Heres what happened under the Gold Dome on Thursday (December 5th):

Michael L. Testa, Jr. was sworn in as a member of the Senate for the 1st Legislative District.

SENATE ACTION (QUORUM)

Nominations Received and Referred to SJU:

TO BE A JUDGE OF THE SUPERIOR COURT:

Honorable James P. Wilson, J.S.C., of Plainfield.

Honorable Stephen J. Taylor, J.S.C., of Skillman.

Honorable Daniel R. Lindemann, J.S.C., of Wayne.

Honorable Jeffrey R. Jablonski, J.S.C., of Kearny.

Honorable Mitzy Galis-Menendez, J.S.C., of Cliffside Park.

Honorable Marlene Lynch Ford, J.S.C., of Seaside Park.

Honorable Angela White Dalton, J.S.C., of Howell.

Honorable Bradford M. Bury, J.S.C., of Watchung.

TO BE A MEMBER OF THE DELAWARE RIVER JOINT TOLL BRIDGE COMMISSION:

William E. Mandry, of Phillipsburg, to replace Garret Leonard VanVliet.

Nominations Withdrawn:

TO BE A MEMBER OF THE DELAWARE RIVER JOINT TOLL BRIDGE COMMISSION:

Philip J. Mugavero, of Phillipsburg, to replace Garret Leonard VanVliet.

Nomination Corrected Copy:

TO BE A MEMBER OF THE SITE REMEDIATION PROFESSIONAL LICENSING BOARD:

Michael J. Renzulli, of Upper Freehold Township *NOT* Robbinsville, to replace Constantine Tsentas.

Bills Introduced:

S4264 Pou,N William J Pascrell Jr. Highway-designates State Highway Route 19 REF STR

S4265 Bucco,A/OScanlon,D+1 Autistic person-voluntarily make notation on drivers lic, ID card & MV registry REF STR

S4266 Corrado,K Opioid antidote, administered-require involuntary commitment REF SHH

S4267 Cruz-Perez,N State contract award-bidder ineligible to receive if current contract in dispute REF SSG

S4268 Pou,N Cable television-incl cert fees/charges for svc in advertised price to consumers REF SCM

S4269 Weinberg,L Marriage license application-revises form, permit changes in middle and surname REF SJU

S4270 Gopal,V Energy efficiency standards-adopt for general service incandescent lamps REF SEN

S4271 Gopal,V Community College Opportunity Grant program-extend to volunteer emerg responders REF SHI

S4272 Cruz-Perez,N Municipal Rehabilitation and Economic Recovery Act-extend economic recovery term REF SCU

S4273 Gopal,V Disabled person-DEP required to develop beach accessibility guidelines REF SEN

S4274 Greenstein,L Integrated Case Management Services Program-DHS take certain measures concerning REF SHH

S4275 Smith,B Class I renewable energy-allows BPU to increase cost to customers 2022 thru 2024 REF SEN

S4276 Corrado,K Agriculture Development Committee-farmland preservation purposes;$31.153M REF SEN

S4277 Greenstein,L CBT revenues to St. Agric Devel Committee-mun planning incentive farmland grants REF SEN

S4278 Greenstein,L CBT revenues to St. Agric Devel Committee-co. planning incentive farmland grants REF SEN

S4279 Smith,B CBT rev. to State Agric Devel Committee-non-profit organizations farmland grants REF SEN

S4280 Ruiz,M Domestic violence orders-requires to be issued in other languages REF SJU

S4281 Smith,B Piscataway Regional Day School-requires State to sell land and improvements REF SSG

S4285 Sarlo,P SPRS member, 9/11 WTC-provides death benefits to surviving spouses & children REF SBA

S4287 Pou,N Insurance group-submit Corporate Governance Annual Disclosure to DOBI REF SCM

S4288 Singleton,T Homestead property tax reimbursement-proportionate owner collect entire amount REF SCU

S4289 Sweeney,S/Thompson,S Tax levy cap adjustment 2020-2021 thru 2024-2025-sch. districts losing State aid REF SBA

S4296 Pou,N/Sweeney,S+1 Health service corporation-reorganize into a mutual holding company system REF SCM

S4305 Sweeney,S Lobbyists-disclose professional services and filings w/State regulatory agencies REF SSG

Bills Recommitted:

S4204 ScaSca (2R) Sweeney,S Wages and hour and unemployment status-concerns employment status of individuals RCM SLA

Bills Reported from Committee/Given 2nd Reading:

A268 Kean,S/Egan,J+2 P.I.C.K. Awareness Act-authorize special license plate to support recovery REP

A442 AcaSca (2R) Schaer,G/Freiman,R+4 Revenue Advisory Board-establish, provide consensus revenue forecasting advice REP

A1582 AcaAcsScaSca (ACS/2R) Conaway,H/Moriarty,P+9 Dietetics and Nutrition Licensing Act-establish REP/SCA

A2431 Acs (ACS) Benson,D/Jimenez,A+13 Prescr. drug coverage-health insurers prov plans that limit patient cost-sharing REP

A3979 AcsSca (ACS/1R) Lopez,Y/Vainieri Huttle,V+10 Dignity for Incarcerated Primary Caretaker Parents Act REP/SCA

A4493 Aca (1R) Pinkin,N/Conaway,H Sexually transmitted disease-expedite partner therapy for treatment REP

A4608 Sca (1R) Zwicker,A/Downey,J+3 Behavior Analyst Lic Act-produce socially significant human behavior improvement REP/SCA

A5037 AcaAca (2R) Pintor Marin,E/Speight,S+4 Drugs, counterfeit-enhance penalties REP

A5802 Aca (1R) Greenwald,L/Downey,J+16 Family planning services-makes FY2020;$9.5M REP

S48 Sca (1R) Pou,N/Turner,S+1 Juvenile incarceration and parole-imposes restrictions REP/SCA

S469 Singer,R/Gopal,V+1 P.I.C.K. Awareness Act-authorize special license plate to support recovery REP

S618 Scs (SCS) Gordon,R/Oroho,S+2 State revenue estimating and reporting processes-reforms annual REP/SCS

S974 Singleton,T/Kean,T+3 Spinal muscular atrophy-requires newborn infants be screened REP

S993 Sca (1R) Vitale,J Sexually transmitted disease-expedite partner therapy for treatment REP

S1155 Ruiz,M/Rice,R+1 Property, vacant and abandoned-requires registration with municipalities REP

S1865 Scs (SCS) Weinberg,L/Kean,T+1 Prescr. drug coverage-health insurers prov plans that limit patient cost-sharing REP

S2448 Sca (1R) Diegnan,P/Singleton,T+2 Veterans and their spouses-waives certain prof. and occupational licensing fees REP

S2449 Sca (1R) Diegnan,P+2 Veterans and their spouses-waives commercial driver license fees REP

S2540 ScsSca (SCS/1R) Greenstein,L/Cruz-Perez,N+1 Dignity for Incarcerated Primary Caretaker Parents Act REP/SCA

S2625 ScsSca (SCS/1R) Weinberg,L/Ruiz,M Dietetics and Nutrition Licensing Act-establish REP/SCA

S2776 ScsScs (SCS) Smith,B/Greenstein,L+2 Plastic carryout bags, polystyrene & single-use straws-prohibits use REP/SCS

S2897 Madden,F/Singer,R+1 Mold hazard-DCA required to establish procedures for inspection and abatement REP

S2930 Bucco,A/Beach,J+1 Insurance producer licensing fee-exempts honorable discharged mil veterans REP

S3023 Sca (1R) Greenstein,L+2 Probation officers-union officials who represent participate in union activities REP/SCA

S3099 ScaScs (SCS) Weinberg,L/Kean,T+1 Behavior Analyst Lic Act-produce socially significant human behavior improvement

REP/SCS

S3170 ScaSca (2R) Cryan,J/Pou,N+3 Plant closings, mass layoffs-incr. prenotification time & requires severance pay REP/SCA

S3357 Sca (1R) Cunningham,S/Weinberg,L+3 Liberty St. Park Protection Act; estab. Advisory Committee & DEP related actions

REP/SCA

S3457 Sweeney,S/Andrzejczak,B+5 Hooked on Fishing-Not on Drugs Program;$450K REP

S3471 ScsSca (SCS/1R) Andrzejczak,B/Greenstein,L+2 Drugs, counterfeit-enhance penalties REP/SCA

S3759 Sca (1R) Addiego,D/Corrado,K+1 Special education unit-create within Office of Admin. Law; require annual report REP/SCA

S3870 Sarlo,P Sewerage systems, municipal-authorize alternative procedure for sale to pub util REP

S3920 Sca (1R) Pou,N Manufacturing fac-concern provisions of energy by prov cert energy related taxes REP/SCA

S3954 Oroho,S/Singleton,T+2 Labor Law Enforcement-establishes office REP

S4024 Pou,N William Paterson University;$2M REP

S4035 Pou,N/Singleton,T+1 Thomas Edison State University;$1.7M REP

S4083 Weinberg,L/Lagana,J.A. Bright side Manor, Teaneck-fund capital improvement costs;$1.5M REP

S4103 Sca (1R) Sweeney,S/Weinberg,L+1 Family planning services-makes FY2020;$9.5M REP/SCA

S4200 Ruiz,M/Turner,S Breakfast or lunch, reduced price-State pay difference REP

S4204 ScaSca (2R) Sweeney,S Wages and hour and unemployment status-concerns employment status of individuals REP/SCA

S4219 Sweeney,S Public works projects-revises definition to permit project labor agreements REP

S4225 Sca (1R) Greenstein,L/Madden,F Employer tax law-concerns joint liability for payment REP/SCA

Read the rest here:
Here's What Happened Under The Gold Dome On Thursday - InsiderNJ

In a way it seems so obvious: find out what kinds of things people are putting into their bodies by studying what comes out the other end. These do sound like muddy waters, but with some clever science researchers are able to draw some clear insights about the habits of different demographics of the population. And with their methods improving all the time, some see a bright future for this dark corner of science that involves real-time health monitoring, predicting disease outbreaks ahead of time and even tracking the rise of antibiotic resistance.

Just like a professional athletes urine sample can be checked for the presence of certain drugs, so too can ours. We dont all have an anti-doping official waiting at the bathroom door, but as our business makes its way into sewerage systems and pools with that of our neighbors, analysis of its chemical makeup can reveal the types of pharmaceuticals we have running through our bodies.

This field of science is known as wastewater-based epidemiology, and in the space of two decades has established itself as a valuable tool to track certain societal behaviors, but one with plenty more still to give.

In the early 2000s, scientists began to seriously explore the idea of tracking the use of illicit drugs by analyzing wastewater. This was inspired by the discovery of metabolites in lakes and rivers, which chemical analysis traced back to certain pharmaceutical compounds that had broken down in the waterways.

Some scientists saw no reason these same techniques couldnt be leveraged to track illicit drug use in the human population. The idea would be to sample wastewater at treatment plants and measure metabolites derived from illicit drugs, gathering non-incriminating drug usage data on the local population.

This is the first feasible approach to obtaining real-time data that truly reflects community-wide usage of drugs while concurrently assuring the inviolable confidentiality of every individual, wrote the EPAs Christian G. Daughton in the American Chemical Societys 2001 publication Pharmaceuticals and Care Products in the Environment. At the same time, this approach yields environmental data for a class of potential pollutants never before considered as such.

Daughton was onto something, it turns out. These days wastewater-based epidemiology has evolved to become a widely used tool by authorities all around the world. By sampling water from sewage treatment plants and measuring the chemical signals within it, scientists can make estimates on the quantity of drugs the community is using, and track the rise and fall of different drug types.

The SCORE network (Sewage analysis CORe group Europe) started out in 2010 as a collaboration between European scientists using wastewater analysis to track illicit drug use in different locations. At first, it involved 19 cities across the continent and by 2018 had expanded to cover 73 cities in 20 different European countries.

EMCDDA

This data is passed onto the European Monitoring Centre for Drugs and Drug Addiction, who work it into a publicly-available online tool that visualizes drug usage trends across the eight years of monitoring so far. By toggling different options, users can see hotspots for cocaine, amphetamine, methamphetamine and MDMA use across the continent, measured as milligrams consumed per 1,000 people each day.

And now other countries have gotten involved, helping to build a more complete picture of drug use around the world. An October paper published in the journal Addiction laid out the most recent data collected by the SCORE network, working with wastewater samples collected between 2011 and 2017, concerning more than 60 million people in 37 different countries.

It produced some interesting insights. For example, methamphetamine use was far more prevalent in North America and Australasia than in parts of Europe, though some hot spots emerged in Slovakia and the Czech Republic. Cocaine remains the drug of choice in Spanish, Italian, Swiss and French cities, while an overall upsurge was observed between 2011 and 2017. Ecstasy also grew in popularity in the cities sampled over the timeframe.

With this kind of generalized data on illicit drug consumption, the idea is that governments can better understand the role drugs play in the wellbeing of their communities. In turn, that can guide policy to curtail their harmful effects, whether that be through better use of police resources, more targeted awareness campaigns or the legalization of some substances that were seeing sweep through parts of the world.

Tying it all in with human behavior

The Australian government was an early adopter of wastewater-based epidemiology, starting out with a handful of testing sites in 2009 and now with a nationwide drug monitoring program in place. Through sewage samples, this initiative monitors the usage of 13 different substances, including nicotine, cannabis and opioid-based pain relievers, with local trends tracked through the help of chemistry researchers around the country. And some of them harbor grand ambitions for wastewater-based epidemiology.

Philip Choi is a PhD student using mass spectrometry and molecular biology to measure different aspects of population health through human waste. This extends beyond illicit drug use to include things like diet and the use of anti-depressants, making new connections between consumption habits and the lifestyles of the community.

The secret is to tie it all in with census data, which is exactly what Choi and his colleagues did the last time Australia conducted a nationwide census in 2016. The scientists had workers at treatment plants around the country freeze wastewater samples during the week of the census, and then mail them into Choi's lab at the University of Queensland for chemical analysis.

In searching these samples for certain biomarkers and comparing them to the census data, the team carried out the first ever study on the links between wastewater chemicals and social and economic measures of a population.

Prior to this study, some studies used wastewater-based epidemiology to study exposure to potentially harmful chemicals or pollutants such as pesticides, herbicides, flame retardants and so forth, Choi tells New Atlas. However, drug measurement studies made up the bulk of wastewater-based epidemiology studies. Additionally, previous studies measured what people are consuming. Our study is unique in that we show why people might consume different things.

And the results of the study, published in The Proceedings of the National Academy of Sciences in October, reveal some intriguing insights indeed. For example, the scientists found that the opioid-based pain reliever tramadol was used more heavily in areas where more people work as physical laborers. In areas populated by people with lower levels of education, they found higher use of anti-depressants and lower levels of dietary fiber. Some of these results were more surprising than others.

Before we analyzed our data, we expected socio-economically advantaged populations to have a better quality of diet, or take less drugs, and so forth, Choi explains. What was surprising, however, was that our data was able to show how specific aspects of socioeconomic advantage or disadvantage, such as having no home internet connection, lacking high school education, or having a high skilled occupation, were linked to diet or drug consumption. For example, we did not expect to find that lack of high school education was strongly linked to lower dietary fiber intake and higher consumption of amitriptyline, an antidepressant.

Higher caffeine and citrus consumption were other examples of habits tied to a strong socioeconomic status that revealed themselves through the wastewater samples. These new relationships that scientists are uncovering between human behavior and the chemicals in their sewage may prove highly valuable in building long-term pictures of population well-being, but could they also have an immediate impact, or even act as a warning sign of impending disaster?

As it stands, wastewater-based epidemiology is a laborious process that requires scientists to gather samples from different treatment plants and run chemical analyses to find out what's inside. But there could come a time when remote sensors built into treatment plants do most of the heavy lifting, and in much more expedient fashion.

"Some wastewater-treatment plants are already using inline sensors to measure specific chemicals in wastewater, such as online continuous monitoring of ammonium," Dr Jake O'Brien, a member of Choi's research team, explains. "There has been progress on developing more sophisticated biosensors for use in wastewater. Biosensors are small devices with a biological receptor, like DNA, an antibody, or a protein, that generates a signal in the presence of an analytical target, or analyte. They are already used for detection of disease biomarkers for both healthcare and environmental monitoring."

O'Brien points to sensor research being carried out at the UK's Cranfield University as an example of the exciting progress being made. Under the guidance of Dr Zhugen Yang, a research group at the university's Water Science Institute brings together cutting-edge biomedical and chemistry techniques to build next-generation sensors that connect wastewater with environmental science and human well-being. Yang also sees huge potential in using these techniques to offer a complete and immediate picture of population health.

"Wastewater-based epidemiology is very powerful to monitor the health at the community level," he tells us. "Compared to conventional analytical tools, sensors can provide rapid response times, ultra-sensitive detection of biomolecules, and the potential to be miniaturized for portable assays requiring minimal sample processing."

These tiny sensors Yang and his team are developing could be used to track pathogens in sewage that reveal outbreaks of certain diseases earlier on. Furthermore, he says they could also be tuned to track indicators of general health risks like diabetes, high blood pressure, sexually transmitted infections and even obesity.

"A recent report demonstrated that the level of an American citys obesity could be predicted by analyzing the bacterial community structure found in sewage," he explains.

Implementing these kinds of advanced sensors on a scale large enough to track population health sounds like a huge undertaking, and an expensive one. But Yang explains that the costs are something his team is already considering, and mightn't be as prohibitive as you'd think.

"Actually, generally those sensors are not so expensive, and we can really reduce the cost of sensors by using cheap material," he says. "For example, recently I have developed a paper-origami device, using filter paper as material to build up hydrophobic and hydrophilic channel to manipulate the liquid rather than using a pump. So I dont think the cost of sensors will be a main limitation for this kind of application."

The rise of antibiotic resistance bacteria, also known as superbugs, is a growing concern among scientists with many fearful they could return us to the dark ages of medicine and kill tens of millions a year by midway through the century. Wastewater-based epidemiology could emerge as a valuable tool in tracking their evolution, and the communities that are most at risk.

"Our recent work also demonstrated a low-cost later flow assay, which can be performed at the site of sample collection, with minimal user intervention, yielding results within 45 minutes and providing a method to monitor public health from wastewater," says Yang. "This can also be used for the tracking of antibiotic-resistant genes, with my research group currently working on the development for these kinds of sensors. The sensor will enable rapid monitoring of antibiotics and antibiotic resistant genes in wastewater."

There are still technical hurdles involved in building real-time sewage monitors to track human health, however. Yang says there are currently a handful of sensors that can perform real-time monitoring of chemical elements, but building versions to identify the right biological signals in real-time presents some unique challenges.

"As most current state-of-the-art sensor technologies for chemical and biological targets are mostly based on the bio-recognition element, the bio-receptor may become too saturated for a long-term detection during deployment, especially for the detection of the complex wastewater matrix," he says. "This is our opportunity to improve those sensors for wastewater-based epidemiology, which ultimately can be deployed for the real-time monitoring."

If these kinds of problems can be overcome, we could see humankind's excrement become an early warning system for some of its biggest health concerns. And then it might no longer be seen as waste at all.

Go here to read the rest:
The science of sewage: What your wastewater could reveal about you - New Atlas

Public relations professionals are in the business of not only getting exposure for their clients, but of making clients and journalists happy.

You can be the best public relations (PR) expert in the world, but if you lack people skills, youll never be truly successful. In PR, you have to understand human behavior and emotions, both in terms of your clients and the people you pitch to.

PR pros need to be jacks-of-all-trades. You have to be a master at writing, researching, communicating and organizing. But career success goes beyond the skills you learned in college. In fact, the key to good PR is something you learned in kindergarten: people skills.

Why Do PR Pros Need People Skills?

Degrees, certifications and a track record of successful campaigns will get you far in PR, but nothing works as well as people skills. People skills, like listening and compassion, are soft skills that are hard to measure, to be sure, but that doesnt mean they arent important.

In fact, in Ed Zitrons book This Is How You Pitch, he argues that PR success doesnt come from high-profile features. It comes from fostering long-term relationships with reporters. When youre good at making friends, you build a professional network of genuine, helpful relationships. Once its time to pitch your story, you have a swath of people to send that pitch to.

Think about it: If you got a pitch from a total stranger and a another from a good buddy who you grabbed a coffee with last week, which pitch would you choose? Chances are, youre going to go with the person you know.

If you arent getting responses to your pitches, theres a good chance its because you dont have an in with that journalist. But when you develop your people skills and grow professional relationships, you can score more media placements for your clients. On top of that, youll also be better at managing client relationships, ensuring repeat business and a loyal customer base. Its a win-win!

Three Methods To Improve Your People Skills

As humans, we learn people skills when were children. But just because were all grown up doesnt mean weve stopped learning. Follow these three tricks to improve your people skills and become a better PR professional.

1. Improve your emotional intelligence.

Believe it or not, humans make most decisions based on emotion, not logic. By improving your emotional intelligence, youll be able to connect to journalists, your clients and even the public on a more effective level.

Emotional intelligence is the awareness of emotions and how those emotions affect behavior. For example, with a healthy sense of emotional intelligence, you can sense when an editor is stressed out. You might wait to pitch them until you have their undivided attention.

In any situation, try to identify the other partys emotions. Ask why theyre feeling that way, how it affects their behavior and how your behavior will influence their emotions. At the end of the day, this comes down to having compassion for other people and using that sense of compassion to pitch smarter.

2. Listen!

You arent listening to me! has to be one of the most common sentences in the English language. Instead of being quick to speak, be quick to listen. Its not enough to hear what someone is telling you. Listening is an essential people skill thats about committing what someone says to memory, processing it and drawing conclusions. Its the single best way to show someone you care.

For example, if you dont follow a journalists instructions for a pitch, theyre going to be frustrated with you. Its going to look like you didnt listen. You may come off as tone deaf, and it will potentially ruin your chances of ever getting a media feature.

The next time youre chatting with someone, stop thinking about what youre going to say next. Theyre telling you what they need; all you have to do is listen.

3. Maintain relationships.

Relationships are like your bank account. You have to put money into that account regularly, and only occasionally make withdrawals. If you want to ask a journalist for a favor, you have to put more into the relationship than youre taking out of it. That means maintaining relationships and hanging out with a contact when you dont need anything.

This is easier said than done, especially if you know a lot of people in the media. To do regular outreach without losing your mind, set a calendar appointment twice a week to grab coffee with one of your contacts. Youll have a chance to catch up with people without asking for something in return. Chances are, once you send in a pitch, theyll be more than happy to help out because youve invested in the relationship.

The Bottom Line

If youre pitching stories to humans, you need to understand them. Thats why people skills are so important to the art of PR. By nurturing relationships within your network, youll have a trusted list of journalists you can pitch to score more stories. Your clients will benefit from your improved people skills, too.

See the original post:
Why People Skills Are Essential In PR And How To Improve Them - Forbes

After Year Of Record Grizzly Bear Deaths, Managers Talk Human-Bear Conflict Reduction

The last two years have been the deadliest on record for grizzlies in and around Glacier National Park. There have been at least 48 grizzly mortalities this year in the area, called the Northern Continental Divide Ecosystem (NCDE). As grizzly mortalities mount, bear managers in northwest Montana are trying to tackle the sources of rising deaths.

At a year-end meeting of bear managers on Tuesday, state bear biologist Cecily Costello said those numbers are nothing to worry about yet.

"Right now, Im not willing to say that two years of increased mortality is a trend. But I also am not gonna say that its not a trend. So Im just gonna have to say we wait and see what happens."

Costello says the population is still healthy and growing at over 1,000 bears. She says those 48 mortalities still fall below a state threshold for the ecosystem passed last year.

"At the same time that you can hear the number and be sad, you can also kind of celebrate in the fact that that many bears could die and we still have a viable population."

The grizzlies range is growing along with their population. Now, more private land is occupied by grizzly bears than public land. That leads to conflicts with property and livestock. So Costello says that high death rate, "may have a lot to do with the bear population, but it may have a lot do with us, as well."

Costello says human development and recreation have been on the rise. Citing a Headwaters Economics study from last year, she says between 1990 and 2016, nearly 300,000 acres of open space was converted to housing, and 30,000 new homes were built in the 9 counties that surround the Glacier region. She also says the number of cars entering the Park has nearly doubled since 2000.

Although Costello says heightened mortalities arent yet a risk to the grizzly population, bear managers are working to reduce the number of deaths. An interagency working group of federal, state, and tribal officials presented recommendations to address grizzly mortality at the meeting.

Hilary Cooley, grizzly bear recovery coordinator for the U.S. Fish and Wildlife Service, says she expects conflicts to continue to expand as human population and recreation continue to rise.

"These are tough issues, and its not gonna be enough to spend a few phone calls here working on these topics, and expect to have any change. We want to drop mortalities and drop conflicts," Cooley says.

Cooley identified hunters, roads, trains, chickens and trash as the primary drivers of conflict, based on trends over the last two decades. She presented recommendations to address each issue.

Trains killed eight grizzlies in Montana this year.

"This was a spike," Cooley says.

Train deaths have actually gone down since 1999, compared to the decade before it.

Cooley also says that cattle and sheep depredations, and conflicts over beehives have gone down over the same time period. However, other conflicts especially over chickens have skyrocketed.

Solutions ranged from education, outreach and collaboration, to intensive road projects that could help grizzlies safely pass through traffic, to formal regulations that could change human behavior. Across the board, funding was a key barrier to implementation. Cooley expects many of these recommendations to be implemented by 2021.

Grizzlies in the lower 48 were listed as threatened under the Endangered Species Act in 1975. In the Glacier area, state and federal biologists say the bears have recovered. At the meeting, State Sen. Bruce Gillespie says those bears have been federally protected long enough.

"Lets promote a model that gets the grizzly bear delisted, hopefully by next year, and on to a management plan."

In public comment, citizens addressed human safety issues, took issue with U.S. Forest Service projects that compromised bear habitat, and said grizzlies have a long way to go to reach meaningful recovery.

Josh Osher is the Montana Director for the conservation group, the Western Watersheds Project.

"Within a tiny little period of history they were shrunk to almost nothing," Osher said. "So I dont see 44 years as all that long to think about in term of the time it takes to recover a species."

The Interagency Grizzly Bear Executive Committee will hold its year-end meeting, which will address mortality and other issues across all grizzly ecosystems, on December 16 at the Residence Inn in Missoula.

See the original post here:
After Year Of Record Grizzly Bear Deaths, Managers Talk Human-Bear Conflict Reduction - MTPR

In Rowan Universitys Center for Behavior Analysis, professors who are Board Certified Behavior Analysts (BCBA-D) and their students take on difficult problems of human concern across diverse populations, needs, and settings.

Each week, they spend hours striving to teach a nonverbal child as young as two to communicate. In specially equipped rooms, therapists don protective equipment to work with children whose severe behavior extends to harming themselves or others. They find ways to help users finally quit smoking for good.

In the center, the lines between education, research and service often blur, in all the best ways. Rowan students provide services to community members as part of the training and research that will inform the future of behavior analysis.

Understanding behavior analysis

"Most people dont really know what behavior analysis is, said Dr. Mary Lou Kerwin, professor of psychology and executive director of the Center for Behavior Analysis, located in Robinson Hall. Behavior analysis is the use of scientific principles to explain and change behavior.

Unfortunately, the use of behavioral principles is so ubiquitous that people often assume they understand how to use these strategies effectively. But behavior analysis is actually complex.

If you understand how an individual behaves, you can predict future behavior, Kerwin explained. That provides potential for social change in society in general, and we can improve quality of life at the individual levels.

Humans are complicated, said Dr. Bethany Raiff, associate professor and director of the Health and Behavioral Integrated Treatments (HABIT) Research Unit, and one of the most complicated things is trying to figure out why people do what they do.

Building a better quality of life for children with autism

Much of the work done in the Center for Behavior Analysis involves treating children with autism spectrum disorder (ASD).

The centerprovidesaffordable treatment and education to the parents of children with autism, said Jacqueline Logan, BCBA and research coordinator at the center. Besides benefitting from the variety of different assessments and individualized treatments offered through the center, the children and their families are participating in research that will help advance the field as a whole.

What we know from over 25 years of research is that the earlier the intervention is provided, the better the outcome for the child, Kerwin explained. That intervention is often intensive, taking so many hours each week that it's not always feasible to use more than one type of intervention. Thats why its crucial that the intervention used is the most effective option possible.

A lot of interventions have no empirical support but sound good to parents who are desperate to help their child, Kerwin said. Interventions based on behavior analysis, however, do have empirical support. One remaining question with these interventions is which behavior analytic interventions work best for whom and when.

Children with autism spectrum disorder all have different needs and different deficits. Although the myth that autism manifests in the same way in every child was debunked years ago, treatment has continued to be one-size-fits-all, Kerwin explained.

If we're engaging in hours and hours of something that's not effective, were missing the opportunity to do something that is effective, potentially limiting a child's ability to improve over time, Kerwin said.

Autism intervention approaches go head-to-head in grant-funded SMART study

Evaluating the efficacy of different interventions is the focus of the SMART (Sequencing for Maximizing Acquisition and Response to Treatment) study Dr. Michelle Soreth, associate professor of psychology, is leading with co-investigator Kerwin. The goal is to maximize that ability to improve communication skills over time for children participating in the study as well as ultimately for other children with ASD.

Soreth and Kerwin initially tested applied behavior analysis (ABA) interventions against a non-ABA form of intervention called Relationship Development Intervention (RDI). This research was conducted under the first of two grants awarded by the New Jersey Governors Council for Medical Research and Treatment of Autism and the New Jersey Department of Health. The outcomes of their interventions showed that parent-implemented ABA was a particularly powerful tool in the treatment of autism.

What this first study did not do was establish which types of treatments within the field of ABA were the most effective. Thats the goal of Soreth and Kerwins current research, funded by a second grant from the Department of Health, which pits the original model of ABA-based early intervention for autism, Discrete Trial Instruction (DTI), against a newer ABA-based intervention model known as the Verbal Behavior Approach (VBA).

Although researchers are just finishing data analysis, preliminary findings indicate that children in the VBA group learned new skills at twice the rate of children in the DTI intervention group.

Given that one of the best indicators of overall prognosis for children diagnosed with autism is whether the child is speaking in phrases before age five, its almost as though we are working against the clock, explained Soreth, who focuses primarily on the significance of intervention with children as young as two years of age.

If we are able to identify interventions that double the rate of progress during such a critical learning period, imagine the possibilities for improving the overall prognosis and quality of life for individuals diagnosed with autism, Soreth added.

Addressing severe behavior SAFE-ly

Dr. Christina Simmons, assistant professor of psychology, specializes in treating populations others might shy away from because of their severity. In her Social Acceptability and Functional Evaluation of Behavior (SAFE Behavior) Lab and Severe Behavior Clinic, she works with school-aged children from three to 18 who exhibit severe behavior, such as aggression, property destruction, and self-injurious behavior. Many of these children present with autism and other developmental disabilities.

Simmons embraced this work early on in her academic career. As an undergraduate working with a nonverbal 13-year old with autism, Simmons gained insight into why the child would destroy property and, at times, resort to self-injurious behaviors.

She was trying to communicate with her destructive behaviors, Simmons said. Thats when I discovered ABA as an evidence-based approach for treating severe behavior.

The goals she and the students working under her supervision have are pretty clear-cut: reducing challenging behaviors and developing appropriate functional skills. How to accomplish those objectives is trickier.

"How do we promote meaningful change, not just in clinical environments but also in the childs natural environment? asked Simmons.

Theres no one answer that works for all children and all scenarios. But, for now, Simmons and her students are working to improve the assessment and treatment process to promote socially meaningful outcomes. All of my research is applied, said Simmons. In addition to my research lab, I work closely with graduate students in practicum and undergraduate students gaining fieldwork hours.

The students are eager to learn, especially in a unique environment like the Severe Behavior Clinic, and families get high-quality and enthusiastic helpa genuine win-win.

Behavioral economics and healthy choices

With her HABIT lab, Raiff demonstrates that behavior analysis has applications for adults as well as children. She specializes in a field known as behavioral economics.

I try to understand how people make choices and how to shift decisions towards healthier choices, she explained. Better health choices often result in delayed rewards, whereas unhealthy choices often result in immediate rewards.

When those unhealthy behaviors win out, its because the immediate benefit is more powerful than the potential benefit of better health later. Whether youre picking junk food over a healthy salad for reasons like taste or time, or binge watching a show over going to the gym, youre making a choice.

In the field of behavioral economics, its often easy to figure out what drives people to choose the unhealthy behavior. The more difficult task is discovering effective ways to alter that behavior.

Incentives that are arranged and delivered immediately much like those immediate rewards of making unhealthy choices can shift choices toward healthy behavior, Raiff said.

The use of financial incentives, sometimes called contingency management, has proven effective in helping people quit smoking and give up drugs. Of course, theres a problem with this traditional type of reward: it costs money.

Raiff is researching other, more sustainable methods of applying these immediate reward systems. Competition tends to be a big motivator. She recently received a grant from the National Institutes of Health to research the efficacy of another form of incentive: video game rewards.

We want to see if the virtual rewards earned in a mobile game help induce abstinence from smoking, she said. Were paving the way to make a more affordable option. The video game has great potential and is really different from anything else out there for smoking cessation.

Raiffs work is ongoing, but she and her team are making great strides.

Were not there yet in terms of execution but, through testing, were learning a lot about what kinds of games are effective and how to keep users engaged, she said. We definitely have found an interest among users.

Raiff also is collaborating with physicians at Cooper University Hospital on two Camden Health Research Initiative grants awarded by Rowan University. Shes beginning to test contingency management interventions to increase treatment adherence among individuals diagnosed with opioid use disorder and to initiate smoking abstinence among individuals diagnosed with schizophrenia spectrum disorder.

Where research meets service

Research and service to the community are two of the three principles on which the Center for Behavior Analysis was founded. Theres a critical need, said Simmons of the service component. Especially in our area, there are not sufficient intensive services for children with severe behavior concerns.

Service to the community can take many forms. Although families can come in to receive treatment through outpatient clinics in Robinson Hall, the University also coordinates with the county care management organizations in the statewide Childrens System of Care (CSOC). Answering the states Request for Qualified Providers (RFQ) for more than two years, faculty, undergraduate and graduate students and alumni involved in the Center for Behavior Analysis offer intensive in-home behavioral services (IIH) and Individual Support Services (ISS) for children with intellectual disabilities in their own homes.

These services give both our undergraduate and graduate students a unique opportunity to work directly with children with developmental disabilities who have complex behavioral needs under the supervision of our faculty and alumni, said Simmons, who, along with her students, is highly involved in these in-home services. Through these experiences, they gain valuable clinical skills and confidence to work with this specialized population after graduation from our programs.

An extraordinary opportunity for students of behavior analysis

What of that third principle of the center? Education doesnt take a backseat to research and service. Instead, its a unique curriculum, along with these research and service opportunities, that makes Rowans undergraduate and graduate programs in Behavior Analysis stand out.

Rowan is a hotbed of behavior analytic activity, said Kerwin. In our discipline, everyone knows where Rowan is. Undergraduate coursework available through the Department of Psychology prepares students to become Board Certified assistant Behavior Analysts (BCaBA), and the schools graduate programs can lead to the Board Certified Behavior Analyst (BCBA) credential.

The Center for Behavior Analysisprovided mehands-on training and knowledge, not only throughresearch practices but throughapplied techniques used in the field of Applied Behavior Analysis, said Logan, who completed her Master of Arts in Behavior Analysis degree in 2018. I was ableto work closelywith myprofessors toreceive feedback and training that gave me the skills to become a Board CertifiedBehavior Analyst.

Studies in applied behavior analysis can equip students with the skills to work with these same patient populations after graduation. This coursework can also prepare them to translate the skills of behavior analysis to work with a broad range of individuals in a variety of settings.

The principles can be applied in so many ways, from medical uses such as teaching child patients to stay still in an MRI machine and swallow pills to applications in organizational behavior management, said Kerwin. We anticipate that the scope of research in the Center for Behavior Analysis will continue to expand as the true potential of behavior analysis as a broad health profession begins to be fully recognized.

Read this article:
Treating autism, severe behavior and addiction - Rowan Today

Share this Article

You are free to share this article under the Attribution 4.0 International license.

Using a mathematical framework with roots in artificial intelligence and robotics, researchers have uncovered the process for how people make decisions in groups.

The researchers also found they could predict a persons choice more often than more traditional descriptive methods.

In large groups of essentially anonymous members, people make choices based on a model of the mind of the group and an evolving simulation of how a choice will affect that theorized mind, the study finds.

Our results are particularly interesting in light of the increasing role of social media in dictating how humans behave as members of particular groups, says senior author Rajesh Rao, a professor in the University of Washingtons Paul G. Allen School of Computer Science & Engineering and co-director of the Center for Neurotechnology.

We can almost get a glimpse into a human mind and analyze its underlying computational mechanism for making collective decisions.

In online forums and social media groups, the combined actions of anonymous group members can influence your next action, and conversely, your own action can change the future behavior of the entire group, Rao says.

The researchers wanted to find out what mechanisms are at play in settings like these.

In the paper, they explain that human behavior relies on predictions of future states of the environmenta best guess at what might happenand the degree of uncertainty about that environment increases drastically in social settings. To predict what might happen when another human is involved, a person makes a model of the others mind, called a theory of mind, and then uses that model to simulate how ones own actions will affect that other mind.

While this act functions well for one-on-one interactions, the ability to model individual minds in a large group is much harder. The new research suggests that humans create an average model of a mind representative of the group even when the identities of the others are not known.

To investigate the complexities that arise in group decision-making, the researchers focused on the volunteers dilemma task, wherein a few individuals endure some costs to benefit the whole group. Examples of the task include guarding duty, blood donation, and stepping forward to stop an act of violence in a public place, they explain in the paper.

To mimic this situation and study both behavioral and brain responses, the researchers put subjects in an MRI, one by one, and had them play a game. In the game, called a public goods game, the subjects contribution to a communal pot of money influences others and determines what everyone in the group gets back. A subject can decide to contribute a dollar or decide to free-ridethat is, not contribute to get the reward in the hopes that others will contribute to the pot.

If the total contributions exceed a predetermined amount, everyone gets two dollars back. The subjects played dozens of rounds with others they never met. Unbeknownst to the subject, a computer mimicking previous human players actually simulated the others.

We can almost get a glimpse into a human mind and analyze its underlying computational mechanism for making collective decisions, says lead author Koosha Khalvati, a doctoral student in the Allen School. When interacting with a large number of people, we found that humans try to predict future group interactions based on a model of an average group members intention. Importantly, they also know that their own actions can influence the group. For example, they are aware that even though they are anonymous to others, their selfish behavior would decrease collaboration in the group in future interactions and possibly bring undesired outcomes.

In their study, the researchers were able to assign mathematical variables to these actions and create their own computer models for predicting what decisions the person might make during play. They found that their model predicts human behavior significantly better than reinforcement learning modelsthat is, when a player learns to contribute based on how the previous round did or didnt pay out regardless of other playersand more traditional descriptive approaches.

Given that the model provides a quantitative explanation for human behavior, Rao wonders if it may be useful when building machines that interact with humans.

In scenarios where a machine or software is interacting with large groups of people, our results may hold some lessons for AI, he says. A machine that simulates the mind of a group and simulates how its actions affect the group may lead to a more human-friendly AI whose behavior is better aligned with the values of humans.

The results appear in Science Advances.

Additional coauthors are from UC Davis; New York University; and the Institut des Sciences Cognitives Marc Jeannerod. The National Institute of Mental Health, the National Science Foundation, and the Templeton World Charity Foundation funded the work.

Source: Jake Ellison for University of Washington

See the original post:
Trying to read the 'mind of a group' shapes our decisions online - Futurity: Research News

The study, published inScience Advances, results from the collaboration between a UB team led by Cedric Boeckx, ICREA professor from the Section of General Linguistics at the Department of Catalan Philology and General Linguistics, and member of the Institute of Complex Systems of the UB (UBICS), and researchers from the team led by Giuseppe Testa, lecturer at the University of Milan and the European Institute of Oncology.

An evolutionary process similar to animal domestication

The idea of human self-domestication dates back to the 19th century. It is the claim that anatomical and cognitive-behavioral hallmarks of modern humans, such as docility or a gracile physiognomy, could result from an evolutionary process bearing significant similarities to the domestication of animals.

The key role of neural crest cells

Earlier research by the team of Cedric Boeckx had found genetic similarities between humans and domesticated animals in genes. The aim of the present study was to take a step further and deliver empirical evidence focusing on neural crest cells. This is a population of migratory and pluripotent cells - able to form all the cell types in a body - that form during the development of vertebrates with great importance in development. "A mild deficit of neural crest cells has already been hypothesized to be the factor underlying animal domestication. Could it be that humans got a more prosocial cognition and a retracted face relative to other extinct humans in the course of our evolution as a result of changes affecting neural crest cells?" asks Alejandro Andirk, PhD students at the Department of Catalan Philology and General Linguistics of the UB, who took part in the study.

To test this relationship, researchers focused on Williams Syndrome disorder, a specific human neurodevelopmental disorder characterized by both craniofacial and cognitive-behavioral traits relevant to domestication. The syndrome is a neurocristopathy: a deficit of a specific cell type during embryogenesis. In this case, neural crest cells.

In this study, researchers from the team led by Giuseppe Testa used in vitro models of Williams syndrome with stem cells derived from the skin. Results showed that the BAZ1B gene -which lies in the region of the genome causing Williams Syndrome- controls neural crest cell behavior: lower levels of BAZ1B resulted in reduced neural-crest migration, and higher levels produced greater neural-crest migration.

Comparing modern human and Neanderthal genomesResearchers examined this gene in archaic and modern human genomes. "We wanted to understand if neural crest cell genetic networks were affected in human evolution compared to the Neanderthal genomes", Cedric Boeckx said.

Results showed that that BAZ1B affects a significant number of genes accumulating mutations in high frequency in all living human populations that are not found in archaic genomes currently available. "We take this to mean that BAZ1B genetic network is an important reason our face is so different when compared with our extinct relatives, the Neanderthals," Boeckx said. "In the big picture, it provides for the first time experimental validation of the neural crest-based self-domestication hypothesis," continues.An empirical way to test evolutionary claims

These results open the road to studies tackling the role of neural crest cells in prosociality and other cognitive domains but is also one of the first examples of a potential subfield to test evolutionary claims. "This research constitutes one of the first studies that uses cutting-edge empirical technologies in a clinical setting to understand how humans have evolved since the split with Neanderthals, and establishes Williams Syndrome in particular as a unique atypical neurodevelopmental window onto the evolution of our species," Boeckx concludes.

Reference: Zanella et al. 2019.Dosage analysis of the 7q11.23 Williams region identifies BAZ1B as a major human gene patterning the modern human face and underlying self-domestication. Science Advances.DOI: 10.1126/sciadv.aaw7908.

This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source.

View post:
A Genetic Network Sheds Light on the Evolution of the Modern Human Face - Technology Networks

Now this is joyous news! Ho ho ho!

Two of the biggest US earthquake faults might be linked:Provocative analysis of sea-floor cores suggests that quakes on the Cascadia fault off California can trigger tremors on the San Andreas.

But its not as if geological or seismic factors can affect human life in any significant way!

How a volcanic eruption helped create modern Scotland

***

Some quotations fromTim Keller,Making Sense of God: An Invitation to the Skeptical:

The declaration that science is the only arbiter of truth is not itself a scientific finding. It is a belief. (35)

Russian philosopher Vladimir Solovyov sarcastically summarized the ethical reasoning of secular humanism like this: Man descended from apes, therefore we must love one another. The second clause does not follow from the first. If it was natural for the strong to eat the weak in the past, why arent people allowed to do it now? . . . Given the secular view of the universe, the conclusion of love or social justice is no more logical than the conclusion to hate or destroy. These two sets of beliefsin a thoroughgoing scientific materialism and in a liberal humanismsimply do not fit with one another. Each set of beliefs is evidence against the other. Many would call this a deeply incoherent view of the world. (4243)

The humanistic moral values of secularism are not the deliverances of scientific reasoning, but have come down to us from older times . . . they have a theological history. And modern people hold them by faith alone. (43).

If you say you dont believe in God but you do believe in the rights of every person and the requirement to care for all the weak and the poor, then you are still holding on to Christian beliefs, whether you will admit it or not. Why, for example, should you look at loveandaggressionboth parts of life, both rooted in our human natureand choose one as good and reject one as bad? They are both part of life. Where do you get a standard to do that? If there is no God or supernatural realm, it doesnt exist. (4748)

While there can be moralfeelingswithout God, it doesnt appear that there can be moralobligation. (178)

A moral judgment about something can never be made apart from an examination of its given purpose. . . . How, then, can we tell if a human being is good or bad? Only if we know our purpose, what human life isfor. If you dont know the answer to that, then you can never determine good and bad human behavior. (18687)

If your premise that there is no God leads most naturally to conclusions you know are not truethat moral obligation, beauty and meaning, the significance of love, our consciousness of being a self are illusionsthen why not change the premise? (227)

See the rest here:
Is science the only arbiter of truth? - Patheos

Josef Stalin is reputed to have said: The death of one man is a tragedy. The death of millions is a statistic. In the hands of New York Times columnist Paul Krugman, the deaths of thousands can be a partisan bludgeon.

A number of scholars have pondered the recent rise in deaths of despair those attributed to alcoholism, suicide and drug overdoses. Krugman sees a chance to make a crude red state/blue state comparison.

I looked at states that voted for Donald Trump versus states that voted for Clinton in 2016, and calculated average life expectancy weighted by their 2016 population. In 1990, todays red and blue states had almost the same life expectancy. Since then, however, life expectancy in Clinton states has risen more or less in line with other advanced countries, compared with almost no gain in Trump country. At this point, blue-state residents can expect to live more than four years longer than their red-state counterparts.

So, vote Democrat, live four years longer?

Krugman muses that many blue states expanded Medicaid and that obesity tends to be higher in red states. Residents of blue states also have higher levels of education. Thats about the sum of his analysis, but its enough for him to declare that the conservative diagnosis of what has gone wrong in America, i.e. that the decline of traditional values has had negative effects, is dead wrong.

Sentence first, verdict afterward said the Red Queen. Comparing red states and blue states this way is facile.

First, its essential to stress that the decline in life expectancy is a nationwide phenomenon that hits all ethnic groups and both sexes. Of the states with the worst statistics West Virginia, Ohio, New Hampshire, Maine, and Vermont three are blue states, one is red, and one is purple.

It seems dubious to assume that Medicaid expansion, which happened mostly within the past five years, could have had such a dramatic effect in so short a time. Some of the states that expanded Medicaid, like Louisiana and Alaska, have some of the highest rates of premature deaths. Only 14 states have not expanded Medicaid, and they are disproportionately poorer states in the Deep South.

We do know that these deaths of despair as Princetons Anne Case and Angus Deaton dubbed them, are the result of behaviors. Unlike in poorer countries, where impure drinking water or infectious disease takes a large toll, our premature deaths arise from drug addiction, alcohol abuse, and suicide.

Suicide is on the rise, not just among middle-aged and older Americans, but among the young as well. Between 2007 and 2017, youth suicide increased by 56%, and suicide attempts quadrupled. The prime suspect here is social media. Instagram, Snapchat, Twitter and their competitors can induce anxiety and depression among teenagers eager for peer approval. Many spend most of their waking hours unnaturally attached to screens, which deliver pleasure but also bullying and belittling. A high-school teacher noted that the cafeteria used to be the noisiest room in the school. No longer. Its now a tableau of darting fingers and uneasy eyes.

Maybe social media is not the problem. Its probably too soon to know. Human behavior is complicated. Some states have more guns than others (which contributes to suicide deaths). Some have more access to Fentanyl.

There is no debate in the literature that the decline of two-parent families is associated with poorer outcomes for children (though divorce sometimes makes adults happier). And there is emerging evidence that loneliness another effect of family breakdown has become more of a public health problem than obesity. Men raised in fatherless homes are more prone to joblessness, drug addiction and a range of other troubles than those raised by two parents. They are also more vulnerable and damaged than their sisters who are raised in the same circumstances.

Heres the twist, and the part Krugman completely missed: Many of the people in blue states who are keeping the life expectancy figures up are actually living in a traditional way, even if they vote Democrat. The college-educated upper-third in America follows bourgeois virtues. They get an education, get a job, get married and have children, in that order. The blue states are full of them. New Mexico and Alabama, not so much.

So its Krugmans partisan point scoring, not the conservative diagnosis, thats dead wrong.

Mona Charen is a senior fellow at the Ethics and Public Policy Center. Her column is distributed nationally by the Creators Syndicate.

More:
Charen: Red death, blue health? - The Winchester Star

Whether its your grandpas nose, your mothers eyes, or the chin the entire family share, humans depend on facial features to tell one another apart, to read emotions and intent, and to communicate with others. But why we share these features, and not others, has long remained a mystery.

Now, a new study published this week in Science Advances suggests the reason our human faces look like they do is due to a long history of accumulated genetic mutations.

Its likely this is no biological accident. The finding supports the theory of self-domestication, which is the idea that ancient people chose to mate with more docile partners and used facial appearance as clues as to who was the least aggressive.

The study argues that mutations associated with gene BAZ1B which is present in all animals drove the human face to have slimmer features than our ancient hominid peers, Neanderthals and Denisovans. It may also have played a role in the development of cooperative societies, the study suggests.

Ancient humans who carried a mutated BAZ1B gene were selected as mates more often, the study suggests passing these mutations through the population.

BAZ1B mutations affect human behavior as well as the development of craniofacial features the gene is linked to Williams syndrome, a genetic condition characterized by an highly social disposition.

The modern human face acquired its shape as an instance of mild neurocristopathy when something is off with the development of an embryos neural crest the study suggests.

The neural crest gives rise to some of the bodys most crucial cells, including those that eventually make up the craniofacial bones. The neural crest has also been linked to animal domestication, the authors tell Inverse. That led them to examine how BAZ1B in the human neural crest affects our body.

Previous work involving individuals with Williams syndrome shows that they tend to have softer facial features compared to the general population, as well as friendly dispositions. Stem cells harvested from these individuals revealed they either had duplicated or deleted BAZ1B genes, indicating that it plays a crucial role in facial features.

The researchers then examined the genotypes of one Denisovan and two Neanderthals to see how BAZ1B was expressed as compared to modern humans who do not have Williams syndrome. In the modern human sample, a subgroup of the genes regulated by BAZ1B 40 percent of the genes expressed by human neural-crest stem cells had fixed mutations in their regulatory regions, according to the study.

This suggests that BAZ1B genes play a powerful role in the evolution of the modern human face and the tendency for sociability generally found across our societies. While it may not seem it all the time, scientists generally consider us a domesticated species we co-operate and interact socially.

The findings jibe with past research suggesting Neanderthals and Denisovans dont have genes linked to domestication in humans indicating that something happened in the course of human evolution to make us more social.

While the study does add to the evidence for the self-domestication theory, it is important to consider it context of the theorys origins. The theorys first proponent, Johann Blumenbach, infamously invented the word Caucasian and placed them at the top of a hierarchical pyramid of races. These findings do not mean that facial traits can be used to define an individuals aggressiveness or any other characteristics, the authors say. Thats just the racist and sexist pseudoscience of physiognomy.

The self-domestication theory that we support claims that there might have been a process of self-selection that was based on the selection of less aggressive individuals, indirectly selecting those who had a reduced neural crest production, the team explained to Inverse in an emailed statement. The self-domestication assumptions do not refer to single individuals, but to the entire humankind.

Conditions like Williams syndrome are rare examples in which facial traits can help diagnose the condition. But personality is much more the byproduct of our interactions and environment.

In our evolutionary past, its possible that our ancestors unknowingly selected mates based on certain traits, and that led us to look distinctly human. But facial features can come in all shapes and sizes studies suggest that the wide variety of features we see today are a result of evolutionary pressure to make individuals recognizable as, well, individuals.

Abstract:

We undertook a functional dissection of chromatin remodeler BAZ1B in neural crest (NC) stem cells (NCSCs) from a uniquely informative cohort of typical and atypical patients harboring 7q11.23 copy number variants. Our results reveal a key contribution of BAZ1B to NCSC in vitro induction and migration, coupled with a crucial involvement in NC-specific transcriptional circuits and distal regulation. By intersecting our experimental data with new paleogenetic analyses comparing modern and archaic humans, we found a modern-specific enrichment for regulatory changes both in BAZ1B and its experimentally defined downstream targets, thereby providing the first empirical validation of the human self-domestication hypothesis and positioning BAZ1B as a master regulator of the modern human face. In so doing, we provide experimental evidence that the craniofacial and cognitive/ behavioral phenotypes caused by alterations of the Williams-Beuren syndrome critical region can serve as a powerful entry point into the evolution of the modern human face and prosociality.

See the article here:
"Self-domestication" may have led to the modern human face - Inverse