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Biologists confirm genetics of first ShareLunker Offspring Entered into Program – Weatherford Democrat

ATHENS In March 2006, angler Edward Reid pulled a staggering 14.48-pound largemouth bass from the depths of Lake Conroe near Houston.

On Feb. 10, nearly 11 years later and more than 234 miles away, angler Ryder Wicker caught the 13.07-pound offspring of that fish from Marine Creek Lake near Fort Worth.

The Lake Conroe fish, later called ShareLunker 410, was able to leave a legacy of her big-bass genetics to the state thanks to the Texas Parks and Wildlife Departments Toyota ShareLunker Program, which has been selectively breeding and stocking angler-caught largemouth bass over 13 pounds since 1986 with the goal of increasing the production of trophy-sized fish in Texas reservoirs.

After Reid donated ShareLunker 410 to the program in 2006, TPWD Inland Fisheries biologists took her to the lunkerbunker at the Texas Freshwater Fisheries Center (TFFC) in Athens to pair up with a male ShareLunker offspring.

That pairing of pure Florida largemouth bass produced thousands of fingerlings that were stocked in Marine Creek Lake and other public Texas reservoirs a few months later, one of which grew into the 13.07 pounder Ryder caught last week: ShareLunker 566.

The genetic link was confirmed Feb. 17, just days after TFFC staff transported a fin clip to the A.E. Wood Hatchery in San Marcos.

The tests confirmed what biologists already suspected based on the results of scanning a tag near the fishs head this was a daughter produced by ShareLunker 410 and a male fish with a more esoteric name, 0LB-0504.

The catch of ShareLunker 566 from Marine Creek Lake not only validates the goal of TPWDs selective breeding program of producing ShareLunker-size bass, but also demonstrates how anglers can help others by donating their ShareLunkers to TPWD for breeding purposes, said ShareLunker Program Coordinator Kyle Brookshear. Mr. Wicker can tip his hat to Mr. Reid for making this moment possible.

ShareLunker 566 was among the tagged fingerlings stocked in Marine Creek Lake 11 years ago for a ShareLunker evaluation research project. Researchers wanted to compare growth of ShareLunker fingerlings to growth of the resident bass population in several Texas lakes.

Researchers on the ShareLunker evaluation project found that over a four year period of time, compared to wild fish of the same age (four years old) and gender (female), ShareLunker offspring weighed more by a half pound on average.

Now those same TPWD biologists are in the process of comparing ShareLunker offspring with regular Florida largemouth bass and the initial results are showing even more significant size differences between the fish.

Mukhtar Farooqi, a TPWD Inland Fisheries biologist, said results from the study could be used as a basis to incorporate ShareLunker offspring into the Florida largemouth bass broodfish in hatcheries across the state.

That would increase the total ShareLunker offspring stocked annually into participating lakes from tens of thousands to more than eight million.

Farooqi also said if ShareLunker 566 is able to spawn, the second generation offspring may have a better chance of obtaining a higher weight due to the concentration of those genes.

We know this fish is a big fish produced by a big fish coming from the selective breeding program, so there is a bit of a lineage, Farooqi said. Thats what you would want to maintain; its the best scenario when youre dealing with known genetics.

ShareLunker 566 is the first 13 pound or larger Florida largemouth bass submitted to the Toyota ShareLunker program so far this season, but anglers have until March 31 to submit their catch for TPWD to collect as brood stock for spawning.

Anglers can enter 13 pound or heavier bass into the program for certified weight, DNA sample and immediate release through April 30.

Lake Conroe, the fishery that produced ShareLunker 410 and 16 other ShareLunkers, is hosting the Bassmaster Classic tournament March 24-26, which could yield another addition to the program.

The Toyota ShareLunker Program is made possible by a grant to the Texas Parks & Wildlife Foundation from Gulf States Toyota.

Toyota is a longtime supporter of the Foundation and Texas Parks and Wildlife Department, providing major funding for a wide variety of education, fish, parks and wildlife projects.

For updates on the ShareLunker program and to view photos of ShareLunker 566, visit http://www.facebook.com/ShareLunkerprogram/.

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Biologists confirm genetics of first ShareLunker Offspring Entered into Program - Weatherford Democrat

Art Made with Human DNA Explores the Future of Genetics in Birmingham – Labiotech.eu (blog)

Gene Craft: Art in the Biogenetic Ageopened this week at Birmingham Open Media (BOM) in the UK. Aiming to explore thesocial, economic and emotional implications of the most recent breakthroughs in genetics, the exhibition features two living art piecescreated with human DNAby bioartists Laurie Ramsell and Gina Czarnecki.

After theHuman Fertilisation and Embryology Authority (HFEA) approvedthe technology to create three-parent babies in the UK last December, many have started to question the broader implications of genetic technologies. The Gene Craft exhibition elaborates on this concept by presenting living artwork that makes visitors imagine a future of bioengineered beings built and controlled by humans.

The first piece is by British artist Laurie Ramsell,who explores the genetic relationship between humans and model organisms. One of them is the zebrafish, which is routinely used in research to understand basic molecular processes that can then be extrapolated to human biology.

Laurie Ramsells Homdanio Birminghamensis

Homdanio Birminghamensisis a sculpture taking the shape of a zebrafish embryo made from bacterial cellulose and the artists own DNA. The piecewas created in collaboration with professor and bioartist Simon Park. As part of the 100,000 Genomes Project, it is intended to raise public awareness about research into the human genome being pioneered at the University of Birmingham.

The second piece featured in the Gene Craft exhibition is Gina Czarneckis Heirloom, a living portrait of the artists daughters. Skin cells from the girls are cultured and grown onto glass casts of their faces, creating paper-thin portraits with their own DNA.

Gina Czarneckis Heirloom

Heirloom invites visitors to imagine a future where our own cells are grown on demand for medical applications. But, at the same time, it intends to highlight the ethical implicationsof these procedures regarding the ownership of our own biological materials.

Gene Craft: Art in the Biogenetic Age will be open until May 13 in Birmingham. During that time, the BOM gallery will host a series of talks and workshops to bring together artists and scientists and discuss the issues raised by the bioart pieces exhibited.

Images via BOM and Gina Czarnecki

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Art Made with Human DNA Explores the Future of Genetics in Birmingham - Labiotech.eu (blog)

Cutting Edge Science Literally – Seton Hall University News & Events

Wednesday, February 22, 2017

By Michael Ricciardelli, Christine Aromando

In Seton Hall's Department of Biochemistry, undergraduate students work in the lab alongside graduate students, Ph.D. candidates and professors on some of the leading biochemical and medical questions of the day. Lab 419 was custom built by Professors David Sabatino and Monika Raj to facilitate biomedical research, and the results to date have been groundbreaking.

With their most recent work published in a number of prestigious biochemistry journals, Professor Raj and her team of student researchers focus on developing new biochemical methodologies for the rapid sequencing, or "mapping," of proteins and their building blocks, peptides.

In sequencing or "mapping" these peptides and proteins in a sense the building blocks of life scientists can better see, identify, diagnose and fix malfunctions that can lead to disease.

To that end, the Raj research group works at synthesizing peptides and proteins to ultimately block disease states including cancer, Parkinson's and age-related maladies such as Alzheimer's.

Professor Raj was named Seton Hall Faculty Researcher of the Year in 2016. Notably, her article, "Site-Selective Chemical Cleavage of Peptide Bonds," authored along with Ph.D. student Hader Elashal and published in The Royal Society of Chemistry's Chemical Communications, was named "F1000 Prime recommended," which means that a global Faculty of the world's leading scientists and clinicians selected and honored this research as "important" work.

Chemical Cleavage

At its most basic level, life is comprised of amino acids and the proteins they help to form. Amino acids are bonded together to form peptides, and strings of bonded peptides form proteins. On some level, life itself can be described as a series of protein to protein interactions. In fact, most diseases can be linked to proteins within the body and the brain interacting badly, with one protein being the "instigator" so to speak.

Much like a mother separating two unwieldy children, as the study of disease and its cures advances, modern molecular and medical research has put much of its emphasis on separating these proteins behaving badly. Unlike parenthood, however, the ultimate goal in medical research is to isolate the instigator and kill it.

But to kill a bad acting protein, one must know itand that's where the work of Professor Raj and her students comes in. They have found a way to chemically cleave or break the offending proteins apart in a way that gives researchers a clear view of the transgressor, allowing them to sequence, or "map," the diseased or mutated proteins. Previous cutting methods, although good for healthy proteins, were not compatible with the cutting of these diseased or mutated ones.

The cutting or cleavage process developed by Professor Raj's team allows researchers to clearly see and map the constituent parts of malfunctioning proteins as well as, importantly, isolating them. This allows researchers the ability to devise remedies including synthesizing unique peptides and proteins to essentially eliminate the diseased or mutated ones that are specific for these affected molecules without adversely affecting other healthy molecules in near proximity.

Revolutionizing Protein Synthesis: Faster, Better, More

If most of life itself can be seen as a series of protein to protein interactions (it can), then a laboratory that specializes in examining and attempting to repair life on a molecular level is going to have to synthesize a great many peptides and proteins.

The Raj group has revolutionized protein synthesis. In laboratories all across the world, scientists synthesize peptides and then group these peptides together to formulate proteins. At present, it is a cumbersome and tedious process, with many steps burdened by the necessary addition of many extraneous substances; it is largely governed by the limitations of the current state of lab machinery which allows for the combination of only 50 amino acids at a time to create peptides. Proteins often contain 100,000 amino acids. The process can take days.

Through their discovery of a totally chemical process for synthesizing protein, Professor Raj and her team of students have cut that time down to hours, excised many of the input substances from the process (thus extremely limiting a number of extraneous byproducts in the results) and increased the yield of protein by double-digit multiples. In short, they have found a way to synthesize proteins chemically in significantly less time with greater purity and a far greater yield: Faster, better, more.

What does all of this mean for the general public? The ability to clearly observe mutated proteins and then synthesize new ones more efficiently and in less time will ultimately pave the way for pinpoint accuracy in disease eradication. This level of accuracy can be readily appreciated by anyone who has experienced the ravages of chemotherapy and other disease treatments that are necessarily widespread in their application.

The revolutionary research on protein synthesis, published for 2017 as an Advance Article in The Royal Society of Chemistry's high-impact journal, Chemical Science, is entitled "Serine promoted synthesis of peptide thioester-precursor on solid support for native chemical ligation." Professor Raj authored the work along with graduate students Hader Elashal and Yonnette Sim.

Additional research and publications from the Raj Group for 2016

Organic Letters, "Glutamic Acid Selective Chemical Cleavage of Peptide Bonds," authored by Professor Raj along with Ph.D. student Neelam Lahankar and undergraduate students Lyssa Buiserreth and Joseph Nalbone '16.

Chemical Communications, "Fmoc solid-phase synthesis of C-terminal modified peptides by formation of a backbone cyclic urethane moiety" authored by Professor Raj along with Ph.D. students Hader Elashal and Ryan Cohen.

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Cutting Edge Science Literally - Seton Hall University News & Events

The Anatomy of Populist Economics – Project Syndicate

PARIS For at least the past year, populism has been wreaking havoc on Western democracies. Populist forces parties, leaders, and ideas underpinned the Leave campaigns victory in the United Kingdoms Brexit referendum and Donald Trumps election as President of the United States. Now, populism lurks ominously in the background of the Netherlands general election in March and the French presidential election in April and May.

But, despite populisms seeming ubiquity, it is a hard concept to pin down. Populists are often intolerant of outsiders and those who are different; and yet Geert Wilders, the far-right Dutch populist leader, is a firm believer in gay rights. In the US, Trumps presidential campaign was described as an anti-elite movement; and yet his administration is already practically a subsidiary of Goldman Sachs.

While todays populist resurgence comes from the nationalist right, some of the leading populist exponents in recent decades such as Venezuelas late president, Hugo Chvez were firmly on the left. What they share is a zero-sum view of the world, which necessitates the creation of scapegoats who can be blamed for all problems. Moreover, because populist leaders claim to embody the uniform will of a mythical people, they consider democracy to be a means to power, rather than a desirable end in itself.

But populists have more in common than an obsession with cultural boundaries and political borders. They also share a recipe for economic governance, one that Project Syndicate commentators have been tracking since long before todays brand of populism began dominating the worlds headlines. Guided by their insights, we can begin to understand the origins of todays populist resurgence, and what is in store for Western countries where its avatars come to power.

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The Anatomy of Populist Economics - Project Syndicate

Students show passion for neuroscience at Brain Bee – BurlingtonFreePress.com

Free Press Staff Published 2:26 p.m. ET Feb. 23, 2017 | Updated 24 hours ago

Top Brain Bee wilnners from left: Ryan Martin, third place, senior, Burlington Tech Center; Qingxi (Tim) Jia, second place, senior, South Burlington High School; Aidan May, first place, junior, Mount Abraham Union; Lisa Bernardin, Vermont Brain Bee coordinator.(Photo: Jennifer Nachbur, Larner College of Medicine director of public relations)

A three-pound human super computer was the focus of the Vermont Brain Bee, held Feb. 18 at the Larner College of Medicine at the University of Vermont. The event attracted 40 students from 10 high schools across the state a record in the Vermont Brain Bees eight-year history who eagerly participated in written and wet lab examinations, and a first and final oral bee round centered on the many complex details of the brain and nervous system.

Mount Abraham Union High School junior Aidan May was declared the first-place winner, with South Burlington High School senior Qingxi Tim Jia coming in second place and Ryan Martin, a senior at Burlington Technical Center, the third-place winner. The school team that earned first place was Mount Abraham, whose members include: Aidan May, Kameryn Norse, Delana Tow, Isabel Lucarelli. The Middlebury Union High School team earned second-place. Team members were Isabel Rosenburg, Riley Fenster, Grace Widelitz and Erin Stocker.

The top eight participants are holding up their answers to one of 10 questions at the Brain Bee.(Photo: Jennifer Nachbur, Larner College of Medicine director of public relations)

Schools represented at the Bee included Burlington Technical Center, Bellows Falls Union High School, Champlain Valley Union High School, Essex High School, Middlebury Union High School, Mount Abraham Union High School, Otter Valley Union High School, Rice Memorial High School, South Burlington High School and Stowe High School.

After the preliminary competition agenda was complete, students were treated to three neurological disorder vignettes performed by pediatric neuropsychologists Sharon Leachof the Stern Center for Language and Learning, and Kathryn Workman of the Vermont Department of Health. Brain Bee participants were able to observe and guess diagnoses, as well as ask for additional diagnostic information. The students showed a lot of enthusiasm, as they asked well thought out questions, said Leach.

Students answer 28 name and function questions from drawings and preserved brains.(Photo: Jennifer Nachbur, Larner College of Medicine director of public relations)

Following the first oral round, participants heard a keynote presentation on auditory neuroscience from Vermont Brain Bee alumnus and Champlain Valley Union High School graduate Kameron Clayton, who is currently a doctoral student at Harvard University in the Program in Speech & Hearing Bioscience & Technology.

Anthony Morielli, associate professor of pharmacology and director of the Neuroscience Graduate Program, and Sean Flynn, assistant professor of neurological sciences at the UVM Larner College of Medicine, served as judges at the event.

University of Vermont Neuroscience Graduate Program students helped with the event. They were all impressed with the level of knowledge the high school students displayed during the written and practical quizzes. I know a lot of neuroanatomy now, said Patrick Mullen, a second-year doctoral student, at the UVM Larner College of Medicine. If I had had a three- or four-year jumpstart like this wow!

Riley St. Clair, a fourth-year Ph.D. student organized and ran the practical exam, which featured identification on brain specimens, and helped run the preparatory Brain Bee Boot Camp held two weeks before the competition. Its really cool that high school students are getting exposed to neuroscience so early, she said.

Winning Brain Bee team was from Mount Abraham Union High School. From left: Aidan May, Kameryn Norse, Delana Tow, Isabel Lucarelli and teacher Samantha Kayhart.(Photo: Jennifer Nachbur, Larner College of Medicine director of public relations)

Vermont Brain Bee Coordinator Lisa Bernardin is pleased that more and more high school students are learning about neuroscience. Its so important that this age-group learns about the brain - its what controls everything we do, she said. Gaining access to the faculty, students and facilities at the UVM Larner College of Medicine is a wonderful opportunity for these students who will soon be making college and career decisions.

As the winner of the 2017 Vermont Brain Bee, Aidan May is eligible to participate in the National Brain Bee held in Baltimore from March 17 to 19.

A number of Vermont-based businesses and organizations help support the Vermont Brain Bee each year. For more information, visit vermontbrainbee.com.

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Students show passion for neuroscience at Brain Bee - BurlingtonFreePress.com

CNU Board of Visitors approves new neuroscience degree, faculty salary change – Daily Press

NEWPORT NEWS Students interested in neuroscience will soon have a formal option to study the discipline at Christopher Newport University.

A bachelor of science degree in neuroscience was given approval to be added to the university's undergraduate catalog by CNU's Board of Visitors at its meeting Friday afternoon. The degree will include courses in neuroscience, chemistry, physics, mathematics and biology.

Neuroscience is the scientific study of the nervous system, how its develops and its functions.

CNU currently offers majors in chemistry, biochemistry and cellular, molecular and physiological biology within its molecular biology and chemistry department. Students can also major in chemistry or biology.

Since 2011, students have been able to major in neuroscience as an interdisciplinary program, an individualized program of study. Provost David C. Doughty Jr. said the program has about 30 students interested each year.

The recognition as a formal degree will enhance students' abilities to receive scholarships that are designated for studies in STEM science, technology, engineering and mathematics.

"It's an important step for us," Doughty said. "It won't dramatically change our lives of our students. Our students are hugely successful. That's sort of been the brunt of our pitch to (the State Council of Higher Education for Virginia). We've had a successful program. Students go on to medical school, to graduate school in neuroscience, they go out to have great careers. None of that's really going to change. It's just a status question in some sense in making sure that they are recognized as being the STEM students that they are."

The next step in officially offering the degree is approval of the program by the State Council of Higher Education for Virginia, which Doughty said should occur soon.

The board also approved next year's compensation plan for instructional faculty. The plan is the same as the current academic year's except for one change professors and distinguished professors can now make a maximum of $178,000, a $5,000 increase from the current plan's maximum.

Hammond can be reached by phone at 757-247-4951.

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CNU Board of Visitors approves new neuroscience degree, faculty salary change - Daily Press

Conflicts of Interest: Are Humans Inherently Selfish? – Live Science

President Donald Trump signed an executive order withdrawing the U.S. from the Trans-Pacific Partnership on Jan. 23, 2017.

President Donald Trump has been dogged by questions about conflicts of interest. He has declined to divest himself of his assets or put them in a blind trust, as is customary for presidents, news reports say. He has tweeted in defense of his daughter's clothing line. And taxpayer money may go toward the Department of Defense leasing space in Trump Tower the president's property to remain close to the president when he is in Manhattan, CNN recently reported.

At the heart of any conflict-of-interest situation is the question of whether to act in your own best interest or do what is best for the greater good. Trump's issues might make a cynic shrug. After all, don't we all look out only for ourselves?

Psychological research suggests the opposite: that self-interest is far from people's primary motivation. In fact, humans are prone to act for the good of the group, many studies have found.

"In the past 20 years, we have discovered that people all around the world are a lot more moral and a lot less selfish than economists and evolutionary biologists had previously assumed, and that our moral commitments are surprisingly similar: to reciprocity, fairness and helping people in need, even if acting on these motives can be personally costly for a person," Samuel Bowles, an economist at the Santa Fe Institute and author of "The Moral Economy: Why Good Incentives Are No Substitute for Good Citizens" (Yale University Press, 2016), wrote in an email to Live Science. [No 'I' in Team: 5 Key Cooperation Findings]

Philosophers have been arguing about whether people are inherently selfish since there has been such a thing as philosophers. In Plato's "Republic," Socrates has a discussion with his older brother Glaucon in which Glaucon insists that people's good behavior actually only exists for self-interest: People only do the right thing because they fear being punished if they get caught. If human actions were invisible to others, Glaucon says, even the most "just" man would act purely for himself and not care if he harmed anyone in the process.

It's the sort of argument that might have appealed to Thomas Hobbes, the 17th-century English philosopher famous for saying that the natural state of man's life would be "nasty, brutish and short." According to Hobbes, humans must form social contracts and governments to prevent their selfish, violent tendencies from taking over.

Not all philosophers have agreed with this dour point of view, however. Philosopher John Locke, for example, thought that humans were inherently tolerant and reasonable, though he acknowledged humanity's capacity for selfishness.

So what does the science say? In fact, people are quite willing to act for the good of the group, even if it's against their own interests, studies show. But paradoxically, social structures that attempt to give people incentives for good behavior can actually make people more selfish.

Take a classic example: In 2000, a study in the Journal of Legal Studies found that trying to punish bad behavior with a fine backfired spectacularly. The study took place at 10 day care centers in Haifa, Israel. First, researchers observed the centers for four weeks, tracking how many parents arrived late to pick up their children, inconveniencing the day care staff. Next, six of the centers introduced a fine for parents who arrived more than 10 minutes late. The four other centers served as a control, for comparison. (The fine was small but not insignificant, similar to what a parent might have to pay a babysitter for an hour.)

After the introduction of the fine, the rate of late pickups didn't drop. Instead, it nearly doubled. By introducing an incentive structure, the day cares apparently turned the after-school hours into a commodity, the researchers wrote. Parents who might have felt vaguely guilty for imposing on teachers' patience before the fine now felt that a late pickup was just something they could buy. [Understanding the 10 Most Destructive Human Behaviors]

The Haifa day care study isn't the only one to find that trying to induce moral behavior with material incentives can make people less considerate of others. In a 2008 review in the journal Science, Bowles examined 41 studies of incentives and moral behavior. He found that, in most cases, incentives and punishments undermined moral behavior.

For example, in one study, published in 2000 in the journal World Development, researchers asked people in rural Colombia to play a game in which they had to decide how much firewood to take from a forest, with the consideration that deforestation would result in poor water quality. This game was analogous to real life for the people of the village. In some cases, people played the games in small groups but couldn't communicate about their decisions with players outside their group. In other cases, they could communicate. In a third condition, the players couldn't communicate but were given rules specifying how much firewood they could gather.

When allowed to communicate, the people in the small groups set aside self-interest and gathered less firewood for themselves, preserving water quality in the forest for the larger group as a whole. Regulations, on the other hand, had a perverse result over time: People gradually began to gather more and more firewood for themselves, risking a fine but ultimately putting their self-interest first.

"People look for situational cues of 'acceptable behavior,'" Bowles said. "Literally dozens of experiments show that if you offer someone a money incentive to perform a task (even one that she would have happily done without pay), this will 'turn on' the 'What's in it for me?' way of thinking, often to such an extent that the person will perform less with the incentive than without."

Though cooperation is ingrained in the human psyche to some extent, it's also obvious to anyone who has worked on a team that not everyone approaches group activities with the same attitude. An increasing focus on individual differences in humans reveals that some people tend to cooperate more than others.

"It has been known for quite a while that people differ quite a lot, and they differ in all kinds of behavioral tendencies," said F.J. Weissing, a theoretical biologist at the University of Groningen in the Netherlands. "But when people conducted experiments, they typically looked at the average behavior and not so much at the variation between subjects." [Top 10 Things that MakeHumansSpecial]

That variation among subjects turns out to be quite important. In 2015, Weissing and his colleagues published a paper in the journal PNAS in which they allowed people to play a game where they could choose to seek out either information about the choices of other players, or information about how successful those other players were. People were remarkably consistent about the kind of information they sought, the researchers found: Two-thirds always asked for the same kind of information, whether they preferred information about choices or success.

Then, the researchers split people into groups based on which information they preferred, with some groups comprising only people who liked choice information, some groups made up of only people who liked success information, and some mixed. These groups then played games in which cooperation benefited everyone, but a selfish strategy could elevate an individual's fortunes while hurting the group.

People who fixated on the success of their teammates were more likely to behave selfishly in these games, the researchers found. This finding shows that this strategy comparing others' successes and failures prompts people to engage in behaviors focused on their own gain, the researchers said.

In contrast, people who focus on how the rest of the group is acting, regardless of individual successes, might be more prone to working together, the researchers said.

Both cooperation and selfishness may be important behaviors, meaning that species may be most successful if they have some individuals that exhibit each behavior, Weissing told Live Science. In follow-up experiments that have not yet been published, he and his colleagues have found that in some economic games, mixed groups perform far better than groups made up only of conformists or only of those who look out for themselves. [7 Thoughts That Are Bad for You]

Very fundamental physiological differences between people may be at the root of these different social strategies, Weissing said, including differences in hormone levels and organization of the central nervous system. However, he agreed that situational factors can subtly push people toward cooperation or self-interest. More realistic studies of cooperative and selfish behavior are needed, he said.

"In real life, cooperation looks very, very different from these very, very simplified lab contexts," Weissing said. "And the dominant factor is not really money, but something else. I think that makes quite a difference."

Original article on Live Science.

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Conflicts of Interest: Are Humans Inherently Selfish? - Live Science

Dublin-based pig breeder joins genetics group Genus – Irish Times

about 10 hours ago Updated: about 8 hours ago

Dublin-based pig breeder Hermitage has entered into a strategic partnership with UK animal genetics group Genus. Under the deal, which is still subject to several closing conditions, Genuss PIC porcine unit will acquire the genetic rights and intellectual property of Hermitage.

The partnership will also see the Irish company become a strategic supply chain and distribution partner for PIC. PIC will acquire certain Hermitage customer relationships in Russia, the US and several European countries. The deal is expected to be finalised by the end of next month.

Established in 1958, Hermitage is one of the longest running porcine breeding and genetics companies in Europe, serving big producers in Europe and elsewhere. Its infrastructure includes nucleus farms and boar studs in Ireland and across Europe.

Commenting on the deal, Hermitage owner Ned Nolan said: This is an exciting step for Hermitage, as we join forces with a global pioneer in our field.

Our partnership with PIC will allow the continued use of the Hermitage gene pool to provide enhanced genetics to our global customer base, he added.

Genus chief executive Karim Bitar said: The partnership with Hermitage is an ideal fit with our porcine strategy.

It will provide Genus with the opportunity to accelerate genetic improvement by combining the PIC and Hermitage gene pools, he said.

In addition, Hermitages strong supply chain and customer-service oriented team will strengthen our ability to serve pig producers efficiently and reliably, he added.

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Dublin-based pig breeder joins genetics group Genus - Irish Times

Scientists generate a new plasmid-based reverse genetics system for rotaviruses – Phys.Org

February 24, 2017 Generation of recombinant rotavirus from cloned cDNA. Credit: Osaka University

Rotaviruses are the most common cause of severe diarrhea and kill hundreds of thousands of infants a year. Although current vaccines are effective in preventing aggravation of rotaviruses, the development of more effective vaccines at lower cost is expected. Technology cannot study well how rotaviruses invade and replicate in a cell. To identify which genes are crucial for the infection of rotaviruses, scientists at the Research Institute for Microbial Diseases at Osaka University report a new plasmid-based reverse genetics system. The study can be read in Proceedings of the National Academy of Sciences of the United States of America.

"Reverse genetics allows us to generate artificially engineered viruses", says Associate Professor Takeshi Kobayashi, who led the study. "Using reverse genetics, we can mutate a gene and see its effects on the virus," he added.

Reverse genetics systems have been developed for a wide number of viruses to study the conditions in which a virus thrives, but systems for multiple-segmented RNA-based viruses like rotaviruses have proven more difficult. Kobayashi's group solved this problem by including two viral proteins, FAST and VV capping enzyme, into their plasmid-based system. Taking advantage, the researchers tested their system by mutating a single protein of rotaviruses, NSP1, finding that they could decrease viral replication.

Through comprehensive testing of all proteins in future studies, Kobayashi expects to find the key determinants that make rotaviruses a severe pubic threat. "We could modify the propagation and pathogenicity of the rotavirus", he said.

Kobayashi is optimistic about how plasmid-based reverse genetics system will bring new innovations to combat rotaviruses. "Because no one could synthesize rotaviruses artificially, less is known about the replication and pathogenesis." He expects the system will increase the number of labs working on rotaviruses and lead to more effective vaccines.

Explore further: Researchers find chink in the armor of viral 'tummy bug'

More information: Yuta Kanai et al. Entirely plasmid-based reverse genetics system for rotaviruses, Proceedings of the National Academy of Sciences (2017). DOI: 10.1073/pnas.1618424114

Researchers at Griffith University's Institute for Glycomics in collaboration with colleagues at the University of Melbourne have moved a step closer to identifying a broad spectrum treatment for the dreaded 'viral tummy ...

Researchers from Griffith University's Institute for Glycomics and the University of Melbourne have significantly advanced understanding of a virus that kills up to half a million children each year.

A five-year research partnership between the London School of Hygiene & Tropical Medicine and the University of California, Los Angeles (UCLA) has revealed the atomic-level structure of the bluetongue virus (BTV), a disease ...

Vaccine developers have successfully protected mice against Zika by injecting synthetic messenger RNA that encodes for virus proteins into the animals. The cells of the mice then build parts of the virus, training the immune ...

Our immunosensory system detects virus such as influenza via specific characteristics of viral ribonucleic acid. Previously, it was unclear how the immune system prevents viruses from simply donning molecular camouflage in ...

Using nanotechnology and a patented signal enhancing technique developed at the University of Georgia, UGA researchers have discovered a rapid, sensitive and cost-effective method to detect and identify a number of rotavirus ...

Bioengineers at the University of California San Diego have developed a new tool to identify interactions between RNA and DNA molecules. The tool, called MARGI (Mapping RNA Genome Interactions), is the first technology that's ...

Small "bubbles" frequently form on membranes of cells and are taken up into their interior. The process involves EHD proteins - a focus of research by Prof. Oliver Daumke of the MDC. He and his team have now shed light on ...

Scientists from The University of Western Australia have identified a tiny mutation in plants that can influence how well a plant recovers from stressful conditions, and ultimately impact a plant's survival.

The first skirmish was fought last week in what could be a long war over a revolutionary patent on gene-editing technology, with colossal amounts of money at stake.

Waterhemp has been locked in an arms race with farmers for decades. Nearly every time farmers attack the weed with a new herbicide, waterhemp becomes resistant to it, reducing or eliminating the efficacy of the chemical. ...

The last Neanderthal died 40,000 years ago, but much of their genome lives on, in bits and pieces, through modern humans. The impact of Neanderthals' genetic contribution has been uncertain: Do these snippets affect our genome's ...

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Plantbot Genetics Talk, Exhibit Start Conversations About Green Issues – WUWF

Artists Wendy DesChene and Jeff Schmuki run Plantbot Genetics, a parody of a biotech corporation that develops combinations of robots and plants. Their mission: Spark a discussion about the environment.

The Plantbot duo delivered a presentation recently at First City Art Center in downtown Pensacola.

The talk was part of STEAM2017, a five-week program of lectures, workshops and talks with artists and scientists sponsored by the College of Arts, Social Sciences and Humanities at the University of West Florida. STEAM2017 explores how art adds to the disciplines of science, technology, engineering and math to examine issues related to the environment.

We use silly singing and dancing plants to call attention to serious issues, Schmuki said. Humor is a way to engage people and get them to listen to your message.

Schmuki and DesChene talked to the crowd of more than 100 people for about an hour. Topics ranged from planting native wildflowers and avoiding the use of chemical pesticides to helping counteract the declining bee population.

Its about being aware of whats happening in your own backyard, DesChene said.

She encouraged attendees to think of themselves as powerful.

When it comes to environmental issues, people often get overwhelmed and think of the problems as too big, DesChene said. Thats not true. Just think of the example of the water bottle.

DesChene explained that during her lifetime, she has seen people go from not drinking bottled water at all during the 1970s to seeing it become ubiquitous during the 1980s.

By the 1990s we were asking ourselves what we were going to do with all the plastic bottles. And now, today, we see that there are opportunities to recycle plastic bottles all over the place. So we have solved that problem over the course of 30 years.

DesChene said the evolution of how we think of reusing water bottles illustrates that people can make a difference in the environment.

We change as a society; we arent stuck with our bad habits, she said. As long as people are aware of the problems and talking about them, we have a chance to make a difference.

Talking about the environment is the point of any Plantbot exhibit, which DesChene and Schmuki stage all over the country in their portable trailer. People who attend their talks can walk through the trailer and ask questions.

We are all about starting a conversation, Schmuki said.

When they are not presiding over a Plantbot exhibit out of their trailer, Schumki teaches ceramics at Georgia Southern University, and DesChene teaches painting and drawing at Auburn University.

I like how they merge science and art to get peoples attention, said Madi Heinze, a junior majoring in studio art at UWF who attended the talk at First City Arts Center.

Others who attended the talk commented about the usefulness of the information disseminated during the Plantbot presentation.

Im getting into gardening, and I want to do it in an environmentally friendly way, said Cooper Dalrymple, a student at Pensacola State College. Its important to keep your eye out for information, thats why I came to the presentation. It was interesting to hear about organic pesticides. I am growing rosemary, thyme, basil and cilantro and tomatoes in my little backyard garden, so I can use definitely use the tips I heard about tonight. I think its important to help out the environment in any way that you can.

This article is part of a collaboration between WUWF and the UWF Center for Research and Economic Opportunity.

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Plantbot Genetics Talk, Exhibit Start Conversations About Green Issues - WUWF