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PNN leads elementary awareness event about neuroscience – The Daily Princetonian

On Friday, March 31, elementary school students without any previousexposure to the field of neuroscience were guided in constructinga network of neurons using pipe cleaners. The exercise was part of an effort by University students to expose students at the Christina Seix Academy to a field often excluded to more privileged environments.

The Princeton Neuroscience Network, a student-led group that fosters greater awareness and appreciation for neuroscience, held its first major outreach event on March 31. The fourth-grade students from Christina Seix Academy, a school founded to provide education to children from low-income, single-parent households, were brought to the Princeton NeuroscienceInstitute to engage in a series of activitiesabout science and the brain during the University's first Neuroscience Fair.

"I liked it a lot. It taught us a lot of things we didn't know before. We went in not knowing a lot about the brain, but we came out knowing much more," said Serenity Davis, a student at Christina Seix.

Heads of the PNN Outreach Committee Chi-Chi Azoba '18 and Selam Zenebe-Gete '18 explained that it was important to them as STEM students to spread awareness of neuroscience and to share the University's many resources.

As women of color, getting students to come here and see us perform as student leaders has been empowering Azoba explained.

Azoba and Zenebe-Gete, both juniors concentrating in Molecular Biology at the University, have been planning this event since their freshman year, when they started the Outreach Committee of Princeton Neuroscience Network after meeting one of PNNs co-founders, Seong Jang 18.

We had this vision freshman year to expose younger students to neuroscience since neuroscience had never been introduced to us as children, Azoba noted.

Since its creation two years ago, PNN has been engaging with University students through study breaks, movie screenings with professors, and research symposiums. According to Jang, however, the group felt that it was time for PNN to engagewith a wider community.

We want PNN to grow from all branches, explained Jang, referring to PNNs events, research, and outreach efforts.

Jang hopes that through outreach efforts such as this fair, those interested in neuroscience at the University can enhance their experiences while positively impacting the surrounding community.

Consisting of a series of blocks or activities the children rotated through, the Neuroscience Fair engaged students in a variety of ways as they learned about the different parts of the brain, their functions, and how these parts of the brain affect perception and understanding. For example, one block allowed the children to watch Princeton students dissect a sheep brain, during whichPNN volunteers showed them the functions of each part of the brain. Another block allowed the children to monitor the electrical activity of muscles using a Muscle SpikerBox.

Students of Christina Seix Academy left the University not only with a stronger understanding of the brain and of the field of neuroscience, but with an appreciation for science and a desire to pursue neuroscience in the future. In addition, exposure to the University community delighted Academy students, who expressed their fascination withthe campus.

"Have you seen the movie "Groundhog Day"? I wish today was my groundhog day so I could come here every day!" said Academy student Justin Hogue.

Some children, according to teachers at the academy, have even set goals since their visitof becoming students at the University someday.

"The Neuroscience Fair sparked something in our students. It made them curious and excited to learn more about their brain and learning, " said Nicole Morillo, a teacher at Christina Seix.

"The students absolutely loved every minute of the Neuroscience Fair. It broadened their understanding and increased their enthusiasm about science," said Ashley Umberger, another teacher at the Academy.

Seeing their project come to fruition with such success, PNN leaders said they encourage and are optimistic about their organizationalgoals. One of these goals is to hold a conference here at the University that willbring together professors, students, and researchers from other institutions who are interested in neuroscience.

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PNN leads elementary awareness event about neuroscience - The Daily Princetonian

Belarus, Russia plan to set up joint breeding and genetics centers – Belarus News (BelTA)

MINSK, 4 April (BelTA) Belarus and Russia have plans to establish joint breeding and genetics centers, Belarusian Agriculture and Food Minister Leonid Zayats told reporters on 4 April, BelTA has learned.

The minister said that the meeting held in Saint Petersburg on 3 April discussed matters related to the establishment of joint breeding and genetics centers with a view to reducing the import of pedigree stock. The countries of Europe are facing serious animal health problems, including avian flu, African swine fever, bluetongue disease and other diseases. This is unsafe for our country, so we should preserve what we have achieved in livestock farming, he emphasized.

The breeding and genetics centers will likely be set up at the research agencies of the two countries. Plans have been made to establish centers for dairy cattle breeding, pig breeding, and broiler farming. We should preserve our potential in genetics and animal breeding, Leonid Zayats said.

The minister noted that the matter will be discussed at the session of the Supreme State Council of the Union State to be held in Russia in the near future.

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Belarus, Russia plan to set up joint breeding and genetics centers - Belarus News (BelTA)

Australian scientists begin world’s largest genetic study into depression – ABC Online

If youve ever been treated for depression, your saliva sample and survey responses could help inform the worlds biggest genetic investigation into the illness.

The Australian Genetics of Depression Study has been launched as part of an international collaboration aiming to identify genes that predispose people to depression.

The results of the research will eventually help eliminate the guesswork involved in treatment, according to the countrys lead investigator Professor Nick Martin from the Q-I-M-R Berghofer Medical Research Institute.

At the moment if somebody goes to their doctor with depression they get put on one of the standard drugs and it works for some people, but doesnt work for a lot of them, he told Hack.

Professor Martin said many need to experiment with different medications and struggle to find the right fit.

What we need to do is try and take the hit-and-miss out of treatment and try to make a predictive test which will be based upon genetics."

Previous research has identified particular genetic regions of DNA associated with depression and shown the illness can run in families.

While environmental factors also play a part, the aim of this research is to create more targeted treatment by using genetics to predict which medications will work for which people.

To get the data they need, researchers require about 20,000 adult participants across Australia.

19-year-old Kayla Gonzalez is a forensic science student and musician from Victoria.

She has been treated for depression since she was 16 and was an early participant of the study.

Kayla told Hack research like this is crucial.

My family - two to three generations back - has a history of either depression or bipolar.So for me, if I could do this study and I could have kids and be able to stop them from having to go through [depression] that is fantastic.

She added she was lucky she didnt have to mess around with meds too much, but saw her how laborious it was for her mother.

Just having to go through that constant guess work can trigger so many more issues. I think if we can eradicate that mismatched part of it and figure out what works well for [individuals] it would have such a good impact, she said.

She said it would also help prevent teen suicide.

Researchers have called for more people like Kayla to take part.

Were at a stage now of medicine where the biggest aid we can get is not even people giving us government money - although thats necessary its actually volunteers from the community who are willing to go a little bit out of their way to help medical research, Professor Martin said.

The number of antidepressant subscriptions in Australia has increased massively over the past 10 years.

Professor Martin said the research will also look side effects of antidepressants, including how they impact libido.

The idea would be to design to new drugs that are efficacious and that dont come with these undesirable side effects, he said.

I would hope within 10 years were seeing the fruits of this in new medications.

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Australian scientists begin world's largest genetic study into depression - ABC Online

Why NewLink Genetics Shares Fell 10.3% Today – Motley Fool

What happened

After reporting that a mid-stage clinical trial stumbled,NewLink Genetics Corporation (NASDAQ:NLNK)shares lost 10.3% of their value today.

Last year, attention shifted to NewLink's IDO-inhibiting cancer drug pipeline after its once-promising algenpantucel-L failed to achieve its primary endpoint in phase 3 trials.

IMAGE SOURCE: GETTY IMAGES.

This morning, investors got a closer look at interim data from a phase 2 trial evaluating its IDO-inhibitor indoximod, and despite arguably competitive response rates, investors were disappointed.

In its trial, indoximod was used alongside Merck & Co. checkpoint inhibitor Keytruda in 60 patients diagnosed with advanced melanoma. The objective response rate to the combination was 52%, and the disease control rate was 73%. For reference, the disease control rate includes patients determined to have a complete response, a partial response, or stable disease.

These were solid rates, but investors appear worried that they might not match up as competitively to Incyte's competing IDO-inhibitor,epacadostat. In smaller phase 1 trials involving 19 patients, the ORR for epacadostat plus Keytruda was 58%.

Indoximod development is continuing as planned, and earlier this year, management reported that its spending on indoximod's R&D will increase substantially as trials expand to include more patients and cancer indications.

Investors should also see initial results for another IDO-inhibitor later this year. The company's GDC-0919 attempts to inhibit IDO in a way that's more similar to Incyte's drug than indoximod, and collaboration partnerRoche Holdings is expected to report some phase 1b data in the second half of 2017.

Overall, there's a lot going on at this company, and while the data might not have been as robust as hoped to justify the uptick in development expenses, it seems to me like today's drop was more "sell the news" than anything else.

Todd Campbell has no position in any stocks mentioned.His clients may have positions in the companies mentioned.The Motley Fool has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy.

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Why NewLink Genetics Shares Fell 10.3% Today - Motley Fool

Cancer Genetics, Mendel Health Partner on Clinical Trial Matching Tech – GenomeWeb

NEW YORK (GenomeWeb) Cancer Genetics and Mendel Health announced today that they have formed a strategic alliance to combine their respective cancer clinical trial matching platforms.

Under the terms of the deal, the companies will incorporate Mendel's deep-learning engine called Mendel.ai in CGI's disease-focused reports and testing results. An initial version of the system is expected to be available to early-access partners in the second quarter of this year, with a wider rollout later in 2017, they said.

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Cancer Genetics, Mendel Health Partner on Clinical Trial Matching Tech - GenomeWeb

NewLink Genetics Corporation (NLNK) Plunges 9.96% on April 04 – Equities.com

Market Summary Follow

NewLink Genetics Corporation is a A biopharmaceutical company

NLNK - Market Data & News

NLNK - Stock Valuation Report

NewLink Genetics Corporation (NLNK) had a rough trading day for Tuesday April 04 as shares tumbled 9.96%, or a loss of $-2.3 per share, to close at $20.79. After opening the day at $19.46, shares of NewLink Genetics Corporation traded as high as $21.60 and as low as $16.39. Volume was 4.55 million shares over 25,830 trades, against an average daily volume of 322,298 shares and a total float of 29.22 million.

As a result of the decline, NewLink Genetics Corporation now has a market cap of $607.47 million. In the last year, shares of NewLink Genetics Corporation have traded between a range of $25.17 and $9.23, and its 50-day SMA is currently $17.14 and 200-day SMA is $13.04.

For a complete fundamental analysis of NewLink Genetics Corporation, check out Equities.coms Stock Valuation Analysis report for NLNK.

Want to invest with the experts? Subscribe to Equities Premium newsletters today! Visit http://www.equitiespremium.com/ to learn more about Guild Investments Market Commentary and Adam Sarhans Find Leading Stocks today.

NewLink Genetics Corp is a biopharmaceutical company. The Company is focused on discovering, developing and commercializing immunotherapeutic products to improve treatment options for patients with cancer.

NewLink Genetics Corporation is based out of Ames, IA and has some 122 employees. Its CEO is Charles J. Link.

NewLink Genetics Corporation is a component of the Russell 2000. The Russell 2000 is one of the leading indices tracking small-cap companies in the United States. It's maintained by Russell Investments, an industry leader in creating and maintaining indices, and consists of the smallest 2000 stocks from the broader Russell 3000 index.

Russell's indices differ from traditional indices like the Dow Jones Industrial Average (DJIA) or S&P 500, whose members are selected by committee, because they base membership entirely on an objective, rules based methodology. The 3,000 largest companies by market cap make up the Russell 3000, with the 2,000 smaller companies making up the Russell 2000. It's a simple approach that gives a broad, unbiased look at the small-cap market as a whole.

To get more information on NewLink Genetics Corporation and to follow the companys latest updates, you can visit the companys profile page here: NLNKs Profile. For more news on the financial markets and emerging growth companies, be sure to visit Equities.coms Newsdesk. Also, dont forget to sign-up for our daily email newsletter to ensure you dont miss out on any of our best stories.

All data provided by QuoteMedia and was accurate as of 4:30PM ET.

DISCLOSURE: The views and opinions expressed in this article are those of the authors, and do not represent the views of equities.com. Readers should not consider statements made by the author as formal recommendations and should consult their financial advisor before making any investment decisions. To read our full disclosure, please go to: http://www.equities.com/disclaimer

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NewLink Genetics Corporation (NLNK) Plunges 9.96% on April 04 - Equities.com

Students mother chicks – Shelby Star

Elise Franco Senior reporter efranco_star

For 21 days, students at Springmore Elementary gained hands-on experience caring for chicken eggs as a lesson in life cycles.

Wendy Turbyfill, youth development agent with 4-H of Cleveland County, said 4-H organized a school enrichment program and worked with Case Farms to have 125 eggs donated for use in five second-grade classrooms.

"The classes were studying life cycles, and embryology fit perfectly with this program," she said.

Second-grade teacher Anna Ramsey said the program not only taught students about life cycles, but also about responsibility.

"The kids were in charge of turning the eggs three times per day for 21 days in order for them to hatch," she said. "They were so excited, and they got so motherly, even the boys."

On Thursday, 4-H staff, along with Springmore students and teachers, wrapped up the project with a "chick birthday bash" to celebrate the hatching of 96 of the 125 eggs.

"You could ask any of the kids a question about the life cycle now, and they'll all be able to tell you about it," Ramsey said. "We love that they got the hands-on experience and got to take part in it."

Turbyfill said that hands-on learning is the reason why 4-H hosts these type of programs.

"They'd never understand how embryology works the way they do now," she said. "Hopefully it's something they'll always remember."

Turbyfill said 4-H has also worked this year with students at Bethware and Washington elementary schools. She said the goal is to eventually host the program in every second-grade class in Cleveland County.

Elise Franco can be reached at 704-669-3337 and efranco@shelbystar.com.

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Students mother chicks - Shelby Star

The Efficient Beauty of Starfish Larvae – Bay Nature

In the summer of 2015 three Stanford scientists took a class in embryology at Hopkins Marine Station in Pacific Grove and found themselves transfixed by a bat star larva that moved water around itself in swirling patterns. Using a microscope with video capacity, the scientists could see vortices of water slowly rotating, merging, and splitting apart around the millimeter-long larva.

We were totally surprised, says Vivek Prakash, a bioengineering postdoctoral scholar. They were so beautiful, and we were never expecting to see a really complex pattern of fluid flow around the starfish larvae, so that really got us hooked.

As the baby starfish waves its ciliathe small hairlike structures covering its bodythe water begins to swirl. The linear bands of cilia drape around its body like necklaces; its a common structure found across various types of aquatic invertebrate larvae.

But, the researchers wondered, Why would it be that all of these animals develop the same structure, this sort of way of stirring the water with these cilia? William Gilpin, an applied physics graduate student, recalls. By looking at the fluid dynamics, we think that we have an idea. Gilpin, Prakash, and bioengineering assistant professor Manu Prakash (no relation) detailed a potential evolutionary explanation in the December 2016 issue of Nature Physics.

The first two months of a bat stars life are spent floating through the ocean, constantly alternating between feeding and moving. And as the researchers found through observation and mathematical modeling, the ciliary bands are an ideal structure for maximizing the larvaes ability to do both. Algae particles pulled into the vortices swirl toward the larvas body, and once a particle touches the body, the cilia move it toward the larvas mouth. Meanwhile, the vortices also propel the tiny larvae through the ocean.

In their study, Gilpin, Prakash, and Prakash observed that the ciliary bands changed the patterns of vortices depending on the density of algae in the water around the larvae. If a larva sensed an abundance of food, then the ciliary bands could create more vortices to trap the food, while in lower-nutrient areas the ciliary bands would decrease the number of vortices for more efficient movement.

The complex dual-purpose action hadnt been observed before, Gilpin says. The starfish have found a new trick that we didnt know about; it was hiding right beneath our noses the entire time. Its always exciting to see that nature has found a solution that we havent.

After their larval stage, bat stars grow to an average diameter of eight inches and can be found in Bay Area tide pools.

Like this article? Help Bay Nature tell more stories about nature in the Bay Area Make a tax deductible donation to Bay Nature today!

by Eric Simons | March 20, 2017

If you look closely at the California Coast exhibit next time you visit the California Academy of Sciences, you'll see a bunch of small black sea snails. Are they there on purpose? Wildlife: Invertebrates, Reptiles, Amphibians

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The Efficient Beauty of Starfish Larvae - Bay Nature

Global Biochemistry Analyzers Market 2017- URIT Medical … – First Newshawk

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Global Biochemistry Analyzers Market 2017- URIT Medical ... - First Newshawk