Category Archives: Neuroscience

Neuroscience

Eyes impart a sudden sign to the mind – Microbioz India

For quite a long time, science course readings have expressed that eyes speak with the cerebrum solely through one sort of flagging pathway. In any case, another disclosure shows that some retinal neurons take a street less voyaged.

New research, drove by Northwestern University, has discovered that a subset of retinal neurons imparts inhibitory signs to the mind. Previously, specialists accepted the eye just imparts excitatory signs. (Basically: Excitatory flagging makes neurons to fire progressively; inhibitory flagging makes neurons to fire less.)

The Northwestern specialists likewise found that this subset of retinal neurons is associated with subliminal practices, for example, synchronization of circadian rhythms to light/dull cycles and understudy narrowing to exceptional brilliant lights. By better seeing how these neurons work, specialists can investigate new pathways by which light impacts our conduct.

These inhibitory signs keep our circadian clock from resetting to diminish light and forestall understudy choking in low light, the two of which are versatile for legitimate vision and day by day work, said Northwesterns Tiffany Schmidt, who drove the exploration. We imagine that our outcomes give a component to understanding why our eye is so perfectly touchy to light, however our subliminal practices are similarly obtuse toward light.

The exploration will be distributed in the May 1 issue of the diary Science.

Schmidt is an associate teacher of neurobiology at Northwesterns Weinberg College of Arts and Sciences. Takuma Sonoda, a previous Ph.D. understudy in the Northwestern University Interdepartmental Neuroscience program, is the papers first creator.

To direct the investigation, Schmidt and her group obstructed the retinal neurons answerable for inhibitory motioning in a mouse model. At the point when this sign was blocked, diminish light was progressively viable at moving the mices circadian rhythms.

This recommends there is a sign from the eye that effectively hinders circadian rhythms realignment when ecological light changes, which was startling, Schmidt said. This bodes well, notwithstanding, on the grounds that you would prefer not to alter your bodys whole check for minor annoyances in the natural light/dull cycle, you possibly need this gigantic acclimation to occur if the adjustment in lighting is powerful.

Schmidts group likewise found that, when the inhibitory signs from the eye were hindered, mices understudies were considerably more touchy to light.

Our working speculation is that this component shields understudies from contracting in low light, Sonoda said. This builds the measure of light hitting your retina, and makes it simpler to find in low light conditions. This instrument clarifies, in least part, why your students abstain from tightening until splendid light increases.

The examination, A non-standard inhibitory circuit hoses conduct affectability to light, was upheld by a Klingenstein-Simons Fellowship in the Neurosciences, the Alfred P. Sloan Foundation and the National Institutes of Health (grant numbers 1DP2EY022584, T32 EY025202 and F31 EY030360-01).

Story Source:Materials provided by Northwestern Universityand Content may be edited for style and length.

Journal Reference:1. Takuma Sonoda, Jennifer Y. Li, Nikolas W. Hayes, Jonathan C. Chan, Yudai Okabe, Stephane Belin, Homaira Nawabi, Tiffany M. Schmidt. A non-canonical inhibitory circuit dampens behavioral sensitivity to light. Science, 2020 DOI: 10.1126/science.aay3152

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Eyes impart a sudden sign to the mind - Microbioz India

Neuroscience

Marconi Prize honors Andrea Goldsmith as pioneer in wireless communications – Princeton University

Andrea Goldsmith, a global leader in the development of wireless systems, has been awarded the Marconi Prize, the highest honor in telecommunications research. She is the first woman ever to win the prize, now in its 45th year.

Goldsmith was recently appointed dean of Princeton's School of Engineering and Applied Science, effective Sept. 1, and named the Arthur LeGrand Doty Professor of Electrical Engineering. In addition to being widely recognized for her contributions to communications and information theory, she has co-founded and served as chief technical officer for Quantenna Communications and Plume WiFi. She is a member of the National Academy of Engineering and the American Academy of Arts and Sciences. She holds 29 patents.

Photo of Goldsmith by Linda A. Cicero / Stanford News Service

Goldsmith's work has fundamentally shaped today's mobile technology and has laid ground rules for cellular and Wi-Fi network performance. Fluctuations in network capacity can arise from a variety of factors such as movement and shifts in demand. For example, walking while using a mobile phone creates a moving signal. Ebbs and flows of internet use create bottlenecks throughout the day. When data flows at a constant rate during these fluctuations, rather than reflecting the network's need, it creates problems including dropped calls and frozen screens. To address these problems, Goldsmith developed techniques that allow network designers to modulate speeds and match qualities across dynamic networks.

This adaptive modulation, implemented through Goldsmith's start-up ventures and the detailed descriptions she's published, have enabled engineers to leverage her findings across nearly every major cellular and Wi-Fi network in the world. The Marconi Prize comes in recognition for this work as she moves from Stanford University, where she is the Stephen Harris Professor in Engineering, to Princeton, where she will continue to lead research into information theory and communications systems, a core area of the Department of Electrical Engineering.

"Researchers from Princeton have had a major impact on today's communications technologies," Goldsmith said. "I'm thrilled to join, continue and build on that deep tradition, particularly at a moment when the value of connectivity could not be more apparent."

Goldsmith has written several books, including "Wireless Communications," "MIMO Wireless Communications" (referring to multiple-inputs, multiple-outputs systems) and "Principles of Cognitive Radio." In addition to wireless communications, her ongoing work focuses on cyberphysical systems and a range of signal-processing problems in neuroscience.

Andrea has enabled billions of consumers around the world to enjoy fast and reliable wireless service, as well as applications such as video streaming and autonomous vehicles that require stable network performance, Vint Cerf, chair of the Marconi Society and one of the founding designers of the internet, said in the society's announcement.

The prize includes an award of $100,000, which Goldsmith said she will donate back to the Marconi Society to start an endowment that will fund technology and diversity initiatives.

In addition to her contributions to research and business, the Marconi Prize recognizes Goldsmith's "leadership to radically improve diversity and inclusion in engineering," according to the Marconi Society. Goldsmith has said that during the 1980s, when she was an undergraduate at the University of California, Berkeley, women encountered a stringent gender bias at all levels of engineering. It wasn't until she met a female Ph.D. student, who was assisting the teaching of a math class, that Goldsmith found a model for women breaking through in a technical field. Throughout her career, she has strived to embody that same role for others, opening new pathways for women and other underrepresented groups across science, technology, engineering and mathematics.

I am so deeply honored and humbled to become a Marconi Fellow, said Goldsmith. "The Marconi Fellows are my professional heroes and the people I have looked up to my entire career for their immense impact on the communications technologies we have today."

She has held a number of positions with the Institute of Electrical and Electronics Engineers (IEEE), most recently as chair of the organizations Ad Hoc Committee on Diversity, Inclusion and Ethics. Under her guidance, the IEEE adopted its first-ever diversity statement and awarded five women with IEEE medals, the organization's most important honors. She led efforts within the Stanford Leadership Academy and the University Promotions and Appointments Advisory Board to develop best practices that improve recruitment and retention of diverse faculty; and served on the Stanford Faculty Womens Forum Steering Committee, a group focused on improving recruitment, retention, support and overall satisfaction of women faculty.

Goldsmith comes from a family that deeply valued creativity and problem solving. Her mother was an animator and character designer for "The Rocky and Bullwinkle Show." Her father, a Holocaust survivor, was a mechanical engineering professor at UC Berkeley and an authority on the physics of head and neck trauma. He testified as an expert witness during the 1992 trials of four police officers accused of beating Rodney King.

Goldsmith earned her bachelor's, master's and doctoral degrees in electrical engineering at UC Berkeley. She worked in the defense communications industry and taught at the California Institute of Technology before joining the Stanford faculty in 1999. In addition to her position in engineering, she is affiliated with Stanford's Wu Tsai Neurosciences Institute.

She joins Princeton's electrical engineering faculty and succeeds Emily A. Carter as dean on Sept. 1.

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Marconi Prize honors Andrea Goldsmith as pioneer in wireless communications - Princeton University

Neuroscience

Fund in memory of teenager who died of a brain tumour hits 100,000 with money found in his wallet – Yorkshire Post

HealthA group of fundraisers known as Team Jack was set up by Yorkshire teenager before he died of a tumour.

Tuesday, 28th April 2020, 11:45 am

Jack Faulkners family and friends remember most his caring nature, warm sense of humour and his ability to time an eye-roll so well, entire rooms would descend into hysterics.

Almost two years have passed since 15-year-old Jack from Totley was diagnosed with an incurable brain tumour which would sadly end his life.

The fundraising effort which sparked the TeamJack movement was instigated by the teenager himself, as he set up a JustGiving page whilst beginning chemotherapy on the dedicated neurosciences ward, Ward 5, at Sheffield Childrens Hospital.

The money raised quickly exceeded all expectations. Supporters took on a host of events, from races, sponsored walks and triathlons to bake sales and charity stalls. Local pubs held collections, long-lost friends reconnected to pledge support and hospital staff wore special Team Jack badges emblazoned on their uniforms.

More than 500 people attended the Totley teens funeral; and in the months since, an incredible group of men, women and children Jacks family, friends and local community raised nearly 100,000 in his name, far more than the 20,000 target originally set.

Inspired by the teenagers remarkable resilience, #TeamJack led by mumSally, and dadDan are determined that the life of their lovely boy will be an ongoing force for good, with every penny raised going to Sheffield Childrens Hospitals neurosciences ward.

As the latest milestone approached, the cancellation of planned events left the fundraising just short of their 100,000 target, which is when Sally thought of a fitting way Jack could round up what he began.

It makes me quite emotional to talk about it, but when Jack became ill, he sold his old phone to his Grandpa for 80. We had just left the money in his wallet I couldnt bring myself to touch it, says Sally.

When I found out we were short, I knew what we had to do. As well as being the joker everyone remembers, he also had a very caring side. Dan and I were sobbing down the phone when I suggested it, but it felt right. This has always been about him and its fitting that it was Jacks own money got us here.

Dan added: Having Jack take us across the line really hit home, it was a moving moment. What we have been able to achieve together has been nothing short of incredible. I would never have dreamed to raise so much, all in the name of a very courageous young man.

The money raised has been split between two causes close to Jacks heart, The Childrens Hospital Charity and CLIC Sargant. At Jacks request, the money raised for Sheffield Childrens Hospital has been dedicated to Ward 5 which provided his treatment.

The fundraising is already having a positive impact at Sheffield Childrens Hospital. Jack spent 79 nights continuously on the neurosciences ward and three of his suggestions for improvement; video games consoles, new curtains and two specially adapted wheelchairs have already been funded.

Its great that the ward now has some nicer surroundings and weve helped to make things brighter, says Sally. The Childrens Hospital Charity listened to Jacks suggestions and theyre already making a difference. For Jacks parents, the fundraising effort has helped them deal with the loss of their son.

After everything that happened when Jack passed, I felt lost, continues Sally. The fundraising gave us a sense of purpose and focus, to build on Jacks legacy and continue helping other people. Its just been amazing how many people have stepped forward and asked can I join Team Jack? Jacks friends have been phenomenal too. The support they have given his younger sister Emily at school has been amazing, its such a relief to know they will always look out for her.

Dan added: Being able to fundraise and train for events has personally allowed me to keep my focus. Without that kind of structure in my life, I honestly dont know what would have happened.

The Childrens Hospital Charitys team have been great, and TeamJack as a community has provided a sense of normality and allowed us to get to a point where we are in a good place. I know for sure, that what weve been through has brought us closer together and made us stronger.

We will continue to raise as much money as we can. The next milestone might take a little longer to reach, but it will be just as important.

As well as the fundraising, the family also held a TeamJack Snowflake Charity Ball in November. The nurses and doctors who cared for Jack attended free of charge as a gesture of thanks from the family. Mum Sally was also involved in organising last summers Neuroscience Family Fun Day at Graves Park in Sheffield, which raised over 4,700.

Rachael Thomas, events fundraising officer at The Childrens Hospital Charity added: I was really moved to find out that Jack himself helped the fundraising in his name reach this incredible total.

Were so thankful to everyone in TeamJack who continues to dedicate themselves tirelessly to this effort, which has already achieved so much. It is lovely to know that the fundraising has already been used to help improve the wards surroundings, particularly for older patients, in a legacy that is sure to last for generations to come.

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Fund in memory of teenager who died of a brain tumour hits 100,000 with money found in his wallet - Yorkshire Post

Neuroscience

Announcing the American Academy of Neurology 2020 Research Program Recipients – Newswise

Newswise MINNEAPOLIS The American Academy of Neurology (AAN), the worlds largest association of neurologists, is pleased to announce the recipients of the 2020 AAN Research Program. This years program has awarded more than $3 million toward neuroscience research and training.

Funding will support the following 2020 AAN Research Program recipients and projects:

Career Development Award Funded by the American Academy of Neurology Oluwole Awosika, MD, Cincinnati, Ohio Hugo Aparicio, MD, Boston, Mass.

Clinical Research Training Scholarship Funded by the American Academy of NeurologyMark Etherton, MD, PhD, Boston, Mass.Carlyn Patterson Gentile, MD, PhD, Philadelphia, Pa. David Lin, MD, Boston, Mass.

Clinical Research Training Scholarship in ALSFunded by The ALS Association and American Brain Foundation, in collaboration with the American Academy of NeurologySarah Berth, MD, PhD, Baltimore, Md.

Clinical Research Training Scholarships in Lewy Body DiseasesFunded by The Mary E. Groff Charitable Trust, the Alzheimers Association, and the American Brain Foundation, in collaboration with the American Academy of NeurologyLenora Higginbotham, MD, Atlanta, Ga.

Clinical Research Training Scholarship in Neuromuscular DiseaseFunded by the Muscle Study Group and the American Brain Foundation, in collaboration with the American Academy of NeurologyPaloma Gonzalez-Perez, MD, PhD, Boston, Mass.

Clinical Research Training Scholarship in Parkinson's DiseaseFunded by the Parkinsons Foundation and American Brain Foundation, in collaboration with the American Academy of NeurologyJames Curtis, MS, CCC-SLP, BCS-S, New York, N.Y.

Clinical Research Training Scholarship in Tourette SyndromeFunded by the Tourette Association of America and American Brain Foundation, in collaboration with the American Academy of NeurologyAlonso Zea Vera, MD, Cincinnati, Ohio

McKnight Clinical Translational Research Scholarship in Cognitive Aging and Age-Related Memory LossFunded by the McKnight Brain Research Foundation through the American Brain Foundation and the American Academy of NeurologyBryan Baxter, PhD, Boston, Mass.Sarah Getz, PhD, Miami, Fla.

Neuroscience Research Training ScholarshipFunded by the American Academy of NeurologyWilliam Zeiger, MD, PhD, Los Angeles, Calif.Richard Krolewski, MD, PhD, Boston, Mass.

Practice Research Training ScholarshipFunded by the American Academy of NeurologyDeanna Saylor, MD, Baltimore, Md.

Richard Olney Clinician Scientist Development Award in ALSFunded by The ALS Association and American Brain Foundation, in collaboration with the American Academy of NeurologyCollin Kreple, MD, PhD, Saint Louis, Mo.

Robert W. Katzman, MD Clinical Research Training Scholarship in Alzheimer's or Related DisordersFunded by the Alzheimers Association and the American Brain Foundation, in collaboration with the American Academy of NeurologyLawren VandeVrede, MD, PhD, San Francisco, Calif.

Susan Spencer, MD Clinical Research Training Scholarship in EpilepsyFunded by the American Epilepsy Society, the Epilepsy Foundation, and American Brain Foundation, in collaboration with the American Academy of NeurologyColin Ellis, MD, Philadelphia, Pa.

Clinician Scientist Development Award in Multiple SclerosisFunded by the National Multiple Sclerosis Society and American Brain FoundationFarinaz Safavi, MD, PhD, Bethesda, Md.

The American Academy of Neurology is the worlds largest association of neurologists and neuroscience professionals, with over 36,000 members. The AAN is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimers disease, stroke, migraine, multiple sclerosis, concussion, Parkinsons disease and epilepsy.

For more information about the American Academy of Neurology, visit AAN.com or find us on Facebook, Twitter, Instagram, LinkedIn and YouTube.

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Announcing the American Academy of Neurology 2020 Research Program Recipients - Newswise

Neuroscience

How to Work From Home, According to Neuroscience – Vanity Fair

I once heard a story from a book agent about an older gentleman who wrote novels for a living, and who did so working from a home office. The man would wake up each morning, go down for breakfast with his wife, and then go through a morning ritual that he had done every single weekday, without fail, for almost five decades. He would shower, shave, and then get dressed in a three-piece suit, replete with a bow tie and matching pocket square, grab his briefcase, and then kiss his wife goodbye, before walking about 10 feet into his home office, where he would close the door, and spend the morning writing. The man, apparently, had deduced that the only way to work from home was to act like he wasnt actually home. Self-deception is normally considered a psychopathologybut in the case of working from home, it actually might be the only way to maintain mental health, a mind game you have to play against yourself.

Science actually seems to back this up. Ive spoken to neuroscientists, psychologists, and technologists (along with plenty of writers) about this challenge, and while the approaches may be different, the reigning theory seems to be that you constantly have to trick yourself into thinking that you are not, in fact, at home. So getting dressed like the older gentleman is highly correlated with being productive. Granted, you dont need to wear a bow tie, or a pantsuit with high heels, but its advisable to tell yourself, and your brain, that youre now about to do something new, and an important first step is to get dressed each morning. But thats only the beginning.

Years ago, when I was struggling to juggle numerous work projects (writing a book and writing news stories and doing a podcast), I reached out to Gary Small, a professor of psychiatry at the Semel Institute for Neuroscience & Human Behavior, who told me that the brain is always going to find the path of least resistance to do something (us humans are pretty lazy at the end of the day, and our brains are no different), and so you have to trick yourself into being able to concentrate. Smalls advice was to allocate different places in the home that are dedicated work spaces for specific projects. For example, for me, when I worked on journalism-related pursuits, Small suggested sitting in one specific place, say a dedicated chair, and trying to place other markers that the brain would quickly identify nearby: a scented candle, a specific type of flower, anything that says, I am in this space, doing this thing. When I had to work on my book, the advice was to find a dedicated spot in my house to do that, with very different markers, a different kind of chair, another smell from a different candle, or even just an altered form of lighting. It doesnt take long for the brain to recognize that if youre working in one space, with all those little innocuous cues, youre working on one thing versus another. For me, it was a game changer. This theory is not saying you need to build a home office in your backyard in order to be productive; its simply saying: dont work from your bed or your couch. Find a place that is dedicated to work and nothing else. Even if its just a different seat.

Given how much of a role technology plays in our work lives, the tech we choose to use for work can also contribute to our ability to actually be productive. Applying Smalls theory that the brain finds associations with everything, I truly believe that working on your phone is disastrous and should be avoided at all costs. Think about it: We text with our friends on our phones, watch funny meme videos, rage-tweet at Donald Trump, flick through photos, swipe on dating apps, and then, on that same little device, we think we can clack out a really important work email? I never, ever, work on my phoneunless its an emergency.

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How to Work From Home, According to Neuroscience - Vanity Fair

Neuroscience

Researchers Move Toward Once-Yearly Treatment for HIV – HealthDay

THURSDAY, April 30, 2020 (HealthDay News) -- Researchers have reformulated an HIV medication into a version they hope can eventually be taken as infrequently as once a year.

The work is only in the early stages, having been studied in lab animals. But the goal is to create an HIV drug that can be injected annually -- offering protection from infection or control of the virus in people who already have it.

The researchers, at the University of Nebraska Medical Center in Omaha, started with a drug that is already in clinical trials, called cabotegravir. It's an injection drug being developed for both HIV prevention and treatment, and designed to be given once every month or two.

The investigators chemically modified cabotegravir to become a "prodrug" -- an inert substance that, once in the body, is converted into an active form. In this case, that conversion happens gradually, with the drug being released for up to a year in lab animals.

The findings, published online April 27 in the journal Nature Materials, are an initial step, and much more work remains.

"We haven't studied this in humans yet," said researcher Dr. Howard Gendelman, who heads the department of pharmacology and experimental neuroscience at the Nebraska center.

And it's hard to predict how long it could take to move ahead, according to Gendelman.

"We're repurposing a medication that other people invented," he said, and there will be "multiple facets" to getting it into human trials.

Cabotegravir is being developed by North Carolina-based ViiV Healthcare. It belongs to a relatively newer class of HIV drugs called integrase inhibitors. They work by blocking an enzyme the virus needs to replicate itself and spread.

A prevention trial is underway to see if cabotegravir injections, every eight weeks, can lower infection rates among people at high risk of HIV. Other trials are testing the drug for maintaining HIV suppression in people who've gotten the virus down to very low levels with standard medication; there it's given in monthly injections along with another drug, called rilpivirine.

The idea is to free people from needing daily pills.

Oral medications for HIV, which came to market in the 1990s, have changed the face of the epidemic. They are no cure, but when people can stick with their medication regimen, the virus can be suppressed for years.

"The main challenge we face today is adherence," said Dr. Melanie Thompson, former chairwoman of the HIV Medicine Association.

Taking pills every day, for life, is "not so easy," noted Thompson, who was not involved in the new study. People can simply forget, she said, or fail to bring their medication on a trip. They can also run out of pills, or have trouble paying for them.

Longer-acting medications could be helpful in that regard. On the other hand, Thompson said, safety becomes an even bigger concern if a drug is going to persist in the body for a long time.

"If you take it and you don't do well, you're stuck with it," she said. "You can't take it away."

Another question, Thompson said, is what happens toward the end of the drug's life in the body. Does it suddenly shut off? Or do levels of the drug wane to where they would no longer be protective, but possibly allow the virus to develop resistance to it?

The safety concerns also include possible drug interactions: What if someone on a long-acting drug develops an infection and needs medication? Or, Thompson said, what if she becomes pregnant?

With a yearly formulation, instead of every two months, those issues loom even larger.

"The idea of moving toward something that's given once a year is exciting," Thompson said. But, she stressed, many unknowns would have to be addressed.

Gendelman said that while the cabotegravir injections currently in trials could free people from daily pills, they would still require frequent doctor visits -- and a regular jab into the buttocks muscle, which can be uncomfortable for days.

That's what led him and colleague Benson Edagwa, an assistant professor, to the current project.

Edagwa, a chemist, designed the modifications necessary to turn cabotegravir into a "nanocrystal." After it's injected, much of that modified substance takes up residence in muscle, some of it in the liver and spleen, Gendelman said. Over time, the body's own enzymes "very slowly" convert it into active drug.

At least that's what happens in lab mice and rhesus macaque monkeys. Results in humans are often different than in animals.

And Thompson said more animal research is needed to evaluate safety. The results of the ongoing prevention trial, where cabotegravir is being given every eight weeks, should be informative, she said.

If a once-a-year version were ever to be used for HIV treatment, it would have to be paired with another long-acting medication -- since, Thompson noted, HIV is never treated with a single drug.

More information

The U.S. Department of Health and Human Services has more on HIV treatment.

SOURCES: Howard Gendelman, M.D., chairman, department of pharmacology and experimental neuroscience, University of Nebraska Medical Center, Omaha; Melanie Thompson, M.D., former chairwoman, HIV Medicine Association, Arlington, Va.; April 27, 2020, Nature Materials, online

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Researchers Move Toward Once-Yearly Treatment for HIV - HealthDay

Neuroscience

Fenves and Johnston: Kirk Watson Transformed Health and Health Care in Austin – The Alcalde

ByGregory L. Fenves and Clay Johnston in 40 Acres on April 30, 2020 at 11:28 am |

Dear Senator Watson,

In your final week as a Texas state senator, we have been reflecting on the extraordinary impact you have had on our community and your special legacy in shaping the health care mission of The University of Texas at Austin.

In the early 2000s, there was much talk of building a medical school in Austin. It was an ambition that had been discussed for decades but had never materialized. A medical school in one of the largest cities without one felt like an idea that would be perpetually pushed to the future for a later generation to take on.

But in 2011, you changed everything. Your 10 Goals in 10 Years for Health Care lit the fire. Immediately, the pathway forward for our city and county was illuminated.

The No. 1 goal on your 10 in 10 list was to build a medical school. This was your priority because you understood the tremendous talent and resources available at our university. You knew that UT Austin had the ability to build a medical school like no other and train generations of doctors who could serve our city, county, state and nation. So, you did what you do best brought people together to make it happen.

You made sure that a broad coalition worked collaboratively on a shared vision for health in Texas. You helped people see health care as a fundamental issue that affects everyone regardless of background, beliefs or politics. And you made your case for change by telling your personal story as a cancer survivor, and people responded. Nobody else could have done that.

It all came together in 2012, when Travis County voters in an unprecedented move approved a ballot measure to invest in the creation of a new medical school. That commitment launched the Dell Medical School. And with strong support from the UT System Board of Regents, the Michael & Susan Dell Foundation and so many others in our Longhorn community, Dell Med welcomed its first class of 50 students in 2016.

And here we are now, nearly four years later, with Dell Meds inaugural class preparing to graduate next month.

Senator Watson, you made it possible for Dell Meds nearly 200 students to receive a world-class medical education right here in our states capital. And now, the first graduates are going to pay it forward all have matched with residency programs across the country and almost half of them will remain in Texas (11 will stay right here in Austin) to practice medicine and serve at a time when they are needed to help lead us through an unprecedented public health crisis.

And your impact on the universitys health care mission goes beyond our students and future doctors: UT Health Austins medical workers have been on the front lines of the COVID-19 crisis and are delivering patient-centered, value-focused care to our community; our unique partnerships with Central Health and Ascension Seton are further elevating the level of care in Austin; in 2014, the Livestrong Cancer Institutes emerged to pioneer new approaches to cancer treatment and care; in 2016, the Mulva Clinic for the Neurosciences took shape to advance patient treatment and neuroscience research; and just last year, your tireless work helped to prioritize the mental health needs of patients and families at the Austin State Hospital, which is now poised to become a premier center of brain health.

There is an old saying: Education is not the filling of a pail, but the lighting of a fire. You were the leader who lit the fire that sparked a health care revolution that started on our campus and is growing across Central Texas. Generations of Texans will benefit from all you have done.

You may be a University of Houston Cougar now, but forever in our community, you will be known as a Longhorn. Thank you, Senator Watson. We are deeply grateful.

Gregory L. Fenves is President of The University of Texas at Austin.

S. Claiborne Clay Johnston is dean of the Dell Medical School at The University of Texas at Austin.

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Fenves and Johnston: Kirk Watson Transformed Health and Health Care in Austin - The Alcalde

Neuroscience

Spinal Cord Injuries: UVA Scientists Probe Individual Cells to Find Better Treatments – University of Virginia

Two top scientists at theUniversity of Virginia School of Medicineare seeking answers to questions about spinal cord injuries that have long frustrated the development of effective treatments.

The scientists, Jonathan Kipnis and Kodi Ravichandran, are teaming up to understand why critical nerve cells called neurons continue to die after spinal cord injuries. So little is known that doctors arent even certain if the bodys immune response is beneficial or harmful.

By understanding that process, Kipnis and Ravichandran hope to pave the way for more effective treatments, either by enhancing or limiting the immune response. Their work has received $350,000 in backing from the philanthropicChan Zuckerberg Initiative.

Bringing someone of Ravis caliber, who is a world expert in phagocytic clearance, to study questions related to brain and spinal cord injuries is exactly what this CZI initiative is about, said Kipnis, chair of UVAs Department of Neuroscience and director of UVAs Brain Immunology and Glia Center, or BIG. Merging complementary expertise and focusing on one common goal could lead to a real scientific breakthrough.

The researchers aim to understand what happens after spinal cord injury at the level of individual cells. Theyll do this using a new probe developed by Ravichandran that causes dying cells to glow under the microscope. He and Kipnis will be able to track the dead cells as they are swallowed up by immune cells, called phagocytes, that remove them from the body.

This will provide important insights into how the body responds to spinal cord injury. For example, the researchers will seek to determine if neurons are dying because immune cells called microglia arent up to the task of removing harmful debris. Or if other immune cells, called macrophages, cant get to where theyre needed.

By determining what types of cells are involved in the injury response, and exactly what those cells are doing, the researchers will identify potential avenues to improve the treatment of spinal cord injuries.

Knowing what cell type is the phagocyte at the site of damage would allow us to specifically target that cell type or subtype of cells to eat more of the cellular debris after the brain or spinal cord injury, explained Ravichandran, chair of the Department of Microbiology, Immunology and Cancer Biology. Plus, via these single-cell analyses, we will also learn how the genetic program of the cleaning crew changes at the injury site over time, and this would help us to mold the response toward better tissue repair.

Ravichandran said he is excited by the opportunity to explore new territory.This is a fun collaboration because Jony is highly creative, and we get to take approaches and pursue a topic that each of us may not have normally done on our own, he said.

The financial backing from theChan Zuckerberg Initiative is part of $14 million in funding the group is awarding to 29 interdisciplinary teams to explore the role of inflammation in disease.

Knowing more about inflammation at the level of affected cells and tissues will increase our understanding of many diseases and improve our ability to cure, prevent or manage them, said CZI Head of Science Cori Bargmann. We look forward to collaborating with these interdisciplinary teams of researchers studying inflammation.

To learn more, visithttps://chanzuckerberg.com/newsroom/14-million-support-inflammation-research/.

A full list of funding recipients is available athttps://chanzuckerberg.com/science/programs-resources/single-cell-biology/inflammation-projects/.

To keep up with the latest medical research news from UVA, subscribe to theMaking of Medicineblog.

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Spinal Cord Injuries: UVA Scientists Probe Individual Cells to Find Better Treatments - University of Virginia

Neuroscience

Forward-Looking Approach of BJ Klock, the CEO of Advisight – The Ritz Herald

Advisight, award-winning Market Research Centre, providing services from over a decade with professional expertise in Media Research, Neurosciences, Data Insights leading Strategy, and so many more is organizing an Influencer-Con Event which will definitely change your perspective towards Branding & Marketing and stimulate your business acumen.

With a network of over 650 million people, Advisight is expert in lifting their members KPIs by employing cutting edge technology.

There is a saying that A brand is no longer what we tell the consumer it is it is what consumers tell each other it is. With that in mind, Advisight attracts loyal fans with their revolutionary Neuroscience research which creates a ubiquitous brand. Their key motto behind all these scientific ways of projecting brands is to inspire people to live their dreams, create opportunities that generate yield for everyone, and have a constructive impact holistically.

Within a few years, Advisight scored quite a numerous award which underscores their recognition to target markets attention nationally and internationally with an effective and efficient way, to name a few:

The CEO of Advisight, BJ Klock who is the topmost growth hacker on the pyramid of branding and marketing strategies is considered one of the best entrepreneurs in the world. He has the honor to share his expertise and knowledge with some of the famous brands, billionaires, and celebrities. Bj was also featured as an Expert Contributor for Success in Huffington Post & Forbes. Aside from running Advisight, BJ is an advisor with The Oracles & elite member of METal International

In an interview with BJ, the nucleus of his thinking was that we should consider future developments when making plans, especially when you want to see your brand on the next level.

His forward-looking approach towards Brand Amplification, Advertising & Marketing is crystal clear which helps him extending the following services to his valued clients:

Advisight has also created a fund called Advisight Research Fund. The main goal of this activity is to fund the research of the worlds most sought-after answers.

Influence-Con will be taking place on Saturday, September 26, 2020, interested brands can visit their website to secure a VIP pass as General category is already sold out.

Alternatively, feel free to reach out to them over phone 1-833-800-GROW (4769) or visit their website.

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Forward-Looking Approach of BJ Klock, the CEO of Advisight - The Ritz Herald

Neuroscience

Global Neuroscience Antibodies and Assays Market (2020 to 2024) – Key Players Include Abcam, Bio-Rad Laboratories & Cell Signaling Technology…

DUBLIN--(BUSINESS WIRE)--The "Global Neuroscience Antibodies and Assays Market 2020-2024" report has been added to ResearchAndMarkets.com's offering.

The author has been monitoring the global neuroscience antibodies and assays market and it is poised to grow by USD 1.36 bn during 2020-2024, progressing at a CAGR of 8% during the forecast period. The reports on global neuroscience antibodies and assays market provides a holistic analysis, market size and forecast, trends, growth drivers, and challenges, as well as vendor analysis covering around 25 vendors.

The report offers an up-to-date analysis regarding the current global market scenario, latest trends and drivers, and the overall market environment. The market is driven by technological advances. In addition, advances in neuroscience instruments is anticipated to boost the growth of the global neuroscience antibodies and assays market as well.

This study identifies advances in neuroscience instruments as the prime reasons driving the global neuroscience antibodies and assays market growth during the next few years.

Companies Mentioned

Key Topics Covered:

1. EXECUTIVE SUMMARY

2. SCOPE OF THE REPORT

3. MARKET LANDSCAPE

4. MARKET SIZING

5. FIVE FORCES ANALYSIS

6. MARKET SEGMENTATION BY PRODUCT

7. CUSTOMER LANDSCAPE

8. GEOGRAPHIC LANDSCAPE

9. DRIVERS AND CHALLENGES

10. MARKET TRENDS

11. VENDOR LANDSCAPE

12. VENDOR ANALYSIS

13. APPENDIX

For more information about this report visit https://www.researchandmarkets.com/r/n0dh3w

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Global Neuroscience Antibodies and Assays Market (2020 to 2024) - Key Players Include Abcam, Bio-Rad Laboratories & Cell Signaling Technology...