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Neuroscience

Cognitive Impairment From Severe COVID-19 Equivalent to 20 Years of Aging – Neuroscience News

Summary: Severe COVID-19 infection results in cognitive impairment similar to that sustained by natural aging between the ages of 50 to 70, and is equivalent to losing 10 IQ points.

Source: University of Cambridge

Cognitive impairment as a result of severe COVID-19 is similar to that sustained between 50 and 70 years of age and is the equivalent to losing 10 IQ points, say a team of scientists from the University of Cambridge and Imperial College London.

The findings, published in the journaleClinicalMedicine, emerge from theNIHR COVID-19 BioResource. The results of the study suggest the effects are still detectable more than six months after the acute illness, and that any recovery is at best gradual.

There is growing evidence that COVID-19 can cause lasting cognitive and mental health problems, with recovered patients reporting symptoms including fatigue, brain fog, problems recalling words, sleep disturbances, anxiety and even post-traumatic stress disorder (PTSD) months after infection. In the UK, a study found that around one in seven individuals surveyed reported having symptoms that included cognitive difficulties 12 weeks after a positive COVID-19 test.

Whileeven mild cases can lead to persistent cognitive symptoms, between a third and three-quarters of hospitalised patients report still suffering cognitive symptoms three to six months later.

To explore this link in greater detail, researchers analysed data from 46 individuals who received in-hospital care, on the ward or intensive care unit, for COVID-19 at Addenbrookes Hospital, part of Cambridge University Hospitals NHS Foundation Trust. 16 patients were put on mechanical ventilation during their stay in hospital. All the patients were admitted between March and July 2020 and were recruited to the NIHR COVID-19 BioResource.

The individuals underwent detailed computerised cognitive tests an average of six months after their acute illness using the Cognitron platform, which measures different aspects of mental faculties such as memory, attention and reasoning. Scales measuring anxiety, depression and post-traumatic stress disorder were also assessed. Their data were compared against matched controls.

This is the first time that such rigorous assessment and comparison has been carried out in relation to the after effects of severe COVID-19.

COVID-19 survivors were less accurate and with slower response times than the matched control population and these deficits were still detectable when the patients were following up six months later.

The effects were strongest for those who required mechanical ventilation. By comparing the patients to 66,008 members of the general public, the researchers estimate that the magnitude of cognitive loss is similar on average to that sustained with 20 years aging, between 50 and 70 years of age, and that this is equivalent to losing 10 IQ points.

Survivors scored particularly poorly on tasks such as verbal analogical reasoning, a finding that supports the commonly-reported problem of difficulty finding words. They also showed slower processing speeds, which aligns with previous observations post COVID-19 of decreased brain glucose consumption within the frontoparietal network of the brain, responsible for attention, complex problem-solving and working memory, among other functions.

Professor David Menon from the Division of Anaesthesia at the University of Cambridge, the studys senior author, said: Cognitive impairment is common to a wide range of neurological disorders, including dementia, and even routine aging, but the patterns we saw the cognitive fingerprint of COVID-19 was distinct from all of these.

While it is now well established that people who have recovered from severe COVID-19 illness can have a broad spectrum of symptoms of poor mental health depression, anxiety, post-traumatic stress, low motivation, fatigue, low mood, and disturbed sleep the team found that acute illness severity was better at predicting the cognitive deficits.

The patients scores and reaction times began to improve over time, but the researchers say that any recovery in cognitive faculties was at best gradual and likely to be influenced by a number of factors including illness severity and its neurological or psychological impacts.

Professor Menon added: We followed some patients up as late as ten months after their acute infection, so were able to see a very slow improvement. While this was not statistically significant, it is at least heading in the right direction, but it is very possible that some of these individuals will never fully recover.

There are several factors that could cause the cognitive deficits, say the researchers.Direct viral infection is possible, but unlikely to be a major cause; instead, it is more likely that a combination of factors contribute, including inadequate oxygen or blood supply to the brain, blockage of large or small blood vessels due to clotting, and microscopic bleeds. However, emerging evidence suggests that the most important mechanism may be damage caused by the bodys own inflammatory response and immune system.

While this study looked at hospitalised cases, the team say that even those patients not sick enough to be admitted may also have tell-tale signs of mild impairment.

Professor Adam Hampshire from the Department of Brain Sciences at Imperial College London, the studys first author, said: Around 40,000 people have been through intensive care with COVID-19 in England alone and many more will have been very sick, but not admitted to hospital. This means there is a large number of people out there still experiencing problems with cognition many months later. We urgently need to look at what can be done to help these people.

Professor Menon and Professor Ed Bullmore from Cambridges Department of Psychiatry are co-leading working groups as part of theCOVID-19 Clinical Neuroscience Study (COVID-CNS)that aim to identify biomarkers that relate to neurological impairments as a result of COVID-19, and the neuroimaging changes that are associated with these.

Funding: The research was funded by the NIHR BioResource, NIHR Cambridge Biomedical Research Centre and the Addenbrookes Charitable Trust.

Author: Craig BrierleySource: University of CambridgeContact: Craig Brierley University of CambridgeImage: The image is in the public domain

Original Research: Open access.Multivariate profile and acute-phase correlates of cognitive deficits in a COVID-19 hospitalised cohort by Hampshire, A et al. eClinicalMedicine

Abstract

Multivariate profile and acute-phase correlates of cognitive deficits in a COVID-19 hospitalised cohort

Preliminary evidence has highlighted a possible association between severe COVID-19 and persistentcognitive deficits. Further research is required to confirm this association, determine whether cognitive deficits relate to clinical features from the acute phase or to mental health status at the point of assessment, and quantify rate of recovery.

46 individuals who received critical care for COVID-19 at Addenbrookes hospital between 10th March 2020 and 31st July 2020 (16 mechanically ventilated) underwent detailed computerised cognitive assessment alongside scales measuring anxiety, depression and post-traumatic stress disorder under supervised conditions at a mean follow up of 6.0 ( 2.1) months following acute illness.

Patient and matched control (N=460) performances were transformed into standard deviation from expected scores, accounting for age and demographic factors usingN=66,008 normative datasets. Global accuracy and response time composites were calculated (G_SScore & G_RT). Linear modelling predicted composite score deficits from acute severity, mental-health status at assessment, and time from hospital admission.

The pattern of deficits across tasks was qualitatively compared with normal age-related decline, and early-stagedementia.

COVID-19 survivors were less accurate (G_SScore=-0.53SDs) and slower (G_RT=+0.89SDs) in their responses than expected compared to their matched controls. Acute illness, but not chronic mental health, significantly predicted cognitive deviation from expected scores (G_SScore (p=0.0037) and G_RT (p=0.0366)).

The most prominent task associations with COVID-19 were for higher cognition and processing speed, which was qualitatively distinct from the profiles of normal aging and dementia and similar in magnitude to the effects of aging between 50 and 70 years of age. A trend towards reduced deficits with time from illness (r=0.15) did not reach statistical significance.

Cognitive deficits after severe COVID-19 relate most strongly to acute illness severity, persist long into the chronic phase, and recover slowly if at all, with a characteristic profile highlighting higher cognitive functions and processing speed.

This work was funded by theNational Institute for Health Research(NIHR) CambridgeBiomedical ResearchCentre (BRC), NIHR Cambridge Clinical Research Facility (BRC-1215-20014), the Addenbrookes Charities Trust and NIHR COVID-19 BioResource RG9402. AH is funded by theUKDementia Research Institute Care Research and Technology Centre and Imperial College London Biomedical Research Centre. ETB and DKM are supported byNIHRSenior Investigator awards.JBR is supported by theWellcome Trust(220258) and Medical Research Council (SUAG/051 G101400). VFJN is funded by an Academy of Medical Sciences/ The Health Foundation Clinician Scientist Fellowship. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care.

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Cognitive Impairment From Severe COVID-19 Equivalent to 20 Years of Aging - Neuroscience News

Neuroscience

A very specific kind of brain cell dies off in people with Parkinson’s – Science News Magazine

Deep in the human brain, a very specific kind of cell dies during Parkinsons disease.

For the first time, researchers have sorted large numbers of human brain cells in the substantia nigra into 10 distinct types. Just one is especially vulnerable in Parkinsons disease, the team reports May 5 in Nature Neuroscience. The result could lead to a clearer view of how Parkinsons takes hold, and perhaps even ways to stop it.

The new research goes right to the core of the matter, says neuroscientist Raj Awatramani of Northwestern University Feinberg School of Medicine in Chicago. Pinpointing the brain cells that seem to be especially susceptible to the devastating disease is the strength of this paper, says Awatramani, who was not involved in the study.

Parkinsons disease steals peoples ability to move smoothly, leaving balance problems, tremors and rigidity. In the United States, nearly 1 million people are estimated to have Parkinsons. Scientists have known for decades that these symptoms come with the death of nerve cells in the substantia nigra. Neurons there churn out dopamine, a chemical signal involved in movement, among other jobs (SN: 9/7/17).

But those dopamine-making neurons are not all equally vulnerable in Parkinsons, it turns out.

This seemed like an opportunity to really clarify which kinds of cells are actually dying in Parkinsons disease, says Evan Macosko, a psychiatrist and neuroscientist at Massachusetts General Hospital in Boston and the Broad Institute of MIT and Harvard.

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The tricky part was that dopamine-making neurons in the substantia nigra are rare. In samples of postmortem brains, we couldnt survey enough of [the cells] to really get an answer, Macosko says. But Abdulraouf Abdulraouf, a researcher in Macoskos laboratory, led experiments that sorted these cells, figuring out a way to selectively pull the cells nuclei out from the rest of the cells present in the substantia nigra. That enrichment ultimately led to an abundance of nuclei to analyze.

By studying over 15,000 nuclei from the brains of eight formerly healthy people, the researchers further sorted dopamine-making cells in the substantia nigra into 10 distinct groups. Each of these cell groups was defined by a specific brain location and certain combinations of genes that were active.

When the researchers looked at substantia nigra neurons in the brains of people who died with either Parkinsons disease or the related Lewy body dementia, the team noticed something curious: One of these 10 cell types was drastically diminished.

These missing neurons were identified by their location in the lower part of the substantia nigra and an active AGTR1 gene, lab member Tushar Kamath and colleagues found. That gene was thought to serve simply as a good way to identify these cells, Macosko says; researchers dont know whether the gene has a role in these dopamine-making cells fate in people.

The new finding points to ways to perhaps counter the debilitating diseases. Scientists have been keen to replace the missing dopamine-making neurons in the brains of people with Parkinsons. The new study shows what those cells would need to look like, Awatramani says. If a particular subtype is more vulnerable in Parkinsons disease, maybe thats the one we should be trying to replace, he says.

In fact, Macosko says that stem cell scientists have already been in contact, eager to make these specific cells. We hope this is a guidepost, Macosko says.

The new study involved only a small number of human brains. Going forward, Macosko and his colleagues hope to study more brains, and more parts of those brains. We were able to get some pretty interesting insights with a relatively small number of people, he says. When we get to larger numbers of people with other kinds of diseases, I think were going to learn a lot.

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A very specific kind of brain cell dies off in people with Parkinson's - Science News Magazine

Anatomy

Jesse Williams and Sarah Drew to Appear on Greys Anatomy Season Finale – Variety

The once-and-future Greys Anatomy super couple of Jackson and April played by Jesse Williams and Sarah Drew are set to appear on the finale of the medical dramas 18th season on May 26, Variety has confirmed.

Williams left Greys Anatomy last season, having played Jackson since the shows sixth season. Drew, whod departed the show in 2018, returned for a guest appearance in May 2021 to send Jackson off to his new life in Boston, where he was taking over his familys foundation. April ended up moving there with him, having ended her relationship with her husband.

The onscreen pair share a daughter, and their portmanteau is Japril and though Japril fans would love a spinoff show revolving around the two characters, an ABC spokesperson batted down that idea to Variety on Friday. Nor could ABC offer any other details about the context in which Jackson and April will appear on the finale episode.

Upon his departure last year, Williams told Deadline that hed be happy to return to the show as a guest star. Williams is currently starring on Broadway in Take Me Out. Varietys review this month called his performance impressive as the embodiment of charisma and cool, in the role of Darren, whose coming out the play revolves around.

When Williams left Greys Anatomy, he thanked its creator, Shonda Rhimes, showrunner Krista Vernoff, star Ellen Pompeo and executive producer Debbie Allen, who also plays Catherine Avery, Jacksons mother. In a statement toVarietythen, he said, As an actor, director and person, I have been obscenely lucky to learn so much from so many and I thank our beautiful fans, who breathe so much energy and appreciation into our shared worlds. The experience and endurance born of creating nearly 300 hours of leading global television is a gift Ill carry always. I am immensely proud of our work, our impact and to be moving forward with so many tools, opportunities, allies and dear friends.

Deadline was the first to report the news of Williams and Drews return.

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Jesse Williams and Sarah Drew to Appear on Greys Anatomy Season Finale - Variety

Anatomy

A shortage of cadavers at the anatomy lab – KUNM

For many people, the prospect of an anatomy lab full of corpses is disconcerting. But for first-year medical students, it can be exciting

"I remember the first time we walked in, you just get this sense of how big the moment is," said Alyssa Yock, who is studying at UNM medical school and tells me that all the reading in the world is no substitute for the slow, careful work of dissection of a real person.

"You know, you see things in a book, and you expect it to look like that," she said. "But when you get into a lab, you see that people are different, it's not always going to be how it is in the book."

But during the last two years, along with difficulties having students assembling safely in labs, the medical school has received fewer donations of people who had decided to give their bodies when they die.

Amy Rosenbaum, director of UNMs Anatomical Donations Program, explains why.

"Unfortunately, the pandemic shut us down for a while, we had to close," she said. "But the other aspect was that because of the pandemic, we can't take COVID-positive donorsSo that has really limited our pool.

It is a sensitive subject but Rosenbaum wants to remind people that the school is accepting donations and people can sign up to the program.

"It's really hard to advertise this, it's kind of a taboo subject," she said. "But there is a need. And I think that that's what we're trying to get out, is that there is a need for donation here."

The problem exists across the country. An article in the BMC Medical Education journal found that many schools nationwide stopped accepting donations during the pandemic, and about 80% of course directors said the pandemic affected the quality of learning, with many citing the absence of dissection as a problem.

Anatomy lecturer Julie Jordan says during the worst virus surges, the school explored online teaching options but would prefer not to rely on them

"We did use a virtual anatomy program that was cadaver based," she said. "It was pretty good. But it was ultimately really frustrating too, because you could only do so much with moving it around, and really investigating structures and function of the body."

Student Devin Maez learned online in his first year, during the worst of the pandemic, but assisted in the dissection lab in his second year and was grateful for the opportunity.

"There's something innately beautiful about learning hands on, that you don't get in a book," he said.

At the end of the course, the students learn more about their donors. Alyssa Yocky learned she had dissected a woman who had worked as a teacher, and as a nurse during wartime.

"I went in with one of my lab mates and we went and held her hand and it was like, I started to cry," she said. She hadn't expected to feel so emotional but was struck by, "just how much I learned from her and just thanking her for being such a great teacher."

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A shortage of cadavers at the anatomy lab - KUNM

Anatomy

Shows like Anatomy of a Scandal: 9 titles to watch next – Android Authority

Political drama Anatomy of a Scandal is one of Netflixs latest hits, jumping to number one on the streaming site. If youre won of the many people binging it, you may be looking for something similar. Thats why weve compiled a list of shows like Anatomy of a Scandal to watch next.

The miniseries follows the high-profile marriage of a British politician as he admits to his wife that hes had a soon-to-be-public affair. As the story develops, we learn that hes the subject of a far more serious investigation.

Check out: The best original streaming shows on every platform

Read on for nine recommended shows like Anatomy of a Scandal. And if you havent watched it yet, you can follow the link below.

Netflix

Netflix is still the leading premium streaming service, with over 200 million worldwide subscribers. It offers thousands of movies and TV shows to binge watch, including its always growing list of original films and series, including Stranger Things, The Witcher, Bridgerton, and many more.

Shows like Anatomy of a Scandal

Impeachment: American Crime Story

One of the biggest political scandals of the last few decades gets the American Crime Story treatment in Impeachment. While the Bill Clinton and Monica Lewinsky scandal was largely focused on the infidelity of a sitting president at the time, it has since been reexamined as a major abuse of power. The president sleeping with a much younger intern made for a major scandal either way, and this season of the anthology series explores the various angles of that abuse of power and its legal ramifications.

Hulu

Hulu offers not only thousands of movies and TV shows to stream, it also has original shows and films like The Handmaid's Tale. You can upgrade to Hulu Plus Live TV to get live channels, including your local stations.

The Morning Show

Apple TV Pluss flagship series, The Morning Show was among the first TV shows seen as a direct response to the Me Too and Times Up movements. In that way, its very much a show like Anatomy of a Scandal, which explores the changing ways we approach sexual misconduct. In The Morning Show, the staff of a morning news program grapple with revelations that one of the beloved hosts has a history of abuse.

Apple TV Plus

Apple TV Plus has quickly become a major player in the streaming game since its launch in 2019. Its slate of original programming includes shows like Ted Lasso, The Morning Show, Foundation, and For All Mankind as well as movies like The Banker, Greyhound, and Palmer.

A Very British Scandal

Also set in Britain and dealing with political scandal, A Very British Scandal looks back to the 1960s. When the Duke of Argyll files for divorce, the media are ready to pounce. But as they begin to dig, they uncover accusations of adultery, theft, violence, drug use, forgery, and bribery. This historical drama stars Paul Bettany and Claire Foy, and its likely to appeal to fans of Anatomy of a Scandal.

Amazon Prime Video

Amazon Prime Video offers access to thousands of movies and TV shows to stream. That includes great original shows and movies like The Boys and The Tomorrow War. You can also sign up for other premium services within Amazon Prime Video.

Trust

Rich and powerful people have a nasty habit of getting caught up in various scandals. Such was the case with American oil tycoons the Gettys. Beginning in 1973 with the kidnapping of John Paul Getty III by the Italian mafia, the series explores the complex history of the family and the ways it was slowly corrupted by money over generations.

No one does British scandals quite like the Royal Family. This Netflix original series earns its spot on this list of shows like Anatomy of a Scandal by going behind the headlines and dramatizing some of the high-profile scandals that have followed the royals over the years. A Sweeping portrait of the British Crown across generations, the series is certainly covering more ground than that, but it does explore stories of infidelity by Prince Phillip and the more publicly scrutinized marital troubles of Princess Diana and Prince Charles.

Chronicling the slow dissolution of two marriages due to infidelity, The Affair is a smart and engaging drama from Showtime, with terrific performances by Ruth Wilson, Maura Tierney, Dominic West, and Joshua Jackson. When diner waitress Allison and would-be novelist Noah begin an affair, it takes both of their marriages in unexpected directions.

Peacock

NBCUniversal's Peacock streaming service offers a lot of great movies and TV shows to stream on demand, along with live news and sports. Best of all, you can watch lots of its content for free, or watch all of it with a paid subscription starting at just $4.99 a month.

The Girlfriend Experience

In season one of The Girlfriend Experience, loosely based on Steven Soderberghs 2009 film of the same name, a young sex workers life is turned upside down by a former client. She has to protect herself when her chosen career becomes public, threatening her budding legal career and her relationships to the people unaware of her work as a high-end escort.

Starz

Starz offers thousands of movies and TV shows to stream, including acclaimed exclusive original TV series.

Unbelievable

In a lot of ways, Unbelievable is not a show like Anatomy of a Scandal. Its not about politics or marriage or the media or anything like that. And its American. What it does have in common with its fellow Netflix original miniseries is that both tackle allegations of sexual assault and changing social attitudes around believing victims. In Unbelievable, a teen girls account of being raped by a home invader is dismissed, and shes even punished by police for her false claim. When two detectives begin connecting the dots, they slowly realize the girl was revictimized by a horribly broken justice system.

An engrossing legal drama, The Good Wife sees a former defence attorney returning to work when her politician husband is sent to prison following a sex and corruption scandal. Taking control of her life, she rises above the humiliation by earning back her reputation as a lawyer. The Good Wife was partly inspired by the real-life Eliot Spitzer and John Edwards political scandals.

Paramount Plus

Paramount Plus includes thousands of movies and TV shows from CBS, Showtime, and Paramount Pictures. It also includes new and original movies like The Good Fight, Infinite, and more.

Thats our list of the best shows like Anatomy of a Scandal for you to check out if you enjoyed the Netflix miniseries. Well be sure to add titles if any new appropriate titles come out or make it onto our radar.

Netflix

Netflix is still the leading premium streaming service, with over 200 million worldwide subscribers. It offers thousands of movies and TV shows to binge watch, including its always growing list of original films and series, including Stranger Things, The Witcher, Bridgerton, and many more.

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Shows like Anatomy of a Scandal: 9 titles to watch next - Android Authority

Anatomy

Students Honor Those Who Donated Their Bodies for Anatomy Education – University of Colorado Anschutz Medical Campus

Eunice Spackman was born on her familys high plains homestead near Akron, Colorado. She rode a horse two miles to and from school each day, a path so familiar that the horse wouldnt deviate from it even when she wanted to go visit a friend.

Growing up during the Great Depression, she learned fundamental life skills like budgeting and homemaking, as well as the humility, independence, and generosity that guided her life. While building a life with her husband of 69 years, Everett, and raising their four sons, she was always lending a helping hand.

In a remembrance of his mother, Spackmans son Lowell wrote, Its very striking of moms values and unselfishness that her final gift was helping in education.

Were all part of something very special that happens when somebody makes that decision to will the use of their body in such an intimate way. - Mike Pascoe, PhD

Spackman was one of more than 150 people honored Wednesday evening in the Donor Memorial Ceremony, an annual event during which students from programs across the University of Colorado Anschutz Medical Campus honor and thank those who donated their bodies to the Colorado State Anatomical Board to support anatomy education.

Were all part of something very special that happens when somebody makes that decision to will the use of their body in such an intimate way, said Mike Pascoe, PhD, an associate professor of physical medicine and rehabilitation in the CU Physical Therapy Program and course director of clinical anatomy. I think everybody is impacted from the time the decision is made until the anatomy course is completed.

For Kate Kelson, a first-year student in the CU School of Medicine, entering the anatomy lab for the first time evoked a collage of emotions excitement, trepidation, nervousness. She remembers gathering with her classmates around their donors body for the first time and, during a minute of silence to honor the tremendous gift, looking at the donors closed eyes.

I think about the neural pathways that allow us to see light, photons traveling all the way through the vitreous humor of our eyes to react with rods and cones, signals traveling across nerves, criss-crossing our brains, sending back out nerve signals to our muscles so we can smile at our loved ones, Kelson said. The gift the donors have given us is not just the ability to see and study the structure of the eye or to know empirically the pathways that allow our brains to see. Donors remind us of the humanity behind those structures, the reason those functions are important, and the ways in which those functions make us human.

In remembering her brother, David Earl Faris, who was one of the donors honored on Wednesday, Franci Neel remembered so many touches of humanity that made her brother exceptional: his love for travel and art, museums and opera, his skills as a chef, his lifelong passion for tennis, as well as an honor roll of educational achievements that included two PhDs.

He taught me to always be curious and step outside the box, Neel said. He was kind and generous, and so enthusiastic to be able to donate his body for such a worthwhile purpose.

That same desire to give guided Donald Bartels decision to donate. His son, Benjamin Bartels, noted that his father was always the person volunteering to organize the Christmas program at church, serve as Sunday School superintendent, and check in on people when they were sick. He donated blood so regularly that he was a member of the 10-gallon club.

He gave what he could, Benjamin Bartels said of his father. This is why he donated his body for the training of medical students. It was the last of what he could give.

Julie Swaney, M.Div., an assistant adjunct professor of internal medicine in the CU School of Medicine, noted that while in the anatomy lab, students were expected to embrace paradox, remaining distant and detached while empathetic and caring, that you remain attentive to detail and aware of the big picture, that you were both scientific and compassionate, that you understand death in order to embrace life, Swaney said. This paradox will follow you in all of your careers, so live it boldly.

For Matthew Sellen, a student in the physical therapy program, an initial desire to maintain emotional and psychological separation between himself and his donor gave way to stepping across that divide and begin seeing the donor for the human he was.

"All of these things are not just anatomical, theyre experiential and to fully understand them we need to see, hear, and understand those experiences. - Matthew Sellen

Before every lab session, Sellen thanked the donor for the opportunity to work with and learn from him, he said. It was necessary to see the person and not just the body that was in front of me. I became more careful, vigilant, and curious in lab sessions, because I felt like this person was counting on me to take in everything I could. It became an entirely new, rare, and exceptional experience. I began to see that lifetime of experiences in his body in the form of scars, tattoos, a pacemaker, a joint replacement, and so much more. All of these things are not just anatomical, theyre experiential and to fully understand them we need to see, hear, and understand those experiences.

Pascoe told the donors family members who were attending the ceremony that their loved ones have and will continue to indirectly impact patient care for so many by guiding students in understanding how the human body is organized.

I hope you leave with a sense of how truly appreciative we are of the gift your loved ones gave, Pascoe said, adding that for the students in attendance you have such encouragement from your donors because they believed in you so much that they made such a significant act of giving something they had been with their entire lifetime.

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Students Honor Those Who Donated Their Bodies for Anatomy Education - University of Colorado Anschutz Medical Campus

Anatomy

Where to watch Greys Anatomy as 16 seasons vanish from Amazon Prime – Manchester Evening News

Fans of the long-running series Greys Anatomy have been cancelling their Amazon Prime subscriptions after the streaming service removed 16 seasons of the popular show.

Viewers of the American medical drama series took to Twitter to share their frustration at being unable to watch the next instalment of the show. One wrote: Goodbye Amazon Prime. So long and thanks for all the Grey's Anatomy. Now that's gone, I'm gone.

Another added: Time to cancel Amazon Prime since they have removed Greys Anatomy. Greys Anatomy has been removed off Amazon Prime, officially cancelling my subscription, wrote another.

READ MORE:Moon Knight review: This could be the best Marvel's best Disney+ outing so far, if you can get past the accent

Many people were part way through watching the show, with one viewer left halfway through season nine, while others asked for an explanation from the global streaming service.

Amazon responded: We understand the frustration regarding Grey's Anatomy not being available to watch on Prime Video, and apologise for the experience. Our selection changes from time to time. We value customer feedback to help us improve and will pass your interest along.

But dedicated Greys Anatomy fans may want to reconsider their subscriptions and hop over to Disney Plus, which is where the show has moved to - with an extra season to binge. There are now 17 seasons and 364 episodes of the show that are available to watch on Disney Plus, meaning viewers could watch one episode a day for an entire year - minus Christmas day.

Theyre not the only shows to be moved over to Disney recently either, with seven seasons of New Girl moving from Netflix, as well as a number of Marvel shows. Daredevil seasons one to three has made the switch to Disney, as well as three seasons of Jessica Jones, Luke Cage seasons one and two, as well as the first two seasons of Iron Fist and a season of Defenders.

You can sign up to Disney Plus from 7.99 a month here.

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Where to watch Greys Anatomy as 16 seasons vanish from Amazon Prime - Manchester Evening News

Anatomy

Naomi Scott Dishes On Her New ‘Bingeable’ Series ‘Anatomy of a Scandal’ – Just Jared

Naomi Scott makes a stylish appearance on Jimmy Kimmel Live on Thursday (April 21) to hype up her new series, Anatomy of a Scandal.

The 28-year-old actress spoke to host Jimmy about the series, calling it bingeable.

Click inside to read more

I play Olivia Litton who is his [the politician's] parliamentary aide and my life is kind of railroaded by an incident that happens in an elevator two weeks after he ends our five-month-long affair, Naomi explained.

She added, Its bingeable. I binge read the scripts. Im so into it.

It really is a great ride and it also, hopefully opens the the door to some conversations as well.

Check out Naomis full appearance below and find out why she got kicked out of a soccer game!

Anatomy of a Scandal is streaming on Netflix now. Watch the trailer here!

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Naomi Scott Dishes On Her New 'Bingeable' Series 'Anatomy of a Scandal' - Just Jared

Anatomy

Greys Anatomy isnt airing tonight (04/21/22), but when will the next new episode premiere? – PennLive

Greys Anatomy is in season 18, but episode 16 wont be airing tonight, Thursday, April 21. Heres why the show isnt airing for now and when the next new episode of the long-running medical drama will air this spring.

Its simple. The show is on hiatus for a few weeks since episode 15 aired on April 7. Instead, Jumanji: The Next Level is on tonight on ABC. Episode 16 will premiere Thursday, May 5 at 9 p.m. EDT on the network.

If youre one of the streaming types, you can sign up for Greys Anatomy via fuboTV and get a 7-day free trial. FuboTVs pricing starts at $64.99 monthly.

You can also catch the show via Hulu Live at 9 p.m. too.

You can also watch previous seasons on Philo for $25 monthly. Also, you can buy episodes of Greys Anatomy on Apple TV, Vudu, Google Play, YouTube, and Amazon Prime Video.

According to Rotten Tomatoes, heres the synopsis of season 18, episode one titled Here Comes the Sun: The Grey Sloan doctors treat a patient who encountered illegal fireworks; Bailey has her sights set on hiring new doctors, but shes having trouble finding viable options; Owen and Teddy attempt to take the next step in their engagement.

In episode two titled Some Kind of Tomorrow, Meredith seeks advice from Amelia; Richard is reenergized as he takes teaching to a new level at the hospital; Winston treats a patient suffering from kidney failure.

In episode three titled Hotter Than Hell, Dr. Addison Forbes Montgomery returns and graces the Grey Sloan halls with her experience and expertise as she attempts to help Richard teach the newest crop of residents; Meredith has a decision to make; Link confides in Teddy.

In episode four titled With a Little Help From My Friends, Richard recruits Meredith and Bailey to help him launch a new program; Addisons patient has complications from a procedure; Jo helps a woman who goes into premature labor.

In episode five titled Bottle Up And Explode, The doctors spring into action after an explosion rocks Seattle, with the incoming trauma hitting close to home; in Minnesota, Meredith and Amelia meet up with a familiar face who assists in their study.

In episode six titled Every Day Is a Holiday (With You), Its Thanksgiving, and while Meredith faces travel complications due to the weather, Nick steps in to help in more ways than one; Richard and Bailey seek out emergency surgeries; Amelia and Link reconnect.

In episode seven titled Today Was A Fairytale, Dr. Hamilton takes his frustrations out on Meredith, so Nick gives her a chance to blow off steam by scrubbing in on a surgery; Link and Jo take their kids to a fairytale theater performance that goes wrong.

In episode eight titled It Came Upon a Midnight Clear, The doctors celebrate the holidays; Hamilton and Meredith prepare for a milestone on their project; Link wants to spend the holiday with Amelia and Scout as a family; Schmitt is faced with a difficult decision during surgery.

In episode nine titled No Time to Die, The Grey Sloan Memorial doctors grapple with the aftermath of the car crash that involved some of their own; Meredith works to save Dr. Hamiltons life; Levi is impacted from his latest loss.

In episode 10 titled Living in a House Divided, Schmitt must face the Morbidity and Mortality conference; Meredith convinces Nick to scrub in on a surgery in Seattle; Jo faces her feelings.

In episode 11 titled Legacy, Meredith, Amelia, and the team prepare for Dr. Hamiltons long-awaited groundbreaking surgery; Bailey receives an unexpected offer; Owens impatience makes him a difficult physical therapy patient, forcing Link to intervene.

In episode 12 titled The Makings of You, Some doctors at a hospital in Seattle -- including several who began their careers at the facility as interns -- try to balance life and work.

In episode 13 titled Put the Squeeze on Me, Richard ponders his surgical abilities; Jo is charmed by her patients brother; Megan makes sure Teddy and Owen talk out their differences; a pet python causes an uproar.

In episode 14 titled Road Trippin, Tensions at Grey Sloan Memorial rise as the effects of the physician shortage begin to show; Meredith struggles to step away from work as she spends a sick day at home with Zola; the hospital receives an unexpected visitor.

In episode 15 titled Put It to the Test, Bailey is on edge when an accreditation council reviews the residency program; Nick returns to Seattle to perform a first-of-its-kind operation with Meredith.

Episode 16 is expected to focus on Merediths decision to move (or not) to Minnesota. Kate Walsh will also return as Dr. Addison Montgomery!

Watch the promo below:

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Greys Anatomy isnt airing tonight (04/21/22), but when will the next new episode premiere? - PennLive