," or to download the white paper, "How to Effectively Harness Behavioral Economics to Drive Employee Performance and Engagement," please visit: http://theirf.org/research/how-to-effectively-harness-behavioral-economics-to-drive-employee-performance-and-engagement/2072/

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About the IRF: The Incentive Research Foundation (TheIRF.org) funds and promotes research to advance the science and enhance the awareness and appropriate application of motivation and incentives in business and industry globally. The goal is to increase the understanding, effective use, and resultant benefits of incentives to businesses that currently use incentives and others interested in improved performance.

For the original version on PRWeb visit: http://www.prweb.com/releases/2017/05/prweb14375978.htm

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IRF Report Details Recommendations for Translating the Neuroscience of Behavioral Economics into Employee ... - Benzinga