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Student highlight – NDSU The Spectrum

An undergrad creating new chemicals to better humans environmental output

Walking around Dunbar Hall I was looking to pull aside a student to interview. Luckily, chemistry student Timothy Burns was available for me to talk to.

Q: To begin, whereare you from?

A: Im from Hudson, Wisconsin.

Q: If youre fromWisconsin, what made you choose NDSU?

A: I choose NDSU because it had a lot of affordable opportunitiesas a research land grant university. I thought it seemed like a great fit.

Q: Whats your major?

A: Im a chemistry major.

Q: Oh nice, are youinvolved in anything on campus?

A: Im the vice president of the Chemistry Club.

Q: What does it mean to be the vice president of the Chemistry Club?

A: It means that I have the opportunity to give back to the chemistry department. I help to organize and inform chemistry and biochemistry students about professional opportunities to help them with their career goals.

Q: What is your favorite thing about being an NDSU student? And in your own words, what does it mean to be a Bison?

A: I enjoy the community, I like that NDSU is a small(er) campus.I also like that the chemistry department is small, so I can make more valuableconnections with other students and my professors.

To be a Bison is to be a leader. To contribute to the community and campus. A Bison is hardworking and driven and doesnt back away from a challenge.

Q: I love that. What is something specific the Chemistry Club does to help students?

A: The Chemistry Club funds student trips to the annual American Chemistry Society Conference (or ACSC), a conference for students to learn more about chemistry research. As well as to showcase their own research.

Q: That sounds cool,have you been to the annual American Chemistry Society Conference?

A: No, but I am going this year at the end of March. I will be doing a poster presentation about my undergraduate research that Ive been working on for nine months.

Q: What is yourresearch?

A: Developing new chemicals that can be used to makedifferent plastics and coating materials. In making new compounds we couldreplace the current compounds, making plastic that is better for theenvironment.

Thank you, Timothy, for your time.

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Student highlight - NDSU The Spectrum

Resolution Bioscience and LabCorp Will Collaborate to Commercialize the Resolution ctDx Lung Liquid Biopsy Assay – BioSpace

Feb. 24, 2020 13:00 UTC

Resolution ctDx Lung assay has a demonstrated ability to provide clinically actionable results that can inform care decisions for NSCLC patients

KIRKLAND, Wash.--(BUSINESS WIRE)-- Resolution Bioscience, Inc., today announced an agreement with LabCorp (NYSE: LH), a leading global life sciences company that is deeply integrated in guiding patient care, to make the Resolution ctDx Lung assay available to clinicians and patients. The fast, accurate, and non-invasive test is designed to detect actionable mutations in non-small cell lung cancer (NSCLC) genes recommended by professional guidelines. The assay will be performed in Resolutions CLIA laboratory as a laboratory developed test, and is expected to be available exclusively from LabCorp in the first half of 2020.

The clinical utility of the Resolution ctDx Lung assay has been successfully demonstrated in multiple clinical studies with leading cancer centers and academic research institutions, including Memorial Sloan Kettering Cancer Center, Northern Cancer Institute of Sydney, Dana-Farber Cancer Institute, and Vanderbilt University.

We are excited to be working with LabCorp to enable broad access to our ctDx Lung assay, said Mark Li, CEO of Resolution Bioscience. With our purpose-built cell-free DNA technology platform, we look forward to making a clinically meaningful impact for a growing number of patients.

About Resolution Biosciences Liquid Biopsy Technology

The Resolution liquid biopsy assays are powered by the companys patented cell-free DNA (cfDNA) analysis platform, which includes proprietary targeted capture next-generation sequencing (NGS) biochemistry and tightly coupled, cloud-based bioinformatics. Resolutions technology has now been recognized as novel by the FDA and has been cited in several important scientific publications and presentations. For example:

About Resolution Bioscience

Resolution Bioscience is a privately held company dedicated to developing a highly sensitive, non-invasive liquid biopsy platform that improves cancer diagnostics and monitoring for patients around the world. The company has developed and patented core technology for circulating cell-free DNA NGS analysis. The company is based in Kirkland, Wash. For more information, visit http://www.resolutionbio.com.

Resolution Bioscience, the Resolution Bioscience logo, and ctDx Lung are trademarks of Resolution Bioscience, Inc. All other brands may be trademarks of their respective holders.

View source version on businesswire.com: https://www.businesswire.com/news/home/20200224005448/en/

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Resolution Bioscience and LabCorp Will Collaborate to Commercialize the Resolution ctDx Lung Liquid Biopsy Assay - BioSpace

AB Professor named topic editor of journal | News, Sports, Jobs – The Inter-Mountain

PHILIPPI Alderson Broaddus Universitys Dr. Yi Charlie Chen, professor of biology in the College of Health, Science, Technology & Mathematics, has been named topic editor of the Multidisciplinary Digital Publishing Institute (MDPI) open-access journal Cancers.

An international, peer-reviewed open access journal, Cancers aims to encourage scientists to publish papers, reviews, editorials, communications, and more regarding experimental and theoretical research results. Cancers received a Journal Impact Factor-the standard proxy for the relative importance of a journal within its field-of 6.126 in 2019 by the Journal Citation Reports and now ranks 31/229 (Q1) in the category Oncology.

As a scientist and educator, I serve the scientific world, said Dr. Chen. MDPI provides a space where scientists from a wide range of backgrounds can identify a matter of common interest and concern. It is an honor and a privilege to be a part of this publications mission.

In 2015, Dr. Chen was named editor-in-chief for ClinMed International Librarys Journal of Nutritional Medicine and Diet Care(JNMDC), an archive of nutritional information that serves the global scientific community. Additionally, Chen serves as an editorial board member for the Journal of Biochemistry and Molecular Biology Research, International Archives of Clinical Pharmacology, and many more.

Science and technology are constantly changing and evolving, explained Dr. Chen. Resources like the Journal of Nutritional Medicine and Diet Care and Cancers are designed to create an archive of scientific discovery and knowledge, both positive and negative.

Dr. Chen has received many accolades throughout his career. Alongside Dr. Ivan Martinez of WVU School of Medicine, Dr. Chen was awarded $100,000 by WV-INBRE to continue his research in the field of ovarian cancer and natural compound anticancer properties. His other honors and distinctions include a recent nomination for the West Virginia Professor of the Year Award, 2013 Faculty Member of the Year Award, featured professor in the 2013 spring issue of Neuron, as well as a postdoctoral fellowship from USDA and Oklahoma State University.

Chen received his undergraduate and graduate degrees from Zhejiang University in China. He later earned his second masters degree and a doctoral degree from Washington State University.

Alderson Broaddus (AB) University is a private, four-year institution of higher education located on a historic hilltop in Barbour County in Philippi, West Virginia. Since its founding in 1871, AB has been a leader and innovator in higher education, with accolades in the health and natural sciences.

MDPI is a platform for peer-reviewed, scientific open access journals which is operated by MDPI AG, based in Basel, Switzerland. MDPI publishes over 70 diverse electronic, open access journals. MDPI aims to have all of its journals covered by the Science Citation Index Expanded (SCIE) and Scopus. Several journals have already been covered by SCIE for several years and have received official impact factors.

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AB Professor named topic editor of journal | News, Sports, Jobs - The Inter-Mountain

Inflammation caused by radiation can promote survival of triple-negative breast cancer cells – News-Medical.net

While radiation is successfully used to treat breast cancer by killing cancer cells, inflammation caused as a side-effect of radiation can have a contrary effect by promoting the survival of triple-negative breast cancer cells, according to research published online in the International Journal of Radiation Biology by Jennifer Sims-Mourtada, Ph.D., director of Translational Breast Cancer Research at ChristianaCare's Helen F. Graham Cancer Center & Research Institute.

Accounting for 15-20% of all breast cancers, triple-negative breast cancer is faster growing than other types of breast cancers.

Dr. Sims-Mourtada's latest study, "Radiation induces an inflammatory response that results in STAT3-dependent changes in cellular plasticity and radioresistance of breast cancer stem-like cells," brings scientists closer to understanding the mechanisms behind this aggressive and hard-to-treat cancer. It shows that inflammation caused by radiation can trigger stem-cell-like characteristics in non-stem breast cancer cells.

"This is the good and the bad of radiation," Dr. Sims-Mourtada said. "We know radiation induced inflammation can help the immune system to kill tumor cells -- that's good -- but also it can protect cancer stem cells in some cases, and that's bad."

She added, "What's exciting about these findings is we're learning more and more that the environment the tumor is in - its microenvironment - is very important. Historically, research has focused on the genetic defects in the tumor cells. We're now also looking at the larger microenvironment and its contribution to cancer."

The term triple-negative breast cancer refers to the fact that the cancer cells don't have estrogen or progesterone receptors and also don't make too much of the protein called HER2. The cells test "negative" on all 3 tests. These cancers tend to be more common in women under age 40, who are African-American, Latina or who have a BRCA1 mutation.

My work focuses on cancer stem cells and their origination. They exist in many cancers, but they're particularly elusive in triple-negative breast cancer. Their abnormal growth capacity and survival mechanisms make them resistant to radiation and chemotherapy and help drive tumor growth."

Jennifer Sims-Mourtada, Ph.D., director of Translational Breast Cancer Research at ChristianaCare's Helen F. Graham Cancer Center & Research Institute

She and her team applied radiation to triple-negative breast cancer stem cells and to non-stem cells. In both cases, they found radiation induced an inflammatory response that activated the Il-6/Stat3 pathway, which plays a significant role in the growth and survival of cancer stem cells in triple-negative breast cancers. They also found that inhibiting STAT3 blocks the creation of cancer stem cells. Still unclear is the role IL-6/STAT3 plays in transforming a non-stem cell to a stem-cell.

For women living in Delaware, Dr. Sims-Mourtada's research is especially urgent: The rates of triple-negative breast cancer in the state are the highest nationwide.

At ChristianaCare, we are advancing cancer research to help people in our community today, while we also advance the fight against cancer nationwide. Dr. Sims-Mourtada's research is a dramatic step toward better treatments for triple-negative breast cancer."

Nicholas J. Petrelli, M.D., Bank of America endowed medical director of the Helen F. Graham Cancer Center & Research Institute

To advance her research on inflammation, last year Dr. Sims-Mourtada received a $659,538 grant from the Lisa Dean Moseley Foundation. The three-year grant will enable her and her team at the Cawley Center for Translational Cancer Research to continue investigating the role of cells immediately around a tumor in spurring the growth of triple-negative breast cancer and a possible therapy for this particularly difficult cancer.

"Our next step is to understand the inflammatory response and how we might inhibit it to keep new cancer stem cells from developing," Dr. Sims-Mourtada said.

Dr. Sims-Mourtada's research team previously identified an anti-inflammatory drug, currently used to treat rheumatoid arthritis, that has the potential to target and inhibit the growth of cancer stem cells and triple-negative breast cancer tumors. That research could set the stage for clinical investigation of the drug, alone or in combination with chemotherapy, to improve outcomes for patients with triple-negative breast cancer.

Source:

Journal reference:

Arnold, K.M., et al. (2020) Radiation induces an inflammatory response that results in STAT3-dependent changes in cellular plasticity and radioresistance of breast cancer stem-like cells. International Journal of Radiation Biology. doi.org/10.1080/09553002.2020.1705423.

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Inflammation caused by radiation can promote survival of triple-negative breast cancer cells - News-Medical.net

Here’s the Pro-Bernie Climate Scientist Op-Ed the Washington Post Wouldn’t Run – Gizmodo

On Sunday, the Washington Post published an opinion piece by Fred Hiatt, the opinion pages editor, entitled How Donald Trump and Bernie Sanders Both Reject the Reality of Climate Change. This false equivalence is, to put it bluntly, absolutely one of the most idiotic things I have ever seen.

Hiatts piece inexplicably attacks the climate plan Senator Bernie Sanders would implement as president (heres our analysis). While there are valid things to quibble with, Hiatt does a lot of hand waving bUt HoW wOuLd We PaY fOr It stuff and hand wringing over the idea that fossil fuel companies and the executives who run them should be prosecuted. He then turns to extensively quoting and paraphrase Patrick Pouyann, the chairman and CEO of Total, a [checks notes] large Paris-based oil giant currently being sued in France.

The whole post reads like an advertorial for Total (sample quote: Pouyann himself did not seem particularly hateful; on the contrary) and a carbon tax plan supported by the Climate Leadership Council, a group supported by Big Oil, including Total.

Both sidesing Trump and Sanders and credulously burbling out Big Oil talking points would be bad enough. But a group of scientists with the Sunrise Movement tweeted that the Post opinion section had previously rejected an op-ed they submitted defending Sanders climate plan and how seriously it takes the science. It was written in response to Joe Biden dismissing Sanders plan late last month, much as Hiatt did in his Sunday piece.

Earther reached out to Sunrise Scientists, and they shared their piece with us. Emails reviewed by Earther also confirm that a Washington Post editor explicitly declined to run the op-ed. Read the scientists article in full below, along with a list of authors who helped draft it.

Note: The letter is signed by the individual scientists and does not reflect the view of the institutions with which they are affiliated.

Joe Biden says Bernie Sanders Green New Deal is impossible.

We refuse that narrative. We are scientists here to refute Bidens claim that not a single, solitary scientist thinks that [Sanders Green New Deal would] work. Not only do we believe that it is possible for the U.S. to decarbonize electricity and transportation by 2030, we know that such a goal is imperative.

The Intergovernmental Panel on Climate Change, the worlds primary scientific authority on climate change, has been describing the immense harm that climate change will bring to the world and its peoples for decades. In 2018, it issued a report focused on the likely impacts of allowing global warming of 1.5. degrees Celsius (2.7 degrees Fahrenheit) above pre-industrial warming, concluding in its famously measured phrasing that the global impacts of such warming are going to be bad. One example: Any increase in global warming is projected to affect human health, with primarily negative consequences (high confidence). Nonetheless, limiting warming to 1.5 degrees Celsius can protect people and our planet from the most extreme anticipated consequences of climate change.

The planet has already warmed 0.8-1.2 degrees Celsius (1.4-2.2 degrees Fahrenheit), with an estimated future warming trajectory of 0.1-0.3 degrees Celsius (0.2-0.6 degrees Fahrenheit) per decade. Global mean sea level has already risen 89 inches (2124 centimeters) since 1880 and is expected to rise by another 10-30 inches (26 to 77 centimeters) by 2100 under a 1.5 degrees constraint, or more if we go past that. We are running out of time.

We know we must act. Constraining climate change in a way that is most protective of our planet, our families, and our homes requires cutting greenhouse gas emissions rapidly and permanently. We believe that Bernie Sanders Green New Deal proposal lays out a course of action that is matched to the scale of the challenge. It is possible. But we must commit wholeheartedly.

Sanders Green New Deal is informed by science, linking its targets and timelines to what the science tells us is critical for staving off the most devastating impacts of climate change. Just as importantly, it understands the challenge for what it is: A need to transform our economy to support a more sustainable, healthier future.

Accordingly, it addresses decarbonization systemically, focusing on where money needs to be spent, where social programs need to be implemented, and where people need support to do great things. The plan funds new, clean energy, leveraging successful New Deal models of public financing and control of power generation, and fully funds a just, five-year transition for workers in the fossil fuel industry.

The plan recognizes climate change as an emergency. It would make the U.S. a global leader on climate action, while ensuring funding for a just transition and industrialization of the developing world. And perhaps most importantly, the plan reflects that it is the American people who will make this happen. Thats why Sanders Green New Deal focuses on jobs, justice, and public ownership of the energy systems that we create and will be bolstered by other policy commitments like Medicare for All, student loan forgiveness, union empowerment, and other programs that recognize the power and dignity of all.

We know that it is possible to rise to the challenge of the climate crisis. And we know that Sanders Green New Deal is a commitment to people that recognizes that only together can we make this deeply ambitious and critically necessary plan work. As President John F. Kennedy said to Congress at the advent of the Space Race: I believe we possess all the resources and talents necessary. But the facts of the matter are that we have never made the national decisions or marshaled the national resources required for such leadership. We have never specified long-range goals on an urgent time schedule, or managed our resources and our time so as to insure their fulfillment.

It is again time to take urgent, visionary actions that rise to the challenge that we as scientists know is coming. It is time to commit to a Green New Deal.

Dr. Emily Grubert, Ph.D. in Environment and Resources from Stanford University

Dr. Eric Rehm, Senior Research Associate, UMI Takuvik/Arctic Remote Sensing at the Universit Laval

Dr. Dargan Frierson, Associate Professor of Atmospheric Sciences at University of Washington

Dr. Shannon Hateley, Ph.D. in Molecular and Cell Biology from the University of California, Berkeley

Dr. Peter Kalmus, Associate Project Scientist at the UCLA Joint Institute for Regional Earth System Science & Engineering

Matias Kaplan, PhD Candidate in Bioengineering at Stanford University

Isaac Larkin, PhD Candidate in Molecular Biology at Northwestern University

Yan Liu, BSc in Cell and Molecular Biology at San Francisco State University. Co-Founder and CEO, Biocaptivate

David Silverstone, PhD Candidate in Quantum Information Science at Yale University

Dr. Lucky Tran, PhD in Biology from Cambridge University

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Here's the Pro-Bernie Climate Scientist Op-Ed the Washington Post Wouldn't Run - Gizmodo

ReadCoor, Inc. Unveils True Spatial Sequencing Platform to Drive Groundbreaking Insights into Immuno-oncology, Neuroscience, and Infectious Disease -…

CAMBRIDGE, Mass.--(BUSINESS WIRE)--ReadCoor, Inc., a company leading true multi-omic spatial sequencing, today unveils its first product line, including multi-omic spatial sequencing assays and the RC2 instrument. The platform is powered by ReadCoors proprietary FISSEQ (Fluorescent in situ Sequencing) technology, which combines the massive multiplexity of next-generation sequencing (NGS) and high-resolution tissue imaging. The fully integrated platform is now available for use by researchers through ReadCoors Select Release Program (SRP), focusing on initial applications in immuno-oncology, neuroscience, and infectious disease, as well as a custom offering. ReadCoor has increased its Series B investment round to $30 million to accelerate commercial efforts.

The new platform simultaneously detects tens to thousands of RNA and DNA sequences, proteins, and therapeutic molecules at nanoscale 3D resolution in every cell within an intact tissue sample. The key products launched today are:

We firmly believe our true multi-omic sequencing technology will have a dramatic impact on medicine and healthcare, and this motivates us to provide researchers products that offer unprecedented and meaningful insights into human biology, said Richard Terry, Chief Executive Officer, Chief Technical Officer, and Founder of ReadCoor. Our Select Release Program serves as the foundation for researchers to develop new therapeutics and treatments to ultimately improve patient care.

Users within the SRP can use ReadCoors initial applications to support their specific research interests. The applications offer the following capabilities:

About ReadCoor, Inc.

ReadCoor is a technology company offering the first true spatial multi-omic platform to the global audience of researchers, clinicians, pharma and diagnostics companies to expand understanding of human biology and facilitate the creation of new therapeutics for patients. The companys RC2 platform simultaneously detects and reads the sequences of tens to thousands of RNA, DNA, proteins and therapeutics and visualizes sub-cellular nanoscale 3D resolution in every cell throughout any tissue section. The platform is based on ReadCoors proprietary Fluorescent in situ Sequencing (FISSEQ) technology, which combines the massive multiplexity of next generation sequencing (NGS) and high-resolution tissue imaging. Learn more at http://www.readcoor.com.

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ReadCoor, Inc. Unveils True Spatial Sequencing Platform to Drive Groundbreaking Insights into Immuno-oncology, Neuroscience, and Infectious Disease -...

Neuroscience Suggests that Virtues are the Basis of Wisdom, Says Dr Howard Rankin – PRNewswire

HILTON HEAD ISLAND, S.C., Feb. 24, 2020 /PRNewswire/ -- On the eve ofLent there is growing scientific evidence that virtues are the basis of wisdom. In his recent book, I Think Therefore I Am Wrong: A Guide to Bias, Political Correctness, Fake News and the Future of Mankind, Dr Howard Rankin shines light on the human thought process and shows it often to be seriously flawed. Referencing dozens of cognitive biases, binary thinking and absurd simplicity, Rankin not only describes the process but the reasons uncritical thinking is rampantand how itaffects many areas of the culture like education and healthcare.

A culture of reality-show emotionalism and egocentrism has contributed to the abandonment of critical thinking as have educational practices. Emotion almost always rules the narrative so the key to more objectivity is emotional awareness and control, writes Rankin.

"Wisdom is the recognition of complexity and the limits of knowledge," says Rankin.

How do you teach people to not just be more aware of these fundamental limitations of the human mind but also improve their thought processes?

"All the wise people of the past have suggested that virtue is the basis of wisdom. Now we are beginning to understand why," says Rankin.

Research over the recent past has shown a reciprocal relationship between wisdom and virtues, often perceived as greater self-awareness and a retreat from egotism. Research of those practicing virtues, like compassion and forgiveness, often shows an increase in the prefrontal cortex, the area of the brain responsible for planning and emotional regulation, and a reduction in the areas of the brain associated with emotion, like the amygdala.

"There's no question that the virtues, like humility, compassion and forgiveness involve emotional regulation and a reduction in egotism, which is exactly what is required of wisdom," says Rankin whose book outlines 20 core virtues and ways to engage in them.

"Being smart is not the same as being wise. Knowing facts is one thing, but awareness of the limitations of thinking is quite another. In that sense altruism is more important than algebra, compassion more important than chemistry and humility more important than history," says Rankin.

Referencing the future of mankind, Rankin expresses concerns that the continued drive towards egotism and the abandonment of critical thinking will lead to disaster. He cites research into the collapse of societies which shows that cognitive bias, egotism, and environmental change, have often been a prelude to disastrous collapse.

As Rankin writes in his book Power Talk: The Art of Effective Communication, "People aren't logical, they're psychological, often with the emphasis on the psycho."

Now, there is confirmation that by doing good, we can help ourselves as well as others.

Dr. Rankin's book can be found here. bit.ly/2lSHU7U

Dr. Rankin also hosts the How Not To Think podcasthttps://www.buzzsprout.com/730841

Contact: Howard RankinEmail: 234230@email4pr.com Ph: 843.247.2980 http://www.IthinkthereforeIamwrong.com

SOURCE Dr Howard Rankin

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Neuroscience Suggests that Virtues are the Basis of Wisdom, Says Dr Howard Rankin - PRNewswire

Three Reasons Why Most Healthy Food May Not Improve Your Productivity, and What Actually Will – Thrive Global

If you have some level of interest in health consciousness, youve probably read You are what you eat! somewhere more than once in your life.

And while theres definitely some truth to these sayings, we seem to have abandoned some of the key components of neuroscience that illustrate our bodies innate ability to perform, increase mental acuity, and focus under the right conditions, independent of the food we choose to consume.

Thats not to say that I recommend inhaling a large pepperoni pizza and three pints of chunky ice cream tonight (well, maybe just one pint). Food is important, and its associations with our productivity and well-being can be significant but when your body is experiencing incoherence from negative emotions or thought patterns, the benefits of nutrition become marginal.

Most people spend 70% of their time stuck in the emotional hormones of stress. The problem is that these hormones trigger the immune system to shut down and push blood from our core to our extremities.

In other words, we move from a state of homeostasis to fight-or-flight. And although the fight-or-flight response is excellent if you are being chased by a T-rex, it is incredibly damaging to stay in that state for long periods of time.

So if you are drinking green juice and taking vitamin shots, but spend the rest of your day stressing about your exs new partner, the likelihood of absorbing nutrients decreases by up to 80%.

Regardless of any potential association between food and productivity, your body is significantly less capable of utilizing these advantages under the hormones of stress.

How you think, feel, and act on a daily basis is based on 95% subconscious neurological programs. More specifically, the vast majority of your behaviors are on autopilot and you arent aware of them.

When youre programmed into low-level emotions like stress, fear, depression, unworthiness, and so on, youre likely to inhabit behaviors that correspond to those emotions; like self-sabotage, procrastination, and erratic or poor decision making.

And yet, you may continue to eat salads with avocado diligently for lunch every day. But if your programmed thoughts and behaviors breed a lack of focus, your lunchtime salads likely wont make a dent in your productivity.

Some of the latest research in neuroscience shows that having incoherence between the heart and brain due to negative emotions compromises your focus, and has a direct negative effect on your digestive system.

Incoherence is when your body sends disordered signals between the heart and brain, like an angry child scribbling on a piece of paper.

For example, if youre in the shower and you start thinking about the driver that cut you off and flipped you the bird, youre probably having an incoherent signal between your heart and brain.

And since these negative emotions can impair your digestive system too, eating healthy food isnt going to help your mental focus anyway.

So if youre about to go to your cranky mother-in-laws house for dinner, you might want to fantasize about winning a lottery ticket before reaching for the steamed broccoli.

Whether its derived from the hormones of stress, your neurological program, or incoherence between the heart and brain, its clear that negative emotions tamper your brain and body and prevent productivity, independent of nutrition.

So now what?

Well, Im going to show you the number one strategy that helps combat these barriers so that you can not only get the most from your nutrition, but also use neurological rewiring to double your results.

Ready for it?

its called meditation.

I know, its a little disappointing. You thought it would be a cool new technology, a supplement, or something more sophisticated right?

Thats the point: most of us are looking for something outside of us to solve an underlying issue inside of us.

I meet many over-achievers who believe that meditation just isnt for them or that somehow its for someone with a certain set of characteristics different from their own.

But the truth is, meditation is one of the top ways to get beyond yourself, rewire your negative programs, and substantially reduce or eliminate stress.

So if youre stuck in a pattern of unproductivity and the green juice doesnt seem to be doing you any good, I challenge you to give meditation a go what do you have to lose?

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Three Reasons Why Most Healthy Food May Not Improve Your Productivity, and What Actually Will - Thrive Global

Award-winning Sheffield neuroscientists honoured at Buckingham Palace reception – University of Sheffield News

21 February 2020

Neuroscience research at the University of Sheffield has been recognised for the real benefits it is delivering to the public in a ceremony at Buckingham Palace (Thursday 20 February 2020).

The University was presented with the Queens Anniversary Prize (QAP) medal and scroll by TRH The Prince of Wales and The Duchess of Cornwall on behalf of Her Majesty The Queen.

The prize is the fifth awarded to the University of Sheffield, and recognises the work that the Sheffield Institute for Translational Neuroscience (SITraN) at the University does to improve patient outcomes for people living with some of the most devastating neurodegenerative diseases.

Achievements highlighted by the award included:

Professor Dame Pamela Shaw, Director of SITraN and the NIHR Sheffield Biomedical Research Centre, said: This prize recognises the University of Sheffield as a centre for excellence in neuroscience research and teaching, where our researchers are making life-changing discoveries and progress in treating some of the most devastating neurological diseases, making a real difference to patients lives.

As well as making life-changing discoveries today, we are also nurturing the next generation of talented neuroscience students, whose research will lead to pioneering treatments for those living with neurological diseases in the future.

We hope this award will help inspire confidence in patients and their families, research partners and donors, as we continue to make discoveries that deepen the understanding of neurological diseases and open up the potential for new treatments and therapies.

SITraNs vision is to harness the rapidly emerging, exciting developments in neuroscience to translate into new treatments and improved quality of life for patients with neurodegenerative disorders such as Parkinsons Disease, MND, Alzheimers Disease, MS and Dementia.

The centre - considered a world-leader in neuroscience research - will celebrate its 10th anniversary this year. Its work forms part of the University of Sheffields Neuroscience Institute, which aims to bring academics together from across medicine, science and engineering to translate scientific discoveries from the lab into pioneering new treatments.

Sir Damon Buffini, Chairman of the Royal Anniversary Trust, said: It has been fantastic to celebrate the 13th Round of Prize-winners at Buckingham Palace alongside TRH Prince of Wales and the Duchess of Cornwall. The Royal Anniversary Trust showcased the exceptional, innovative and impactful work of our colleges and universities throughout the UK. We look forward to seeing how the work develops and progresses over the coming years!

The University of Sheffield

With almost 29,000 of the brightest students from over 140 countries, learning alongside over 1,200 of the best academics from across the globe, the University of Sheffield is one of the worlds leading universities.

A member of the UKs prestigious Russell Group of leading research-led institutions, Sheffield offers world-class teaching and research excellence across a wide range of disciplines.

Unified by the power of discovery and understanding, staff and students at the university are committed to finding new ways to transform the world we live in.

Sheffield is the only university to feature in The Sunday Times 100 Best Not-For-Profit Organisations to Work For 2018 and for the last eight years has been ranked in the top five UK universities for Student Satisfaction by Times Higher Education.

Sheffield has six Nobel Prize winners among former staff and students and its alumni go on to hold positions of great responsibility and influence all over the world, making significant contributions in their chosen fields.

Global research partners and clients include Boeing, Rolls-Royce, Unilever, AstraZeneca, Glaxo SmithKline, Siemens and Airbus, as well as many UK and overseas government agencies and charitable foundations.

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Award-winning Sheffield neuroscientists honoured at Buckingham Palace reception - University of Sheffield News

Canadian actor Hamza Haq on yearning for roles rooted in reality – The Globe and Mail

Canadian actor Hamza Haq seen in CTV's medical drama Transplant.

Fabrice Gaetan

From an extra who blends into the background to the lead character in the new CTV medical drama Transplant, Hamza Haq has slowly and steadily worked his way up in an industry known for its fickleness. There were tough moments in between, especially when he decided not to play characters simply labelled as terrorist, turning down gigs that came with substantial paycheques.

As an actor, hes most interested in storytelling that goes beyond the facade, where fiction is based on a dose of reality. In Transplant, Haq plays Bashir Bash Hamed, a Syrian doctor with experience working in a war zone, now trying to make a new life for himself and his young sister in Canada. Although he starts off as an immigrant working in a Lebanese restaurant, circumstances soon see him get a residency in the ER at Torontos fictional York Memorial Hospital.

In some ways, the story mirrors Haqs own family history. His parents an engineer father and organic chemist mother moved from Pakistan to Canada via Saudi Arabia to provide a better future for their kids, and still work in jobs that dont account for their educational training.

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The Globe and Mail caught up with Haq, 29, on the phone, shortly before he stepped onto the red carpet at the 70th Berlinale (Berlin International Film Festival) for the opening night film, My Salinger Year. Directed by Canadian filmmaker Philippe Falardeau, the film stars Margaret Qualley and Sigourney Weaver, as well as Haq.

How is Berlin treating you?

Its cool. The hotel is great. I came in yesterday on an overnight flight, and I couldnt sleep. My childhood buddy from Ottawa happens to be in Amsterdam. He just met me here, we ordered room service and fell asleep by 7:30 p.m. So, really livin it up!

I was reading an article about you, and it said that as the youngest of four siblings, you were often the entertainer for the family. How so?

My role in the family has been comic relief for a very long time. At family weddings or anything like that, when everyone else was a little shy, it would be like, Hamza, get up and dance. And I always enjoyed that. We grew up on Bollywood, mimicking that choreography. For a cousins wedding, I memorized a whole dance routine. That was my first gig. I was seven.

Then you ended up studying neuroscience at Carleton University before switching to accounting. You graduated with a degree in film studies and law. Why neuroscience to start?

You know doctor, lawyer, engineer. To become one of those things, sure, was expected. But I just needed context. I wanted to understand degenerative brain disease more. As first-generation immigrants, our parents are living longer than their parents, but as a result they are having to deal with things people in their family never had to deal with like dementia and Alzheimers. And I thought neuroscience gave the correct context to me as to why I would spend my life studying this thing. But I ended up taking up acting to study for life instead.

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Now that youve ended up playing a doctor on a TV series, how did your family react?

Everybody made that joke. It was inevitable, really. Youre a brown actor. Youre going to play a doctor eventually. It was cool to do it in this capacity, with the narrative that we have.

Another role that brown actors often end up auditioning for is that of a terrorist. After a while you decided to turn down those roles. Why?

Terrorism in the Muslim world does exist, but the way its portrayed, theres no truth behind the character. If I were approached to do somebody who was being radicalized, or had any more context than, Oh yeah, hes Muslim if I were given an opportunity to tell that story of how one becomes that way, and the dangers of things that lead people that way, Id be happy to tell that story.

I had played Arab bad guys, and I was tired of getting the note that, Yeah, but a little bit more angry, a little bit more Arab. You know, more Arab!

For the role of Bash, or Dr. Bashir Hamed, you had to learn Arabic, speak in a dialect. Tell me about rounding out this character.

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[Transplants creator and writer] Joseph Kay and I have done this before for another role, trusting the information that I bring to the table, and also doing an insane amount of research. We had so many great consultants on the show, from Syrian refugees to doctors.

I even had a personal trainer, and he turned out to be a Syrian refugee. I love that, I love being involved and bringing forth characters that are based on truth. Before we add a layer of fiction, if there isnt a foundation of truth, theres no point in telling the story. I only hope I am fortunate enough to find other roles that allow me the same process.

How else did you prepare for this role?

We had many great medical consultants, like Dr. Zachary Levine at Montreal General. We went to boot camp to learn how to hold instruments properly, how best to look competent. I thought it was a lot of fun. Ive always had an aptitude for science, and a base level interest. It was really cool for me to have that hands-on experience. And to see a life that could have been! And who knows, could still be.

You started off as an extra, and now youre the lead actor in a medical drama. Do you feel like youve made it?

Ill give myself some credit, for working hard, and not listening to those uncles and aunties who said, Maybe you should get a real job. But Ill give most of the credit to my immigrant parents, who came to Canada to provide opportunities to their kids that they never had.

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Transplant debuts on CTV on Feb. 26, at 9 p.m. EST.

This interview has been edited and condensed for clarity.

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Canadian actor Hamza Haq on yearning for roles rooted in reality - The Globe and Mail