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Recent Articles | Physiology | The Scientist Magazine

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Running releases an enzyme that is associated with memory function in mice and humans.

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By Chris Tachibana | February 1, 2016

Is the public dissection of zoo animals a boon to research and education, a PR nightmare, or both?

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By The Scientist Staff | February 1, 2016

Watch footage from the public dissection of Marius, the young giraffe at the Copenhagen Zoo who was ultimately fed to predators at the facility. (CAUTION: GRAPHIC IMAGES)

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By Bob Grant | January 25, 2016

Researchers confirm the unprecedented endothermic abilities of a South American reptile.

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By Kerry Grens | November 16, 2015

In mice lacking intestinal microbiota, white fat turns brown and obesity is prevented.

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By Kerry Grens | November 5, 2015

Scientists describe molecular underpinnings of salmon size and of fishes ability to navigate murky environments in separate studies.

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By Tracy Vence | November 1, 2015

The accumulation of fat within skeletal muscle, as happens with obesity, diminishes muscle performance.

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The latest analysis on GDF11, a proposed antiaging protein, blames discrepancies in the literature on misreported doses and misinterpretation.

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Researchers derive trophoblast stem cells from mouse fibroblasts, paving the way for cell therapy for placental dysfunction diseases.

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By Kerry Grens | October 8, 2015

Scientists know how to turn on these fat-combusting cells. Can these energy burners be used to combat obesity?

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Recent Articles | Physiology | The Scientist Magazine

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Graduate Program in Neuroscience

The study of neuroscience is one of the most exciting and challenging areas of human endeavor.

Yeatman Lab

The goal of the Graduate Program in Neuroscience is to produce the best neuroscientists possible. The breadth of our faculty allows us to provide interdisciplinary training drawing from a variety of topics, techniques and perspectives, including neuroanatomy, biochemistry, molecular biology, physiology, biophysics, pharmacology, in vivo brain imaging (e.g., fMRI, M-EEG), computational modeling and behavior. Agraduate of our program will be well versed in the neurosciences, prepared to conduct independent research, and equipped to pursue a variety of career paths.

Palmiter Lab

140+ faculty members of the University of Washington provide outstanding graduate training in all areas of modern neuroscience. Our students perform cutting-edge research, at a leading research university, in one of the most famously livable American cities.

What does it mean that we are a Program and not a department? It means that we draw faculty from departments across campus and from affiliated institutes across Seattle to train our students. Students in our program are often considered to be de facto members of the department in which their faculty mentors have a primary appointment, but their diplomas show that their PhD degree is in Neuroscience. Our faculty and students are bound together by a common commitment to graduate education in Neuroscience, and we all benefit from the synergy of our diverse approaches to understanding the brain.

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Graduate Program in Neuroscience

Home | neuroscience | Virginia Tech

The Neuroscience program at Virginia Tech takes a very broad view of Neuroscience considering any interactions that are directed or perceived by the nervous system as Neuroscience. For example, any expression of artistry is generated and perceived by brain circuits, as are emotions, motivation, empathy, passion and compassion. Communications between cells, individual organisms, organismal groups and even societies are governed by brain activity.

Whether a student wishes to pursue Neuroscience research in the future or simply acquire this wealth of knowledge, understanding Neuroscience makes us more competent human beings, and provides us skills to be applied to a multitude of careers in art, music, architecture, urban and community planning, law, finance, policy, politics, health care and many other professions.

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Anatomy – Wikipedia

Anatomy is the branch of biology concerned with the study of the structure of organisms and their parts.[1] Anatomy is inherently tied to embryology, comparative anatomy, evolutionary biology, and phylogeny,[2] as these are the processes by which anatomy is generated over immediate (embryology) and long (evolution) timescales. Human anatomy is one of the basic essential sciences of medicine.[3]

The discipline of anatomy is divided into macroscopic and microscopic anatomy. Macroscopic anatomy, or gross anatomy, is the examination of an animal's body parts using unaided eyesight. Gross anatomy also includes the branch of superficial anatomy. Microscopic anatomy involves the use of optical instruments in the study of the tissues of various structures, known as histology, and also in the study of cells.

The history of anatomy is characterized by a progressive understanding of the functions of the organs and structures of the human body. Methods have also improved dramatically, advancing from the examination of animals by dissection of carcasses and cadavers (corpses) to 20th century medical imaging techniques including X-ray, ultrasound, and magnetic resonance imaging.

Anatomy and physiology, which study (respectively) the structure and function of organisms and their parts, make a natural pair of related disciplines, and they are often studied together.

Derived from the Greek anatemn "I cut up, cut open" from ana "up", and temn "I cut",[4] anatomy is the scientific study of the structure of organisms including their systems, organs and tissues. It includes the appearance and position of the various parts, the materials from which they are composed, their locations and their relationships with other parts. Anatomy is quite distinct from physiology and biochemistry, which deal respectively with the functions of those parts and the chemical processes involved. For example, an anatomist is concerned with the shape, size, position, structure, blood supply and innervation of an organ such as the liver; while a physiologist is interested in the production of bile, the role of the liver in nutrition and the regulation of bodily functions.[5]

The discipline of anatomy can be subdivided into a number of branches including gross or macroscopic anatomy and microscopic anatomy.[6]Gross anatomy is the study of structures large enough to be seen with the naked eye, and also includes superficial anatomy or surface anatomy, the study by sight of the external body features. Microscopic anatomy is the study of structures on a microscopic scale, including histology (the study of tissues), and embryology (the study of an organism in its immature condition).[2]

Anatomy can be studied using both invasive and non-invasive methods with the goal of obtaining information about the structure and organization of organs and systems.[2] Methods used include dissection, in which a body is opened and its organs studied, and endoscopy, in which a video camera-equipped instrument is inserted through a small incision in the body wall and used to explore the internal organs and other structures. Angiography using X-rays or magnetic resonance angiography are methods to visualize blood vessels.[7][8][9][10]

The term "anatomy" is commonly taken to refer to human anatomy. However, substantially the same structures and tissues are found throughout the rest of the animal kingdom and the term also includes the anatomy of other animals. The term zootomy is also sometimes used to specifically refer to animals. The structure and tissues of plants are of a dissimilar nature and they are studied in plant anatomy.[5]

The kingdom Animalia or metazoa, contains multicellular organisms that are heterotrophic and motile (although some have secondarily adopted a sessile lifestyle). Most animals have bodies differentiated into separate tissues and these animals are also known as eumetazoans. They have an internal digestive chamber, with one or two openings; the gametes are produced in multicellular sex organs, and the zygotes include a blastula stage in their embryonic development. Metazoans do not include the sponges, which have undifferentiated cells.[11]

Unlike plant cells, animal cells have neither a cell wall nor chloroplasts. Vacuoles, when present, are more in number and much smaller than those in the plant cell. The body tissues are composed of numerous types of cell, including those found in muscles, nerves and skin. Each typically has a cell membrane formed of phospholipids, cytoplasm and a nucleus. All of the different cells of an animal are derived from the embryonic germ layers. Those simpler invertebrates which are formed from two germ layers of ectoderm and endoderm are called diploblastic and the more developed animals whose structures and organs are formed from three germ layers are called triploblastic.[12] All of a triploblastic animal's tissues and organs are derived from the three germ layers of the embryo, the ectoderm, mesoderm and endoderm.

Animal tissues can be grouped into four basic types: connective, epithelial, muscle and nervous tissue.

Connective tissues are fibrous and made up of cells scattered among inorganic material called the extracellular matrix. Connective tissue gives shape to organs and holds them in place. The main types are loose connective tissue, adipose tissue, fibrous connective tissue, cartilage and bone. The extracellular matrix contains proteins, the chief and most abundant of which is collagen. Collagen plays a major part in organizing and maintaining tissues. The matrix can be modified to form a skeleton to support or protect the body. An exoskeleton is a thickened, rigid cuticle which is stiffened by mineralization, as in crustaceans or by the cross-linking of its proteins as in insects. An endoskeleton is internal and present in all developed animals, as well as in many of those less developed.[12]

Epithelial tissue is composed of closely packed cells, bound to each other by cell adhesion molecules, with little intercellular space. Epithelial cells can be squamous (flat), cuboidal or columnar and rest on a basal lamina, the upper layer of the basement membrane,[13] the lower layer is the reticular lamina lying next to the connective tissue in the extracellular matrix secreted by the epithelial cells.[14] There are many different types of epithelium, modified to suit a particular function. In the respiratory tract there is a type of ciliated epithelial lining; in the small intestine there are microvilli on the epithelial lining and in the large intestine there are intestinal villi. Skin consists of an outer layer of keratinized stratified squamous epithelium that covers the exterior of the vertebrate body. Keratinocytes make up to 95% of the cells in the skin.[15] The epithelial cells on the external surface of the body typically secrete an extracellular matrix in the form of a cuticle. In simple animals this may just be a coat of glycoproteins.[12] In more advanced animals, many glands are formed of epithelial cells.[16]

Muscle cells (myocytes) form the active contractile tissue of the body. Muscle tissue functions to produce force and cause motion, either locomotion or movement within internal organs. Muscle is formed of contractile filaments and is separated into three main types; smooth muscle, skeletal muscle and cardiac muscle. Smooth muscle has no striations when examined microscopically. It contracts slowly but maintains contractibility over a wide range of stretch lengths. It is found in such organs as sea anemone tentacles and the body wall of sea cucumbers. Skeletal muscle contracts rapidly but has a limited range of extension. It is found in the movement of appendages and jaws. Obliquely striated muscle is intermediate between the other two. The filaments are staggered and this is the type of muscle found in earthworms that can extend slowly or make rapid contractions.[17] In higher animals striated muscles occur in bundles attached to bone to provide movement and are often arranged in antagonistic sets. Smooth muscle is found in the walls of the uterus, bladder, intestines, stomach, oesophagus, respiratory airways, and blood vessels. Cardiac muscle is found only in the heart, allowing it to contract and pump blood round the body.

Nervous tissue is composed of many nerve cells known as neurons which transmit information. In some slow-moving radially symmetrical marine animals such as ctenophores and cnidarians (including sea anemones and jellyfish), the nerves form a nerve net, but in most animals they are organized longitudinally into bundles. In simple animals, receptor neurons in the body wall cause a local reaction to a stimulus. In more complex animals, specialized receptor cells such as chemoreceptors and photoreceptors are found in groups and send messages along neural networks to other parts of the organism. Neurons can be connected together in ganglia.[18] In higher animals, specialized receptors are the basis of sense organs and there is a central nervous system (brain and spinal cord) and a peripheral nervous system. The latter consists of sensory nerves that transmit information from sense organs and motor nerves that influence target organs.[19][20] The peripheral nervous system is divided into the somatic nervous system which conveys sensation and controls voluntary muscle, and the autonomic nervous system which involuntarily controls smooth muscle, certain glands and internal organs, including the stomach.[21]

All vertebrates have a similar basic body plan and at some point in their lives, (mostly in the embryonic stage), share the major chordate characteristics; a stiffening rod, the notochord; a dorsal hollow tube of nervous material, the neural tube; pharyngeal arches; and a tail posterior to the anus. The spinal cord is protected by the vertebral column and is above the notochord and the gastrointestinal tract is below it.[22] Nervous tissue is derived from the ectoderm, connective tissues are derived from mesoderm, and gut is derived from the endoderm. At the posterior end is a tail which continues the spinal cord and vertebrae but not the gut. The mouth is found at the anterior end of the animal, and the anus at the base of the tail.[23] The defining characteristic of a vertebrate is the vertebral column, formed in the development of the segmented series of vertebrae. In most vertebrates the notochord becomes the nucleus pulposus of the intervertebral discs. However, a few vertebrates, such as the sturgeon and the coelacanth retain the notochord into adulthood.[24]Jawed vertebrates are typified by paired appendages, fins or legs, which may be secondarily lost. The limbs of vertebrates are considered to be homologous because the same underlying skeletal structure was inherited from their last common ancestor. This is one of the arguments put forward by Charles Darwin to support his theory of evolution.[25]

The body of a fish is divided into a head, trunk and tail, although the divisions between the three are not always externally visible. The skeleton, which forms the support structure inside the fish, is either made of cartilage, in cartilaginous fish, or bone in bony fish. The main skeletal element is the vertebral column, composed of articulating vertebrae which are lightweight yet strong. The ribs attach to the spine and there are no limbs or limb girdles. The main external features of the fish, the fins, are composed of either bony or soft spines called rays, which with the exception of the caudal fins, have no direct connection with the spine. They are supported by the muscles which compose the main part of the trunk.[26] The heart has two chambers and pumps the blood through the respiratory surfaces of the gills and on round the body in a single circulatory loop.[27] The eyes are adapted for seeing underwater and have only local vision. There is an inner ear but no external or middle ear. Low frequency vibrations are detected by the lateral line system of sense organs that run along the length of the sides of fish, and these respond to nearby movements and to changes in water pressure.[26]

Sharks and rays are basal fish with numerous primitive anatomical features similar to those of ancient fish, including skeletons composed of cartilage. Their bodies tend to be dorso-ventrally flattened, they usually have five pairs of gill slits and a large mouth set on the underside of the head. The dermis is covered with separate dermal placoid scales. They have a cloaca into which the urinary and genital passages open, but not a swim bladder. Cartilaginous fish produce a small number of large, yolky eggs. Some species are ovoviviparous and the young develop internally but others are oviparous and the larvae develop externally in egg cases.[28]

The bony fish lineage shows more derived anatomical traits, often with major evolutionary changes from the features of ancient fish. They have a bony skeleton, are generally laterally flattened, have five pairs of gills protected by an operculum, and a mouth at or near the tip of the snout. The dermis is covered with overlapping scales. Bony fish have a swim bladder which helps them maintain a constant depth in the water column, but not a cloaca. They mostly spawn a large number of small eggs with little yolk which they broadcast into the water column.[28]

Amphibians are a class of animals comprising frogs, salamanders and caecilians. They are tetrapods, but the caecilians and a few species of salamander have either no limbs or their limbs are much reduced in size. Their main bones are hollow and lightweight and are fully ossified and the vertebrae interlock with each other and have articular processes. Their ribs are usually short and may be fused to the vertebrae. Their skulls are mostly broad and short, and are often incompletely ossified. Their skin contains little keratin and lacks scales, but contains many mucous glands and in some species, poison glands. The hearts of amphibians have three chambers, two atria and one ventricle. They have a urinary bladder and nitrogenous waste products are excreted primarily as urea. Amphibians breathe by means of buccal pumping, a pump action in which air is first drawn into the buccopharyngeal region through the nostrils. These are then closed and the air is forced into the lungs by contraction of the throat.[29] They supplement this with gas exchange through the skin which needs to be kept moist.[30]

In frogs the pelvic girdle is robust and the hind legs are much longer and stronger than the forelimbs. The feet have four or five digits and the toes are often webbed for swimming or have suction pads for climbing. Frogs have large eyes and no tail. Salamanders resemble lizards in appearance; their short legs project sideways, the belly is close to or in contact with the ground and they have a long tail. Caecilians superficially resemble earthworms and are limbless. They burrow by means of zones of muscle contractions which move along the body and they swim by undulating their body from side to side.[31]

Reptiles are a class of animals comprising turtles, tuataras, lizards, snakes and crocodiles. They are tetrapods, but the snakes and a few species of lizard either have no limbs or their limbs are much reduced in size. Their bones are better ossified and their skeletons stronger than those of amphibians. The teeth are conical and mostly uniform in size. The surface cells of the epidermis are modified into horny scales which create a waterproof layer. Reptiles are unable to use their skin for respiration as do amphibians and have a more efficient respiratory system drawing air into their lungs by expanding their chest walls. The heart resembles that of the amphibian but there is a septum which more completely separates the oxygenated and deoxygenated bloodstreams. The reproductive system is designed for internal fertilization, with a copulatory organ present in most species. The eggs are surrounded by amniotic membranes which prevents them from drying out and are laid on land, or develop internally in some species. The bladder is small as nitrogenous waste is excreted as uric acid.[32]

Turtles are notable for their protective shells. They have an inflexible trunk encased in a horny carapace above and a plastron below. These are formed from bony plates embedded in the dermis which are overlain by horny ones and are partially fused with the ribs and spine. The neck is long and flexible and the head and the legs can be drawn back inside the shell. Turtles are vegetarians and the typical reptile teeth have been replaced by sharp, horny plates. In aquatic species, the front legs are modified into flippers.[33]

Tuataras superficially resemble lizards but the lineages diverged in the Triassic period. There is one living species, Sphenodon punctatus. The skull has two openings (fenestrae) on either side and the jaw is rigidly attached to the skull. There is one row of teeth in the lower jaw and this fits between the two rows in the upper jaw when the animal chews. The teeth are merely projections of bony material from the jaw and eventually wear down. The brain and heart are more primitive than those of other reptiles, and the lungs have a single chamber and lack bronchi. The tuatara has a well-developed parietal eye on its forehead.[33]

Lizards have skulls with only one fenestra on each side, the lower bar of bone below the second fenestra having been lost. This results in the jaws being less rigidly attached which allows the mouth to open wider. Lizards are mostly quadrupeds, with the trunk held off the ground by short, sideways-facing legs, but a few species have no limbs and resemble snakes. Lizards have moveable eyelids, eardrums are present and some species have a central parietal eye.[33]

Snakes are closely related to lizards, having branched off from a common ancestral lineage during the Cretaceous period, and they share many of the same features. The skeleton consists of a skull, a hyoid bone, spine and ribs though a few species retain a vestige of the pelvis and rear limbs in the form of pelvic spurs. The bar under the second fenestra has also been lost and the jaws have extreme flexibility allowing the snake to swallow its prey whole. Snakes lack moveable eyelids, the eyes being covered by transparent "spectacle" scales. They do not have eardrums but can detect ground vibrations through the bones of their skull. Their forked tongues are used as organs of taste and smell and some species have sensory pits on their heads enabling them to locate warm-blooded prey.[34]

Crocodilians are large, low-slung aquatic reptiles with long snouts and large numbers of teeth. The head and trunk are dorso-ventrally flattened and the tail is laterally compressed. It undulates from side to side to force the animal through the water when swimming. The tough keratinized scales provide body armour and some are fused to the skull. The nostrils, eyes and ears are elevated above the top of the flat head enabling them to remain above the surface of the water when the animal is floating. Valves seal the nostrils and ears when it is submerged. Unlike other reptiles, crocodilians have hearts with four chambers allowing complete separation of oxygenated and deoxygenated blood.[35]

Birds are tetrapods but though their hind limbs are used for walking or hopping, their front limbs are wings covered with feathers and adapted for flight. Birds are endothermic, have a high metabolic rate, a light skeletal system and powerful muscles. The long bones are thin, hollow and very light. Air sac extensions from the lungs occupy the centre of some bones. The sternum is wide and usually has a keel and the caudal vertebrae are fused. There are no teeth and the narrow jaws are adapted into a horn-covered beak. The eyes are relatively large, particularly in nocturnal species such as owls. They face forwards in predators and sideways in ducks.[36]

The feathers are outgrowths of the epidermis and are found in localized bands from where they fan out over the skin. Large flight feathers are found on the wings and tail, contour feathers cover the bird's surface and fine down occurs on young birds and under the contour feathers of water birds. The only cutaneous gland is the single uropygial gland near the base of the tail. This produces an oily secretion that waterproofs the feathers when the bird preens. There are scales on the legs, feet and claws on the tips of the toes.[36]

Mammals are a diverse class of animals, mostly terrestrial but some are aquatic and others have evolved flapping or gliding flight. They mostly have four limbs but some aquatic mammals have no limbs or limbs modified into fins and the forelimbs of bats are modified into wings. The legs of most mammals are situated below the trunk, which is held well clear of the ground. The bones of mammals are well ossified and their teeth, which are usually differentiated, are coated in a layer of prismatic enamel. The teeth are shed once (milk teeth) during the animal's lifetime or not at all, as is the case in cetaceans. Mammals have three bones in the middle ear and a cochlea in the inner ear. They are clothed in hair and their skin contains glands which secrete sweat. Some of these glands are specialized as mammary glands, producing milk to feed the young. Mammals breathe with lungs and have a muscular diaphragm separating the thorax from the abdomen which helps them draw air into the lungs. The mammalian heart has four chambers and oxygenated and deoxygenated blood are kept entirely separate. Nitrogenous waste is excreted primarily as urea.[37]

Mammals are amniotes, and most are viviparous, giving birth to live young. The exception to this are the egg-laying monotremes, the platypus and the echidnas of Australia. Most other mammals have a placenta through which the developing foetus obtains nourishment, but in marsupials, the foetal stage is very short and the immature young is born and finds its way to its mother's pouch where it latches on to a nipple and completes its development.[37]

Humans have the overall body plan of a mammal. Humans have a head, neck, trunk (which includes the thorax and abdomen), two arms and hands and two legs and feet.

Generally, students of certain biological sciences, paramedics, prosthetists and orthotists, physiotherapists, occupational therapists, nurses, and medical students learn gross anatomy and microscopic anatomy from anatomical models, skeletons, textbooks, diagrams, photographs, lectures and tutorials, and in addition, medical students generally also learn gross anatomy through practical experience of dissection and inspection of cadavers. The study of microscopic anatomy (or histology) can be aided by practical experience examining histological preparations (or slides) under a microscope. [39]

Human anatomy, physiology and biochemistry are complementary basic medical sciences, which are generally taught to medical students in their first year at medical school. Human anatomy can be taught regionally or systemically; that is, respectively, studying anatomy by bodily regions such as the head and chest, or studying by specific systems, such as the nervous or respiratory systems.[2] The major anatomy textbook, Gray's Anatomy, has been reorganized from a systems format to a regional format, in line with modern teaching methods.[40][41] A thorough working knowledge of anatomy is required by physicians, especially surgeons and doctors working in some diagnostic specialties, such as histopathology and radiology. [42]

Academic anatomists are usually employed by universities, medical schools or teaching hospitals. They are often involved in teaching anatomy, and research into certain systems, organs, tissues or cells.[42]

Invertebrates constitute a vast array of living organisms ranging from the simplest unicellular eukaryotes such as Paramecium to such complex multicellular animals as the octopus, lobster and dragonfly. They constitute about 95% of the animal species. By definition, none of these creatures has a backbone. The cells of single-cell protozoans have the same basic structure as those of multicellular animals but some parts are specialized into the equivalent of tissues and organs. Locomotion is often provided by cilia or flagella or may proceed via the advance of pseudopodia, food may be gathered by phagocytosis, energy needs may be supplied by photosynthesis and the cell may be supported by an endoskeleton or an exoskeleton. Some protozoans can form multicellular colonies.[43]

Metazoans are multicellular organism, different groups of cells of which have separate functions. The most basic types of metazoan tissues are epithelium and connective tissue, both of which are present in nearly all invertebrates. The outer surface of the epidermis is normally formed of epithelial cells and secretes an extracellular matrix which provides support to the organism. An endoskeleton derived from the mesoderm is present in echinoderms, sponges and some cephalopods. Exoskeletons are derived from the epidermis and is composed of chitin in arthropods (insects, spiders, ticks, shrimps, crabs, lobsters). Calcium carbonate constitutes the shells of molluscs, brachiopods and some tube-building polychaete worms and silica forms the exoskeleton of the microscopic diatoms and radiolaria.[44] Other invertebrates may have no rigid structures but the epidermis may secrete a variety of surface coatings such as the pinacoderm of sponges, the gelatinous cuticle of cnidarians (polyps, sea anemones, jellyfish) and the collagenous cuticle of annelids. The outer epithelial layer may include cells of several types including sensory cells, gland cells and stinging cells. There may also be protrusions such as microvilli, cilia, bristles, spines and tubercles.[45]

Marcello Malpighi, the father of microscopical anatomy, discovered that plants had tubules similar to those he saw in insects like the silk worm. He observed that when a ring-like portion of bark was removed on a trunk a swelling occurred in the tissues above the ring, and he unmistakably interpreted this as growth stimulated by food coming down from the leaves, and being captured above the ring.[46]

Arthropods comprise the largest phylum in the animal kingdom with over a million known invertebrate species.[47]

Insects possess segmented bodies supported by a hard-jointed outer covering, the exoskeleton, made mostly of chitin. The segments of the body are organized into three distinct parts, a head, a thorax and an abdomen.[48] The head typically bears a pair of sensory antennae, a pair of compound eyes, one to three simple eyes (ocelli) and three sets of modified appendages that form the mouthparts. The thorax has three pairs of segmented legs, one pair each for the three segments that compose the thorax and one or two pairs of wings. The abdomen is composed of eleven segments, some of which may be fused and houses the digestive, respiratory, excretory and reproductive systems.[49] There is considerable variation between species and many adaptations to the body parts, especially wings, legs, antennae and mouthparts.[50]

Spiders a class of arachnids have four pairs of legs; a body of two segmentsa cephalothorax and an abdomen. Spiders have no wings and no antennae. They have mouthparts called chelicerae which are often connected to venom glands as most spiders are venomous. They have a second pair of appendages called pedipalps attached to the cephalothorax. These have similar segmentation to the legs and function as taste and smell organs. At the end of each male pedipalp is a spoon-shaped cymbium that acts to support the copulatory organ.

Ancient Greek anatomy and physiology underwent great changes and advances throughout the early medieval world. Over time, this medical practice expanded by a continually developing understanding of the functions of organs and structures in the body. Phenomenal anatomical observations of the human body were made, which have contributed towards the understanding of the brain, eye, liver, reproductive organs and the nervous system.

The city of Alexandria was the stepping-stone for Greek anatomy and physiology. Alexandria not only housed the biggest library for medical records and books of the liberal arts in the world during the time of the Greeks, but was also home to many medical practitioners and philosophers. Great patronage of the arts and sciences from the Ptolemy rulers helped raise Alexandria up, further rivalling the cultural and scientific achievements of other Greek states.[52]

Some of the most striking advances in early anatomy and physiology took place in Hellenistic Alexandria.[52] Two of the most famous Greek anatomists and physiologists of the third century were Herophilus and Erasistratus. These two physicians helped pioneer human dissection for medical research. They also conducted vivisections on the cadavers of condemned criminals, which was considered taboo until the Renaissance Herophilus was recognized as the first person to perform systematic dissections.[53] Herophilus became known for his anatomical works making impressing contributions to many branches of anatomy and many other aspects of medicine.[54] Some of the works included classifying the system of the pulse, the discovery that human arteries had thicker walls then veins, and that the atria were parts of the heart. Herophiluss knowledge of the human body has provided vital input towards understanding the brain, eye, liver, reproductive organs and nervous system, and characterizing the course of disease.[55] Erasistratus accurately described the structure of the brain, including the cavities and membranes, and made a distinction between its cerebrum and cerebellum [56] During his study in Alexandria, Erasistratus was particularly concerned with studies of the circulatory and nervous systems. He was able to distinguish the sensory and the motor nerves in the human body and believed that air entered the lungs and heart, which was then carried throughout the body. His distinction between the arteries and veins the arteries carrying the air through the body, while the veins carried the blood from the heart was a great anatomical discovery. Erasistratus was also responsible for naming and describing the function of the epiglottis and the valves of the heart, including the tricuspid.[57] During the third century, Greek physicians were able to differentiate nerves from blood vessels and tendons [58] and to realize that the nerves convey neural impulses.[52] It was Herophilus who made the point that damage to motor nerves induced paralysis.[59] Herophilus named the meninges and ventricles in the brain, appreciated the division between cerebellum and cerebrum and recognized that the brain was the "seat of intellect" and not a "cooling chamber" as propounded by Aristotle [60] Herophilus is also credited with describing the optic, oculomotor, motor division of the trigeminal, facial, vestibulocochlear and hypoglossal nerves [61]

Great feats were made during the third century in both the digestive and reproductive systems. Herophilus was able to discover and describe not only the salivary glands, but the small intestine and liver.[61] He showed that the uterus is a hollow organ and described the ovaries and uterine tubes. He recognized that spermatozoa were produced by the testes and was the first to identify the prostate gland.[61]

In 1600 BCE, the Edwin Smith Papyrus, an Ancient Egyptian medical text, described the heart, its vessels, liver, spleen, kidneys, hypothalamus, uterus and bladder, and showed the blood vessels diverging from the heart. The Ebers Papyrus (c. 1550 BCE) features a "treatise on the heart", with vessels carrying all the body's fluids to or from every member of the body.[62]

The anatomy of the muscles and skeleton is described in the Hippocratic Corpus, an Ancient Greek medical work written by unknown authors.[63]Aristotle described vertebrate anatomy based on animal dissection. Praxagoras identified the difference between arteries and veins. Also in the 4th century BCE, Herophilos and Erasistratus produced more accurate anatomical descriptions based on vivisection of criminals in Alexandria during the Ptolemaic dynasty.[64][65]

In the 2nd century, Galen of Pergamum, an anatomist, clinician, writer and philosopher,[66] wrote the final and highly influential anatomy treatise of ancient times.[67] He compiled existing knowledge and studied anatomy through dissection of animals.[66] He was one of the first experimental physiologists through his vivisection experiments on animals.[68] Galen's drawings, based mostly on dog anatomy, became effectively the only anatomical textbook for the next thousand years.[69] His work was known to Renaissance doctors only through Islamic Golden Age medicine until it was translated from the Greek some time in the 15th century.[69]

Anatomy developed little from classical times until the sixteenth century; as the historian Marie Boas writes, "Progress in anatomy before the sixteenth century is as mysteriously slow as its development after 1500 is startlingly rapid".[69]:120121 Between 1275 and 1326, the anatomists Mondino de Luzzi, Alessandro Achillini and Antonio Benivieni at Bologna carried out the first systematic human dissections since ancient times.[70][71][72] Mondino's Anatomy of 1316 was the first textbook in the medieval rediscovery of human anatomy. It describes the body in the order followed in Mondino's dissections, starting with the abdomen, then the thorax, then the head and limbs. It was the standard anatomy textbook for the next century.[69]

Leonardo da Vinci (14521519) was trained in anatomy by Andrea del Verrocchio.[69] He made use of his anatomical knowledge in his artwork, making many sketches of skeletal structures, muscles and organs of humans and other vertebrates that he dissected.[69][73]

Andreas Vesalius (15141564) (Latinized from Andries van Wezel), professor of anatomy at the University of Padua, is considered the founder of modern human anatomy.[74] Originally from Brabant, Vesalius published the influential book De humani corporis fabrica ("the structure of the human body"), a large format book in seven volumes, in 1543.[75] The accurate and intricately detailed illustrations, often in allegorical poses against Italianate landscapes, are thought to have been made by the artist Jan van Calcar, a pupil of Titian.[76]

In England, anatomy was the subject of the first public lectures given in any science; these were given by the Company of Barbers and Surgeons in the 16th century, joined in 1583 by the Lumleian lectures in surgery at the Royal College of Physicians.[77]

In the United States, medical schools began to be set up towards the end of the 18th century. Classes in anatomy needed a continual stream of cadavers for dissection and these were difficult to obtain. Philadelphia, Baltimore and New York were all renowned for body snatching activity as criminals raided graveyards at night, removing newly buried corpses from their coffins.[78] A similar problem existed in Britain where demand for bodies became so great that grave-raiding and even anatomy murder were practised to obtain cadavers.[79] Some graveyards were in consequence protected with watchtowers. The practice was halted in Britain by the Anatomy Act of 1832,[80][81] while in the United States, similar legislation was enacted after the physician William S. Forbes of Jefferson Medical College was found guilty in 1882 of "complicity with resurrectionists in the despoliation of graves in Lebanon Cemetery".[82]

The teaching of anatomy in Britain was transformed by Sir John Struthers, Regius Professor of Anatomy at the University of Aberdeen from 1863 to 1889. He was responsible for setting up the system of three years of "pre-clinical" academic teaching in the sciences underlying medicine, including especially anatomy. This system lasted until the reform of medical training in 1993 and 2003. As well as teaching, he collected many vertebrate skeletons for his museum of comparative anatomy, published over 70 research papers, and became famous for his public dissection of the Tay Whale.[83][84] From 1822 the Royal College of Surgeons regulated the teaching of anatomy in medical schools.[85] Medical museums provided examples in comparative anatomy, and were often used in teaching.[86]Ignaz Semmelweis investigated puerperal fever and he discovered how it was caused. He noticed that the frequently fatal fever occurred more often in mothers examined by medical students than by midwives. The students went from the dissecting room to the hospital ward and examined women in childbirth. Semmelweis showed that when the trainees washed their hands in chlorinated lime before each clinical examination, the incidence of puerperal fever among the mothers could be reduced dramatically.[87]

Before the era of modern medical procedures, the main means for studying the internal structure of the body were palpation and dissection. It was the advent of microscopy that opened up an understanding of the building blocks that constituted living tissues. Technical advances in the development of achromatic lenses increased the resolving power of the microscope and around 1839, Matthias Jakob Schleiden and Theodor Schwann identified that cells were the fundamental unit of organization of all living things. Study of small structures involved passing light through them and the microtome was invented to provide sufficiently thin slices of tissue to examine. Staining techniques using artificial dyes were established to help distinguish between different types of tissue. The fields of cytology and histology developed from here in the late 19th century.[88] The invention of the electron microscope brought a great advance in resolution power and allowed research into the ultrastructure of cells and the organelles and other structures within them. About the same time, in the 1950s, the use of X-ray diffraction for studying the crystal structures of proteins, nucleic acids and other biological molecules gave rise to a new field of molecular anatomy.[88]

Short wavelength electromagnetic radiation such as X-rays can be passed through the body and used in medical radiography to view interior structures that have different degrees of opaqueness. Nowadays, modern techniques such as magnetic resonance imaging, computed tomography, fluoroscopy and ultrasound imaging have enabled researchers and practitioners to examine organs, living or dead, in unprecedented detail. They are used for diagnostic and therapeutic purposes and provide information on the internal structures and organs of the body to a degree far beyond the imagination of earlier generations.[89]

Main article: Bibliography of anatomy

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What is physiology? | Physiological Society

Physiology is the study of how molecules, cells and organs interact to form a whole being. The work of Physiological Society Members, advancing our knowledge of biological systems, is essential to the development of new treatments for disease.Since The Society's foundation in 1876, our membership has included more than 20 Nobel Prize winners from Ivan Pavlov to Andrew Huxley. The scientists who make up The Society have made many key discoveries, ranging from how our nervous system works,how our cells divide andthe way in which our reflexes alter our behaviour. These have advanced our knowledge of biological systems and helped in the treatment of diseases such as cancer, cystic fibrosis and heart disease.

As well as supporting those active in physiology research, we also work to inspire the next generations of physiologists; working with teachers, lecturers and students to help highlight physiology as a relevant, engaging career choice. The Society's presence at public events such as science fairs and media promotion of the research it publishes in its journals, also aim to raise the profile of physiology and highlight its relevance to everyday life.

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Embryology – Wikipedia

This article is about the development of embryos in animals. For the development of plant embryos, see Sporophyte.

Embryology (from Greek , embryon, "the unborn, embryo"; and -, -logia) is the branch of biology that studies the development of gametes (sex cells), fertilization, and development of embryos and fetuses. Additionally, embryology is the study of congenital disorders that occur before birth.[1]

After cleavage, the dividing cells, or morula, becomes a hollow ball, or blastula, which develops a hole or pore at one end.

In bilateral animals, the blastula develops in one of two ways that divides the whole animal kingdom into two halves (see: Embryological origins of the mouth and anus). If in the blastula the first pore (blastopore) becomes the mouth of the animal, it is a protostome; if the first pore becomes the anus then it is a deuterostome. The protostomes include most invertebrate animals, such as insects, worms and molluscs, while the deuterostomes include the vertebrates. In due course, the blastula changes into a more differentiated structure called the gastrula.

The gastrula with its blastopore soon develops three distinct layers of cells (the germ layers) from which all the bodily organs and tissues then develop:

Embryos in many species often appear similar to one another in early developmental stages. The reason for this similarity is because species have a shared evolutionary history. These similarities among species are called homologous structures, which are structures that have the same or similar function and mechanism, having evolved from a common ancestor.

Click here to read the main article on Drosophila embryogenesis

Drosophila melanogaster, a fruit fly, is a model organism in biology on which much research into embryology has been done (see figure 1.1.1A and figure 1.1.1B).[2] Before fertilization, the female gamete produces an abundance of mRNA - transcribed from the genes that encode bicoid protein and nanos protein.[3][4] These mRNA molecules are stored to be used later in what will become a developing embryo. The male and female Drosophila gametes exhibit anisogamy (differences in morphology and sub-cellular biochemistry). The female gamete is larger than the male gamete because it harbors more cytoplasm and, within the cytoplasm, the female gamete contains an abundance of the mRNA previously mentioned.[5][6] At fertilization, the male and female gametes fuse (plasmogamy) and then the nucleus of the male gamete fuses with the nucleus of the female gamete (karyogamy). Note that before the gametes' nuclei fuse, they are known as pronuclei.[7] A series of nuclear divisions will occur without cytokinesis (division of the cell) in the zygote to form a multi-nucleated cell (a cell containing multiple nuclei) known as a syncytium.[8][9] All the nuclei in the syncytium are identical, just as all the nuclei in every somatic cell of any multicellular organism are identical in terms of the DNA sequence of the genome.[10] Before the nuclei can differentiate in transcriptional activity, the embryo (syncytium) must be divided into segments. In each segment, a unique set of regulatory proteins will cause specific genes in the nuclei to be transcribed. The resulting combination of proteins will transform clusters of cells into early embryo tissues that will each develop into multiple fetal and adult tissues later in development (note: this happens after each nucleus becomes wrapped with its own cell membrane).

Outlined below is the process that leads to cell and tissue differentiation.

Maternal-effect genes - subject to Maternal (cytoplasmic) inheritance.

Zygotic-effect genes - subject to Mendelian (classical) inheritance.

Humans are bilaterals and deuterostomes.

In humans, the term embryo refers to the ball of dividing cells from the moment the zygote implants itself in the uterus wall until the end of the eighth week after conception. Beyond the eighth week after conception (tenth week of pregnancy), the developing human is then called a fetus.

As recently as the 18th century, the prevailing notion in western human embryology was preformation: the idea that semen contains an embryo a preformed, miniature infant, or homunculus that simply becomes larger during development. The competing explanation of embryonic development was epigenesis, originally proposed 2,000 years earlier by Aristotle. Much early embryology came from the work of the Italian anatomists Aldrovandi, Aranzio, Leonardo da Vinci, Marcello Malpighi, Gabriele Falloppio, Girolamo Cardano, Emilio Parisano, Fortunio Liceti, Stefano Lorenzini, Spallanzani, Enrico Sertoli, and Mauro Rusconi.[22] According to epigenesis, the form of an animal emerges gradually from a relatively formless egg. As microscopy improved during the 19th century, biologists could see that embryos took shape in a series of progressive steps, and epigenesis displaced preformation as the favoured explanation among embryologists.[23]

Karl Ernst von Baer and Heinz Christian Pander proposed the germ layer theory of development; von Baer discovered the mammalian ovum in 1827.[24][25][26] Modern embryological pioneers include Charles Darwin, Ernst Haeckel, J.B.S. Haldane, and Joseph Needham. Other important contributors include William Harvey, Kaspar Friedrich Wolff, Heinz Christian Pander, August Weismann, Gavin de Beer, Ernest Everett Just, and Edward B. Lewis.

After the 1950s, with the DNA helical structure being unravelled and the increasing knowledge in the field of molecular biology, developmental biology emerged as a field of study which attempts to correlate the genes with morphological change, and so tries to determine which genes are responsible for each morphological change that takes place in an embryo, and how these genes are regulated.

Many principles of embryology apply to invertebrates as well as to vertebrates.[27] Therefore, the study of invertebrate embryology has advanced the study of vertebrate embryology. However, there are many differences as well. For example, numerous invertebrate species release a larva before development is complete; at the end of the larval period, an animal for the first time comes to resemble an adult similar to its parent or parents. Although invertebrate embryology is similar in some ways for different invertebrate animals, there are also countless variations. For instance, while spiders proceed directly from egg to adult form, many insects develop through at least one larval stage.

Currently, embryology has become an important research area for studying the genetic control of the development process (e.g. morphogens), its link to cell signalling, its importance for the study of certain diseases and mutations, and in links to stem cell research.

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Psychology – Wikipedia, the free encyclopedia

Psychology is the study of behavior and mind, embracing all aspects of conscious and unconscious experience as well as thought. It is an academic discipline and a social science which seeks to understand individuals and groups by establishing general principles and researching specific cases.[1][2] In this field, a professional practitioner or researcher is called a psychologist and can be classified as a social, behavioral, or cognitive scientist. Psychologists attempt to understand the role of mental functions in individual and social behavior, while also exploring the physiological and biological processes that underlie cognitive functions and behaviors.

Psychologists explore behavior and mental processes, including perception, cognition, attention, emotion (affect), intelligence, phenomenology, motivation (conation), brain functioning, and personality. This extends to interaction between people, such as interpersonal relationships, including psychological resilience, family resilience, and other areas. Psychologists of diverse orientations also consider the unconscious mind.[3] Psychologists employ empirical methods to infer causal and correlational relationships between psychosocial variables. In addition, or in opposition, to employing empirical and deductive methods, someespecially clinical and counseling psychologistsat times rely upon symbolic interpretation and other inductive techniques. Psychology has been described as a "hub science",[4] with psychological findings linking to research and perspectives from the social sciences, natural sciences, medicine, humanities, and philosophy.

While psychological knowledge is often applied to the assessment and treatment of mental health problems, it is also directed towards understanding and solving problems in several spheres of human activity. By many accounts psychology ultimately aims to benefit society.[5][6] The majority of psychologists are involved in some kind of therapeutic role, practicing in clinical, counseling, or school settings. Many do scientific research on a wide range of topics related to mental processes and behavior, and typically work in university psychology departments or teach in other academic settings (e.g., medical schools, hospitals). Some are employed in industrial and organizational settings, or in other areas[7] such as human development and aging, sports, health, and the media, as well as in forensic investigation and other aspects of law.

The word psychology derives from Greek roots meaning study of the psyche, or soul ( psukh, "breath, spirit, soul" and - -logia, "study of" or "research").[8] The Latin word psychologia was first used by the Croatian humanist and Latinist Marko Maruli in his book, Psichiologia de ratione animae humanae in the late 15th century or early 16th century.[9] The earliest known reference to the word psychology in English was by Steven Blankaart in 1694 in The Physical Dictionary which refers to "Anatomy, which treats the Body, and Psychology, which treats of the Soul."[10]

In 1890, William James defined psychology as "the science of mental life, both of its phenomena and their conditions". This definition enjoyed widespread currency for decades. However, this meaning was contested, notably by radical behaviorists such as John Watson, who in his 1913 manifesto defined the discipline of psychology as the acquisition of information useful to the control of behavior. Also since James defined it, the term more strongly connotes techniques of scientific experimentation.[11][12]Folk psychology refers to the understanding of ordinary people, as contrasted with that of psychology professionals.[13]

The ancient civilizations of Egypt, Greece, China, India, and Persia all engaged in the philosophical study of psychology. Historians note that Greek philosophers, including Thales, Plato, and Aristotle (especially in his De Anima treatise),[14] addressed the workings of the mind.[15] As early as the 4th century BC, Greek physician Hippocrates theorized that mental disorders had physical rather than supernatural causes.[16]

In China, psychological understanding grew from the philosophical works of Laozi and Confucius, and later from the doctrines of Buddhism. This body of knowledge involves insights drawn from introspection and observation, as well as techniques for focused thinking and acting. It frames the universe as a division of, and interaction between, physical reality and mental reality, with an emphasis on purifying the mind in order to increase virtue and power. An ancient text known as The Yellow Emperor's Classic of Internal Medicine identifies the brain as the nexus of wisdom and sensation, includes theories of personality based on yinyang balance, and analyzes mental disorder in terms of physiological and social disequilibria. Chinese scholarship focused on the brain advanced in the Qing Dynasty with the work of Western-educated Fang Yizhi (16111671), Liu Zhi (16601730), and Wang Qingren (17681831). Wang Qingren emphasized the importance of the brain as the center of the nervous system, linked mental disorder with brain diseases, investigated the causes of dreams and insomnia, and advanced a theory of hemispheric lateralization in brain function.[17]

Distinctions in types of awareness appear in the ancient thought of India, influenced by Hinduism. A central idea of the Upanishads is the distinction between a person's transient mundane self and their eternal unchanging soul. Divergent Hindu doctrines, and Buddhism, have challenged this hierarchy of selves, but have all emphasized the importance of reaching higher awareness. Yoga is a range of techniques used in pursuit of this goal. Much of the Sanskrit corpus was suppressed under the British East India Company followed by the British Raj in the 1800s. However, Indian doctrines influenced Western thinking via the Theosophical Society, a New Age group which became popular among Euro-American intellectuals.[18]

Psychology was a popular topic in Enlightenment Europe. In Germany, Gottfried Wilhelm Leibniz (16461716) applied his principles of calculus to the mind, arguing that mental activity took place on an indivisible continuummost notably, that among an infinity of human perceptions and desires, the difference between conscious and unconscious awareness is only a matter of degree. Christian Wolff identified psychology as its own science, writing Psychologia empirica in 1732 and Psychologia rationalis in 1734. This notion advanced further under Immanuel Kant, who established the idea of anthropology, with psychology as an important subdivision. However, Kant explicitly and notoriously rejected the idea of experimental psychology, writing that "the empirical doctrine of the soul can also never approach chemistry even as a systematic art of analysis or experimental doctrine, for in the manifold of inner observation can be separated only by mere division in thought, and cannot then be held separate and recombined at will (but still less does another thinking subject suffer himself to be experimented upon to suit our purpose), and even observation by itself already changes and displaces the state of the observed object." Having consulted philosophers Hegel and Herbart, in 1825 the Prussian state established psychology as a mandatory discipline in its rapidly expanding and highly influential educational system. However, this discipline did not yet embrace experimentation.[19] In England, early psychology involved phrenology and the response to social problems including alcoholism, violence, and the country's well-populated mental asylums.[20]

Gustav Fechner began conducting psychophysics research in Leipzig in the 1830s, articulating the principle that human perception of a stimulus varies logarithmically according to its intensity.[21] Fechner's 1860 Elements of Psychophysics challenged Kant's stricture against quantitative study of the mind.[19] In Heidelberg, Hermann von Helmholtz conducted parallel research on sensory perception, and trained physiologist Wilhelm Wundt. Wundt, in turn, came to Leipzig University, establishing the psychological laboratory which brought experimental psychology to the world. Wundt focused on breaking down mental processes into the most basic components, motivated in part by an analogy to recent advances in chemistry, and its successful investigation of the elements and structure of material.[22]Paul Flechsig and Emil Kraepelin soon created another influential psychology laboratory at Leipzig, this one focused on more on experimental psychiatry.[19]

Psychologists in Germany, Denmark, Austria, England, and the United States soon followed Wundt in setting up laboratories.[23]G. Stanley Hall who studied with Wundt, formed a psychology lab at Johns Hopkins University in Maryland, which became internationally influential. Hall, in turn, trained Yujiro Motora, who brought experimental psychology, emphasizing psychophysics, to the Imperial University of Tokyo.[24] Wundt assistant Hugo Mnsterberg taught psychology at Harvard to students such as Narendra Nath Sen Guptawho, in 1905, founded a psychology department and laboratory at the University of Calcutta.[18] Wundt students Walter Dill Scott, Lightner Witmer, and James McKeen Cattell worked on developing tests for mental ability. Catell, who also studied with eugenicist Francis Galton, went on to found the Psychological Corporation. Wittmer focused on mental testing of children; Scott, on selection of employees.[25]

Another student of Wundt, Edward Titchener, created the psychology program at Cornell University and advanced a doctrine of "structuralist" psychology. Structuralism sought to analyze and classify different aspects of the mind, primarily through the method of introspection.[26]William James, John Dewey and Harvey Carr advanced a more expansive doctrine called functionalism, attuned more to humanenvironment actions. In 1890 James wrote an influential book, The Principles of Psychology, which expanded on the realm of structuralism, memorably described the human "stream of consciousness", and interested many American students in the emerging discipline.[26][27][28] Dewey integrated psychology with social issues, most notably by promoting the cause progressive education to assimilate immigrants and inculcate moral values in children.[29]

A different strain of experimentalism, with more connection to physiology, emerged in South America, under the leadership of Horacio G. Piero at the University of Buenos Aires.[30] Russia, too, placed greater emphasis on the biological basis for psychology, beginning with Ivan Sechenov's 1873 essay, "Who Is to Develop Psychology and How?" Sechenov advanced the idea of brain reflexes and aggressively promoted a deterministic viewpoint on human behavior.[31]

Wolfgang Kohler, Max Wertheimer and Kurt Koffka co-founded the school of Gestalt psychology (not to be confused with the Gestalt therapy of Fritz Perls). This approach is based upon the idea that individuals experience things as unified wholes. Rather than breaking down thoughts and behavior into smaller elements, as in structuralism, the Gestaltists maintained that whole of experience is important, and differs from the sum of its parts. Other 19th-century contributors to the field include the German psychologist Hermann Ebbinghaus, a pioneer in the experimental study of memory, who developed quantitative models of learning and forgetting at the University of Berlin,[32] and the Russian-Soviet physiologist Ivan Pavlov, who discovered in dogs a learning process that was later termed "classical conditioning" and applied to human beings.[33]

One of the earliest psychology societies was La Socit de Psychologie Physiologique in France, which lasted 18851893. The first meeting of the International Congress of Psychology took place in Paris, in August 1889, amidst the World's Fair celebrating the centennial of the French Revolution. William James was one of three Americans among the four hundred attendees. The American Psychological Association was founded soon after, in 1892. The International Congress continued to be held, at different locations in Europe, with wider international participation. The Sixth Congress, Geneva 1909, included presentations in Russian, Chinese, and Japanese, as well as Esperanto. After a hiatus for World War I, the Seventh Congress met in Oxford, with substantially greater participation from the war-victorious Anglo-Americans. In 1929, the Congress took place at Yale University in New Haven, Connecticut, attended by hundreds of members of the American Psychological Association[23] Tokyo Imperial University led the way in bringing the new psychology to the East, and from Japan these ideas diffused into China.[17][24]

American psychology gained status during World War I, during which a standing committee headed by Robert Yerkes administered mental tests ("Army Alpha" and "Army Beta") to almost 1.8 million GIs.[34] Subsequent funding for behavioral research came in large part from the Rockefeller family, via the Social Science Research Council.[35][36] Rockefeller charities funded the National Committee on Mental Hygiene, which promoted the concept of mental illness and lobbied for psychological supervision of child development.[34][37] Through the Bureau of Social Hygiene and later funding of Alfred Kinsey, Rockefeller foundations established sex research as a viable discipline in the U.S.[38] Under the influence of the Carnegie-funded Eugenics Record Office, the Draper-funded Pioneer Fund, and other institutions, the eugenics movement also had a significant impact on American psychology; in the 1910s and 1920s, eugenics became a standard topic in psychology classes.[39]

During World War II and the Cold War, the U.S. military and intelligence agencies established themselves as leading funders of psychologythrough the armed forces and in the new Office of Strategic Services intelligence agency. University of Michigan psychologist Dorwin Cartwright reported that university researchers began large-scale propaganda research in 19391941, and "the last few months of the war saw a social psychologist become chiefly responsible for determining the week-by-week-propaganda policy for the United States Government." Cartwright also wrote that psychologists had significant roles in managing the domestic economy.[40] The Army rolled out its new General Classification Test and engaged in massive studies of troop morale. In the 1950s, the Rockefeller Foundation and Ford Foundation collaborated with the Central Intelligence Agency to fund research on psychological warfare.[41] In 1965, public controversy called attention to the Army's Project Camelotthe "Manhattan Project" of social sciencean effort which enlisted psychologists and anthropologists to analyze foreign countries for strategic purposes.[42][43]

In Germany after World War I, psychology held institutional power through the military, and subsequently expanded along with the rest of the military under the Third Reich.[19] Under the direction of Hermann Gring's cousin Matthias Gring, the Berlin Psychoanalytic Institute was renamed the Gring Institute. Freudian psychoanalysts were expelled and persecuted under the anti-Jewish policies of the Nazi Party, and all psychologists had to distance themselves from Freud and Adler.[44] The Gring Institute was well-financed throughout the war with a mandate to create a "New German Psychotherapy". This psychotherapy aimed to align suitable Germans with the overall goals of the Reich; as described by one physician: "Despite the importance of analysis, spiritual guidance and the active cooperation of the patient represent the best way to overcome individual mental problems and to subordinate them to the requirements of the Volk and the Gemeinschaft." Psychologists were to provide Seelenfhrung, leadership of the mind, to integrate people into the new vision of a German community.[45]Harald Schultz-Hencke melded psychology with the Nazi theory of biology and racial origins, criticizing psychoanalysis as a study of the weak and deformed.[46]Johannes Heinrich Schultz, a German psychologist recognized for developing the technique of autogenic training, prominently advocated sterilization and euthanasia of men considered genetically undesirable, and devised techniques for facilitating this process.[47] After the war, some new institutions were created and some psychologists were discredited due to Nazi affiliation. Alexander Mitscherlich founded a prominent applied psychoanalysis journal called Psyche and with funding from the Rockefeller Foundation established the first clinical psychosomatic medicine division at Heidelberg University. In 1970, psychology was integrated into the required studies of medical students.[48]

After the Russian Revolution, psychology was heavily promoted by the Bolsheviks as a way to engineer the "New Man" of socialism. Thus, university psychology departments trained large numbers of students, for whom positions were made available at schools, workplaces, cultural institutions, and in the military. An especial focus was pedology, the study of child development, regarding which Lev Vygotsky became a prominent writer.[31] The Bolsheviks also promoted free love and embranced the doctrine of psychoanalysis as an antidote to sexual repression.[49] Although pedology and intelligence testing fell out of favor in 1936, psychology maintained its privileged position as an instrument of the Soviet state.[31] Stalinist purges took a heavy toll and instilled a climate of fear in the profession, as elsewhere in Soviet society.[50] Following World War II, Jewish psychologists past and present (including Vygotsky, A. R. Luria, and Aron Zalkind) were denounced; Ivan Pavlov (posthumously) and Stalin himself were aggrandized as heroes of Soviet psychology.[51] Soviet academics was speedily liberalized during the Khrushchev Thaw, and cybernetics, linguistics, genetics, and other topics became acceptable again. There emerged a new field called "engineering psychology" which studied mental aspects of complex jobs (such as pilot and cosmonaut). Interdisciplinary studies became popular and scholars such as Georgy Shchedrovitsky developed systems theory approaches to human behavior.[52]

Twentieth-century Chinese psychology originally modeled the United States, with translations from American authors like William James, the establishment of university psychology departments and journals, and the establishment of groups including the Chinese Association of Psychological Testing (1930) and the Chinese Psychological Society (1937). Chinese psychologists were encouraged to focus on education and language learning, with the aspiration that education would enable modernization and nationalization. John Dewey, who lectured to Chinese audiences in 19181920, had a significant influence on this doctrine. Chancellor T'sai Yuan-p'ei introduced him at Peking University as a greater thinker than Confucius. Kuo Zing-yang who received a PhD at the University of California, Berkeley, became President of Zhejiang University and popularized behaviorism.[53] After the Chinese Communist Party gained control of the country, the Stalinist USSR became the leading influence, with MarxismLeninism the leading social doctrine and Pavlovian conditioning the approved concept of behavior change. Chinese psychologists elaborated on Lenin's model of a "reflective" consciousness, envisioning an "active consciousness" (tzu-chueh neng-tung-li) able to transcend material conditions through hard work and ideological struggle. They developed a concept of "recognition" (jen-shih) which referred the interface between individual perceptions and the socially accepted worldview. (Failure to correspond with party doctrine was "incorrect recognition".)[54] Psychology education was centralized under the Chinese Academy of Sciences, supervised by the State Council. In 1951 the Academy created a Psychology Research Office, which in 1956 became the Institute of Psychology. Most leading psychologists were educated in the United States, and the first concern of the Academy was re-education of these psychologists in the Soviet doctrines. Child psychology and pedagogy for nationally cohesive education remained a central goal of the discipline.[55]

In 1920, douard Claparde and Pierre Bovet created a new applied psychology organization called the International Congress of Psychotechnics Applied to Vocational Guidance, later called the International Congress of Psychotechnics and then the International Association of Applied Psychology.[23] The IAAP is considered the oldest international psychology association.[56] Today, at least 65 international groups deal with specialized aspects of psychology.[56] In response to male predominance in the field, female psychologists in the U.S. formed National Council of Women Psychologists in 1941. This organization became the International Council of Women Psychologists after World War II, and the International Council of Psychologists in 1959. Several associations including the Association of Black Psychologists and the Asian American Psychological Association have arisen to promote non-European racial groups in the profession.[56]

The world federation of national psychological societies is the International Union of Psychological Science (IUPsyS), founded in 1951 under the auspices of UNESCO, the United Nations cultural and scientific authority.[23][57] Psychology departments have since proliferated around the world, based primarily on the Euro-American model.[18][57] Since 1966, the Union has published the International Journal of Psychology.[23] IAAP and IUPsyS agreed in 1976 each to hold a congress every four years, on a staggered basis.[56]

The International Union recognizes 66 national psychology associations and at least 15 others exist.[56] The American Psychological Association is the oldest and largest.[56] Its membership has increased from 5,000 in 1945 to 100,000 in the present day.[26] The APA includes 54 divisions, which since 1960 have steadily proliferated to include more specialties. Some of these divisions, such as the Society for the Psychological Study of Social Issues and the American PsychologyLaw Society, began as autonomous groups.[56]

The Interamerican Society of Psychology, founded in 1951, aspires to promote psychology and coordinate psychologists across the Western Hemisphere. It holds the Interamerican Congress of Psychology and had 1000 members in year 2000. The European Federation of Professional Psychology Associations, founded in 1981, represents 30 national associations with a total of 100,000 individual members. At least 30 other international groups organize psychologists in different regions.[56]

In some places, governments legally regulate who can provide psychological services or represent themselves as a "psychologist".[58] The American Psychological Association defines a psychologist as someone with a doctoral degree in psychology.[59]

Early practitioners of experimental psychology distinguished themselves from parapsychology, which in the late nineteenth century enjoyed great popularity (including the interest of scholars such as William James), and indeed constituted the bulk of what people called "psychology". Parapsychology, hypnotism, and psychism were major topics of the early International Congresses. But students of these fields were eventually ostractized, and more or less banished from the Congress in 19001905.[23] Parapsychology persisted for a time at Imperial University, with publications such as Clairvoyance and Thoughtography by Tomokichi Fukurai, but here too it was mostly shunned by 1913.[24]

As a discipline, psychology has long sought to fend off accusations that it is a "soft" science. Philosopher of science Thomas Kuhn's 1962 critique implied psychology overall was in a pre-paradigm state, lacking the agreement on overarching theory found in mature sciences such as chemistry and physics.[60] Because some areas of psychology rely on research methods such as surveys and questionnaires, critics asserted that psychology is not an objective science. Skeptics have suggested that personality, thinking, and emotion, cannot be directly measured and are often inferred from subjective self-reports, which may be problematic. Experimental psychologists have devised a variety of ways to indirectly measure these elusive phenomenological entities.[61][62][63]

Divisions still exist within the field, with some psychologists more oriented towards the unique experiences of individual humans, which cannot be understood only as data points within a larger population. Critics inside and outside the field have argued that mainstream psychology has become increasingly dominated by a "cult of empiricism" which limits the scope of its study by using only methods derived from the physical sciences.[64] Feminist critiques along these lines have argued that claims to scientific objectivity obscure the values and agenda of (historically mostly male)[34] researchers. Jean Grimshaw, for example, argues that mainstream psychological research has advanced a patriarchal agenda through its efforts to control behavior.[65]

Psychologists generally consider the organism the basis of the mind, and therefore a vitally related area of study. Psychiatrists and neuropsychologists work at the interface of mind and body.[66] Biological psychology, also known as physiological psychology,[67] or neuropsychology is the study of the biological substrates of behavior and mental processes. Key research topics in this field include comparative psychology, which studies humans in relation to other animals, and perception which involves the physical mechanics of sensation as well as neural and mental processing.[68] For centuries, a leading question in biological psychology has been whether and how mental functions might be localized in the brain. From Phineas Gage to H. M. and Clive Wearing, individual people with mental issues traceable to physical damage have inspired new discoveries in this area.[67] Modern neuropsychology could be said to originate in the 1870s, when in France Paul Broca traced production of speech to the left frontal gyrus, thereby also demonstrating hemispheric lateralization of brain function. Soon after, Carl Wernicke identified a related area necessary for the understanding of speech.[69]

The contemporary field of behavioral neuroscience focuses on physical causes underpinning behavior. For example, physiological psychologists use animal models, typically rats, to study the neural, genetic, and cellular mechanisms that underlie specific behaviors such as learning and memory and fear responses.[70]Cognitive neuroscientists investigate the neural correlates of psychological processes in humans using neural imaging tools, and neuropsychologists conduct psychological assessments to determine, for instance, specific aspects and extent of cognitive deficit caused by brain damage or disease. The biopsychosocial model is an integrated perspective toward understanding consciousness, behavior, and social interaction. It assumes that any given behavior or mental process affects and is affected by dynamically interrelated biological, psychological, and social factors.[71]

Evolutionary psychology examines cognition and personality traits from an evolutionary perspective. This perspective suggests that psychological adaptations evolved to solve recurrent problems in human ancestral environments. Evolutionary psychology offers complementary explanations for the mostly proximate or developmental explanations developed by other areas of psychology: that is, it focuses mostly on ultimate or "why?" questions, rather than proximate or "how?" questions. "How?" questions are more directly tackled by behavioral genetics research, which aims to understand how genes and environment impact behavior.[72]

The search for biological origins of psychological phenomena has long involved debates about the importance of race, and especially the relationship between race and intelligence. The idea of white supremacy and indeed the modern concept of race itself arose during the process of world conquest by Europeans.[73]Carl von Linnaeus's four-fold classification of humans classifies Europeans as intelligent and severe, Americans as contented and free, Asians as ritualistic, and Africans as lazy and capricious. Race was also used to justify the construction of socially specific mental disorders such as drapetomania and dysaesthesia aethiopicathe behavior of uncooperative African slaves.[74] After the creation of experimental psychology, "ethnical psychology" emerged as a subdiscipline, based on the assumption that studying primitive races would provide an important link between animal behavior and the psychology of more evolved humans.[75]

Psychologists take human behavior as a main area of study. Much of the research in this area began with tests on mammals, based on the idea that humans exhibit similar fundamental tendencies. Behavioral research ever aspires to improve the effectiveness of techniques for behavior modification.

Early behavioral researchers studied stimulusresponse pairings, now known as classical conditioning. They demonstrated that behaviors could be linked through repeated association with stimuli eliciting pain or pleasure. Ivan Pavlovknown best for inducing dogs to salivate in the presence of a stimulus previous linked with foodbecame a leading figure in the Soviet Union and inspired followers to use his methods on humans.[31] In the United States, Edward Lee Thorndike initiated "connectionism" studies by trapping animals in "puzzle boxes" and rewarding them for escaping. Thorndike wrote in 1911: "There can be no moral warrant for studying man's nature unless the study will enable us to control his acts."[76] From 19101913 the American Psychological Association went through a sea change of opinion, away from mentalism and towards "behavioralism", and in 1913 John B. Watson coined the term behaviorism for this school of thought.[77] Watson's famous Little Albert experiment in 1920 demonstrated that repeated use of upsetting loud noises could instill phobias (aversions to other stimuli) in an infant human.[12][78]Karl Lashley, a close collaborator with Watson, examined biological manifestations of learning in the brain.[67]

Embraced and extended by Clark L. Hull, Edwin Guthrie, and others, behaviorism became a widely used research paradigm.[26] A new method of "instrumental" or "operant" conditioning added the concepts of reinforcement and punishment to the model of behavior change. Radical behaviorists avoided discussing the inner workings of the mind, especially the unconscious mind, which they considered impossible to assess scientifically.[79] Operant conditioning was first described by Miller and Kanorski and popularized in the U.S. by B. F. Skinner, who emerged as a leading intellectual of the behaviorist movement.[80][81]

Noam Chomsky delivered an influential critique of radical behaviorism on the grounds that it could not adequately explain the complex mental process of language acquisition.[82][83][84]Martin Seligman and colleagues discovered that the conditioning of dogs led to outcomes ("learned helplessness") that opposed the predictions of behaviorism.[85][86] Skinner's behaviorism did not die, perhaps in part because it generated successful practical applications.[82]Edward C. Tolman advanced a hybrid "cognitive behaviorial" model, most notably with his 1948 publication discussing the cognitive maps used by rats to guess at the location of food at the end of a modified maze.[87]

The Association for Behavior Analysis International was founded in 1974 and by 2003 had members from 42 countries. The field has been especially influential in Latin America, where it has a regional organization known as ALAMOC: La Asociacin Latinoamericana de Anlisis y Modificacin del Comportamiento. Behaviorism also gained a strong foothold in Japan, where it gave rise to the Japanese Society of Animal Psychology (1933), the Japanese Association of Special Education (1963), the Japanese Society of Biofeedback Research (1973), the Japanese Association for Behavior Therapy (1976), the Japanese Association for Behavior Analysis (1979), and the Japanese Association for Behavioral Science Research (1994).[88] Today the field of behaviorism is also commonly referred to as behavior modification or behavior analysis.[88]

Green Red Blue Purple Blue Purple

Blue Purple Red Green Purple Green

The Stroop effect refers to the fact that naming the color of the first set of words is easier and quicker than the second.

Cognitive psychology studies cognition, the mental processes underlying mental activity. Perception, attention, reasoning, thinking, problem solving, memory, learning, language, and emotion are areas of research. Classical cognitive psychology is associated with a school of thought known as cognitivism, whose adherents argue for an information processing model of mental function, informed by functionalism and experimental psychology.

On a broader level, cognitive science is an interdisciplinary enterprise of cognitive psychologists, cognitive neuroscientists, researchers in artificial intelligence, linguists, humancomputer interaction, computational neuroscience, logicians and social scientists. Computer simulations are sometimes used to model phenomena of interest.

Starting in the 1950s, the experimental techniques developed by Wundt, James, Ebbinghaus, and others re-emerged as experimental psychology became increasingly cognitivistconcerned with information and its processingand, eventually, constituted a part of the wider cognitive science.[89] Some called this development the cognitive revolution because it rejected the anti-mentalist dogma of behaviorism as well as the strictures of psychoanalysis.[89]

Social learning theorists, such as Albert Bandura, argued that the child's environment could make contributions of its own to the behaviors of an observant subject.[90]

Technological advances also renewed interest in mental states and representations. English neuroscientist Charles Sherrington and Canadian psychologist Donald O. Hebb used experimental methods to link psychological phenomena with the structure and function of the brain. The rise of computer science, cybernetics and artificial intelligence suggested the value of comparatively studying information processing in humans and machines. Research in cognition had proven practical since World War II, when it aided in the understanding of weapons operation.[91]

A popular and representative topic in this area is cognitive bias, or irrational thought. Psychologists (and economists) have classified and described a sizeable catalogue of biases which recur frequently in human thought. The availability heuristic, for example, is the tendency to overestimate the importance of something which happens to come readily to mind.

Elements of behaviorism and cognitive psychology were synthesized to form cognitive behavioral therapy, a form of psychotherapy modified from techniques developed by American psychologist Albert Ellis and American psychiatrist Aaron T. Beck. Cognitive psychology was subsumed along with other disciplines, such as philosophy of mind, computer science, and neuroscience, under the cover discipline of cognitive science.

Social psychology is the study of how humans think about each other and how they relate to each other. Social psychologists study such topics as the influence of others on an individual's behavior (e.g. conformity, persuasion), and the formation of beliefs, attitudes, and stereotypes about other people. Social cognition fuses elements of social and cognitive psychology in order to understand how people process, remember, or distort social information. The study of group dynamics reveals information about the nature and potential optimization of leadership, communication, and other phenomena that emerge at least at the microsocial level. In recent years, many social psychologists have become increasingly interested in implicit measures, mediational models, and the interaction of both person and social variables in accounting for behavior. The study of human society is therefore a potentially valuable source of information about the causes of psychiatric disorder. Some sociological concepts applied to psychiatric disorders are the social role, sick role, social class, life event, culture, migration, social, and total institution.

Psychoanalysis comprises a method of investigating the mind and interpreting experience; a systematized set of theories about human behavior; and a form of psychotherapy to treat psychological or emotional distress, especially conflict originating in the unconscious mind.[92] This school of thought originated in the 1890s with Austrian medical doctors including Josef Breuer (physician), Alfred Adler (physician), Otto Rank (psychoanalyst), and most prominently Sigmund Freud (neurologist). Freud's psychoanalytic theory was largely based on interpretive methods, introspection and clinical observations. It became very well known, largely because it tackled subjects such as sexuality, repression, and the unconscious. These subjects were largely taboo at the time, and Freud provided a catalyst for their open discussion in polite society.[49] Clinically, Freud helped to pioneer the method of free association and a therapeutic interest in dream interpretation.[93][94]

Swiss psychiatrist Carl Jung, influenced by Freud, elaborated a theory of the collective unconsciousa primordial force present in all humans, featuring archetypes which exerted a profound influence on the mind. Jung's competing vision formed the basis for analytical psychology, which later led to the archetypal and process-oriented schools. Other well-known psychoanalytic scholars of the mid-20th century include Erik Erikson, Melanie Klein, D. W. Winnicott, Karen Horney, Erich Fromm, John Bowlby, and Sigmund Freud's daughter, Anna Freud. Throughout the 20th century, psychoanalysis evolved into diverse schools of thought which could be called Neo-Freudian. Among these schools are ego psychology, object relations, and interpersonal, Lacanian, and relational psychoanalysis.

Psychologists such as Hans Eysenck and philosophers including Karl Popper criticized psychoanalysis. Popper argued that psychoanalysis had been misrepresented as a scientific discipline,[95] whereas Eysenck said that psychoanalytic tenets had been contradicted by experimental data. By the end of 20th century, psychology departments in American universities mostly marginalized Freudian theory, dismissing it as a "desiccated and dead" historical artifact.[96] However, researchers in the emerging field of neuro-psychoanalysis today defend some of Freud's ideas on scientific grounds,[97] while scholars of the humanities maintain that Freud was not a "scientist at all, but ... an interpreter".[96]

Humanistic psychology developed in the 1950s as a movement within academic psychology, in reaction to both behaviorism and psychoanalysis.[99] The humanistic approach sought to glimpse the whole person, not just fragmented parts of the personality or isolated cognitions.[100] Humanism focused on uniquely human issues, such as free will, personal growth, self-actualization, self-identity, death, aloneness, freedom, and meaning. It emphasized subjective meaning, rejection of determinism, and concern for positive growth rather than pathology.[citation needed] Some founders of the humanistic school of thought were American psychologists Abraham Maslow, who formulated a hierarchy of human needs, and Carl Rogers, who created and developed client-centered therapy. Later, positive psychology opened up humanistic themes to scientific modes of exploration.

The American Association for Humanistic Psychology, formed in 1963, declared:

Humanistic psychology is primarily an orientation toward the whole of psychology rather than a distinct area or school. It stands for respect for the worth of persons, respect for differences of approach, open-mindedness as to acceptable methods, and interest in exploration of new aspects of human behavior. As a "third force" in contemporary psychology, it is concerned with topics having little place in existing theories and systems: e.g., love, creativity, self, growth, organism, basic need-gratification, self-actualization, higher values, being, becoming, spontaneity, play, humor, affection, naturalness, warmth, ego-transcendence, objectivity, autonomy, responsibility, meaning, fair-play, transcendental experience, peak experience, courage, and related concepts.[101]

In the 1950s and 1960s, influenced by philosophers Sren Kierkegaard and Martin Heidegger and, psychoanalytically trained American psychologist Rollo May pioneered an existential branch of psychology, which included existential psychotherapy: a method based on the belief that inner conflict within a person is due to that individual's confrontation with the givens of existence. Swiss psychoanalyst Ludwig Binswanger and American psychologist George Kelly may also be said to belong to the existential school.[102] Existential psychologists differed from more "humanistic" psychologists in their relatively neutral view of human nature and their relatively positive assessment of anxiety.[103] Existential psychologists emphasized the humanistic themes of death, free will, and meaning, suggesting that meaning can be shaped by myths, or narrative patterns,[104] and that it can be encouraged by an acceptance of the free will requisite to an authentic, albeit often anxious, regard for death and other future prospects.

Austrian existential psychiatrist and Holocaust survivor Viktor Frankl drew evidence of meaning's therapeutic power from reflections garnered from his own internment.[105] He created a variation of existential psychotherapy called logotherapy, a type of existentialist analysis that focuses on a will to meaning (in one's life), as opposed to Adler's Nietzschean doctrine of will to power or Freud's will to pleasure.[106]

Personality psychology is concerned with enduring patterns of behavior, thought, and emotioncommonly referred to as personalityin individuals. Theories of personality vary across different psychological schools and orientations. They carry different assumptions about such issues as the role of the unconscious and the importance of childhood experience. According to Freud, personality is based on the dynamic interactions of the id, ego, and super-ego.[107]Trait theorists, in contrast, attempt to analyze personality in terms of a discrete number of key traits by the statistical method of factor analysis. The number of proposed traits has varied widely. An early model, proposed by Hans Eysenck, suggested that there are three traits which comprise human personality: extraversionintroversion, neuroticism, and psychoticism. Raymond Cattell proposed a theory of 16 personality factors. Dimensional models of personality are receiving increasing support, and some version of dimensional assessment will be included in the forthcoming DSM-V.

Myriad approach to systematically assess different personality types, with the Woodworth Personal Data Sheet, developed during World War I, an early example of the modern technique. The MyersBriggs Type Indicator sought to assess people according to the personality theories of Carl Jung. Behaviorist resistance to introspection led to the development of the Strong Vocational Interest Blank and Minnesota Multiphasic Personality Inventory, tests which ask more empirical questions and focus less on the psychodynamics of the respondent.[108]

Study of the unconscious mind, a part of the psyche outside the awareness of the individual which nevertheless influenced thoughts and behavior was a hallmark of early psychology. In one of the first psychology experiments conducted in the United States, C. S. Peirce and Joseph Jastrow found in 1884 that subjects could choose the minutely heavier of two weights even if consciously uncertain of the difference.[109] Freud popularized this concept, with terms like Freudian slip entering popular culture, to mean an uncensored intrusion of unconscious thought into one's speech and action. His 1901 text The Psychopathology of Everyday Life catalogues hundreds of everyday events which Freud explains in terms of unconscious influence. Pierre Janet advanced the idea of a subconscious mind, which could contain autonomous mental elements unavailable to the scrutiny of the subject.[110]

Behaviorism notwithstanding, the unconscious mind has maintained its importance in psychology. Cognitive psychologists have used a "filter" model of attention, according to which much information processing takes place below the threshold of consciousness, and only certain processes, limited by nature and by simultaneous quantity, make their way through the filter. Copious research has shown that subconscious priming of certain ideas can covertly influence thoughts and behavior.[110] A significant hurdle in this research is proving that a subject's conscious mind has not grasped a certain stimulus, due to the unreliability of self-reporting. For this reason, some psychologists prefer to distinguish between implicit and explicit memory. In another approach, one can also describe a subliminal stimulus as meeting an objective but not a subjective threshold.[111]

The automaticity model, which became widespread following exposition by John Bargh and others in the 1980s, describes sophisticated processes for executing goals which can be selected and performed over an extended duration without conscious awareness.[112][113] Some experimental data suggests that the brain begins to consider taking actions before the mind becomes aware of them.[111][114] This influence of unconscious forces on people's choices naturally bears on philosophical questions free will. John Bargh, Daniel Wegner, and Ellen Langer are some prominent contemporary psychologists who describe free will as an illusion.[112][113][115]

Psychologists such as William James initially used the term motivation to refer to intention, in a sense similar to the concept of will in European philosophy. With the steady rise of Darwinian and Freudian thinking, instinct also came to be seen as a primary source of motivation.[116] According to drive theory, the forces of instinct combine into a single source of energy which exerts a constant influence. Psychoanalysis, like biology, regarded these forces as physical demands made by the organism on the nervous system. However, they believed that these forces, especially the sexual instincts, could become entangled and transmuted within the psyche. Classical psychoanalysis conceives of a struggle between the pleasure principle and the reality principle, roughly corresponding to id and ego. Later, in Beyond the Pleasure Principle, Freud introduced the concept of the death drive, a compulsion towards aggression, destruction, and psychic repetition of traumatic events.[117] Meanwhile, behaviorist researchers used simple dichotomous models (pleasure/pain, reward/punishment) and well-established principles such as the idea that a thirsty creature will take pleasure in drinking.[116][118]Clark Hull formalized the latter idea with his drive reduction model.[119]

Hunger, thirst, fear, sexual desire, and thermoregulation all seem to constitute fundamental motivations for animals.[118] Humans also seem to exhibit a more complex set of motivationsthough theoretically these could be explained as resulting from primordial instinctsincluding desires for belonging, self-image, self-consistency, truth, love, and control.[120][121]

Motivation can be modulated or manipulated in many different ways. Researchers have found that eating, for example, depends not only on the organism's fundamental need for homeostasisan important factor causing the experience of hungerbut also on circadian rhythms, food availability, food palatability, and cost.[118] Abstract motivations are also malleable, as evidenced by such phenomena as goal contagion: the adoption of goals, sometimes unconsciously, based on inferences about the goals of others.[122] Vohs and Baumeister suggest that contrary to the need-desire-fulfilment cycle of animal instincts, human motivations sometimes obey a "getting begets wanting" rule: the more you get a reward such as self-esteem, love, drugs, or money, the more you want it. They suggest that this principle can even apply to food, drink, sex, and sleep.[123]

Mainly focusing on the development of the human mind through the life span, developmental psychology seeks to understand how people come to perceive, understand, and act within the world and how these processes change as they age. This may focus on cognitive, affective, moral, social, or neural development. Researchers who study children use a number of unique research methods to make observations in natural settings or to engage them in experimental tasks. Such tasks often resemble specially designed games and activities that are both enjoyable for the child and scientifically useful, and researchers have even devised clever methods to study the mental processes of infants. In addition to studying children, developmental psychologists also study aging and processes throughout the life span, especially at other times of rapid change (such as adolescence and old age). Developmental psychologists draw on the full range of psychological theories to inform their research.

All researched psychological traits are influenced by both genes and environment, to varying degrees.[124][125] These two sources of influence are often confounded in observational research of individuals or families. An example is the transmission of depression from a depressed mother to her offspring. Theory may hold that the offspring, by virtue of having a depressed mother in his or her (the offspring's) environment, is at risk for developing depression. However, risk for depression is also influenced to some extent by genes. The mother may both carry genes that contribute to her depression but will also have passed those genes on to her offspring thus increasing the offspring's risk for depression. Genes and environment in this simple transmission model are completely confounded. Experimental and quasi-experimental behavioral genetic research uses genetic methodologies to disentangle this confound and understand the nature and origins of individual differences in behavior.[72] Traditionally this research has been conducted using twin studies and adoption studies, two designs where genetic and environmental influences can be partially un-confounded. More recently, the availability of microarray molecular genetic or genome sequencing technologies allows researchers to measure participant DNA variation directly, and test whether individual genetic variants within genes are associated with psychological traits and psychopathology through methods including genome-wide association studies. One goal of such research is similar to that in positional cloning and its success in Huntington's: once a causal gene is discovered biological research can be conducted to understand how that gene influences the phenotype. One major result of genetic association studies is the general finding that psychological traits and psychopathology, as well as complex medical diseases, are highly polygenic,[126][127][128][129][130] where a large number (on the order of hundreds to thousands) of genetic variants, each of small effect, contribute to individual differences in the behavioral trait or propensity to the disorder. Active research continues to understand the genetic and environmental bases of behavior and their interaction.

Psychology encompasses many subfields and includes different approaches to the study of mental processes and behavior:

Psychological testing has ancient origins, such as examinations for the Chinese civil service dating back to 2200 BC. Written exams began during the Han dynasty (202 BC.AD. 200). By 1370, the Chinese system required a stratified series of tests, involving essay writing and knowledge of diverse topics. The system was ended in 1906.[131] In Europe, mental assessment took a more physiological approach, with theories of physiognomyjudgment of character based on the facedescribed by Aristotle in 4th century BC Greece. Physiognomy remained current through the Enlightenment, and added the doctrine of phrenology: a study of mind and intelligence based on simple assessment of neuroanatomy.[132]

When experimental psychology came to Britain, Francis Galton was a leading practitioner, and, with his procedures for measuring reaction time and sensation, is considered an inventor of modern mental testing (also known as psychometrics).[133]James McKeen Cattell, a student of Wundt and Galton, brought the concept to the United States, and in fact coined the term "mental test".[134] In 1901, Cattell's student Clark Wissler published discouraging results, suggesting that mental testing of Columbia and Barnard students failed to predict their academic performance.[134] In response to 1904 orders from the Minister of Public Instruction, French psychologists Alfred Binet and Thodore Simon elaborated a new test of intelligence in 19051911, using a range of questions diverse in their nature and difficulty. Binet and Simon introduced the concept of mental age and referred to the lowest scorers on their test as idiots. Henry H. Goddard put the Binet-Simon scale to work and introduced classifications of mental level such as imbecile and feebleminded. In 1916 (after Binet's death), Stanford professor Lewis M. Terman modified the Binet-Simon scale (renamed the StanfordBinet scale) and introduced the intelligence quotient as a score report.[135] From this test, Terman concluded that mental retardation "represents the level of intelligence which is very, very common among Spanish-Indians and Mexican families of the Southwest and also among negroes. Their dullness seems to be racial."[136]

Following the Army Alpha and Army Beta tests for soldiers in World War I, mental testing became popular in the US, where it was soon applied to school children. The federally created National Intelligence Test was administered to 7 million children in the 1920s, and in 1926 the College Entrance Examination Board created the Scholastic Aptitude Test to standardize college admissions.[137] The results of intelligence tests were used to argue for segregated schools and economic functionsi.e. the preferential training of Black Americans for manual labor. These practices were criticized by black intellectuals such a Horace Mann Bond and Allison Davis.[136] Eugenicists used mental testing to justify and organize compulsory sterilization of individuals classified as mentally retarded.[39] In the United States, tens of thousands of men and women were sterilized. Setting a precedent which has never been overturned, the U.S. Supreme Court affirmed the constitutionality of this practice in the 1907 case Buck v. Bell.[138]

Today mental testing is a routine phenomenon for people of all ages in Western societies.[139] Modern testing aspires to criteria including standardization of procedure, consistency of results, output of an interpretable score, statistical norms describing population outcomes, and, ideally, effective prediction of behavior and life outcomes outside of testing situations.[140]

The provision of psychological health services is generally called clinical psychology in the U.S. The definitions of this term are various and may include school psychology and counseling psychology. Practitioners typically includes people who have graduated from doctoral programs in clinical psychology but may also include others. In Canada, the above groups usually fall within the larger category of professional psychology. In Canada and the US, practitioners get bachelor's degrees and doctorates, then spend one year in an internship and one year in postdoctoral education. In Mexico and most other Latin American and European countries, psychologists do not get bachelor's and doctorate degrees; instead, they take a three-year professional course following high school.[59] Clinical psychology is at present the largest specialization within psychology.[141] It includes the study and application of psychology for the purpose of understanding, preventing, and relieving psychologically based distress, dysfunction or mental illness and to promote subjective well-being and personal development. Central to its practice are psychological assessment and psychotherapy although clinical psychologists may also engage in research, teaching, consultation, forensic testimony, and program development and administration.[142]

Credit for the first psychology clinic in the United States typically goes to Lightner Witmer, who established his practice in Philadelphia in 1896. Another modern psychotherapist was Morton Prince.[141] For the most part, in the first part of the twentieth century, most mental health care in the United States was performed by specialized medical doctors called psychiatrists. Psychology entered the field with its refinements of mental testing, which promised to improve diagnosis of mental problems. For their part, some psychiatrists became interested in using psychoanalysis and other forms of psychodynamic psychotherapy to understand and treat the mentally ill.[34] In this type of treatment, a specially trained therapist develops a close relationship with the patient, who discusses wishes, dreams, social relationships, and other aspects of mental life. The therapist seeks to uncover repressed material and to understand why the patient creates defenses against certain thoughts and feelings. An important aspect of the therapeutic relationship is transference, in which deep unconscious feelings in a patient reorient themselves and become manifest in relation to the therapist.[143]

Psychiatric psychotherapy blurred the distinction between psychiatry and psychology, and this trend continued with the rise of community mental health facilities and behavioral therapy, a thoroughly non-psychodynamic model which used behaviorist learning theory to change the actions of patients. A key aspect of behavior therapy is empirical evaluation of the treatment's effectiveness. In the 1970s, cognitive-behavior therapy arose, using similar methods and now including the cognitive constructs which had gained popularity in theoretical psychology. A key practice in behavioral and cognitive-behavioral therapy is exposing patients to things they fear, based on the premise that their responses (fear, panic, anxiety) can be deconditioned.[144]

Mental health care today involves psychologists and social workers in increasing numbers. In 1977, National Institute of Mental Health director Bertram Brown described this shift as a source of "intense competition and role confusion".[34] Graduate programs issuing doctorates in psychology (PsyD) emerged in the 1950s and underwent rapid increase through the 1980s. This degree is intended to train practitioners who might conduct scientific research.[59]

Some clinical psychologists may focus on the clinical management of patients with brain injurythis area is known as clinical neuropsychology. In many countries, clinical psychology is a regulated mental health profession. The emerging field of disaster psychology (see crisis intervention) involves professionals who respond to large-scale traumatic events.[145]

The work performed by clinical psychologists tends to be influenced by various therapeutic approaches, all of which involve a formal relationship between professional and client (usually an individual, couple, family, or small group). Typically, these approaches encourage new ways of thinking, feeling, or behaving. Four major theoretical perspectives are psychodynamic, cognitive behavioral, existentialhumanistic, and systems or family therapy. There has been a growing movement to integrate the various therapeutic approaches, especially with an increased understanding of issues regarding culture, gender, spirituality, and sexual orientation. With the advent of more robust research findings regarding psychotherapy, there is evidence that most of the major therapies have equal effectiveness, with the key common element being a strong therapeutic alliance.[146][147] Because of this, more training programs and psychologists are now adopting an eclectic therapeutic orientation.[148][149][150][151][152]

Diagnosis in clinical psychology usually follows the Diagnostic and Statistical Manual of Mental Disorders (DSM), a handbook first published by the American Psychiatric Association in 1952. New editions over time have increased in size and focused more on medical language.[153] The study of mental illnesses is called abnormal psychology.

Educational psychology is the study of how humans learn in educational settings, the effectiveness of educational interventions, the psychology of teaching, and the social psychology of schools as organizations. The work of child psychologists such as Lev Vygotsky, Jean Piaget, Bernard Luskin, and Jerome Bruner has been influential in creating teaching methods and educational practices. Educational psychology is often included in teacher education programs in places such as North America, Australia, and New Zealand.

School psychology combines principles from educational psychology and clinical psychology to understand and treat students with learning disabilities; to foster the intellectual growth of gifted students; to facilitate prosocial behaviors in adolescents; and otherwise to promote safe, supportive, and effective learning environments. School psychologists are trained in educational and behavioral assessment, intervention, prevention, and consultation, and many have extensive training in research.[154]

Industrialists soon brought the nascent field of psychology to bear on the study of scientific management techniques for improving workplace efficiency. This field was at first called economic psychology or business psychology; later, industrial psychology, employment psychology, or psychotechnology.[155] An important early study examined workers at Western Electric's Hawthorne plant in Cicero, Illinois from 19241932. With funding from the Laura Spelman Rockefeller Fund and guidance from Australian psychologist Elton Mayo, Western Electric experimented on thousands of factory workers to assess their responses to illumination, breaks, food, and wages. The researchers came to focus on workers' responses to observation itself, and the term Hawthorne effect is now used to describe the fact that people work harder when they think they're being watched.[156]

The name industrial and organizational psychology (IO) arose in the 1960s and became enshrined as the Society for Industrial and Organizational Psychology, Division 14 of the American Psychological Association, in 1973.[155] The goal is to optimize human potential in the workplace. Personnel psychology, a subfield of IO psychology, applies the methods and principles of psychology in selecting and evaluating workers. IO psychology's other subfield, organizational psychology, examines the effects of work environments and management styles on worker motivation, job satisfaction, and productivity.[157] The majority of IO psychologists work outside of academia, for private and public organizations and as consultants.[155] A psychology consultant working in business today might expect to provide executives with information and ideas about their industry, their target markets, and the organization of their company.[158]

One role for psychologists in the military is to evaluate and counsel soldiers and other personnel. In the U.S., this function began during World War I, when Robert Yerkes established the School of Military Psychology at Fort Oglethorpe in Georgia, to provide psychological training for military staff military.[34][159] Today, U.S Army psychology includes psychological screening, clinical psychotherapy, suicide prevention, and treatment for post-traumatic stress, as well as other aspects of health and workplace psychology such as smoking cessation.[160]

Psychologists may also work on a diverse set of campaigns known broadly as psychological warfare. Psychologically warfare chiefly involves the use of propaganda to influence enemy soldiers and civilians. In the case of so-called black propaganda the propaganda is designed to seem like it originates from a different source.[161] The CIA's MKULTRA program involved more individualized efforts at mind control, involving techniques such as hypnosis, torture, and covert involuntary administration of LSD.[162] The U.S. military used the name Psychological Operations (PSYOP) until 2010, when these were reclassified as Military Information Support Operations (MISO), part of Information Operations (IO).[163] Psychologists are sometimes involved in assisting the interrogation and torture of suspects, though this has sometimes been denied by those involved and sometimes opposed by others.[164]

Medical facilities increasingly employ psychologists to perform various roles. A prominent aspect of health psychology is the psychoeducation of patients: instructing them in how to follow a medical regimen. Health psychologists can also educate doctors and conduct research on patient compliance.[165]

Psychologists in the field of public health use a wide variety of interventions to influence human behavior. These range from public relations campaigns and outreach to governmental laws and policies. Psychologists study the composite influence of all these different tools in an effort to influence whole populations of people.[166]

Black American psychologists Kenneth and Mamie Clark studied the psychological impact of segregation and testified with their findings in the desegregation case Brown v. Board of Education (1954).[167]

Positive psychology is the study of factors which contribute to human happiness and well-being, focusing more on people who are currently health. In 2010 Clinical Psychological Review published a special issue devoted to positive psychological interventions, such as gratitude journaling and the physical expression of gratitude. Positive psychological interventions have been limited in scope, but their effects are thought to be superior to that of placebos, especially with regard to helping people with body image problems.

Quantitative psychological research lends itself to the statistical testing of hypotheses. Although the field makes abundant use of randomized and controlled experiments in laboratory settings, such research can only assess a limited range of short-term phenomena. Thus, psychologists also rely on creative statistical methods to glean knowledge from clinical trials and population data.[168] These include the Pearson productmoment correlation coefficient, the analysis of variance, multiple linear regression, logistic regression, structural equation modeling, and hierarchical linear modeling. The measurement and operationalization of important constructs is an essential part of these research designs.

A true experiment with random allocation of subjects to conditions allows researchers to make strong inferences about causal relationships. In an experiment, the researcher alters parameters of influence, called independent variables, and measures resulting changes of interest, called dependent variables. Prototypical experimental research is conducted in a laboratory with a carefully controlled environment.

Repeated-measures experiments are those which take place through intervention on multiple occasions. In research on the effectiveness of psychotherapy, experimenters often compare a given treatment with placebo treatments, or compare different treatments against each other. Treatment type is the independent variable. The dependent variables are outcomes, ideally assessed in several ways by different professionals.[171] Using crossover design, researchers can further increase the strength of their results by testing both of two treatments on two groups of subjects.

Quasi-experimental design refers especially to situations precluding random assignment to different conditions. Researchers can use common sense to consider how much the nonrandom assignment threatens the study's validity.[172] For example, in research on the best way to affect reading achievement in the first three grades of school, school administrators may not permit educational psychologists to randomly assign children to phonics and whole language classrooms, in which case the psychologists must work with preexisting classroom assignments. Psychologists will compare the achievement of children attending phonics and whole language classes.

Experimental researchers typically use a statistical hypothesis testing model which involves making predictions before conducting the experiment, then assessing how well the data supports the predictions. (These predictions may originate from a more abstract scientific hypothesis about how the phenomenon under study actually works.) Analysis of variance (ANOVA) statistical techniques are used to distinguish unique results of the experiment from the null hypothesis that variations result from random fluctuations in data. In psychology, the widely usd standard ascribes statistical significance to results which have less than 5% probability of being explained by random variation.[173]

Statistical surveys are used in psychology for measuring attitudes and traits, monitoring changes in mood, checking the validity of experimental manipulations, and for other psychological topics. Most commonly, psychologists use paper-and-pencil surveys. However, surveys are also conducted over the phone or through e-mail. Web-based surveys are increasingly used to conveniently reach many subjects.

Neuropsychological tests, such as the Wechsler scales and Wisconsin Card Sorting Test, are mostly questionnaires or simple tasks used which assess a specific type of mental function in the respondent. These can be used in experiments, as in the case of lesion experiments evaluating the results of damage to a specific part of the brain.[174]

Observational studies analyze uncontrolled data in search of correlations; multivariate statistics are typically used to interpret the more complex situation. Cross-sectional observational studies use data from a single point in time, whereas longitudinal studies are used to study trends across the life span. Longitudinal studies track the same people, and therefore detect more individual, rather than cultural, differences. However, they suffer from lack of controls and from confounding factors such as selective attrition (the bias introduced when a certain type of subject disproportionately leaves a study).

Exploratory data analysis refers to a variety of practices which researchers can use to visualize and analyze existing sets of data. In Peirce's three modes of inference, exploratory data anlysis corresponds to abduction, or hypothesis formation.[175]Meta-analysis is the technique of integrating the results from multiple studies and interpreting the statistical properties of the pooled dataset.[176]

A classic and popular tool used to relate mental and neural activity is the electroencephalogram (EEG), a technique using amplified electrodes on a person's scalp to measure voltage changes in different parts of the brain. Hans Berger, the first researcher to use EEG on an unopened skull, quickly found that brains exhibit signature "brain waves": electric oscillations which correspond to different states of consciousness. Researchers subsequently refined statistical methods for synthesizing the electrode data, and identified unique brain wave patterns such as the delta wave observed during non-REM sleep.[177]

Newer functional neuroimaging techniques include functional magnetic resonance imaging and positron emission tomography, both of which track the flow of blood through the brain. These technologies provide more localized information about activity in the brain and create representations of the brain with widespread appeal. They also provide insight which avoids the classic problems of subjective self-reporting. It remains challenging to draw hard conclusions about where in the brain specific thoughts originateor even how usefully such localization corresponds with reality. However, neuroimaging has delivered unmistakable results showing the existence of correlations between mind and brain. Some of these draw on a systemic neural network model rather than a localized function model.[178][179][180]

Psychiatric interventions such as transcranial magnetic stimulation and of course drugs also provide information about brainmind interactions. Psychopharmacology is the study of drug-induced mental effects.

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Psychology - Wikipedia, the free encyclopedia

Neuroscience – Cabell Huntington Hospital – Huntington, WV

For more information, please call 304.691.1787

The neuroscience staffincludes many experienced and respectedphysicians who bring unique skills, experience and training to this world-class referral center for the Tri-State area.They havetreated patients from across the United States, as well as throughout the region. The Advanced Primary Stroke Center has earned The Joint Commission's Gold Seal of Approval by demonstrating compliance with The Joint Commission's national standards for healthcare quality and safety in disease-specific care. And thanks to the leadership of these skilled specialists, Cabell Huntington Hospital has been named a Blue Distinction Center for Spine Surgery by Highmark Blue Cross Blue Shield West Virginia and earned a Top 10% in the Nation Quality Rating for Spinal Surgery from Carechex, a medical quality rating service.

Neurology services and neurophysiology testing are available for both adults and children. Our specialists diagnose, evaluate and provide treatment for epilepsy, headache, movement disorders, multiple sclerosis, stroke and neuromuscular diseases. Neurosurgery services are available for both adults and children, including surgery for brain tumors, movement disorders, epilepsy, trigeminal neuralgia and other conditions affecting the brain, spine, spinal cord, pituitary gland and/or neurovascular system.

Dr. Tony Alberico, a board-certified neurosurgeon,offers a breadth of neurosurgical experience that rivals any in the region. He has quickly established himself as an excellent surgeon with outstanding judgment. He serves as the chairman of the Department of Neuroscience at the Joan C. Edwards School of Medicine and as the director of the Back and Spine Center. Dr. Alberico is experienced in the management of spinal disorders andin developing advances in spine care.

Dr. Paul Fergusonis a board-certified neurologist who specializes in diagnosing and treating headaches, including chronic migraines. He is experienced in managing the complexities of multiple sclerosis and providing patients with the most advanced medical treatments, neuroimaging and physical therapy. Dr. Ferguson earned his medical degree at the MU Joan C. Edwards School of Medicine and completed his residency in neurology at Wake Forest University Baptist Medical Center.

Dr. Samrina Hanif is a fellowship-trained neurologist who specializes in the diagnosis and treatment of epilepsy. Dr. Hanif earned her medical degree at Dow Medical University in Karachi, Pakistan, and she completed her residency at New York Medical College in Manhattan. Her fellowship training in epilepsy/clinical neurophysiology was completed at Vanderbilt University. Her special interests include refractory epilepsy and treating children with autism and epilepsy.

Dr. Alastair T. Hoyt, a fellowship-trained physician specializing in neurosurgery, offers diagnosis and treatment of disorders or injuries to the brain, spinal cord and/or peripheral nerves. After graduating from medical school at the University of Nebraska, Dr. Hoyt completed his residency in neurosurgery at the Medical College of Wisconsin and a fellowship at the Barrow Neurological Institute, along with additional training in Gamma Knife radiosurgery.

Dr. Paul Knowles is certified by the American Board of Pediatrics and the American Board of Psychiatry and Neurology. He completed fellowship training in pediatric neurology at Baylor University College of Medicine in Houston, Texas, and a pediatric residency at Childrens Hospital Medical Center in Akron, Ohio. He earned his medical degree at Eastern Virginia Medical School in Norfolk, Virginia. Dr. Knowles has more than 30 years of experience in pediatric neurology.

Dominika Lozowska, MD, a fellowship-trained physician specializing in neurology, offers diagnosis and treatment of disorders of the central and peripheral nervous system, such as epilepsy, Parkinsons disease and muscular sclerosis. She completed her residency in neurology at Fletcher Allen Health Center. She then completed a fellowship in neurophysiology at the University of South Florida and a neuromuscular fellowship at the University of Colorado School of Medicine.

Dr. Rida Mazagri's extensive training and experience includes a fellowship in Clinical Stroke Research at the University of Saskatchewan and a fellowship in Pediatric Neurosurgery at the University of Ottawa/Childrens Hospital of Eastern Ontario. He earned his medical degree at Al-Fateh University Medical School in Tripoli, Libya, and he is board certifed in neurological surgery. Dr. Mazagritreats adult and pediatric patients.

Paul Muizelaar, MD, PhD, an experienced, fellowship-trained neurosurgeon, has an extensive career in neurosurgery and is affiliated with the Back and Spine Center at CHH. He is certified by the Royal Dutch Board of Medical Specialties in Neurological Surgery. He earned his medical degree and doctorate at the University of Amsterdam School of Medicine, and he completed fellowship training in neurosurgery at the Medical College of Virginia.

Dr. Justin Nolte is a neurologist who specializes in stroke care and oversees Cabell Huntington Hospital's Advanced Primary Stroke Center, which has earned The Joint Commission's Gold Seal of Approval. Dr. Nolte earned his medical degree from the Marshall University Joan C. Edwards School of Medicine and completed a residency in neurology at the Medical University of South Carolina.

Dr. Mitzi Payne completed a fellowship in pediatric neurology and offers a variety of services unique to the region, including Botox injections for children suffering from spasticity caused by cerebral palsy and other disorders. She also manages intrathecal pumps implanted for severe spasticity. She manages pediatric epilepsy, including interpreting EEGs, pediatric headache disorders and other neurologic conditions unique to children.

Dr. Sona Shah is the director of CHH's Epilepsy Center, the region's first center to provide care for patients with epilepsy and other seizure disorders. Dr. Shah completed her neurology residency at SUNY Downstate Medical Center in Brooklyn, NY, as well as fellowships in neurophysiology and epilepsy at the University of Chicago. She is board certified in neurology, clinical neurophysiology, epilepsy monitoring and neuromuscular medicine.

Collectively, the members of theneuroscience staff have published hundreds of peer-reviewed scientific articles, book chapters and abstracts. They have lectured extensively nationally and internationally and have received multiple patents for medical breakthroughs. Although recognized for their academic achievements, their clinical experience and training is unparalleled in the region.

For more information or to schedule an appointment with a member of the Marshall University Department of Neuroscience, please call 304.691.1787.

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Neuroscience - Cabell Huntington Hospital - Huntington, WV

Neuroscience Program – University of Illinois

Welcome to the NSP at Illinois Welcome to the Neuroscience Program (NSP) at the University of Illinois at Urbana-Champaign. The NSP is an interdisciplinary program of study and research leading to the doctoral degree. We offer a rigorous yet flexible program designed to foster the growth of the student through research activities, close interactions with the faculty, and exposure to top neuroscientists through our seminar series and attendance at professional meetings.

Recognizing that there are many paths to success in neuroscience, the program imposes few specific requirements. Students design their own programs leading to the Ph.D., with oversight by faculty committees ensuring appropriate depth and breadth of training.

The NSP currently has over 85 affiliated faculty from more than 20 departments, and 70 students, studying the brain from a broad range of perspectives. We invite you to learn more about our program, research, and people.

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Neuroscience Program - University of Illinois