From the dreadful study experience in Ekiti State to receiving the highest honour awarded to a graduating Ph.D. student at the Oklahoma State University, Babajide speaks on how he conquered the odds and rose to become an outstanding student with multiple awards.

Thirty-one-year-old Babajide Ojo has a Bachelors Degree in Biochemistry at Ekiti State University (EKSU) but his pursuit for richer knowledge made him proceed to Oklahoma State University (OSU) in the United States of America.

Recounting his experience while in EKSU, Ojo said it was a fun and challenging experience especially as a science student who was continually loaded with theories but with minimal hands-on laboratory experience.

I understand this was not entirely the fault of the staff as they could only use what was made available to them at the time due to inadequate funding.

Nevertheless, the final year project and writing experience I had with my supervisor, Professor (Mrs.) F.L Oyetayo was very instrumental to my experience and decision to pursue a graduate degree in an area related to nutritional biochemistry, Ojo said.

Other factors that made learning dreadful for him in Nigeria include the studying conditions marred by the epileptic power supply.

Studying conditions were dreadful at the time, as we usually lacked electricity and had to study in the lecture theatres at night using candles. No one deserves to study under those conditions and I can only hope the situation has improved.

Ojo is passionate about understanding how certain foods and nutrients interact with the beneficial bacteria in human intestines, and the implications on the prevention and management of type 2 diabetes markers.

All humans live with millions of bacteria in our intestines. These bacteria were recently shown to play an important role in the initiation or prevention of several diseases, including type 2 diabetes induced by obesity, he said.

Since obesity is an epidemic in both developed and developing countries, his hope is that identifying nutrients that benefit the human intestinal bacteria will assist in the management of obesity-related diseases such as type 2 diabetes.

His dissertation also sought to understand how supplementing a western diet with whole foods may improve outcomes of diet-induced obesity and type 2 diabetes by modulating the intestinal bacteria and immune system.

Interestingly, the United States Department of Agriculture took an interest in his findings during the research and sponsored further studies that are currently ongoing in humans.

Ojo may not be able to speak for all US or Nigerian students but he cherishes his academic experience in the United States.

In comparison with Nigeria, students in Ojos school in the US are given a voice at every-decision making process and even review their professors. This review determines the promotion or retention of the lecturer.

Here in the US, students are given a genuine voice at every decision-making step, like identifying the direction of your research, the employment of new professors, and sometimes have a say in course design through regular class feedbacks

You are allowed to review your class and professor at the end of the semester which counts towards promotion or retention of the professor. As such, everyone takes the job seriously and they realise that they are employed because of the students, he boasted.

Looking back at his experience while in Nigeria, Ojo believes the academic template in Nigerian institutions is a sharp contrast with that of the United States.

I feel like its the other way round in my personal and acquired experience in some Nigerian universities where some professors are not easily approachable and students feel helpless in cases of misconduct.

There are also structures in place in US universities to improve the physical and mental health of students to better cope with academic stress.

Ojo believes the Nigerian education sector can be improved if lecturers, professors, teachers and members of staff adopt, embrace and believe that education is a service industry.

His advice is that structures be put in place to ensure that lecturers and others realises that the sole purpose of their employment is all about providing quality service to the students who mostly foot their salaries.

Education is a service industry and they are occupying those privileged positions mainly because of the availability of students to teach and not the other way round.

This can be achieved, in part, by developing a system for anonymous course reviews after each semester and making sure the reviews matter in some way.

He also believes that Nigeria needs to improve funding to universities especially for research and development, conferences, and periodic training of staff.

For example, the budget for Oklahoma State University for fiscal year 2019 was $1.3 billion, while that of Nigeria as a whole was about $1.72 billion (N620.5 billion).

However, we will only be kidding ourselves if we continually pump money into our universities and do nothing to get rid of loopholes that enhance systemic corruption with little consequences in our society.

His experience in white-dominated Oklahoma can be described as smooth sail. He described residents of his host community as the nicest people to be around both on and off-campus.

I have a very much collegial relationship with my classmates and professors.

Here, professors treat us as colleagues, with much dignity and respect. Their doors are always open for discussion and they will sometimes come over to your desk to discuss as well if they know you have developed expertise in an area.

He explains that this was a huge culture change for him in comparison with his home country Nigeria.

The way some of our professors in Nigeria relate with their students can sap all the confidence in your ability to relate with older professionals if you dont experience life elsewhere.

Ojo is a student who has worked his way to the top. Upon arrival in the US, he had to improve his hands-on laboratory experience from EKSU standard to the standards in the US due to the huge differences.

Among tackling other challenges, his doggedness and diligence earned him the Honorary Marshal award which is the highest honour awarded to a student during the graduation season.

He explains how he got the highest honour.

Each program in the university nominates one applicant for this award and the university selects only two candidates noted for their academic achievements, scholarly contributions, and service to the university and community.

I was deeply honored with this award which meant that I got to lead my esteemed colleagues in the procession at graduation, have reserved seats for my proud family, recognized at the ceremony among other perks, he explained.

Other awards Ojo received during his Ph.D. include the 2016 top five Minority Investigator award by the American Society of Nutrition, the 2017 most outstanding Ph.D. student award by the College of Human Sciences, and the 2018 excellence in mentoring undergraduates in research award also by the College of Human Sciences, in Oklahoma State University.

His next program centers around inflammatory bowel disease research with a team led by Michael Rosen at Cincinnati Childrens Hospital Medical Center, Ohio.

In addition, he hopes to continually use his Bestman Academy platform to enlighten good students all over the world on how to take advantage of graduate degree opportunities that exist all over the United States.

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From Ekiti to Oklahoma: How A Nigerian Conquered The Odds - Channels Television

If we continue to develop our technology without wisdom or prudence, our servant may prove to be our executioner

Psychiatric and neurodegenerative illnesses are becoming more and more prevalent as we march into the 2020s. We dont have to spend much time pondering as to why this phenomenon has come to the fore, when we consider the extreme mismatch between our ancient physiology and the western diet and lifestyle. Most readers will be familiar with some of the reasons for this dilemma: insufficient physical exercise, spending too much time in an artificial environment, emotional traumas, stress overload, a bad diet, nutrient deficiencies, smoking, excess alcohol consumption, and so on.

Poor biological functioning from addictions such as smoking, can (in the case of the latter), rapidly age our lungs, our arteries, our oxygen/CO2 exchange, our liver, and many other organs and processes, not to mention our antioxidant defences, thus rendering them a far higher biological age than their (our) chronological age. And sadly, the damage done to our arteries, alveoli, and so on, is normally irreparable. Naturally, this can have a very negative impact on our mental health. A recent large scale study on biological aging, which applied age-prediction models using blood biochemistry, cell counts, and AI, to 149,000 smokers, showed that: smokers exhibited [far] higher aging rates than non-smokers, regardless of their cholesterol ratios and fasting glucose levels. From my point of view, biomarker analysis is the future, as it is likely to provide a: quantitative assessment of the effect of environmental factors on [our] rate of biological aging, and hence, our mental well-being.

The WHO has now reclassified RF EMFs as a class 2B carcinogen, placing it in the same carcinogenic class as lead & the pesticide DDT

These electromagnetic fields (EMFs), which are invisible clouds of electricity emitted by radio frequency (RF), radio, Wi-Fi internet, and mobile phones, are a huge problem, and as research indicates, one that is about to get far more serious. Indeed, two-time Nobel nominee, Dr. Robert Becker, MD, the author of The Body Electric: Electromagnetism and the Foundation of Life, stated: I have no doubt in my mind that at the present time, the greatest polluting element in the earths environment is the proliferation of electromagnetic fields.

Switzerland replaced wireless internet in schools with wired internet. Germanys public health department recommends citizens switch off WiFi when not using it

Although electrical impulses generated by our biological processes travel through our bodys cells, muscles, nerves, and virtually every system and cell within us, and carry a charge; substantial research (over 2,000 peer-reviewed papers), has nonetheless, proved that artificial EMFs can be responsible for: memory and thinking difficulties; attention/concentration dysfunction; tiredness/fatigue; anxiety/restlessness; malaise; irritability, listlessness; dizziness; brain fog; tinnitus; depression; insomnia/sleep disturbance; and negative changes in EEG (which show electrical activity/brain wave patterns), and even our DNA.

Alzheimers & Dementia

And the news just keeps getting worse, there are in excess of: 70 studies linking EMFs to dementia. The research also includes several epidemiological studies and meta-analyses that link exposure to EMFs and Alzheimers onset. [Indeed], overnight exposure to EMFs significantly increases the secretion of a protein that is involved in the development of Alzheimers disease. [Further], EMF exposure also negatively affects the entorhinal cortex, the area of the brain that is first affected by Alzheimers disease. But, as taking a holistic perspective is not part of the agenda, will your doctor tell you this?

These days, it is crucial to think outside the box. So to that end, if you have WI-FI at home, turn it off when you go to bed, and simply put it back on when you get up. And when it comes to your mobile, dont keep it next to your body when you are not using it, and when you go to bed, if you need to keep it on, then ensure that you put it at least 12 feet away from you, and at best, in another room! The proof is in the pudding, so to speak, and if you do this, then you are very likely to feel a very positive mental and physical change.

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How WiFi, EMFs and Other Negative Factors Degrade Our Mental Health - E-counseling

Los Angeles, United State- The report presented here prepares market players to achieve consistent success while effectively dealing with unique challenges in the global Automated Biochemistry Analyzers market. The analysts and researchers authoring the report have taken into consideration multiple factors predicted to positively and negatively impact the global Automated Biochemistry Analyzers market. The report includes SWOT and PESTLE analyses to provide a deeper understanding of the global Automated Biochemistry Analyzers market. All of the leading companies included in the report are profiled based on gross margin, market share, future plans, recent developments, target customer demographics, products and applications, and other critical factors. The report also offers regional analysis of the Automated Biochemistry Analyzers market with high focus on market growth, growth rate, and growth potential.

Major Key Manufacturers of Automated Biochemistry Analyzers Market are: Abbott, Danaher, Hitachi, Roche, Siemens, Thermo Fisher Scientific,

Download PDF Sample Copy of Automated Biochemistry Analyzers Market Report: https://www.qyresearch.com/sample-form/form/979074/global-automated-biochemistry-analyzers-industry-trends-and-forecast-to

Global Automated Biochemistry Analyzers Market by Type Segments:

Stationary Biochemistry Analyzers, Portable Biochemistry Analyzers,

Global Automated Biochemistry Analyzers Market by Application Segments:

Hospital and Diagnostic Laboratories, Home Care, and Academic, Research Institutes,

Regional Growth: The report offers in-depth analysis of key regional and country-level Automated Biochemistry Analyzers markets, taking into account their market size, CAGR, market potential, future developments, and other significant parameters. It includes geographical analysis of both developed and emerging markets for Automated Biochemistry Analyzers. This helps readers to understand the growth pattern of the Automated Biochemistry Analyzers market in different regions and countries. In addition, the regional analysis will provide market players an extremely important resource to plan targeted strategies to expand into key regional markets or tap into unexplored ones.

The report provides a 6-year forecast (2019-2025) assessed based on how the Automated Biochemistry Analyzers market is predicted to grow in major regions like USA, Europe, Japan, China, India, Southeast Asia, South America, South Africa, Others.

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Take a look at some of the important sections of the report

Market Overview: Readers are informed about the scope of the global IAutomated Biochemistry Analyzers market and different products offered therein. The section also gives a glimpse of all of the segments studied in the report with their consumption and production growth rate comparisons. In addition, it provides statistics related to market size, revenue, and production.

Production Market Share by Region: Apart from the production share of regional markets analyzed in the report, readers are informed about their gross margin, price, revenue, and production growth rate here.

Company Profiles and Key Figures: In this section, the authors of the report include the company profiling of leading players operating in the global Automated Biochemistry Analyzers market. There are various factors considered for assessing the players studied in the report: markets served, production sites, price, gross margin, revenue, production, product application, product specification, and product introduction.

Manufacturing Cost Analysis: Here, readers are provided with detailed manufacturing process analysis, industrial chain analysis, manufacturing cost structure analysis, and raw materials analysis. Under raw materials analysis, the report includes details about key suppliers of raw materials, price trend of raw materials, and important raw materials.

Market Dynamics: The analysts explore critical influence factors, market drivers, challenges, risk factors, opportunities, and market trends in this section.

We follow industry-best practices and primary and secondary research methodologies to prepare our market research publications. Our analysts take references from company websites, government documents, press releases, and financial reports and conduct face-to-face or telephonic interviews with industry experts for collecting information and data. There is one complete section of the report dedicated for authors list, data sources, methodology/research approach, and publishers disclaimer. Then there is another section that includes research findings and conclusion.

About Us:

QYResearch always pursuits high product quality with the belief that quality is the soul of business. Through years of effort and supports from the huge number of customer supports, QYResearch consulting group has accumulated creative design methods on many high-quality markets investigation and research team with rich experience. Today, QYResearch has become a brand of quality assurance in the consulting industry.

This post was originally published on The Picayune Current

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Automated Biochemistry Analyzers to Boost the Revenue over the Forecast Period (2019-2025) | Abbott, Danaher, Hitachi, Roche, Siemens - The Picayune...

GlobalBiochemistry Analyzers Market: Overview

The report details an exhaustive account of the global biochemistry analyzers market along with numerous associated factors. Some of these factors that are included in the report are drivers, restraints, competitive analysis, latest trends and opportunities, geographical outlook, and many other aspects. The study covered in the report spans a forecast period from 2018 to 2028. From an overall perspective, the report is expected to exist as a valuable insight to businesses which are already operating in the global biochemistry analyzers market, as well for those who intend to newly establish themselves in this environment.

GlobalBiochemistry Analyzers Market: Market Potential and Restraints

Widespread advancements in the medical field have primarily been responsible for driving the global biochemistry analyzers market. Moreover, with rising geriatric population, the numbers of health issues are gradually increasing, thereby increasing demand for relevant treatments that involve biochemical analyzers. In addition, these analyzers possess a high rate of identification of a specific pathogen, consequently providing high clarity and accuracy. These characteristics make the use of the biochemical analyzers more suitable than other alternatives, thereby boosting growth in the global biochemical analyzers market.

To Know the Scope of Our Report Get a Brochure on Biochemistry Analyzers Market here @https://www.transparencymarketresearch.com/sample/sample.php?flag=B&rep_id=50526

Technological advancements are expected to increase even more in the near future, consequently projected to further stoke expansion in the global biochemical analyzer market. Increasing use of the analyzers in drug monitoring, drug abuse detection, and drug provision, owing to rise in the number of health conditions too is notably contributing towards growth witnessed by the global biochemistry analyzers market.

However, this market is hindered owing to several factors. A prominent obstacle present in its growth involves lack of expertise and shortage of necessary manpower required to provide the treatments that involves use of biochemistry analyzers in remote and underdeveloped regions. Owing to this, the market remains restrained geographically. Moreover, high costs of manufacturing the analyzer compounds might cause difficulties for small-scale healthcare centers to afford the required equipment.

In addition, there are several complexities involved with carrying out medical processes that make use of the analyzers. Due to this, people might prefer traditional and cheaper alternatives, which is notably hampering progress in the global biochemistry analyzers market. Nonetheless, key players are soon expected to introduce cost-effective analyzer production procedures, thus blanketing most restraints affecting the global biochemistry analyzers market.

GlobalBiochemistry Analyzers Market: Geographical Outlook

This market is mainly spread across North America, Europe, Asia Pacific, the Middle East and Africa, and Latin America. Of these, a strong medical infrastructure in North America has made this region hold a leading stance with maximum market share. Many organizations are growing in the global biochemistry analyzers market in North America owing to the availability of necessary funds, mainly to conduct research and develop new and efficient treatments.

However, apart from North America, Asia Pacific too showcases a splendid growth present in the global biochemistry analyzers market. This is majorly due to the introduction and utilization of various treatment procedures wherein biochemistry analyzers play a huge role. In addition, several companies are pouring extensive investments in developed economies located in Asia Pacific, which is anticipated to strengthen the market in this region.

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GlobalBiochemistry Analyzers Market: Competitive Landscape

This market depicts the presence of a substantially competitive vendor landscape, with the presence of a handful of players exerting their respective dominance. Regulation of treatment costs, achieving geographical expansion, and bringing forth medical treatment efficiency are key strategies implemented by most players operating in the global biochemistry analyzers market. Abbott Diagnostics Inc., Hologic, Inc., Transasia Biomedicals Ltd., Beckman Coulter Inc., Roche Diagnostics GmbH, Siemens AG, Randox Laboratories Ltd., Awareness Technology, Inc., Shenzhen Mindray Bio-Medical Electronics Co., Ltd., and Nova Biomedical Corp., are chief players operating in this sector.

I am an active day trader spending the majority of my time analyzing earnings reports and watching commodities and derivatives. I have a Masters Degree in Economics from Westminster University with previous roles counting Investment Banking.

Address: 4109 Briarwood Road Crane, MO 65633, USAPhone: (+1) 417-892-8092Email: Sheilashipman@newscastreport.com

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Biochemistry Analyzers Analysis and Forecast up to 2026 - News Cast Report

COLUMBUS, Ohio-- Christopher Lewis is an example of why you shouldn't let anyone tell you it's not possible.

What the OSU Senior had to overcome in his life would make anyone want to quit.

But Lewis has never met an obstacle he couldn't overcome.

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Shortly after his birth, he was diagnosed with cerebral palsy.

The disease left his make it difficult to use the right side of his body.

But that didn't stop Lewis. He learned to play the piano and later took up the trombone.

While in High School he got the crazy idea of trying out for one of the best college marching bands in the entire country.

He started telling himself, "Never tell yourself you're not good enough," he said.

But he wondered if he would ever be good enough to play among the Ohio State Marching Band also known as" The Best Damn Band In the Land"

"At one point I really felt like stepping away I just didn't feel like I was going to be good enough," he said.

Because of his disability, Lewis had a difficult time adapting to the grueling marching style. His right arm would wear out holding his trombone and he could not point his toe enough to match the rest of the students.

The band marches on its tip-toes.

He would work with an Ohio State University doctor who used a muscle stimulator under the ball of his foot to help him lift his toe when he raised his leg. It worked.

There are just 228 slots for members of the OSU Marching Band. But a mere 28 positions for trombone players.Lewis was a long shot.

On his final tryout, in his senior year, he finally heard his name called.

He made it.

"It's been a dream come true," he said.

Lewis will graduate in May with a degree in Biochemistry.

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"It's a dream come true" OSU musician overcomes disability and earns spot in marching band - 10TV

University College Cork currently has 21 jobs on offer with some of them paying incredible money.

Unfortunately for some of these jobs you will need plenty of experience and expertise - hence the great pay.

But it's always interesting to look at what jobs our out there and what it would take to nab a job in the local University.

There are plenty of lecturing jobs available at the moment so this is worth looking at if that is your type of thing.

Here's a list of all the roles available with information on how to apply over at UCC's official website.

- Professor & Senior Lecturer in Applied Psychology, School of Applied Psychology

- Executive Director of Development and Alumni Relations

- IT Project Management Officer, IT Services

- Lectureship in Development Education & Global Citizenship

- Nurse, Student Health Department

- Post-Doctoral Researcher, APC Microbiome Ireland

- Post-Doctoral Researcher - 2 positions, School of Biochemistry and Cell Biology

- Post-Doctoral Researcher, Centre for Research in Vascular Biology/APC Microbiome Ireland

- Post-Doctoral Researcher, Cork University Business School, College of Business and Law

- Post-Doctoral Researcher, School of Nursing and Midwifery

- Professor in Economics & Professor in Economics, Cork University Business School, University College Cork

- Research Assistant, School of Nursing and Midwifery

- Research Officer (Policy & National Programmes)

- Research Support Officer - Clinical (Nurse/Physiotherapy), School of Nursing and Midwifery

- Research Support Officer - Administration, Centre for the Integration of Research, Teaching and Learning (CIRTL)

- Research Support Officer - Administration, Environmental Research Institute/School of Biological, Earth and Environmental Sciences

- Senior Lectureship in Paramedical Science, School of Medicine

- Senior Post-Doctoral Researcher, MaREI Centre, Environmental Research Institute

- Senior Post-Doctoral Researcher, School of Computer Science & IT

- Senior Research Co-Coordinator (Senior Clinical Neuropsychologist), INFANT Research Centre, College of Medicine & Health

- Spin-Out Manager, UCC Innovation

And best of luck if you do end up applying for any of the roles.

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UCC currently taking applicants for 21 jobs with some incredible pay - Cork Beo

Editorial by Kendall Henry

Often, the news shows our beloved City of South Fulton in a negative light. They dont show the positive events, the people produced, and the impacts made every day in South Fulton. The media does not show The South Fulton Effect. I was raised in the City of South Fulton. I now attend the University of Georgia as a Biochemistry and Molecular Biology major and Public Health minor. I am heavily involved on campus. I have made it my mission to apply my upbringing to my current life.

I attended Randolph ElementarySchool. As a dolphin, I was introduced to Girl Scouts. I started off as aBrownie in 2009 as part of the Randolph Girl Scouts and completed my GS journeyin May 2019 with earning the prestigious Gold Award. I devoted a part of my lifeto Girl Scouts and community service. In addition, I participated in WAPR.Welcome Asa Philip Randolph was the televised morning announcements. I was anews anchor on the show during my fourth and fifth grade year. This opportunityhelped me gain comfort in public speaking. My first cheerleading experience waswith Sandtown Park Recreational Sports. I cheered for the football team. Ilearned the basics of teamwork and cheerleading here. The South Fulton Effectis how I now organize my own service events, participate in multiple serviceorganizations on UGAs campus, speak in front of large crowds with no anxiety,and cheer on the UGA Competition Cheerleading Squad.

During my fifth-grade year, Iremember hearing that some of my classmates were planning to attend RidgeviewCharter for middle school. When I asked them why, they all told me because itis better than Sandtown. I was not quite sure what that meant but I knew Iwanted to go to the better school. My parents quickly shut down my notionsand I was off to Sandtown for middle school. As a Jaguar, I participated in toomany clubs to name. From yearbook club to cheerleading, I stayed after schoolevery day of the week for three years straight. Sandtown provided me with somany opportunities that broadened my horizons. I am forever grateful for that.This taught me time management and prioritizing. I know that Sandtown was thebetter school and gave me foundation. The South Fulton effect is how learnedhow to balance all of my organizations at UGA and still make stellar grades.

I then became a lion at WestlakeHigh School. This was the school to attend. My old classmates from Randolphattended North Fulton middle schools, fled back down to the south to gainadmissions into our esteemed Magnet program. At Westlake, I learned early aboutthe college admissions process. Therefore, from freshman year on forward I knewmy goals. During my sophomore year, UGA admissions office hosted an in-housefield trip. This was my first introduction to what the University of Georgiahad to offer, and I also met my admissions counselor. I had no idea that Iwould later attend this was the school for my undergraduate degree. Also, I wasin the Magnet and International Baccalaureate program. These programs pushed meto critically think and strive for academic excellence. Ultimately, I graduatedwith an IB Certificate and in the top 25 of my 500+ class. Sandtownsfoundation helped me stay involved at Westlake and I essentially touched everyclub the school had to offer. I cheered on Friday nights and led my school asSGA Vice President weekly. In addition, I developed the infamous renaming thecity petition as a Westlake Lion. The petition allowed me to see governmentprocedures and acquire a sense of community. Due to the Magnet/IB programrigor, I was a competitive college applicant and gained admissions into aprestigious public institution debt-free. In addition, I can handle heavycourse loads with no problem. This is how I completed eight courses andfinished my first college semester with a 3.9 GPA. Due to the vulnerability andsuccess of my petition, I am now the only African American female Senatorrepresenting the class of 2023 at UGA. In this role, I have the power to writelegislation that impacts the entire 35,000 student population. This is theSouth Fulton effect.

I am grateful for my upbringing in the City of South Fulton. My experiences here have truly shaped me and made me the person I am today. The people I have met here have been lifelong influences in my life. I will cherish this forever. Realize the positivity that is nurtured here. Power is being cultivated here. We must continue the South Fulton Effect.

About the Author

Kendall Henry is apermanent resident of the City of South Fulton. She is a recent graduate ofWestlake High School. She now attends college at The University of Georgiawhere she is majoring in Biochemistry and Molecular Biology.

Henry is most knownfor her participation in the city name change referendum. Henry spoke beforethe city council and delivered speeches on the importance of including theresidents in voting processes. As a result of her petition, the mayor of thecity vetoed the first vote made by the council and reverted the name back toThe City of South of Fulton. Kendall has been interviewed on WSB-TV, 11Alive,CBS46, and WABE 90.1.

Her biggest motivation for facilitating this movement was to show children and teens that you can still be involved in politics and be active in your community even though you are not eligible to vote. Henry is also a recipient of the Girl Scout Gold Award and Presidential Volunteer Service Award, both prestigious awards that are solely based on community service. Kendall has a passion for helping people to make progress in her community.

Photo: Kendall Henry addresses the City Council over the controversial name change in 2017.

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South Fulton Youth Editorial: The South Fulton Effect - City of South Fulton Observer

The Department of Sports and Health Tourism, Sports Physiology, and Medicine of the Faculty of Physical Education has had its anniversary celebration 10 years from its founding. The staff of the department made a good gift for the anniversary: they published three articles in Q1 journals in the areas of medicine, biochemistry, genetics, and molecular biology.

2019 was a very busy year for the department: the team carried out two projects with the support of the Russian Science Foundation. The first is devoted to the study of myokines special proteins that are produced by muscles during physical exercise (the project manager is Professor Leonid Kapilevich, head of the department). In the second project, the effect of physical exertion on the compensation of type 2 diabetes mellitus was studied (the project manager is Professor Alexander Chibalin, a staff member of TSU and Karolinska Institute, Sweden). This resulted in 15 scientific articles in journals included in the international databases Web of Science and Scopus, including three articles in journals from the first quartile.

The article Transcriptomic Changes Triggered by Ouabain in Rat Cerebellum Granule Cells: Role of 3- And 1-Na +, K + -ATPase-mediated Signaling was published in PLoS ONE (the USA journal, impact factor 6.26, 27th of 2,836 journals in the category Medicine Myology). In this work, the role of monovalent ions (sodium and potassium) as regulators of intracellular processes was studied.

This is a fundamentally new approach, explains Leonid Kapilevich. Traditionally, calcium is considered the main ion that is the regulator of cellular metabolism, especially in muscles. However, the team showed that it is the ratio of sodium and potassium in the cell that is able to regulate the process of gene transcription, moreover, regardless of calcium.

The article Elevation of Intracellular Na + Contributes to Expression of Early Response Genes Triggered by Endothelial Cell Shrinkage was published in the journal Cellular Physiology and Biochemistry (published in Sweden, impact factor 5.11, 51stof 2,124 journals in Biochemistry, Genetics and Molecular Biology ). This article continues the research whose results are described in the previous article. Here, an attempt is made to understand how sodium ions affect the metabolic processes in the cell. It was found that one of the most likely ways is by changing the osmotic pressure of the cytoplasm and, as a consequence, the volume of the cell and its components.

The article Low AS160 and High SGK Basal Phosphorylation Associates with Impaired Incretin Profile and Type 2 Diabetes in Adipose Tissue of Obese Patients was published in the journal Diabetes Research and Clinical Practice (published in the Netherlands, impact factor 3.26, 26th of 133 journals in Internal Medicine). The study examined molecular changes in adipose tissue in patients with diabetes, which contribute to impaired glucose metabolism and can serve as a target for the therapeutic effect of exercise.

The tenth anniversary against the background of the centennials of other departments and faculties looks, of course, modest, but even for this short period the department has something to be proud of, says Leonid Kapilevich. During this time, two doctoral and nine masters theses were defended at the department, 15 student manuals were published, 115 articles were published in journals included in international databases, five monographs, and two grants from the Russian Science Foundation were won.

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Scientists' articles have been published in top journals - Mirage News

A primary project for Garrett Gibbons, a postdoctoral researcher at the Center for Neurodegenerative Disease Research (CNDR), is to develop novel tau antibodies as possibletherapies to treat Alzheimers disease. When in the thick of it, the scientific process becomes a huge, timelyand sometimes redundanttask.

One particular experiment comes to mind: Gibbons and his colleagues were injecting tau into mice models, which the mice developed antibodies against, and when they were harvested, the cells were paired with another cell to make a hybridoma. The problem? After two times running the full experiment, the antibodies still didnt meet certain criteria to be applicable.

Gibbons, quite disheartened, told his adviserVirginia Man-Yee Lee, a Perelman School of Medicine professor and director of CNDR, that the benchmark was too high.

Virginia was like, Well, try again, Gibbons recalled. She pushed back and said how she thought we could do better.

Although admittedly frustrated at the time, Gibbons rethought the project, and, ultimately, underwent a revamped test a third time.

And we got better antibodies, performing better than the previous ones, he said. They are now the candidates that we are evaluating as immunotherapy in mice, as potential treatments for Alzheimers disease.

It is safe to say, noted Gibbons, that without this kind of persistence from Lee, Alzheimers research wouldnt be nearly as developed as it is today. A pioneer in the field of neurodegenerative diseases, Lee was recently recognized for her four decades of work with a $3 million Breakthrough Prize in Life Sciences, an award backed by major technology leaders from companies including Google and Facebook.

Growing up in Hong Kong in a very traditional Chinese family, my mother never wanted me to become a professional, let alone a scientist, Lee said to the crowd, while accepting her Breakthrough Prize at the Oscars of Science in Silicon Valley in early November. Thankfully John Trojanowski, my life partner and collaborator, convinced me to embark on this wonderful journey with him, identifying proteins that are involved in devastating neurological diseases, which affect more and more of us, but have no effective treatment.

Lee, with a background in biochemistry and neuroscience, and Trojanowski, who studied pathology and neuropathology, have toiled alongside each other at Penn since the mid-1980s. They began work in Alzheimers research when it was very uncommon to do soin fact, their mentors urged them to stay far, far away from it.

What [our mentors] saw as a swamp, said Trojanowski, we saw as a huge challenge and opportunity that has led to an engaging career.

Before Lee and Trojanowski, prior studies had determined that an Alzheimers patients brain progressively accumulates plaques, abnormal clusters of protein fragments called beta-amyloid, that build up between nerve cells, and tangles, which form inside dying cells. Using this as a starting point, the duo detected their first major finding in 1991: that tau is the building block protein of the neurofibrillary tangles.

In 1997, Lee and Trojanowski found that Lewy bodies, the hallmark brain pathology of Parkinsons disease, are formed by alpha-synuclein. Knowing what causes Lewy bodies is important to Alzheimers researchers because about 50 percent of Alzheimers patients have Lewy bodies that contribute to cognitive deficits.

Then, in 2006, they discovered the pathological protein deposits in amyotrophic lateral sclerosis, or ALS, and frontotemporal degeneration, or FTD, are formed by TDP-43, a multifunctional DNA- and RNA-binding protein, and these deposits are also present in a large number of Alzheimers patients brains.

Lee was specifically recognized for the Breakthrough Prize for discovering TDP-43 protein aggregates in FTD and ALS, and revealing that different forms of alpha-synuclein, in different cell types, underlie Parkinsons disease and Multiple System Atrophy.

This is exceptionally important work, and we are very proud that it is taking place at Penn. Penn President Amy Gutmann

The discoveries led by Dr. Lee and her team are extraordinary, and absolutely worthy of the prestigious Breakthrough Prize, said Penn President Amy Gutmann, who went to Silicon Valley to support Lee in receiving her honor. Dr. Lee and her team have worked to fully understand the different segments of Alzheimers disease and other related disorders, using that knowledge to develop models that are becoming the foundation for therapies that will, hopefully, stop or reverse these diseases. This is exceptionally important work, and we are very proud that it is taking place at Penn.

Its rewarding, Lee said, to reflect on how researchers are becoming increasingly interested in TDP-43s involvement in neurodegenerative diseases, and the biology that is able to follow, now.

It is gratifying that people can, and people are very interested in, using the system that weve built to identify potential therapies, Lee explained. I am really optimistic that maybe some treatment for Alzheimers and Parkinsons will become available in the next, lets say, one or two decades.

Gibbons, who can distinctly remember being a teenager and watching his grandfather cope with all the stages of Alzheimers, as well as the impact it had on his family, knew rather early it would be a field he would want to pursue. But, it wasnt until he was immersed in the research that he realized how complicated it really was.

When I first got to Penn, I was kind of blown away with the challenge and sort of became cynical and pessimistic, Gibbons said. But I like the way that Dr. Lee continues to forge ahead and isnt overwhelmed as a young investigator, that gives me a lot of inspiration and hope. Of course there will be failures, and of course science is hard. This is worthwhile, and we will get there.

In terms of Lee as a leader, Mike Henderson, a research associate in her lab, said he appreciates the way she guides him in his learning, but also provides him with the independence needed to encourage innovative, out-of-the box thinking.

She really shows you what it takes to be a good scientist in the field, he said, adding how inquisitive Lee always is. Shes very curious and I think thats really what has driven her lab and what has made her so successful.

The main reason Henderson came to Penn, he noted, was to work not only with Lee and Trojanowski, but also with the team theyve assembled through the creation of the CNDR, which celebrated its 25th year in 2018. About 50 people are part of the center today.

From the Maloney Building on Penns campus, where CNDR is housed, Lee and Trojanowski have been able to foster multidisciplinary collaborations between basic and clinical scientists, and provide resources to enable the very best research projects, including a brain and biosample bank, a drug discovery program, data management and biostastic support, and expertise in biochemistry, histology, molecular biology, microscopy, tissue culture, and genetics.

John and I spent a lot of time developing an infrastructure to do this type of work, and Penn has been such a fantastic environment, said Lee, who acknowledged all of her collaboratorsstudents, postdocs, and staff scientistsat the Breakthrough event. I truly want to thank them for their dedication and commitment, she said.

Talking later, Trojanowski added, They have made possible all that we have accomplished.

There is no doubt about it: Talking about his beloved wife of 40-plus years is probably one of Trojanowskis favorite things to do. Shes always pushing herself to be better, and shes always pushing me to be better. She is driven, hardworking, very bright, determinedall of the things that you expect to see and need to see in people that are going to be as successful as she is.

Not only is she passionate about science, he adds, shes determined to solve any problem she ever sets her eyes on. Plus, shes an amazing preceptor, trainer, encourager of science in young people. She is just exceptional, he added.

Trojanowski attended the Breakthrough event with his wife, thrilled to stand by her side on such an exciting day. Its an outstanding recognition, he said.

One might think a $3 million check in the bank could be a ticket out of work, but for Lee, she was back in Philadelphia after just a couple days. As always, she rode her bike to the officeready and willing to take on her next challenge.

What Id like to do in the next 10 to 20 years, Lee said, is really work with companiespharmaceutical companies and biotechnology companiesto come up with treatments.

Virginia Man-Yee Lee is the John H. Ware 3rd Endowed Professor in Alzheimers Research in the Department of Pathology and Laboratory Medicinein the Perelman School of Medicine.

John Q. Trojanowski is the William Maul Measey - Truman G. Schnabel, Jr., M.D. Professor of Geriatric Medicine and Gerontology in the Department of Pathology and Laboratory Medicinein the Perelman School of Medicine.

The Breakthrough Prize in Life Sciences, founded in 2013, honors transformative advances toward understanding living systems and extending human life. It is sponsored by Sergey Brin, Priscilla Chan and Mark Zuckerberg, Pony Ma, Yuri and Julia Milner, and Anne Wojcicki.

Homepage photo: Today, about 50 people make up the Center for Neurodegenerative Disease Research, led by Lee and Trojanowski, who both expressed how thankful they are for such a great team.

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An Alzheimer's research pioneer, right here at Penn - Penn: Office of University Communications

Two Bates College scientists have received nearly $373,000 from the National Institutes of Health for first-of-its-kind research into the genetic functioning of bacteria that cause Lyme disease.

The project draws on new capabilities in high-resolution microscopy that make it possible to observe spatial arrangements of RNA in Borrelia burgdorferi, one of four Borrelia species that cause Lyme disease. This study of variations in RNA location and shape could eventually suggest new medical responses to Lyme, which strikes up to 300,000 people in the U.S. annually.

Receiving the $372,639 grant for the two-year project are physicist Travis Gould, an expert in the field of fluorescence nanoscopy, and biochemist Paula Schlax, who researches gene expression in spiral-shaped bacteria, also known as spirochetes, such as Lyme bacteria.

Biochemist Paula Schlax and physicist Travis Gould pose with Goulds STED super-resolution microscope in Carnegie Science Hall. (Phyllis Graber Jensen/Bates College)

RNA is an intermediate in the process of cells making proteins, says Schlax, a professor of chemistry and biochemistry at Bates. Were trying to understand generally how production of proteins gets turned on and off when the bacteria move from ticks to mammals and from mammals back to ticks changes in the bacterias environment that change the shape and location of RNA.

We know from other bacteria that RNAs location inside the cell seems to affect how long that RNA lasts whether its near the edges of the cell, or the ends of the cell, or spread out evenly inside. Our hypothesis is that how fast RNA gets broken down, or doesnt get broken down, probably helps the cell decide which proteins to make when conditions change, such as when the bacteria moves from the tick to a mammal or vice versa.

Variations in protein production could cause variations in the bacterias disease-causing capability. The more we understand that process, Schlax says, the easier it is to think about new targets for drugs and new therapeutics.

Until quite recently, the physical limitations of microscope technology curtailed its usefulness in testing such a hypothesis. The bacteria have a characteristic shape, says Gould: very skinny in relation to length. The length is typically around 20 microns, or millionths of a meter, but the bacterias internal diameter is vastly smaller, at about 200 nanometers, or billionths of a meter. (A piece of paper is about 100,000 nanometers thick.)

That 200 nanometers is, in the best-case scenario, at the limit of a conventional microscopes resolution, Gould says. So a conventional microscope cant answer these questions about where RNA is within that 200-nanometer cylinder.

But Gould, an associate professor of physics, is an innovator in imaging technologies that use lasers, fluorescing molecules, and other means to attain much higher resolution. For the NIH-funded research, he has adapted an existing Bates microscope that he built and that uses a process called stimulated emission depletion, or STED, to capture images of the B. burgdorferi RNA.

Going from older microscopy technologies to Goulds newly updated STED is like putting on glasses for the first time.

Specifically, he added another laser to the instrument that expands its imaging capability from two to three dimensions. Going from older technologies to this latest iteration, says Schlax, is like putting on glasses for the first time.

Complementary to the STED technology, the researchers and their students will use a technique called fluorescence in situ hybridization (FISH) that deploys fluorescent probes to specific parts of the transcripts that the microbes DNA imparts to its RNA.

The research will be the first to identify patterns of transcript localization within B. burgdorferi, and, notably, the first research to use STED microscopy for this sort of localization within any spirochete.

This is significant given the range and impact of diseases caused by such bacteria, including syphilis, yaws, periodontal disease, and leptospirosis, whose effects include kidney failure.

Joining Schlax and Gould in the project are Bates students and research associate Anna Bowsher, whose position is funded by the NIH grant. The work entails growing B. burgdorferi microbes in the lab, affixing individual cells to slides, and introducing DNA molecules, complete with fluorescent tags, that are tailored to activate a specific RNA response.

Then the slides will be examined with Goulds STED microscope, and the results compiled into a spatial-distribution analysis of different types of RNAs. The team hopes that they will have results to report by summer 2020.

The project will involve both thesis students advised by Gould and Schlax and students doing summer research. These kinds of projects really are great for students to see how science is done, says Schlax, and hopefully get their names on some papers and keep them interested in science.

With the use of fluorescing molecules now standard practice in high-resolution microscopy, STED imaging achieves enhanced resolution through a technique of selectively switching off such molecules. STED is one of a number of so-called super-resolution techniques developed to bypass the diffraction limit, a limit on the resolution of conventional microscopy imposed by the length of light waves.

Gould estimates that all told, there are likely two dozen or so labs equipped with commercially available STED microscopes, and another handful that use custom-built instruments like his.

Excerpt from:
Bates biochemist and physicist receive $373,000 for Lyme research - Bates News