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Genetics

Animal Genetics Market Worth ($7,705.23 Mn by 2027) by (6.3% CAGR) with Impact of Coronavirus Outbreak and Global Analysis & Forecast by The…

Growth of Animal Genetics Market is attributed to rise in production of porcine and increase in pork consumption across the globe. The same segment is likely to register highest CAGR in the global animal genetics market during the forecast period.

PUNE, India, Nov. 25, 2021 /PRNewswire/ -- According to The Insight Partners study on "Animal Genetics Market to 2027 Global Analysis and Forecast by Animal Genetic Material, Genetic Material and Service" the animal genetics market was valued at US$ 4,778.67 million in 2019 and is projected to reach US$ 7,705.23 million by 2027; it is expected to grow at a CAGR of 6.3% during 20192027. The growth of the market is attributed to the growing preference for animal derived proteins supplements and food products and rising adoption of progressive genetic practices such as artificial insemination (AI) and embryo transfer. However, limited number of skilled professionals in veterinary research and stringent government regulations for animal genetics is expected to hinder the market growth.

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The North American region holds the largest market share of this market and is expected to grow in forecasted years. The growth in North America is characterized by the presence of new market players, various product launches and increasing government initiatives.

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Likewise, Mexico is likely to offer attractive business opportunities for livestock genetics. Over the last decades, Mexico's beef, pork, and dairy productions have undergone valuable developments. Mexican generators in the expanding livestock intensive systems are frequently using modern genetic improvement technologies such as artificial insemination and embryo transfers.

In North America, the US is the largest market for animal genetics market. Livestock groups provide consumers with different products and services, including meat, milk, eggs, fiber, and draught power. The genetic variation within livestock communities produces the raw material for evolving through natural selection in answer to changing conditions and human-managed genetic improvement plans. As per the Food and Agriculture Organization (FAO), animal genetics is one of the livestock development support. It is a wide field, ranging from characterization to conservation to genetic development. According to the National Institute of Food and Agriculture (NIFA), there have been dramatic improvements in animal production yields and efficiencies. Therefore, the ever-increasing demand for dietary protein in the United States has been observed. These demands are achieved by one the best Animal breeding is one strategy by which these improvements may be performed. NIFA, with the help of scientists from universities and research organizations and food animal industries, provides national leadership and funding opportunities to conduct basic, applied, and integrated research to increase knowledge of animal genetics and genomics.

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The COVID-19 outbreak has disturbed various trades and businesses across the world. The incidence of corona virus or COVID 19 has not yet been registered the animals. Also, there is no evidence that companion animals are the prime source of the spreading epidemic in humans. However, various studies have been conducted to check the spread of disease from animals to humans. In many cases, zoonotic diseases were found in humans due to interaction with animals. Therefore, government bodies are taking more precautions and safety measures to prevent the spread of corona virus in the animals. The measures are widely carried out for companion animals as they frequently come in contact with their owners. Also, it is essential to report the cases to a veterinary authority. For instance, in the region, to report the cases of detection of COVID-19 is done to OIE through WAHIS, in accordance with the OIE Terrestrial Animal Health Code as an emerging disease.

The OIE is actively working by providing assistance to research for their on-going research and other implications of COVID-19 for animal health and veterinary public health. The assistance is also providing risk assessment, risk management, and risk communication. Also, the OIE has put in place an Incident Coordination System to coordinate these activities. In addition, OIE is also working with the Wildlife Working Group and other partners to develop a long-term work program. The aims are to provide better understandings, dynamics, and risks around wildlife trade and consumption. Also, it aims to develop strategies to reduce the risk of future spillover events.

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Additionally, various product and service launches have been initiated, which is helping the US market to grow. For instance, The Veterinary Genetics Laboratory (VGL) at the UC Davis School of Veterinary Medicine has launched an updated and advanced website along with several new tests for veterinary community. As the VGL is one of the foremost genetic testing laboratories in the world, the new site and tests will bring yet another level of global impact to the top-ranked veterinary school. Thus, the consistent support for combating addiction in the country undertaken by various organizations likely to augment the growth of animal genetics market during the forecast years.

The Asia Pacific region is expected to be the fastest-growing region among all other regions. The growth of the market in the region is majorly due to countries like China, India and Japan, which drives the major consumption of animal derived products. Moreover, growing preference for animal derived proteins supplements and food products, and rising adoption of progressive genetic practices such as artificial insemination (AI) and embryo transfer are also likely to contribute to market growth. On the other hand, significant investment by government in various breeding programs is supporting the growth of market. For instance, the central and local governments have invested more than RMB 5 billion to build breeding or multiplier farms and conservation farms for breed improvement programs and the building of centers for testing the quality of breeding stock, semen, and embryos.

Based on product, the animal genetics market is segmented poultry, porcine, bovine, canine, and others. The porcine segment accounted for more than 35.84% of the market share in 2019. In terms of genetic material, the animal genetics market is segmented into semen, and embryo. The embryo segment held the largest share of the market in 2019. In terms of service, the animal genetics market is segmented into DNA typing, genetic trait tests, genetic disease tests, and others.The DNA typing segment held the largest share of the market in 2019.

Rising Adoption of Progressive Genetic Practices Such as Artificial Insemination (AI) and Embryo Transfer in Animal Genetics Market:

Growing focus on developing superior animal breeds using genetic engineering to obtain high reproduction rates for large-scale production of modified breeds is expected to drive animal genetics market during the forecast period. Animal genetics emphasizes the inheritance and genetic variations in wild and domestic animals. This science is used at a commercial level for services such as testing genetic disorders, screening genetic traits, and typing DNA. For identifying genetic hybridizations, animal genetics uses various genetic practices, such as artificial insemination, embryo transfer, and cytological studies. Moreover, artificial insemination (AI) can reduce various risks involved in animal breeding and disease transmission. It is found that female offspring cattle born through artificial insemination yield more milk than normal offspring. Additionally, the use of antibiotic-containing semen extensors is effective in preventing bacterial infectious diseases. Therefore, the entire AI process is considered hygienic than natural mating.

The market players are focusing on partnerships, collaboration, and acquisitions to develop genetically modified breeds and maintain their market share. For instance, in August 2020, Cogent and AB Europe collaborated to launch a novel sexed semen service for sheep producers in the UK. In May 2018, Recombinetics entered into partnership agreement with SEMEX for the implementation of a precision breeding program, which is expected to improve animal health and well-being through hornless dairy cattle genetics. According to the Brazilian Association of Artificial Insemination, the number of commercialized doses of semen increased from 7 million in 2003 to ~14 million in 2017. Thus, rising adoption of genetic practices will support the market growth in coming years.

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Market: Segmental Overview

In terms of product, porcine segment is anticipated to register the highest CAGR during the forecast period. Growing production of porcine and increase in pork consumption is likely to favor the growth of the market. Pork is the most consumed meat across the globe. In the US, pork production generates $23.4 billion output per year. Additionally, 26% that is around 2.2 million metric tons of pork and its products are exported to other countries. Despite of the challenges such as tariffs, labor and disease risks, the pork industry in US is still growing with around 66,000 sows in 2019. Also, developments by the major pork producers in the country is likely to grow the pork production industry. For instance, in 2017, 123-year-old Clemens Food Group partnered with 12 independent hog farmers to establish a new packing plant in Michigan. Thus, growing pork production industry is likely to favor market growth. In terms of genetic material, the animal genetics market is segmented into semen, and embryo. The embryo segment held the largest share of the market in 2019. In terms of service, the animal genetics market is segmented into DNA typing, genetic trait tests, genetic disease tests, and others.The DNA typing segment held the largest share of the market in 2019.

Animal Genetics Market: Competition Landscape and Key Developments

Neogen Corporation, Genus, Groupe Grimaud, Topigs Norsvin, Zoetis Services Llc, Hendrix Genetics Bv, Envigo, Vetgen, Animal Genetics Inc, Alta Genetics Inc. and among others are among the key companies operating in the animal genetics market. These players are focusing on the expansion and diversification of their market presence and the acquisition of a new customer base, thereby tapping prevailing business opportunities.

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In September 2020, Genus Plc and Tropic Bioscience entered into collaboration. Tropic Biosciences the pioneering agricultural-biotechnology company entered into collaboration with Genus in order to explore the application of Tropic's Gene Editing induced Gene Silencing (GEiGS) technology in porcine and bovine genetics.

In July 2020, Topigs Norsvin entered into strategic partnership with Acuity swine genetics company. This partnership will provide the opportunity for joint collaboration and expansion of technical expertise, commercial product testing and supply chain infrastructure in animal genetics market across the North America region.

In April 2020, Zoetis Animal Genetics and Angus Australia have entered into a strategic partnership that will aid Australian Angus breed stock and commercial breeders an additional benefit from genomic, or DNA-based technology. Zoetis have made a considerable investment in the expansion of the Angus genomic reference population through the provision of genotyping services and sponsorship.

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Genetics

Learn about your genetics for just $100 with this Cyber Monday 23andMe deal – Livescience.com

With this Cyber Monday 23AndMe deal, you can make a great saving as you delve into your ancestry. Have you ever wondered what parts of the world your family is from? What about what your DNA might tell you about which health issues you may be predisposed to? Well wonder no more, as this deal from Amazon gives 50% off the Health + Ancestry service a savings of $100 over its normal price.

23andMe created the first direct-to-consumer autosomal genetic testing product over a decade ago, and its testing on both ancestry and health is still one of the top options on the market right now. With the Health + Ancestry kit, you register your product, collect saliva, and send it back to the company for them to analyze.

Six to eight weeks later, you're given access to a range of results about your genetic ancestors. In your Ancestry Composition Report, youre shown how much of your DNA overlaps with 45 different worldwide genetic populations. Going way back, the report also shows you how much you may descend from Neanderthals, the group that interbred with homo sapiens potentially as recently as 47,000 years ago. The company also compares your DNA to that of people in over 150 countries, which may indicate where your more recent ancestors lived. For more discounts like this, head over to our Cyber Monday Ancestry DNA kit deals.

There is also the chance to opt-in to a service called DNA Relatives. This feature allows you to search for genetic members of your family and check which parts of your DNA overlap with theirs. You can search for relatives on either side of your family tree with this feature.

While there is a kit with just ancestry information alone, also on sale for 50% off today for Cyber Monday at Amazon, this package also includes health information such as carrier status and risk for certain conditions. For carrier status, the test checks to see whether you carry certain genes for conditions that can be passed down to your children, even though you may not have that particular health issue yourself. This 23andMe product also includes a Health Predisposition Report. This tells you whether you have a genetic variant that the company has associated with a higher risk of developing a disease such as Parkinsons or Alzheimers.

While some parts of the health testing in this kit have now been approved by the FDA, 23andMe notes that this analysis does not diagnose you and does not intend [to] tell you anything about your risk for developing a disease in the future. (Check out our 2018 article on what to know before taking 23andMes breast cancer test.) They also note that you should not change anything about your treatment for a disease based on this information, such as starting or stopping a medication. If you have any concerns about carrying a condition or your risk of developing a health issue, you should consult your doctor for medical advice.

With that being said, this test may be an interesting way to compare your genes to others, as the report also gives you information about wellness issues your genes may affect, such as how your body digests alcohol, caffeine, or lactose. The test also tells you if you are predisposed to certain traits like curly or wavy hair, or how you may perceive certain foods.

For more great savings, head over to our Cyber Monday binoculars deals.

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Learn about your genetics for just $100 with this Cyber Monday 23andMe deal - Livescience.com

Genetics

Webinars to focus on genetic conditions – The County

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Cary Medical Center, in partnership with The New England Regional Genetic Network, is teaming up with the Weitzman Institute to inspire primary care innovation in the screening and treatment of patients with genetic conditions.

CARIBOU, Maine Cary Medical Center, in partnership with The New England Regional Genetic Network, is teaming up with the Weitzman Institute to inspire primary care innovation in the screening and treatment of patients with genetic conditions.

Cary Medical Center received a grant from NERGN to help educate and connect underserved populations with resources and support related to genetic conditions, said Angel Murchison, grant outreach coordinator for the genetics program.

To better serve these communities, we are also promoting educational opportunities for primary care providers.

The NERGN Genetics webinar series will be offered by the Weitzman Institute, which aims to improve access to genetics services for underserved populations by offering primary care providers educational support through free webinars that enhance provider knowledge, practice, and attitudes regarding genetic services.

This series will also provide perspectives from other providers and participants in the New England area.

Webinar dates, times and topics are as follows.

Tuesday, Dec. 14, 12-1 p.m.: genetics referrals.

Tuesday, Jan. 11,12-1 p.m.: financial aspects of genetic testing.

Tuesday, Feb. 8, 12-1 p.m., newborn screening and genetic therapies.

Tuesday, March 8, 12-1 p.m., school-aged patients and considerations.

To register for one or all of these free seminars, visit chc1.zoom.us/webinar/register/WNUUKAgqr5QUGpb8caMKLgAg. Continuing education credits will be given for attending the live event.

Genetic webinars, as well as genetics-related ECHO sessions, will be archived on NERGNs website https://www.negenetics.org/professionals.

For more information visit http://www.negenetics.org.

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Webinars to focus on genetic conditions - The County

Genetics

Genetic Testing Services Market is Anticipated to Reach a Value of US$ 64.1Billion By the End of 2025 – BioSpace

Genetic Testing Services Market- Usage of Healthcare IT Provides Ample Expansion Opportunities, Finds Fact.MR

Fact.MRs latest report on Genetic Testing Services Market offers unbiased industry analysis for the period between 2020 and 2025. The study divulges exclusive information about existing opportunities and emerging trends across leading segments in terms of product, usage and end user. It also highlights various strategies employed by key manufacturers to gain edge in the market.

Fact.MR A Market Research and Competitive Intelligence Provider: According to the latest Fact.MR analysis, the global genetic testing services market size would reach US$ 64,131.4 million by 2025 and is expected to grow at a healthy CAGR of 7.6% between 2020 and 2025.

Genetic testing services have found widespread applications in several healthcare fields. These include oncology, obstetrics and ancestry. Genetic testing is predominantly used in determining the prevalence of various autoimmune diseases like rheumatoid arthritis, Type-1 diabetes mellitus, multiple sclerosis, cancers and Guillain-Barre syndrome.

On the back of these factors, the global genetic testing services market is set to burgeon in the future. The market is set to record robust expansion with a CAGR of 7.6% during the forecast period (2020-2025), surpassing a value of US$ 64,131.4 Mn by 2025. Increase in the number of geriatric patients and spread of communicable and non-communicable diseases are also anticipated to leverage the genetic testing services market.

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Key Takeaways of Global Genetic Testing Services Market:

By test-type, new born screening is set to expand rapidly during the forecast period, recording a CAGR of 8.4%. Increasing incidences of hyperthyroidism and other chronic diseases among infants is projected to boost this segment.

Hospital-based laboratories are set to gain maximum traction in the global genetic testing services market during the forecast period. This is attributed to the rising prevalence of hospitalization within the geriatric population who suffer from a number of ailments. The segment is anticipated to account for two-fifth of the overall genetic testing services market.

The oncology segment shall find maximum application for genetic testing services in the future. The segment shall register an impressive CAGR of 8% during the forecast period. Rising cases of cancer and increased awareness about early diagnosis is expected to drive the segments growth.

Autoimmune diseases segment shall gain significant traction, owing to importance of tracing hereditary-based factors responsible for the prevalence of diseases like cancers. The segment is projected to expand at a CAGR of 7.8%.

North America shall dominate the global genetic testing services market, owing to increased demand for knowing ancestry, in-vitro fertilization and pre-implantation testing. The region shall hold around two-fifth of the global genetic testing services market, registering a robust CAGR of 7% in the forecast period.

Asia-Pacific projects lucrative possibilities for the expansion of the global genetic testing services market. Rising prevalence of cancer and increased incidences of genetic disorders such as Huntingtons disease are expected to boost market share in the region. A robust CAGR of 8.4% is predicted for the region.

The COVID-19 pandemic is anticipated to stimulate the growth of the genetic testing services market. As hospitals are reaching a saturation point, key companies are investing in various genetic testing methods to assist healthcare professionals in diagnosing and treating COVID-19.

Recently, Avellino Lab USA announced additional production shifts to scale up the manufacturing of the SARS-CoV-2/COVID-19 Test. Christened AvellinoCoV2, this ultra-rapid genetic test helps clinicians diagnose COVID-19 by identifying and isolating the genetic markers as approved by the FDA and the CDC. It is highly reliable and accurate as well.

Likewise, MedGenome and SciGenom Research Foundation have published research into genetic susceptibility of the COVID-19 disease. The research concludes that there are variants in the ACE-2 gene that will help protect individuals from infection. The firms hope to eventually develop a potential drug based on these variants in collaboration with a suitable pharmaceutical company.

The global genetic testing services market shows prolific growth opportunities in the future. With increased prevalence of autoimmune diseases, patients are increasingly seeking solutions that help them determine hereditary anomalies and seek appropriate treatment. This is expected to majorly boost the market, concludes a Fact.MR analyst.

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Global Genetic Testing Services: Competition Landscape

The global genetic testing services market consists of the following players: Laboratory Corporation of America Holdings, Quest Genetics Incorporated, Genomic Health, Inc., NeoGenomics Laboratories, Inc., Eurofins Scientific, Ambry Genetics and 23andMe, Inc. Laboratory Corporation of America Holdings dominates the genetic testing services market. It provides specialty testing services in womens health, Genetic genetics, allergies, cardiovascular disease and cancer Genetics.

The company processes tests on more than 3 million patient specimens per week and serves hundreds of thousands of customers in the United States. Likewise, Quest Genetics Incorporated offers various Genetic and clinical tests for several medical conditions such as hepatitis C, arthritis, cardiovascular diseases, neurology, Genetics, Pediatrics, autoimmune diseases and cancers. The companys main area of expertise is in providing Genetic information services.

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The research study on the global genetic testing services market by Fact.MR incorporates an unbiased assessment of key factors and trends responsible for shaping the landscape of the global Genetic testing services market over 2020-2025. It includes a detailed assessment of key parameters that are anticipated to exert influence during 2020-2025. Market statistics have been presented on the basis of Test Types (Prenatal Testing, New Born Screening, Predictive and Presymptomatic Testing, Pharmacogenomic Testing & Others) Service Providers (Hospital-based Laboratories, Genetic Laboratories, Specialty Clinics and Others) & Applications (Oncology, Infectious Diseases, Autoimmune Diseases and Others) across five major regions.

Key Questions Answered in Fact.MR Genetic Testing Services Market Report

Which regions will continue to remain the most profitable regional markets for Genetic Testing Services market players?

Which factors will induce a change in the demand for pleural catheter manufacturers during the assessment period?

How will changing trends impact the Genetic Testing Services market?

How can market players capture the low-hanging opportunities in the Genetic Testing Services market in developed regions?

Which companies are leading the Genetic Testing Services market?

What are the winning strategies of stakeholders in the Genetic Testing Services market to upscale their position in this landscape?

Important Insights Enclosed in the Report:

Technological developments within the Genetic Testing Services market sphere

Growth prospects for new market players across different regions

Company profiles of leading players in the Genetic Testing Services market

Up-to-date insights related to the key success factors impacting the growth of the Genetic Testing Services market

Recent mergers, acquisitions, partnerships, and strategic alliances

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Global Genetic Testing Services Market Segmentation

Fact.MR has studied the global genetic testing services market with detailed segmentation on the basis of test types, service providers, applications and key regions.

Test types

Service providers

Applications

Key Regions

Explore Fact.MRs Coverage on the Healthcare Domain

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Genetic Disorder Therapeutics Market Analysis- Genetic Disorder Therapeutics Market Forecast, Trend Analysis & Competition Tracking - Global Market Insights 2018 to 2026

Animal Genetics Market Forecast- Animal Genetics Market Research Report Segmented By Product (Live Animals, Genetic Material, Genetic Testing), By Live Animals (Bovine, Porcine, Poultry, Canine, Piscine, Others), By Genetic Material (Semen, Embryo, Others), & By Region - Global Market Insights 2020 to 2026

About Fact.MR

Fact.MR is a market research and consulting agency with deep expertise in emerging market intelligence. Spanning a wide range from automotive & industry 4.0 to healthcare, technology to even the most niche categories. 80% of Fortune 1000's trust us in critical decision making.

MarketNgage is powered by Fact.MR our Unified Intelligence Engine, a revolutionary Market Research Subscription platform with a flexible pricing to suit your needs.

You can access all our healthcare research reports by signing up with MarketNgages Market Research Subscription with FREE credits. MarketNgage is powered by Fact.MR A Fully integrated research solution for seamless single-window access Widest coverage on emerging markets, nascent products, and disruptive technologies.

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Genetic Testing Services Market is Anticipated to Reach a Value of US$ 64.1Billion By the End of 2025 - BioSpace

Genetics

Genetics of the future: How Tyumen State University scientists solve biosafety issues – TASS

The Institute of Environmental and Agricultural Biology (X-BIO) at Tyumen State University is one of the research centers in Russia dealing with biosafety issues. This year, it will celebrate its fourth birthday. The decision to create the center was made by the university's scientific council on November 27, 2017. In this short time, X-BIO has managed to make itself known not only nationally, but internationally as well, becoming one of the university's flagships in scientific research.

Employees at the Institute participate in projects at the West Siberian Interregional Scientific and Educational Center, the Kuchak Lake Carbon Range Project, and create their own laboratories. Andrei Tolstikov, Senior Vice-Rector of Tyumen State University, told TASS about alternatives to antibiotics scientists are looking for, how biologists participate in the digitalization of agriculture and why we need to engage in bioethics.

X-BIO Institutes field of work

According to Tolstikov, the new institute was shaped by the events happening in the world. The global SARS-CoV-2 pandemic more commonly known as the new coronavirus, which broke out in 2020, numerous outbreaks of highly pathogenic avian influenza viruses, African swine fever and other dangerous diseases around the world, as well as yield losses of some crops due to diseases and pesticide resistant pests. All this has determined the vector of the new institute's development, Tolstikov said.

X-BIO is taking an active part in creating a world-class center for biosafety within the framework of the West Siberian Interregional Scientific and Educational Center and is implementing a number of projects within the framework of the Scientific and Educational Center for Human, Animal and Plant Biosafety.

As the senior vice-rector notes, the year 2020 was a significant one in the history of the institute, winning the project of the federal scientific and technical program for the development of genetic technologies under the leadership of West Siberian Interregional Scientific and Educational Centeracademician Andrei Lisitsa on the topic of microbiomes of agrocenoses. "Under the banner of the new project, six research teams from the X-BIO Institute got involved in solving problems to create an entirely new type of land management that can restore soil quality," Tolstikov said. Amongst their numerous projects, scientists are also working on Russia's first carbon test site at the university's biostation on Lake Kuchak.

Modern research in the hands of young people

By early next year, the Institute is expected to have new laboratories led by young researchers. In December, the ecological genetics and metagenomics laboratory, which was created on the money of the genetic technologiesgrant, will become operational and will be headed by Evgeny Simonov. Early next year, insect systematics and phylogenetics laboratory, headed by Maria Salnitskaya, will be launched. The laboratory, created as part of the Research Center, which deals with resource-efficient biomass processing technologies, is already beginning its work, headed by Ivan Shanenkov, an Alferov scholar.

"In addition, the X-BIO Institute will be the universitys central research uniting several "Priority 2030" Strategic Academic Leadership Program projects, which has received federal funding. These projects will address even larger tasks, expand the scientific agenda, and create long-term alliances with Russian and foreign partner organizations," Tolstikov says.

Why the work of the Institute is so important

The relevance of ensuring biological safety will only increase, according to Tyumen Universitys senior vice-rector. "Pathogens and pests are becoming more resistant to chemical agents. The so-called superbacteria are even found in Greenland and Antarctica, in the Amazon jungle. They are resistant to most antibiotics used in medicine and veterinary medicine. Finding new effective antibiotics in nature or synthesizing them is becoming increasingly difficult, and addiction to them is developing more and more rapidly," Tolstikov notes.

Traditional chemical agents are being replaced by biological methods of plant and animal protection. The Institutes antimicrobial resistance laboratory headed by Alexei Vasilchenko along with several groups of entomologists and acarologists is actively engaged in this work. The scientists are looking for new species of predatory insects and mites that can effectively regulate the number of pests of cultivated plants.

The role of biologists in the digitalization of agriculture

As Andrey Tolstikov notes, digitalization in agriculture is gaining momentum. The technical means to make this transition already exist, but they need to be adapted to specific agricultural enterprises. Specialists need to develop software and create specific package cases.

X-BIO is not on the sidelines. A search youth laboratory called AgroBioIT was created under the leadership of Aidar Fakhrutdinov. Its projects involve graduate and undergraduate students of various technical specialties. For example, they recently created a new product, a simulator for drone operators, which has already found customers and commercial prospects, said the senior vice-rector.

At the intersection of ethics and genetics

"The development of the latest technologies in the field of genetics must go together with the assessment of the ethical aspects of modifying biological and natural objects. Accordingly, there is an increased need for those specialists who can professionally evaluate these or other initiatives to introduce bioethics into training programs," Tolstikov believes.

According to him, the Institute is discussing plans to train personnel in bioethics.

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Genetics of the future: How Tyumen State University scientists solve biosafety issues - TASS

Genetics

Opinion | What I Learned Testing My Dogs DNA – The New York Times

Curiosity is a great motivator, but my curiosity about Rascals breed mix would have come to nothing had I not submitted to a DNA test myself shortly before we adopted him. I wasnt looking for my own genetic ancestry; Im wary of what such tests reveal and warier still of how their results might be used. Commercial DNA testing has revealed family secrets, solved crimes long consigned to the cold-case files, even affected census results.

From human genetics research particularly studies involving identical twins we know that DNA influences much of what we consider to be our most human traits: our personality, our preferences, our I.Q. Lay people, even many researchers themselves, tend to find such research troubling, hinting at a kind of genetic determination.

Despite the unresolved ethical and cultural issues raised by DNA testing, its potential medical benefits are remarkable. I have a rare inherited syndrome that almost certainly killed my paternal grandmother at 51 and accounted for my fathers cancer diagnosis in middle age. When I submitted a saliva sample to a medical lab for genetic testing, I was contributing to research that might identify the gene that causes the condition, saving future patients from the expensive and disruptive cancer screenings that I undergo every year.

All of which primed me to reconsider DNA testing when we adopted Rascal; canine DNA tests can also reveal certain inherited medical conditions. In January, our rescue dog Millie died of complications of epilepsy. If Rascal carries a genetic risk for something terrible but treatable, too, I wanted to know about it.

Following a recommendation from Wirecutter, which evaluated 17 DNA tests on the commercial market, I ordered one from Embark and sent in a sample of Rascals saliva. A couple of weeks later, I got his results: 35.9 percent Chihuahua, 34.4 percent poodle, 6.9 percent bichon fris and 22.8 percent supermutt, Embarks catchall term for trace amounts of DNA from distant ancestors. Rascals ancestors apparently include a collie, a Pekingese, a Shih Tzu and a Maltese terrier.

The test also revealed that Rascal carries two copies of a gene variant associated with disk disease. Even before the breed results arrived, I got an email from one of Embarks veterinary geneticists explaining the risks associated with this variant and recommending some mitigation strategies. Some of them, like using a harness on walks, were easy to do. Others, like discouraging jumping, were less so. Keeping this buoyant little dog earthbound is a fools errand, but I was extremely grateful for the detailed advice.

Breed mix remains a matter of indifference to me. What does it mean that my gentle granddog has a wolf somewhere deep within her lineage? Apparently nothing. Thats the mystery of individuality, even in dogs.

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Opinion | What I Learned Testing My Dogs DNA - The New York Times

Genetics

Why Some People Find It Harder to Be Happy, According to Science – ScienceAlert

The self-help industry is booming, fueled by research on positive psychology the scientific study of what makes people flourish.

At the same time, the rates of anxiety, depression and self-harm continue to soar worldwide. So are we doomed to be unhappy, despite these advances in psychology?

According to an influential article published in Review of General Psychology in 2005, 50 percent of people's happiness is determined by their genes, 10 percent depends on their circumstances and 40 percent on "intentional activity" (mainly, whether you're positive or not).

This so-called happiness pie put positive-psychology acolytes in the driving seat, allowing them to decide on their happiness trajectory. (Although, the unspoken message is that if you are unhappy, it's your own fault.)

The happiness pie was widely critiqued because it was based on assumptions about genetics that have become discredited. For decades, behavioral genetics researchers carried out studies with twins and established that between 40 percent and 50 percent of the variance in their happiness was explained by genetics, which is why the percentage appeared in the happiness pie.

Behavioral geneticists use a statistical technique to estimate the genetic and environmental components based on people's familial relatedness, hence the use of twins in their studies.

But these figures assumed that both identical and fraternal twins experience the same environment when growing up together an assumption that doesn't really hold water.

In response to the criticism about the 2005 paper, the same authors wrote a paper in 2019 that introduced a more nuanced approach on the effect of genes on happiness, which recognized the interactions between our genetics and our environment.

Nature and nurture are not independent of each other. On the contrary, molecular genetics, the study of the structure and function of genes at the molecular level, shows that they constantly influence one another.

Genes influence the behavior that helps people choose their environment. For example, extroversion passed from parents to children helps children build their friendship groups.

Equally, the environment changes gene expression. For example, when expecting mothers were exposed to famine, their babies' genes changed accordingly, resulting in chemical changes that suppressed production of a growth factor. This resulted in babies being born smaller than usual and with conditions such as cardiovascular disease.

Nature and nurture are interdependent and affect each other constantly. This is why two people brought up in the same environment may respond to it differently, meaning that behavioral genetics' assumption of an equal environment is no longer valid.

Also, whether or not people can become happier depends on their "environmental sensitivity" their capacity to change.

Some people are susceptible to their environment and so can significantly change their thoughts, feelings and behavior in response to both negative and positive events.

So when attending a wellbeing workshop or reading a positive psychology book, they may become influenced by it and experience significantly more change compared to others and the change may last longer, too.

But there is no positive psychology intervention that will work for all people because we are as unique as our DNA and, as such, have a different capacity for wellbeing and its fluctuations throughout life.

Are we destined to be unhappy? Some people might struggle a little harder to enhance their wellbeing than others, and that struggle may mean that they will continue to be unhappy for longer periods. And in extreme cases, they may never experience high levels of happiness.

Others, however, who have more genetic plasticity, meaning they are more sensitive to the environment and hence have an increased capacity for change, may be able to enhance their wellbeing and perhaps even thrive if they adopt a healthy lifestyle and choose to live and work in an environment that enhances their happiness and ability to grow.

But genetics does not determine who we are, even if it does play a significant role in our wellbeing. What also matters are the choices we make about where we live, who we live with and how we live our lives, which affect both our happiness and the happiness of the next generations.

Jolanta Burke, Senior Lecturer, Centre for Positive Psychology and Health, RCSI University of Medicine and Health Sciences.

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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Why Some People Find It Harder to Be Happy, According to Science - ScienceAlert

Immunology

Assistant, Department of Immunology and Allergology job with RUDN UNIVERSITY | 273626 – Times Higher Education (THE)

Department: Department of Immunology and AllergologyFaculty: Institute of MedicineEmployment: Part-time (0.25)

Requirements to the candidate

Required knowledge:

Requirements:

The position of assistant of the department is assigned to a person who possesses the following criteria:

Working conditions (job description, KPI)

Responsibilities:

Conditions:

Accommodation at RUDN

For the full term of the employment contract, invited scientists who passed the competitive selection are provided with a campus apartment of the University.

According to local documents of the University, the deadline for submitting applications for vacant positions of teaching staff is one month from the date of posting information on the website of RUDN.

10.01.2022

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Assistant, Department of Immunology and Allergology job with RUDN UNIVERSITY | 273626 - Times Higher Education (THE)

Immunology

Grouping of immunological T-cell receptors may be key to identifying patients’ history of infection – News-Medical.net

Grouping of pathogen-recognizing proteins on immune T cells may be key to identifying if someone has had an infection in the past, suggests a study published today in eLife.

While tests measuring antibodies against a pathogen are often used to detect signs of a previous infection, it is more difficult for researchers to measure the strength and targets of a person's T-cell response to infection or vaccination, but the findings hint at a potential new approach. This patient information could one day be useful for detecting infections, guiding treatments or supporting the research and development of new therapies and vaccines.

Immune T cells help the body find and destroy harmful viruses and bacteria. Proteins on the outer surface of T cells called receptors allow the T cells to recognize and eliminate human cells that have been infected by specific pathogens.

While the abundance of specific receptors could provide clues about past infection, the enormous molecular diversity of T-cell receptors makes it incredibly challenging to assess which receptors recognise which pathogens. Not only is each pathogen recognised by a distinct set of receptors, but each individual develops a personalised set of receptors for each pathogen. We developed a new computational approach that allows us to find similarities among pathogen-specific T-cell receptors across individuals. Ultimately, we hope this will help develop signatures of past infection despite the enormous diversity of T-cell receptors."

Koshlan Mayer-Blackwell, Study First Author and Senior Data Scientist, Fred Hutchinson Cancer Research Center

The team tested their approach using data from the immuneRACE study of T-cell receptors in patients with COVID-19. Using their new software for rapidly comparing large sets of receptors, they were able to generate 1,831 T-cell receptor groupings based on similarities in the receptors' amino acid sequences that suggest they have similar functions.

In an independent group of COVID-19 patients, the team found that the common molecular patterns associated with receptor groupings were more robustly detected than individual receptor sequences that were previously hypothesised to recognise parts of the SARS-CoV-2 virus, demonstrating a major improvement on existing approaches.

"Our study introduces and validates a flexible approach to identify sets of similar T-cell receptors, which we hope will be broadly useful for scientists studying T-cell immunity," Mayer-Blackwell says. "Grouping receptors together in this way makes it possible to compare responses to infection or vaccination across a diverse population."

To help other researchers use this approach to develop T-cell biomarkers with their own data, the team has created free customisable software called tcrdist3.

"Our software provides flexible tools that will enable scientists to analyse and integrate the rapidly growing libraries of T-cell receptor sequencing data that are needed to identify the features of pathogen-specific T-cell receptors," concludes senior author Andrew Fiore-Gartland, Co-Director of the Vaccines and Immunology Statistical Center at the Fred Hutchinson Cancer Research Center. "We hope it will open new opportunities not only to identify patients' immunological memories of past infections and vaccinations but also to predict their future immune responses."

Source:

Journal reference:

Mayer-Blackwell, K., et al. (2021) TCR meta-clonotypes for biomarker discovery with tcrdist3 enabled identification of public, HLA-restricted clusters of SARS-CoV-2 TCRs. eLife. doi.org/10.7554/eLife.68605.

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Grouping of immunological T-cell receptors may be key to identifying patients' history of infection - News-Medical.net

Immunology

Research Fellow in Cancer Immunology job with UNIVERSITY OF SOUTHAMPTON | 273475 – Times Higher Education (THE)

Cancer Sciences

Location: Southampton General HospitalSalary: 31,406 to 37,467 Per annumFull Time Fixed Term for 12 monthsClosing Date: Tuesday 14 December 2021Interview Date: To be confirmedReference: 1620021CM

Antibody and Vaccine Group, Centre for Cancer Immunology, University of Southampton, Faculty of Medicine, School of Cancer Sciences

The Antibody and Vaccine Group based in the recently opened Centre for Cancer Immunology in Southampton has a strong track-record in basic and translational immunology. One of its central aims is to develop new and more effective antibody reagents for treating cancer.

An exciting opportunity now presents itself for a research fellow to work on a Cancer Research UK funded programme to determine how a family of key receptors (Fc receptors) are regulated and serve to deliver antibody-mediated cancer cell destruction. The post-holder will leverage expertise in antibody biology, myeloid cells, transcriptomics, immunology, and cell biology in order to gain new understanding of this critical receptor family with the aim of improving cancer treatments.

You will be motivated, educated to PhD level in a relevant subject area and ideally have practical laboratory experience of antibody biology, myeloid cells, bioinformatics and in vivo methodology.

Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.

This post is offered on a full-time fixed term contract for 12 months.

Informal queries should be directed to Professor Mark Cragg (msc@soton.ac.uk)

Details about the School of Cancer Sciences and Centre for Cancer Immunology can be found at http://www.southampton.ac.uk/medicine/research/themes/cancer-sciences.page

Application Procedure

You should submit your completed online application form at https://jobs.soton.ac.uk. The application deadline will be midnight on the closing date stated above. If you need any assistance, please call Michelle (HR Recruitment Team) on +44 (0) 23 8059 2750 or email recruitment@soton.ac.uk Please quote reference 1620021CM on all correspondence.

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Research Fellow in Cancer Immunology job with UNIVERSITY OF SOUTHAMPTON | 273475 - Times Higher Education (THE)