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Research of Biochemistry Reagent Industry in Global and Chinese: Technology, Applications, Growth and Status 2017 – MilTech

The Global and Chinese Biochemistry Reagent Industry 2017 is a professional and in-depth study on the current state of the global Biochemistry Reagent industry with a focus on the Chinese market. The report provides key statistics on the market status of the Biochemistry Reagent market manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the industry

The report firstly reviews the basic information of Biochemistry Reagent market including its classification, application and manufacturing technology. The report then explores global and Chinas top manufacturers of Biochemistry Reagent market listing their product specification, capacity, Production value, and market share etc. The report further analyses quantitatively 2010-2015 global and Chinas total market of Biochemistry Reagent by calculation of main economic parameters of each company.

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The Global and Chinese Biochemistry Reagent Industry 2017 is a professional and in-depth study on the current state of the global Biochemistry Reagent industry with a focus on the Chinese market. The report provides key statistics on the market status of the Biochemistry Reagent market manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the industry

The report firstly reviews the basic information of Biochemistry Reagent market including its classification, application and manufacturing technology. The report then explores global and Chinas top manufacturers of Biochemistry Reagent market listing their product specification, capacity, Production value, and market share etc. The report further analyses quantitatively 2010-2015 global and Chinas total market of Biochemistry Reagent by calculation of main economic parameters of each company.

Have any query? ask our expert @ http://www.absolutereports.com/enquiry/pre-order-enquiry/10887137

Scope

Get a PDF Sample of Biochemistry Reagent Market Research Report at: http://www.absolutereports.com/enquiry/request-sample/10887137

Key Topics Covered:

Contact

Mr. Ameya Pingaley

Absolute Reports

+1-408 520 9750

Email sales@absolutereports.com

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Research of Biochemistry Reagent Industry in Global and Chinese: Technology, Applications, Growth and Status 2017 - MilTech

Self-assembling reagents with tunable colors and brightness enable … – Phys.Org

June 21, 2017 These fluorescence images show a matrix representing 124 distinct metafluorophores, that are generated by combining three fluorescent dyes with varying intensity levels. In the future, the metafluorophore's unique and identifiable color patterns can be used to analyze the molecular components of complex samples. Credit: Wyss Institute at Harvard University

Biomedical researchers are understanding the functions of molecules within the body's cells in ever greater detail by increasing the resolution of their microscopes. However, what's lagging behind is their ability to simultaneously visualize the many different molecules that mediate complex molecular processes in a single snap-shot.

Now, a team from Harvard's Wyss Institute for Biologically Inspired Engineering, the LMU Munich, and the Max Planck Institute of Biochemistry in Germany, has engineered highly versatile metafluorophores by integrating commonly used small fluorescent probes into self-folding DNA structures where their colors and brightness can be digitally programmed. This nanotechnological approach offers a palette of 124 virtual colors for microscopic imaging or other analytical methods that can be adapted in the future to visualize multiple molecular players at the same time with ultra-high definition. The method is reported in Science Advances.

With their new method, the researchers address the problem that thus far only a limited number of molecular species can be visualized simultaneously with fluorescence microscopy in a biological or clinical sample. By introducing fluorescent DNA nanostructures called metafluorophoresversatile fluorescent dyes whose colors are determined by how their individual components are arranged in 3-dimensional structuresthey overcome this bottleneck.

"We use DNA nanostructures as molecular pegboards: by functionalizing specific component strands at defined positions of the DNA nanostructure with one of three different fluorescent dyes, we achieve a broad spectrum of up to 124 fluorescent signals with unique color compositions and intensities," said Yin, who is a Core Faculty member at the Wyss Institute and Professor of Systems Biology at Harvard Medical School. "Our study provides a framework that allows researchers to construct a large collection of metafluorophores with digitally programmable optical properties that they can use to visualize multiple targets in the samples they are interested in."

The DNA nanostructure-based approach can be used like a barcoding system to visually profile the presence of many specific DNA or RNA sequences in samples in what is called multiplexing.

To enable the visualization of multiple molecular structures in tissue samples whose thickness can limit the movement of larger DNA nanostructures and make it difficult for them to find their targets, and to reduce the possibility that they attach themselves to non-specific targets producing false fluorescence signals, the team took additional engineering steps.

"We developed a triggered version of our metafluorophore that dynamically self-assembles from small component strands that take on their prescribed shape only when they bind their target," said Ralf Jungmann, Ph.D., who is faculty at the LMU Munich and the Max Planck Institute of Biochemistry and co-conducted the study together with Yin. "These in-situ assembled metafluorophores can not only be introduced into complex samples with similar combinatorial possibilities as the prefabricated ones to visualize DNA, but they could also be leveraged to label antibodies as widely used detection reagents for proteins and other biomolecules."

"This new type of programmable, microscopy-enhancing DNA nanotechnology reveals how work in the Wyss Institute's Molecular Robotics Initiative can invent new ways to solve long-standing problems in biology and medicine. These metafluorophores that can be programmed to self-assemble when they bind their target, and that have defined fluorescent barcode readouts, represent a new form of nanoscale devices that could help to reveal complex, multi-component, biological interactions that we know exist but have no way of studying today," said Wyss Founding Director Donald Ingber, M.D., Ph.D., who is also the Judah Folkman Professor of Vascular Biology at Harvard Medical School and the Vascular Biology Program at Boston Children's Hospital, and Professor of Bioengineering at the Harvard John A. Paulson School of Engineering and Applied Sciences.

Explore further: From super to ultra-resolution microscopy: New method pushes the frontier in imaging resolution

More information: "Sub100-nm metafluorophores with digitally tunable optical properties self-assembled from DNA" Science Advances (2017). advances.sciencemag.org/content/3/6/e1602128

Proteins mostly do not work in isolation but rather make up larger complexes like the molecular machines that enable cells to communicate with each other, move cargo around in their interiors or replicate their DNA. Our ability ...

Many biological and pathological processes are not strictly controlled by the presence, absence or function of biomolecules such as proteins or nucleic acids but rather by subtle changes in their numbers at specific locations ...

A new microscopy method could enable scientists to generate snapshots of dozens of different biomolecules at once in a single human cell, a team from the Wyss Institute of Biologically Inspired Engineering at Harvard University ...

A team at the Wyss Institute for Biologically Inspired Engineering at Harvard University has been awarded a special $3.5 million grant from the National Institutes of Health (NIH) to develop an inexpensive and easy-to-use ...

Much like the checkout clerk uses a machine that scans the barcodes on packages to identify what customers bought at the store, scientists use powerful microscopes and their own kinds of barcodes to help them identify various ...

Researchers at Columbia University have made a significant step toward breaking the so-called "color barrier" of light microscopy for biological systems, allowing for much more comprehensive, system-wide labeling and imaging ...

(Phys.org)A team of researchers at Universite Paris-Diderot has uncovered the reason for wobbling of wheeled suitcases. In their paper published in Proceedings of the Royal Society A, the group explains the physics behind ...

Biomedical researchers are understanding the functions of molecules within the body's cells in ever greater detail by increasing the resolution of their microscopes. However, what's lagging behind is their ability to simultaneously ...

There is a great deal of excitement around virtual reality (VR) headsets that display a computer-simulated world and augmented reality (AR) glasses that overlay computer-generated elements with the real world. Although AR ...

Researchers at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and Argonne National Laboratory have collaborated to design, build and test two devices that utilize different superconducting ...

Measurements at the Australian Centre for Neutron Scattering have helped clarify the arrangement of magnetic vortices, known as skyrmions, in manganese silicide (MnSi).

Hundreds of millions of pieces of space junk orbit the Earth daily, from chips of old rocket paint, to shards of solar panels, and entire dead satellites. This cloud of high-tech detritus whirls around the planet at about ...

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Self-assembling reagents with tunable colors and brightness enable ... - Phys.Org

Royal Court’s Anatomy of a Suicide deserves a prize for most obtuse script of the year – Spectator.co.uk

Anatomy of a Suicide looks at three generations of women in various phases of mental collapse. They line up on a stage that resembles a grey dungeon while sad events unfold around them. The first woman gets pregnant. The second takes heroin. The third argues with a lesbian about a fish. Their lives span several decades but their stories are presented simultaneously, and this tripartite method conceals the plain fact that the events dramatised are too flimsy to merit theatrical portrayal. A soap opera would baulk at such scenes: a druggie teenager bores a cameraman with a list of gloomy soundbites; a female wedding guest is partially seduced by a giggling gatecrasher; a patient in a hospital invites a nurse to eat some haddock.

Writer Alice Birch aims her characterisation at the chicklit crowd. All the females are sympathetic because theyre lost, miserable and a bit whiney. The males are uniformly horrible, aggressive, sentimental boors. With one exception: a black male character who seems so sweet and intelligent that he might be an honorary woman. Each change of scene involves a flash of lesbian titillation. The actresses are stripped to their bikinis by stage hands who pass them fresh costumes to climb into. Some scenes end with a massive CRUMP! and a surge of lights as if to remind us that a momentous art work is in progress. And the actors move to their new positions in super-slow motion, which gives a strong hint that This Play Deserves A Prize. It does, in a way, deserve a prize for the most obtuse script of the year.

The dialogue has been crafted as an act of sabotage. Rather than editing and refining normal conversation to give it tension, shape and direction, Ms Birch has retained all the banal and pointless detritus of everyday speech. This trick is perfectly easy to accomplish if you have copious quantities of stage time to fill and nothing significant to say. Both conditions are met here. One wonders why the actors agreed to participate in a show that demeans their artistry and sets out, quite deliberately, to discover how thoroughly an audience can be demoralised within a two-hour timescale. And although the production takes itself very seriously, it fails to extend the same courtesy to mental illness. Suicide is treated as one of those things that sort of, you know, kind of happens, like rheumatism or bad teeth. Of the three main characters, two kill themselves and the third seeks a surgeon who can cut out her ovaries for her, as if infertility were the pathway to happiness. Anyone with mental-health problems should avoid this play. It discusses various life-ending techniques and demonstrates one of them on stage. How odd of the Royal Court to create an ode to extinction and a hymn to self-slaughter. If Isis had an Arts Council, this would be among its proudest commissions.

Emma Rices subtle, clever and fabulously entertaining show, Tristan and Yseult, opens with a chorus of anoraked nerds identifying themselves as the love-spotters. They belong to The Club of the Unloved and the title is spelled out for us in vivid neon lights. Perhaps this is a sly dig at the Globes management, which is said to have lost patience with Ms Rices taste for modern dress, stage lights and electrical instruments played live. But why? This show is a triumphant blend of fun, jokes, pop tunes and satirical slapstick.

Only a couple of drawbacks. The story is short of detailed incident and the three lead actors are not the companys best strengths. Mike Shepherd is too solemn as King Mark. Yseult, played by Hannah Vassallo, relies too much on her giggly smile and Dominic Marshs Tristan is short of energy and grandeur. This leaves a vacuum which the minor players rush to fill. Kyle Lima (Frocin) is an exceptional clown with a wonderfully bendy physique. He may be slim and handsome (both are drawbacks for a physical comic), but he has a terrific way of parading his sexual charisma while parodying it at the same time. Kirsty Woodward, as Whitehands, shimmies around the stage in a Jackie-O outfit making sardonic comments on the action. Best of all is Niall Ashdown as Yseults cross-dressing maid, Brangian. His comic gift is matched by his absolute mastery of the crowd.

The building itself helps, of course. In some mysterious way the Globes atmosphere seems to combine the riotous air of a cup final with the warmth and intimacy of a pub gig. Emma Rice will be a hard act to follow. Her experiments with music, lighting and on-stage acrobatics have stopped the Globe from becoming a museum, or even a mausoleum, of Shakespeare. The snag is that we have only one Globe to play with. Lets build a replica, dedicate it to musical theatre, and put the newly elevated Dame Emma in charge.

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Royal Court's Anatomy of a Suicide deserves a prize for most obtuse script of the year - Spectator.co.uk

Grey’s Anatomy is bringing back classic character Dr Teddy Altman in season 14 – DigitalSpy.com

Grey's Anatomy is bringing back a fan favourite for season 14.

Deadline reports that Kim Raver will return to the ABC medical drama as Dr Teddy Altman for a guest arc on the upcoming season, although it's not yet clear what her storyline will be.

Dr Altman was last seen in the season eight finale when she was fired from Seattle Grace by her crush Owen Hunt (Kevin McKidd) for a good reason as it allowed her to take her dream job at MEDCOM.

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It wasn't the last we heard of her though, as Amelia (Caterina Scorsone) spoke to her on the phone in season 13 when Owen's presumed dead sister was treated at Altman's hospital.

Raver will also be seen in the fifth season of Ray Donovan in a recurring role as a surgeon.

Grey's Anatomy fans were left relieved, but sad, when the season 13 finale last month saw series regular Jerrika Hinton leave her role as Dr Stephanie Edwards after five seasons on the show.

Kelsey McNeal/ABC via Getty Images

The dramatic season finale saw Dr Edwards perform surgery on the leg of a young girl as they attempted to escape a fire at Grey Sloan, with the ordeal leaving them alive but shaking Stephanie so much that she quit her job.

Grey's Anatomy airs on ABC in the US and Sky Living in the UK.

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Grey's Anatomy is bringing back classic character Dr Teddy Altman in season 14 - DigitalSpy.com

Three ways neuroscience can advance the concussion debate – Medical Xpress

June 21, 2017 Credit: CC0 Public Domain

While concussion awareness has improved over the past decade, understanding the nuances of these sports injuries, their severity, symptoms, and treatment, is still a work in progress. In the June 21 issue of Neuron, UCLA neurologists and neurotraumatologists review the science of concussions and outline several areas where neuroscience and clinical research can help create consensus in the field: definitions of what acute and chronic concussions are, diagnostics, and management and treatment.

"For patients, you have to be able to provide the best care even if you don't have the exact research study to prove what you're doing, and you also have to address the information that the patients and their families are getting through the media," says Christopher C. Giza (@griz1), Director of the UCLA Steve Tisch BrainSPORT program and Professor of Pediatrics, Neurology, and Neurosurgery at the University of California Los Angeles. "That's a discussion that's hard to have because people naturally look for very short answers and sound biytes, and it's far more complex than that."

1. Let's Agree on the Definition of a "Concussion," both Acute and Chronic

The Centers for Disease Control and Prevention reported about 2.8 million traumatic-brain-injury-related emergency department visits, hospitalizations, and deaths in the United States in 2013. However, researchers disagree about whether all concussions and traumatic brain injuries are equal. A concussion may be characterized by wooziness, disorientation, incoordination, headache, and other "typical" symptoms after a hit to the head and may occur even with only rapid back-and-forth motion of the head and neck. Some have postulated that subconcussive injuries with repetitive head impacts in the absence of symptoms may result in cumulative problems.

Giza says that although a concussion and a more severe traumatic brain injury may sound similar, and although they may share some symptoms, the overlap between the two is not clear. Additionally, the determination of whether someone has a concussion or a mild traumatic brain injury or something else is largely subjective and often relies heavily on symptom reporting from the patient.

"One of the things that will help us on the acute diagnosis of concussion would be if we moved away from the current understanding of concussion as a black-or-white, yes-or-no answer," Giza says. "There are scenarios when we can be more certain, clinically, that we're making the correct diagnosis. If there's a clear impact event, there's a typical constellation of symptoms that occurs in temporal relationship to the impact, and that symptom pattern has a time course consistent with what we see in concussion in terms of peaking early followed by gradual improvement, then we can diagnose confidently."

Giza notes that not every symptom that occurs after a hit to the head is related to a concussion, which is why formal diagnosis requires an experienced clinician. Similarly, not all chronic symptoms are referable to a distant concussion or head impact. Understanding the physiological mechanisms underlying concussions and concussive symptoms (both acute and chronic) can lead to better diagnostic tests and potentially point the way to individualized treatment plans.

2. Realize that Diagnosis Is Critical to Treatment

Some concussion patients experience atypical symptoms, or usual symptoms that get worse later on instead of improving. One potential pitfall of concussion diagnosis is that some symptoms may appear to be concussion related but could actually be a symptom of something else, like migraine, dehydration, hyperthermia, neck strain, or more severe brain injury.

"We need to prioritize what we think sounds like a definite concussion vs. probable vs. possible, and even recognize that there are syndromes with neurological symptoms that occur after impact that are something more than a concussion," Giza says. "There are rare patients who have cerebral edemasometimes, we call it second impact syndrome, which is another ambiguous termbut that's not a concussion. Patients who very rarely get a subdural hematoma as a consequence of a sports injury sometimes are portrayed as having had a concussion, but a subdural hematoma or an epidural hematoma is something much more than what we would diagnose clinically as a concussion."

There are also computerized tests, and soon, hopefully blood tests, brain imaging, and electrical tests that can help diagnose concussion or follow recovery, but because concussions are "the most complex injury to the most complex organ" in the human body, there is not necessarily a magic bullet, catch-all, perfect method for diagnosing concussions.

3. Focus on Animal Research to Discover Better Treatment Plans

"In the clinical concussion world, many of the research protocols are observational, but I think laboratory neuroscience can inform in terms of how important is the time between injuries and how much cognitive or physical activity should there be during the recovery period," Giza says. Focusing on animal models is one way neuroscience can help accelerate concussion and traumatic brain injury research, particularly in the investigation of how consequences of repetitive injury differ when they occur very close in time versus when they are spaced out, and in determining when the brain is physiologically ready to return to activity.

"Animal models are also well suited for looking at long-term processes set into play by the acute injury." Giza says. "So animals can be subjected to repetitive injuries when they're relatively youngat least in rodent models, within a year or two, those animals become 'old' animals, and we can look to see along that time course whether mechanisms of neurodegeneration have been activated, and whether that leads to deficits over time. Those studies can be done in the time course of months to years rather than decades, as would be necessary for clinical studies. If we do things right in the coming years, we can really change the game in our understanding about concussion and brain injuries."

Explore further: Athletes may have white matter brain changes six months after a concussion

More information: Neuron, Giza et al: "It's Not All Fun & Games: Sports, Concussions and Neuroscience" http://www.cell.com/neuron/fulltext/S0896-6273(17)30404-X , DOI: 10.1016/j.neuron.2017.05.003

Journal reference: Neuron

Provided by: Cell Press

New research finds white matter changes in the brains of athletes six months after a concussion. The study will be presented at the Sports Concussion Conference in Chicago, July 8-10, hosted by the American Academy of Neurology, ...

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Nearly half of female athletes participating in high school sports have had a diagnosed or suspected concussionbut most don't report these sports-related injuries to coaches or trainers, reports a study in the Journal ...

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(HealthDay)Athletes may take longer to recover after a concussion if they had psychosomatic symptomsaches and pains caused by mental distressbefore their head injury, new research suggests.

Although "multitasking" is a popular buzzword, research shows that only 2% of the population actually multitasks efficiently. Most of us just shift back and forth between different tasks, a process that requires our brains ...

While concussion awareness has improved over the past decade, understanding the nuances of these sports injuries, their severity, symptoms, and treatment, is still a work in progress. In the June 21 issue of Neuron, UCLA ...

For most people having a good memory means being able to remember more information clearly for long periods of time. For neuroscientists too, the inability to remember was long believed to represent a failure of the brain's ...

The optic nerve is vital for visiondamage to this critical structure can lead to severe and irreversible loss of vision. Fengfeng Bei, PhD, a principal investigator in the Department of Neurosurgery at Brigham and Women's ...

An international research team led by investigators at Massachusetts General Hospital (MGH) and the University of California at Los Angeles (UCLA) - along with their facilitating partner the Tourette Association of America ...

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Three ways neuroscience can advance the concussion debate - Medical Xpress

What’s in Celgene’s Immunology and Inflammation Clinical Pipeline? – Market Realist

These Drugs Could Drive Celgene's Growth in 2017 PART 5 OF 8

Celgenes (CELG) Ozanimod is a selective S1P 1 and S1P 5 modulator. Data from phase three trial SUNBEAMhas demonstrated the efficacy and safety of Ozanimod as a treatment option for patients suffering from relapsing multiple sclerosis. In May 2017, Celgene (CELG) announced its success in the second pivotal (RADIANCE) phase three trial. The RADIANCE trial aimed to evaluate the safety and efficacy of Ozanimod in relapsing multiple sclerosis patients. The primary endpoint of the RADIANCE study was to reduce the annualized relapse rate (or ARR). Ozanimod demonstrated a significant reduction in ARR.

The company expects to start several pivotal trials in 2017. After the success of ozanimod in the STEPSTONE phase two trial, the company may begin phase three trials for the evaluation of the drug as a treatment for Crohns disease.

The above table indicates Celgenes different ongoing trials in inflammation, immunology, and cellular therapies.

After the success of Otezla in the marketplace, Celgene has started various other trials on the drug for label expansion in areas such as atopic dermatitis, ulcerative colitis, and ankylosing spondylitis.

Celgene has entered a strategic collaboration with Acceleron for the development of luspatercept. The drug is being investigated in phase three trials, MEDALIST and BELIEVE, to evaluate its efficacy as a therapy option for patients suffering from myelodysplastic syndromes and beta-thalassemia, respectively.

Celgene has started a pivotal trial to study investigational therapy GED-301 for Crohns disease, while the phase two trial for the drug in ulcerative colitis indications is expected to conclude by mid-2017. The company anticipates that ozanimod and GED-301 may turn out to be future blockbuster drugs. Celgenes revenue growth may boost the share prices of the Vanguard Health Care ETF (VHT). Celgene makes up about 2.7% of VHTs total portfolio holdings.

Celgenes peers in the inflammation and immunology drug market include Johnson & Johnson (JNJ), Amgen (AMGN), AbbVie (ABBV), and Novartis.

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What's in Celgene's Immunology and Inflammation Clinical Pipeline? - Market Realist

Global Immunology Drugs Market 2017-2022 – mAbs Market Expected to Experience Continued Growth from $57.7 … – PR Newswire (press release)

The report Global Immunology Drugs Market to 2022 - Increasing Prevalence, Repositioning Opportunities and Strong Uptake of Interleukin Receptor Inhibitors to Drive Growth focuses on four key indications within immunology: Rheumatoid arthritis, Systemic lupus erythematosus (SLE), Psoriasis and Inflammatory bowel disease.

Although the patents for many of these mAbs have either already expired or are due to expire during the forecast period, the market is expected to experience continued growth, from $57.7 billion in 2015 to $75.4 billion in 2022, at a compound annual growth rate (CAGR) of 3.88%.

This is due to practical and regulatory barriers to entry for biosimilars that are not present for small molecule generics, and a moderately strong late-stage pipeline. There is a large pharmaceutical pipeline for immunology, consisting of 2,054 products in active development. The majority of pipeline products (73%) are in the early stages of development, at either the Preclinical or Discovery stages, but 96 (5%) are in Phase III.

The key market players, namely AbbVie, Johnson & Johnson, Roche, Amgen and Pfizer, are forecast to maintain their strong market shares throughout the forecast period, despite the fact that many of the approaching patent expiries - especially that of adalimumab, marketed by AbbVie, and Remicade, marketed by Johnson & Johnson - will affect these companies directly.

Key Topics Covered:

1 Introduction

2 Key Marketed Products

3 Pipeline Landscape Assessment

4 Multi-scenario Market Forecast to 2022

5 Company Analysis and Positioning

6 Strategic Consolidations

7 Appendix

For more information about this report visit https://www.researchandmarkets.com/research/kv7xk5/global_immunology

Media Contact:

Research and Markets Laura Wood, Senior Manager press@researchandmarkets.com

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To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/global-immunology-drugs-market-2017-2022---mabs-market-expected-to-experience-continued-growth-from-577-billion-in-2015-to-754-billion-in-2022-at-a-cagr-of-388---research-and-markets-300477452.html

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Global Immunology Drugs Market 2017-2022 - mAbs Market Expected to Experience Continued Growth from $57.7 ... - PR Newswire (press release)

Would Rachel Brand Stand Up to Trump? – Newsweek

This article first appeared on the Just Security site.

Last week, amid speculation that Acting Attorney General Rod Rosenstein may be forced to recuse himself from the expanding Russia investigation unless he gets fired first attention focused on the next in line: Associate Attorney General Rachel Brand.

Brand, it should be noted, has had a more obviously partisan career than Rosenstein, and the burning question seems to be whether she has the gumption or the will to stand up to the President if he tries to derail the investigation, for example by trying to fire Special Counsel Robert Mueller. (This is not to say Trump has the authority to fire Mueller Marty Lederman argues that he doesnt.)

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Does Brand have what it takes? Jack Goldsmith and Ben Wittes, both of whom know her well, affirm that she does and describe her as intelligent, fair, independent, and tough-minded.

My own answer to the question Who is Rachel Brand? is: it doesnt much matter. Its simply a mistake to focus on individual personality to predict how someone will act. Social psychologists have a long-standing name for this mistake: they call it the fundamental attribution error. Thats the error of explaining human behavior by individual character and personality traits.

The situation in which we find ourselves matters crucially, often invisibly, and to a far greater degree than common sense would suggest. This is a lesson we might apply not only to Brand, but also to Lt. Gen. H.R. McMaster and other souls in this administration.

Rachel Brand, Associate Attorney General, testifies before the Senate Judiciary Committee on Capitol Hill in Washington March 7, 2017. Aaron P. Bernstein/reuters

A bit of background:

In a classic 1972 experiment, a person coming out of a phone booth sees a woman spill her folder full of papers on the shopping mall floor a few feet away. (She is part of the experimental team, and she spills them on purpose.)

Will subjects help her pick up the papers?

Among one group of subjects, the answer was overwhelmingly yes: fourteen people helped and only two did not. In a second group, it was overwhelmingly no. Only one subject helped; the other 24 walked away.

What explains the difference? Something amazingly small: Those in the first group had found a dime in the telephones coin return, which apparently put them in a benevolent mood.

Those in the second group found no dime, and they stepped around the spilled papers and went their not-so-merry way. A trivial and nearly invisible manipulation of the situation led to a dramatic change in outcomes.

According to the situationist school of psychology, this experiment (along with many others, including the famous Milgram obedience experiment and the Stanford Prison Experiment) shows that we deceive ourselves when we think character is the crucial determinant of how we behave.

In the Stanford experiment, one subject who described himself as a non-violent person and pacifist transformed into a brutal prison guard in a matter of days. Which was he, a self-deceiving brute in pacifists clothes, or a sensitive soul who forgot himself?

Neither one, according to the situationists. Look to the situation, not to the person. He was a prison guard, and as he explained in his diary (reproduced in a write up of the psychology experiment), This new prisoner, 416, refuses to eat. That is a violation of Rule Two and we are not going to have any of that kind of shit. I decide to force feed him. I let the food slide down his face. I dont believe it is me doing it.

For the situationists, there is nothing unbelievable about it, because the me who does it is not a constant.

This seems wildly counterintuitive, because we always think about peoples character, their virtues and vices. Isnt there a difference between a brave person and a coward?

Not necessarily, according to philosopher John Doris. In a pioneering 2002 book, Doris writes:

Its not crazy to think that someone could be courageous in physical but not moral extremity, or be moderate with food but not sex, or be honest with spouses but not with taxes. With a bit of effort, we can imagine someone showing physical courage on the battlefield, but cowering in the face of storms, heights, or wild animals. Things can get still trickier: Someone might exhibit battlefield courage in the face of rifle fire but not in the face of artillery fire. (Lack of Character: Personality and Moral Behavior, p. 62.)

Doriss point: there is no such thing as courage across the board. Courage, like every other character trait, can be entirely situation-specific. If that seems contrary to everyday experience, its because most of us, most of the time, live in the same situation from one day to the next: we see the same family and friends today that we saw yesterday and will see tomorrow; we live in the same locale for months or years at a time, and if were employed we work at the same job.

Of course, not even the most radical situationists think individual personality is irrelevant to the choices we make. Talk about the fundamental attribution error does not deny free will or individual differences, or assert that only situations matter, one hundred percent.

Rather, the error lies in vastly overestimating character and ignoring the hidden power of the situation which we do all the time, not least when we play the blame game in criminal sentencing. (I heartily recommend the powerful podcast The Personality Myth, especially its second episode.)

My wife sometimes teaches college philosophy in a prison, where many of her students committed crimes of violence. In the classroom setting, she finds them no different from other college students, and she feels no less safe in their company.

For years, psychologists debated which variable matters more, person or situation; some tried to quantify it. Like many academic debates, this one was technically intricate and personally acrimonious in the words of psychologist John Kihlstrom, it ended up looking more like a fight in an elementary schoolyard.

Over the years, psychologists began to look beyond the sharp either/or, and instead study the way that person and situation influence each other. (In the jargon, this is person/situation interactionism.)

To take a simple example: people behave differently toward a baby depending on whether theyre told the baby is a girl or a boy. The person (the baby) transforms the situation he or she is in (in this case, the way people treat the baby). And vice-versa: how people treat girls and boys as they grow up affects the person they become.

On this line of thought, whenever you enter a room full of people, you become part of the situation of the other people in the room. You change how the others behave; they become part of your situation, and influence how you behave. Thats interactionism. The theory has been around for decades, since the pioneering work of psychologist Kurt Lewin and sociologist Erving Goffman.

Enough of the theory. What it means for the Russia investigation is straightforward: its a mistake to ask who Rachel Brand is, because there is no is. To think otherwise is the fundamental attribution error.

When she decided to join the Trump administration and the Jeff Sessions Justice Department, Brand radically changed her situation. Specifically, she overcame whatever qualms she may have felt about Trump, qualms shared by many conservatives. (After the election, I posted on why those qualms are justified.)

Eyes wide open, she joined an administration that puts a premium on personal loyalty to a narcissistic president who takes everything personally. She placed herself in an environment where the abnormal is the new normal.

Its hard to believe she did it with the intention of slowing down the presidents hectic velocity her background is, as Eric Levitz writes, a bit more partisan and decidedly more right-wing than Rosensteins. Precisely if she is a person who takes her commitments seriously, signing on to the Trump team is a loyalty commitment that, day in and day out, will challenge her commitment to the rule of law. Neither past behavior nor perceived character can predict how she will manage that challenge. If the psychologists are right, she cannot predict it herself.

In my earlier essay on serving in the Trump administration, I warned that

Once you are inside, your frame of reference changes. You see that many of the people youre working with are decent and likable. You tell yourself that decent people like these wouldnt do anything indecent. And above all, you reassure yourself of your own decency because you can contrast yourself with the real radicals, the true believers. Theyre right down the hall.

It doesnt matter if you are what moralists of my generation like to call a person of integrity a person whose principles harmonize with her conduct. Years ago, in the wake of the Enron-era corporate scandals, the law school and business school worlds endured a predictable outbreak of academic conferences on integrity.

Churlishly, I pointed out that you can harmonize your principles and your conduct by changing your principles just as easily as by changing your conduct. That too is one of the basic teachings of social psychology: we often reduce cognitive dissonance between our principles and our conduct the easy way, by unconsciously modifying our principles so they rationalize our conduct.

Of course it is comforting to know that a public official is an admirable person and not an opportunist or a scoundrel. But blind faith that persons of character will rescue us is faith in an illusion. Look to the situation, not to the person.

David Luban is Professor in Law and Philosophy at Georgetown University.

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Would Rachel Brand Stand Up to Trump? - Newsweek

Technology is created for the purpose of augmenting the fundamental weaknesses of human beings – Recode

A version of this essay was originally published at Tech.pinions, a website dedicated to informed opinions, insight and perspective on the tech industry.

One of the core premises of our research is to understand technology from a deeper human level. We too often get caught up in the technology itself, and may lose sight of the basic human needs or desires technology is serving. With all the tech of artificial intelligence, augmented reality and any number of other buzzwords, I sense that the human angle is again being lost while we chase technological advancements for the sake of the technology rather than the sake of the human.

The human angle is being lost while we chase technological advancements for the sake of the technology rather than the sake of the human.

To frame my perspective, I think it is helpful to use the idea of human augmentation as a basis for our understanding of how technology serves humans and will always do so. The core definition of augment is to make something greater by adding to it. Using this framework from a historical perspective, we can observe how nearly every human technological invention was designed to augment a fundamental weakness of human beings.

Tools were invented to augment our hands so we can build faster, bigger, more complex things. Cars were invented to augment the limitations of the distance humans can travel. Planes were invented to augment humans lack of ability to fly. The telephone was invented to augment the limitations of human communications. Nearly every example of technological innovation we can think of had something to do with extending or making greater some aspect of a human limitation or weakness.

This was true of historical innovation, and it will be true of future innovation, as well. Everything we invent in the future will find a home augmenting some shortcoming of our human bodies. Technology, at its best, will extend human capabilities and allow us to do things we could not do before.

While we can analyze many different angles in which technology will augment our human abilities, there is one I think may be one of the more compelling things to augment: Our memory.

My family and I recently took a vacation to Maui. It is always nice to get out of the bubble of Silicon Valley for a more natural atmosphere to observe human behavior and technology. Going to a place where most people are on vacation provides an even deeper atmospheric layer to observe.

One of technologys greatest values to humans is in the assistance of capturing memories.

On vacation, I saw how critical and transformative the smartphone camera has been when it comes to memory augmentation. Ive long thought that one of technologys greatest values to humans is in the assistance of capturing memories. For sure, this is the single driving motivation behind most people purchasing digital cameras and video cameras through the years. With most people in developed markets now owning a memory-capture device, and comparable apps on their smartphones to enhance these memories, observing memory augmentation is now a frequent activity.

It was fascinating to see the lengths people on vacation would go through with their phones, drones (I was surprised how many drones I saw), GoPros, waterproof smartphone cases and more to capture and preserve their memories.

I saw people climbing trees, braving cliffs and hiking extreme conditions with their phones to get a unique selfie. Flying their drone overhead as they jumped off waterfalls. Putting their phones in waterproof cases to get pics of kids snorkeling. And obviously, there were lots of uses for GoPros to capture unique photos and videos of undersea creatures and experiences.

The camera sensor is, and will remain for some time, one of the most important parts of our mobile computing capabilities.

As was often the case, most of the memories captured are designed to share on social media, but the point remains that these pervasive capture devices enable us to create and capture memories we would most likely forget, or have a hard time recalling if left to our memory.

Ive argued before that the camera sensor is, and will remain for some time, one of the most important parts of our mobile computing capabilities. The desire to preserve, or capture a unique memory will remain a deeply emotional and powerful motivator for humans.

Allowing technology to take this idea a step further, we have things like Apple Photos and Google Photos, which look over our memories and make short videos to not just augment but to automate our memory creation process. As machine learning gets even better, these technologies will make creating memories from moments even easier.

As technology continues to augment more and more of our human capabilities, my hope is that the technological tool or process involved will fade so deeply into the background that it nearly disappears. This way we can get the most out of our time whether at work, school, play or vacation, and spend less time fidgeting with technology. Ultimately we will be able to do more with technology, but also spend less time with the technology itself, and more time doing the things we love.

Ben Bajarin is a principal analyst at Creative Strategies Inc., an industry analysis, market intelligence and research firm located in Silicon Valley. His primary focus is consumer technology and market trend research. He is a husband, father, gadget enthusiast, trend spotter, early adopter and hobby farmer. Reach him @BenBajarin.

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Technology is created for the purpose of augmenting the fundamental weaknesses of human beings - Recode

Apes Have Social Traditions Just Like Humans, Chimp Behavior Shows – International Business Times

Chimpanzees want to fit in with the popular kids, just like humans do researchers say chimps will change their behavior to match what others are doing.

A study in the journal Current Biology points to a specific type of behavior in these apes called the grooming handclasp. Its exactly what it sounds like: Two animals engaged in the social interaction of grooming will clasp one anothers hands. But the exact form this rare chimp handshake varies among groups, with some gripping each others palms and the others gripping wrists depending on what group they were in. Scientists studying the behavior in Zambia saidits a group-level cultural tradition in chimpanzees rather than one passed down from mothers to their young.

Read: What Monkey Brains and Social Behavior Tell Us About Human Minds

Grooming itself is a social behavior that does more than clean the chimps: It is also a bonding experience, a way to relax and an action that defers to the hierarchy of the chimp community. And only some groups of these apes perform the handclasp. The University of St. Andrews explained that because it varies among groups as opposed to chimpanzee families, this indicates that, like humans, chimpanzees have the capacity and motivation to learn from each other and fine tune their learned behavior such that it matches with the group norm.

A behavior passed down through a family line does not explain why chimps within one group will clasp hands in one way and chimps in another will clasp in another.

Some chimpanzees clasp hands while grooming, a behavior they acquire in groups rather than learn from their families. The behaviors origin shows chimps can form and adhere to cultures just like humans. Photo: University of St. Andrews

It is hard to imagine how any genetic or environmental influences could have shaped the group-specific preferences that we observed, lead author Edwin van Leeuwen said in the statement. Within the group chimpanzees converged on one particular variant of clasping. This indicates a certain willingness to match each others styles.

The study offers a glimpse into the minds of chimps, specifically whether they can form a culture and cultural traditions, which is a controversial topic. The university said becausechimpanzees can form a social tradition like a grooming handclasp behavior outside of their family unit,they are more closely mimicking human culture than previously thought.

Read: Jungle Falls Silent After Howler Monkey Disease Epidemic

Although chimpanzees are different from humans in many ways, they are similar in others. For one, the genetic differences between the species are miniscule: Humans and chimps share almost 99 percent of their DNA. Chimpanzees can use tools to get a job done, and its possible that they can live as long as humans in the wild recent research has shown if disease, food shortages, predators or other hazards dont get in the way, a chimpanzee can live almost 33 years. Thats right within the range of life expectancy for those who have similar lifestyles to apes, the human hunter-gatherers still left in the world. Those people live27 to 37 years.

Understanding the relationship between humans and chimpanzees isnt just a point of interest. It can also help scientists understand how humans evolved and, in the case of life expectancy, how different conditions changed mortality rates.

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Apes Have Social Traditions Just Like Humans, Chimp Behavior Shows - International Business Times