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Cell Isolation Global Market Report 2022: Significant Growth in the Medical and Pharmaceutical Industries Driving Sector – ResearchAndMarkets.com -…

DUBLIN--(BUSINESS WIRE)--The "Cell Isolation Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2022-2027" report has been added to ResearchAndMarkets.com's offering.

The global cell isolation market size reached US$ 10.3 Billion in 2021. Looking forward, the publisher expects the market to reach US$ 24.6 Billion by 2027, exhibiting a CAGR of 15.62% during 2021-2027. Keeping in mind the uncertainties of COVID-19, we are continuously tracking and evaluating the direct as well as the indirect influence of the pandemic on different end use sectors. These insights are included in the report as a major market contributor.

Cell isolation, or separation, refers to the process of identifying and removing one or more specific cells from a heterogeneous mixture of cell population. The targeted cells are identified, isolated and separated according to their type. Some commonly used methods for cell isolation include magnet-activated cell separation, filtration, centrifugation and flow cytometry.

Cell isolation is also used to diagnose diseases, cellular research and therapies by analyzing the ribonucleic acid (RNA) expressions. It aids in minimizing experimental complexity while analyzing the cells and reducing the interference from other cell types within the sample. As a result, it finds extensive application in cancer research, stem cell biology, immunology and neurology.

Cell Isolation Market Trends:

Significant growth in the medical and pharmaceutical industries is one of the key factors creating a positive outlook for the market. Furthermore, increasing emphasis on cell-based research is providing a thrust to the market growth. Researchers actively utilize isolated cells to develop novel cell therapies and cell-based treatments for various chronic medical ailments. Pharmaceutical manufacturers are also widely using cell isolation technologies to improve drug discovery and develop drugs with enhanced efficacies. In line with this, the increasing requirement for personalized medicines is also contributing to the growth of the market.

Additionally, the development of advanced separation tools for proteins, nucleic acids, chromatin and other complex cells for subsequent analysis is also contributing to the growth of the market. Other factors, including extensive research and development (R&D) activities in the field of biotechnology, along with the implementation of favorable government policies, are anticipated to drive the market toward growth.

Key Market Segmentation

Breakup by Technique:

Breakup by Cell Type:

Breakup by Product:

Breakup by Application:

Breakup by End Use:

Breakup by Region:

Key Questions Answered in This Report:

Key Topics Covered:

1 Preface

2 Scope and Methodology

3 Executive Summary

4 Introduction

5 Global Cell Isolation Market

6 Market Breakup by Technique

7 Market Breakup by Cell Type

8 Market Breakup by Product

9 Market Breakup by Application

10 Market Breakup by End Use

11 Market Breakup by Region

12 SWOT Analysis

13 Value Chain Analysis

14 Porters Five Forces Analysis

15 Price Analysis

16 Competitive Landscape

Companies Mentioned

For more information about this report visit https://www.researchandmarkets.com/r/8hx8ne

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Cell Isolation Global Market Report 2022: Significant Growth in the Medical and Pharmaceutical Industries Driving Sector - ResearchAndMarkets.com -...

Researchers find tumor microbiome interactions may identify new approaches for pancreatic cancer treatment – EurekAlert

Investigators from Rutgers Cancer Institute of New Jersey, the states leading cancer center and only National Cancer Institute-Designated Comprehensive Cancer Center, together with RWJBarnabas Health, examined the microbiome of pancreatic tumors and identified particular microorganisms at single cell resolution that are associated with inflammation and with poor survival. According to the researchers, these microorganisms may be new targets for earlier diagnosis or treatment of pancreatic cancer, which is the fourth leading cause of cancer death for both men and women in the United States. The findings are published in the online version of Cancer Cell (10.1016/j.ccell.2022.09.009).

Microbes are living things that are too small to be seen with the naked eye. We have more microbes living in our body than the total number of human cells, and can be found in organs like the pancreas, which at one time was considered microbe-free. Subhajyoti De, PhD, principal investigator at Rutgers Cancer Institute and senior author of the study along with graduate student Bassel Ghaddar, a student in the MD/PhD program at Rutgers Robert Wood Johnson Medical School, began exploring if there are microbes residing in pancreatic tumors, and if they have consequences for cancer progression or treatment. However, studying microbes in tumors is difficult, in part since every patient is different, and because microbial footprints are too subtle to detect reliably.

To explore further, the researchers teamed up with Martin Blaser, MD, Henry Rutgers Chair of the Human Microbiome at Rutgers University and world-renowned microbiome expert. The investigators developed a genomic approach called SAHMI (Single-cell analysis of Host-Microbiome Interactions) to identify microorganisms associated with individual human cells. Sifting through millions of RNA sequences using sophisticated software, they identified which ones likely represent human genes, and which ones are microbial in origin. This new technique allowed us to identify tumor-associated microbes and measure the activity of the host cells at the same time, which is a significant technical advance, and the results were stunning, notes Dr. De, who is also an associate professor of cancer systems biology at Rutgers Robert Wood Johnson Medical School.

Studying two independent groups of pancreatic tumors, the team found that some had bacteria that associated with specific cell-types within the tumor, which were essentially absent in normal pancreatic tissues. These bacteria were predominantly located within tumor cells, and their abundance correlated with cancer-related cell activities. The specific signatures of the microbes that were found predicted particularly aggressive cancer progression and poor prognosis.

The microbial footprints within the pancreatic tumors raised the question of whether the immune cells that were present were responding to the cancer or to the microbes. The study findings suggested that the immune responses were mostly responding to the microbes in the tumor and not to the cancer cells. Our observations provide a new view about why pancreatic cancers are so difficult to treat, notes Dr. Blaser, who is also a research member at Rutgers Cancer Institute and professor of epidemiology and biostatistics at Rutgers School of Public Health. But better understanding these interactions may identify new approaches for therapies.

Along with Drs. De, Ghaddar, and Blaser, other investigators include: Antara Biswas, PhD, Center for Systems and Computational Biology, Rutgers Cancer Institute; Chris Harris, PhD, Department of Surgery, University of Rochester Medical Center; M. Bishr Omary, PhD, Center for Advanced Biotechnology and Medicine, Rutgers University and Darren R. Carpizo, MD, PhD, Department of Surgery, University of Rochester Medical Center.

About Rutgers Cancer Institute of New Jersey

As New Jerseys only National Cancer Institute-designated Comprehensive Cancer Center, Rutgers Cancer Institute, together with RWJBarnabas Health, offers the most advanced cancer treatment options including bone marrow transplantation, proton therapy, CAR T-cell therapy and complex surgical procedures. Along with clinical trials and novel therapeutics such as precision medicine and immunotherapy many of which are not widely available patients have access to these cutting-edge therapies at Rutgers Cancer Institute of New Jersey in New Brunswick, Rutgers Cancer Institute of New Jersey at University Hospital in Newark, as well as through RWJBarnabas Health facilities. To make a tax-deductible gift to support the Cancer Institute of New Jersey, call 848-932-8013 or visitwww.cinj.org/giving.

Observational study

Cells

Tumor microbiome links cellular programs and immunity in pancreatic cancer

10-Oct-2022

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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FDA Approves Furosemide Injection for At-Home Treatment of Congestion in Chronic Heart Failure – MD Magazine

The US Food and Drug Administration (FDA) has approved furosemide injection 80 mg/ 10 mL (FUROSCIX) for the at-home treatment of congestion in patients with chronic heart failure.

Announced on October 10 in a statement from scPharmaceuticals, the approval adds to the armamentarium available for prescribers managing worsening heart failure, a disease that impacts more than 6 million Americans and costs more than $30 billion in care annually.

The first and only self-administered subcutaneous loop diuretic for at-home treatment of congestion in chronic heart failure, the proprietary furosemide solution is administered in subcutaneous doses via a wearable, pre-programmed delivery system, called the On-Body Infusor, placed on the patients body.

This marks a tremendous opportunity to improve the at-home managementofworsening congestion in patients with heart failurewho display reduced responsiveness to oral diureticsand require administration of intravenous diuretics, which typically requires admission tothe hospital, said William T. Abraham, MD, Professor of Internal Medicine, Physiology and Cell Biology at The Ohio State University and scPharmaceuticals Board member, in the aforementioned statement. The FDAs approval of FUROSCIX is significant and will allow patients to be treated outside of the hospital setting, and I look forward to incorporating it into my own practice as quickly as possible.

The furosemide solution targets heart failure-related congestion by reducing fluid overload in adult patients with NYHA Class II and III chronic heart failure who do not require hospitalization but also have not had full response to oral diuretics. As such, it will be available for outpatient use.

Data from the phase 2 AT HOME-HF Pilot studya multicenter, randomized trial assessing subcutaneous furosemide 80 mg/10 mL versus standard care in 51 patients with chronic heart failure with congestion uncontrolled by diuresisshowed a 37% reduced risk of heart failure hospitalization among treated patients compared to standard-care patients at 30 days.

In key secondary endpoints, furosemide was associated with greater reductions in mean patient body weight from baseline to day 3 (2.8 vs 0.8; P = .035), as well as improvements in pulmonary-related metrics including mean 5-item dyspnea score improvement from baseline to day 3 (-0.5 vs 0.1; P = .019).

The data, presented at the Heart Failure Society of America (HFSA) 2022 Annual Meeting in Washington, DC last week, signaled a new opportunity to manage heart failure in pre-hospitalized patients.

This small study points to a possible new way to treat patients with heart failure exacerbation without hospitalization, said Marvin Konstam, MD, professor of medicine at Tufts University School Medicine, said in his AT HOME-HF presentation at HFSA 2022. The AT-HOME HF study, with limited statistical power, generated a directional favorable primary end point which was not statistically significant.

Konstam added the findings support a cohesive message with statistical significance across body weight, dyspnea scores, and functional capacity, with an analogous trend in health-related quality of life.

In their release, scPharmaceuticals noted furosemide injection is not indicated for use in emergency situations or in patients with acute pulmonary edema. Additionally, furosemide injection is contraindicated in patients with anuria, patients with a history of hypersensitivity to furosemide or medical adhesives, and in patients with hepatic cirrhosis or ascites.

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Leaning in to the scientific community – ASBMB Today

Kelly Ward has understood the value of community in the pursuit of science since she was a child. She grew up in Reading, Massachusetts, home to a school system she praises for having great opportunities for young students to be involved in science, technology, engineering and mathematics pursuits.

Ward joined Science Olympiad, a nationwide team-based science competition, in middle school, kept up her involvement all through high school and even went to the national competition.

Courtesy of Kelly Ward

Kelly Ward is a senior at Northeastern University with a biochemistry majorand a data science minor.

I really liked participating in the competitions, and you can see that today given that I went into biochemistry, she said. I love the process of asking a question, designing the experiment, and seeing if youve answered the question. I find it really rewarding.

Ward went on to choose Northeastern University for her undergraduate degree because it has a strong biochemistry program, research opportunities and a co-op program.

An American Society for Biochemistry and Molecular Biology Student Chapter member since the fall of her first year, Ward said she knew she wanted to be involved with the chapter as soon as she saw its thriving booth at the Northeastern student activities fair. Everyone seemed really nice, welcoming, and passionate about their research areas, she said.

After her first year as a member, she became the chapters secretary; she was the president last year and is serving as president again this year.

Embedded in the rich biotechnology ecosystem of Boston, Ward and her chapter have a lot of opportunities for external engagement. Under her leadership and in collaboration with the biochemistry program director, Kirsten Fertuck, the chapter hosts frequent panels with local professionals, focused on career progression and life as an industry scientist.

Weve had speakers from a variety of biotech companies in and around Boston, Ward said. Its been incredibly beneficial to hear about their experiences and gather great advice.

Her chapter also hosts panels with Northeastern faculty about undergraduate research and graduate school. Northeasterns co-op program, where students work full time for six months instead of attending classes, ties nicely into the atmosphere of being embedded in the local scientific community and experiential learning.

Ward thinks its important to keep the social elements of science and community engagement alive too. Her chapter hosts games nights and offers volunteer opportunities. The members partner with other Northeastern clubs as well as clubs at other Boston area colleges to grow their community and network. Her chapter has hosted Active Site, a regional conference for undergraduates sponsored by the ASBMB.

Now a senior with a biochemistry major and a data science minor, Ward wants to go on to graduate school to continue her scientific studies. Shes open to a variety of programs including biochemistry or immunology but ultimately would like to continue to work in oncology.

I have been fascinated by the variety of approaches to cancer treatment that Ive seen during my co-ops and on campus research, she said, and Id love to continue to work in this complex field.

Whatever becomes her ultimate career goal, Ward knows shed like to be in a position where she can mentor younger scientists. Mentoring, she said, has been an important part of her own journey.

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ASBMB weighs in on Title IX updates – ASBMB Today

The American Society for Biochemistry and Molecular Biology last month made five recommendations to the U.S. Department of Education in response to the agencys proposed rulemaking regarding sexual harassment and Title IX protections.

The recommendations included (1) defining sexual harassment better, (2) eliminating the requirement for live cross-examinations in harassment and assault cases, (3) making explicit protections to lesbian, gay, bisexual, transgender, queer or questioning, intersex, asexual, and other non-straight, non-cisgender identifying people, (4) confirming protections against multiple forms of retaliation, and (5) making explicit protections of all postdocs.

Title IX is a 1972 civil rights law that protects people from discrimination based on sex in educational institutions, programs or activities that receive federal funding. Over the decades, the law has opened doors for many women and girls to have equal access to education and extracurricular activities, such as sports. But in recent years, Title IX protections have come and gone, depending upon who has been in the White House.

In 2011, the Obama administration provided a guidance urging colleges and universities to deal with sexual harassment and assaults on campus. However, the Trump administration removed many protections. Then-Secretary of Education Betsy DeVos, for example, narrowed the definition of sexual harassment and stripped away protections in favor the accused, resulting in damaging experiences for survivors, such as mandatory live cross-examinations.

In the first month President Joe Biden was in office, he issued an executive order aimed at preventing and combating discrimination on the basis of gender identity and sexual orientation in the federal service. Two months later, he issued an executive order on discrimination specifically in educational settings.

That summer, the ASBMB urged the Department of Education Office of Civil Rights to clearly define sexual harassment, eliminate mandatory live cross-examinations and change the standard of evidence in Title IX cases to align with other civil cases by using a preponderance of the evidence.

This summer, the agency released a notice of proposed rulemaking, to which the ASBMB responded with the following suggestions, hewing closely to the ones it released in June 2021.

The society expressed support for the agencys new definition of sexual harassment: sex discrimination, including related to a hostile environment under the recipients education program or activity, as well as discrimination on the basis of sex stereotypes, sex characteristics, pregnancy or related conditions, sexual orientation and gender identity.

Whereas the Trump administrations definition had three categories sexual assault, quid pro quo and sexual harassment the new definition ensures that all forms of sexual harassment and sexual violence are covered.

The society expressed support for the agencys new language making live cross-examinations of harassment and assault survivors optional. The society also urged officials to allow institutions to proceed with the single-investigator model when needed as it is better for avoiding direct confrontation between the accuser and the accused, and it is common practice in civil rights cases.

The society expressed support for proposed language making LGBTQIA+ individuals explicitly protected under Title IX. By protecting LGBTQIA+ students, the department will be creating safer and less hostile learning environments not only for LGBTQIA+ students but for all students, resulting in more optimal learning outcomes, the society wrote.

The society expressed support for a proposed amendment that would protect survivors of harassment and assault from multiple forms of retaliation, not just retaliation from supervisors. While keeping language broad so that multiple situations can apply is beneficial, the society wrote, explaining different forms of retaliation is key to upholding communication between the department and those protected by Title IX. Moreover, updating Title IX to specifically state the prohibition of peer retaliation is important to ensure more victims feel safe to come forward.

The society urged the agency to explicitly extend protections to people in postdoctoral positions. Currently, students, employees and people participating or attempting to participate in an education program or activity can file Title IX grievances; however, there is no specific wording to protect postdocs, who sometimes are not classified as employees. The society recommended the agency insert direct language to all amendments, including those that prohibit discrimination against pregnant people, to protect individuals in postdoctoral positions.

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Cook recognized for scientific leadership in biohealth research – University of WisconsinMilwaukee

James Cook, distinguished professor in the Department of Chemistry & Biochemistry at the University of Wisconsin-Milwaukee, has been awarded the Hector F. DeLuca Scientific Achievement Award from BioForward Wisconsin. The award recognizes Cooks scientific leadership and contributions to the states biohealth industry.

Cook is a leading expert in GABA-A brain receptor drug targeting and has published more than 550 papers in the fields of natural products, medicinal chemistry and organic synthesis. He is a recipient of the UW System Innovator Award and the UW-Milwaukee Innovator Award, and he has filed over 90 patents.

Cooks UWM research group created a series of compounds for drug-resistant epilepsy and chronic pain that were licensed to RespireRx Pharmaceuticals. The compounds carry no risk of addiction, tolerance, sedation or impaired coordination in preclinical tests of their use to circumvent the opioid crisis.

His research collaboration at the Centre for Addiction and Mental Health at the University of Toronto has led to licensing compounds that target depression, schizophrenia and Alzheimers disease to Damona Pharmaceuticals.

He cofounded four pharmaceutical startups, including Promentis Pharmaceuticals with David Baker at Marquette University. Promentis has a drug in clinical trials for the chronic mental illness trichotillomania (chronic hair-pulling). The compound also is effective for treating anxiety disorder without the side effects of sedation or dependence.

With neurologist Soma Sengupta at the University of Cincinnati, Cook cofounded Amlal Pharmaceuticals, which is testing compounds for glioblastoma (brain tumors), melanoma and non-small cell lung cancer.

At UWM, Cook was a founding member of the Milwaukee Institute for Drug Discovery, which has faculty and student members from the departments of chemistry and biochemistry, psychology, biological sciences and engineering.

Interacting with various departments, students and over 30 collaborators worldwide have made it much easier to do drug discovery and development at UWM, Cook said. The support from the UWM administration and the faculty and staff of the MIDD has been unwavering, even when resources were scarce. This has led to a bright future for MIDD and UWM.

Cook joined the UWM faculty in 1973 and was promoted to university distinguished professor in 2002.

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Cook recognized for scientific leadership in biohealth research - University of WisconsinMilwaukee

Houghton Hall dedication to highlight homecoming at Fredonia – Evening Observer

Submitted PhotoA re-imagined and renovated collaborative student space in Houghton Hall.

The welcome mat will be rolled out during homecoming, including on Friday for the dedication of the renovated and redesigned Houghton Hall that completes the transformation of STEM education at the State University of New York at Fredonia.

Houghton Hall brings Geology and Environmental Sciences; Physics, Computer and Information Sciences, and Mathematical Sciences together under one roof and connects with the Science Center home to biology, biochemistry, chemistry and science education to form the Fredonia Science Complex.

Houghton is equipped with high-tech laboratories with cutting-edge equipment for teaching and research, well-designed conference rooms and comfortable student lounges that encourage interdisciplinary collaboration.

One only has to stroll through Houghton to appreciate its impact on our students and their professors, said Dean of the College of Liberal Arts and Sciences Andy Karafa. The energy is palpable.

Houghton Project Shepherd and Associate Professor of Physics Erica Simoson will lead a tour of the building that starts in the front first floor lobby at 1 p.m. The dedication ceremony, at 2 p.m., will feature remarks by Fredonia President Stephen H. Kolison Jr. and Dean Karafa.

The formal ribbon-cutting ceremony is at 2:30 p.m., followed by individual ribbon-cutting ceremonies of 13 named spaces beginning at 3 p.m.

Faculty and students will be stationed in their respective academic departments and areas of interest, such as the Department of Mathematical Sciences unique fishbowl study room and the Department of Computer and Information Sciences robotics lab, throughout the afternoon. Light refreshments will be served at 4:30 p.m.

One guiding principle behind the design of the building was collaborative learning. Indeed, one of our spaces is called the Bradley Collaboratory. Just about everywhere you walk, you see students engaging with each other and with their professors, Karafa said.

Renovation of the 74,000-square-foot structure that opened in the 1970s can easily be described as massive, encompassing interior demolition, hazardous materials abatement and exterior rehabilitation that began in 2017, followed by interior redesign, construction and fit-out, or finish work in individual spaces. Houghton began to resemble a parking ramp when exterior brick and concrete block outer walls were removed early in the demolition phase.

The finished building incorporates many new features, such as brightly painted interiors, an additional interior corridor on the first and second floors that leads to department office suites, as well as open study areas lit by natural light and interior research labs that can be viewed from corridors. Yet, some of Houghtons character dark brick walls in stairwells, skylights and precast concrete t-shaped beams in ceilings remains.

When you walk through the building, theres still a sense of what Houghton used to be, but at the same time theres a newness about it, observed Director of Facilities Planning Markus Kessler. Its a much more pleasant space to be in for faculty and students.

As the Houghton project spanned eight years, from initial planning to completion, there were two project shepherds. Department of Chemistry and Biochemistry Associate Professor Emeritus Holly Lawson served as the original project shepherd until she retired, and was succeeded by Dr. Simoson. Both worked diligently to ensure that the needs of faculty and students were communicated and met.

The research and teaching labs were carefully designed with a great deal of faculty input to facilitate the teacher-scholar model, where members of the faculty closely mentor students in a wide array of research activities, Karafa said. Fredonia professors have always engaged students in such high-impact experiences, he added.

Members of the Houghton Dedication Committee include Simoson, Director of Facilities Services Kevin Cloos, Director of Marketing and Communications Jeff Woodard, Capital Projects Manager Ken Schmitz, Director of Development June Miller-Spann of the Fredonia College Foundation, Karafa and Mr. Kessler.

Campus representatives serving on the Houghton Planning Committee included Mr. Schmitz, former Capital Projects Manager Paul Agle, Simoson, Kessler and Dr. Lawson, along with representatives of the SUNY Construction Fund and Mitchell Giurgola, project architect.

Assisting the planning committee were Gretchen Fronczak from Facilities Planning, Interim Vice President for University Advancement Betty Gossett, Assistant Director of Facilities-Custodial Services Mark Delcamp, Vice President for Finance and Administration Michael Metzger, Director of Purchasing Shari Miller and Karafa.

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EVJ Lifts the Lid on the Relationship Between Human Behavior and Equine Welfare – Equi Management

Understanding what drives human behavior is at the heart of horse health, but studies in this area have been lacking in equine veterinary science. The Equine Veterinary Journal (EVJ) aims to address the shortfall with a special virtual collection of 20 articles on understanding owner behaviors and motivation. The collection is free to viewherefor 12 weeks and marks the collections guest editor David Rendles appointment as president of BEVA.

Research in equine veterinary science has hitherto focused primarily on the information needed to prevent and cure disease, with little attention paid to the attitudes and actions of horse owners, veterinary surgeons, and numerous other professionals to implementing science-based advice. This virtual issue, guest edited by David Rendle and Tamzin Furtado, brings together 20 thought-provoking papers highlighting work performed around equine stakeholder knowledge, attitudes and values.

Behavioral studies are important in understanding health-related behaviors and in identifying potential barriers to change, said David Rendle. Failure to utilise behavioral science not only compromises the potential benefits of interventions but can result in overtly negative impacts on health.

Models suggest that in order to change behavior, we first need to understand that behavior and endeavour to understand the attitudes and values which contribute to the behavior being performed, as well as the social and environmental factors which make the behavior easier or more difficult to carry out.

This special EVJ collection showcasesstudies that seek to understand horse owner behavior around their horses health, supplementing clinical evidence with information about the real-life behaviors of equine owners and professionals and the factors that influence them.

It includes papers on horse owner knowledge and opinions on recognizing colic, treating infectious disease, uptake of some of the most basic preventive health measures such as vaccination and deworming as well as attitudes and behavior around equine obesity and laminitis. Other studies highlight the importance of professionals other than vets such as farriers, equine podiatrists, physiotherapists, dental technicians, chiropractors, and equestrian organizations such as the British Horse Society.

As our understanding of the drivers of behavior develops, pre-existing behavior change models will help us to understand the barriers and enablers to uptake, said Tamzin Furtado. With dissemination of this knowledge, we have a better chance of communicating effectively and implementing change that will have a positive impact on equine welfare at individual, community, and national level.

This collection is both compelling and eye-opening, said Professor Celia Marr, Editor of the EVJ. It is dangerous to assume an understanding of the motivators of horse owner behaviors and actions; these papers confirm the current lack of comprehension, providing an invaluable insight, which will ultimately help us to accelerate improvements in equine veterinary practice and, most importantly, equine welfare.

The virtual issue can be found athttps://beva.onlinelibrary.wiley.com/doi/toc/10.1001/(ISSN)2042-3306.owner-behavioursand will be free to view until 26 December 2022.

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Addressing the Question of Becoming Evil: Dr. James Waller lectures at the William and Mary School of Law | Flat Hat News – The Flat Hat

Wednesday, Oct. 5, the William and Mary School of Law hosted Dr. James Waller, professor of Holocaust and Genocide Studies at Keene State College and the director of academic programs with the Auschwitz Institute for the Prevention of Genocide and Mass Atrocities. Waller is a widely published author of six books, most notably his award winning Becoming Evil: How Ordinary People Commit Genocide and Mass Killing and Confronting Evil: Engaging Our Responsibility to Prevent Genocide.

Waller is also the curriculum developer and lead instructor for the Raphael Lemkin seminars on genocide prevention at the Auschwitz Institute. The Raphael Lemkin seminars have trained over 5000 governmental officials and security systems officials all over the world.

Waller has lectured at multiple universities and institutions, including the Center for Judaic, Holocaust and Peace Studies at the Appalachian State University, which hosted a discussion in commemoration of the liberation of Auschwitz by a division of the Red Armys First Ukranian Front in January of 1945.

Prof. Waller widely researches, teaches and consults for memorials, research centers, universities, government, and non-governmental institutions around the world, the Center said in an online description.

Waller was introduced by Dr. Nancy Combs a Robert E. and Elizabeth S. Scott research professor, Ernest W. Goodrich professor of law and director of the Human Security Law Center.

This is the inaugural Human Security Law Center event, and I suspect it is the inaugural Criminal Law Society event for this year. In any event, we are very happy to partner with the Criminal Law Society and Im very grateful to the student board, to both groups, for all the assistance theyve provided in bringing your speaker today, who is Dr. James Waller, Combs said.

Waller began his lecture by prompting attendants to shift their lens of focus from a legal perspective to a psychological one in order to address the lectures central question: How is it that ordinary people come to commit genocide and mass atrocity?

To do that, Im well aware that most everyone in this room is coming to this with a legal lens, and I need you to turn that off for the next 45 minutes, Waller said. You can turn it back on when class starts. But I need you to join me in thinking about this through a psychological lens. I am a trained social psychologist whose interests over 30 years have skewed towards psychology of large scale mass violence, typically in genocide, war crimes and crimes against humanity.

Waller then showed attendants a brief video with no sound that was from Liepja, Latvia in 1941-42 and explained the contextual history behind it.

In 1941 to 42, as the Holocaust was unfolding throughout the east, German armies went through these territories, Waller said. They conquered villages, towns and cities, and behind them came one of four groups, operational units called Einsatzgruppen. The Einsatzgruppens job was to round up all the opponents in the village, mostly Jews, but also Communists, people they suspected were not being sympathy to Nazi practices, to round them up and tell them that they were being transported elsewhere for their own safety and security, only to find out that the transportation was just a couple of kilometers outside of town, to a ditch, to a ravine, to a grave that had been dug the night before.

The execution of individuals in this face-to-face manner claimed the lives of over 1.25 million, most of which were Jewish, prior to the construction and opening of any of the death camps in the East. There is a significant amount of photographic evidence of these executions, as well as one video that was filmed during one such round of executions and shown during Wallers lecture.

On this day of Yom Kippur, which is holiest day in the Jewish tradition, we remember the 6 million Jews who werent lost, who were killed in the Holocaust, who werent misplaced, they were actively killed, Waller said. And here, we remember 1.25-1.5 million who were killed in this way, this face-to-face, very intimate way of killing.

Waller then asked what questions a psychologist might ask when watching a clip of such an atrocity and explained that as a psychologist, the discussion ranges from the human behaviors of victims, rescuers, bystanders and perpetrators.

Were also talking about the behavior of perpetrators, Waller said. How did the perpetrators come to understand that what theyre doing in their mindset is the right thing to do? To not do it would be the wrong thing to do. What are they thinking? How are they justifying their own actions?

In the past 30 years, Waller has been working to answer questions such as this. Waller began teaching in Berlin, Germany, and worked with archival material like videos, photographs, trial and interrogation testimonies and bystander accounts and perpetrator accounts. Due to the psychological aspect of his work, Waller was inclined to begin conducting his own interviews in order to gain further insight into the thoughts and experiences of perpetrators, as well as survivors, witnesses and bystanders.

Waller has done face-to-face interviews with over 225 alleged or convicted perpetrators of genocide, war crimes and crimes against humanity in areas throughout Latin America, Africa and Bosnia-Herzegovinia.

When I do those interviews, I also take the time to speak with survivors, witnesses and bystanders, because I want to hear from them How do you think someone came to commit these types of atrocities? because many times the people who committed the atrocities are people they knew, Waller said.

When addressing the question of the mindset of a perpetrator, Waller told the story of interviewing a perpetrator of the massacre of over 5000 individuals at the Nyamata Parish Catholic Church in Ntarama outside of the capital city of Kigali during the Rwandan genocide.

The first time I visited Rwanda was four years after the genocide and at most of the churches, the bodies just laid where they had fallen, Waller said. Today, Rwanda has reclaimed most of those physical remains and theyve left the clothing here, displayed in various ways, throughout these places of memory.

Most of those killed in the massacre were children and women. The church was converted to a memorial in April of 1997 and now houses many articles of clothing of victims, as well as execution instruments and skeletal remains.

I was back in Rwanda, in a prison, interviewing a perpetrator and I didnt get his charge sheet before he came out, Waller said. We started the interview cold, and a couple minutes into it he said something that triggered something for me in memory. A couple minutes later, I knew exactly what it was, just by coincidence. I was interviewing the person who was responsible for organizing this massacre in Ntarama.

During this discussion, Waller asked attendants to describe what they believed the perpetrator to be, both physically and intellectually. Attendants described the imagined perpetrators as young and fairly intelligent, though Waller noted that most people would imagine a perpetrator to be far from ordinary.

Waller told attendants that this particular perpetrator was from Ntarama and that the massacre occurred where he had grown up. He had been a member at the church and was the equivalent of a grade school teacher in the village.

When we asked him the question, How did you come to do this? He just kept repeating in Kinyarwanda, Ive lost myself. I did not know who I was. I lost myself. I did not know who I was, Waller said. And that very well is a coping mechanism for him. But as a psychologist, it also testifies to the fact that he made a series of choices here, that there was a transformation in him, that he could probably honestly say he lost himself. He could never have pictured himself doing this.

Wallers commitment to investigating the psychology of the perpetrators extends into his work with government policy makers to prevent mass violence.

This is the danger, Waller said. We absolutely want to understand this. I want to understand it because the work I do with government policy makers is about prevention. If we dont understand how the people come to commit these crimes, how can we work with policymakers to help them understand the ways we can unpack prevention to prevent this type of activity from happening?

In Wallers line of work, examining the psychology behind perpetrator behavior involves acknowledging that there is a strict difference between understanding the behavior and excusing the behavior.

Sometimes, I come really close to this line of excusing, forgiving, apologizing for, and its never at all what Ive meant to do with this work, nor do any of us who work in perpetrator behavior, thats not what were trying to do. Understanding is completely different from excusing and apologizing is certainly different from forgiving the behavior.

Sometimes, I come really close to this line of excusing, forgiving, apologizing for, and its never at all what Ive meant to do with this work, nor do any of us who work in perpetrator behavior, thats not what were trying to do, Waller said. Understanding is completely different from excusing and apologizing is certainly different from forgiving the behavior.

The work of psychologists like Waller in relation to the investigation of perpetrator behavior involves the psychological phenomena of understanding the complexity of cognitive dissonance.

What theyve done is so horrendous that psychologists will tell us that people cant live with the cognitive dissonance of, Ive killed 60 people but I still think Im a good person, Waller said. They have to somehow reduce and reconcile that dissonance. And they have to develop lies that they tell themselves So I want to understand what lies they told themselves.

Waller closed the discussion by acknowledging prior work done in psychology to address the causes behind the behavior of perpetrators, addressing studies of IQ and the Rorschach testing done at the Nuremberg trials conducted under psychiatrist Douglas M. Kelley and psychologist Gustave Gilbert. When studying the intelligence levels of perpetrators, Waller points out that the public generally expects a lower IQ.

If its low intelligence, most importantly, we can fix low intelligence, Waller said. Thats what education is for. Thats what school is for. So thats what were hoping to see. What do we see? We see that these men at Nuremberg were very bright. They were above average intelligence, 110, 120. Some at the genius level, 130 to 140. So it wasnt intelligence that was an issue. So if its not low intelligence, then maybe it is pathology, some type of mental or emotional disorder. Our test for that was the Rorschach test.

The Rorschach test is a pathological test conducted using a series of 10 ink blots that are purposefully ambiguous. A person trained in Rorschach methodology can read into an individuals responses and particular insecurities projected into responses. Perpetrators at the Nuremberg trial, all with one exception being Julius Streicher, tested mentally healthy in terms of the Rorschach test.

If you see an extraordinary behavior, you assume an extraordinary cause. And very simply, what Im asking you to do is separate those two. Can we see something extraordinary evil and say it has ordinary causes to it?

If you see an extraordinary behavior, you assume an extraordinary cause, Waller said. And very simply, what Im asking you to do is separate those two. Can we see something extraordinary evil and say it has ordinary causes to it?

After working to grapple with these issues for many years, Waller has been met with many questions about what it means to sit down with individuals and garner impressions of those who have committed mass atrocities. He told attendants that he has previously been asked what it is like to sit down with such perpetrators.

I know what theyre getting at, that there is something like a television show where theyre stuck with someone, and evil kind of radiates from them, Waller said. I just have never had that experience. I mean, everyone Ive sat with has had that spark of ordinariness to them These are people who have made decisions over a period of time, who have undergone changes, who have used their agency in ways that are terribly destructive. And what Ive wanted to figure out is, How does this happen? If ordinary people do it, how does it occur?

Waller told attendants that evil does not brew in an individual overnight. The perpetrators he has interviewed have described a sense of escalating commitments to killing, thus leading to their eventual transformation. When addressing perpetrator behavior, Waller considers the cultural construction of worldview in terms of group-based identity, authority orientation, and social dominance. Additionally, he addresses the psychological construction of the other and the question of moral orientation and the social construction of cruelty.

When asked about his work in the realm of the prevention of mass atrocities, Waller informed attendants of his work at the Auschwitz Institute, which has involved the education of over 9000 government policy makers and security specter personnel in over 92 countries around the globe. The discussion that is given is meant to remove, particularly from Western countries, the sense of, This could never happen here.

Part of what were pushing to them is to say, if you understand the ordinariness of the people who commit this, and if you understand that no country is immune to it, then genocide prevention is also domestic policy issue, not simply foreign policy, Waller said.

The rest is here:
Addressing the Question of Becoming Evil: Dr. James Waller lectures at the William and Mary School of Law | Flat Hat News - The Flat Hat

Ovulation linked to heightened competitiveness in women — except among those using hormonal contraceptives – PsyPost

Self-development-oriented competitiveness fluctuates across the menstrual cycle, according to new research published in Adaptive Human Behavior and Physiology. But hormonal contraceptives appear to interfere with this effect.

Ive always been really interested in what drives behaviour but, over time, I have been more and more interested in the relationship between the brain and our biology, said study author Lindsie Catherine Arthur, a PhD candidate at The University of Melbourne.

Hormones play an important role in lots of biological processes, like growth and development or sexual function. There are lots of ways that hormones are thought to influence behaviour, but empirical research is still catching up. Its those things that I am interested in understanding.

The researchers recruited 278 women (average age 26) from 21 different countries. Eight-six participants were hormonal contraception users, while the other 192 women were not. The participants completed a brief prescreening and baseline survey to collect demographic and menstrual cycle characteristics, followed by 28-days of daily surveys.

Competitiveness was measured using a scientifically-validated questionnaire known as the Multidimensional Competitive Orientation Inventory, which assesses four different types of competitive tendencies: hypercompetitive orientation, self-developmental competitive orientation, anxiety-driven competition avoidance, and lack of interest toward competition.

The researchers found that naturally-cycling women experienced a mid-cycle increase in self-development competitiveness. But this was not observed among women using hormonal contraception. People with a high level of self-development competitiveness agree with statements such as Competitive situations allow me to bring the best out of myself, I enjoy testing myself in competitive situations, and I enjoy competition as it allows me to discover my abilities.

The findings indicate that competitive motivation fluctuates across the menstrual cycle, with periods of high fertility associated with higher competitiveness, Arthur told PsyPost. However, hormonal contraceptives disrupt the natural cycle and blunt the expected peak in competitiveness that is observed around ovulation. Importantly, this study does not say that hormonal contraceptive users are less competitive than naturally cycling women overall.

But as with any study, the new research includes some caveats.

This research used self-report measures and didnt look directly at behaviour, instead we asked women how much they enjoyed competitive situations or how much they wanted to beat other people. We are now looking at a range of behaviours that research tells us women use to compete. For example, we are measuring things like appearance enhancement and gossip, which can be used to compete with others.

The study, Fertility predicts self-development-oriented competitiveness in naturally cycling women but not hormonal contraceptive users, was authored by Lindsie C. Arthur and Khandis R. Blake.

Link:
Ovulation linked to heightened competitiveness in women -- except among those using hormonal contraceptives - PsyPost