Biochemist Marcos E. Ortega, a native of El Paso, Texas, studied how viruses replicate at the University of Colorado Denver and Health Sciences Center, where he earned a doctorate in biochemistry. Following postdoctoral fellowships at USC and Harvey Mudd College, he landed a teaching position in 2013 at Macalester College in St. Paul, Minnesota.

This fall semester, he joins Cal State Fullerton as an assistant professor of chemistry and biochemistry. Ortega also holds a bachelor's degree in chemistry from Grinnell College in Iowa.

"I chose to pursue a career in academia as I truly love the combination of teaching and research," said Ortega, who also speaks Spanish. "I wanted to pursue a path that allowed me to impact the community and students in a very personal way through teaching, mentoring, outreach and service work."

I was inspired to pursue biochemistry and education by two things: the passing of my grandfather from diabetes when I was a teen and the teaching career of my mother. When I chose to pursue chemistry in college, it was biochemistry and the molecular origins of disease that piqued my interest the most. I sought answers in biochemistry about diabetes, which helped me to deal with the loss of my grandfather. It was truly a case where knowledge was power, and I utilize these lessons to this day in my classes. I was also inspired by the patience and significant impact that my mom had on students as a first-grade teacher. I want to have that same type of impact on others and a career in academics married my desire to impact students with the molecular understanding and prevention of disease and infection.

My research interests lie in trying to understand viral infection and viral replication using biochemical techniques and studies. I seek to understand how biophysical and biochemical principles guide the spontaneous assembly of a mature virus in a host cell. At the core, I want to investigate how viruses replicate and assemble and thus cause infection by studying the relation between protein structure and function.

I hope students learn that biochemistry is important to all people and impacts our lives on a daily basis. I want students to find a personal connection to biochemistry that hopefully motivates them to learn more. I also want students to find their place in the world and realize the importance of education. I know all students will not pursue biochemistry or biophysics, but through my teaching, I want students to know that anything is possible with a strong work ethic and an education.

I would like people to know that the answers to many of the difficult questions in todays world may be right in front of us. Whether its treatments for cancer, feeding the hungry, environmental issues or sustainable energy, the foundations of cellular function and the chemistry that drives it may begin to illuminate some answers that will help us prosper and advance as a society.

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Biochemist Studies How Viruses Replicate, Cause Infection - CSUF News

Michigan State Universitys Robert Last studies tomatoes. Specifically, he researches their hair, or trichomes.

For this study, he focused on a single type of molecule in trichomes acylsugars. The secrets Last and a team of MSU scientists found from studying these specialized metabolites open an evolutionary window for the emerging field of plant defense metabolism, insights that could lead to engineering advances for better pest resistance and human medicine.

There are an estimated 300,000 species of plants in the world, producing roughly more than a million metabolites. Plants use these molecules to grow, communicate with each other or to defend themselves against pests and disease. Humans benefit from many of these products for food, medicines and industrial uses. Thousands of core metabolites are found in every plant, but hundreds of thousands are more specialized and found only in specific groups of plants.

Acylsugars are an example of a group of specialized metabolites found only in the Solanaceae family, which includes tomato and petunia plants. These specialized metabolites have a wide variety of structures and are made by different enzymes working together to carry out a series of biochemical reactions.

We sought to understand how this novel pathway originated and diversified across 100 million years of plant evolution, said Last, MSU Barnett Rosenberg Professor of Biochemistry and Molecular Biology and Plant Biology and the studys senior author. This is our crystal ball, our view into evolution.

The crystal ball revealed that many of the enzymes that make acylsugars are promiscuous, meaning that they could use a variety of molecules as starting points for their chemical reactions. This could be the key as to how the plants make a variety of acylsugars.

The scientists also discovered that many of the enzymes that make acylsugars are encoded by genes that were originally copies of other genes and that have subsequently evolved new roles.

Deciphering these codes are important because tomatoes acylsugars are natural pesticides. Engineering plants to produce acylsugars could reduce pesticide use in crop production. Additionally, some of these mechanisms could help make chemicals that have pharmaceutical value, including ones that treat cancer and heart conditions.

Plants are master chemists, and were only just beginning to understand the metabolic pathways that they use to produce these amazing compounds, said Last, whos also an MSU AgBioResearch scientist. By understanding how the pathways evolved to produce these enzymes could lead to innovative ways to make valuable compounds on a large scale.

The MSU team of scientists contributing to this research included Gaurav Moghe, Bryan Leong, Steven Hurney and Daniel Jones. The paper is published in the current issue of the journal eLife.

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Tomatoes' 'Crystal Ball' Reveals Evolutionary Secrets - Laboratory Equipment

by Erin Facer | Wednesday, Aug. 30, 2017, 11:54 AM

Carlos Lopez (Vanderbilt University)

Carlos F. Lopez, assistant professor of biochemistry and biomedical informatics, has been appointed as Vanderbilt Universitys liaison to Oak Ridge National Laboratory, the U.S. Department of Energys largest science and energy laboratory conducting research in energy and security. Lopez will continue the many collaborations that Greg Walker, associate professor of mechanical engineering, initiated during his term in this role.

Carlos expertise at the interface of physical, biological and computer sciences is precisely what is needed to help Vanderbilt University develop closer scientific collaborations with Oak Ridge National Lab, Vice Provost for Research Padma Raghavan said. I am grateful to him for stepping into this role, and I look forward to working with him to further develop this important partnership.

Carlos is an energetic and interactive investigator who already has productive collaborations with Oak Ridge scientists. He is very well suited for this new role, added Larry Marnett, dean of basic sciences at the School of Medicine.

As the Vanderbilt liaison to ORNL, Lopez will work closely with Vanderbilt faculty, the Office of the Provost, university deans and Vanderbilt University Medical Center leadership to advance key research themes that align with both Vanderbilt and ORNL priorities.

I would like to be instrumental in bringing together researchers from both institutions to develop robust collaborations to accelerate discovery, Lopez said.

Lopez received his Ph.D. in physical chemistry from the University of Pennsylvania. He pursued a postdoctoral fellowship at the University of Texas at Austin, where he studied theoretical biophysics, and followed this with a postdoctoral position at Harvard Medical School. He moved to Vanderbilt University School of Medicine in late 2012 as an assistant professor of cancer biology. His work develops and applies novel computational modeling tools and leverages strong experimental collaborations to describe intracellular biochemical signaling networks to further our understanding of cellular decision-making processes.

Media Inquiries: Erin Facer, erin.facer@vanderbilt.edu

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Lopez named Vanderbilt's liaison to Oak Ridge National Laboratory - Vanderbilt University News

Taipei, Aug. 30 (CNA) Taiwan's Tang Prize Foundation announced Wednesday that it had formed a partnership with International Union of Biochemistry and Molecular Biology (IUBMB) in promoting the advancement of biopharmaceutical science Education.

The foundation signed a 9-year partnership project agreement with IUBMB in 2016 which is currently on the move, according to a statement issued by the organization.

Chern Jenn-chuan (), chief executive of the foundation, said in the statement that IUBMB plays a significant role in uniting researchers and scientists in the fields of biochemistry and molecular biology from 77 countries.

The cooperation project with IUBMB marked another step forward by the foundation in promoting the biopharmaceutical science education after it signed a memorandum of cooperation that established a 10-year partnership with the Experimental Biology (EB) in 2015, the statement said.

The EB, an annual gathering of professional research scientists, is sponsored by six societies: American Association of Anatomists (AAA), the American Physiological Society (APS), American Society for Biochemistry and Molecular Biology (ASBMB), American Society for Investigative Pathology (ASIP), American Society for Nutrition (ASN), and American Society for Pharmacology and Experimental Therapeutics (ASPET).

Furthermore, the Tang Prize Foundation will support outstanding young scientists to attend the "New Horizons in Biochemistry and Molecular Biology Education" conference which will be held Sept. 6-8 in Israel, it said.

The conference will be coorganized by the Weizmann Institute of Science (WIS) of Israel, IUBMB and the Federation of European Biochemical Societies (FEBS), the statement said.

Taiwanese chemist Andrew Wang (), president-elect of IUBMB who serves as the distinguished visiting chair of the Institute of Biological Chemistry at Academia Sinica, Taiwan's top academic research institution, will also attend the conference which is aimed at providing a think tank setting that can bring inspiration to the teaching of biochemistry and molecular biology, it added.

The conference will be followed by the FEBS 2017 congress which will take place Sept. 10-14 in Jerusalem, the foundation said.

Feng Zhang (), one of the 2016 Tang Prize winners in Biopharmaceutical Science, is to host a Tang Prize/IUBMB lecture in the conference on Sept. 12 on the topic "From Microbial Immunity to Genome Editing."

Zhang shared the Tang Prize with Emmanuelle Charpentier of France and Jennifer Doudna of the United States for the development of CRISPR/Cas9 as a breakthrough genome editing platform that promises to revolutionize biochemical research and disease treatment.

The cooperation between the Tang Prize and the world's top research organizations not only promotes awareness of the Prize in biopharmaceutical ccience but also encourages education and technology exchange in the Prize's four fields.

The Tang Prize awards were established by Taiwanese entrepreneur Samuel Yin () in 2012 to honor people who have made significant contributions in the fields of sustainable development, biopharmaceutical science, sinology and rule of law. They are dubbed as the "Asian Nobel Prize."

(By Romulo Huang) Enditem/sc

Originally posted here:
Tang Prize Foundation, IUBMB cooperate in promoting science education - Focus Taiwan News Channel

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Biochemistry Analyzers Market Overview, Industry Top Manufactures, Market Size, Industry Growth Analysis & Forecast ... - DailyNewsKs

Dr. Sharifa Love-Rutledge is a new faculty member in the UAH College of Science.

Michael Mercier | UAH

Sharifa Love-Rutledge developed a keen interest in science when she and her younger brother shared a lab kit for Christmas one year. "We made borax (super bouncy) balls first, and went on to complete all the experiments in the kit, and I wanted to do more," said Love-Rutledge, an incoming faculty member at The University of Alabama in Huntsville (UAH) College of Science. She is also the first African-American woman to earn a PhD from The University of Alabama Department of Chemistry.

When Love-Rutledge entered college, she started out as a biology major, but after completing general chemistry and organic chemistry courses, she made the "switch" to chemistry.

"I was drawn to chemistry because of my love for creative problem-solving. Biochemistry was the subject that allowed me to utilize my analytical thought processes to pursue biological questions. It didn't dawn on me that chemistry was a male dominated field until graduate school. By then, it was too late because I was already hooked."

A native of Moss Point, MS, Love-Rutledge attended Moss Point High School. An Advanced Placement student in English and Mathematics, she went on to graduate from Tougaloo College (Tougaloo, MS) with a Bachelor of Science degree in Chemistry. Love-Rutledge earned a Master's degree and PhD from The University of Alabama (UA) in Chemistry and Biochemistry, respectively.

Love-Rutledge said she "felt hopeful," when she realized she would be the first African American woman to earn a PhD in chemistry from UA. "It was bittersweet because the reality of it all is that I wasn't the first African American female capable of the accomplishment but opportunities weren't afforded in the past. It allowed me to view myself as part of the culmination of the sacrifices made by those like Vivian Malone and James Hood," she added.

The student in lockstep with Love-Rutledge in the Department of Chemistry at UA was Dr. Melody Kelley, now Assistant Professor of Chemistry at Georgia State University. Love-Rutledge said she continues to find "inspiration in seeing other African American women who are persevering and making progress toward the completion of advanced degrees."

Early mentors for Love-Rutledge were her older siblings. "They poured their knowledge into me to ensure that I made wise decisions. If it wasn't for my older brother, I don't think I would've survived some of my math courses," she said. "Once I left home, I started to rely on advice from my uncle Dr. Claude McGowan, who was Director of Toxicology at Johnson & Johnson, along with professors like Dr. Candice Love-Jackson, Acting Provost and Vice President for Academic Affairs at Kentucky State University."

Additionally, Love-Rutledge was encouraged through the graduate school application process by dedicated Ronald McNair Scholars Coordinator, Demetria Hereford. And, as a graduate student, she was able to enlist the tutelage of several professors at UA. "It was also in graduate school that I was reminded of how important my parents' guidance is. Their constant support and dedication was important in forming my personal and professional abilities."

Love-Rutledge learned about UAH from Dr. Emanuel Waddell, Associate Dean of the College of Science while attending graduate school at UA. "The deciding factors for me to further my teaching and research career at UAH included the size of the student population and access to resources that I would need to be successful. I have always wanted to work at a university where students are viewed as more than numbers."

"We are excited to have Dr. Love-Rutledge join us in the chemistry department. Her research will be attractive to students and we look forward to her establishing her research laboratory in the coming months," said Dr. Emanuel Waddell, Associate Dean of the UAH College of Science.

At UAH Love-Rutledge will teach biochemistry classes. "I have a lab and I am currently working on research projects related to identifying biomarkers for Type 1 Diabetes, and studying the changes cells producing insulin undergo before disease onset." As a teacher, Love-Rutledge said she loves students' lightbulb moments the best. At UA she served as a graduate teaching assistant for the majority of her graduate career. "I love reaffirming students' passion for their chosen field of study. There is no greater joy for me than to see my students go on to be successful in their fields of choice. I have taught students who wanted to be nurses and are nurses now, and students who wanted to be doctors who are now in residency programs. I love seeing students reach their goals."

As a Ronald E. McNair Scholar, Love-Rutledge's first bona fide research project studied the enzymes that activate colon cancer drugs. The project's Principal Investigator was Dr. Randy Wadkins, Associate Professor of Chemistry and Biochemistry at The University of Mississippi. "In my graduate research, I worked on projects that helped show Chromium, (hard, brittle metal) is not an essential element for mammalian nutrition. The research findings were published in a paper that led The European Food and Safety Authority to remove Chromium from the list of elements that 'require daily intake'."

Love-Rutledge freely offers words of wisdom for young women interested in entering academic fields of specialization. "Recently Ive been exposed to the slogan, 'You cant do UAH alone'. I think it's awesome advice for young women to adapt who are interested in chemistry 'You cant do Chemistry alone'," she said. "Even when you seem alone, you never are. Find mentors to give you advice, utilize your peers on and off campus to get through the tough times. Some of my best academic advice came from taking a risk and emailing a professor who I thought was out of reach. You will be surprised at how much help you could receive if you just ask for it."

***EDITOR'S NOTE: The McNair Scholars Program is a federal program funded at 51 institutions across the United States and Puerto Rico by the U.S. Department of Education. It is designed to prepare undergraduate students for doctoral studies through involvement in research and other scholarly activities. Dr. Ronald E. McNair was the second African American to fly in space. Two years later he was selected to serve as mission specialist aboard the ill-fated U.S. Challenger space shuttle. He was killed on Jan. 28, 1986, instantly when the Challenger exploded one minute, 13 seconds after it was launched.

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UAH welcomes Dr. Sharifa Love-Rutledge to the College of Science - UAH News (press release)

Taipei, Aug. 28 (CNA) Antibody and small molecule drugs and big data applications will remain at the center of biomedical research in the future, according to Andrew Wang (), president-elect of the International Union of Biochemistry and Molecular Biology (IUBMB).

Wang was speaking on the future development of biomedical technology in a recent interview with CNA, in which he encouraged local scientists to find the right directions if they decide to devote themselves to antibody drug research and development.

Biomedicine is an emerging sector that has attracted many scientists around the world, said the chemist, who serves as the distinguished visiting chair of the Institute of Biological Chemistry at Academia Sinica, Taiwan's top academic research institution.

Wang also encouraged researchers to seek new techniques, citing the example of French scientist Emmanuelle Charpentier and Americans Jennifer A. Doudna and Feng Zhang (), the trio who shared the 2016 Tang Prize for biopharmaceutical science.

They were honored for the development of the CRISPR/Cas9, a genome editing tool that enables geneticists and medical researchers to edit DNA, using a technique that has the potential for a wide range of applications, according to the Tang Prize Foundation.

Wang praised the CRISPR/Cas9 as a big breakthrough, and he expected it to significantly affect future research, which he said could even reach the aspect of biological transformation.

"In the future, cell therapies will become very important," Wang said.

In addition to antibody and small molecule drug research, changes in medical treatment methods are a direction that local scientists can also turn to, Wang said, noting that the results of big data analysis related to health insurance practices can be applied in the precision medicine sector.

The Tang Prize awards were established by Taiwanese entrepreneur Samuel Yin () in 2012 to honor people who have made significant contributions in the fields of sustainable development, biopharmaceutical science, sinology and rule of law. They are dubbed as the "Asian Nobel Prize."

The IUBMB is an international non-governmental organization concerned with biochemistry and molecular biology. Founded in 1955, it unites biochemists and molecular biologists in 75 countries that belong to the union as an adhering body or associate adhering body represented by a biochemical society, a national research council or an academy of sciences.

(By Yu Hsiao-han and Elizabeth Hsu)Enditem/sc

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Scientist expects biomed research to remain focused on antibodies - Focus Taiwan News Channel

Madeleine Gerrie of Sydney has been named this years recipient of the Sara March Memorial Educational Award handed out by the United Heritage Church in Sydney. Gerrie, who is studying biochemistry at Waterloo University, is shown with her younger sister, Naomi.

Submitted photo/Madeleine Gerrie

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Sydney student receives Sara March bursary - Cape Breton Post

Palestinian cancer patients in Gaza City protest Israels restrictions on travel for treatment, December 2016. Such restrictions are partly why academics are calling on colleagues to boycott Septembers Federation of European Biochemical Societies conference in Jerusalem.

Palestinian, Israeli and international academics are urging colleagues to boycott the 2017 congress of the Federation of European Biochemical Societies in Jerusalem next month.

Some attendees will be unaware of Israels direct attacks on Palestinians right to education, including the bombing of schools and universities, and the obstruction of access to educational sites, the scientists and academics write in a letter that has been sent to all conference speakers.

The restrictions Israel places on the teaching and research of our Palestinian colleagues have severe consequences not only on research and educational opportunities, but also on Palestinians health.

The 89 scholars calling for the boycott include researchers from leading institutions across Europe and North America.

Even though no country recognizes Israels claim to sovereignty over Jerusalem, the Federation of European Biochemical Societies conference website prominently advertises its location as Jerusalem, Israel.

It also locates the occupied Golan Heights Syrian territory as part of Israel.

Whether intentional or not, this makes the academic body a direct participant in Israels efforts to legitimize its violent occupation, annexation and colonization of these territories in violation of international law.

The conference is sponsored by several Israeli universities that are directly complicit in Israeli violations of Palestinian rights, including weapons development, support for Israels attacks on Gaza and helping recruitment for Israels secret police.

Israeli universities are also directly involved in efforts to undermine international solidarity for Palestinian rights.

The Association of University Heads of Israel, for instance, is known to help the Israeli governments efforts to censor teaching about Palestine in universities in other countries and to try to thwart the global Palestinian rights movement.

One of the themes of the conference is the biochemistry of cancer. Rates of cancer are rising, particularly for Palestinians in the blockaded Gaza Strip.

But as the scholars point out, Israel actively obstructs life-saving treatment: The five-year survival rate for breast cancer is as low as 30 percent in Gaza, which Israel has besieged for the past 10 years, as compared to 86 percent in Israel. In 2016, only 44 percent of Gaza patients who requested access to Israeli hospitals were admitted; more than half of those refused entry were cancer patients.

Meanwhile, the health system in Gaza is at the brink of collapse due to Israels severe reductions in the energy supply to the territory.

Anticipating typical arguments against the boycott, the scholars state: To be clear, the academic boycott of Israel that Palestinians have called for respects the universal principle of academic freedom as it is only directed at Israeli institutions, not individual academics. Despite the differences, it is inspired by the academic boycott of South Africa, which was called for in 1965 by 496 academics from 34 universities in the United Kingdom.

Last year, after a similar appeal, several scholars pulled out of a conference on genocide hosted by Hebrew University.

Israeli university leaders have said that they are being hit hard by a silent boycott, where many academics stay away from Israeli institutions but do not make any public statement.

Leading Israel lobby groups have also acknowledged the growing impact of the so-called silent boycott.

The scholars note that the Federation of European Biochemical Societies has itself been sensitive to political concerns regarding the location of its conferences. In 2016, the body expressed solidarity with the Turkish scientific community facing curtailment of academic freedoms in Turkey, and subsequently canceled its conference scheduled to take place there.

By organizing its congress in Jerusalem, the FEBS participates consciously or unconsciously in whitewashing Israels violent repression of Palestinian human rights, said Ahmed Abbes, research director at Frances CNRS scientific institute, and secretary of AURDIP, an academic group that supports Palestinians rights.

We hope that our colleagues will take the opportunity of consulting their consciences, listen to the voice of Palestinian civil society, and decline to cross this picket line.

Originally posted here:
Scientists urged to boycott Israel biochemistry conference - The Electronic Intifada (blog)

Biochemistry - Part I Moof UniversityMoof University Acids, Bases, and the Henderson-Hasselbalch EquationAmino AcidsProtein Structure and FunctionCarbohydratesEnzymesEnzyme InhibitionEnzyme RegulationBiochemist's Toolbox - Learn These BEFORE Learning Glycolysis and Other PathwaysGlycolysisGluconeogenesisGlycogenTCA / Krebs / Citric Acid CycleGlycolysis Energy CalculationsElectron Transport ChainPhotosynthesisPentose Phosphate PathwayLipidsFatty Acid MetabolismKetone BodiesFatty Acid SynthesisLipid SynthesisCholesterol SynthesisRegulation of Cholesterol SynthesisLipoproteins

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Biochemistry - Part I Moof University