Category Archives: Genetics

Coronavirus: Genetic research and Covid-19 – Stuff.co.nz

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So what can Covid-19 remind us about grapevine genetics? The most obvious thing is risk.

OPINION: People tend to think of evolution as something that only happened in the past.

Say the word evolution, and it sparks images of our knuckle-dragging ancestors learning to walk upright and, eventually, to slouch over a computer.

With a wave of stories in recent days about Covid-19 virus mutations and a race for a vaccine -think again about evolution.

It's the continuous churn of diversity and competition that is central to life on our planet, and what we are seeing right now with Covid-19 is evolution in action.

This is no cause for alarm or panic, nor is it news for the global science community. Rather, it's a reminder that life's blueprints are constantly changing, whether humans can see it or not.

So with reports coming from all corners of the world about the growing number of virus strains as it incorrectly replicates its own RNA it begs a question. If a virus can do this, what else can? The answer is every living thing from grapevines to humans.

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With our wine industry based on millions of copies of just a few individual clones, any biosecurity risk could be potentially catastrophic.

It's the reason the DNA in your left hand is slightly different to your right hand. Whenever new cells are formed, DNA must be replicated and, sometimes, there are errors.

This is why, for example, red grapes occasionally appear on a Sauvignon Blanc vine the DNA sequence has naturally changed as cells divide and the vine grows.

Genetic changes in grapevines -in their natural environment -is what I investigate at Bragato Research Institute as part of our Grapevine Improvement Programme.

It's also the basis behind our new website called Odd Vine (oddvine.co.nz), where anyone can submit a photo of odd vines in their vineyards. In New Zealand, every grapevine clone we have is because someone noticed something odd growing in a vineyard and collected it.

So what can Covid-19 remind us about grapevine genetics? First, is about risk.

Covid researchers are now looking at the DNA of infected people to investigate why the virus attacks some individuals severely while other people are asymptomatic.

More than other nations, the New Zealand wine industry is based on millions of copies of just a few individual clones. Think about the risk this could pose in the wake of a challenge, such as climate change or a biosecurity risk, for example.

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The DNA of all living things constantly changes, and understanding this in relationship to other things will be key.

Secondly, the Covid-19 pandemic should remind us that genetics needs ongoing attention -and funding -even when we are not in a time of crisis.

There are two factors that influence how a vine grows and produces fruit: its genetics and its environment. As an industry, we spend a lot of time and money on the latter -irrigating, pruning, spraying and fertilising.

We'll even hire helicopters just to change the micro-environment for a few hours.In stark contrast, we have propagated the same clones for decades, almost all of which were selected for their performance in overseas climates. This practice puts the brakes on the natural genetic cycles of selection adaptation in our vines.

The Bragato Research Institute is driving the work to identify and provide vines with improved traits and resilience, enabling the protection and growth of the New Zealand wine industry for future generations.

While no-one expects grapevines or the Covid-19 virus to evolve beyond recognition in our lifetimes, I can guarantee one thing. The DNA of all living things will continue to change, whether or not humans can see it, benefit from it or are inconvenienced by it.

* Dr Lizamore is the Principal Scientist for Grapevine Improvement for the Blenheim-based Bragato Research Institute (bri.co.nz). He holds a PhD in Molecular Genetics and Genomics from Lincoln University, spending the past decade studying plant genetics, DNA sequencing and what -in the natural environment - causes grapevines to evolve.

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Coronavirus: Genetic research and Covid-19 - Stuff.co.nz

Premier Tech Growers and Consumers and Purplefarm Genetics Announce an Exclusive Strategic R&D Partnership – StreetInsider.com

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Premier Tech Growers and Consumers and Purplefarm Genetics Announce an Exclusive Strategic R&D Partnership - StreetInsider.com

Article on COVID-19 in Iceland in New England Journal of Medicine – Iceland Monitor

An article on the spread of the novel coronavirus in Iceland was published by the The New England Journal of Medicine yesterday. The authors are scientist at deCode Genetics and their colleagues at the Directorate of Health and at Landsptali National University Hospital, mbl.is reports.

At the website of deCode, the aim of the study is explained:

The aim of the study was to provide as comprehensive a view as possible of how the virus spreads in a population, in this case one of 360,000 and implementing early and aggressive testing, tracking and isolation measures to contain the epidemic.

The results show that roughly 0.8 percent of the population at large is infected with several strains or clades of the virus supporting the concern that silent carriers spread the disease.

This suggests that while the efforts of the public health system have been effective so far in mitigating the spread to date, more data, including massive population screening, will be key to informing efforts to contain the virus in Iceland in the long run.

In attempting to carefully map the molecular epidemiology of COVID-19 in Iceland we hope to provide the entire world with data to use in the collective global effort to curb the spread of the disease, Kri Stefnsson, CEO of deCode Genetics is quoted as saying.

Kri states that widespread screening (ten percent of the nation has already been tested for the virus) and measures taken by the Directorate of Health to slow the spread of the virus give a good example of how this dangerous pandemic can be fought.

General screening in Iceland by deCode began March 13, where anyone who wanted could sign up for screening. By March 31, 10,797 individuals had been tested, 87 of whom tested positive for the virus. Subsequently, 2,283 peoople, randomly chosen, were tested, with a similar result.

After that, a sequence analysis of 643 positive tests was done, showing that the first cases originated in Italy and Austria, but later on, transmissions were traced to other countries.

Currently, 291 mutations of the virus have been found in the country that have not been identified elsewhere, according to decode.com.

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Article on COVID-19 in Iceland in New England Journal of Medicine - Iceland Monitor

Human Genetics Market Size Analysis, Top Manufacturers, Shares, Growth Opportunities and Forecast to 2026 – Science In Me

New Jersey, United States:The new report has been added by Market Research Intellect to provide a detailed overview of the Human Genetics Market. The study will help to better understand the Human Genetics industry competitors, the sales channel, Human Genetics growth potential, potentially disruptive trends, Human Genetics industry product innovations and the value / volume of size market (regional / national level, Human Genetics- Industrial segments), market share of the best actors / products.

Information has been added to the report to provide a realistic view of the industry based on data from Human Genetics manufacturers, i.e. H. Shipping, price, sales, gross profit, business distribution, etc., SWOT analysis, consumer preference, current developments and trends, drivers and limiting factors, company profile, investment opportunities, analysis of the demand gap, market size value / volume, services and products, Porters five models , socio-economic factors, official regulations in the Human Genetics branch. Market participants can use the report to take a look at the future of the Human Genetics market and make significant changes to their operating style and marketing tactics in order to achieve sustainable growth.

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The report examines the competitive environment scenario observed with key players in Human Genetics sales, the profile of their business, their earnings, their sales, their business tactics, and the forecasting situations of the Human Genetics sales industry. According to studies, the Human Genetics sales market is very competitive and diverse due to global and local suppliers.

The Human Genetics Sales Market Report mainly contains the following Manufacturers:

Market Competition

The competitive landscape of the Human Genetics market is examined in detail in the report, with a focus on the latest developments, the future plans of the main players and the most important growth strategies that they have adopted. The analysts who compiled the report have created a portrait of almost all of the major players in the Human Genetics market, highlighting their key commercial aspects such as production, areas of activity and product portfolio. All companies analyzed in the report are examined on the basis of important factors such as market share, market growth, company size, production, sales and earnings.

Report Highlights

Assessment of sales channels

innovation trends

sustainability strategies

Niche market trends

Market entry analysis

market size and forecast

The geographic department provides data that give you an overview of the turnover of companies and sales figures for the growth activity Human Genetics for electrical meters. Here are the strengths of the geographic divisions: North America (United States, Canada and Mexico), Europe (Germany, Spain, France, Great Britain, Russia and Italy and more), Asia-Pacific (China, Japan, Korea, India and Southeast Asia) and more ), South America (Brazil, Argentina, Colombia), the Middle East and Africa (Saudi Arabia, United Arab Emirates, Egypt, Nigeria and South Africa) and ROW.

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Table of Content

1 Introduction of Human Genetics Market1.1 Overview of the Market1.2 Scope of Report1.3 Assumptions

2 Executive Summary

3 Research Methodology3.1 Data Mining3.2 Validation3.3 Primary Interviews3.4 List of Data Sources

4 Human Genetics Market Outlook4.1 Overview4.2 Market Dynamics4.2.1 Drivers4.2.2 Restraints4.2.3 Opportunities4.3 Porters Five Force Model4.4 Value Chain Analysis

5 Human Genetics Market, By Deployment Model5.1 Overview

6 Human Genetics Market, By Solution6.1 Overview

7 Human Genetics Market, By Vertical7.1 Overview

8 Human Genetics Market, By Geography8.1 Overview8.2 North America8.2.1 U.S.8.2.2 Canada8.2.3 Mexico8.3 Europe8.3.1 Germany8.3.2 U.K.8.3.3 France8.3.4 Rest of Europe8.4 Asia Pacific8.4.1 China8.4.2 Japan8.4.3 India8.4.4 Rest of Asia Pacific8.5 Rest of the World8.5.1 Latin America8.5.2 Middle East

9 Human Genetics Market Competitive Landscape9.1 Overview9.2 Company Market Ranking9.3 Key Development Strategies

10 Company Profiles10.1.1 Overview10.1.2 Financial Performance10.1.3 Product Outlook10.1.4 Key Developments

11 Appendix11.1 Related Research

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Tags: Human Genetics Market Size, Human Genetics Market Growth, Human Genetics Market Forecast, Human Genetics Market Analysis, Human Genetics Market Trends, Human Genetics Market

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Human Genetics Market Size Analysis, Top Manufacturers, Shares, Growth Opportunities and Forecast to 2026 - Science In Me

Sunrise Genetics

We use genomics to develop and establish Cannabis as a crop for food, medicine, bioenergy, and fiber. The best plants, and the products derived from them, originate from specific combinations of genes that give them superior qualities.

Through accelerated breeding efforts using genetic markers, we apply phenotypic and agronomic insight to produce the most comprehensive platform for creating legitimate, commercial-ready plants or varietal lines.

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Sunrise Genetics

Home – Delphi Genetics

Staby technology

Staby Technology can be used for protein expression, as well as for plasmid DNA product.

No need to use antibiotics in the production process, therefore meeting regulatory guidelines.

Scalable fermentation process, the stabilization technology is solelybased on genetics elements and is directly scalable. The process can easily be transferred from R&D to industrial scale fermentation.

Perfect plasmid stabilization, that can result in higher yields for expressed proteins and plasmid DNA.

Access to the Staby technology: the technology is available through customized services, strain adaptation & productions, and/or licensing.

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Home - Delphi Genetics

Total Livestock Genetics – TLG

At the forefront of animal genetics and reproduction technology, Total Livestock Genetics is committed to providing a link between evolving technologies and the commercial needs of producers, whilst maintaining optimum customer service.

Total Livestock Genetics (TLG) was formed in 1989 by Shane and Erin Ashworth in response to the need for an independent and professional semen and embryo collection service. Since that time, TLG has expanded its range of complementary services and now includes storage and despatch, import and export of genetic material, live animal export, as well as complete suite of reproductive services for equine and ovine clients.

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Total Livestock Genetics - TLG

New Generation Genetics Your Brown Swiss Leader

November 8, 2019

"Bull of the Season!" is back! During each season of the year, we will feature a different bull that is leaving an impact. Check out the story on DAREDEVIL, on his breeders and how he came about. Also, we will be featuring the Bull of the Season on Facebook throughout the year. During the bulls specific season, please share your daughters by using the hashtag #bulloftheseason.

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New Generation Genetics Your Brown Swiss Leader

Podcast: Nothing about me without meThe importance of involving patients in genomic research – Genetic Literacy Project

In this episode of Genetics Unzipped, recorded at the recent Festival of Genomics in London, Kat Arney finds out why its so important to make sure that both academic and commercial research studies are done with rather than on participants.

Research into genetic conditions relies on information from patients and their families, whether thats detailed health records or genomic data. As the tools and techniques for DNA and data analysis become cheaper and more organisations get in on this fast-growing field, its vital to make sure that the most valuable research resource human lives doesnt get overlooked in the rush.

Fiona Copelandis the chair of a support group for UK families affected by primary ciliary dyskinesia or PCD a rare genetic condition that affects the lungs and is the mother of two adult sons with the condition. Shes spent many years acting as a patient representative, engaging with academic and industry scientists looking to involve PCD patients in research into understanding and treating the condition. She explains what her role involves and shares her advice for how researchers can engage and involve patient groups more effectively. Her top tip? Dont make children cry!

Next Arney speaks with Patrick Short. Hes the CEO of Sano Genetics a Cambridge-based startup that aims to connect researchers with patients who want to take part in genomic research. While some companies using patients in research have come under scrutiny for poor handling of data and ethical compliance, Short is keen to help organizations do better and drive change in the fast-growing commercial genomics sector.

Finally, we hear from Shelley Simmonds, a disability rights campaigner and rare disease advocate whose son Fraser was initially given a diagnosis of Duchenne Muscular Dystrophy as a baby. When Fraser didnt seem to be progressing as might be expected for a child with the disease, she and her family got involved in Genomics Englands 100,000 Genomes Project in search of clarity but things turned out not to be quite so simple. Shelley talks what happens when the question Whats wrong with my child? has no answer.

Full transcript, links and references available online atGeneticsUnzipped.com

Genetics Unzippedis the podcast from the UKGenetics Society,presented by award-winning science communicator and biologistKat Arneyand produced byFirst Create the Media.Follow Kat on Twitter@Kat_Arney,Genetics Unzipped@geneticsunzip,and the Genetics Society at@GenSocUK

Listen to Genetics Unzipped onApple Podcasts(iTunes)Google Play,Spotify,orwherever you get your podcasts

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Podcast: Nothing about me without meThe importance of involving patients in genomic research - Genetic Literacy Project

Genetic Testing: Are Over-the-Counter Options Reliable? – Curetoday.com

An expert raises her concerns about direct-to-consumer testing and shares ways people can protect themselves.

In an interview with CURE, Lisa Schlager, vice president of public policy for Facing Our Risk of Cancer Empowered (FORCE) and a BRCA1 mutation carrier, discussed OTC genetic tests versus those provided by health care professionals and what consumers should keep in mind as they make health decisions.

CURE: What are the major differences between OTC genetic tests and those ordered by a physician or genetic counselor?

Schlager: Its like night and day. As an example, 23andMe has a component where you can opt to test for the BRCA mutations, although it looks for only three of the potentially thousands of BRCA mutations. The BRCA1 and BRCA2 gene mutations are associated with increased risk of breast, ovarian, prostate and pancreatic cancer, and some people are interested to know if they may have one of these mutations.

But when youre testing for only three of the potentially 5,000 mutations, and those three mutations are most commonly found in the Ashkenazi Jewish population, youre going to miss a lot of information. The fact that the Ashkenazi Jewish population is about 2% of the population in the United States means that 98% of the population in this country is unlikely to have those specific mutations.

If you were to go to a genetic counselor or a health care specialist with expertise in genetics, they would talk to you about your family history, determine which testing is most appropriate and probably give you a test that is much more expansive.

We must understand also that BRCA mutations are not the only mutations that cause an increased risk of cancer. We now have dozens of mutations with names like PALB2, CHEK2, ATM and Lynch syndrome. These are all mutations that cause increased cancer risk, and if you test for only the three BRCA mutations, youre really not getting good information about your potential risk.

How can consumers determine which OTC tests are reputable?

There have been a lot of reports in the media of people selling tests to unwitting consumers who dont realize who they are dealing with, who dont realize that theyre being duped out of their insurance or Medicare information. I think the important thing is that if you go to a qualified health care professional, they are more likely to steer you to a reputable genetic test. If youre going to do a test over the counter, look at it for what it is. Its kind of a fun thing, and it may provide you with some interesting information, but the best place to learn about health risks and health conditions is through a qualified health care professional or genetics counselor. Ultimately, if you do test positive for one of these health risks ... you need to confirm it with a health care provider anyway. The other thing to be aware of is that if something seems suspicious, go with your gut.

Should consumers be more aware of certain characteristics of these fraudulent tests?

Absolutely. (Be wary of) those that are making promises about coverage and that everyone is able to get it covered now, 100% free or no cost to you, or if they are aggressively marketing. We have seen people marketing these tests at health fairs and senior centers. Thats not a reputable way to do this. Thats not how health care is supposed to be done.

Some of these tests, such as 23andMe, have been approved by the Food and Drug Administration (FDA). What does this mean?

FDA approval means that the FDA has vetted it and determined that the test is in fact accurate for what it claims to do. The reality is that the vast majority of genetic tests are not FDA approved, they are CLIA (Clinical Laboratory Improvement Amendments) approved, which is a designation under the Centers for Medicare & Medicaid Services.

So, it comes down to knowing who is providing the test to you and making sure that the company, the test provider, the laboratory, is a reputable lab.

What is the biggest takeaway for consumers who are concerned about their risk?

Talk to a doctor that you have a relationship with and share your concerns. Most doctors will either have a mechanism for assessing risk in office or will refer you.

Ultimately, there is coverage for genetic testing for people who have a family history or personal cancer history. People dont need to turn to these less reliable tests to get the testing.

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Genetic Testing: Are Over-the-Counter Options Reliable? - Curetoday.com