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The DNA of oil wells: U.S. shale enlists genetics to boost output … – Reuters

HOUSTON A small group of U.S. oil producers has been trying to exploit advances in DNA science to wring more crude from shale rock, as the domestic energy industry keeps pushing relentlessly to cut costs and compete with the world's top exporters.

Shale producers have slashed production costs as much as 50 percent over two years, waging a price war with the Organization of the Petroleum Exporting Countries (OPEC).

Now, U.S. shale producers can compete in a $50-per-barrel oil market, and about a dozen shale companies are seeking to cut costs further by analyzing DNA samples extracted from oil wells to identify promising spots to drill.

The technique involves testing DNA extracts from microbes found in rock samples and comparing them to DNA extracted from oil. Similarities or differences can pinpoint areas with the biggest potential. The process can help cut the time needed to begin pumping, shaving production costs as much as 10 percent, said Ajay Kshatriya, chief executive and co-founder of Biota Technology, the company that developed this application of DNA science for use in oilfields.

The information can help drillers avoid missteps that prevent maximum production, such as applying insufficient pressure to reach oil trapped in rocks, or drilling wells too closely together, Kshatriya said.

"This is a whole new way of measuring these wells and, by extension, sucking out more oil for less," he said.

Biota's customers include Statoil ASA, EP Energy Corp and more than a dozen other oil producers. Kshatriya would not detail Biota's cost, but said it amounts to less than 1 percent of the total cost to bring a well online.

A shale well can cost between $4 million and $8 million, depending on geology and other factors.

Independent petroleum engineers and chemists said Biota's process holds promise if the company can collect enough DNA samples along the length of a well so results are not skewed.

"I don't doubt that with enough information (Biota) could find a signature, a DNA fingerprint, of microbial genomes that can substantially improve the accuracy and speed of a number of diagnostic applications in the oil industry," said Preethi Gunaratne, a professor of biology and chemistry at the University of Houston.

Biota has applied its technology to about 80 wells across U.S. shale basins, including North Dakota's Bakken, and the Permian and Eagle Ford in Texas, Kshatriya said. That is a tiny slice of the more than 300,000 shale wells across the nation.

EP Energy, one of Biota's first customers, insisted on a blind test last year to gauge the technique's effectiveness, asking Biota to determine the origin of an oil sample from among dozens of wells in a 1,000-square foot zone.

Biota was able to find the wells from which the oil was taken and to recommend improvements for wells drilled in the same region, said Peter Lascelles, an EP Energy geologist.

"If you've been in the oilfield long enough, you've seen a lot of snake oil," said Lascelles, using slang for products or services that do not perform as advertised.

Lascelles said DNA testing helps EP Energy understand well performance better than existing oil field surveys such as seismic and chemical analysis. The testing gives insight into what happens underground when rock is fractured with high pressure mixtures of sand and water to release trapped oil.

Biota's process is just the latest technology pioneered to coax more oil from rock. Other techniques include microseismic studies, which examine how liquid moves in a reservoir, and tracers, which use some DNA elements to study fluid movement.

Venture capitalist George Coyle said his fund Energy Innovation Capital had invested in Biota because it expected the technique to yield big improvements in drilling efficiency. He declined to say how much the fund had invested.

"The correlations they're going to be able to find to improve a well, we think, are going to be big," he said.

-For graphic on 'DNA sequencing in the oil industry' click: tinyurl.com/ma8ypwd

(Reporting by Ernest Scheyder; Editing by Gary McWilliams, Simon Webb and David Gregorio)

HOUSTON/CARACAS Venezuela is negotiating financial help from Russian oil major Rosneft to complete nearly $3 billion in PDVSA debt payments coming due to bondholders next month, two market sources and a government source familiar with the talks told Reuters on Friday.

WASHINGTON U.S. farmers plan to seed a record amount of soybean acreage this spring, even with supplies trending near all-time highs, but wheat seedings will fall to the lowest on record, the government said on Friday.

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The DNA of oil wells: U.S. shale enlists genetics to boost output ... - Reuters

Biology lecture at BGSU – Sentinel-Tribune

Posted: Friday, March 31, 2017 11:07 pm

Biology lecture at BGSU By Sentinel-Tribune Staff Sentinel-Tribune

Dr. Scott Gilbert, professor of biology at Swarthmore College, will discuss his research about ecological developmental biology for the 2017 Jean Pasakarnis-Buchanan Lecture on campus Tuesday.

Ecological developmental biology brings together aspects of embryology, medical physiology, ecology and evolution. Gilbert will present Eco-Evo-Devo: The Synthesis of Epigenetics, Medicine and Evolution at 7 p.m. in the Bowen-Thompson Student Union Theater (Room 206). Gilbert, who is the Howard A. Schneiderman Professor of Biology, is known for his work in developmental genetics, embryology, and the history and critiques of biology. During his public presentation, he will discuss his research, which includes the origin of evolutionary novelties, history of biology and its social functions. The lecture is free and open to the public.

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Posted in Community on Friday, March 31, 2017 11:07 pm.

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Biology lecture at BGSU - Sentinel-Tribune

Q&A: Monica Grady ’17 – Boston College Chronicle

How do your studies in biochemistry and music complement one another?

Both disciplines have helped me develop analytical skills. For instance, in biochemistry I often have to break down a molecular process by asking myself how I can connect this reaction to something I already know, so I can understand the concept more fully. And in music, the thought process is similar: How can I think of these notes what images or experiences can I tie to them so that I can maximize the expressivity of a phrase? The problem-solving I do in one subject stretches my capacity to do the same in the other.

What musical piece did you play in the BC Symphony Orchestra Concerto Competition? Do you prefer a particular composer?

I played Cello Concerto No. 1 in A minor by Camille Saint-Sans [which she also performed in the recent concert]. When it comes to solo repertoire, I love Edward Elgars Cello Concerto in E minor. The Elgar encompasses a broader range of expression both technically and musically and forces the performer to access and communicate raw, inner emotions in a very unique way.

Tell us about your experience with the BC Symphony Orchestra.

I have played with the Boston College Symphony Orchestra since freshman year. It has been great to have the opportunity to play significant symphonic works in a non-conservatory setting. [Director] John Finney has very realistic expectations of what the BCSO can do, and does an excellent job making the most of the skills that the orchestra members have. It was an incredibly rewarding experience rehearsing and performing alongside fellow BC musicians and friends, some of whom I have played with for the past four years here.

Have other BC faculty members have influenced you, and in what ways?

My conversations with [Music] Professor Thomas Oboe Lee led me to shift my conception of cello as an extracurricular to something that is a central aspect of my life. Professor Lee was the first to make me consider pursuing music. Now that I have embraced the idea of music as a very serious possibility for the future, I am much happier.

How did your semester in Italy contribute to your creative development?

I studied art history, Italian cinema, European history, and Italian language at the University of Parma, and did an internship at the Pietro Barilla Childrens Hospital. In Italy I was confronted with art everywhere I turned in the conventional forms of painting, sculpture, architecture, but also in terms of food, fashion, and language. Being exposed to art in this way distanced me from my stresses and allowed me return back to my normal life with the attitude of searching for beauty in what I see and what I do.

What are your post-graduate plans? Do they include music?

My post-graduate plans remain undecided. Medical school has always been a consideration, but for now I know that I would not be satisfied by simply doing cello for pleasure and allowing my skill level to stagnate. I would like to continue a serious study of the cello and see where it may take me.

Rosanne Pellegrini / University Communications

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Q&A: Monica Grady '17 - Boston College Chronicle

The anatomy and opportunity of halving a PE – The Australian Financial Review

Dushko Bajic, the new head of equities at Colonial First State Global Asset Management.

For Dushko Bajic, a centralinvestment rule is this: in uncertain times, you have to hold the courage of your convictions.

"When the market gets in a funk, it double counts, triple counts," says Colonial First State Global Asset Management's new head of equities, who oversees $10.8 billion in funds under management at one of the market's largest growth managers.

Take DavidTeoh'sTPG Telecom. The stock a long-time market darling was beaten up in the second half of last yearafter a profit downgrade which quickly led to many investors reversing their long-held view thatTeohwas a master capitalallocatorand business builder.

In particular, concerns linger about TPG's strategy of expanding into the Singapore market though Bajic argues that, like many of the concerns relating to TPG, they are overdone.

"In a market like 2015it would have been 'Look at whatTeohhas done in Australia, he'll do it in Singapore'," he says. "Nowit's maybe it's different market, maybe it's a distraction, maybe they need to do a capital raising ... it's the anatomy of halving a PE."

TPG was also a target of short-sellers, though Bajic is pragmatic about that market dynamic.

"I'm happy for shorters to exist and to createefficiency and inefficiency, which sometimes means a good buying price. One of the remaining sources of competitive advantage is being able to be patient investors, which we're committed to being," he says.

As an investment style, growth isn't exactly flavour of the moment.The 2016 calendar yearwas the worst for quality and growth in 15 years, according toRealindex.

Since Bajic joined CFSGAM, the concentratedAustralian share fund return is 9.6 per cent per annum, compared to 9.2 per cent for the S&P/ASX 200 benchmark over the same period.

While Bajic may have a relatively low profile for someone who manages such a large fund, he has worked in financial markets since his first job as an analyst at Credit Suisse Asset Management.

Before joining Colonial nearly three years ago, the 43-year-oldBajichad worked at boutique Orion Asset Management with Tim Ryan.

Orion, which at its peak had funds under management of about $7 billion, ultimatelyclosed in 2013because of underperformance and an association with a high-profile insidertrading case.

Bajicsays there is much that was attractive about moving to Colonial the emphasis on strong research, the growth investment style and an existingstrong team.

But, ultimately, there was one moment which really convinced him he would take the role as deputy to Colonial's then head of equities, Marcus Fanning, in July 2014 with the understanding Fanning was grooming his successor.

"The way we convinced each other was we compared old portfolios," hesays."The ultimate measure is howsimilar your investment portfolio is."

In terms of macro, Bajicis sceptical about the impact being attributed toTrump reflation trade, arguing that better-than-expected economic growth in Europe, the US and China had begun before the new US president was elected and that was the key marketdynamic.

It was that view that led him to go overweight the two largest sectors in the market banks and resources last year.

Resources stocks arealways beneficiaries of economic growth, though Bajicnotes the performance would be far stronger if they had the disciplinedcapital allocation oftheir banking peers.

Bajicargues banks can organically generate the capital they need to meet their capital targets for the next three years, even if net interest margins are flat or decline.

And the banking regulator's decision to tighten lending by the banks on Friday?

Bajic says restrictions on interest-only lending to 30 per cent of new residential lending is significant, noting it contributes about 40 per cent of mortgage approvals at the moment. But he's broadly supportive.

"It makes sense to me. The result will be less of the type of credit growth you don't want and debt in the hands of those who can afford it. It won't choke off credit for new supply and that's important for keeping houses prices in check with incomes," he says.

Bajicsays REA Group is one stock he's added to the portfolio, on the basis that there's still plenty of advertising spend they will be able to capture. And he's impressed with the management team.

He also highlightsAristocrat Leisure which the fund has owned for averylong time asanother stock helikes for its recurringrevenueand its success in identifying and offsetting zombie machine risk by moving into the online market.

Mayne Pharma is another out-of-favour growth stock Bajiclikes, arguing the proposed Trump healthcare reform should benefit, rather than hurt, the generics manufacturer as it would likely push more of the healthcare spend to that segment of the market.

Bajic says Colonial'sability to invest time in strong research particularlyat a time when broking firms andresearch analysts are under financial pressure and investing far less in experienced analysts wasanother reason for accepting the job at CBA's funds manager. And he acceptsthat hiring analysts as portfolio managers isn't usually seen as a strong hire.

"Good analysts don't 100 per cent make good PMs, but a subset of goodanalystsdomakegood PMs,"hesays, noting that analysts who have become heads of equities tend to transition particularlywell.

While he's big on the importance of always doing the research, Bajicnotes that it's not foolproof.

"Youshould always do the research, sometimes you get the wrong conclusion," he says. But equally importantly, markets move fast and he warns that analysts need to have the capacity to do both quick and long-dated research.

That's why he has some other key investment rules: frequent testing of the validity of the investment thesis and creating a culture and process that generates ideas.

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The anatomy and opportunity of halving a PE - The Australian Financial Review

Greys Anatomy Season Finale Instagram Spoilers – Refinery29 – Refinery29

A few of the actors have already revealed that this season won't end with a catastrophic event (no plane crashes, sorry), but we do know that there is major drama afoot, especially with Riggs and Maggie. The Grey Sloan crew was all smiles on set, however, so either they're great at compartmentalizing or there is nothing earth-shattering happening in the finale.

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Greys Anatomy Season Finale Instagram Spoilers - Refinery29 - Refinery29

San Francisco Giants and Halo Neuroscience Announce New Partnership – Yahoo Finance

SAN FRANCISCO, March, 29, 2017 /PRNewswire/ --The San Francisco Giants have partnered with Halo Neuroscience, a San Francisco-based company that develops neurotechnology to unlock human potential for both performance and medical applications.

The strength and conditioning staff for the Giants completed a successful proof-of-concept test of Halo Neuroscience's first product, Halo Sport, and measured accelerated gains in player performance. As a result, the Giants began to incorporate Halo Sport into the team's core training protocol.

"We are extremely excited to integrate Halo's neurostimulation technology into our core training regimen to improve and refine on-field player performance and athleticism," said Dave Groeschner, Head Athletic Trainer for the San Francisco Giants. "After testing the product internally, we've determined that incorporating Halo Sport 'Neuropriming' into our training programs produces measurable and significant results. "

The Giants first started working with Halo Neuroscience one year ago during the team's 2016 January Conditioning Camp in Phoenix, AZ. At this time, the team's coaches split top minor league prospects into two groupsone Halo and one control groupand then compared each group's progress across nine standard performance measures.

Training and testing lasted two weeks, during which all athletes completed the same program: twenty-minute warm-ups followed by sixty minutes or more of focused training to improve skill, speed, and power. Athletes in one group wore Halo Sport headsets during the 20-minute warm-up, whereas athletes in the other did not.

At the conclusion of the two-week period, the Halo Group saw the greatest improvements in speed workthe area most heavily emphasized during Neuropriming sessions with Halo Sport. In the 20-yard dash, for example, almost all the athletes tested demonstrated significant improvement after two weeks, versus athletes in the control group who only demonstrated modest improvement.

"Our goal with Halo was to improve our team's speed and explosiveness," said Geoff Head, Sports Science Specialist at the San Francisco Giants. "Overall, all players at camp showed general improvements in the testing parameters, but there was an additional increase in testing results in the players who used Halo Sport as compared to the players in the control groupespecially in the 20-yard dash."

As a result of these findings, the Giants will continue to implement Halo Sport to improve movement-based training for the athletes in the organization.

"As a San Francisco-based company, we are thrilled to be working with our hometown team. With the Giants' league-leading, innovation-based approach to player development, we were able to earn our way into their winning formula," said Dr. Daniel Chao, CEO and Co-Founder of Halo Neuroscience.

For more information about the San Francisco Giants' partnership with Halo Neuroscience, and to learn more about Halo Sport, please visit blog.haloneuro.com.

About Halo Neuroscience

Halo Neuroscience develops neurotechnology to unlock human potential for both performance and medical applications. The company's first product, Halo Sport, utilizes Neuropriming technology to accelerate the neurologic gains of strength and skill learning that result from athletic training. Halo is now used by teams and athletes from the military, Olympics, MLB, NBA, NHL, and NFL, in addition to thousands of other athletes, musicians, and gamers around the world.

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San Francisco Giants and Halo Neuroscience Announce New Partnership - Yahoo Finance

10x Genomics Launches New Immunology Kit for VDJ Analysis as It Eyes Translational Medicine Market – GenomeWeb

SAN FRANCISCO (GenomeWeb) 10x Genomics has launched a single-cell analysis kit for immune repertoire profiling. The first kit will begin shipping in April and will enable the analysis of the VDJ regions from human T cells, while a second kit that will be launched later in the second quarter will enable VDJ analysis of human B cells.

Also, in the second half of the year, the firm plans to enable the analysis of single immune cells from mice.

A trial upgrade to GenomeWeb Premium gives you full site access, interest-based email alerts, access to archives, and more. Never miss another important industry story.

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10x Genomics Launches New Immunology Kit for VDJ Analysis as It Eyes Translational Medicine Market - GenomeWeb

Robo Madness 2017: The Photos and Takeaways – Xconomy

Third times a charm and our third annual Robo Madness conference in Boston had plenty of that. (So did the first two.) From live robot demos to provocative discussions on the opportunities and challenges in artificial intelligence, our speakers really delivered on this years theme: A.I. Gets Real.

Huge thanks to our host, Google, whose venue and support seem to get stronger every year. Special thanks to our event sponsors, who made it all possible: GE, Harmonic Drive, iRobot, Mitsubishi Electric Research Laboratories, Cirtronics, and TriNet. And, of course, thanks to our speakers, attendees, and demo organizers, who are what the event is really about.

Also, a big shout-out to Keith Spiro Photography for the pictures above.

Now, on to a few takeaways from the day:

1. Self-driving vehicles are at peak hype. There are huge opportunities at stake, but some of the biggest problems have yet to be solved: data sharing, liability, urban infrastructure, accounting for human behavior. Not to mention the technology needs to improve. On the plus side, the money flowing into the sector will benefit robotics as a whole. And incremental advances will continue to boost vehicle safety.

2. Data ownership is the key issue in machine learning. Weve heard this before, but big companies access to datasee Google, Amazon, Facebook, Uber, Teslagives them a huge leg up in A.I. applications. Theres not much new under the sun in terms of algorithms, so startups opportunities are largely determined by their datasets and team expertise.

3. Humans will need to communicate their goals to A.I. systems. In a world where machines can do more and more, people need to lay out guidelines for their behavior. This is especially important given that deep learning systems are getting harder for humans to understand and predict. Which leads to

4. Wed better think about jobs and ethics now. Robotics companies would rather address inefficiencies and labor shortages in fields like logistics, manufacturing, and delivery. But it seems likely that some (and perhaps many) human jobs will eventually become automated. How will business and policy leaders empower the human side of this evolving relationship? Stay tuned.

Xconomys Jeff Engel contributed to this report.

Gregory T. Huang is Xconomy's Deputy Editor, National IT Editor, and Editor of Xconomy Boston. E-mail him at gthuang [at] xconomy.com.

Gregory T. Huang is Xconomy's Deputy Editor, National IT Editor, and Editor of Xconomy Boston. E-mail him at gthuang [at] xconomy.com.

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Robo Madness 2017: The Photos and Takeaways - Xconomy

How You Remember This Weekend’s Hangover Will Depend Genetics – SheKnows.com

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Studies have shown many times over that people with a family history of alcoholism may be predisposed to be at a greater risk of developing drinking problems. But what if genetics also impacts how you remember hangovers? At Keele University, psychologist Dr. Richard Stephens looked into exactly that.

The National Institute on Alcohol Abuse and Alcoholism has reported that people with a family history are four times more likely to develop a drinking problem. Stephens based his research on that statistic, but focusing more on whether hangovers have some sort of impact on this.

More:Dispatches From High School: Teens on Drinking Alcohol

Stephens and his team conducted two studies to test this theory. His first study included 142 people, with a small portion of them having a family history of problem drinking, where he had them complete a survey about their hangovers in the past year. This study found that those with alcoholism in their family background recalled more frequent hangover symptoms than those who didnt have any family history of problem drinking.

His second study was designed in the same way, except the participants were asked about hangover symptoms the morning directly after a night of drinking. The results showed that there were no greater signs of hangover symptoms in the participants with a family history of alcoholism than in those who did not.

More:Alcohol Is Never an Excuse For Sexual Assault Period

While the findings may seem cloudy, Stephens is relatively positive toward his research. To him, it seemed that people who [were] predisposed to develop problem drinking are no more susceptible to developing a hangover however, we found that such people appear to remember their hangovers more lucidly.

So, while the amount of hangovers experienced did not change, the results showed that individuals who have a family history of problem drinking or alcoholism are more clearly able to remember their hangovers or what those hangovers felt like than those who do not have that kind of background. Stephens hopes that this information can be used to help curb excessive drinking and facilitate the means to create programs or plans for managing alcohol consumption.

More:My Spouse and I Quit Drinking and It Changed Our Relationship

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How You Remember This Weekend's Hangover Will Depend Genetics - SheKnows.com

Surge in sperm donors after P&J highlights issue – Press and Journal

A surge in sperm donor applicants has been reported by north-east health chiefs thanks, in part, to the Press and Journal.

At the beginning of last month, we reported that NHS Grampian had launched a fresh drive to recruit male donors, because stocks in the regions only centre were being rapidly depleted.

It was understood there had been little or no improvement since it emerged in a 2013 freedom of information request that only two men regularly attended the Aberdeen Fertility Centre, based at Aberdeen Maternity Hospital.

However, since the article appeared, more than 40 men have joined the initiative.

Hazel McBain, donor programme co-ordinator at Aberdeen Fertility Centre, said: Weve had a good level of extra interest and we are really grateful to the Press and Journal for helping raise awareness and to the readers who have come forward so far.

Every year, we see a decline in the number of donors, so we really hope campaigns like this will help stop that trend.

Weve had around 40 potential donors contact us recently which is simply fantastic and will be welcome news for couple hoping to conceive.

NHS chiefs are offering healthy men between 18 and 41 up to 350 for donations.

In November 2013, the Press and Journal reported that couples were facing delays of up to two years to start fertility treatment because of the ongoing lack of sperm and egg donors in the Aberdeen area.

It is thought much of the downturn in numbers was due to a controversial change in the law in 2005 which stripped men of their anonymity after a child turns 18.

The law means children conceived using donor eggs or sperm will be able to trace their biological parent if they choose to.

Ms McBain added that not everyone would be a successful applicant.

She said: We are bound by the Human Fertilisation and Embryology Authority regulations, so not everyone will meet the criteria.

That means we still really need men who are considering donating to come forward.

You can become a real hero by donating you are literally giving the gift of life. If you are unsure, have questions or want to have an informal chat about it, I would strongly encourage you to give us a ring at the Aberdeen Fertility Centre on 01224 553582.

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Surge in sperm donors after P&J highlights issue - Press and Journal