Category Archives: Neuroscience

Neuroscientists find a way to make object-recognition models perform better – MIT News

Computer vision models known as convolutional neural networks can be trained to recognize objects nearly as accurately as humans do. However, these models have one significant flaw: Very small changes to an image, which would be nearly imperceptible to a human viewer, can trick them into making egregious errors such as classifying a cat as a tree.

A team of neuroscientists from MIT, Harvard University, and IBM have developed a way to alleviate this vulnerability, by adding to these models a new layer that is designed to mimic the earliest stage of the brains visual processing system. In a new study, they showed that this layer greatly improved the models robustness against this type of mistake.

Just by making the models more similar to the brains primary visual cortex, in this single stage of processing, we see quite significant improvements in robustness across many different types of perturbations and corruptions, says Tiago Marques, an MIT postdoc and one of the lead authors of the study.

Convolutional neural networks are often used in artificial intelligence applications such as self-driving cars, automated assembly lines, and medical diagnostics. Harvard graduate student Joel Dapello, who is also a lead author of the study, adds that implementing our new approach could potentially make these systems less prone to error and more aligned with human vision.

Good scientific hypotheses of how the brains visual system works should, by definition, match the brain in both its internal neural patterns and its remarkable robustness. This study shows that achieving those scientific gains directly leads to engineering and application gains, says James DiCarlo, the head of MITs Department of Brain and Cognitive Sciences, an investigator in the Center for Brains, Minds, and Machines and the McGovern Institute for Brain Research, and the senior author of the study.

The study, which is being presented at the NeurIPS conference this month, is also co-authored by MIT graduate student Martin Schrimpf, MIT visiting student Franziska Geiger, and MIT-IBM Watson AI Lab Co-director David Cox.

Mimicking the brain

Recognizing objects is one of the visual systems primary functions. In just a small fraction of a second, visual information flows through the ventral visual stream to the brains inferior temporal cortex, where neurons contain information needed to classify objects. At each stage in the ventral stream, the brain performs different types of processing. The very first stage in the ventral stream, V1, is one of the most well-characterized parts of the brain and contains neurons that respond to simple visual features such as edges.

Its thought that V1 detects local edges or contours of objects, and textures, and does some type of segmentation of the images at a very small scale. Then that information is later used to identify the shape and texture of objects downstream, Marques says. The visual system is built in this hierarchical way, where in early stages neurons respond to local features such as small, elongated edges.

For many years, researchers have been trying to build computer models that can identify objects as well as the human visual system. Todays leading computer vision systems are already loosely guided by our current knowledge of the brains visual processing. However, neuroscientists still dont know enough about how the entire ventral visual stream is connected to build a model that precisely mimics it, so they borrow techniques from the field of machine learning to train convolutional neural networks on a specific set of tasks. Using this process, a model can learn to identify objects after being trained on millions of images.

Many of these convolutional networks perform very well, but in most cases, researchers dont know exactly how the network is solving the object-recognition task. In 2013, researchers from DiCarlos lab showed that some of these neural networks could not only accurately identify objects, but they could also predict how neurons in the primate brain would respond to the same objects much better than existing alternative models. However, these neural networks are still not able to perfectly predict responses along the ventral visual stream, particularly at the earliest stages of object recognition, such as V1.

These models are also vulnerable to so-called adversarial attacks. This means that small changes to an image, such as changing the colors of a few pixels, can lead the model to completely confuse an object for something different a type of mistake that a human viewer would not make.

As a first step in their study, the researchers analyzed the performance of 30 of these models and found that models whose internal responses better matched the brains V1 responses were also less vulnerable to adversarial attacks. That is, having a more brain-like V1 seemed to make the model more robust. To further test and take advantage of that idea, the researchers decided to create their own model of V1, based on existing neuroscientific models, and place it at the front of convolutional neural networks that had already been developed to perform object recognition.

When the researchers added their V1 layer, which is also implemented as a convolutional neural network, to three of these models, they found that these models became about four times more resistant to making mistakes on images perturbed by adversarial attacks. The models were also less vulnerable to misidentifying objects that were blurred or distorted due to other corruptions.

Adversarial attacks are a big, open problem for the practical deployment of deep neural networks. The fact that adding neuroscience-inspired elements can improve robustness substantially suggests that there is still a lot that AI can learn from neuroscience, and vice versa, Cox says.

Better defense

Currently, the best defense against adversarial attacks is a computationally expensive process of training models to recognize the altered images. One advantage of the new V1-based model is that it doesnt require any additional training. It is also better able to handle a wide range of distortions, beyond adversarial attacks.

The researchers are now trying to identify the key features of their V1 model that allows it to do a better job resisting adversarial attacks, which could help them to make future models even more robust. It could also help them learn more about how the human brain is able to recognize objects.

One big advantage of the model is that we can map components of the model to particular neuronal populations in the brain, Dapello says. We can use this as a tool for novel neuroscientific discoveries, and also continue developing this model to improve its performance under this challenging task.

The research was funded by the PhRMA Foundation Postdoctoral Fellowship in Informatics, the Semiconductor Research Corporation, DARPA, the MIT Shoemaker Fellowship, the U.S. Office of Naval Research, the Simons Foundation, and the MIT-IBM Watson AI Lab.

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Neuroscientists find a way to make object-recognition models perform better - MIT News

Neuroscience Antibodies and Assays Market 2027 In-Depth Coverage And Various Important Aspects – Cheshire Media

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Table of Content of the Report

Executive Summary

Assumptions and Acronyms Used

Research Methodology

Neuroscience Antibodies and Assays Market Overview

Global Neuroscience Antibodies and Assays Market Analysis and Forecast by Type

Global Neuroscience Antibodies and Assays Market Analysis and Forecast by Application

Global Neuroscience Antibodies and Assays Market Analysis and Forecast by Sales Channel

Global Neuroscience Antibodies and Assays Market Analysis and Forecast by Region

North America Neuroscience Antibodies and Assays Market Analysis and Forecast

Latin America Neuroscience Antibodies and Assays Market Analysis and Forecast

Europe Neuroscience Antibodies and Assays Market Analysis and Forecast

Asia Pacific Neuroscience Antibodies and Assays Market Analysis and Forecast

Asia Pacific Neuroscience Antibodies and Assays Market Size and Volume Forecast by Application

Middle East & Africa Neuroscience Antibodies and Assays Market Analysis and Forecast

Competition Landscape

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Neuroscience Antibodies and Assays Market 2027 In-Depth Coverage And Various Important Aspects - Cheshire Media

Making Connections: Psychologist explores the neuroscience of creativity – Penn State News

Is there anything more mysterious or human than the creative impulse? Whatever the field of endeavor: music, art, science, business What accounts for the inspired burst of innovation? The spark that flits to flame and lights the way to something entirely new?

Roger Beaty became interested in this question as an undergraduate, in a class that explored the psychology of genius. An amateur jazz pianist, he was already well-versed in improvisation. But this was the first time I realized that you could study creativity scientifically, he remembers. Combing through case studies of Picasso and the Beatles, following in their gigantic footprints, was a way toward understanding why some people are more creative than others.

Roger Beaty, anamateur jazz pianist, plays a Miles Davis piece on the keyboard in his lab.

There are several cognitive processes involved. Memory is a crucial one, says Beaty, now an assistant professor of psychology at Penn State.

Memory is what we already know. Creativity involves going beyond what we know but if we dont know anything, we cant create anything new," said Beaty.

Whats really relevant, he said, is the organization of memory, how a persons brain catalogs disparate concepts and experiences in order to facilitate making connections. Its an ability that varies between individuals.

Also important is the ability to focus, to narrow ones attention to the task at hand. But focus needs to be balanced with spontaneity, Beaty said. Creative people tend to be open to experience, to seeing things in new ways.

These processes and others all have their roles to play. But how much does each contribute to an individuals creativity? Is there something noticeably different going on inside the head of an innovator? How does creativity happen in the brain?

Wired differently

The neuroscience of creativity is an emerging field that has attracted researchers from several disciplines, but it can seem an odd combination. How do you fix a thing as ephemeral as creativity? How pin the butterfly of a new idea to the realm of neurons and physiology?

First, Beaty said, you have to agree on a definition. Researchers in the field generally accept that in order to be considered creative, an idea must be both new and useful.

Pure novelty is not enough, he said, even if usefulness in a domain like abstract art is not so clear cut. Creativity is essentially the solving of a problem, even if its a problem that no one knew existed.

This small sampling from thousands of drawings shows a range of responses to a creativity test administered in psychologist Roger Beatys lab. Participants given a prompt were asked to complete the drawing with whatever came to mind.

A participant's response to a creativity test administered in psychologist Roger Beatys lab. Participants given a prompt were asked to complete the drawing with whatever came to mind.

IMAGE: courtesy Roger Beaty

As part of a creativity test administered in psychologist Roger Beatys lab, participants were given this prompt and asked to complete the drawing with whatever came to mind.

IMAGE: courtesy Roger Beaty

A participant's response to a creativity test administered in psychologist Roger Beatys lab. Participants given a prompt were asked to complete the drawing with whatever came to mind.

IMAGE: courtesy Roger Beaty

A participant's response to a creativity test administered in psychologist Roger Beatys lab. Participants given a prompt were asked to complete the drawing with whatever came to mind.

IMAGE: courtesy Roger Beaty

A participant's response to a creativity test administered in psychologist Roger Beatys lab. Participants given a prompt were asked to complete the drawing with whatever came to mind.

IMAGE: courtesy Roger Beaty

A participant's response to a creativity test administered in psychologist Roger Beatys lab. Participants given a prompt were asked to complete the drawing with whatever came to mind.

IMAGE: courtesy Roger Beaty

A participant's response to a creativity test administered in psychologist Roger Beatys lab. Participants given a prompt were asked to complete the drawing with whatever came to mind.

IMAGE: courtesy Roger Beaty

A participant's response to a creativity test administered in psychologist Roger Beatys lab. Participants given a prompt were asked to complete the drawing with whatever came to mind.

IMAGE: courtesy Roger Beaty

To measure creativity in individuals, researchers employ various tests. One requires giving a study participant pairs of randomly-selected words shoe and door, say, or rowboat and parrot and asking them to rate how closely these words are related to one another.

People who are more creative are able to see connections between things that might seem unrelated, Beaty explained.

Another test of divergent thinking asks participants to find new uses for common objects, like a sock or a brick. One creative person, Beaty reported, suggested using a sock as a water-filtration system.

Things start to get really interesting when people perform these tasks while researchers observe their brain activity via a functional MRI scan, which provides a real-time image of blood flow to various parts of the brain.

In a study published in theProceedings of the National Academy of Sciences (PNAS) in 2018, Beaty and colleagues asked 163 people to complete an alternate uses task while in the scanner. Noting the areas that were lighting up in participants brains, indicating activity, they computed the linkages between these regions. Thus for each individual they were able to create a map of connectivity that could be related to performance of the task at hand essentially a map of creative thinking.

This next step was even more revealing. The researchers put the brain-connectivity patterns of the people whose answers on the test were deemed most creative into a computer model, then brought in a fresh set of participants to take the test. Just from comparing a new persons connectivity patterns with the model, they found, they could predict what that individuals creativity score would be.

Detail from a figure in Roger Beaty's PNAS paper shows functional brain networks associated with high-creative thinking ability.The red lines on the brain represent connections predictive of creativity scores and the dots represent brain regions: the larger the dot, the more predictive connections. Regions of the default,executivecontrol, and salience networks are indicated within this larger network by the larger dots.The strengthof connections between these three regions predicted people's ability to think of creative uses for test objects.

IMAGE: courtesy Roger Beaty

Ultimately, Beaty said, the study pinpointed three primary networks in the brain that are involved in creative thinking. The first, called the default network, is the area that activates when a person is relaxing, daydreaming, thinking of nothing in particular.

Its the place for spontaneous ideas, said Beaty. Its also strongly related to memory.

The second network is defaults opposite, the executive control network.Its involved in focusing our attention to accomplish challenging tasks, he said.

The thing about these two networks is they typically dont work together, he added. If your mind is wandering you dont need focused attention, and when youre focusing you dont want spontaneous thoughts slipping in. Its kind of an antagonistic relationship.

For creativity to happen, however, the two have to learn to get along. Its the interplay between them, in fact, that makes the magic: an iterative process between idea generation and evaluation. Thats where a third player, the salience network, comes in, acting as a kind of toggle between them.

All three of these networks, Beaty said, become active during a creative task. The degree of a persons creativity depends on the strength of connections between them.

Can creativity be taught?

Its tempting to conclude that creative peoples brains are simply wired differently. The question then becomes: Is that wiring fixed forever? Might it be changeable? Can a persons creativity be improved? Once thePNASstudy was published, Beaty said, That was the first thing people wanted to know.

The popularity of creativity workshops for business leaders and aspiring artists would seem to suggest that creative potential can be developed, or at least unlocked. But can those brain connections actually be strengthened? Its an open question, and one that Beaty and his colleagues now have NSF funding to try to answer.

Is scientific creativity different from the artistic kind? Are there separate flavors of creativity?

The context for their new study is STEM education. In particular, the researchers will look at whether scientific creativity can be fostered in college students. Their plan is to scan the brains of incoming first-year students, then scan again at intervals after participants have had training in STEM fields, checking to see if connections are strengthened over time. But first we have to come up with a good test of scientific creativity, Beatty said.

Which raises another question: Is scientific creativity different from the artistic kind? Is either of these distinct from garden-variety problem-solving? Are there separate flavors of creativity?

There are some general traits that seem to be shared, Beaty said. Flexibility of thinking, the ability to make connections, including the ability to draw analogies, a subject he investigated as a graduate student. Then you have to have the domain-specific training, the 10,000 hours people talk about. Alas, mastery of a subject, while a prerequisite for creativity, is no guarantee.

A test of specifically scientific creativity, he suggests, might include things like hypothesis generation.

The ability to come up with good research questions, experimental design," said Beaty. "The sorts of thing Id like to be better at myself, honestly.

Once he and his colleagues have a test they are happy with, and if they do see connectivity changes over time, the researchers plan to turn their focus to ways of enhancing scientific creativity in K-12 classrooms.

Humans and machines

Its an ambitious program, given the challenges built into studying something so elusive.

One problem is the sheer awkwardness of trying to capture the creative process: Lying in a thrumming MRI machine is not very conducive to writing poetry or composing music. To get around this, Beaty and other researchers have rigged up keyboards and drawing pads with non-metal components to make them MRI-compatible. Even with these enhancements, he acknowledges, creativity doesnt always happen on demand.

An MRI-compatible drawing pad and stylus allow participants to create pictures while their brains are being scanned to reveal regions of activity.

Theres also the difficulty of proving causality. The connectivity patterns were studying are correlated but we dont know if there is causality, Beaty explained. Combining fMRI with a technique called transcranial electrical stimulation may help with this: By stimulating the brain with very mild currents through the scalp, he and his team may be able to directly induce increased neuron activity in specific brain regions, then measure the effects on performance.

Yet another challenge is the subjectivity of human testers assigning scores for creativity. Its not like determining whether someone got a correct answer on a memory test, Beaty said. People vary quite a bit in what they think is creative.

Training helps to standardize scoring. But Beaty also relies on machine-learning methods like latent semantic analysis, an algorithm that finds word-use patterns in blocks of text and assigns probability to the occurrence of unusual pairings. It turns out fortunately that the values you get from these text analyses correlate fairly well with human readings, he said.

In fact, machine learning and artificial intelligence are making rapid inroads in the science of creativity, he added. Some of his colleagues are working on co-creative agents, computer programs that work with human partners to come up with new ideas. Others study generative adversarial networks, or GANs, that pit powerful clusters of computers known as neural networks against one another, mimicking the creative back-and-forth of idea generation and evaluation. Just last year, a pair of GANs produced a painting that so successfully imitated the work of an Old Master it was deemed indistinguishable, and sold at auction for half a million dollars.

Is this, then, the future for this quintessentially human quality? Will we one day be outsourcing the mystery of creativity to machines?

Thats a question thats not really settled yet, Beaty said with the hint of a smile. But I think theres more time for us before we completely throw in the towel.

The rest is here:
Making Connections: Psychologist explores the neuroscience of creativity - Penn State News

Has Neuroscience Proved That the Mind Is Just the Brain? – Walter Bradley Center for Natural and Artificial Intelligence

Last month, materialist neurologist Steven Novella made a rather astonishing claim in a post at his Neurologica blog: A recent open-access study of learning and decision-making in mice shows that the human mind is merely what the human brain does. Thats a lot for mice to prove.

In the study, the mice were trained to choose holes from which food is provided. Their brain activity was measured as they learned and decided which holes were best. The research looks specifically at quick and intuitive decision-making vs. decision-making that is slower and involves analysis of the situation. The investigators found that analysis-based decisions in the mice involve brain activity in the anterior cingulate cortex, which is a region of the brain in the fissure between the hemispheres.

From the standpoint of understanding the mind-brain relationship, this study is unremarkable. There is no doubt that thinking usually involves brain activity of some sort. Dualists (who think that the human mind uses the brain but is not identical with it) and materialists (who think that the mind is just what the brain does) have no disagreement here. This study details the correlative brain activity in mice, which is nice to know. But Dr. Novella takes this mundane study and draws a ludicrous conclusion:

I also feel obligated to point out that research like this completely destroys any notion of dualism that mental function exists somehow outside of or separate from the biological functioning of the brain. So far, the neuroscience hypothesis, that mental function is brain function, is working quite well. The brain is a complex biological computer, and we can figure out how it works by studying it. Even the most sophisticated cognitive processes, such as analytical decision-making, are demonstrably happening in the brain. Further, not only is there zero evidence for the dualist hypothesis, it is completely unnecessary, which is a fate in science even worse than being wrong.

Nonsense. Novella has been trying to sell his materialist ideology in the guise of neuroscience for more than a decade. This is only the most recent in a host of his bizarre claims, including his 2008 assertion that The materialist hypothesis that the brain causes consciousnesshas made a number of predictions, and every single prediction has been validated.

Thats a beautiful example of the Dunning-Kruger effect (people overestimate their mastery of a situation they dont understand.) In neuroscience, materialism is the answer only if you dont understand the questions. Here are some of them:

First, the philosophical issues. Its fair to say that the mind-brain problem is the most active and contentious field of philosophical inquiry in modern times. Philosopher David Chalmers has summarized the conundrum succinctly: there are two kinds of problems in understanding how the mind relates to the brain: the easy problems and the hard problem.

The easy problems are the ordinary scientific questions addressed by neuroscience, such as What part of the brain is active when I think? or What neurotransmitters are secreted when I feel anxious? The science may be difficult but the questions are tractable. Scientific research has the tools to address these easy problems.

The hard problem is another matter entirely: How do material brain states correspond to mental states? How could a certain concentration of chemicals in my brain cause me to do calculus? How could a specific electrochemical gradient in my brain make me feel sad? What is the link?

The answer, says Chalmers, is that we have no idea how brain states can cause thoughts. There is certainly no explanation provided by sciencethere is no mathematical formula that links neurons to thoughts and there is no reason to think there ever will be or ever can be. Brains are material, thoughts are immaterial, and there is no way imaginable to explain one by the other. This is why the hard problem (Chalmers himself coined the term in 1995) is hardits not even tractable by neuroscience, let alone solvable.

Other philosophers have used different terms for the hard problemJoseph Levine calls it the Explanatory Gap. But the problem is the same. There is no explanation for the mental on the basis of the physical. No physics or chemistry explains thought.

What is not in doubt is that, to some extent, thoughts correlate with brain activity. On that, dualists and materialists agree. But what is also not in doubt is that there is no materialist explanationand there cannot be a materialist explanation for the mind.

There are two general non-materialist ways of understanding the mind-brain relationship. Theres idealism, according to which, reality itself is a form of thought and human thought participates in it. That is a profound metaphysical perspective that offers much to admire both as a theory of mind and as a metaphysical basis for science, although in modern times it is (regrettably) not in vogue.

Alternatively, there are various kinds of dualismsubstance dualism, property dualism, Thomistic dualism to name a fewwhich offer coherent and scientifically consistent descriptions of the mind and brain. My own view is Thomistic dualism. But I acknowledge that idealism and other variants of dualism have undeniable strengths.

The neuroscience evidence for dualism is very strong. Many of the greatest neuroscientists of the past century have been dualists or idealists Charles Sherrington, Ramon y Cajal, Wilder Penfield, Benjamin Libet, Roger Sperry, and John Eccles, to name a few. The pioneering research of Wilder Penfield in neurosurgery for epilepsy strongly supported dualism. The research on the correlates between brain activity and will by Benjamin Libet supports a dualist interpretation of free will (Libet himself was a property dualist).

Roger Sperrys Nobel-prize winning research on split-brain patients clearly supports a non-materialist perspective. Sperry, whose philosophy I would describe as idealist, rejected the prevailing materialism common among neuroscientists:

[I rejected] the then prevalent mechanistic, materialistic, behavioristic, fatalistic, reductionistic view of the nature of mind and psyche. It was on this occasion that I openly changed my alignment from behaviorist materialism to antimechanistic and nonreductive mentalism

The emerging science of near-death experiences, as well as the evidence for mental activity even in the most profound states of coma, provide powerful evidence for the ability of the mind to function at least somewhat independently of the body. It can be argued that even the strong similarity between the ape brain and the human brain is evidence for dualism because the profound dissimilarity between the human mind and the ape mind cannot be readily explained on a material basis.

I offer a synopsis of the neuroscientific arguments for the immateriality of some kinds of thoughtabstract thought and free will here. But now, back to Steven Novella and the mice:

Dr. Novellas assertion that the study of brain activity in trained mice completely destroys any notion of dualism is abject nonsense. Novella gets the answers wrong because he doesnt understand the questions. Materialism is a woefully impoverished way to understand reality, and it is most clearly inadequate as a framework for neuroscience. To paraphrase philosopher Roger Scruton, Novellas materialist neuroscience is a vast collection of answers with no memory of the questions.

You may also enjoy these articles by Michael Egnor:

Why the mind cant just be the brain. Thinking it through carefully, the idea doesnt even make sense.

and

Is materialism falsifiable? Yes, easily. However, neurologist Steven Novella is sure that materialism is not falsifiable by science.

Read more:
Has Neuroscience Proved That the Mind Is Just the Brain? - Walter Bradley Center for Natural and Artificial Intelligence

Materialist Neurologist: ‘The Mind is Simply What the Brain is Doing – Science Times

Early last month, Steven Novella, a materialist neurologist, made a somewhat surprising claim in his Neurologica blog, "A recent open-access study of learning and decision-making in mice shows that the human mind is merely what the human brain does. That's a lot for mice to prove."

In this research, the mice were trained to choose holes where food is placed. The activity of mice's brains was gauged as they learned and decided which holes were best.

Furthermore, thestudylooked particularly at "quick and intuitive decision-making" against slower decision-making. It also involved an evaluation of the situation.

In this research, it was discovered that analysis-based decisions in the mice encompassed brain activity in the anterior cingulate cortex, a brain's region in the fissure between the hemispheres.

(Photo : Tibor Janosi Mozes on Pixabay)A recent open-access study of learning and decision-making in mice shows that the human mind is merely what the human brain does.

From the perspective of understanding the link between mind and brain, this research is said to be unremarkable. Undoubtedly, that perception usually engages activity of the brain of some sort.

Meanwhile, dualists, those who think that the mind of a human is using the brain but is not the same as it, and materialists, who think that the mind is simply what the brain is doing, do not have any disagreement here.

In this research is a detailed correlation of activity of the brain in mice may be nice to know. However, Novella is taking his so-called unremarkable study and drawing whatMind Matters Newsdescribed as an "absurd conclusion."

Such a conclusion specifies that Novella feels obliged to emphasize that research like this totally destroys the idea of 'dualism,' that mental function exists, one way or another, outside of or independent from the brain's biological function.

So far, the materialist neurologist explained, the 'neuroscience' hypothesis, "that mental function is brain function is working quite well."

The brain,Novella, continued explaining, is a multifaceted biological computer, and they could discover how it works by investigating it.

He also concluded that even the most sophisticated cognitive processes like analytical decision-making, for one, are evidently occurring in the brain.

Moreover, aside from having zero-evidence for what the study describes as a dualist hypothesis, it is entirely unimportant, which is "a fate in science even worse than being wrong."

Novella has been attempting to sell his materialist ideology in the appearance of neuroscience for over 10 years now.

This study is just the most recent in a series of his unusual claims, which includes his claim in 2008 that the "materialist hypothesis, the brain causes consciousness," has made numerous predictions, and every single forecast has been verified.

That is an ideal example of theDunning-Kruger effectwhere individuals overestimate their expertise in an occurrence they do not understand. Specifically, in neuroscience, materialist ideology is the answer, only if one does not understand the question.

Novella's claimthat the research of brain activity, particularly in trained mice, totally destroys any idea of dualism is said to be hopelessly nonsense.

As how materialist ideology is described, Novella is getting the answers wrong as he does not understand the questions.

More so, to Roger Scruton, a paraphrase philosopher, the materialist neuroscience of Novella is an extensive collection of answers without memory of the questions.

ALSO READ: Study Finds Spending Long Time on Mobile Phone is Not Harmful to Mental Health

Check out more news and information onBrain Functionon Science Times.

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Materialist Neurologist: 'The Mind is Simply What the Brain is Doing - Science Times

Global Neuroscience Antibodies and Assays Market Size, Comprehensive Analysis, Development Strategy, Future Plans and Industry Growth with High CAGR…

Global Neuroscience Antibodies and Assays Market Report, History and Forecast 2015-2026, Breakdown Data by Companies, Key Regions, Types and Application

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The global Neuroscience Antibodies and Assays Market report offers a complete overview of the Neuroscience Antibodies and Assays Market globally. It presents real data and statistics on the inclinations and improvements in global Neuroscience Antibodies and Assays Markets. It also highlights manufacturing, abilities & technologies, and unstable structure of the market. The global Neuroscience Antibodies and Assays Market report elaborates the crucial data along with all important insights related to the current market status.

The report additionally provides a pest analysis of all five along with the SWOT analysis for all companies profiled in the report. The report also consists of various company profiles and their key players; it also includes the competitive scenario, opportunities, and market of geographic regions. The regional outlook on the Neuroscience Antibodies and Assays market covers areas such as Europe, Asia, China, India, North America, and the rest of the globe.

Note In order to provide more accurate market forecast, all our reports will be updated before delivery by considering the impact of COVID-19.

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Top key players @ Thermo Fisher, Abcam, Bio-Rad, Merck, Cell Signaling Technology, Genscript, Rockland Immunochemicals, BioLegend, Santa Cruz Biotechnology, Roche, Siemens, and

The main goal for the dissemination of this information is to give a descriptive analysis of how the trends could potentially affect the upcoming future of Neuroscience Antibodies and Assays market during the forecast period. This markets competitive manufactures and the upcoming manufactures are studied with their detailed research. Revenue, production, price, market share of these players is mentioned with precise information.

Global Neuroscience Antibodies and Assays Market: Regional Segment Analysis

This report provides pinpoint analysis for changing competitive dynamics. It offers a forward-looking perspective on different factors driving or limiting market growth. It provides a five-year forecast assessed on the basis of how they Neuroscience Antibodies and Assays Market is predicted to grow. It helps in understanding the key product segments and their future and helps in making informed business decisions by having complete insights of market and by making in-depth analysis of market segments.

Key questions answered in the report include:

What will the market size and the growth rate be in 2026?

What are the key factors driving the Global Neuroscience Antibodies and Assays Market?

What are the key market trends impacting the growth of the Global Neuroscience Antibodies and Assays Market?

What are the challenges to market growth?

Who are the key vendors in the Global Neuroscience Antibodies and Assays Market?

What are the market opportunities and threats faced by the vendors in the Global Neuroscience Antibodies and Assays Market?

Trending factors influencing the market shares of the Americas, APAC, Europe, and MEA.

The report includes six parts, dealing with:

1.) Basic information;

2.) The Asia Neuroscience Antibodies and Assays Market;

3.) The North American Neuroscience Antibodies and Assays Market;

4.) The European Neuroscience Antibodies and Assays Market;

5.) Market entry and investment feasibility;

6.) The report conclusion.

Market Dynamics

The report analyzes the factors impacting the growth and the current market trends influencing the global Neuroscience Antibodies and Assays market. Detailed pricing information with ex-factory prices of various products by key manufacturers form a crucial part of the report. Competition analysis, along with regional government policies affecting the Neuroscience Antibodies and Assays market provides a detailed overview of the current status and prospects of the market. The impact of the ever-growing global population, coupled with technological advancements affecting the global Neuroscience Antibodies and Assays market is also covered in the report.

Drivers & Constraints

The report provides extensive information about the factors driving the global Neuroscience Antibodies and Assays market. Factors influencing the growth of the Neuroscience Antibodies and Assays market, along with technological advancements, are discussed extensively in the report. The current restraints of the market, limiting the growth and their future impact are also analyzed in the report. The report also discusses the impact of rising consumer demand, along with global economic growth on the Neuroscience Antibodies and Assays market.

Reasons for Buying this Report

This report provides pin-point analysis for changing competitive dynamics

It provides a forward looking perspective on different factors driving or restraining market growth

It provides a six-year forecast assessed on the basis of how the market is predicted to grow

It helps in understanding the key product segments and their future

It provides pin point analysis of changing competition dynamics and keeps you ahead of competitors

It helps in making informed business decisions by having complete insights of market and by making in-depth analysis of market segments

TABLE OF CONTENT:

1 Report Overview

2 Global Growth Trends

3 Market Share by Key Players

4 Breakdown Data by Type and Application

5 United States

6 Europe

7 China

8 Japan

9 Southeast Asia

10 India

11 Central & South America

12 International Players Profiles

13 Market Forecast 2019-2025

14 Analysts Viewpoints/Conclusions

15 Appendix

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Global Neuroscience Antibodies and Assays Market Size, Comprehensive Analysis, Development Strategy, Future Plans and Industry Growth with High CAGR...

Caltech Continues the 2020"2021 Watson Lectures with David J. Anderson, Seymour Benzer Professor of Biology – Broadway World

On Wednesday, December 9 at 5 p.m. Pacific Time, David J. Anderson, Caltech's Seymour Benzer Professor of Biology; the Tianqiao and Chrissy Chen Institute for Neuroscience Leadership Chair; director of the Tianqiao and Chrissy Chen Institute for Neuroscience; and a Howard Hughes Medical Institute Investigator, continues the 2020-2021 Watson Lecture season by exploring "The Inner Life of the Brain: Fear, Sex, and Violence."

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Caltech Continues the 2020"2021 Watson Lectures with David J. Anderson, Seymour Benzer Professor of Biology - Broadway World

Informative Report: What will be the future of the Global Neuroscience Antibodies & Assays Market – PharmiWeb.com

Pune, New York, USA, November 30 2020 (Wiredrelease) Research Dive :The global neuroscience antibodies & assays market is estimated to surpass $6,159.8 million by 2027, exhibiting a CAGR of 10.2% from 2020 to 2027.

The report aims to offer a clear picture of the current scenario and future growth of the global Neuroscience Antibodies & Assays Market market. The report provides scrupulous analysis of global market by thoroughly reviewing several factors of the market such as vital segments, regional market condition, market dynamics, investment suitability, and key players operating in the market. Besides, the report delivers sharp insights into present and forthcoming trends & developments in the global market.

The report articulates the key opportunities and factors propelling the global Neuroscience Antibodies & Assays Market market growth. Also, threats and limitations that have the possibility to hamper the market growth are outlined in the report. Further, Porters five forces analysis that explains the bargaining power of suppliers and consumers, competitive landscape, and development of substitutes in the market is also sketched in the report.

For More Detail Insights, Download Sample Copy of the Report at: https://www.researchdive.com/download-sample/1843

The report reveals various statistics such as predicted market size and forecast by analyzing the major factors and by assessing each segment of the global Neuroscience Antibodies & Assays Market market. Regional market analysis of these segments is also provided in the report. The report segments the global market into four main regions including Asia-Pacific, Europe, North America, and LAMEA. Moreover, these regions are sub-divided to offer an exhaustive landscape of the Neuroscience Antibodies & Assays Market market across key countries in respective regions. Furthermore, the report divulges some of the latest advances, trends, and upcoming opportunities in every region.

Furthermore, the report profiles top players active in the global Neuroscience Antibodies & Assays Market market. A comprehensive summary of 10 foremost players operating in the global market is delivered in the report to comprehend their position and footmark in the industry. The report highlights various data points such as short summary of the company, companys financial status and proceeds, chief company executives, key business strategies executed by company, initiatives undertaken & advanced developments by the company to thrust their position and grasp a significant position in the market.

RESEARCH METHODOLOGY

The research report is formed by collating different statistics and information concerning the Neuroscience Antibodies & Assays Market market. Long hours of deliberations and interviews have been performed with a group of investors and stakeholders, including upstream and downstream members. Primary research is the main part of the research efforts; however, it is reasonably supported by all-encompassing secondary research. Numerous product type literatures, company annual reports, market publications, and other such relevant documents of the leading market players have been studied, for better & broader understanding of market penetration. Furthermore, medical journals, trustworthy industry newsletters, government websites, and trade associations publications have also been evaluated for extracting vital industry insights.

Connect with Our Analyst to Contextualize Our Insights for Your Business:https://www.researchdive.com/connect-to-analyst/1843

KEY MARKET BENEFITS

This report is a compilation of qualitative assessment by industry analysts, detailed information & study, and valid inputs from industry participants & experts across the value chainAn in-depth analysis along with recent trends of the industry are provided in the report to identify & comprehend the prevailing opportunities and the tactical assessment of the global Neuroscience Antibodies & Assays Market market growthThe market size and forecasts are derived by scrutinizing market boomers and restraints, and key developments in the Neuroscience Antibodies & Assays Market marketThe report studies the market from 2019 to 2027 and maps the qualitative impact of several industry factors on market segments as well as geographiesThe development strategies implemented by the key industry players are conscripted in the report to understand the competitive scenario of the global Neuroscience Antibodies & Assays Market marketThe report also offers insights into foremost market players, Porters Five Analysis, and top winning business strategies

KEY MARKET SEGMENTS

The global Neuroscience Antibodies & Assays Market market is segmented on the basis of the following:

Global Neuroscience Antibodies & Assays Market Market By Product Type:

Consumables, Instruments

Global Neuroscience Antibodies & Assays Market Market By Applications:

Research, In Vitro Diagnostics, Drug Discovery and Development

Global Neuroscience Antibodies & Assays Market Market By Regions:

North America (U.S, Canada, and Mexico.)Europe (Germany, UK, France, Spain, Italy, Rest of Europe.)Asia-Pacific (Japan, China, India, Australia, South Korea, Rest of APAC.)LAMEA (Brazil, Argentina, Saudi Arabia, South Africa, UAE, Rest of LAMEA)

Top Leading key players stated in Global Neuroscience Antibodies & Assays Market Market report are:

Thermo Fisher Scientific, Abcam, Bio-Rad, Merck KGaA, BioLegend, Cell Signaling Technology, F. Hoffmann-La Roche, GenScript, Rockland Immunochemicals, Santa Cruz Biotechnology, Siemens, Tecan

The report also summarizes other important aspects including financial performance, product portfolio, SWOT analysis, and recent strategic moves and developments of the leading players.

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Informative Report: What will be the future of the Global Neuroscience Antibodies & Assays Market - PharmiWeb.com

MIT study shows how the brain is wired for reactive, reflexive movements – News-Medical.net

When riding your bike to the store you might have two very different reasons to steer: plain old reflex when something dart into your path, or executive control when you see street signs that indicate the correct route.

A new study by MIT neuroscientists shows how the brain is wired for both by tracking the specific circuits involved and their effect on visually cued actions.

The research, published in Nature Communications, demonstrates in mice that neurons in the anterior cingulate cortex (ACC) area of the prefrontal cortex, a region at the front of the brain associated with understanding rules and implementing plans, projects connections into an evolutionarily older region called the superior colliculus (SC).

The SC carries out basic commands reactive, reflexive key finding of the study is that the purpose of the ACC's connections to the SC is to override the SC when executive control is necessary.

The ACC provides inhibitory control of this ancient structure. This inhibitory control is a dynamic entity depending on the task and its rules. This is how a reflex is modulated by cortical control."

Mriganka Sur, Study Senior Author, Newton Professor of Neuroscience, Department of Brain and Cognitive Sciences at MIT, Picower Institute for Learning and Memory

Lead author Rafiq Huda, an assistant professor of cell biology and neuroscience at Rutgers University and a former postdoc in Sur's lab, added that by looking at specific circuits between the ACC and both the SC and the visual cortex (VC), the researchers could resolve uncertainty about how the cortex regulates more basic brain regions during decision-making.

"There has been an ongoing debate about what exactly is the role of the cortex in sensorimotor decisions," Huda said. "We were able to provide some answers by looking at the level of different ACC projection pathways, which would not have been possible by looking at all of ACC at once. Our work provides evidence for the possibility that inhibitory control of subcortical structures like the SC is a unifying principle for how the ACC, and the prefrontal cortex generally, modulates decision-making behavior."

To make their findings, the team first traced circuits going into and out of the ACC from both the VC and the SC, confirming that the ACC was in a prime position to integrate and process information about what the mice saw and what to do about it. Throughout the study, they chose to focus on these structures on the left side of the brain.

After tracing these left side ACC-SC and ACC-VC circuits, the team then trained mice to play a video game that required both sensation (seeing a cue on one side of the screen or the other) and action (spinning a trackball to move the cue).

One group of mice had to move the cue inward toward the screen's center. The other group had to move the cue outward toward the screen's edge. In this way, cues could be on either side visually and different groups of mice had to move them according to different rules.

As mice worked, the scientists observed the activity of neurons in the various regions to learn how they responded during each task. Then the researchers manipulated the neurons' activity using optogenetics, a technique in which cells are genetically engineered to become controllable by flashes of light.

These manipulations allowed the scientists to see how inhibiting neural activity within and between the regions would change behavior.

Under natural conditions, the SC would reflexively direct the movement of the mouse's head, for instance swiveling toward a stimulus to center it in view. But the scientists needed to keep the head still to make their observations, so they devised a way for mice to steer the stimulus on the screen with their paws on a trackball. In the paper, they show that these two actions are equivalent for mice to move a cue within their field of view.

Optogenetically inactivating the circuits between the ACC and VC on the brain's left side proved that the ACC-VC connection was essential for the mice to process cues on the right side of their field of view. This was equally true for both groups, regardless of which way they were supposed to move a cue when they saw it.

The manipulations involving the SC proved especially intriguing.

In the group of mice that saw a stimulus on the right and were supposed to move the cue inward to the screen's middle, when the scientists inactivated neurons within the left SC, they found that mice struggled compared to unmanipulated mice. In other words, under normal conditions, the left SC helped to move a stimulus on the right side into the middle of the field of view.

When the scientists instead inactivated input from the ACC to the SC, mice did the task correctly more often than unmanipulated mice. When the same mice saw a stimulus on the left and had to move it inwards, they did the task wrong more often.

The job of ACC inputs, it seemed, was to override the SC's inclination. When that override was disabled, the SC's preference for moving a righthand cue into the middle was unchecked. But the ability of the mouse to move a lefthand stimulus to the middle was undermined.

"Those results suggest that the SC and the ACC-SC pathway facilitate opposite actions," the authors wrote. "Importantly these findings also suggest that the ACC-SC pathway does so by modulating the innate response bias of the SC."

The scientists also tested the effect of ACC-SC inactivation in the second group of mice, whose job was to move the cue outward. There they saw that inactivation increased incorrect responses on right cue trials.

This result makes sense in the context of rules overriding reflex. If the reflex ingrained in the left-brain SC is to bring a righthand cue into the middle of the field of view (by swiveling the head right), then only a functioning ACC-SC override could compel it to successfully move the cue further to the right, and therefore further to the periphery of the field of view, when the task rule required it.

Sur said the findings accentuate the importance of the prefrontal cortex (in this case, specifically the ACC) in endowing mammals with the intelligence to follow rules rather than reflexes when needed. It also suggests that developmental deficits or injury in the ACC could contribute to psychiatric disorders.

"Understanding the role of the prefrontal cortex, or even a segment, is crucial to understanding how executive control can be developed, or may fail to develop, under conditions of dysfunction," Sur said.

Source:

Journal reference:

Huda, R., et al. (2020) Distinct prefrontal top-down circuits differentially modulate sensorimotor behavior. Nature Communications. doi.org/10.1038/s41467-020-19772-z.

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MIT study shows how the brain is wired for reactive, reflexive movements - News-Medical.net

What makes a prize-winning paper? Observations from the 2020 Brain Structure and Function Editors’ Choice Award – On Biology – BMC Blogs Network

Each year, Brain Structure and Function presents an Editors Choice Award in conjunction with the Cajal Club. The winning papers are selected by the journals editorial team, with the prize aiming to celebrate early career researchers and recognize their achievements as they progress in the field of neuroscience.

Ordinarily, these awards are presented as part of a ceremony during the Cajal Clubs annual social at the Society for Neuroscience meeting, one of the largest scientific conferences in the world. Proceedings may have moved online this year, but the award was still an excellent opportunity to showcase authors valued contributions to the journal.

The selection process for the Editors Choice Award is extremely competitive, and consists of multiple stages. Of 222 eligible publications from across 2019, Brain Structure and Functions Associate Editor team nominated a shortlist of 19 papers.

From the shortlist, four panel members each voted on their top picks, from which the winner and runner up emerged.

This years winning papers

The winner of this years award is Hong-Hsi Lee, for his article Along-axon diameter variation and axonal orientation dispersion revealed with 3D electron microscopy: implications for quantifying brain white matter microstructure with histology and diffusion MRI

Lee et al. figure the semi-automatic segmentation process for the inside of axons, as depicted in the winning article.

In this article, electron microscopy images showing the brains of mice are reconstructed. Previous modeling of neuronal tissue has relied on several assumptions about structure, for example that axons (long projections of nerve cells, or neurons) are perfectly cylindrical and even in diameter, or that the bundles of fibers within the axons are oriented consistently.

However, here an algorithm was developed and applied in order to rapidly segment individual constituents of axons, allowing for the calculation of several size-related parameters. While it was found that the distribution of the orientation of fibers within these axons remains stable along their length, the diameter of the axons varies. This means that in tissue microstructure modeling scenarios, an active area of research bridging the gap between the structure and function of the brain, axons should not be modeled as perfectly cylindrical.

At the time of this research being carried out, Hong-Hsi Lee was undertaking his PhD studies at New York University School of Medicine, advised by Els Fieremans and Dmitry S Novikov.

Now a Post-Doctoral Fellow at NYU, Hong-Hsis research projects continue to focus on the validation of biophysical models, analyzing numerical simulations in order to confirm or challenge various assumptions made in their design. Having developed a framework relevant to 3D cells organelles, he is now collaborating with Susie Y. Huang at Massachusetts General Hospital and Jeff W. Lichtman at Harvard University to extend this knowledge into human brain tissues, with promising preliminary results.

2020 winner Hong-Hsi Lee

Additionally, drawing on his statistical modeling skills and further expertise having completed an MD with the National Taiwan University, Dr Lee has undertaken an additional research project this year, looking at the collateral effects of measures against COVID-19 on common infections. His analysis of Taiwans National Health Insurance database showed that following the implementation of measures such as mask wearing and regular hand washing, rates of hospitalization due to other infections have been significantly decreased.

This years runner up prize for the Editors Choice Award went to Habon Issa, for her work as first author on an article comparing the brain microstructure of bonobo and chimpanzees, revealing differences in socio-emotional circuits.

Issa et al. figure a comparison of the proportion of neuropils (structural, connective elements of the brain) between Bonobos and Chimpanzees, alongside a microscopic image of the amygdala nuclei located in the brain)

While humans closest living relatives, chimpanzees and bonobos, are also closely related to each other, they show several important differences in behavior. Bonobos social tolerance is high, while chimpanzees are indicated to be more aggressive and territorial.

This study in the journal compared bonobo and chimpanzee brain microstructure, by looking at the ratio of tissue area occupied by structural elements like axons and synapses, against area occupied by cell bodies.

It was found that a higher proportion of axons, dendrites and synapses were found in specific regions of the bonobo brain when directly compared to those regions in the chimpanzee brain. This supports the hypothesis that comparatively increased presence of these connective elements may reflect variation in behavior between bonobos and chimpanzees.

When the research for this article was undertaken, Habon Issa was an undergraduate student at the George Washington University, something senior author Chet Sherwood noted as being particularly impressive upon her nomination for the award.

2020 runner-up Habon Issa

At the time of the articles publication, Habon had moved on to become a research technician in Mark Wus lab at John Hopkins University, studying genes influencing sleep timing and drive. Following on from this, she moved to New York University to begin a PhD with Robert Froemkes lab, identifying the neurons behind maternal motivation for interaction with young.

The key themes running through Habons experiences are her interest in the neuroanatomy, genes and molecular mechanisms relating to social and naturalistic behaviors.

Could you be a winner?

Were delighted that Hong-Hsi and Habon both published their research with Brain Structure and Function, and wish them both the best for their future research careers. The Editors Choice Award runs annually all submissions published in the previous year are eligible for nomination providing that they have a first author who is within the first ten years of their research career.

Want to be in with a chance to be considered for a future Editors Choice Award? Find out more about submitting to Brain Structure and Function.

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What makes a prize-winning paper? Observations from the 2020 Brain Structure and Function Editors' Choice Award - On Biology - BMC Blogs Network