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$10 million gift accelerates research to improve cancer therapies, extend benefits to more patients – Newswise

Newswise Researchers at the University of Chicago Medicine will come together to develop personalized therapies for hard-to-treat cancers, thanks to a $10 million gift from the Jonas family.

The gift establishes the David and Etta Jonas Center for Cellular Therapy at UChicago Medicine, named for David Jonas and his late wife, Etta.

The center unites a team of experts dedicated to improving cellular therapy, especially T-cell treatments like CAR (chimeric antigen receptor) T-cell therapy, an emerging form of cancer treatment. CAR T-cell therapy works by supercharging patients white blood cells to seek out and destroy cancer cells. Although this therapy has, in some cases, led to complete remission, it is not always successful and is currently limited to treating certain blood cancers.

Through the David and Etta Jonas Center for Cellular Therapy, researchers at UChicago Medicine will work to overcome these challenges and realize the full potential of cellular therapy. This includes efforts to improve the therapys overall effectiveness and extend its benefits to a much broader group of patients, including those with cancers that are currently difficult to treat.

I was impressed by UChicago Medicines multidisciplinary research program and commitment to attaining tangible outcomes that will really serve cancer patients, Jonas said. They have all the key elements for a successful research program: experience in clinical trials, access to the most leading-edge technology, a tremendous track record in attracting scientific talent, and a strong team to lead the program.

Developing truly personalized therapies T-cells patrol our bodies, searching for signs of infection and disease. When T-cells detect an abnormal protein on the surface of a cell, called an antigen, they latch onto it with a matching receptor. Like puzzle pieces, the antigen and T-cell receptor bind together, triggering an immune response that destroys the cell.

Some cancers, however, develop ways to trick the immune system, such as by disguising themselves as healthy cells or by shutting down the immune response altogether. CAR-T cell therapy helps to resolve this by modifying patients T-cells in the lab, so they can better recognize and target cancer-specific antigens.

However, there isnt a one-size-fits-all approach to targeting antigens since they are unique to each patient and his or her tumor; nor is there a reliable method for predicting which antigens a given tumor will express. To address these challenges, Hans Schreiber, MD, PhD, professor of pathology at the University of Chicago, has developed a new method for personalized T-cell therapy. By characterizing a patients T-cell receptors, he is able to engineer a customized therapy that accurately targets the tumors unique antigens.

This highly personalized approach to T-cell therapy can safely target cancer cells, without damaging healthy tissue. It also has the potential to treat other cancer typesbeyond blood cancersincluding hard-to-treat solid tumors, like pancreatic and ovarian cancers. With new investments in infrastructure and expertise, the Jonas Center will accelerate this research effort and develop this therapy for clinical trials for patients with metastatic solid tumors, through a collaboration with Michael Bishop, MD, professor of medicine and director of the Cellular Therapy Program, and Amittha Wickrema, PhD, professor of medicine.

This gift will allow us to translate these groundbreaking discoveries made in the laboratory into novel cancer therapies, which have the potential to treat not just blood cancers, but also solid tumors, said Kenneth Polonsky, MD, dean and executive vice president for medical affairs at the University of Chicago. If we can accomplish even part of that, it will be a major transformation in cancer therapy that will change the lives of many patients here in the United States and around the world.

Improving response ratesWhile some patients have an excellent response to CAR T-cell therapy, others do not respond or relapse shortly after undergoing treatment.

Bishop is leading an effort to identify factors that contribute to the therapys success, which is showing response rates greater than 90% for patients with acute lymphoblastic leukemia (ALL).

Bishop suspects that the fitness of patients T cells may determine if, and how well, they respond to therapy. Like a soccer team, it is important that patients T cells are not only fit enough to successfully take on their opponent (the cancer), but they must also be able to sustain their energy long enough to defeat their opponent and win the game.

By identifying the qualities that make T cells fit, Bishop and his colleagues seek to predict how a patient will respond to the therapy in advance. This way, a patients T cells could be sequenced prior to undergoing treatmentallowing physicians to gauge if their immune system will be able to wage a successful attack against the cancer. In cases where the patients T cells are deemed unfit, the researchers aim to develop interventions to improve their fitness.

This is the most exciting time in my entire career, Bishop said. We finally have hope for patients who previously didnt have hope. And now we are working to improve upon these results. Within the next 10 years, I think these treatments are going to become more effective, less toxic, and most importantly, will give new options to a broader scope of patients.

Building an infrastructure for success The Jonas familys gift will provide essential funding to advance research initiatives, while also putting in place the necessary infrastructure to sustain a successful research enterprise in the years to come. To this end, the Jonas Center will allow for: Recruitment of leading experts in T-cell biology and cell engineering Expansion of research and clinical trials infrastructure Acquisition of specialized technology and equipment necessary to translate discoveries made in the laboratory to the clinic An annual lecture that brings together leaders in cellular therapy and fosters dissemination of the latest innovations in the field

We feel extremely proud and appreciative to have the opportunity to partner with the University of Chicago in this effort, Jonas said. We see our contribution as the seed for building a robust program that will lead to the next breakthrough in cancer therapy.

This gift represents the single largest donation to UChicago Medicine for cellular therapy research.###

About David Jonas David Jonas is the founder, president and CEO of JVC Investment Partners. He is also the founder, former chairman and CEO of PharMEDium Healthcare Corporation. Prior to founding PharMEDium, David was a co-founder and chief operating officer of Renal Therapy Services Worldwide Inc.

About the University of Chicago Medicine & Biological SciencesThe University of Chicago Medicine, with a history dating back to 1927, is one of the nations leading academic health systems. It unites the missions of the University of Chicago Medical Center, Pritzker School of Medicine and the Biological Sciences Division. Together with Harvey-based Ingalls Memorial, UChicago Medicine has 1,286 licensed beds, nearly 1,300 attending physicians, about 3,200 nurses and over 1,100 residents and fellows.

Visit UChicago Medicines health and science news blog at http://www.uchicagomedicine.org/forefront.Twitter @UChicagoMedFacebook.com/UChicagoMed

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$10 million gift accelerates research to improve cancer therapies, extend benefits to more patients - Newswise

What’s This Is of Organism in Biology? – 47abc – WMDT

You will find various scientists using the languagelifetimeculture to mean the same thing.

These technological definitions of existence have been known for centuries and it has never been possible to obtain another definition of lifestyle to better suit them. These arent significant enough to impact the significance of those words, although Ofcourse there are gaps among kinds and living organisms. The wordaliveliving things have been utilized to spell out an assortment of household objects along with unique sorts of non-living organisms as well https://expert-writers.net/thesis-help as course its really just a generalization.

These definitions of life have found software even fiction. As an instance, exactly how frequently have you ever heard that the termcell and have wondered exactly what this supposed? A mobile can be a basic unit in life, plus it is a superior notion to specify just what a cell is in terms of life. It does not have to be cells surviving cells, as cells are divided into the two categories of animal and fungus tissues.

The expression organism is also a significant element in mathematics because it relates to various kinds of living programs in a particular environment. Nevertheless, the organism significance is employed for just about any type of system which lives in a given atmosphere. Because theyve similar intentions from mathematics the organism meaning is used at the same manner since the concept of the cell.

The organism meaning in chemistry describes a lodestar.asu.edu set of living organisms which can be categorized based on similarities or similarities or which may be exceptional. It indicates some thing which can be categorized based on a unit or cells presence . Only because they reproduce without limitation, but minus a definition these tissues are rather vital in character. These cells then replacingthemselves over again and then replicate by splitting as well as in a few scenarios it is possible to divide a single cell.

When it has to do with cells, then they could divide by dispersing out or by enlarging in size and spreading out on a perpendicular axis or enlarging horizontally. These mechanisms are determined by the surroundings. Although other organisms do not have some function for mobile division, some creatures utilize the mobile division to reproduce.

The receptor significance in mathematics is significant as it supplies a foundation for contrast and comparison. expert essay writers It will make it possible to think about the distinctions in between also the similarities, their own variances, and organisms that may be seen between these organisms. Sir Francis Galton, that was the very first to ever use the term in his book Animal Magnetism discovered and defined the organism meaning in biology.

The receptor significance in research has been employed to explain a variety of phenomena, by the development of people even and to the gaps between both plants and animals between human beings and other organisms. This is of an organism used in mathematics may be overall as you are able to see plus it may likewise be specific. At an identical time it may be equally special and general in certain scenarios.

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What's This Is of Organism in Biology? - 47abc - WMDT

More than 70 percent of coronavirus cases in Israel came from US: study | TheHill – The Hill

More than 70 percent of coronavirus cases in Israel came from the U.S., according to a study released Monday by Tel Aviv University.

Researchers mapped the spread of the virus by decoding genomic sequences of virus strains in determining thatthe majority of Israels cases originated in the U.S., Adi Stern of the School of Molecular Cell Biology and Biotechnology at the university told The Jerusalem Post.

The researchersused about 4,700 sequences taken globally to compare local patient sequences.

The study, published on medRxiv.org, found the remaining infections in Israel came from Europe and elsewhere, including 8 percent from Belgium, 6 percent from France, 5 percent from England and 3 percent from Spain. The researchers concluded that all infections came from abroad.

Israel did not shut down travel from the U.S. and most visitors from abroad until March 9, while flights from Europe and other areas of the world shut down between Feb. 26 and March 4.

There was this gap in policy, and this gap allowed people to return from the US who thought that they could go wherever they wanted, so they probably spread the virus that way, Stern told the Post.

Some infections originating from Europe and Southeast Asia also entered the country, but those patients were quarantined early, limiting the coronaviruss spread, the Post reported.

The researchers determined that between 1 percent and 10 percent of patients spread about 80 percent of cases at super-spreading events, such as large parties or other social gatherings. But the study determined that social distancing efforts did reduce the amount of spread.

Before the study, health officials depended on patient feedback in order to track the spread.

Tel Aviv University was assisted by 11 other health institutes or universities, including Emory University, in the study.

Israel has confirmed 16,643 cases in the country, leading to at least 276 deaths, according to data from Johns Hopkins University.

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More than 70 percent of coronavirus cases in Israel came from US: study | TheHill - The Hill

Research Associate at the Chair of Applied Zoology job with TECHNISCHE UNIVERSITAT DRESDEN (TU DRESDEN) | 207131 – Times Higher Education (THE)

At TU Dresden, Faculty of Biology, Institute of Zoology, the Chair of Applied Zoology offers a project position as

Research Associate

(Subject to personal qualification employees are remunerated according to salary group E 13 TV-L)

starting 01.08.2020, until 31.12.2021. The period of employment is governed by 2 (2) Fixed Term Research Contracts Act (Wissenschaftszeitvertragsgesetz-WissZeitVG). The position offers the chance to obtain further qualification. Balancing family and career is an important issue. The post is basically suitable for candidates seeking part-time employment.

Tasks: In a BMWi-funded national cooperation project, you shall investigate expression profiles of a carp cell line and quantify the expression of specific signaling network components (e.g. endocrine disruption). You shall identify regulatory sequences of suited candidate genes and test their functionality in reporter assays. Such in vitro data shall be compared with in vivo data of other fish species. The signal networks shall be compared to data of mammals with respect to ecotoxicological relevance. The project covers a wide range of techniques of molecular and cellular biology and include NGS transcriptomics, in silico analysis, cloning and qPCR. We offer state of the art facilities and expect your participation in presentation and publication of the results.

Requirements: university degree in biology or a closely related field. We are seeking for a highly motivated scientist with knowledge of molecular biology, cell biology and microscopic techniques. Experience in bioinformatics and the analysis of RNAseq data are highly desirable. An independent working style and the handling of animals is expected. The national cooperation project requires team spirit and solid knowledge of the German or the English language.

Applications from women are particularly welcome. The same applies to people with disabilities.

Please send your application documents using code number 235 in the subject header until 09.06.2020 (stamped arrival date of the university central mail service applies) to: TU Dresden, Fakultt Biologie, Institut fr Zoologie, Professur fr Angewandte Zoologie, Herrn Dr. Alexander Froschauer, Helmholtzstr. 10, 01069 Dresden or via the TU Dresden SecureMail Portal https://securemail.tu-dresden.de by sending it as a single pdf document to alexander.froschauer@tu-dresden.de. Please submit copies only, as your application will not be returned to you. Expenses incurred in attending interviews cannot be reimbursed.

Reference to data protection: Your data protection rights, the purpose for which your data will be processed, as well as further information about data protection is available to you on the website: https://tu-dresden.de/karriere/datenschutzhinweis

Please find the german version under:

https://tu-dresden.de/stellenausschreibung/7670

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Research Associate at the Chair of Applied Zoology job with TECHNISCHE UNIVERSITAT DRESDEN (TU DRESDEN) | 207131 - Times Higher Education (THE)

New Stem Cell-Based Topical Solution Helps Bald People Regrow Hair – SciTechDaily

A clinical trial showed the ability of a stem cell-based topical solution to regrow hair in people with male/female pattern baldness.

The results of a clinical trial released today (May 18, 2020) in STEM CELLS Translational Medicinedemonstrate how a topical solution made up of stem cells leads to the regrowth of hair for people with a common type of baldness.

Androgenetic alopecia (AGA) commonly known as male-pattern baldness (female-pattern baldness in women) is a condition caused by genetic, hormonal and environmental factors. It affects an estimated 50 percent of all men and almost as many women older than 50. While it is not a life-threatening condition, AGA can lower a persons self-esteem and psychological well-being. There are a few FDA-approved medications to treat hair loss, but the most effective can have side effects such as loss of libido and erectile dysfunction. Therefore, the search continues for a safer, effective treatment.

Adipose tissue-derived stem cells (ADSCs) secrete several growth hormones that help cells develop and proliferate. According to laboratory and experimental studies, growth factors such as hepatocyte growth factor (HGF), vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF) and platelet-derived growth factor (PDGF) increase the size of the hair follicle during hair development.

A more enriched adipose-derived stem cells-constituent extract (ADSC-CE) with stem cell proteins is obtained by disruption of the ADSC membrane using a low frequency of ultrasound wave. Credit: AlphaMed Press

Recent studies have shown that ADSCs promote hair growth in both men and women with alopecia. However, no randomized, placebo-controlled trial in humans has explored the effects and safety of adipose-derived stem cell constituent extract (ADSC-CE) in AGA. We aimed to assess the efficacy and tolerability of ADSC-CE in middle-aged patients with AGA in our study, hypothesizing that it is an effective and safe treatment agent, said Sang Yeoup Lee, M.D., Ph.D., of the Family Medicine Clinic and Research Institute of Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital in South Korea. He led the group of researchers, which also included colleagues from Pusan National University School of Medicine, Pusan National University Yangsan Hospital and T-Stem Co., Ltd.

The team recruited 38 patients (29 men and nine women) with AGA and assigned half to an intervention group that received the ADSC-CE topical solution and half as a control group that received a placebo. Twice daily, each patient applied the ADSC-CE topical solution or placebo to their scalp using their fingers.

At the end of 16 weeks, the group that received the ADSC-CEs had a significant increase in both hair count and follicle diameter, reported the studys senior author, Young Jin Tak, M.D., Ph.D.

Dr. Lee added, Our findings suggest that the application of the ADSC-CE topical solution has enormous potential as an alternative therapeutic strategy for hair regrowth in patients with AGA, by increasing both hair density and thickness while maintaining adequate treatment safety. The next step should be to conduct similar studies with large and diverse populations in order to confirm the beneficial effects of ADSC-CE on hair growth and elucidate the mechanisms responsible for the action of ADSC-CE in humans.

For the millions of people who suffer from male-pattern baldness, this small clinical trial offers hope of a future treatment for hair regrowth, said Anthony Atala, M.D., Editor-in-Chief ofSTEM CELLS Translational Medicineand director of the Wake Forest Institute for Regenerative Medicine. The topical solution created from proteins secreted by stem cells found in fat tissue proves to be both safe and effective. We look forward to further findings that support this work.

###

Reference: A Randomized, Double-blind, Vehicle-Controlled Clinical Study of Hair Regeneration Using Adipose-Derived Stem Cell Constituent Extract in Androgenetic Alopecia 18 May 2020, STEM CELLS Translational Medicine.DOI: 10.1002/sctm.19-0410

AboutSTEM CELLS Translational Medicine:STEM CELLS Translational Medicine(SCTM), co-published by AlphaMed Press and Wiley, is a monthly peer-reviewed publication dedicated to significantly advancing the clinical utilization of stem cell molecular and cellular biology. By bridging stem cell research and clinical trials, SCTM will help move applications of these critical investigations closer to accepted best practices. SCTM is the official journal partner of Regenerative Medicine Foundation.

About AlphaMed Press: Established in 1983, AlphaMed Press with offices in Durham, NC, San Francisco, CA, and Belfast, Northern Ireland, publishes two other internationally renowned peer-reviewed journals:STEM CELLS, celebrating its 38th year, is the worlds first journal devoted to this fast paced field of research.The Oncologist, also a monthly peer-reviewed publication, entering its 25th year, is devoted to community and hospital-based oncologists and physicians entrusted with cancer patient care. All three journals are premier periodicals with globally recognized editorial boards dedicated to advancing knowledge and education in their focused disciplines.

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New Stem Cell-Based Topical Solution Helps Bald People Regrow Hair - SciTechDaily

COVID-19 Impact on Human Embryonic Stem Cell Market 2020 Regional Outlook, Latest Trend, Share Analysis, Growth, Application and Forecast to 2027 -…

The Covid-19 (coronavirus) pandemic is impacting society and the overall economy across the world. The impact of this pandemic is growing day by day as well as affecting the supply chain. The COVID-19 crisis is creating uncertainty in the stock market, massive slowing of supply chain, falling business confidence, and increasing panic among the customer segments. The overall effect of the pandemic is impacting the production process of several industries including Life science Industry, and many more. Trade barriers are further restraining the demand- supply outlook. As government of different regions have already announced total lockdown and temporarily shutdown of industries, the overall production process being adversely affected; thus, hinder the overall Human Embryonic Stem Cell market globally. This report on Human Embryonic Stem Cell market provides the analysis on impact on Covid-19 on various business segments and country markets. The report also showcase market trends and forecast to 2027, factoring the impact of Covid -19 Situation.

The human embryonic stem cells are obtained from the undifferentiated inner mass cell of the human embryo and human fetal tissue. The human embryonic stem cell can replicate indefinitely and produce non-regenerative tissue such as myocardial and neural cells. This potential of human embryonic stem cell allows them to provide an unlimited amount of tissue for transplantation therapies to treat a wide range of degenerative diseases. Hence, human embryonic stem cells are used in the treatment of various diseases such as Alzheimers disease, cancer, blood and genetic disorders related to the immune system and others.

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MARKET DYNAMICSThe global human embryonic stem cell market is expected to grow in upcoming years, factors driving the growth of market are rise in incidences of neurological disorders, increase in investment by government and other organization for research activities, awareness among people about stem cell therapeutic potency for disease treatment. On the other hand emerging stem cell banking services is expected to offer lucrative opportunities in growth of human embryonic stem cell market.

The report also includes the profiles of key human embryonic stem cell market companies along with their SWOT analysis and market strategies. In addition, the report focuses on leading industry players with information such as company profiles, components and services offered, financial information of last 3 years, key development in past five years.

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Market size & shares

Market trends and dynamics

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Competitive landscape

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Market segmentation:

Human Embryonic Stem Cell Market to 2027 Global Analysis and Forecasts By Product Type (Totipotent Stem Cell, Pluripotent Stem Cell, Unipotent stem Cell); Application (Regenerative Medicine, Stem Cell Biology Research, Tissue Engineering, Toxicology Testing); End User (Therapeutics Companies, Cell & Tissue Banks, Tools & Reagents Companies, Others) and Geography

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COVID-19 Impact on Human Embryonic Stem Cell Market 2020 Regional Outlook, Latest Trend, Share Analysis, Growth, Application and Forecast to 2027 -...

Students – Complete Anatomy

Complete Anatomy features in Apple Launch Learn more

Master structures in 3D to prepare for labs with the Student Plus license.

Complete Anatomy Courses have allowed me to clearly understand the functions that each structure has.

Aurora PalamaraMed student, Italy

Parts, surfaces & landmarks

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Students - Complete Anatomy

Anatomy definition and meaning | Collins English Dictionary

nounWord forms: plural -mies1.the science dealing with the structure of animals and plants2.

the structure of an animal or plant, or of any of its parts

dissection of all or part of an animal or plant in order to study its structure

the human body

Most material 2005, 1997, 1991 by Penguin Random House LLC. Modified entries 2019by Penguin Random House LLC and HarperCollins Publishers Ltd

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Anatomy definition and meaning | Collins English Dictionary

Anatomical Models | 3B Smart Anatomy with Free Anatomy App …

NEW: 3B Smart Anatomy a new generation of anatomical models. 3B SMART ANATOMY is designed to close the gap between analog and digital learning.a giant step in Anatomy Education and exclusive to all original 3B Scientific anatomical models. Virtual meets Reality the concept of 3B SMART ANATOMY 3B Scientific has teamed up with 3D4Medical, the world-leader in the development of ...

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Anatomical Models | 3B Smart Anatomy with Free Anatomy App ...

Its Anatomy Keeps Changing But What Will it Take for War to End? – The Wire

Earlier this week, an attack that claimed 24 lives including of two babies at a maternity hospital in Afghanistan left many in shock. Although the three attackers were later killed by security forces, a bigger storm was brewing in the countrys political climate. Afghanistan President Ashraf Ghani ordered the armed forces to switch to offensive mode against the Taliban, and the Taliban responded by dubbing it declaration of war.

According to the Afghan National Security Council, the Taliban has conducted an average of 55 attacks per day since the US-Taliban peace deal in late February. The Taliban in turn has accused the US of carrying out 33 drone-strikes and airstrikes in March, violating the terms of the deal.

Afghanistan is seemingly moving towards peace but it seems to be only on paper. This seems ironical considering political pundits around the world have repeatedly argued that war is fast becoming redundant. So how then do we make sense of the recent attacks in Afghanistan and other conflict centres in the world?

History has some answers.

In 261 BC, Emperor Ashoka of the Maurya dynasty, which ruled the Indian subcontinent, attacked Kalinga in the east in one of the bloodiest battles in South Asian history, killing more than 1.5 lakh people per official records. But after he won, the scale of destruction dawned upon Ashoka. So he famously decided to renounce armed conquests and dedicated the rest of his life to non-violence and dharma-vijaya, victory through the right principles.

Our history books are filled with anecdotes like these that attempt to inculcate an ethical understanding of the greys between war and peace. If asked whether war is good or bad, the majority will side with the latter. But in reality, we enjoy consuming glorified versions of war. There is a reason why more than 130 films of World War I and at least 1,300 of World War II exist. We love watching war films and rooting for the right side. The thrill of watching the acclaimed 1917 lies in the fact that it seems like a single-take film crafted to immerse audiences in the experience of war. As we make more and more war movies, we also expand our appetite for consuming the spectacle of war.

In modernity, as wars flood both our books and newspapers, the words perception has been normalised, especially in more privileged and developed societies. In the ancient age, the world fought 24 wars, and at least in the medieval era. However, in modern times since the Great Wars of Italy in the 15th century the world has fought more than 269 wars.

However, has the glorification of war in our films and its trivialisation in our newsfeed changed its meaning forever? In 2019, when a member of the Pakistan-based terror group Jaish-e-Mohammed killed more than 40 Indian soldiers in Kashmir, many Indian television anchors issued provocative messages on nationalism, calling for war. We want revenge, not condemnation. It is time for blood, the enemys blood, said Arnab Goswami, infamous for his aggressive, pro-establishment brand of journalism. In another episode, Goswami invited his viewers to send an SMS on whether India should go to war with Pakistan.

Similarly, tourists have been called out for clicking disrespectful selfies at the Auschwitz Museum and the Holocaust Memorial. There are better places to learn how to walk on a balance beam than the site which symbolises deportation of hundreds of thousands to their deaths, the museums managers tweeted.

Both these instances indicate that our society has been overwhelmed with information and infotainment options around war, and has thus become hardened against the act of war; the meaning of the word today is far from what it used to be. So before advancing an argument on whether war is on the decline or not, it might be a good idea to start by defining what it really means.

According to the Cambridge dictionary, war is simply armed fighting between two or more countries or groups. This definition encompasses violent attacks between two groups instead of the more traditional idea of war as a means of conquest. During World War II, an estimated 70-85 million people died around 3% of the worlds population at the time. We can safely argue that todays conflicts between Armenia and Azerbaijan, Turkey and Russia, India and Pakistan, etc., have claimed fewer lives. But this wouldnt mean human suffering has decreased or that modern-day conflicts should not be a matter of concern for world leaders.

However, it also indicates that while the scale of war is declining, the number of violent conflicts is certainly not. In ancient agricultural societies, human violence caused about 15% of all deaths; in the early 21st century, it was responsible for about 1% of global mortality. Thats good news.

The US Navy battleship USS Pennsylvania leading USS Colorado and the cruisers USS Louisville, USS Portland and USS Columbia into Lingayen Gulf, Philippines, in January 1945. Photo: US Navy

The linguist, philosopher and critic Steven Pinker is often credited with being one of the first people to claim that war is gone. He famously said that today we may be living in the most peaceable era in our species existence. One reason for his this deduction is the rise of democratic societies restricted by laws on the use of force. Violence is no longer seen as the only way of solving problems. Another reason is the growing trade between neighbouring nation-states.

For example, in 2017, after a month-long standoff between India and China over the disputed territory of Doklam, both finally agreed to pull their troops back. What happened? One obvious reason is that China is Indias largest trading partner. As of 2018, Indias imports from China stood at $70.32 billion, while exports to the country were valued at $16.75 billion. That is a lot of business to lose for both countries, so it made perfect sense to deescalate.

Counties armed with nuclear power look at the tendency of war as a means to achieve peace. This makes them look at alternatives to resolve conflicts which lead us to believe that war is disappearing along with the civilising process. It is said that during the Cold War, both sides were building weapons that were considered most useful if never used.

But its not all rosy. Bear Braumoeller, a political scientist at Ohio State University, attributes Pinker-like beliefs to random luck, and adds that that luck can run out any time. In his book, Only the Dead: The Persistence of War in the Modern Age (2019), Braumoeller argued that the belief that war is disappearing has created a false sense of security and that the escalatory propensity of war still exists. The recent tiff between the US and North Korea comes to mind. There are many such examples of war-like escalations, including between Peru and Ecuador, over a disputed soccer match in 1995, and between Greece and Turkey over an uninhabited rock. It would be fair to say that although the probability is low, the world still sits on ticking time bomb when it comes to the next big war.

The Israeli historian Yuval Noah Harari returned this debate to the fore with his book Homo Deus (2015), in which he said the end of war is one of the good news of our times. He argues that throughout history, international relations were governed by the law of the jungle, where peace was in a precarious state and war always remained an option. This law of the the jungle has finally been broken, he wrote. Its true. Today, the fabric of society is such that governments and corporations seldom consider war as a likely event while taking geopolitical decisions. Countries have realised that wars dont even make economic sense anymore. Rather than resorting to violence, they tend towards mutual benefit by developing trade and skill-based economies. The rise of capitalism across the world has made countries look at even peace as a profitable investment.

The Korean War in 1950-1953 was the last one in which tensions grew between superpowers on both sides (notwithstanding escalations by proxy, like Saddam Hussains invasion of Iran in the 1980s; he had military and economic support from both the US and the Soviet Union). While it is true that in the last 75 years the likelihood of World War III has been close to zero, it is also true that war has been changing its shape and form. The USs war on terror is one example. This war, launched in the wake of the 9/11 attacks, cost at least 480,000 lives and $5.9 trillion, and precipitated a host of problems in Afghanistan, Pakistan, Iraq, Syria and Yemen.

US Marines retreating during the Battle of the Chosin Resevoir in the Korean War, c. 1953. Photo: US Government

According to Harari, terrorism is a show. Terrorists stage a terrifying spectacle of violence that captures our imagination and makes us feel as if we are sliding back into medieval chaos. In most cases, overreaction to terrorism poses a far greater threat to our security than the terrorists themselves, he writes. It can, therefore, be extrapolated that Americas overreaction has cost peace in many parts of the globe and has even led to a counter-reaction in most cases.

Even if we were to say today that violence around the world is on the decline, the trend doesnt necessarily hold true for the future especially with attacks like those in Afghanistan becoming more common. In fact, scientists have warned of a new kind of war called hybrid warfare. It combines chemical weaponry, random but targeted killings, terrorism, cyber warfare, and other indirect means like fake news, diplomacy and electoral interventions to achieve its goals. India and Pakistan, for example, have been fuelling violence in Baluchistan and Kashmir respectively to indirectly take on each other. Today, politicide and homicide kill more people than wars. ISISs genocidal attacks on the Yazidi, the Boko Harams attacks against Nigerian civilians, and the rise of neo-Nazis in Germany indicates that war is far from over.

Perhaps the solution lies in a sublime line from Leo Tolstoys classic novel War and Peace (1869): If everyone fought for their own convictions, there would be no war. Simply, instead of believing in someone elses ideas of nationalism and pride, if one stands up for ones own ideals, ambitions and beliefs, war would end. This is probably what Emperor Ashoka also experienced when he renounced violence and followed his quest for inner peace, eventually leading to the spread of Buddhism across Asia.

Prerna Lidhoo is a journalist based in Delhi. She tweets @PLidhoo.

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Its Anatomy Keeps Changing But What Will it Take for War to End? - The Wire