Category Archives: Human Behavior

5 Reasons Why Bitcoin Price Crashed Amid The Coronavirus Financial Crisis – CryptoPotato

Along with every other financial instrument led by the global stock markets, Bitcoin plummeted in the past two weeks following the worldwide spread of the coronavirus.

Following their desire to see Bitcoin emerging as the next generations safe-haven asset, this latest severe Bitcoin plunge felt like a nightmare for many Bitcoiners.

The following article will try to examine what led to the massive sell-off and will end in a little hope that Bitcoin might not have said its final word yet regarding its role in the monetary world.

Wall Street recorded some of its worst trading weeks; the main indexes are already 20-25% away from their all-time highs reached just a month ago. The hit was so intense that the New York Stock Exchange had to halt trading on a few occasions to minimize the damages, for the first time since 2008.

The drop didnt skip the cryptocurrency market. Still generally accepted as a riskier investment, Bitcoin, and most coins, dropped by as much as 50% in a matter of days.

The most brought up reason for those sell-offs is the basic human need for stable liquid assets also known as cash. When the financial situation is at risk, people revert to a more state-of-survival mode. As such, they need to cover their essential needs, such as housing, food, and, yes, toilet paper. Investing is no longer a priority.

As of writing these lines, you cant buy toilet paper or food with Bitcoin. Only with cash.

Among the sellers, there were large portions of institutional money. As the crypto community was blessing the institutional money and hedge funds that came to buy Bitcoin lately, we have to remember that they are buying Bitcoin for investment purposes only. These were also rushing to cash out their crypto portfolio along with their global markets equities.

The cryptocurrency market is very young in the financial world. Additionally, its still relatively small, and there is no central authority behind it since Bitcoin is decentralized.

Thus, violent moves and fluctuations are a natural way of life for BTC, which also raises concerns among some investors about the value of their assets. This could also lead to mass sales in times of panic.

Besides, the list of Bitcoin leveraged trading exchanges, such as BitMEX and Binance Futures, has been continuously growing in numbers to cope with the increasing demand for speculative traders who want to utilize margin trading. As such, Bitcoin has become more of a speculative asset, instead of an actual store of value.

The effects are evident and received proof last week. While the price of BTC was tumbling, the Futures trading volume skyrocketed, ultimately leading to record-breaking liquidations. Such developments could quickly accelerate the price drop.

Interestingly, at the precise time of Bitcoins most severe drop to $3,600, BitMEX went offline due to technical issues. Yet, members of the community, including another popular exchange FTX asserted doubts if there were any technical problems at all.

This reason is actually not related to the coronavirus crisis; however, since the Bitcoin price was declining lately, it might have seen a boost in its selling process.

The PlusToken was a Ponzi scheme, which was abandoned in 2019. It was another classic pyramid scheme, just like Bitconnect.

The Ponzi promised its investors double-digits monthly returns; hence it was a matter of time until the fraudulent project, originated in China and Korea, had disappeared with the money.

The wallets of the company had cryptocurrencies worth over $3 billion on the date the project was abandoned. Later that year, and only recently, blockchain transactions proved that the founders are mixing their coins in order to sell them and cash out.

The most recent PlusToken transaction was on March 8, 2020, when 13,000 Bitcoins worth $105 million at that time were mixed in their way to be dumped on the market.

Its still unknown whether the PlusToken founders had sold all their coins, however, eventually, it will end someday.

According to an ongoing investigation of blockchain transactions, many of the recent Bitcoin sales came from investors who have acquired the coins in the past 1-2 years. They are cashing out mostly in a loss. Human behavior is fed from the fear of losing some.

The HODLers have been around for many years and have experienced other significant price drops, such as the 2018 crypto bubble burst that brought the price of Bitcoin from a high of $20,000 to $3,200 in less than a year. The early adopters are aware that, generally, when Bitcoin goes down, it recovers over time.

The precious metal is often regarded as the ultimate safe-haven asset. Consequently, it should have been performing rather well during the latest financial crisis, the Sub-Prime, one could assume.

The situation, though, is slightly more complicated. During the last global financial crisis in 2008, and more specifically in March that year, when the Federal Reserve had to rescue the corporate bank Bear Stearns, Gold exploded to over $1,000 per troy ounce. Later on, however, when the recession worsened, instead of continuing its decisive run, the precious metal tumbled.

Then, on Monday, September 15th, 2008, the crisis reached its climax when the U.S. bank Lehman Brothers filed for bankruptcy. In those six months, Gold plummeted to $775 and even lower in the following weeks. Only after the recession ended and investors returned to the markets, Golds price skyrocketed before it eventually exceeded $1,200 in January 2010.

None of the above, though, shook Golds perception as a safe haven. It only means that when push comes to shove, most investors panic sell their assets leading to price descends, and this includes Bitcoin and the other cryptocurrencies.

Born dues to the 2008 recession, Bitcoin is yet to reach its real purpose. Its supposed to be an electronic peer-to-peer cash system, but so far, it has been used mostly for a speculative form of investment.

All of this could change as quickly in case the peoples trust in the current banking system deteriorates. Banks were behind the 2008 recession mentioned above. Governments were forced to bail a lot of them out, but the mass opinion has already been shaken.

Today, the outbreak of the coronavirus seems like only the pin to pop the inflated bubble, which will expose many dirty secrets.

In a situation where banks will continue printing money, which will deflate its value, people might eventually start looking for alternative means of payments outside of governments and banks. That could be the glory moment Bitcoin had been waiting for.

However, this situation is far from reality, as of now, and no one guarantees the price of Bitcoin wont continue to tumble even more.

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5 Reasons Why Bitcoin Price Crashed Amid The Coronavirus Financial Crisis - CryptoPotato

[OPINION] I’m a psychologist here’s how I manage my worries about the coronavirus – Rappler

Are you checking your social media feed for coronavirus updates a lot? Did you buy toilet paper or rubbing alcohol more than you need? Are you wondering if you counted 20 seconds when washing your hands but forgot and so decided to start all over again? Are you giving the evil eye to that woman who didnt cover her mouth when she coughed? Did you flinch when she coughed? If youre fearful of catching the coronavirus, youre not alone.

My training as a clinical psychologist gave me the hands-on understanding of human behavior, including individual disorders. However, it was my training in public health, especially health policy, and later in psychiatric epidemiology that gave me the bird's eye view of how policy interventions at the sociocultural and systems levels can improve our mental health and wellbeing as a population.

Our individual worries about the virus is normal but can hurt others. We might feel some relief that we got a whole box of rubbing alcohol, but we forget that others need to clean their hands, too, for us to be protected. (READ: 'Customer not always right': Alcohol hoarders should be sent out of stores, says DTI)

Here are some ways I manage my own worries.

Yes, I am worried.

I admit to myself that I am nervous. I can feel a sense of impending panic. I am overthinking what may or may not happen. I am presenting at a conference in Tokyo later this month. Should I go? I was just invited to another one in Singapore in July. It might be better by then, right? My body feels tense. (READ: Questions Filipinos are asking about the coronavirus lockdown)

When I acknowledge these thoughts and feelings, I am able to manage the worries better and shift my attention towards something healthier.I know my strengths and vulnerabilities.

There is a lot we do not yet know about the coronavirus. Older people and people with severe underlying health conditions like heart disease, diabetes, and lung disease are at higher risk for the more serious symptoms of the illness.

So, I do feel some relief (though cautious) of my own risks. I am only in my late 30s, and according to a recent doctors visit, I seem to be in good health, although truth be told, I need to lose a bit of weight.

I am not immune to the virus, of course. It does not discriminate. But even the most basic information offers me some relief.

I get my news updates and then dont.

I only watch the news in the morning (before work) and at the end of the day (but not before bed). I might watch again in the middle of the day. I also watch at most the first 10-15 minutes and only at the top of the hour, when the most recent updates are likely to be broadcast. Then, I stop watching.

The news tends to recycle. It is the same every hour. The more I watch, the more I needlessly worry.

I limit my social media use.

I follow and rely on two sources the Philippine Department of Health (DOH) and the World Health Organization (WHO) Philippines. Thats it, no one else. You and many others (including this news organization) will post, share, like, etc., many other information, including those posted by the DOH and WHO. They will end up in my feed. For me, these are not helpful because you will have reinterpreted the original message in one way or another. Theyre noise.

I also deliberately unfollow 10 people (though were still friends) from my social media accounts. I do this every day. This limits how much and what kind of information I see. And these days, we get a lot of virus-related information. More details and statistics, more worries. I also turn off the comments or notifications. I rarely respond to comments, even positive ones. (READ: Staying compassionate in the time of coronavirus)

I do not share or like others posts regarding the virus. I do not want to add to the anxiety-focused algorithm.

My worries are softened with honest, simple, and forthright facts from reliable sources.

I reallocate my attention.

I become more anxious when I shift my attention to those things that are, well, anxiety-provoking, instead of those things that could offer me something more enjoyable or purposeful. I want to be more relaxed, but I am paying attention to things that dont make me feel that way. So, the more helpful solution is to reallocate my attention.

According to the WHO, most people (about 80%) recover from the disease, and they dont require special treatment. About 1 out of every 6 will develop serious symptoms, including difficulty breathing, but this also means 5 of them will not. Since the outbreak in December, the overwhelming majority of people have recuperated. Of the nearly 81,000 confirmed cases in China, nearly 62,000 have recovered. The odds seem to be in our favor.

I can choose to pay attention to the bad news and make myself miserable. Or I can shift that attention towards more hopeful things. I choose the latter, and I feel better.And finally, I stick to routine.

I do what I did even before the outbreak, as safely as possible. I run in the mornings but probably not as close to people. I go to my favorite caf but sit far away from others. The gym is less tempting these days, but there are a lot of online videos complete with attractive people who teach no-equipment workouts. Classes are suspended this week, but virtual learning is within reach perhaps to the disappointment of my students. A lot of my work can be done remotely.

I wash my hands. I use rubbing alcohol. I keep a distance. I eat as healthy as I can and drink plenty of water. I watch streaming videos, read books, and plan trips. I stay in touch with friends and loved ones.

I take deep breaths and say, This will pass. We will all be alright. Rappler.com

Dr Ronald Del Castillo is professor of psychology, public health, and social policy at the University of the Philippines Manila. The views here are his own.

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[OPINION] I'm a psychologist here's how I manage my worries about the coronavirus - Rappler

Opinion: Change your behavior now to prevent spread of COVID-19, implores Berkeley native quarantined in Italy – Berkeleyside

I am a Berkeley girl quarantined in Italy. Although the measures taken here are drastic, the coronavirus outbreak is not isolated in a distant paradise land of pizza and opera, but rather pressing on, inching closer to home each day.

Before moving to Italy, I lived my entire life in Berkeley. I am an alumna of Oxford Elementary, MLK Middle School, Berkeley High School and UC Berkeley. My Dansko clogs, Birkenstocks and mom jeans all came with me when I decided to take advantage of my Italian citizenship and explore life abroad to complete a masters in human rights, migration and development at the University of Bologna.

I moved a year ago with the specific goal to travel and create a strong international community. I travel by train for class, by plane for work, and by bus for everything else. An average week consists of dinner parties, aperitifs, concerts, art shows, lectures, coffee dates, teaching English in the local prison, museum visits, hikes, cultural festivals and picnics. There are always new adventures to other parts of Italy, to visit friends hometowns, explore hidden natural gems or see other expats.

Then, coronavirus landed. What started as an occasional dinner conversation turned, in a matter of weeks, to the most severe clampdown on personal freedoms in a European country since World War II. The quarantine is less dramatic than the American media outlets are portraying, yet simultaneously extremely serious and multifaceted. The series of unprecedented emergency measures published by the Italian government requires us to stay inside our homes. We cannot leave without a legally permissible reason like urgent work or grocery shopping and we are prohibited from gathering in groups. Parks, museums, cafes, restaurants and stores have been closed. Regulations are being implemented inconsistently dependent on regional autonomy. So, while I can still leave the house to take a short walk (with a permission document), friends in Milan are being stopped by police for trying to exercise that small freedom. For a country in which social lives are vibrant and present, where walks into the center of town are a normal daily activity, where public transportation is safe and works, this is a huge change. These measures, of course, pale in comparison to warfare and other horrors around the world but, as most people reading this and myself have spent most if not all their lives in the Global North, these events are unique and shocking.

While I write to give a greater understanding of my situation for friends and family back home, so many others are facing actual danger or harsher consequences. Some are just attempting like me to suddenly have to conceptualize a month at home while the sun is just beginning to peek out from behind the winter clouds. But I also have had many friends lose their jobs and fear deeply for their vulnerable elders or family with underlying health problems. Inmates in prisons are rioting because they are unable to see their loved ones. Six have died. Parents working from home are struggling to find or pay for childcare for kids whose schools have been closed. Others are unsure of when or how they will graduate from high school or university. Students who have been looking forward for years to a ceremony to celebrate their academic success, must defend their dissertations and graduate online. Funerals and weddings are canceled. Celebrations, birthdays and all other types of small and often forgettable privileges in life for 60 million people have been taken by this virus.

Yet more serious effects are still on the horizon. Small businesses are in crisis, stores and restaurants must close, and Italys already weak economy has a bleak forecast for the coming months. This comes as many are just getting back on their feet after the 2008 recession.

These new restrictive decrees were a response to the fact that, besides China, Italy has the most coronavirus cases with 15,113 confirmed and 1,016 deaths as of March 12. Coronavirus is not just a flu. Many need to be hospitalized for weeks in the ICU, yes especially the elderly and those with underlying health problems, but we have also seen those in their 30s and as young as 18 seek treatment. Theres a 14-day incubation period and we still have not reached the peak of cases. Even with these drastic measures, Italian hospitals are at capacity. In northern Italy, patients are being put in hallways because theres so little space. The government is considering converting warehouses into hospitals, and doctors, nurses and other medical staff are working nonstop. We do not have enough respirators for those most affected. Doctors are having to decide who out of the dozens of serious cases should be prioritized for a chance to live. The quarantine is drastic, but if Italy had not done everything in its power to stop the spread of the virus, this situation would have only gotten worse and the entire healthcare system would have completely collapsed.

Although coronavirus has put enormous stress on the country both financially and socially, unlike in the U.S., public health in Italy is viewed as a civic right and responsibility. What is often not in the headlines is that the high rate of cases is a result of Italys transparent reporting. Over 40,000 have been tested thanks to the accessible, universal Italian healthcare system. Although I feel the uncomfortable intrusion of the government, I have been humbled and inspired by the unity of the Italian people to sacrifice their freedom and economic growth for the protection of the most vulnerable in society. Italys restrictions, while harsh, have reflected a strong democracy as these laws are overall in alignment with the peoples will.

This quarantine foreshadows what is likely to become a more frequent part of life as climate change and other destabilizers will soon threaten us all in the same way that coronavirus has mutated Italy. Please do not view Italy, China or Iran as special cases. Germany, Japan and even home in the Bay Area are all experiencing outbreaks like that of Italys a few weeks ago. This is a global pandemic and I encourage you to take it seriously, yet also be wary of alarmist panic. Supermarkets do not need to be emptied and medical masks do not need to be bought. Wash your hands, reduce time in public spaces, stay home if you have any sort of fever and stop unnecessary travel.

This is not a post for the government or for administration, this is a plea from a Berkeley girl to all my fellow citizens in the Bay Area to act preemptively and change your behavior. It is everyones responsibility to mitigate the harm of this indiscriminate virus.

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Opinion: Change your behavior now to prevent spread of COVID-19, implores Berkeley native quarantined in Italy - Berkeleyside

Finding Connection and Resilience During the Coronavirus Pandemic – The New Yorker

Across the globe, a coronavirus culture is emerging, spontaneously and creatively, to deal with public fear, restrictions on daily life, and the tedious isolation of quarantine. This is a bad science-fiction movie that is real, Agustn Fuentes, an evolutionary anthropologist at the University of Notre Dame, told me, in a late-night discussion this week, about how COVID-19 may alter the human journey. He envisions a profound evolutionary process to insure the survival of the species as pandemics become more common. Its already visible.

What is so important to humanity is connection. The kind of quarantinesin New York and Seattle, and what will happen in thousands of other places in the United Stateswill require people to connect in other ways, he said. One of the amazing things about the human speciesonce harmless critters not much more than monkeys running aroundis that, over time, we have become very creative. Weve adapted to survive. Thats what people will rely on nowcoming up with incredibly imaginative ways to find connections even when theyre not in the same physical space together.

In these early days of the global pandemic, human creativity has centered largely on simple forms of relief and release. In China, the epicenter of the COVID-19 outbreak and a nation where almost eight hundred million people have experienced some form of lockdown, night clubs that were forced to shut their doors have turned to virtual cloud clubbing. Viewers can watch d.j. sets on streaming platforms and send in messages to be read live, to create the illusion that they are connected. The new reality show Home Karaoke Station features famous singers taking requests, engaging with viewers, and performingfrom self-quarantine in their own homes. Shuttered gyms have offered workout classes online or via the popular WeChat social-messaging app. Other Chinese people on WeChat created a group looking for love under lockdown. In one of the twenty-plus mass-quarantine centers in Wuhan, the megacity where this coronavirus first emerged, women have turned to karaoke to lift the spirits of sequestered groups. At night, echoes of Wuhan Jiayouor Stay Strong Wuhanhave been heard as Chinese shout encouragement at each other from their windows.

In Iran, another of the COVID-19 red zones, doctors and nursesindividually and in groupshave participated in a coronavirus dance challenge, posting videos of themselves dancing to lively music in hazmat suits. Other medical staff in quarantine serenaded each other or brought instruments to perform for sequestered patients. A third-grade teacher in Khuzestan Province improvised to keep her classes going online after schools were closed nationwide. Stuck at home, she used the side of her refrigerator as a whiteboard. With a blue marker, she wrote out the rules, with diagrams, to explain how to calculate the area of squares, rectangles, and triangles. A photo of her lesson went viral on Twitter.

Over time, the impact of the novel coronavirus may be so sweeping that it alters human rituals and behaviors that have evolved over millennia. This could change everything from the way we conduct our economy to our greeting and grieving rituals, Fuentes said. Weve had plenty of things thrown up at us before, although this is on an unprecedented scale.

One of the keys to stemming the Ebola epidemic in West Africa, between 2013 and 2016, was changing long-standing traditions about dealing with the dead, including touching a corpse before burial. In just one case, in 2014, twenty-eight people became ill with Ebola from the three-day funeral of a prominent pharmacist in Sierra Leone; eight later died. The Ebola virus causes a horrific death. You bleed all your fluids out, Terrence Deacon, a professor of biological anthropology at the University of California, Berkeley, told me. The worst thing you can do with Ebola is to touch the dead, because their bodies are filled with virus-filled fluids. People had to go in with guns to prevent families from interacting with their dead. Behavior changed; the epidemic eased.

Traditions develop because they fit the ecology and biology of the timesand get passed on because the people who do them are better off. The evolution of rituals has already begun in small waysnot congregating, not travelling, or attending meetings virtually. Around the world, many people have stopped shaking hands, a tradition that originated as a sign of trust but is now the most common way of transmitting the disease.

Were such a social species that its hard not to touch each other, Deacon said. So much of our communication is about touch. We dont have conventions about how to behave under circumstances like these. Well develop new cultural habits, new tricks, new mnemonics to get by. Were already experimenting. After the coronavirus outbreak, he attended a workshop of his peers at Stanford. People were bowing or touching elbows. We didnt know what to do, he said. But we knew we had to avoid shaking hands.

I asked Deacon if he thought COVID-19 would mark the end of the handshake. It could be, he replied. Behaviors are driven by the context. Shaking hands is about trust. If that behavior passes on a deadly virus, then it affects our trust markers.

Last week, Sylvie Briand, the director of the Department of Pandemic and Epidemic diseases at the World Health Organization, tweeted a cartoon of handshake alternatives, captioned the elbow, the Thai wai bow with hands together in front, and a sort of queenly wave. We need to adapt to this new disease, Briand wrote. In China, the so-called Wuhan shakea kind of foot-shake, tapping shoes togetheremerged initially in jest but soon in seriousness. At the ceremonial opening of a bridge in Tehran last month, the mayor and the provincial governor traded fist-bump gestures, coming close but not touching their hands.

In Europe, adaptations to COVID-19 even crept into Fashion Week last month. Giorgio Armani cancelled his show at Milan Fashion Week, and instead dbuted his winter collection from an empty theatre to an online audience. Even with no viewers, he opted to wear a face mask. At Paris Fashion Week, models for Marine Serre strode the catwalk in outfits with matching masks. Women in the front row of Dries Van Notens show were photographed wearing their own masks. In Croatia, the designer Zoran Aragovi, of the BiteMyStyle brand, created mask accessories in bright colors inspired by comic books, Pop art, and Disney characters. Theyre more fashion accessories than medical protection.

The need to adapt almost certainly will not end with a vaccine for COVID-19. The Darwinian story here is that we are in environments where these viruses mutate. The common cold is a coronavirus that keeps mutating. Viruses are evolution in actionon steroids, Deacon said. In the twenty-first century, changes in the pattern of human existencefrom global commerce and travel to climate changecould produce viruses that breed faster and move farther.

But Darwinian evolution is not necessarily all bad, Samuel Paul Veissire, an evolutionary anthropologist and the co-director of the Culture, Mind and Brain Program at McGill University, told me. Quarantines date to Neolithic timesand the transition from hunter-gathering to sedentary agricultural lifewhen zoonotic pathogens transferred from animals to humans produced infectious diseases and early epidemics. Communities eventually developed immunities to local diseases, but not to others nearby. Its quite possible that we evolved into being fearful of diseases and of strangers, he said. For millennia, people have been overly attentive to potential threats, because our psychological bias makes us assume that there are pathogens in other humans.

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Finding Connection and Resilience During the Coronavirus Pandemic - The New Yorker

Why do dozens of diseases wax and wane with the seasonsand will COVID-19? – Science Magazine

People seeking help for pandemic influenza in Brazil in July 2009, when cold weather boosted the spread of the disease.

By Jon CohenMar. 13, 2020 , 7:41 PM

On a December afternoon, 13 days before the winter solstice, six men and women checked into the Surrey Clinical Research Facility, part of the University of Surrey in the United Kingdom. After having their noses swabbed to check for 16 different respiratory viruses, they walked into their own temperature-regulated rooms and, for 24 hours, each person stayed in a semirecumbent position in dim light. Nurses placed a cannula into a vein of each persons arm, allowing easy sampling of blood that flowed through a tube to portals in the wall. The six subjects could press buzzers for bathroom breaks, where the stool and urine were collected, but otherwise, they were alone in the near-dark.

None of these people were sick. And although the shortest day of the year was approaching, their ritual had nothing to do with pagan rites, Yuletide traditions, or the annual hippie gathering at nearby Stonehenge to celebrate the rebirth of the Sun. Instead, they were paid volunteers in a study led by infectious disease ecologist Micaela Martinez of Columbia University to investigate a phenomenon recognized 2500 years ago by Hippocrates and Thucydides: Many infectious diseases are more common during specific seasons. Its a very old question, but its not very well studied, Martinez says.

Its also a question that has suddenly become more pressing because of the emergence of COVID-19. With SARS-CoV-2, the virus that causes the disease, now infecting more than 135,000 around the globe, some hope it might mimic influenza and abate as summer arrives in temperate regions of the Northern Hemisphere, where about half of the worlds population lives. U.S. President Donald Trump has expressed that hope repeatedly. Theres a theory that, in April, when it gets warmhistorically, that has been able to kill the virus, Trump said on 14 February. But whats known about other diseases doesnt offer much support for the idea that COVID-19 will suddenly disappear over the next few weeks.

Different diseases have different patterns. Some peak in early or late winter, others in spring, summer, or fall. Some diseases have different seasonal peaks depending on latitude. And many have no seasonal cycle at all. So no one knows whether SARS-CoV-2 will change its behavior come spring. I would caution over-interpreting that hypothesis, Nancy Messonnier, the point person for COVID-19 at the U.S. Centers for Disease Control and Prevention, said at a press conference on 12 February. If the seasons do affect SARS-CoV-2, it also could defy that pattern in this first year and keep spreading, because humanity has not had a chance to build immunity to it.

Even for well-known seasonal diseases, its not clear why they wax and wane during the calendar year. Its an absolute swine of a field, says Andrew Loudon, a chronobiologist at the University of Manchester. Investigating a hypothesis over several seasons can take 2 or 3 years. Postdocs can only get one experiment done and it can be a career killer, Loudon says. The field is also plagued by confounding variables. All kinds of things are seasonal, like Christmas shopping, says epidemiologist Scott Dowell, who heads vaccine development and surveillance at the Bill and Melinda Gates Foundation and in 2001 wrote a widely cited perspective that inspired Martinezs current study. And its easy to be misled by spurious correlations, Dowell says.

Despite the obstacles, researchers are testing a multitude of theories. Many focus on the relationships between the pathogen, the environment, and human behavior. Influenza, for example, might do better in winter because of factors such as humidity, temperature, people being closer together, or changes in diets and vitamin D levels. Martinez is studying another theory, which Dowells paper posited but didnt test: The human immune system may change with the seasons, becoming more resistant or more susceptible to different infections based on how much light our bodies experience.

Beyond the urgent question of what to expect with COVID-19, knowing what limits or promotes infectious diseases during particular times of year could point to new ways to prevent or treat them. Understanding seasonality could also inform disease surveillance, predictions, and the timing of vaccination campaigns. If we knew what suppressed influenza to summertime levels, that would be a lot more effective than any of the flu vaccines we have, Dowell says.

At least 68 infectious diseases are seasonal, according to a 2018 paper by Micaela Martinez of Columbia University. But theyre not in sync, and seasonality varies by location. In this graphic, based on U.S. federal and state health records, each bubble represents the percentage of annual cases that occurred in each month. (The data are old because many diseases declinedin some cases to zeroafter introduction of vaccines.)

(GRAPHIC) N. Desai/Science; (DATA) Project Tycho

Martinez becameinterested in seasonality when, as an undergraduate at the University of Alaska Southeast, she had a job tagging Arctic ringed seals, doing skin biopsies and tracking their daily and seasonal movements. While working on her Ph.D., her focus on seasonality shifted to polio, a much-feared summer disease before the advent of vaccines. (Outbreaks often led to the closing of swimming pools, which had virtually nothing to do with viral spread.) Polio seasonality in turn made her curious about other diseases. In 2018, she published The calendar of epidemics inPLOS Pathogens, which included a catalog of 68 diseases and their peculiar cycles.

Except in the equatorial regions, respiratory syncytial virus (RSV) is a winter disease, Martinez wrote, but chickenpox favors the spring. Rotavirus peaks in December or January in the U.S. Southwest, but in April and May in the Northeast. Genital herpes surges all over the country in the spring and summer, whereas tetanus favors midsummer; gonorrhea takes off in the summer and fall, and pertussis has a higher incidence from June through October. Syphilis does well in winter in China, but typhoid fever spikes there in July. Hepatitis C peaks in winter in India but in spring or summer in Egypt, China, and Mexico. Dry seasons are linked to Guinea worm disease and Lassa fever in Nigeria and hepatitis A in Brazil.

Seasonality is easiest to understand for diseases spread by insects that thrive during rainy seasons, such as African sleeping sickness, chikungunya, dengue, and river blindness. For most other infections, theres little rhyme or reason to the timing. Whats really amazing to me is that you can find a virus that peaks in almost every month of the year in the same environment in the same location, says Neal Nathanson, an emeritus virologist at the University of Pennsylvania Perelman School of Medicine. Thats really crazy if you think about it. To Nathanson, this variation suggests human activitysuch as children returning to school or people huddling indoors in cold weatherdoesnt drive seasonality. Most viruses get transmitted between kids, and under those circumstances, youd expect most of the viruses to be in sync, he says.

Nathanson suspects that, at least for viruses, their viability outside the human body is more important. The genetic material of some viruses is packaged not only in a capsid protein, but also in a membrane called an envelope, which is typically made of lipids. It interacts with host cells during the infection process and helps dodge immune attacks. Viruses with envelopes are more fragile and vulnerable to adverse conditions, Nathanson says, including, for example, summertime heat and dryness.

A 2018 study inScientific Reportssupports the idea. Virologist Sandeep Ramalingam at the University of Edinburgh and his colleagues analyzed the presence and seasonality of nine virusessome enveloped, some notin more than 36,000 respiratory samples taken over 6.5 years from people who sought medical care in their region. Enveloped viruses have a very, very definite seasonality, Ramalingam says.

In a study in New York and New Jersey, Micaela Martinez hopes to find out how artificial lighting affects the immune system.

RSV and human metapneumovirus both have an envelope, like the flu, and peak during the winter months. None of the three are present for more than one-third of the year. Rhinoviruses, the best-known cause of the common cold, lack an envelope andironicallyhave no particular affinity for cold weather:The study found them in respiratory samples on 84.7% of the days of the year and showed that they peak when children return to school from summer and spring holidays. Adenoviruses, another set of cold viruses, also lack an envelope and had a similar pattern, circulating over half the year.

Ramalingams team also studied the relationship between viral abundance and daily weather changes. Influenza and RSV both did best when the change in relative humidity over a 24-hour period was lower than the average (a 25% difference). Theres something about the lipid envelope thats more fragile when the humidity changes sharply, Ramalingam concludes.

Jeffrey Shaman, a climate geophysicist at Columbia, contends that what matters most is absolute humiditythe total amount of water vapor in a given volume of airand not relative humidity, which measures how close the air is to saturation. In a 2010 paper inPLOS Biology, Shaman and epidemiologist Marc Lipsitch of the Harvard T.H. Chan School of Public Health reported that drops in absolute humidity better explained the onset of influenza epidemics in the continental United States than relative humidity or temperature. And absolute humidity drops sharply in winter, because cold air holds less water vapor.

Why lower absolute humidity might favor some viruses remains unclear, however. Variables that could affect the viability of the viral membrane could include changes in osmotic pressure, evaporation rates, and pH, Shaman says. Once you get down to the brass tacks of it, we dont have an answer.

Will SARS-CoV-2, which has an envelope, prove fragile in spring and summer, when absolute and relative humidity climb? The most notorious of the other coronavirus diseases, SARS and Middle East respiratory syndrome (MERS), offer no clues. SARS emerged in late 2002 and was driven out of the human population in the summer of 2003 through intensive containment efforts. MERS sporadically jumps from camels to humans and has caused outbreaks in hospitals, but never widespread human-to-human transmission like COVID-19. Neither virus circulated for long enough, on a wide enough scale, for any seasonal cycle to emerge.

If we knew what suppressed influenza to summertime levels, that would be a lot more effective than any of the flu vaccines we have.

Four human coronaviruses that cause colds and other respiratory diseases are more revealing. Three have marked winter seasonality, with few or no detections in the summer, molecular biologist Kate Templeton, also at the University of Edinburgh, concluded in a 2010 analysis of 11,661 respiratory samples collected between 2006 and 2009. These three viruses essentially behave like the flu.

That does not mean COVID-19 will as well. The virus can clearly transmit in warm, humid climates: Singapore has more than 175 cases. Two new papers published on preprint servers this week come to opposite conclusions. One, co-authored by Lipsitch, looked at COVID-19 spread in 19 provinces across China, which ranged from cold and dry to tropical, and found sustained transmission everywhere. The second study concludes that sustainedtransmission appears to occur only in specific bands of the globe that have temperatures between 5C and 11C and 47% to 70% relative humidity.

In the final analysis, theres a balancing act between environmental factors and a populations immune system. The other coronaviruses have long been around, so a certain part of the population has immunity, which may help exile those viruses under unfavorable conditions. But thats not true for COVID-19. Even though there might be a big seasonal decline, if enough susceptible people are around, it can counter that and continue for a long time, Martinez says. Lipsitch doesnt think the virus will go poof in April either. Any slowdown is expected to be modest, and not enough to stop transmission on its own, he wrote in a recent blog post.

In Surrey, Martinez is investigating a different factor that might eventually affect COVID-19 incidence. Her subjects have returned to the clinic repeatedlyat the winter and summer solstices and again at the spring and autumn equinoxesso the researchers can evaluate how their immune system and other physiology change over the course of the day and from season to season.

She doesnt expect to show that our immunity is, say, weaker in the winter and stronger in the summer. But by counting different immune system cells, assessing metabolites and cytokines in the blood, deciphering the fecal microbiome, and measuring hormones, Martinezs team hopes to find that the seasons may restructure the immune system, making some types of cells more abundant in certain locales, and others less, in ways that influence our susceptibility to pathogens.

Animal studies support the idea that immunity changes with the seasons. Ornithologist Barbara Hall from the University of Groningen and her colleagues, for example, studied European stonechats, small songbirds that they caught and then bred in captivity. By taking multiple blood samples over the course of 1 year, they found that the birds ramp up their immune systems in the summer, but then tamp them down in the autumn, the time they migrate, presumably because migration is a big drain on their energy.

Melatonin, a hormone primarily secreted at night by the pineal gland, is a major driver of such changes. Melatonin keeps track of the time of day but is also a biological calendar for the seasons, says Randy Nelson, an endocrinologist at the University of West Virginia who specializes in circadian rhythms. When nights are long, more melatonin is released. The cells say, Oh, Im seeing quite a bit of melatonin, I know, its a winter night. In studies of Siberian hamsterswhich, unlike mice, are diurnalNelson and his co-workers have shown that administering melatonin or altering light patterns can change immune responses by up to 40%.

Seasonal changes in humidity, temperature, and other factors may affect the viability of viruses in droplets produced when people sneeze or cough.

The human immune system, too, seems to have an innate circadian rhythm. For instance, a vaccine trial in 276 adults by researchers at the University of Birmingham randomly assigned half to receive an influenza vaccine in the morning and the other half in the afternoon. Participants in the morning group had significantly higher antibody responses to two of the three flu strains in the vaccine, the researchers reported in 2016.

Theres evidence of seasonal variation in the actions of human immune genes as well. In a massive analysis of blood and tissue samples from more than 10,000 people in Europe, the United States, Gambia, and Australia, researchers at the University of Cambridge found some 4000 genes related to immune function that had seasonal expression profiles. In one German cohort, expression in white blood cells of nearly one in four genes in the entire genome differed by the seasons. Genes in the Northern Hemisphere tended to switch on when they were switched off south of the equator, and vice versa.

Just how these massive changes affect the bodys ability to fight pathogens is unclear, however, as immunologist Xaquin Castro Dopico and colleagues explain in a 2015 paper describing the findings. And some changes could be the result of an infection, instead of the cause. The team tried to eliminate people who had acute infections, but of course a seasonal infectious burden likely plays a part, says Dopico, who now is at the Karolinska Institute. And seasonal immunity changes could not explain all the complex variation in seasonality that diseases show. Theyre all out of sync with each other, Nathanson points out. Hes also skeptical that seasonal immune system changes could be large enough to make a difference. It would have to be pretty markedly different.

Martinez, however, says she has found intriguing hints. Early analyses from her Surrey study, which ended collecting data in December 2019, dont reveal anything about seasonality yet, but they do show that specific subsets of white blood cells that play central roles in immune system memory and response are elevated at certain times of day. She hopes to firm up the finding by launching a similar but larger study next year.

Martinez cautions, however, that artificial light may play havoc with the circadian rhythms that have evolved, with unpredictable effects on disease susceptibility. To explore possible impacts, Martinez has a separate study underway, with Helm, in both urban and rural parts of New York and New Jersey. They have installed light sensors on trees and poles and outfitted participants with devices that monitor light exposure and body temperature. The fact that people really are just kind of washing out the rhythms in light exposure can be problematic, she says.

Experiments of naturecould also offer insights into the factors affecting disease seasonality, Dowell suggested in his 2001 paper. People from the Southern and Northern Hemispheres who have adapted to different seasons regularly mix on cruise ships or at conventions, where they are confronted by the same pathogens. Witness the massive COVID-19 outbreak on thePrincess Diamond, which was docked and quarantined in Yokohama, Japan, for 2 weeks last month: Researchers could potentially analyze whether they were infected at different rates.

Whatever the answers, they might eventually bring important public health benefits, Martinez says. For example, If we know how best to administer vaccines, in terms of what time of year and the best time of day to take advantage of our immune systems, then we can get a lot more bang for our buck, she says.

The global COVID-19 emergency may bring more attention to the research and help speed discoveries, she says. But for now, no one knows whether rising humidity, the lengthening days, or some as-yet-unsuspected seasonal effect will come to the rescueor whether humanity must confront the pandemic without any help from the seasons.

Time will tell.

Link:
Why do dozens of diseases wax and wane with the seasonsand will COVID-19? - Science Magazine

Study connects specific genes with defective social behavior – Harvard Gazette

Animals rely on group behavior to survive, whether its fish swimming together to avoid predators or humans sharing knowledge with each other. But despite the importance of such social interactions, scientists do not have a good understanding of the biological processes that guide collective behavior.

In a new study published in iScience, researchers at Harvard University and the Max Planck Institute of Animal Behavior developed a new way to study how genes influence collective behavior. Using zebrafish as a model, they set out to establish the connection between genetic mutations and behavior.

We are interested in answering a fundamental biological question: why do animals live in groups? said Mark Fishman, Harvard professor of stem cell and regenerative biology. To search for genes that affect collective behavior, we focused on genetic mutations that are associated with psychiatric diseases that have a social behavior component, including autism and schizophrenia.

The team observed that in fish with specific genetic mutations associated with human psychiatric disease, group behavior was altered. The findings pave the way for a new generation of research into neuropsychiatric conditions such as bipolar disorder, autism, and depression.

The researchers tested 90 different genes to see if they affect zebrafish social behavior, using gene editing to mutate one gene at a time. For each genetic mutation, the researchers put the edited fish together in a large tank to see how they interacted with each other.

We used computer vision to track individual fish and analyze their interactions, said Fishman. By documenting how interactions change among the fish whether they get out of each others way, or whether they align with each other we could see how the overall pattern of group behavior changes.

The researchers found several genetic mutations that had a distinctive effect on fish group behavior. Normally, zebrafish spend much of their time in dynamically moving groups, called schools when all moving together in a coordinated fashion, and shoals when in less directed groups. Some mutations affected these groups, for example causing the fish to be scattered throughout the tank, or huddling together in one location.

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Study connects specific genes with defective social behavior - Harvard Gazette

Coronavirus: What we need to learn from the 1918 flu epidemic – Los Angeles Times

Its hard to believe weve devoted so little of our memory to something that killed 50 million people. Once in a while, the 1918 flu epidemic pops up like a plot point in the period TV drama Downton Abbey. But in an age before instant communications, and in the midst of that vast man-made meat grinder of death called World War I, our exhausted species buried the epidemic along with its dead. Yet with the coronavirus now on the move around the world, its worth resurrecting the 1918 pandemic to study ourselves then, know how we reacted to it, how we learned and didnt learn from it.

Laura Spinney is a science journalist whose book Pale Rider: The Spanish Flu of 1918 and How It Changed the World, gives us what we have forgotten or never knew about this illness that killed almost three times the 18 million victims of World War I. Many millions caught the Spanish flu but survived: the king of Spain, paradoxically; Mohandas K. Gandhi; Franklin Delano Roosevelt; and Walt Disney. When you think of our alternative history had they not survived, you get a sense of how life-altering this death tsunami was for the world.

*****

Are we seeing deja vu all over again for what was called the Spanish flu?

The Spanish flu is one of the worst, if not the worst, pandemics that humanity has ever known. And I think we should hope that this one is not that bad. Weve had many other pandemics, both of flu and of other diseases, that were not nearly as bad as the Spanish flu of 100 years ago.

So, yes, there are parallels, but I think we need to keep it within perspective.

What are some characteristics that we see in every one of these, about human behavior, human psychology, the disruptions to society and to economies?

An epidemic of infectious disease is something that brings us right down to earth. It kind of makes a mockery of all the ways that human beings like to divide themselves up, by class, by wealth, by color, by religion, because everybody is vulnerable.

For example, borders borders dont coincide with geographical frontiers, with oceans or mountains. Theyre lines on a map. Theyre ideas that some politician had. And viruses have no idea what that means, and they just walk across them.

What about our individual psychology?

Theres a lot of fear and some of that is reasonable. This is a disease that we dont yet understand. It looks to be more lethal than seasonal flu, and perhaps more contagious.

But I think that a big important issue here is information. And people will act sensibly and appropriately and proportionately if theyre properly informed. And we dont seem to be able to manage that information dimension of pandemic very well.

In 1918, for example, there was a big problem of wartime censorship, which blocked information getting out there.

And today we have a very different problem, which sort of comes to the same thing in the end, which is fake news. I think its a big problem in trying to inform people about this current outbreak and how best to manage it and behave in it.

As a lot of young people have pointed out to me, information tends to be locked behind paywalls these days, whereas fake news is free. And this is the attitude of people whove grown up with the internet: They dont expect to pay for their information. And so they get deluged with a lot of bad information. And I think that a lot of the kind of disproportionate behavior stems from that fact.

Information, weve learned, is absolutely crucial to managing an epidemic. You want people to comply with your public health measures voluntarily, because we know that mandatory health measures tend to be counterproductive. Theyre only going to do that if, A, they trust you, and B, you give them correct information. We have a massive problem of fake news, and that is going to be a major obstacle this time around.

Does peoples behavior alter, or are we at heart the same scared, selfish creatures weve been for thousands of years?

I think were the same inconsistent creatures weve been for thousands of years. In Europe, 40,000 people will probably die from seasonal flu this winter. Nobody is panicking about that. And in a sense, thats understandable, because we know a lot more about the flu. Theres a flu season every year. We sort of know what to expect.

Whereas we dont know what to expect from this coronavirus.

But in another way, it suggests that weve got things out of perspective. And I think that in some ways were very irrational and we react to the news cycle. If we could just draw back a little bit and see that HIV has been killing legions of people for decades. TB is on the rise because theres anti-microbial resistance, which means that the drugs arent working that well anymore. Childhood diseases are coming back largely because of vaccine hesitancy.

I mean, this could go very big, this coronavirus. But at the same time, its not the only problem, and we mustnt lose sight of the others.

What would it have been like to be alive and in your 20s in 1918 or 1919, when you were doing your daily business, whether it was going to the market or maybe going to the movies or taking a train to see a relative? How different did the world look with the flu afoot?

One thing that we cant overlook is that the world was at war. And so people in their 20s say, people between 20 to 40 were of conscriptable age and in many countries were active in the military.

The age group of 20 to 40 unfortunately was also very vulnerable to the Spanish flu for reasons that we only partly understand today. Daily life was rather traumatic at that time. Pregnant women were particularly vulnerable and had miscarriages in large numbers, and also died more commonly than people who werent pregnant and people in other age groups.

Everything I say has to come with the caveat that it depends where you were in the world, because this is a global phenomenon. But say were talking about the industrialized parts of the world: Those were the parts that were beginning to be used to the concept of public health campaigns, to the idea that governments could intervene in your private lives and tell you how to behave for the collective good of society. Wear a mask. Dont cough. Use a handkerchief.

Also it was a very much more obedient society in some ways. Doctors were far more paternalistic, and people were far more willing to do what the doctor told them without questioning it than they are today.

That was enhanced also by time of war. It was almost a patriotic duty to put your mask on and not shake hands and use a handkerchief and so on.

People were more likely to respond with mystical explanations in religion in 1918, to find religious explanations for what was happening to them. Psychologically, I think it was much easier even for people in supposedly advanced countries to try and find mystical explanations for this maybe divine punishment for this dreadful war.

Youre going to go to the church or the mosque, go to the synagogue and pray, which is probably not wise if it means that youre going into a crowd of other people. And indeed, you see that as were seeing in South Korea today, that gatherings in religious sects and so on in places of worship are accelerating the spread of the disease. And they did so in 1918 as well.

During the war, of course people would have had to sacrifice and pull together. Did that in any way prepare them to deal with this pandemic of flu? Because in your book, you write that your best chance of survival was to be selfish and guard your food and water and ignore all pleas for help, which seemed to work against the lets all pull together war effort of the previous four years.

What I was trying to say in the book was that logically, rationally, the best way to bring a pandemic or epidemic to an end quickly with the minimum number of casualties is that everybody isolate themselves because then the virus cant spread and it dies out.

But actually, and in some ways heartwarmingly though not very rationally, our instinct is to help each other. You see that very often people went to each others aid and not just family and friends, but also strangers.

Psychologists talk about something called collective resilience. They talk about the idea that when theres an external threat a disease of this kind, for example people start redefining themselves. The self is no longer the individual self. Its the collective self, because its everyone whos threatened by this external thing, and so people pull together as a collective self and they consider themselves all in the same boat.

And of course, it is antithetical to the idea of stopping the infection from spreading. But its a basic human instinct, for better or worse.

Over centuries, when diseases have appeared, blame has been assigned. Sometimes the Jews were blamed. Syphilis was called the French pox, if you werent French. In this case, the Spanish flu was not Spanish. This is an uglier aspect of disease and human nature.

It is the eternal human dilemma. Who is us and who is not us? Who is other and where is this threat coming from? And so the other side of human behavior that we tend to see in epidemics is this pointing of blame.

And were seeing it today with the coronavirus. There have been massive reports, spiking reports, of xenophobia directed at people of East Asian descent. During the plague outbreaks of the Middle Ages, Jews were very often blamed for poisoning the water in the wells, and expelled, and all sorts of other awful things happened to them.

This is a perennial and ugly side of human nature.

After the flu epidemic there were world-shaking political consequences.

When 50 million people die, or 2.5% of the human population, which is what were talking about, that is not negligible. That is going to have an impact.

If you take the example of South Africa, there were already the stirrings of what would become apartheid. There had been talk of segregating towns along color lines, but nothing had been translated into law. And you see that translation into law happening from the 1920s.

One of the arguments I made in my book, for which I think theres pretty good evidence, is that the epidemic gave a big spur to that legislation because white people blamed very explicitly black people for bringing in the disease without any evidence whatsoever. In fact the black population suffered much worse than the white population in terms of percentages in South Africa.

In India, when the pandemic struck, it became absolutely blatantly clear to everyone how dismally the British colonial authorities had provided for the healthcare of the indigenous population. People were dying in droves and in the absence of any British doctors the British doctors there were, were very often at the front as well the hole was even more glaring.

The people who stepped into that [medical] breach tended to be the militants, the grassroots militant activists for independence who had already worked out how to cross caste barriers and work together for a different goal, i.e. independence.

Once the pandemic passed, emotion against the British was even higher than it had been before. And secondly, those people were far more united than they had been. And now they came together behind Gandhi. He found that suddenly, he had the grassroots support that he had been lacking until then.

What about social changes within the family or a society?

Huge demographic changes. Often it was the pillars of the community, the breadwinners, who were being taken out. The few studies there are suggest that old people went in droves into workhouses because they no longer had any way of supporting themselves.

There were also millions of orphans created. Even in the most advanced countries of that time, there was no real social welfare net, no organized system of adoption. And so these people kind of just vanish.

Another interesting observation is that were talking about a time when the biggest killer of human beings was infectious disease. What it did as a result was to leave behind a smaller but in many ways healthier population, which now began to reproduce at a higher rate. So what you see in the 1920s is a baby boom.

If you look at humanity at the population level, its recovering from this huge disaster very, very quickly in a way.

When it comes to medicine and its ability to cope and its advances, wed had four years of very heroic battlefield medicine, but those techniques were exactly the opposite or inadequate when it would come to dealing with a pandemic. What came out of this in terms of medicine and public health?

Virus was a relatively new concept when the Spanish flu exploded, and once it had receded, I think doctors took a long, hard look at what they knew or more importantly, what they didnt know.

You see from the 1920s, the field of virology takes off, also the field of epidemiology, and epidemiology is the cornerstone of good public health.

You see the discussion around socialized healthcare, the idea of a universal healthcare system thats free at the point of delivery, start. Theyd already been ongoing for a couple of decades, but now they really start coming together.

And then the other really important thing is, is a global health agency. The League of Nations had a health branch essentially the forerunner of the World Health Organization, which was created in 1946.

Of course, its the World Health Organization that is managing the global response to this current outbreak. But what I think is interesting is that these days, the World Health Organization has less sway than it had in the past. Its chronically underfunded by its member nations. And many of them have ignored its recommendations during this outbreak.

Weve forgotten a lot of the lessons that we learned after the Spanish flu and other pandemics, and we may be about to learn them again.

When you watch the news, read the news, follow this, what are you watching for?

One of the things thats become clear about managing any epidemic is that they tend to grow very fast in the first weeks or months. You can think of it like a forest fire that initially, when it sparks is surrounded by dry wood and so it just takes off, and then it gradually burns up its fuel and it runs out of fuel and it slows down and gradually it burns itself out.

An epidemic is a little bit the same, in the sense that its initially surrounded by everybody susceptible. As it burns through those hosts, either kills them or leaves them to some extent immune, it runs out of hosts and so gradually burns out.

If you can slow down that initial pattern of growth, that initial period of growth, you can make a massive difference in terms of how many people will eventually suffer from this pandemic overall.

How are we doing?

In retrospect, I think the Chinese did an amazing job. We see now that the rate of new cases in China is slowed down dramatically. We shouldnt be complacent, but that is encouraging. That means that, OK, it took a certain authoritarian regime to enact it.

Did you have any episodes of this flu in your family history in 1918-19?

The grandfather of my stepdaughter. When he died, they renovated his farmhouse in the north of Sweden. They found a pack of love letters bricked up inside the wall. And it turned out they were love letters that hed written to his first wife, his beloved first wife, who died a few weeks after their marriage, in the summer of 1918, of the Spanish flu, and he ended up marrying her best friend, who was the grandmother of that whole branch of the family that survived.

It illustrates how to us, looking back, everything seems to have happened as it should have been. But there was a huge game of musical chairs that set in after the Spanish flu, and peoples families were rearranged. You didnt necessarily feel that you were married to the person you wanted to be or you were supposed to be. Life suddenly took a very different path and people had to adapt.

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Coronavirus: What we need to learn from the 1918 flu epidemic - Los Angeles Times

Trivially Speaking: Go back to 1976 to trace the origin of the meme – Loveland Reporter-Herald

Once in a while its not very often I encounter a new word. My English background and reading habits limit this meeting to only a few opportunities.

Recently, I did stumble on one that I first thought was simply a misspelling of memo. The word was meme.

In my prior gainful employment I read many memos and even wrote a few. As you would know, memo is just the short version of memorandum (from the Latin, It must be remembered).

Most of them even the ones I wrote werent of the must be remembered variety. I always believed that the Latin word was just in the wrong order; it should have been random memo. However, I digress.

Anyone who has held a job in a company, school district or government knows what a memo is (but Ill bet cant quote one from memory).

So when I went resource-fishing for meme I netted something entirely different.

If youre familiar with memes, hold up your hand and you can be excused from the rest of this column.

A meme is an idea, behavior or style that spreads by imitation from person to person within a culture.

This is where it gets tricky. Often the meme has the aim of carrying a particular theme or meaning. The meme is the vehicle for transmitting ideas, practices or symbols from one brain to another through writing, gesture, ritual or other imitable act with a mimicked theme.

Meme is a new word born in my 37th year.

The word had its birth in Richard Dawkins 1976 book The Selfish Gene.

Dawkins cited the work of three ologists as his inspiration. They were an anthropologist, an ethologist and a geneticist. The studies led him into the conclusion that evolution depended on the existence of a self-replicating unit of transmission in the case of biological evolution, the gene.

Thus to Dawkins, the meme was a self-replicating unit with relevance to explaining human behavior and cultural evolution.

He did coin the word meme and developed his meme theory, although the possibility that ideas were subject to similar pressures of evolution as were biological characteristics was noted during Darwins time.

Richard may have had some help in his choice of words.

Meme could be a shortening of mimeme, ancient Greek havent the modern Greeks made any contributions? for imitated thing.

Prior to its being identified as a meme we can consider the graffito, Kilroy Was Here! as qualifying. It became extremely popular in the 1940s, especially in the military. Then it existed under various names in other countries. Today its seen as one of the first widespread memes in the world.

Some observers have likened the transmission of memes to the spread of contagions.

The internet and its vehicles have eased the distribution of memes and many days one or two pop up in communications that pass by Trivially Speaking.

Even Twoey has picked up on memes. As he takes his constitutionals, he pauses to leave his version of Kilroy was here for other wandering canines.

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Trivially Speaking: Go back to 1976 to trace the origin of the meme - Loveland Reporter-Herald

How to keep calm in a pandemic: Education, information and communication – The Japan Times

As the coronavirus crisis continues to unfold worldwide and with no vaccine in sight, one thing prevails: uncertainty.

That has sent thousands of shoppers in Japan and abroad into a grocery-hoarding frenzy, including panic-buying of toilet paper and brawls over face masks.

But fears over the pandemic can be managed and psychologists and human behavior experts are calling for policymakers to be more transparent to help the public cope with distress over the outbreak and offer tips for navigating anxieties.

Why do people hoard toilet paper in a health emergency?

Japan was one of the first countries, after Hong Kong and Singapore, to see the coronavirus scare spark a number of false rumors on social media suggesting that toilet paper is expected to run out, spurring a consumer rush to stock up.

The Japan Household Paper Industry Association earlier in March assured the public that 98 percent of the countrys products were made domestically and thus there was no paper shortage in Japan.

Kazuhiro Goda, the associations director, believes the situation should soon get back to normal as long as consumers remain calm. But at the moment, many stores and supermarkets are still rationing goods as eerily empty shelves greet consumers in need of toilet paper.

Goda said that excessive purchasing of goods over a short period of time resulted in an instant shortage of toilet paper at many stores.

But makers do have plenty of stock, operate 24/7 and ship their products regularly. The thing is that distributors dont catch up with higher demand and thus stores havent re-stocked their shelves yet, waiting for delivery, he assured in a telephone interview Thursday.

Steven Taylor, a psychologist who has studied behaviors in crises, said, I think whats happening is toilet paper has become a symbol, a symbol of safety for some people.

In an interview Wednesday, the author of The Psychology of Pandemics described the tendency as an attempt to protect oneself from the virus as everyday things like hand-washing or covering ones mouth when coughing, as recommended by health experts, dont seem like enough.

But Taylor points out that panic-buying may continue even after stores restock their toilet paper supplies.

There will be panic buying of other things, he said.

David Savage, associate professor of behavioral economics at The University of Newcastle, Australia, compares panic-buying to a rush at a bank where individuals feel that the institution may be unable to release the individuals money due to some speculation.

What we observe with panic buying is based on incomplete information, due to uncertainty and a lack of knowledge in local conditions, he wrote in an email. But just like the runs of the bank, once started they are virtually impossible to stop.

What frightens us?

Savage believes that the general public is also dealing with ambiguity.

People do not know what it is that they do not know! he wrote. They are uncertain if or when the virus will spread to the region, they do not know if they themselves will be infected, which also means they do not know if they need to go into isolation and need several weeks worth of supplies.

Mafumi Usui, professor of social psychology at Niigata Seiryo University Faculty of Social Welfare and Psychology, said that fears in Japan have heightened to the point where some people exposed to daily doses of news on the coronavirus crisis wish to get infected soon.Amid alarming levels of spread, the World Health Organization on Thursday declared the coronavirus a global pandemic. By Friday, the number of confirmed COVID-19 cases had exceeded 120,000 and more than 4,300 people had died after contracting the virus.

But Usui believes the word pandemic wont spark more fear than the virus already has.

He said, however, that the anxieties may be associated with cultural norms and governments handling of the crisis.

In Japan, causing trouble to others frightens as much as the virus.

Many (Japanese) people fear theyll be the first in the area where they live, or their workplace, to contract it, Usui said. People dont want to stand out as these cases make headlines. And if they were first, many people would feel ashamed (of causing trouble).

The names of companies and establishments the patients had visited are disclosed in Japan.

What I think is actually occurring is not panic, but we are succumbing to several other behavioural issues, specifically herd behaviour and loss aversion (regret), Savage wrote.

When we see others acting in a certain way we have historical makeup that wants us to conform with the group. Or at the very least we stop and think about the behaviour and wonder if we should also be doing that.

Meanwhile, Taylor, a professor and clinical psychologist at the Department of Psychiatry at the University of British Columbia, pointed out that the situation surrounding the coronavirus may have an impact on specific groups of the population.

Those unknowns, theyre particularly difficult for people with the pre-existing history of anxiety problems, people who have a great deal of difficulty tolerating uncertainty, he said Wednesday.

What can policymakers do to ease public concerns?

What experts agree on is that the world needs competent leaders capable of delivering appropriate messages to their communities.

Usui believes that: In times of a crisis, the government and (health) officials need to effectively communicate risks but a good dialogue is based on trust and the government should also make effort in gaining it.

Usui stressed that the government should offer more advice on how to follow ones daily routine safely to ease the citizens fears and help them make rational decisions.

Weve heard (officials) urge the public to self-control or refrain from doing many things, as well as warnings of potential risks but Id like to hear more about whats relatively safe, he said.

Savage sees uncertainty and a lack of information as the true enemy in regard to public behavior, and stressed that unknowns perpetuate fear and create bias.

The best solution may well be as simple as public education campaigns delivered in the simplest way possible and framed in a positive light rather than a negative, he said.

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How to keep calm in a pandemic: Education, information and communication - The Japan Times

Spending less time on Facebook could boost your well-being and happiness – The Jakarta Post – Jakarta Post

New European research has found that spending just 20 minutes less time on Facebook each day could increase our happiness and healthy lifestyle habits.

Carried out by a team of psychologists from Ruhr-Universitt Bochum (RUB), Germany, the new study looked at 286 participants who used Facebook for an average of an hour each day.

Of these participants, 140 were asked to reduce their Facebook use by 20minutes each day over a two-week period, which is about one third of the average usage time, while the remaining 146 participants acted as the control group and carried on using Facebook as usual.

The participants were asked to complete questionnaires recording their Facebook use, their well-being (such as depressive symptoms) and their lifestyle (such as physical activity and smoking habits) before the start of the study, one week into it, at the end of the two weeks, and one month and three months after the study had finished.

The findings, published in the journalComputers in Human Behavior, showed that the participants who were told to reduce their Facebook usage time used the platform less, both actively and passively.

Read also: Spending money on experiences rather than possessions could bring you more happiness

"This is significant, because passive use in particular leads to people comparing themselves with others and thus experiencing envy and a reduction in psychological well-being," commented lead author Dr. Julia Brailovskaia.

In addition, those who used Facebook less were also significantly more physically active, smoked less, were significantly more satisfied with their life, showed significantly fewer symptoms of depression, and showed fewer symptoms of addiction to Facebook after the two weeks, compared to the control group. These positive effects could also still be seen three months after the study had ended.

"After the two-week period of Facebook detox, these effects, i.e., the improvement of well-being and a healthier lifestyle, lasted until the final checks three months after the experiment," said Dr. Brailovskaia, who added that the findings suggest that just reducing the amount of time we spend on Facebook each day could be enough to increase our well-being and prevent addiction.

"It's not necessary to give up the platform altogether," concludes Dr. Brailovskaia.

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Spending less time on Facebook could boost your well-being and happiness - The Jakarta Post - Jakarta Post