All posts by medical

ABC renews Grey’s Anatomy, Scandal, and How to Get Away With Murder – EW.com

February 10, 2017 medical

Great news, TGIT fans: ABC has given early renewals to Greys Anatomy, Scandal, and How to Get Away With Murder.

The pickup news means Greys Anatomy will hit season 14, Scandal will make it to season 7, and How to Get Away With Murder will continue into season 4.

Greys Anatomy, Scandal, and How to Get Away With Murder continue to keep viewers on the edge of their seats and wanting more, says ABC Entertainment President Channing Dungey of the Shonda Rhimes-produced trio. Im thrilled to bring back these shows and the OMG moments that come with them.

This season, Scandal was delayed until midseason to accommodate Kerry Washingtons pregnancy, meaning TGIT was not part of the fall lineup new series Notorious aired in Scandals timeslot and didnt gain much traction. Dungy previously admitted to EW about being nervous over postponing Scandals return. Scandal is a big hit show for us and nobody likes to go into their first fall season as president of entertainment without one of the biggest guns in their arsenal, she said. But, obviously we were thrilled for Kerry and her family and thats all good news.

No decisions have been made in terms of Scandals episode count or whether it will be on in the fall or launch again in midseason Dungey previously said it was too early to tell whether shed repeat history and have another TGIT-less fall. I havent even had the opportunity yet to read the pilot scripts that are in development, so for me to posit what next falls going to look like is a little too early, she said.

RELATED: Hear more of the latest TV news from this week

Scandals absence also affected How to Get Away With Murder, which has been strong creatively, but not in the ratings. I think the lead-in certainly bears some responsibility, Dungey has said. Notorious did not perform as strongly as we would have hoped But if you look at How to Get Away With Murder over the seven-day period, we generally go up in triple-digit percentages, an average of 115 to 117 percent for the show. So that signals that people are still as engaged with it as before. I do think that the lack of TGIT pull-through did affect the number a little bit.

As for Greys Anatomy, Dungey seemed optimistic about the show continuing for many seasons to come, and possibly rivaling ERs tenure. Thatd be lovely, Dungey told EW. Ill take even more! Honestly, I think that the show is going to continue as long as Shonda and the gang have a creative passion for telling those stories. At the moment, it feels like were full steam ahead.

Greys Anatomy, Scandal,and How to Get Away with Murder air Thursdays at 8 p.m. ET, 9 p.m. ET and 10 p.m. ET, respectively, on ABC.

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ABC renews Grey's Anatomy, Scandal, and How to Get Away With Murder - EW.com

Anatomy

The anatomy of a banked-in 3-pointer – Lynchburg News and Advance

February 10, 2017 medical

A.C. Reid is making a habit of banking in 3-point shots with the outcome of Libertys most recent games hanging in the balance.

He banked in a 3 from the left wing as time expired to lift the Flames to a dramatic victory over Radford one week ago at the Vines Center. The junior guard needed the backboard again, this time Thursday night against Gardner-Webb at Paul Porter Arena, to force a second overtime and cap the Flames remarkable comeback win against the Runnin Bulldogs.

What has led to Reid having the confidence to make those shots? The 6-foot-5 guard has never lacked the confidence to take shots since he arrived on campus, but he has become better at shooting off the dribble and with bigger players contesting his shot.

Those two aspects have greatly assisted Reid in getting the shots up quickly and accurately, even though hed prefer his shots to swish through the net instead of banking in off the backboard.

I think its actually kind of difficult to go from that far and try to bank a shot in, Reid said. Ive been blessed these past two games to hit both of those shots.

Reids transformation has steadily taken place this season. His first two seasons were highlighted by his ability to make multiple 3-pointers in a row, but also to be easily pushed off the 3-point line and not get a shot off if he didnt get a clean look to catch and shoot.

Former Liberty basketball player Alex McLean joined the coaching staff as a graduate assistant this season and the players have credited his work with them on improving all facets on the offensive end.

He has particularly worked with Reid and fellow junior guard Ryan Kemrite during drills about two hours before each game on dribbling and shooting, catching and shooting and finishing their shots through contact.

Once that is completed, McLean and Reid begin shooting from midcourt in a challenge to see who can make the most attempts.

Alex does a great job with us and even the coaching staff does a great job with us of just getting a lot of game shots, Reid said. Coach [Ritchie] McKay said it in film the other day, If A.C.s going to be taking those deep shots, then yall need to be practicing that with him in his individual work. I think its just getting those constant reps that will give me the confidence just to take those deep shots during the game.

Reid missed his first five 3-point attempts against Radford before connecting on the banked-in attempt. He caught the inbounds pass from Georgie Pacheco-Ortiz, dribbled to his left and shot from about 24 feet over the outstretched arms of Radford 6-foot-8 center Randy Phillips.

Reid made his first two 3-pointers against Gardner-Webb, but missed five straight long-range attempts before he connected from 30 feet with 1.5 seconds remaining in the first overtime.

Reids shot came in a disjointed sequence as the Flames quickly attempted to get an open look. Pacheco-Ortiz handed the ball off to Reid, who took one dribble in and unleashed his shot from the right wing as GWU 6-foot-6 forward DJ Laster reached out his arm to contest.

I think when youre a confident shooter, youre a confident shooter and he is that, McKay said. He walks on the floor thinking hes going to make the shot. The fact that hes hit a couple of banks probably is attributed more to his nature and his fearlessness than his confidence. He thinks hes going to have a chance to make it.

McKay said Reid has earned the trust from the coaching staff through his leadership and overall IQ. That is a stark contrast to last season when McKay said he was really frustrated with him and Im not sure he liked me so much. I wasnt having any fun coaching him.

But that has changed with Reid being one of the first players off the bench and one of the five who is on the floor in the final minutes. McKay said Reid makes the offense better when hes on the court, and that comes from Reid having the green light to shoot it from any point as the shot clock is winding down.

I dont think I ever lack confidence in my shot. I feel like every shot I take is going in, Reid said. I think that just comes from the reps that Ive taken and the reps Ive completed over the last few years. Im going to continue to take shots because my coaching staff has empowered me to do so.

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The anatomy of a banked-in 3-pointer - Lynchburg News and Advance

Anatomy

Beyonc’s Lemonade Director Enlists Grey’s Anatomy’s Jesse Williams for His Latest Fashion Spectacle – Vanity Fair

February 10, 2017 medical

Left, Khalil Joseph, March 2015; Right, Humberto Leon and Jesse Williams at the Music is My Mistress premiere party on February 9, 2017.

Left, by Owen Kolasinksi/BFA/Rex/Shutterstock; Right, courtesy of Donato Sardella/Getty Images/Kenzo.

Kahlil Joseph, the writer-director who co-helmed Beyoncs epic visual-concept album, Lemonade, has debuted his latest work of arta film for the French luxury brand Kenzo.

The auteur has partnered with Kenzos creative directors, Carol Lim and Humberto Leon, to make an original short film, Music Is My Mistress, that features the labels chicest looks from their spring/summer 2017 collection. Greys Anatomy star Jesse Williams stars as a lost music manager searching for an African luminary played by newly minted Golden Globe winner Tracee Ellis Ross (from TVs Black-ish).

The film is about blackness, Joseph told Vanity Fair at a special screening party held at L.A.s Underground Museum on Thursday night. He went on to explain that his objective was to portray African-Americans realistically on-screen in the way they move, talk, and interact with people.

The theme of blackness is also prevalent in Lemonade. Since working with Beyonc on her visual spectacle, the Grammy-nominated director says his life is relatively the same. Hes just thankful that the opportunity to work with his close pal finally came to fruition.

I have known Beyonc through friends for a while, and we had talked about working together on stuff in the past, said Joseph, who has also worked with Kendrick Lamar and film director Terrence Malick. Lemonade was the one that just made sense to work together. It was an important and personal story.

For Williams, who is an outspoken human-rights activist, creating a piece of art like Kenzos short film is more important than ever now that uncertaintyand fearis gripping the nation in the Trump era.

The art community means a tremendous amount in times of bliss and in times of peril. The world is in a very contentious moment right now, and its all the more important now for people to be able to create daring, inclusive, forward-leaning material that is challenging for the status quo, Williams told Vanity Fair. Artists shake shit up and they drive the conversation and establish a new stake in the ground. Its so important to keep on doing this.

But some critics believe celebrities and artists should keep their political opinions to themselves, saying they live in a privileged world and have no real understanding of the issues faced by others. Williams strongly objects to that idea.

Actors should talk and to continue to speak up about politics. Acting is a job. A career. If Im a plumber, can I only fix pipes? If Im a teacher, can I only teach? If thats a rule, its fucking bizarre and ridiculous, he explained. I cant care about being a member of the electorate and what happens in the legislative office? Its asinine. I have been a politically active, social-justice activist my whole life, and I happened to have started acting. I think people should do what they want to do.

Williams, who made headlines in June for a speech he gave at the B.E.T. Awards, vows to fight relentlessly against social injustice and to continue to provide entertainment through his acting career.

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By Carl Timpone/BFA.com.

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Beyonc's Lemonade Director Enlists Grey's Anatomy's Jesse Williams for His Latest Fashion Spectacle - Vanity Fair

Anatomy

Grey’s plays out the Trump worldview against a hospital backdrop – A.V. Club

February 10, 2017 medical

Feb 10, 2017 6:00 AM

Because The A.V. Club knows that TV shows keep going even if were not writing at length about them, were experimenting with discussion posts. For certain shows, one of our TV writers will publish some brief thoughts about the latest episode, and open the comments for readers to share theirs.

Previous episode Meredith searches for Alex while Greys Anatomy searches for a purpose

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Grey's plays out the Trump worldview against a hospital backdrop - A.V. Club

Genetics

The Tragic Story Of Soviet Genetics Shows The Folly Of Political Meddling In Science – IFLScience (blog)

February 9, 2017 medical

A few years ago, one of us (Ian) was lucky enough to be invited to visit the N.I. Vavilov Institute of Plant Industry in St Petersburg, Russia. Every plant breeder or geneticist knows of Nikolai Vavilov and his ceaseless energy in collecting important food crop varieties from all over the globe, and his application of genetics to plant improvement.

Nikolai Vavilov was pilloried because he wasnt a political favourite in Soviet Russia. Library of Congress. New York World-Telegram & Sun Collection

Vavilov championed the idea that there were Centres of Origin (or Diversity) for all plant species, and that the greatest variation was to be found in the place where the species evolved: wheat from the Middle East; coffee from Ethiopia; maize from Central America, and so on.

Hence the Centres of Origin (commonly known as the Vavilov Centres) are where you should start looking to find genotypes the set of genes responsible for a particular trait with disease resistance, stress tolerance or any other trait you are looking for. This notion applies to any species, which is why you can find more human genetic variation in some African countries than in the rest of the world combined.

By the late 1920s, as director of the Lenin All-Union Academy of Agricultural Sciences, Vavilov soon amassed the largest seed collection on the planet. He worked hard, he enjoyed himself, and drove other eager young scientists to work just as hard to make more food for the people of the Soviet Union.

However, things did not go well for Vavilov politically. How did this visionary geneticist, who aimed to find the means for food security, end up starving to death in a Soviet gulag in 1943?

Heroic science?

Enter the villain, Trofim Lysenko, ironically a protg of Vavilovs. The notorious Vavilov-Lysenko antagonism became one of the saddest textbook examples of a futile effort to resolve scientific debate using a political approach.

Lysenkos theories went against the latest science, but prevailed due to politics. Wikimedia

Lysenkos name leapt from the pages of history and into the news when Australias Chief Scientist, Alan Finkel, mentioned him during a speech at a meeting of chief scientists in Canberra this week.

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The Tragic Story Of Soviet Genetics Shows The Folly Of Political Meddling In Science - IFLScience (blog)

Genetics

Myriad Genetics: Fairly Valued? – Barron’s (blog)

February 9, 2017 medical

By Ben Levisohn

When a stock has been beaten up as badly as Myriad Genetics (MYGN) hasits dropped 57% during the past 12 monthsit doesnt take much to move it higher. So it shouldnt come as too much of a surprise that shares of Myriad are soaring today after the genetic testing company beat earnings forecasts and offered upbeat guidance.

Myriad reported a profit of 26 cents a share, topping forecasts for 24 cents, on revenue of $196.5 million, beating the Street consensus for $190.1 million. Myriad also said it expects to earn between $1 and $1.05 in 2017, ahead of analyst forecasts of 98 cents.

So is the worst over? Maybe, but Cowens Doug Schenkel and team argue that Myriads shares are fairly valued. They explain why:

Myriad remains in a transformation phase and visibility on the revenue growth outlook continues to be limited. For example, there are several key decisions in the next 3 months that could affect Myriads outlook, including: (1) a CMS Editorial review board to review CPT coding for hereditary cancer panels (Feb. 10-11; link); (2) a final Vectra DA CMS reimbursement decision (LCD comment period ends March 23); (3) a final Prolaris LCD intermediate risk decision (comment period ends March 23); and (4) a UHC contract decision for hereditary cancer testing (current contract ends in May).

Although the share price continues to decline, we still believe shares are about fairly valued considering the number of uncertainties across business segments. Relative to peers Myriad still trades at a slight P/E premium, but at a ~30% EBITDA discount.

Shares of Myriad Genetics have jumped 10% to $16.99 at 10:38 a.m. today.

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Myriad Genetics: Fairly Valued? - Barron's (blog)

Cell Biology

IFT20 protein’s role in helping cancer cells to invade – Medical Xpress

February 9, 2017 medical

February 9, 2017 The functions of Ror2 and IFT20 in invasive cancer cells. In healthy cells IFT20 regulates the formation and function of primary cilia. Many cancer cells lack cilia, and these cells induce and sustain the expression of IFT20 through the high expression of Ror2. IFT20 promotes the formation of Golgi-derived microtubules by binding with the GM130-AKAP450 complex in Golgi. By doing this it regulates the deployment of Golgi and transport of proteins within Golgi, both important parts of the formation of invadopodia. Credit: Kobe University

An international research team has discovered that the IFT20 protein helps some cancer cells to invade by facilitating the transportation of membranes and proteins within parts of the cell.

Primary cilia exist on the surface of almost all human cells, acting as "cell antenna" that receive information from outside the cell. IFT20 (intraflagellar transport 20) is a protein present in most human cells that plays an essential role in the formation and functions of these primary cilia. In healthy cells it acts as a "cargo adaptor" to transport proteins along microtubules within cilia, but many cells lose these cilia when they become cancerous. This research has shed light on the function of IFT20 in non-ciliated cancer cells for the first time. The discovery has potential applications for developing new cancer treatment methods that block invasive cancer cells by targeting IFT20. The findings were published on January 26 in the online edition of Scientific Reports.

This research was carried out by an international team including Associate Professor NISHITA Michiru (Kobe University Graduate School of Medicine Department of Physiology and Cell Biology), Professor MINAMI Yasuhiro (Kobe University Graduate School of Medicine, Department of Physiology and Cell Biology), Professor Victor W. Hsu (Harvard Medical School) and Professor Gregory J. Pazour (University of Massachusetts Medical School). Most cancer-related deaths are said to be caused by cell invasion and the consequent spread of cancer cells to other parts of the body (metastasis). To counter this, scientists are searching for the mechanism that controls the invasive properties of cancer cells.

Researchers already knew that a cell membrane protein known as Ror2 expresses highly in various cancer cells, and it promotes cancer cell invasion and metastasis. Professor Nishita's team investigated various kinds of non-ciliated cancer cells and discovered that Ror2 promoted cancer cell invasiveness by inducing the expression of IFT20.

Many tumor cells break through the barrier of the extracellular matrix and infiltrate their surroundings by forming protruding structures known as invadopodia (see figure). The formation of invadopodia requires membranes and proteins supplied by the intracellular transport system, using the Golgi complex. The Golgi complex must be close to invadopodia to deploy these materials. The team's findings demonstrate that in tumor cells, IFT20 induces the Golgi complex to form microtubules by promoting interaction between the Golgi proteins GM130 and AKAP450. It also regulates the structure of the Golgi complex and transport of proteins within the complex. "This research has clarified a new molecular mechanism related to the formation of Golgi-derived microtubules, and its important role in invasive cancer cells," said Professor Nishita.

The relationship between loss of cilia and a cell's cancerous properties remains unclear. IFT20 is involved in the formation and function of cilia in healthy cells, but in non-ciliated cancer cells it is now clear that IFT20 is responsible for the formation of invadopodia. By continuing to analyze the relationship between IFT20 and the loss of cilia, this line of research could help shed light on the fundamental question of why many cancer cells lack cilia. Additionally, if the specific regulatory mechanism of IFT20 in cancer cells is revealed, this knowledge could be used to develop treatment that targets IFT20 to block invasive cancer cells.

Explore further: Study reveals gene's role in male infertility

More information: Michiru Nishita et al, Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness, Scientific Reports (2017). DOI: 10.1038/s41598-016-0028-x

Journal reference: Scientific Reports

Provided by: Kobe University

A Virginia Commonwealth University-led research team has opened a fresh direction in the field of male infertility with a new study that examines the role of a particular gene in the formation of sperm flagella, which is ...

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Scientists at the Universities of York and Texas have found that a component of cancer cells, which acts like a 'cellular post office', could be the key to preventing the spread of lung cancer to other parts of the body.

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Genetics

Fulgent Genetics to Announce Fourth Quarter and Full Year 2016 Financial Results on February 27, 2017 – GlobeNewswire (press release)

February 8, 2017 medical

February 08, 2017 08:00 ET | Source: Fulgent Genetics, Inc.

TEMPLE CITY, Calif., Feb. 08, 2017 (GLOBE NEWSWIRE) -- Fulgent Genetics, Inc. (Nasdaq:FLGT) (Fulgent Genetics or thecompany) today announced that its fourth quarter and full year 2016 financial results will be released after market close on Monday, February 27, 2017 . The companys Chairman and Chief Executive Officer Ming Hsieh, its Chief Science officer Dr. Harry Gao, and its Chief Financial Officer Paul Kim will host an investment community conference call the same day at 5:00 PM ET (2:00 PM PT) to discuss the results and answer questions.

The call can be accessed through a live audio webcast in the Investor section of the companys website, http://www.fulgentgenetics.com, and through a live conference call by calling 1-855-321-9535, passcode # 65226206. An audio replay will be available in the investors section of the companys website or by calling 1-855-859-2056 through March 6, 2017.

About Fulgent Genetics

Fulgent Genetics is a rapidly growing technology company with an initial focus on offering comprehensive genetic testing to provide physicians with clinically actionable diagnostic information they can use to improve the overall quality of patient care. The company has developed a proprietary technology platform that integrates sophisticated data comparison and suppression algorithms, adaptive learning software, advanced genetic diagnostics tools and integrated laboratory processes. This platform allows the company to offer a broad and flexible test menu while maintaining accessible pricing, high accuracy and competitive turnaround times. The company believes its current test menu, which includes more than 18,000 single-gene tests and more than 275 pre-established, multi-gene, disease-specific panels, offers more genes for testing than its competitors in todays market, which enables it to provide expansive options for test customization and clinically actionable results.

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Fulgent Genetics to Announce Fourth Quarter and Full Year 2016 Financial Results on February 27, 2017 - GlobeNewswire (press release)

Embryology

Center of Excellence for Poultry Science Hosts Open House for High School, Transfer Students – University of Arkansas Newswire

February 8, 2017 medical

Photo by Sara Landis

Keith Bramwell, extension reproductive physiologist, assists a student during an embryology workshop at the Open House hosted by the Center of Excellence for Poultry Science.

FAYETTEVILLE, Ark. The Center of Excellence for Poultry Science at the U of Arecently sponsored an Open House for high school juniors, seniorsand college transfer students. Fifty participating students came from Missouri, Texas, Oklahoma, Kansas, Illinois and Arkansas, and included prospective 3-plus-1 program transfer students from the University of Arkansas at Pine Bluff and Arkansas State University.

The 3-plus-1 Certificate of Poultry Science program allows for agriculture majors with an animal science option at UAPB to take poultry science classes at the University of Arkansas as seniors. Those courses are recognized by UAPB's School of Agriculture, Fisheries and Human Sciences, and count toward degree requirements. At the same time, those students earn a Certificate of Poultry Science from the University of Arkansas. Completion of the certificate requires 26-28 hours of poultry science credit.

The Open House provided an opportunity for prospective students to meet poultry science faculty, tour poultry science facilities and learn about the many career opportunities available with a major in poultry science. There were three workshops students participated in: Cell and Molecular Biology, Embryologyand Food Product Technology.

"The Center of Excellence for Poultry Science Open House was a real eye opening experience for our UAPB students," said UAPB interim assistant dean for academic programs and extension livestock specialist David Fernandez. "Having the abilityto physically see the opportunities they would have as part of the UAF/UAPB 3-plus-1 Poultry Science Program generated a lot of excitement and discussion about their future plans."

Students participated in the Open House and afterwardattended the Arkansas-LSU basketball game.

Editor-selected comments will be published below. No abusive material, personal attacks, profanity, spam or material of a similar nature will be considered for publication.

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Center of Excellence for Poultry Science Hosts Open House for High School, Transfer Students - University of Arkansas Newswire

Embryology

Wilmington volunteer recognized with 4-H state award – Port City Daily

February 8, 2017 medical

PortCityDaily.com is your source for free news and information in the Wilmington area.

WILMINGTON 4-H volunteers from across North Carolina gathered Feb. 4 to celebrate their accomplishments through the North Carolina 4-H State Awards Recognition program. The awards ceremony was held at the Sheraton Imperial Hotel and Convention Center in Durham, N.C., and was attended by 4-H awards delegates, their families, 4-H staff members and volunteers, industry partners and sponsors.

Related reading:Communities In Schools: Changing lives one student at a time in Brunswick County

Melissa Hight of Wilmington, was recognized for outstanding service and commitment to the 4-H school enrichment program, Embryology in the Classroom. Melissa has made tremendous improvements to the program that brings fertilized chicken eggs to 2nd graders across New Hanover County. She also obtained funding from New Hanover County Farm Bureau to sponsor this program.

Melissa has brought embryology to several new schools, extending our reach to over 100 additional students this year. She also shares a lesson from the 4-H Embryology curriculum with students, going above and beyond by bringing props and energy with her. She leaves each classroom with a book about chickens and Im an EGG-cellent Kid! stickers.

These changes have taken a good program and made it great. Not only are students learning important facts about the life cycle of a chicken, they are also learning what 4-H is about and that it can be fun.

Leslie Dill serves as New Hanover Countys 4-H Agent. She received a B.A. in animal science from The Ohio State University and an M.A. in agriculture and extension education from N.C. State University. She can be reached at 910-798-7660 or leslie_dill@ncsu.edu.

4-H, the largest youth development organization in the world, is a community of seven million young people across the globe learning leadership, citizenship, and life skills. To learn more about New Hanover County 4-H, visit newhanover.ces.ncsu.edu.

-Content provided by Leslie Dill, 4-H Youth Development

This content was provided by a community member via Local Shout, a new initiative at Port City Daily. Port City Daily cannot guarantee the accuracy of information presented in this story. If you have additional information or would like to submit a story, please contact shout@portcitydaily.com.

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