Category Archives: Neuroscience

How to protect your mental health during the coronavirus pandemic – London Post

The coronavirus pandemic is creating stress in the global population. Empty store shelves, fear about the disease and quarantine or self-isolation can negatively impact depression and anxiety. The mental health implications of the pandemic will impact everyone differently, and clinical psychologists at Flow Neuroscience have offered a guide to support and manage ones mental health and those of others during these times.

Global concern about coronavirus means its very important to keep the normal routine as much as possible when it comes to sleep, nutrition and exercise, particularly in people with existing mental health problems, says Daniel Mansson, clinical psychologist and co-founder of Flow Neuroscience. In the current situation, finding ways to maintain your normal routine is essential to reducing stress and potential depressive thoughts that may appear.

First things first filter news and social media

The constant news about the pandemic can feel relentless and may exacerbate existing mental health problems. Be careful about the balance of watching important news and the news that could cause you to feel depressed. Seek trusted information, such as the NHS website, at specific times to take practical steps to protect yourself and loved ones. Have breaks from social media and mute triggering keywords and accounts.

Talk openly

Some people might feel that talking about their depression and anxiety requires no additional attention during these unprecedented times. People should be encouraged to talk about their feelings. Various support helplines are available, including Samaritans, as well as mental health crisis services, details of which can be found via the mental health charity Mind.

Eat an anti-depression diet

Anxiety is likely to increase during the current crisis, but a well-nourished body is better at handling stress. Traditional Mediterranean food, sometimes referred to as the anti-depression diet, for its anti-oxidant and anti-inflammatory properties, includes whole grains, vegetables (particularly green leaves), fruit, berries, nuts (including almonds), seeds and olive oil. The Flow app, free to download on iOS and Android, can help people to improve their nutrition and reduce the risk of depression at home.

Get therapeutic sleep

90% of depressed people struggle with sleep, which is likely to increase with fears over coronavirus. Good quality sleep is a form of overnight therapy, and increases the chance of handling strong emotions. Try to wake up and go to bed at the same time every day. Achieving 8 hours of sleep, taking a hot bath, setting the bedroom temperature to 18 degrees and having no screen time 2 hours before bedtime will also help.

Exercise as depression treatment

With months of the coronavirus pandemic ahead, it is important to keep exercising. Clinical studies show that regular exercise produces chemicals, such as dopamine and serotonin, which are as effective as antidepressant medication or psychotherapy for treating milder depression. Most people will not have access to a gym during the crisis, so it is important to create a daily exercise routine at home. Experts recommend between 30-40 minutes of exercise, 3-4 times a week to work up a sweat. People with depression often struggle with exercise, so start small with a 10 minute walk, then add a few minutes daily.

Home treatment for depression with brain stimulation

If you are suffering from clinical depression, it is important to contact your doctor or psychologist should your symptoms worsen.

As the coronavirus epidemic approaches though, many NHS services will be strained to cope with the demand to save lives. A modern drug-free treatment for depression, which does not require NHS services, is available in the UK since June of 2019.

Created by Flow Neuroscience, the brain stimulation headset is the only one in the EU to be medically approved as a home treatment for depression. The headset uses tDCS, a type of brain stimulation which is now listed as a treatment for depression on the NHS website. Clinical studies published in the New England Journal of Medicine and the British Journal of Psychiatry showed that the type of tDCS brain stimulation used in the Flow headset had a similar impact to antidepressants

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How to protect your mental health during the coronavirus pandemic - London Post

Hooked to books? These happy reads are the best choice in the time of social distancing – YourStory

As the world rallies together to fight the COVID-19 pandemic, the International Day of Happiness - observed on March 20 - reminds us that staying optimistic, happy, and maintaining mental well-being is the need of the hour.

Remember the slew of memes on Happiness is? Well, its true for every individual. The word happiness can have any meaning some may find it in playing with a dog, taking a long nap, enjoying the rain, spending time in nature, drinking a cold glass of lassi on a summer day...the list goes on.

International Happiness Day is usually the day when the United Nations calls upon nations to approach public policies in ways that can improve the well-being of citizens. It is believed that to attain global happiness, economic development must be accompanied by social and environmental well-being.

As we focus on social distancing this week to shut down coronavirus, YS Weekender has curated a list of Happy Reads for you.

So, grab a cup of coffee, get cosy in your bed or sofa, and enjoy these books on motivation, happiness, and self-help.

The Happiness Project book was a year-long project, carried out by lawyer-turned-author, Gretchen Rubin.

Gretchen decided to dedicate a year to happiness, and The Happiness Project was the result. Published in 2009 and having spent close to two years on the New York Times bestsellers list, the book chronicles Gretchens adventures during the twelve months she spent test-driving the wisdom of the ages, current scientific research, and lessons from popular culture about how to be happier.

Photo Credits: Goodreads

During her journey, she made many discoveries novelty and challenge are powerful sources of happiness. She discovered that money can help buy happiness when spent wisely, outer order contributes to inner calm, and the very smallest of changes can make the biggest difference.

On her website, Gretchen says that her book has turned to a movement where people are creating groups to discuss their Happiness project with each other, and many professors, psychiatrists, and clergy have recommended her book in various book clubs.

Authored by renowned Harvard psychologist Daniel Gilbert, Stumbling on Happiness describes the shortcomings of imagination and illusions of foresight that causes people to misconceive their future and misestimate their satisfactions.

Photo Credits: Goodreads

With powerful insights, the New York Times bestseller book explains why we seem to know so little about the hearts and minds of the people we are about to become.

After experiencing a terrible panic attack on live television on Good Morning America, news anchor Dan Harris embarked on an unexpected journey through the worlds of spirituality and self-help, and discovered a way to become happier in the true sense.

Photo Credits: Goodreads

10% Happier delves in the outer reaches of neuroscience to the inner sanctum of network news to the bizarre fringes of Americas spiritual scene, and leaves you with a takeaway that could actually change your life.

For long now, Denmark has been regarded as the happiest country in the world. And hygge is the reason for it.

Photo Credits: Romireads

In this New York Times bestseller, The Little Book of Hygge, Meik helps you be more hygge: from picking the right lighting and planning a dinner party through to creating an emergency hygge kit and even how to dress.

Meik is the CEO of the Happiness Research Institute in Copenhagen, and has said that hygge is the magic ingredient that makes Danes the happiest nation in the world.

Author Russ Harris in his book, The Happiness Trap: Stop Struggling, Start Living, explains the way most people go about trying to find happiness, and end up making themselves miserable, driving the epidemics of stress, anxiety, and depression.

The empowering book showcases the insights and techniques of ACT (Acceptance and Commitment Therapy), a revolutionary new psychotherapy based on cutting-edge research in behavioural psychology.

Photo Credits: Goodreads

By clarifying your values and developing mindfulness, ACT helps you escape the happiness trap and find true satisfaction in life, the author says.

He presents the following techniques to help readers:

Reduce stress and worry

Handle painful feelings and thoughts more effectively

Break self-defeating habits

Overcome insecurity and self-doubt

Create a rich, full, and meaningful life

Spiritual leader The Dalai Lama dedicated all his life to peace-keeping. A Nobel Prize winner will tell you that happiness is the purpose of life, and that "the very motion of our life is towards happiness."

Photo Credits: Goodreads

Through conversations, stories, and meditation, he explores the many facets of everyday life, including relationships, loss, and the pursuit of wealth, to illustrate how to ride through life's obstacles with a deep and abiding source of inner peace.

(Edited by Asha Chowdary)

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Hooked to books? These happy reads are the best choice in the time of social distancing - YourStory

Researchers find key molecule that helps neurons maintain information in working memory – The Medical News

Reviewed by Emily Henderson, B.Sc.Mar 19 2020

Working memory, the ability to hold a thought in mind even through distraction, is the foundation of abstract reasoning and a defining characteristic of the human brain. It is also impaired in disorders such as schizophrenia and Alzheimer's disease.

Now Yale researchers have found a key molecule that helps neurons maintain information in working memory, which could lead to potential treatments for neurocognitive disorders, they report March 19 in the journal Neuron.

Working memory arises from neuronal circuits in the prefrontal cortex. We have been learning that these circuits have special molecular maintenance requirements."

Min Wang, senior research scientist in neuroscience, Yale University

Neurons in the prefrontal cortex excite each other to keep information "in mind." These circuits act as a sort of mental sketch pad, allowing us to remember that caramelized onions are cooking in the frying pan while we search the next room for a pair of scissors.

The new study shows that these prefrontal cortical circuits depend upon the neurotransmitter acetylcholine stimulating muscarinic M1 receptors aligned on the surface of neurons of the prefrontal cortex. Blocking muscarinic M1 receptors reduced the firing of neurons involved in working memory, while activating the M1 receptors helped restore neuronal firing. Because acetylcholine actions at M1 receptors are reduced in schizophrenia and Alzheimer's disease, the M1 receptor may serve as a potential therapeutic target, the authors suggest.

Wang notes that a drug currently under development for the treatment of schizophrenia stimulates this M1 receptor and has shown promise in early clinical trials.

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Researchers find key molecule that helps neurons maintain information in working memory - The Medical News

Dr. Lisbeth Nielsen to lead NIA’s Division of Behavioral and Social Research – National Institute on Aging

On March 1, 2020, NIA appointed Lisbeth Nielsen, Ph.D., as its new Division of Behavioral and Social Research (BSR) director. Nielsen has a long history of leadership in the behavioral and social sciences at NIH: She served for 15 years as a program director and branch chief of the NIA BSR Individual Behavioral Processes Branch. She also held leadership roles in the NIH Science of Behavior Change Common Fund program and the trans-NIH Basic Behavioral and Social Sciences Opportunity Network. Prior to joining NIH, Nielsen conducted research in the affective and decision science of aging at Stanford University.

Throughout her research career, Nielsen has built bridges linking psychological and behavioral science to economics, genetics, neuroscience, biology, epidemiology, social science, and biomedicine, at all levels from basic to translational research. She was instrumental in launching new areas of research in subjective well-being and the social, affective, and economic neurosciences of aging.

Nielsen helped initiate several innovative research networks linking behavioral and population scientists to tackle questions related to the influences of stress on physical health and on the potential for midlife reversibility of health risks associated with early life adversity. She is an advocate for the study of aging processes across the full life course, including research on early life influences on later life outcomes and on processes in midlife that play a causal role in shaping trajectories of aging.

Dr. Nielsens efforts have enhanced the impact of aging-related research and created meaningful opportunities for behavioral and social scientists to participate in high-level and significant NIH scientific initiatives, said NIA Director Richard J. Hodes, M.D. Her impressive and accomplished background and experiences make her exceptionally qualified to lead this important division at a time of great scientific opportunity.

NIAs Division of Behavioral and Social Research is among the most influential and exciting behavioral and social science funding organizations in the U.S., and I look forward to leading our talented and creative staff, Nielsen said. Our work will continue to evolve to encompass a wide range of behavioral and social science approaches to understanding Alzheimers disease and related dementias, embracing life course research on the developmental origins of aging processes, extending our focus on midlife prevention of the chronic diseases of aging, and promoting a range of rigorous mechanistic approaches to understanding and advancing behavior change at the individual and organizational levels.

Nielsen also highlighted the divisions role in integrating life-span developmental and social science approaches into the broader geroscience agenda, to understand how behavior and the social environment impact the life span, health span, and the development of age-related diseases, including Alzheimers disease.

Multiple approaches from molecular to social are needed to understand individual and group differences in the pace of aging, and to tackle the growing and disturbingly large health disparities in the United States, a topic that has always been at the forefront of BSR efforts, said Nielsen.

Nielsen earned her Ph.D. in cognitive psychology and cognitive science from the University of Arizona, a masters degree in psychology from Copenhagen University, and a B.A. in philosophy from Rhodes College. She is a fellow of the Academy of Behavioral Medicine Research, the Association for Psychological Science, and the Mind and Life Institute.

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Dr. Lisbeth Nielsen to lead NIA's Division of Behavioral and Social Research - National Institute on Aging

Scientists find a potential biomarker that predicts reductions in anxiety symptoms following treatment – PsyPost

The gray matter volume of a brain region involved in fear and avoidance responses appears to predict treatment outcomes in patients with anxiety disorders, according to new research published in Neuropsychopharmacology.

Anxiety disorders are among the most prevalent mental health conditions in the US and are associated with significant economic burden worldwide, explained study author Katie Burkhouse, an assistant professor of psychiatry at the University of Illinois at Chicago and head of the Families, Affective Neuroscience, and Mood Disorders Lab.

Unfortunately, despite decades of research, many individuals do not respond to our first-line treatments for anxiety disorders, such as SSRIs (such as Prozac and Celexa) or cognitive behavioral therapy (CBT), especially patients presenting with more than one mental health disorder. Thus, the primary objective of this research was to identify a brain-based predictor of treatment response for patients with comorbid anxiety disorders in an attempt to use this information to guide patients toward treatments that have the highest likelihood of success.

In the study, 81 participants with a current anxiety disorder were randomly assigned to receive either 12 weeks of CBT or SSRI treatment. The researchers used magnetic resonance imaging to measure the gray matter volume of the amygdala, nucleus accumbens, and ventromedial prefrontal cortex prior to treatment.

After controlling for age, sex, and total brain volume, the researchers found that participants with greater nucleus accumbens volume prior to treatment tended to see greater reductions in anxiety symptoms after the 12 weeks. The results were similar for both CBT and SSRI treatment.

In our study, we explored whether brain volume of regions supporting fear and avoidance responses, which are heavily impacted in anxiety disorders, may be used to predict which individuals respond to treatment. We found that for adults with anxiety, the individuals that responded best to psychosocial or SSRI treatment were those who had greater pre-treatment volume in the nucleus accumbens, a region that plays a key role in both passive and active avoidance behavior, Burkhouse told PsyPost.

The researchers replicated their results in another experiment with 55 youth who were between the ages of 7 and 19.

The novel piece of our study was the ability to reproduce this effect in a separate sample of children and adolescents with anxiety disorders. Thus, improving avoidance responses may be one way in which these first-line treatments work for reducing anxiety among youth and adults, and these effects may be most meaningful for individuals who exhibit greater pre-treatment deficits in neural systems underlying avoidance behaviors, Burkhouse said.

But the study like all research includes some limitations.

Although the focus on patients with anxiety disorders and comorbid conditions (e.g., multiple anxiety disorders or anxiety with depression) was intentional to increase the generalizability of the current findings to the community and to understand predictors of treatment response for this population, we were unable to examine whether the effects were specific to a certain anxiety diagnosis (such as social anxiety or generalized anxiety), Burkhouse explained.

Future studies should explore whether findings are specific to comorbid anxiety profiles or are observed for specific diagnoses. Additionally, although we were able to reproduce our treatment finding in a separate sample, the total proportion of variance in treatment outcome explained by our brain-based predictor was still relatively low (approximately 20%), which is not uncommon for treatment outcome studies.

Thus, continued work in this area is needed to improve prediction models. For example, combining structural data (e.g., brain volume) with other measures of threat processing and avoidance behaviors (e.g., functional neuroimaging) may result in improved accuracy and prediction in future anxiety treatment outcome studies, Burkhouse said.

The nucleus accumbens has long been associated with motivation and reward. The brain structure might be related to vulnerability to stress as well, and it also appears to be involved in emitting or withholding a response to avoid harm.

The present study benefited from the ability to reproduce the treatment prediction finding in a distinct sample of youth with anxiety disorders. Given that anxiety disorders are most likely to onset during childhood and adolescence, identifying predictors of response to treatment for this developmental population is essential, Burkhouse added.

To our knowledge, this is the first study to include a separate independent sample when testing neural predictors of treatment response. The ability to reproduce findings in separate samples is critical for advancing the field of precision medicine.

The study, Nucleus accumbens volume as a predictor of anxiety symptom improvement following CBT and SSRI treatment in two independent samples, was authored by Katie L. Burkhouse, Jagan Jimmy, Nicholas Defelice, Heide Klumpp, Olusola Ajilore, Bobby Hosseini, Kate D. Fitzgerald, Christopher S. Monk, and K. Luan Phan.

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Scientists find a potential biomarker that predicts reductions in anxiety symptoms following treatment - PsyPost

Cross (the) country: Sophomore will go the distance for cancer patients – Binghamton University

By Jennifer Micale

March 17, 2020

You cant outrun cancer, as Annalise Jarski well knows.

She never met her grandfather, who died of lung cancer shortly after her birth. Still, he remained a presence, the center of a yearly family ceremony at the beachside rock where his ashes were strewn.

Through the years, the disease touched the sophomore integrative neuroscience major in other ways. Her family adopted a neighbors cat, after the woman succumbed to the illness. A family friend and an aunt passed away, and her grandmother also faced a diagnosis.

Thats why Jarski is lacing up her sneakers this summer and running across North America as part of 4K for Cancer.

A lot of people I know have been diagnosed with cancer, so its good to be doing something that has a larger impact, she said.

A program of the Ulman Foundation, which benefits young people with the disease, the run is far longer than the 5K races that Jarski competed in as part of her high school cross-country team in Westwood, N.J. The 2,800-mile trek is completed relay-style by three teams of 18- to 25-year-olds; two other teams bike the route. Each participant has to raise $4,500 to participate or $1 per kilometer, Jarski explained.

The run lasts from June 21 through August 8, and spans the distance between Baltimore and San Francisco. Participants go from town to town, with each runner completing anywhere from 6 to 16 miles a day and resting in the accompanying van in between.

Jarski is also a leg leader, responsible for arranging accommodations at host sites such as churches or community centers. There are other stops, too, including hospitals to award scholarships to cancer patients.

While she will share the burden with fellow runners, she acknowledges the journey will be a hard slog at times.

I know there will be days when Im going to want to stop. So Im going to think about the people who cant do what Im doing right now.

Binghamton University sophomore Annalise Jarski stands on the campus track. Image Credit: Jonathan Cohen.

Campus connections

A member of both the running and triathlon clubs on campus, Annalise discovered 4K for Cancer while researching trail runs near home. At first, the distance seemed insurmountable, but she was lured by the challenge.

They gave me a training plan and Im following it loosely. Im also doing cross-training to get stronger and prevent injuries, she said. Ive been trying to step up my mileage. I signed up for a half-marathon in April at home; Im trying to do something every day.

She contacted friends and family for her fundraising efforts, and also held a sneaker drive in her hometown. Binghamton University President Harvey Stenger also donated to the cause. Community members who would like to contribute can visit her online fundraising site.

I think its going to be one of those things you only do once, she said of her epic run. Everyone has been so supportive.

When it came time to choose a college path, she initially thought small-scale, drawing on her experiences at a small high school. A cousin who attends Binghamton University recommended its top-notch science programs, and Jarski found a larger university to be the right choice, both academically and personally.

I really love the outdoors and the Nature Preserve was a selling point, she said. I looked at smaller schools, but this seemed large and homey. I know I could have a lot of experiences I could partake in.

So far on her educational journey, she has found inspiration in David Werners drugs and behavior class, which led to her current major, and environmental studies adjunct faculty member and advisor Susan Ryan, who helped cultivate her interest in that field.

Jarskis interests span both neuroscience and environmental science, and shes currently considering a double-major. At Binghamton, she has enjoyed classes in both subjects, and is weighing potential career paths as a physicians assistant, perhaps, or as an environmental epidemiologist.

Environmental preservation and the conservation of resources are really important to me. Im looking for a way to combine the two, she explained. Im looking into the healthcare field and seeing how it relates to the environment.

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Cross (the) country: Sophomore will go the distance for cancer patients - Binghamton University

What We Can Learn From How Emotional Pain Affects the Brain – Thrive Global

The human brain exhibits amnesiawhen called upon to reexperience the blows from sticks and stones. With humiliation and indignity, however, the brain is a steel trap of merciless memory.

It should come as no surprise that victims of hate crimes suffer greater emotional distress and cumulative psychological harm than victims of non-bias-motivated crimes. Indeed, five years after the traumatic encounters, they experience greater levels of depression and anxiety than other crime victims. The impact to both mind and body lingers much longer. The incidence of severe trauma from hate crimes requires a lengthier recovery periodif recovery is even possible at all.

Similarly, hate crime victims report that their reintegration into society is much more difficult to achieve. Deprived of self-respect after experiencing ordeals of indignity, victims of hate speech struggle with the everyday tasks of socialization. One obvious outcome is in trying to be less visible, which the hate crime victim achieves by moving to an entirely different environment.

In this way, hate speech serves to undermine free speech itself precisely because it silences the targeted group, compelling them to disappear socially.

Moreover, even watching someone else experiencing pain can create greater sensitivity in ones own pain perception. So finely calibrated is the processing of emotions in the human brain, it turns out that showing empathy to a fellow human being carries some emotional risk. In a 2009 study conducted simultaneously at the universities of Arizona and Maryland, researchers discovered that the anterior cingulate cortex, the region of the brain that regulates emotional reactions, responds to an emotional insult by unleashing a wide variety of physical responsesstress-induced sensations in the chest, muscle tightness, an increased heart rate, and stomach painsall triggered from the same sector of the brain. Another study undertaken by two professors from the University of Virginia in 2006 supported the finding that activation in the anterior cingulate cortex coincides with the onset of chest pains. The researchers concluded that emotional pain involves the same brain regions as physical pain, suggesting that the two are inextricably linked.

In fact, medical evidence abounds showing how emotion and physical harm share the same circuitry in the human brain. The New England Journal of Medicine published a research study in 2013 on how subjects experienced both physical and emotional pain by looking at a photo of a cherished person who died. Brain scans indicated the same neural activity when a subject was exposed to heat on his or her forearm as when shown a photo of a lost loved one. Experiencing physical pain did not yield a separate neural response that was distinguishable from emotional pain. A burned forearm and an aggrieved heart elicited identical neural reactions. One of the researchers on the study, Tor Wagner, a professor of neuroscience at the University of Colorado in Boulder, explained the reasons for this unexpected outcome, stating [t]hat may be why social pain is so painful: every time you remember it, you feel it all over again and that is not true for physical pain. Of all the things Ive observed in the brain, nothing is more similar to physical pain than social pain.

And the consequences of social pain are even more severe. The pain from social exclusion and indignity, which begins with emotional distress, ends up rendering a person physically sick. The two regions of the brain once thought to be the epicenter for the processing of physical pain show similar patterns of neural activity when the mind focuses on a photograph reminiscent of rejection or loss. A research team from the University of Kentucky set out to demonstrate this neural overlap between social and physical pain systems. Apparently, the same behavioral and neural mechanisms are at work in processing what many would believe to be disparate manifestations of pain. Psychology professor C. Nathan DeWall explained the significance of his teams findings in 2009: Social pain, such as chronic loneliness, damages health as much as smoking and obesity. We hope our findings can pave the way for interventions designed to reduce the pain of social rejection. He also speculated about the reasons why the human brain evolved in this manner. Instead of creating an entirely new system to respond to social hurt, he said, evolution piggybacked the system for emotional pain onto that for physical pain. The evolution of the human brain allowed emotional injury to take a free ride on the circuitry associated with physical pain.

And not surprisingly, when it comes to hate crimes and their origins in racial bigotry, the overall bodily damage arising from such injurious speech tends to be even worse. Law professor Richard Delgado noted that, [i]n addition to these long-term psychological harms of racial labeling, the stresses of racial abuse may have physical consequences. There is evidence that high blood pressure is associated with inhibited, constrained or restricted anger . . . American blacks have higher blood pressure levels, and higher morbidity and mortality rates from hypertension, hyper-intensive disease, and stroke than do white counterparts. Further, there exists a strong correlation between degree of darkness of skin for blacks and level of stress felt, a correlation that may be caused by the greater discrimination experienced by dark-skinned people.

Psychology professor Geoff MacDonald, from the University of Toronto, has charted the trajectory of bodily and psychological harm caused by social insult. He noted that, not unlike damage done to the body, the initial sensation of emotional hurt produces a surge of stress hormones. In the context of a physical injury, the purpose of this hormone is to brace the body for yet another attack. It provides confidence to both body and mind that the individual can actually take and survive a punch. The release of these stress hormones accounts for why a person can actually walk away on a broken leg or manage to speak despite having a shattered skull. After the surge of this energy dissipates, the pain ensues. The same release of stress hormones occurs when a person faces severe emotional, social pain. Proving the Talmudic injunction not to humiliate a fellow human being because it is tantamount to draining him of his blood, neuroscience can now account for how the ancients knew something about what happens, physiologically, to human beings who have experienced severe indignity. The brain discharges a sufficient amount of stress hormones to handle the first blow. When the damage is done and the insult has subsided, the body will begin the process of dissipating the pain, and the blood flows away from the afflicted area.

The difference, however, is that, unlike physical pain, where bones will ultimately heal, and the pain of the experience will become wholly forgotten, social pain can beand often isrelived over and over again. The sensation of the pain is instantly recalled and reexperienced. This is the consequence of how our memories cope with traumatic stress, resulting in a cruel admixture of the mind. Physical pain, by contrast, can be remembered as once being painful, but the pain itself cannot be reclaimed. The human brain exhibits amnesia when called upon to reexperience the blows from sticks and stones. With humiliation and indignity, however, the brain is a steel trap of merciless memory.

With sets of patients who had experienced physical injury and another group that suffered from emotional harm, researchers at Purdue University did a five-year study and checked back in with the participants each year after the incidents that caused them such pain. The focus of the study was to determine how they felt about what they had experienced five years earlier. The results, published in 2008, were not surprising to neuroscientists but surely would be perplexing to emotionally adverse judges. Those participants who had experienced emotional injury reported higher levels of pain than participants who experienced physical harm. They were still feeling the emotional effects of the harm. Psychology professor Kip Williams of Purdue stated that, While both types of pain can hurt very much at the time they occur, social pain has the unique ability to come back over and over again, whereas physical pain lingers only as an awareness that it was indeed at one time painful. A few law professors had been making similar points over the years, with much skepticism from their colleagues and the courts. It must have just seemed intuitively obvious. Arkes, for instance, once presciently wrote during the Stone Age of such speculations (in 1974), There is in fact such a thing as a psychological injury, which may be quite grave . . . as an assault on ones body or a broken leg.

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What We Can Learn From How Emotional Pain Affects the Brain - Thrive Global

How to protect your mental health during the coronavirus pandemic Northern Life – Northern Life magazine

The coronavirus pandemic is creating stress in the global population. Empty store shelves, fear about the disease and quarantine or self-isolation can negatively impact depression and anxiety. The mental health implications of the pandemic will impact everyone differently, and clinical psychologists at Flow Neuroscience have offered a guide to support andmanage ones mental health and those of others during these times.

Globalconcern about coronavirus means its very important to keep the normal routineas much as possible when it comes to sleep, nutrition and exercise,particularly in people with existing mental health problems, says DanielMansson, clinical psychologist and co-founder of Flow Neuroscience. In thecurrent situation, finding ways to maintain your normal routine is essential toreducing stress and potential depressive thoughts that may appear.

Theconstant news about the pandemic can feel relentless and may exacerbate existingmental health problems. Be careful about the balance of watching important newsand the news that could cause you to feel depressed. Seek trusted information,such as the NHS website, at specific times to take practical steps to protectyourself and loved ones. Have breaks from social media and mute triggeringkeywords and accounts.

Somepeople might feel that talking about their depression and anxiety requires noadditional attention during these unprecedented times. People should beencouraged to talk about their feelings. Various support helplines areavailable, including Samaritans, as well as mental health crisis services, details ofwhich can be found via the mental health charity Mind.

Anxietyis likely to increase during the current crisis, but a well-nourished body isbetter at handling stress. Traditional Mediterranean food, sometimes referredto as the anti-depression diet, for its anti-oxidant and anti-inflammatoryproperties, includes whole grains, vegetables (particularly green leaves),fruit, berries, nuts (including almonds), seeds and olive oil. The Flow app,free to download on iOSand Android, can help people to improve their nutrition and reduce the risk ofdepression at home.

90%of depressed people struggle with sleep, which is likely to increase with fearsover coronavirus. Good quality sleep is a form of overnight therapy, andincreases the chance of handling strong emotions. Try to wake up and go to bedat the same time every day. Achieving 8 hours of sleep, taking a hot bath,setting the bedroom temperature to 18 degrees and having no screen time 2 hoursbefore bedtime will also help.

Withmonths of the coronavirus pandemic ahead, it is important to keep exercising.Clinical studies show that regular exercise produces chemicals, such asdopamine and serotonin, which are as effective as antidepressant medication orpsychotherapy for treating milder depression. Most people will not have accessto a gym during the crisis, so it is important to create a daily exerciseroutine at home. Experts recommend between 30-40 minutes of exercise, 3-4 timesa week to work up a sweat. People with depression often struggle with exercise,so start small with a 10 minute walk, then add a few minutes daily.

Ifyou are suffering from clinical depression, it is important to contact your doctoror psychologist should your symptoms worsen.

Asthe coronavirus epidemic approaches though, many NHS services will be strainedto cope with the demand to save lives. A modern drug-free treatment fordepression, which does not require NHS services, is available in the UK sinceJune of 2019.

Createdby Flow Neuroscience, the brain stimulation headset is the only one in the EUto be medically approved as a home treatment for depression. The headset usestDCS, a type of brain stimulation which is now listed as a treatment fordepression on the NHS website. Clinical studies published in the New England Journalof Medicine and the British Journal of Psychiatry showed that the type of tDCSbrain stimulation used in the Flow headset had a similar impact toantidepressants 1,2,3 More information about the Flow headset can befound here.

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How to protect your mental health during the coronavirus pandemic Northern Life - Northern Life magazine

The Neural Basis of Tremors – Technology Networks

New insight on what happens in brain cells to cause tremors in mice has been published in the open-access journal eLife.Uncontrollable movements called tremors are common and debilitating, but scientists have previously struggled to pinpoint their exact cause. The new study reveals the neural activity behind tremors, and suggests that targeting deep brain stimulation (DBS) to the cerebellum can help treat the condition. DBS is a technique used to treat movement disorders in patients who do not respond well enough to medications.

While abnormalities in different brain cells in the cerebellum, particularly Purkinje cells, have previously been associated with tremors, it wasnt certain if and how Purkinje cells cause this condition, says lead author Amanda Brown, a graduate student in the Department of Neuroscience at Baylor College of Medicine in Houston, Texas, US.

To investigate this further, Brown and her colleagues studied mice with Purkinje cells that were unable to signal correctly. They then treated the mice with a drug that usually causes tremors and found that the animals did not develop the condition.

Next, they administered the drug to healthy mice and measured what happened in their Purkinje cells. They found that the animals tremors coincided with abnormal bursts of activity in these cells. Using a technique called optogenetics, the team recreated these abnormal bursts in the Purkinje cells in untreated, healthy mice and found that this also led to tremors.

Finally, they showed that targeting DBS to the cerebellum where Purkinje cells are located could stop tremors in mice treated with the tremor-inducing drug. DBS that targets part of the brain called the thalamus, which receives messages from the cerebellum, is already used to treat movement disorders in people, Brown explains. But these findings highlight the cerebellum as a more direct potential target.

Our study hints at a potential treatment option to reduce or curb tremors and other movement disorders involving the cerebellum, adds senior author Roy Sillitoe, Associate Professor of Pathology at Baylor College of Medicine. Our next step is to explore whether cerebellar deep brain stimulation works as well in humans with tremors as in mice.ReferenceBrown et al. (2020) Purkinje cell misfiring generates high-amplitude action tremors that are corrected by cerebellar deep brain stimulation. eLife. DOI: https://doi.org/10.7554/eLife.51928

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How to spot bogus science stories and read the news like a scientist – The Conversation UK

When fake news, misreporting and alternative facts are everywhere, reading the news can be a challenge. Not only is there plenty of misinformation about the coronavirus pandemic, climate change and other scientific topics floating around social media, you also need to read science stories, even well-known publications, with caution.

We have already seen headlines suggesting that coronavirus vaccines are imminent, while scientists desperately try to manage expectations that its more likely to take more than a year for vaccines to be suitable for use. So how do we approach science news like a scientist, to see past the sensational and find the facts?

In a recent study, we and our colleagues analysed 520 academic papers and the media articles that reported their findings. We wanted to trace how the presentation of scientific knowledge as it makes its way from researchers to the general public via the media.

Read more: We're climate researchers and our work was turned into fake news

We found that scientific knowledge is sometimes reproduced but is most often reinterpreted and its meaning is frequently lost in translation. Based on this study, we think there are some key things that readers of the news can do to spot when science is being reported in a misleading or inaccurate way, and get to what the evidence really shows.

In our research we saw that content transformation can happen in a number of ways. The main focus of a study is often changed in a way that makes assumptions about how the results might effect people, even in cases when this was not an aim of the research. For example, research in rats is often taken to have implications in humans.

Highly technical language can be changed not just to more common phrases but also more evocative or sensational descriptions. Charts and graphs are replaced with images that make articles appear more related to human experimentation or applications, even where this isnt the case.

One example we looked at in detail was a report on the Mail Online website from 2016 that said brain implants could soon help us develop superhero night vision. The report stated that scientists have used brain implants to give rats a sixth-sense that enables them to detect and react to the normally invisible light source. It added that would make it possible for the adult brain to adapt to new forms of input and opens up the possibility of enabling humans to gain an array of superhuman senses.

An exciting revelation indeed. But if this was such a groundbreaking and impactful development, why did so few other news publishers cover it?

The research the story was based on had originally been published in the Journal of Neuroscience by a team of scientists at Duke University Medical Centre in the United States. Their work explored how easily you could change the sensory processing of adult rats by implanting them with a brain device to teach them to identify the location of infrared light sources. Surprisingly, the implanted rats learned to do so in less than four days.

The scientists who conducted the research suggested their findings could have important implications for basic neuroscience and rehabilitative medicine. But the Mail Online article took this to another level and interpreted this as the possibility of giving people a number of superhuman senses.

The experiment had previously been reported in New Scientist, which appeared to be the main source of information for the report published in the Mail Online. The New Scientist article did focus on the rats but said the research paved the way for human brain augmentation. The article used images representing human mind control. It was then less of a leap for the Mail Online to report the research as a move towards giving people superhuman powers.

All this leaves ordinary readers to try to work out what is accurate and what isnt. This requires them to read like a scientist but without the same training.

So how do we read this way? Based on our research, we have put together six steps to help you read in a critical way when engaging with scientific information.

The first thing to do is simply be aware of how important information in the original source may be reinterpreted, modified and even ignored altogether depending on what a journalist understands or chooses to present. This is a bit like the game telephone or Chinese whispers.

In particular, you should watch out for big or surprising claims that may be exaggerated (such as giving people a sixth sense). Such extraordinary claims require extraordinary evidence.

Check how precise and unambiguous the details presented in the article about the research are. Saying that an experiment has proven a particular fact is a lot stronger than saying it suggests that something might happen in the future.

Look for a reference or a link to the original source in the report youre reading, like the ones provided in this text. If there is one its more likely that the journalist has read the original research and understands what it does and doesnt say.

Try to check whether the arguments in the article come from the scientists who carried out the research or the journalist. This could mean looking for quotes or comparing with the original research paper, if you can do that.

Look to see if other places are reporting the same stories. If only one news outlet is covering an amazing breakthrough, it might be time to apply a little more scepticism.

Developing these skills could help you discern what sources you should and shouldnt trust, and how to spot when even usually authoritative outlets sometimes exaggerate or misinterpret things.

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How to spot bogus science stories and read the news like a scientist - The Conversation UK