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Anatomy

Anatomy Of A Biopharma VC Deal – BioProcess Online

By Matthew Pillar, Editor, Bioprocess Online

This article originally appeared in Life Science Leader magazine

From my perch in the Business of Biotech podcast studio, Ive interviewed quite a few biopharma leaders whose careers were inspired by very personal experiences with disease.

Ray Therapeutics CEO Paul Bresge is one such leader. Until 2010, leading a biotech wasnt on his radar. Hed built a long and successful career as a leader in unrelated industries - industrial tools and a courier service, for example. Then, his 15-year-old daughter was diagnosed with retinitis pigmentosa (RP), a rare genetic disease that causes degradation of retinal cells over time. She was going blind. Ophthalmologists told him there was nothing that could be done to save his daughters vision.

Paul Bresge, CEO, Ray TherapeuticsThats when Bresge threw himself, and his money, behind the work of Drs. Henry Klassen and Jing Yang, helping to form jCyte, a cell therapy company with a late-stage candidate for RP. He served as the companys advisory board chair for five years before becoming its CEO in 2016. In July 2021, on the heels of jCytes licensing and commercialization deal with Santen Pharmaceutical, Bresge made another move in his effort to explore and advance the therapeutic options for RP. He cofounded Ray Therapeutics, a preclinical company pursuing RP with a promising new genotype-agnostic approach called optogenetics that shows promise of restoring vision in RP patients, not just halting the degradation of retinal cells.

FUNDING FOLLOWS SCIENCE, NOT MISSION STATEMENTS

Dmitry Kuzmin, Ph.D., co-founder and managing partner, 4BIO CapitalObviously, a first priority in Bresges new role as CEO of a biopharma startup was raising money. Less obvious is that mission-driven leaders like Bresge, pushed forward by the personal experiences theyve had with the diseases they choose to attack, are subject to a bit more scrutiny from the VC world than scientific founders typically are. Thats a reality Dmitri Dima Kuzmin, Ph.D., managing partner at 4BIO Capital, readily admits on episode 119 of the Business of Biotech podcast.

To me, a CEO with a personal story is always a risk, 100 percent, says Kuzmin. We are not a charity; we are a venture capital firm. That means we have to make a return on investment for partners, and thats what moves these therapies forward. As such, he says vetting the person at the helm is as important as vetting the startups scientific data. We have to be certain he will make the right business decisions to ensure that we get there.

Kuzmin has seen the inspiration-driven stories before. Many of them end poorly for all parties. There are other companies in the biopharma space that have been built by the parents of children carrying the disease. Unfortunately, as we know, not all of them have been successful.

Still, heading into 2021, 4BIO led a $6 million seed round to get Ray Therapeutics on its feet. Kuzmin says his firm pondered two key questions in the due diligence process leading up to that decision.

The first, says Kuzmin, centers on generational improvement in the specific therapeutic modality. How far has the field moved on from the first generation, and what can we count on? he asks.

The second consideration 4BIO dwells on is the companys management team, and that starts with the CEO. We spend a lot of time making sure the leader of the company and the people theyre putting around them are the best people to take the science forward, says Kuzmin.

On the former consideration, Kuzmin leaned into his own academic background, and his experience in the retinal disease space. He earned his Ph.D. in neurochemistry, his MSc in experimental therapeutics, did his doctoral fellowship at Max Planck and his postdoc at UCL, and holds an experimental therapeutics assistant professorship at Yale, among other accolades. Hes adept at discerning winning science, and he says the current generation of optogenetics is capable of solving all the major limitations seen in the first.

On the second, his analysis of Bresges tenure at jCyte and its successful journey to Phase 3 and ensuing deal with Santen played into the decision. Pauls exposure to the patient organizations, his personal story, and the people he attracts to the effort all supported our decision, says Kuzmin.

VC DEALS ARE A TWO-WAY STREET

Of course, theres a lot more due diligence on the VCs part that goes into funding a new company considerations like the feasibility of clinical trials, the work or lack thereof thats gone into the protection of intellectual property, and the vision for an endgame, whether thats acquisition, commercialization, or some creative path to one or the other. Kuzmin thoroughly covers those bases in a refreshingly transparent way on episode 119. Equally important, but far less often discussed, is the new ventures perspective on what makes a good VC partner.

In this case, 4BIO checked several early boxes for Ray Therapeutics. For starters, the firm is explicitly focused on advanced therapy medicinal products. It doesnt fund small molecules. It doesnt fund antibodies. It only funds novel advanced therapeutic endeavors, most of them cell and gene therapies. Bresge says 4BIOs experience in the advanced retinal therapeutics space, and specifically, Kuzmins depth of optogenetics knowledge, solidified the match. It was very important to me upon leaving jCyte that I continue my mission for patients with blinding diseases, says Bresge. I did my own due diligence prior to the launch of Ray Therapeutics, and the questions 4BIO asked of the science and the market mirrored those I asked at the time. For Bresge, that was the first indication that 4BIO had more than financing to offer. Once I had an introduction to Dima, I knew 4BIO was absolutely the right investor for us, he says. The chemistry and alignment were there, and in terms of board composition, Dimas unique expertise in optogenetics made his choice a no-brainer.

As for Bresges daughter, her name is Tamar. Shes an artist, writer, and MFA candidate at the School of the Museum of Fine Arts at Tufts University, where shell be teaching next year. She recently gave an incredibly introspective and beautiful TED talk. Look it up on YouTube. Her vision is slowly waning, or precarious, as she puts it in her talk. But her dad, supported by Kuzmin and a dedicated team at Ray Therapeutics, is working on that.

Tune in to episode 119 of the Business of Biotech podcast for a much deeper look into the relationship between a brand-new biopharma and its primary investor.

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Anatomy Of A Biopharma VC Deal - BioProcess Online

Anatomy

Gavan Reilly: Anatomy of silence: why we couldnt talk about Collins – Meath Chronicle

Published: Wed 26 Apr 2023, 8:00 AM

Suffice to say, its been an interesting few days. Lets start at the very beginning.

I was driving to Belfast last Wednesday for the final day of the big Good Friday Agreement commemorations when I got a text from someone involved in the news website The Ditch. I half-knew the sender from previous interactions where wed ended up discussing some of the nuances of their reporting. Having been the ones to end the ministerial careers of Robert Troy and Damien English, their stuff is always well researched and worthy of attention.

The message was a heads-up about an article coming later that day. The junior minister Niall Collins had participated in county council business in 2007 at a time when the council sold off public land, which ended up being bought by Collins own wife. If this amounted to a legally prohibited conflict of interest, there could be jail time.

Right, I said to myself, as Apple CarPlay read me the message somewhere around Castleblayney. Thats something to look out for later. In truth, though, the distractions of the day job kept the curiosity at bay. There was Ursula von der Leyen, and Charles Michel, and Bill Clinton, and Leo Varadkar, and Rishi Sunak all to be listened to for the afternoon, and a cameraman to work alongside, and my part of a podcast to record, and a news bulletin to fill, and a phone with a battery that gave way before the days work was done. I was late getting home.

So when the dust settles and you get a chance to properly read and dwell on the story, your journalist brain kicks in: where has this come from? How do I stand this up for myself? How do I move this on? And thats where the trouble starts. The article says it would be illegal to participate in a vote in which he, or a connected party, had a clear financial interest. But, in this instance, did he actually have one? Yes, his wife had inquired about buying the land but could you conclusively say she materially benefited from a decision simply to put the land on the market? And was that decision the final word? Would there have been another vote to approve the final transaction, later down the line? Is that the one where conflicts of interest come in? Are the minutes available somewhere?

And will Niall Collins talk? Apparently not. There had been no comment to any other outlet by Friday and when I asked my radio producer to approach him about coming on Newstalk on Sunday, there was no reply. Nor was there any luck in tracking down the minutes: the old county councils website had not been archived in any corner of the internet, and the new combined council didnt have them readily to hand.

So what do you do in the meantime? Can you stand up the story for yourself? Not without firsthand access to the documents. Can you say for certain that its not defamatory? Not for certain not to the degree that youd be comfortable repeating on the TV news. But, can you definitively deconstruct it, or point to a material failing in it? No - the authors have documents you dont, and are prepared to cite them. And dont forget: this is an outlet that does its homework, and has the scalps to prove it.

So, what can you do in the meantime? Actually, not very much. Publicly picking holes in the story could easily be an unfair smear on the professional reputation of people who have earned their stripes. But repeating the story as gospel, with no firsthand proof of your own, means you may be baselessly accusing a man of an offence he didnt commit. And all parties involved are still entitled to their good name. Damned if you do, damned if you dont.

Ironically, under Irish law, if you think something might be defamatory, you cant even point people in its direction without compounding the problem. So imagine if the Meath Chronicle went rogue and published a piece accusing its Leinster House columnist of animal cruelty. Youd struggle to find the evidence, because there isnt any: I havent had a pet since I was three. You, as a reader, might feel entitled to take the piece at face value but another news outlet, without any evidence of me kicking a cat or starving a dog, cant simply repeat it as gospel because theyd be repeating a defamation. I could sue not just the Chronicle for its wrongful reporting, but I could sue any other news outlet that carried it as fact.

So youre goosed. Youre lodged in a stalemate where even acknowledging the story, let alone repeating it, is a legal tightrope. Collins knew it, which is probably why he didnt address any media queries - any comment would be reportable and justify further ventilation of the story. And all the while, your Twitter mentions are bombarded by people who gave due credence to the original story and who wonder if theres some kind of conspiracy to suppress a controversy and protect a politically indispensable minister of state (no, really).

Only the veil of parliamentary privilege might give us some ability to repeat the actual allegations - would a TD try to raise it in the chamber? As it happened, yes: Paul Murphy confirmed to Virgin Media News that he was going to seek Dil time for an address from Collins. We could at least report that and lo and behold, given the story a public platform then prompted Collins to issue an on-the-record statement a few hours later.

And from there, game on.

Published: Wed 26 Apr 2023, 8:00 AM

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Gavan Reilly: Anatomy of silence: why we couldnt talk about Collins - Meath Chronicle

Anatomy

The Anatomy of the Hiking Snack – Paste Magazine

Ive always admired the hikers who wake up before the sun does, who drive two hours away to tackle a steep mountain with an incredible view at the top, who see the whole ordeal as an alternative to the gym. I have never been one of those hikers. To me, hiking isnt a form of exercise; its more about being outside, spending time with friends or with myself, allowing my normal life to drop away for a few hours so I can pretend we as a species never left the forest or created the stock market.

If youre the first kind of hiker, all you have to do is pack a few Clif bars in your backpack, and youre ready to go. But if you hike like I do, the food situation is a little more complicated. Packing the right hiking snack requires intuition, forethought and creativity. It demands an appreciation of nature and an understanding of how to curate the best trail mix combos. Most importantly, it takes advanced sandwich-making skills.

The following is a guide for us, the hikers who are more concerned about what theyre going to eat at the summit than actually making it up the mountain. This is the anatomy of the hiking snack.

The hike snack technically begins before youre even on the trail. Caffeine, especially for an early morning hike, is essential. Theres nothing like the feeling of embarking on the first leg of a seven-mile trail with espresso coursing through your veins, making you delusional enough to imagine you can manage the hike without nursing your sore muscles for days afterward. I prefer coffee, but feel free to choose your favorite caffeine-delivery system. Make it ahead of time and put it in a thermos, or stop by a local coffee shop before you begin your trek.

There is one part of the hiking snack that you absolutely cannot forget under any circumstances: water. You need a lot of it. Like, more than you think, especially if its hot outside. A water bottle is good, but a hydration bladder is better because itll generally hold more liquid than a standard bottle. Even the strongest, most accomplished hikers are not above proper hydration. If you cant bring water with you on your hike, you shouldnt be going.

Now that weve got some of our liquids figured out, we need to get some food in our packs. The goal is to achieve a careful balance between the categories of snack and sustenance. Snacks are all about fun and flavorthink Oreos, M&Ms, those edibles youve been looking for an excuse to take. When it comes to sustenance, though, its more about making sure you have the strength to make it to the top. This is where your bananas, trail mix and pretzels come in. Only you will know the perfect balance, but you should consider the length of your hike, your general hunger level and the relative preparedness of your fellow hikers; after all, the best hiking snacks are the ones you share.

Weve got the snacks covered, but if youre like me, youre actually going to want some semblance of a meal during your hike, especially if youre walking more than a couple of miles. Enter the mid-hike sandwich. There are few rules to consider here: Youre only obligated to make the most delicious sandwich you can manage to throw together with the ingredients in your fridge. If you want to establish yourself as a hiking snack expert, though, youll add chips to your sandwich for a satisfying crunch. This meal must be eaten on a large rock overlooking a beautiful view.

Another important aspect of the hiking snack you should consider before getting on the trail is the sweet to savory ratio of your snacks. Neither snack flavor profile should take precedence over the other. If you ask me, two savory snacks and two sweet snacks usually yield the best results, but dont let that limit you; there are unlimited combinations to explore.

The summit beer: the best part of every mediocre hikers trek. Of course, if youre on a particularly difficult hike, theres a good chance youre not going to want to carry any more weight than you really need, so this one is optional. If having a can in your pack doesnt bother you, though, the summit beer can result in a revelatory moment as you rest from the hardest part of the hike. Looking out over the landscape with a beer in your hand, youll realize that your crappy bologna sandwich and lukewarm PBR are better than any restaurant meal youve ever had.

As you start your descent, legs wobbly from both the beer and too much exertion, you might just experience one of those moments of true satisfaction, a fullness not just of stomach but of soul, before you once again begin your perpetual trudge through the trees. This is why we hike. And snack.

Samantha Maxwell is a food writer and editor based in Boston. Follow her on Twitter at @samseating.

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The Anatomy of the Hiking Snack - Paste Magazine

Anatomy

Jessica Capshaw Blew Grey’s Anatomy Audition Twice, But Still Got … – Startefacts

Third time is always the charm.

If you have watched at least some parts of Grey's Anatomy, you are probably familiar with fan-favorite pediatric surgeon Arizona Robbins, portrayed by Jessica Capshaw, who was a recurring character in the medical drama from season 5 through season 14.

She was incredibly strong, positive, funny, and at times charming, and her on-screen presence was loved by so many people that some of the most loyal fans left the show after her.

It's hard to imagine the show today without Arizona Robbins. However, not many people know that she wasn't supposed to be a character at all.

Jessica Capshaw admitted that she has always loved Grey's Anatomy so much that when the chance to audition came up, she couldn't pass it up.

Two weeks after giving birth to her son, the Spanx-clad actress went to audition for Shonda Rhimes but never got the part.

That wasn't the end for the actress, however, as her performance was remembered and she was invited to audition for another role. Unfortunately, this was also a miss.

"And then, you know, they treated the people they love the way they should. They called me and said "Come in, do three episodes", and then I did, and the character grew into a series regular, which I feel very grateful and happy about," the actress recalled in her interview with Ellen DeGeneres.

Although Capshaw seemingly failed in both auditions, she managed to impress Shonda Rhimes with her writing so much that she wrote Arizona Robbins as a recurring character with a three-episode arc.

Needless to say, she turned out to be worth many more episodes, as Capshaw stayed on as a regular cast member for another 9 years.

If you're feeling nostalgic and want to relive Arizona Robbins' arc from start to finish, you can watch past seasons of Grey's Anatomy on Disney Plus, ESPN Plus and Hulu.

Or tune in every Thursday to catch up on the new season 19 episodes currently airing on ABC.

Source: TheEllenShow Youtube

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Jessica Capshaw Blew Grey's Anatomy Audition Twice, But Still Got ... - Startefacts

Anatomy

Anatomy of a game-tying goal: Desperation, chaos as Jets forced overtime – Winnipeg Sun

Things didnt work out in the end for the Winnipeg Jets on Saturday night, but that shouldnt diminish the magic moment they created by scoring a game-tying goal with 22 seconds left in the third period against the Vegas Golden Knights.

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When Adam Lowry knocked in a rebound to tie the score at 4-4, the noise in Canada Life Centre reached levels rarely heard before in Winnipeg.

It evoked memories of Dave Elletts famous double overtime goal against Edmonton in 1990 or Jacob Troubas goal that tied the Jets 3-3 with the Nashville Predators after the home side fell behind 3-0 in a 2018 playoff game.

I dont think anybody could really hear anybody on the bench

Jets defenceman Nate Schmidt

Even though the Jets lost 5-4 in double overtime on Saturday night, people in the building will remember that goal for a long, long time.

I dont think anybody could really hear anybody on the bench, Jets defenceman Nate Schmidt said. It was pretty special.

It was a pretty impressive goal for the Jets, who trailed 4-1 entering the third period but got goals from Nino Niederreiter and Mark Scheifele to make it 4-3.

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Heres how the game-tying goal unfolded:

Vlad Namestnikov dumped the puck into the Vegas zone with 1:10 to go in regulation, just as goalie Connor Hellebuyck was getting to the bench for an extra attacker.

Blake Wheeler got to the puck on the far boards but it got by him and was kept in by Neal Pionk, who threw it toward the net, creating scoring chance for Scheifele.

From there, Scheifele, Wheeler and Namestnikov had to win a puck battle on the boards before rimming it around to Kyle Connor.

Connor and Lowry both won puck battles to create a point shot for Pionk, a drive that went wide.

The puck wound up slowly rolling toward the point and William Karlsson of the Knights got to it first, needing only to get it out of the zone to likely end the game.

Karlssons one-handed attempt was cut off by Wheeler, who got the puck back down low to Connor.

From there, the puck was rimmed around all the way to Pionk at the left point. He made a great decision to throw the puck on net instead of putting it back down the boards, where the Vegas defenders were stacked up.

Pionks shot got through to Brossoit and both Lowry and Namestnikov were there, causing havoc in front of the Vegas goalie.

Lowry banged it in and pandemonium ensued.

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It was chaos, Pionk said.

A couple of big keep-ins. Guys were working hard and honestly, my mindset was just to throw pucks at the net. I knew that were under 30 seconds left and you get a rolling puck up the wall and if I throw it down the wall, it kills another five or maybe 10 seconds. If it got blocked, so be it. But I got a little lucky, threw it at the net and (Lowry) put it in.

Jets coach Rick Bowness said it was just the right amount of urgency, hard work and puck luck that combined to create the goal.

It was all about desperation, is what it was, and whatever it took to keep that puck in, Bowness said Sunday.

And give Neal Pionk a lot of credit because he saw as the puck moved from side to side it opened up and he didnt hesitate to throw it down into the net. It doesnt have to be the hardest shot, it has to get down to the net, and we had two guys down there, Vladdy and Adam, and fortunately we were able to bang home that rebound.

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Bowness said the Jets were actually not very good at scoring with their goalie pulled this season they gave up 17 empty net goals but everything came together just right on Saturday.

Those things are mostly scrambles and thats exactly what (Saturday) night was.

The puck is going over here, youve got to win then race to keep it in. It comes over here, youve got to win the race to get it back here. You get it up here, youve got to be ready to put it on the net and youve got to have somebody there.

So everything did kind of fall into place. It did help that we were desperate to keep it in that it did go east to west and up to the top and then right to the net.

Twitter.com/Ted_Wyman

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Anatomy of a game-tying goal: Desperation, chaos as Jets forced overtime - Winnipeg Sun

Anatomy

10 of Meredith Grey’s Most Iconic Moments From "Grey’s Anatomy"! – Young Hollywood

Meredith Grey is quite possibly the most famous doctor in the world Well, in the TV world anyway. She has conquered the impossible and also lived through the impossible. Sadly, her time at Grey-Sloan Memorial Hospital is coming to a close as Ellen Pompeo, the actress who plays her character, has decided to take her graceful exit from the show after 19 seasons. So, in honor of Meredith Grey, here is a roundup of all the times she was absolutely incredible on "Greys Anatomy"!

1. Meredith Finishes Her First Shift (Season 1, Episode 1)

As an aspiring surgeon, finishing her first day of work was a huge accomplishment for Meredith, allowing her to get her first real taste of what being a doctor would be like.

2. Meredith Tells Derek Shes In Love With Him (Season 2, Episode 5)

There is nothing like realizing you really love someone and you cant imagine life without them, and that is the conclusion Meredith came to in this episode. She knew that there would be a choice Derek, AKA "McDreamy", would have to make between her and his wife/ex-wife/current girlfriend (thats a story for another time), Addison Montgomery. So she mustered up the courage and told him that he should pick her because she loved him. It doesnt get any better than that, does it?

3. Holding Onto an Explosive Lodged In Someone's Body (Season 2, Episode 16)

If you watched this episode, then you know that Meredith Grey woke up that day knowing that something was going to go wrong. In fact, everyone had a bad feeling that day. And they were right. A patient rolled into the ER later that day with a live bomb inside his chest, putting everyone in the hospital at risk. But Meredith, the brave soul that she is, managed to switch places with the paramedic and stay calm enough to save the life of her patient and everybody else in the hospital.

4. Merediths First Solo Neurosurgery (Season 7, Episode 5)

A doctor's first solo surgery is a really big deal! Merediths first solo surgery was one for the books, as she worked with Derek, who was in a different OR, to help coach her through a huge surgery and, yes, it was a success!

5. Post-It (Season 5, Episode 24)

Who writes their vows on a Post-It? Derek Sheperd and Meredith Grey, that's who. And honestly, it was the cutest thing ever. Straying away from tradition and creating a new one, Derek and Meredith created a new way to write vows, and it was one for the books!

6. Meredith Has a Miscarriage While Operating on a Patient (Season 6, Episode 24)

This series of episodes was one of the most heart- and gut-wrenching episodes of "Grey's Anatomy". The hospital was sent into a frenzy as a gunman entered the hospital trying to avenge his wifes death. He was looking to kill Derek, Merediths husband. Meredith was in the early stages of her pregnancy, so the stress of the day, unfortunately, caused her to have a miscarriage. However, she was able to successfully finish her surgery on her patient and was able to reason with the gunman and convince him not to kill her husband.

7. Adopting Zola (Season 8, Episode 10)

Meredith and Derek had been trying for quite a while to adopt Zola, a baby they had treated in their hospital and instantly fell in love with. However, the adoption was proving to be a bit difficult, and they werent sure they would be able to go through with it. However, the adoption agency changed its mind and Meredith and Derek were able to have their first baby together.

8. When She Gave Birth In The Midst of a Blackout (Season 9, Episode 24)

Meredith is famous for doing some amazing things under immense pressure. This time, Meredith was able to give birth to her son in the middle of a superstorm that caused a blackout in the hospital. On top of that, she suffered some complications during her C-Section and had to direct doctors on what to do during the surgery. Luckily, in the end, everything turned out okay and she had a healthy baby boy.

9. Forgiving a Patient Who Attacked Her (Season 12, Episode 9)

Meredith is not only a hard-worker but she is also a forgiving person. She doesnt hold grudges against people because she can recognize when something isnt their fault. She showed the same compassion with a man who attacked her due to a medical issue he was suffering from. Meredith suffered a collapsed lung, broken ribs, and so much more, but she still forgave him and understood that, in her forgiveness, he would be able to move on as well.

10. Meredith Wins a Harper Avery (Season 14, Episode 7)

Winning a Harper Avery is a huge achievement in the doctor world, and Meredith Grey is among the renowned doctors who have also received one. It was well, well deserved!

As you can see, Merediths career was quite amazing, and well be sad to see her go. Ellen Pompeo is an amazing actress and she has played her role as Meredith Grey incredibly well, and her character will be missed dearly!

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10 of Meredith Grey's Most Iconic Moments From "Grey's Anatomy"! - Young Hollywood

Anatomy

Greys Anatomy Spinoff Station 19 Renewed by ABC for Season 7 – Yahoo Entertainment

ABC has renewed Station 19 for Season 7, the network announced on Thursday, along with the news that Zoanne Clack and Peter Paige will serve as showrunners and executive producers for the upcoming installment. They take over for Krista Vernoff, whose departure was announced in January.

I feel incredibly honored to be entrusted with this dynamic and relevant show alongside Peter. The diversity of the cast, writers, and crew in addition to their enormous talent and dedication to their craft makes this a thrilling adventure to undertake, Clack said. We are excited about the stories we get to tell using this worldwide platform and both understand the responsibility of being able to share them as we reach into millions of homes weekly.

Im beyond honored to be handed the reins to Station 19 a show I love, full of incredible, complex characters, and resonant, important stories, Paige said. To get to partner with a talent like Zoanne as showrunners truly makes it all the more exciting we share a similar vision for the show, and weve got some incredible twists and turns planned for the coming season. A huge thank you to the entire team at Shondaland, and everyone at ABC for their faith in us.

Also Read:The Good Doctor Renewed for Season 7 at ABC

Clack became head writer and executive producer on Station 19 in 2022 and stayed on as an executive producer on Greys Anatomy, where she has been since it began, assisting in the formulation and production of all medical aspects of the show. She is represented by CAA.

Paige began his career in Hollywood as an actor and played one of the leads in Showtimes Queer as Folk. Since transitioning to writing/directing, he co-created The Fosters and Good Trouble. He joined Station 19 as a director in 2020 during Season 4 and became an executive producer starting with Season 6. Paige is represented by Anonymous Content and Jackoway, Tyerman, Wertheimer, Austen, Mandelbaum, Morris, & Klein.

The series is produced by ABC Signature, a part of Disney Television Studios, and Shonda RhimesShondaland.

Also Read:Greys Anatomy Renewed for 20th Season on ABC

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Greys Anatomy Spinoff Station 19 Renewed by ABC for Season 7 - Yahoo Entertainment

Anatomy

Vishal’s Mark anatomy is to be out on this date – Filmy Focus

Vishal is working on a different crime drama titled, Mark Antony. Touted as a crime comedy thriller, already Vishals getup for the film is out which has been receiving positive response from the audience.

Meanwhile, the latest news is that the films first look teaser is going to be unveiled on April 27th at 6:30 PM. An official announcement regarding the same came out this evening.

Directed by Adhik Ravichandran, the film has Ritu Varma as the female lead. Co-starring SJ Suryah, Sunil, and Abhinaya in key roles, Mark Antony is gearing up for theatrical release sometime in late summer.

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Vishal's Mark anatomy is to be out on this date - Filmy Focus

Anatomy

May season finale dates on ABC: The Good Doctor, Greys Anatomy and more – WOODTV.com

Grey's Anatomy. Photo courtesy of ABC/Raymond Liu. NIKO TERHO, JANAI KAYLANI

GRAND RAPIDS, Mich. (ABC 4)- May will be an exciting month for fans of ABCs primetime series! Not only will the broadcast network air new seasons of hit shows like The Bachelorette, Celebrity Family Feud and Press Your Luck, but theyll also debut new series like The Prank Panel and Jeopardy! Masters to viewers.

May also brings an array of season finales. Dont miss the upcoming finales of The Good Doctor, The Conners and more. Refer to the TV schedule below and set your reminders to tune in on ABC 4 West Michigan.

The Good Doctor

Time: 10 p.m.

Episode title: Loves Labor

The Rookie

Time: 8 p.m.

Episode title: Under Siege

The Rookie: Feds

Time: 9 p.m.

Episode title: Red One

Will Trent

Time: 10 p.m.

Episode title: A Bad Temper and a Hard Heart

The Conners

Time: 8 p.m.

Episode title: The Grad Finale

The Goldbergs

Time: 8:30 p.m.

Episode title: Bev to the Future

Not Dead Yet

Time: 9:30 p.m.

Episode title: Not Just Yet

A Million Little Things

Time: 10 p.m.

Episode title: One Big Thing

The Company You Keep

Time: 10 p.m.

Episode title: The Truth Hurts

Celebrity Wheel of Fortune

Time: 9 p.m.

Episode title: Vanna White, Ken Jennings and Mayim Bialik

Station 19

Time: 8 p.m.

Episode title: TBA

Greys Anatomy

Time: 9 p.m.

Episode title: TBA

Shark Tank

Time: 8 p.m.

Episode title: TBA

Jeopardy! Masters

Time: 8 p.m.

Episode title: TBA

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May season finale dates on ABC: The Good Doctor, Greys Anatomy and more - WOODTV.com

Anatomy

‘Grey’s Anatomy’ and ‘Scandal’ creator Shonda Rhimes says being showrunner on ‘Bridgerton’ spinoff ‘Queen Char – Business Insider India

"Grey's Anatomy" and "Scandal" creator Shonda Rhimes said that she is happy to be back in the role of creator and showrunner of the new "Bridgerton" spinoff, "Queen Charlotte."

While Rhimes is an executive producer on "Bridgerton," the show was created by Chris Van Dusen, who served as showrunner for its first two seasons.

Rhimes, however, helped create the new prequel series based on Queen Charlotte (played by Golda Rosheuvel) and her rise to the throne.

While attending a special fan screening of "Queen Charlotte" in London, England, last Friday, Rhimes spoke to Insider about stepping into the role of showrunner for the first time in the "Bridgerton" franchise.

"It was simple," Rhimes said. "I've been doing showrunning for so long and for so many years that it was really fun to get to be a producer on 'Bridgerton' and look at it from a whole." "But it's like coming home to sit down and write again.'

Prior to "Queen Charlotte," Rhimes created the limited series "Inventing Anna" for Netflix, and before that, her last creator credit was "Scandal" starring Kerry Washington.

In recent years, Rhimes has instead worked with other writers and producers to launch shows like "How to Get Away with Murder" and "Station 19" through her Shondaland production company.

While on the red carpet at the special screening, Rhimes also told reporters that if she had to pick another "Bridgerton" character to get their own prequel series, it would be Violet Bridgerton (played by Ruth Gemmell).

In the "Queen Charlotte" series, fans will see a younger version of Violet played by Connie Jenkins-Greig.

Jenkins-Greig told Insider on the red carpet that we will see an "inquisitive" version of Violet who "questions everything" in the new show.

"She still always keeps a sense of herself. She has a beautiful relationship with her dad," the young actor said, adding that she is keen to reprise her role if there is another prequel.

The series will also feature younger versions of Lady Danbury (originally played by Adjoa Andoh), King George (originally played by James Fleet), and Queen Charlotte's chief secretary Brimsley (originally played by Hugh Sachs).

"Queen Charlotte: A Bridgerton Story" premieres on Netflix on May 4.

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'Grey's Anatomy' and 'Scandal' creator Shonda Rhimes says being showrunner on 'Bridgerton' spinoff 'Queen Char - Business Insider India