The Southern Poverty Law Center’s New Enemy: Americans Who Accept Biology – Quillette

The Montgomery, Alabama-based Southern Poverty Law Center (SPLC) was founded in 1971 with a mission to fight poverty and racial discrimination. Its early litigation campaigns, which targeted the Ku Klux Klan and other overtly racist organizations, met with success, and the group soon came to be seen as an authoritative source in regard to right-wing extremism more generally.

Another form of expertise the organization developed was in the area of marketingespecially when the market in question consisted of deep-pocketed urban liberals. As former SPLC staffer Bob Moser reported in a 2019 New Yorker article, the group has consistently taken on attention-grabbing urgent-seeming causes that its leaders knew could be leveraged as a means to gain publicity andmore importantlydonations. Its no coincidence that the SPLCs co-founder and long-time fundraising guru, Morris Dees, had previously operated a direct-mail business that sold cookbooks and tchotchkes. Whether youre selling cakes or causes, its all the same, Dees told a journalist in 1988.

The Reckoning of Morris Dees and the Southern Poverty Law Center

The work at the S.P.L.C. could be meaningful and gratifying. But it was hard, for many of us there, not to feel like wed become pawns in what was, in many respects, a highly profitable scam.

Dees big fundraising break at the SPLC came when he got access to the direct-mail list from the 1972 presidential campaign of Democrat George McGovern. The SPLC co-founder went on to maximize the SPLCs revenues through what would now be known as targeted methods. According to one former legal colleague, for instance, Dees rarely used his middle nameSeligmanin SPLC mailings, except when it came to Jewish zip codes.

Thanks to Dees slick marketing expertise, the SPLC was eventually taking in more money than it paid out in operational expenses. (As of October 2022, its endowment fund was valued at almost US$640 million.) But over time, his hard-sell tactics began to alienate co-workers, as there was an obvious disconnect between the real class-based problems they observed in society and the fixations of the nave northern donors whose wallets Dees was seeking to pry open.

I felt that [Dees] was on the Klan kick because it was such an easy targeteasy to beat in court, easy to raise big money on, former SPLC attorney Deborah Ellis told Progressive writer John Egerton. The Klan is no longer one of the Souths biggest problemsnot because racism has gone away, but because the racists simply cant get away with terrorism any more.

How the Southern Poverty Law Center got Rich Fighting the Klan

SPLCs current meltdown was a long time coming. Our 1988 magazine story investigates the spectacular success of the center and the pivotal role of the fundraising gladiator, Morris Dees.

On March 14, 2019, Deesby now 82 years old, but still listed as the SPLCs chief trial lawyerwas fired amid widespread rumors that hed been the subject of internal sexual-harassment accusations. His affiliation was scrubbed from the groups web site; and the organizations president, Richard Cohen, cryptically (but damningly) declared that, when one of our own fails to meet [SPLC] standards, no matter his or her role in the organization, we take it seriously and must take appropriate action. (Less than two weeks later, Cohen himself left the organization, casting his resignation as part of a transition to a new generation of leaders.)

In describing his tenure at the SPLC during the early 2000s, Moser argued that the very structure of the organization betrayed its hypocrisy: Here was an entity dedicated to social justice (as we would now call it), yet which was run by an extremely well-paid, almost exclusively white, corps of lawyers, administrators, and fund-raisers who ruled over a mixed-race corps of junior staff. As far back as the 1980s, Dees was openly admitting that he saw the fight against poverty as pass, and admitted that the P in SPLC was an anachronism. Jaded staff began ruefully referring to their own flashy headquarters as the Poverty Palace.

Dees and Cohen may have left the Poverty Palace, but the SPLCs tendency to betray its founding principles clearly remains a problem, as illustrated by a new SPLC report released under the auspices of what the group dubs Combating Anti-LGBTQ+ Pseudoscience Through Accessible Informative Narratives. (This verbal clunker seems to have been reverse-engineered in order to yield the acronym, CAPTAIN.)

The report purports to demonstrate the perils of anti-LGBTQ+ pseudoscience and anti-trans narratives and extremism. Much like the dramatically worded hard-sell direct-mail campaigns that the SPLC started up under Dees, its marketed as a matter of life and death: According to the deputy director of research for the SPLCs Intelligence Project, the anti-LGBTQ+ pseudoscience uncovered by the SPLC has real-life, often life-threatening consequences for trans and non-binary people.

At this point, it should be stressed that there is certainly nothing wrong with the SPLCor anyone elsecampaigning for the legitimate rights of people who are transgender. Such a campaign would be entirely in keeping with the SPLCs original liberal ethos. Just as no one should be denied, say, an apartment, a marriage license, or the right to vote based on his or her race, religion, sex, or sexual orientation, no trans person should be denied these rights and amenities simply because he or she experiences gender dysphoria.

But the SPLCs report hardly confines itself to such unassailable liberal principles. The real point of the project, it seems, was to catalogue and denounce public figures whove expressed dissent from the most extreme demands of trans-rights activistsspecifically, (1) the demand that children and adolescents who present as transgender must instantly be affirmed in their dysphoric beliefs, even if such affirmation leads to a life of sterility, surgical disfigurement, drug dependence, and medical complications; and (2) the demand that biological men who self-identify as women must be permitted unfettered access to protected womens spaces and sports leagues.

The SPLCs authors seek to cast their ideological enemies as hate-addled reactionaries whose nefarious activities must be understood as part of the historical legacy of white supremacy and the political aims of the religious right. And it is absolutely true that some of the organizations they name-check are hard-right, socially conservative outfits that endorse truly transphobic (and homophobic) beliefs.

But many of the supposed transphobes targeted by the report arent even conservativelet alone members of the religious right. In a multitude of cases, theyre simply parents, therapists, and activists who argue the obvious fact that human sexual biology doesnt evanesce into rainbow dust the moment that a childor middle-aged manasserts that he or she was born in the wrong body.

Its also interesting to note who gets left out of the SPLCs analysis. The most influential figures leading the backlash against (what some call) gender ideology are women such as author J.K. Rowling and tennis legend Martina Navratilova, both of whom come at the issue from explicitly feminist perspectives. Being successful public figures, neither woman needs a cent from the conservative think tanks that the SPLC presents as being back-office puppet-masters of the alleged anti-trans conspiracy outlined in the CAPTAIN report.

In keeping with the conspiracist motif that runs through the document, the authors have provided spider-web diagrams that set out the connections binding this (apparently) shadowy cabal. In this regard, it seems that Quillette itself served as one of the SPLCs sources: In a section titled, Group Dynamics and Division of Labor within the Anti-LGBTQ+ Pseudoscience Network, the authors footnote an August 23, 2023 podcast for Quillette, wherein

Weve chosen to highlight this particular (typo-riddled) text from the report not just because of the absurd suggestion that our publication has enlisted in an imaginary anti-LGBTQ+ pseudoscience network, but also because the above-quoted roll call of supposed gender villains illustrates the intellectual dishonesty that suffuses the whole report.

Lets go through the references one by one, in the order in which they are presented. The Gender Dysphoria Alliance (GDA) is a group led by people who are themselves transgender, and who are concerned about the direction that gender medicine and activism has taken. Are we to imagine that its members are directing transphobiaagainst themselves? Lisa Littman, formerly of Brown University, is a respected academic whos published a peer-reviewed analysis of Rapid Onset Gender Disorder. Ray Blanchard is a well-known University of Toronto psychiatrist. The Archives of Sexual Behavior is a peer-reviewed academic journal in sexology. Michael Bailey is a specialist in sexual orientation and gender nonconformity at Northwestern University. Colin Wright is a widely published writer (including at Quillette) with a PhD in evolutionary biology from UC Santa Barbara. (The SPLCs claim that he is in a relationship with journalist Christina Buttons, who also writes about gender issues, is completely true. But the fact that the group saw fit to report this fact as if it were evidence of sinister machinations says far more about the reports authors than it does about either Wright or Buttons.) FAIR, the Foundation Against Intolerance & Racism, is a classically liberal group led by a Harvard Law School graduate named Monica Harris. Do any of these people or groups sound like extremists?

The fact that the SPLC is attempting to market its report as a blow against the anti-LGBTQ+ movement, writ large, is itself quite laughable, since many of the activists whove been arguing for a more balanced approach to gender rights are themselves either gay (as with Navratilova and Julie Bindel) or (as with the founders of the GDA) transgender.

Others on the SPLC gender-enemies list are author Abigail Shrier, and therapists Sasha Ayad, and Stella OMalley. These women openly broadcast their views in best-selling books, as well as mainstream magazines and newspapers. The idea that the SPLC has successfully exposed these women through some kind of investigation, as suggested by the title thats been slapped on the CAPTAIN report, would be ludicrous even if theyd said anything scandalous (which they havent).

And what course of future action does the SPLC endorse? For one, it concludes that educators should stigmatize gender-critical views as analogous to racism, sexism, and heteronormativity. The report's authors also want academic journals to sniff out groups that espouse an anti-LGBTQ+ ideology (as that latter term is speciously defined by the SPLC). And in a final flourish, the group urges reporters to be aware of the narrative manipulation strategies and the cooptation of scientific credentials and language by anti-trans researchers when sourcing stories about trans experiences.

With this last point, we get to the real nub: The apparent goal is for this report to be read as a catalogue of people, ideas, and groups that must be shunned. Indeed, the authors explicitly cite the work of one Andrea James, a once-respected arts producer who, as Jesse Singal has documented, now runs a creepy (stalker is the word Singal uses) web site called Transgender Map, which lists personal details of anyone whom James deems a gender heretic. When it comes to one-on-one communication, James manner of dealing with critics is exemplified by an email sent to bioethicist Alice Dreger, in which James referred to Dregers then-five-year-old son as a womb turd.

The rage behind Transgender Map

An activist media ecosystem enabled Andrea James

One way to describe the CAPTAIN report is as an SPLC-branded rehash of the information contained on Transgender Map. And one can understand why the authors thought that such a gambit might work. The SPLC already publishes other curated lists of hatemongerse.g., its Hatewatch service, Hate Map, and Intelligence Report. It wasnt such a long shot to imagine that this new report might convince readers to treat the listed Anti-LGBTQ+ Pseudoscience Network acolytes as equally disreputable.

But if that was the authors goal, it doesnt seem to have been achieved. The SPLC report landed with something of a thudand has attracted little attention on social media except insofar as it was mocked by its intended targets.

This may have something to do with the reports timing. For several years now, a backlash against this kind of gender agitprop has been building within many of the same liberal and progressive circles that the SPLC has traditionally targeted for donations. The trend is reflected by the rise of such groups as the LGB Alliance, a coalition of lesbian, gay, and bisexual people who are fed up with the ideological takeover of LGBT groups by a militant subset of trans activists.

The same trend is playing out internationally. While the SPLC does its best to heap blame on Americas conservative Christians, many of western Europes governments (none of which are in thrall to the Heritage Foundation or the Charles Koch Foundation) have been following a more gender-critical path for years.

Just a week after the SPLC put out its report, in fact, the UK government published new guidelines advising teachers that they have no duty to automatically affirm a childs assertion that he or she is transgender; and that, in considering such situations, teachers should speak with a childs parents and consider whether the child is under undue influence from social media or peers. Sweden, Finland, and Norwayhardly bastions of Christian conservatismhave also rolled back policies that rush children into transition. In Canada, several provinces have recently enacted rules that require parents to be notified when a child seeks to transition, even in the face of a sustained media campaign that repeats lurid claims to the effect that such policies will cause an epidemic of trans suicides. Are all of these foreign governments also complicit in the vast junk-science and disinformation campaign against trans people that the SPLC claims to have exposed?

The SPLC would hardly be the first progressive organization whose reputation has suffered by going all-in on the gender issue. The American Civil Liberties Union, which also was rooted in traditional liberal values before succumbing to more faddish progressive tendencies, has attracted ridicule due to its parroting of slogans such as men who get their periods are men, and the claim that males have no unfair advantage over females in sports.

These organizations have never been shy about angering conservatives and reactionaries; indeed, they wear such anger as a badge of pride. But their cultish refusal to engage with the reality of biological sex also antagonizes progressive feminists seeking to protect female spaces from biological men, and LGB activists who see the attempted erasure of sex-based attraction as a species of progressive homophobia.

Which is to say that the SPLCs report seems not only intellectually dishonest, but also self-destructive. While the SPLC leaders who green-lit this project once may have been able to bank on the popularity of pronoun checks and esoteric gender identities among the wealthy white coastal progressives who comprise the bulk of their donors, this is an ideological movement thats decidedly past its peak. Its a marketing error that the savvy Dees likely never would have made.

The SPLC obviously does a lot more than lend its name to sloppily edited gender propaganda: A review of its press feed shows that it still has staff working traditional legal beats such as voters rights, police accountability, and humane treatment for prisoners. But when an organization publishes misleading materials in regard to one issue, the natural effect is to raise serious questions about the groups values and credibility more generallyquestions that SPLC supporters will want to think about the next time one of the groups fundraisers hits them up for a donation.

View post:

The Southern Poverty Law Center's New Enemy: Americans Who Accept Biology - Quillette

50-year-old muscles just can’t grow big like they used to the biology of how muscles change with age – Yahoo News

There is perhaps no better way to see the absolute pinnacle of human athletic abilities than by watching the Olympics. But at the Olympics and at almost all professional sporting events you rarely see a competitor over 40 years old and almost never see a single athlete over 50. This is because with every additional year spent on Earth, bodies age and muscles dont respond to exercise the same as they used to.

I lead a team of scientists who study the health benefits of exercise, strength training and diet in older people. We investigate how older people respond to exercise and try to understand the underlying biological mechanisms that cause muscles to increase in size and strength after resistance or strength training.

Old and young people build muscle in the same way. But as you age, many of the biological processes that turn exercise into muscle become less effective. This makes it harder for older people to build strength but also makes it that much more important for everyone to continue exercising as they age.

The exercise I study is the type that makes you stronger. Strength training includes exercises like pushups and situps, but also weightlifting and resistance training using bands or workout machines.

When you do strength training, over time, exercises that at first felt difficult become easier as your muscles increase in strength and size a process called hypertrophy. Bigger muscles simply have larger muscle fibers and cells, and this allows you to lift heavier weights. As you keep working out, you can continue to increase the difficulty or weight of the exercises as your muscles get bigger and stronger.

It is easy to see that working out makes muscles bigger, but what is actually happening to the cells as muscles increase in strength and size in response to resistance training?

Any time you move your body, you are doing so by shortening and pulling with your muscles a process called contraction. This is how muscles spend energy to generate force and produce movement. Every time you contract a muscle especially when you have to work hard to do the contraction, like when lifting weights the action causes changes to the levels of various chemicals in your muscles. In addition to the chemical changes, there are also specialized receptors on the surface of muscle cells that detect when you move a muscle, generate force or otherwise alter the biochemical machinery within a muscle.

In a healthy young person, when these chemical and mechanical sensory systems detect muscle movement, they turn on a number of specialized chemical pathways within the muscle. These pathways in turn trigger the production of more proteins that get incorporated into the muscle fibers and cause the muscle to increase in size.

These cellular pathways also turn on genes that code for specific proteins in cells that make up the muscles contracting machinery. This activation of gene expression is a longer-term process, with genes being turned on or off for several hours after a single session of resistance exercise.

The overall effect of these many exercise-induced changes is to cause your muscles to get bigger.

While the basic biology of all people, young or old, is more or less the same, something is behind the lack of senior citizens in professional sports. So what changes in a persons muscles as they age?

What my colleagues and I have found in our research is that in young muscle, a little bit of exercise produces a strong signal for the many processes that trigger muscle growth. In older peoples muscles, by comparison, the signal telling muscles to grow is much weaker for a given amount of exercise. These changes begin to occur when a person reaches around 50 years old and become more pronounced as time goes on.

In a recent study, we wanted to see if the changes in signaling were accompanied by any changes in which genes and how many of them respond to exercise. Using a technique that allowed us to measure changes in thousands of genes in response to resistance exercise, we found that when younger men exercise, there are changes in the expression of more than 150 genes. When we looked at older men, we found changes in the expression of only 42 genes. This difference in gene expression seems to explain, at least partly, the more visible variation between how young and old people respond to strength training.

When you put together all of the various molecular differences in how older adults respond to strength training, the result is that older people do not gain muscle mass as well as young people.

But this reality should not discourage older people from exercising. If anything, it should encourage you to exercise more as you age.

Exercise still remains one of the most important activities older adults can do for their health. The work my colleagues and I have done clearly shows that although the responses to training lessen with age, they are by no means reduced to zero.

We showed that older adults with mobility problems who participate in a regular program of aerobic and resistance exercise can reduce their risk of becoming disabled by about 20%. We also found a similar 20% reduction in risk of becoming disabled among people who are already physically frail if they did the same workout program.

While younger people may get stronger and build bigger muscles much faster than their older counterparts, older people still get incredibly valuable health benefits from exercise, including improved strength, physical function and reduced disability. So the next time you are sweating during a workout session, remember that you are building muscle strength that is vital to maintaining mobility and good health throughout a long life.

This article is republished from The Conversation, a nonprofit, independent news organization bringing you facts and trustworthy analysis to help you make sense of our complex world.If you found it interesting, you could subscribe to our weekly newsletter.

It was written by: Roger Fielding, Tufts University.

Read more:

Roger Fielding receives funding from USDA, NIH, Biophytis, Nestle', Lonza.

Read the original:

50-year-old muscles just can't grow big like they used to the biology of how muscles change with age - Yahoo News

In 2023, big projects create ‘satellite maps’ of cell biology – BioWorld Online

23 in review

If we unraveled the DNA of the 46 chromosomes of a single human cell, it would barely measure 2 meters. If we did the same with the rest of the body, if we aligned the 3 billion base pairs of its 5 trillion cells, we could travel the distance from the Earth to the Sun more than 100 times. It seems unreachable. However, that is the unit of knowledge of the large sequencing projects achieved in 2023. From the generation of the human pangenome to cell-by-cell maps of the brain and kidneys, scientists this year have completed several omics collaborative projects stored in large international databases. Now, whats the plan?

Read more here:

In 2023, big projects create 'satellite maps' of cell biology - BioWorld Online

Reindeer biology is super weird and new research helps explain why – Salon

Reindeer are traditionally associated with Christmas lore and, if you follow the latest research on reindeer, you can see that there is a good reason for this. While real-life reindeer do not fly, they have a number of other freaky biological traits, and like Rudolph's nose, recent research is illuminating what makes reindeer tick.

For instance, a study in the journal Current Biology revealed that reindeer chew their cud while sleeping, an intriguing way in which reindeer eating habits are opposite those of humans. While humans are advised to avoid eating shortly before going to sleep, these Norwegian reindeer who are in the process of ruminating have brain waves similar to those present during NREM (non-rapid eye movement) sleep; in other words, when they undergo the complex process of chewing and digesting their food, the reindeer brains undergo a sleep-like experience. They even derive a benefit from this for periods when they are not ruminating.

"Having eaten all the oats the kids left out for them, the reindeer will need time to ruminate (chew their cud) and catch up on the sleep they didnt get while delivering presents," Dr. Gabi Wagner, a chronobiologist from the Norwegian Institute of Bioeconomy Research, told Salon by email, both literally and figuratively tongue in cheek.

The more reindeer ruminate, the less additional non-REM sleep they need, first author and neuroscientist Melanie Furrer of the University of Zurich, said in a statement. We think it's very important that they are able to save time and cover their sleep and digestive needs at the same time, especially during the summer months.

The reindeer being monitored are owned by the Arctic University of Norwayin Troms, where they live in outdoor enclosures that resemble that of wild animals but they have also grown accustomed to humans.

Want more health and science stories in your inbox? Subscribe to Salon's weekly newsletter Lab Notes.

"To protect the health of Rudolph's eyes, kids might want to think about orange juice and carrots as ideal treats."

"To help them get familiar with us, we spent a lot of time just being with them," Wagner explained. "Thanks to all these long term preparations, the animals accepted that we glued the electrodes onto their skin to measure brain activity (EEG). This is a non-invasive method used in the childrens hospital in Zuerich, where first author Melanie works." Wagner added that surveillance cameras enabled the scientists to monitor the reindeer remotely.

It's not just reindeer sleep habits that are odd, but also their vision. Namely, they can detect ultraviolet (UV) light, which is unusual for most mammals. Dr. Nathaniel J. Dominy, an anthropologist from Dartmouth College, explained that human eyes can be damaged by seeing UV light, which is why they block it as much as they can.

"But ascorbic acid (Vitamin C) is a great way to repair UV damage and reindeer eyes have lots of it," Dominy explained. "So, to protect the health of Rudolph's eyes, kids might want to think about orange juice and carrots as ideal treats."

To make matters even more mysterious, scientists aren't sure why reindeer can see UV light in the first place. Dominy's research on the matter, recently published in the journal i-Perception, proposes that it helps Scottish reindeer feast on their primary food source, lichen.

"In contrast to every other species of ruminant, reindeer graze on lichens, especially during winter," the study explains. "The idea that reindeer use UV vision to detect vegetation amid snow was suggested almost a decade ago, with evidence that vascular plants but not lichens are visually distinctive in snow."

While those authors studied a type of lichen that reindeer do not eat, however, Dominy and the other contributors to his study investigated Cladonia rangiferina, which reindeer very much enjoy. While it was difficult for the researchers to spot this lichen amidst the spring snowmelt with just their human eyes, their spectral data revealed that lichen could be very apparent to reindeer during the twilight.

"They also cast new light on the benefits of a luminescent nose it may light the way for Santa to see by, but it is Rudolph's blue-eyes that allow him to find dinner after a long Christmas season," the Dominy and his co-authors write. If anything, he added, the bigger enigma is why reindeer enjoy this lichen, which is much less nutritious than the plants preferred by large herbivores like reindeer.

"Smaller mammals (think rabbits, pikas) can eat lichens, but their caloric needs are far less than, say, a moose or bison. A reindeer's ability to subsist on lichens is a mystery an animal of its size shouldn't be able to do it," Dominy explained. "But it is mainly a winter phenomenon, suggesting lichens are a food of last resort."

Dominy had one other observation about how the science of light can inform reindeer behavior on Christmas, drawing on a 2015 scientific articlefor children he wrote explaining Rudolph the reindeer's iconic red nose.

"Although rare, red luminescent noses are optimal for human aviation under foggy conditions," Dominy told Salon. "Red light travels farther, or rather scatters less, than other colors, which is why airports and towers use red blinking lights. So Rudolph's red nose is ideal for Santa's vision and need for safe navigation at night, whereas Rudolph's vision is optimal for detecting his favorite food under winter twilight."

Wagner also had a Christmas-related observation about reindeer that related to her study on their rumination and sleep habits.

"As reindeer do not sleep more in winter than in summer and also do not eat as much, they should have enough time to bring the presents," Wagner pointed out.

Read the rest here:

Reindeer biology is super weird and new research helps explain why - Salon

Dermatology Times 2023 In Review: NP and PA News – Dermatology Times

Physician Assistant Ranked as 4th Best Job in 2023

The need for physician assistants is expected to increase.

Atopic dermatitis is not a "one-size-fits-all" condition.

Miller shares upcoming news from the SDPA and important legislative updates for dermatology physician assistants.

Dermatology advanced practice providers work alongside physicians to improve patient care and access.

Discussing photoprotection with patients is crucial as Melanoma May" kicks off this month.

Jennifer Orozco, DMSc, PA-C, DFAAPA, oversees the American Academy of Physician Associates and advocates for the role of PAs.

Bush revealed what she is looking forward to in the coming year and the goals she wants to accomplish.

From bug bites to poison ivy, the skin can be exposed to a large spectrum of trouble while patients spend extended time outside.

NPs and PAs in dermatology are encouraged to monitor their own cardiovascular health and support their peers.

Renata Block, MMS, PA-C, delves into the important and ever-evolving role of physician assistants in dermatology.

Dermatology Times, the SDPA, and more are celebrating the invaluable contributions of nurse practitioners in dermatology this NP Week (November 12-18).

The approval of Galdermas Restylane Eyelight was one of Martins top highlights of 2023.

For more NP and PA news, click here.

See the original post here:

Dermatology Times 2023 In Review: NP and PA News - Dermatology Times

Dermatology Times 2023 In Review: Acne – Dermatology Times

New Pediatric Perspectives for Acne

Experts at Maui Derm Hawaii offer the latest findings and research in treating acne vulgaris in adolescents.

A new study also explores why the incidence of acne vulgaris is higher in girls than boys.

Study investigators evaluated the blood-brain barrier penetrance and lipophilicity of the narrow-spectrum, third-generation tetracycline-class oral antibiotic used for acne treatment.

Transgender and cisgender patients presenting with acne face differences in acne treatment and prescribing patterns.

Researchers say adolescents and young adults using the dermocosmetic product experienced improvements in their acne and quality of life.

Researchers say sun exposure plays a role in the exposome of acne-prone skin.

Researchers said the drug successfully altered C. acnes strains and more in a recent study.

Researchers said using the injections and mesotherapy in patients with acne more effectively treated their acne.

Researchers said the treatment may improve post-acne erythema.

Julie Harper, MD, shared updated risks and benefits of using spironolactone and oral contraceptives to treat acne in women at SCALE 2023.

Zeichner reviewed his top 3 acne treatment pearls at the Fall Clinical Dermatology Conference for PAs and NPs.

A poster presentation from the Fall Clinical Dermatology Conference for PAs and NPs evaluated the safety and efficacy of tazarotene for acne patients with skin of color.

During pregnancy and lactation, physiological changes occur in the body that can impact the development and management of acne.

With hormonal fluctuations, constantly changing schedules, and various afterschool activities, addressing the specific needs of teenage skin becomes essential to promote a lifetime of proper skin care practices.

Catch up on acne vulgaris treatment pearls from Dermatology Times most recent Frontline Forum series, featuring James Del Rosso, DO; Hilary Baldwin, MD; Neal Bhatia, MD; Christopher Bunick, MD, PhD; and Leon Kircik, MD.

Yale School of Medicine researchers found tetracycline-class antibiotics were the most prescribed acne treatment for adult female patients between 2002 and 2016.

The impact of acne conglobata on individuals underscores the crucial role dermatologists play in providing effective diagnosis, treatment, and emotional support.

The US Food and Drug Administration has approved IDP-126 gel for patients with acne.

The Sun Pharma survey included 1003 respondents with mild to moderate acne.

Read this article:

Dermatology Times 2023 In Review: Acne - Dermatology Times

Reviewing the Top Dermatology Headlines of 2023 – Dermatology Times

FDA Accepts sNDA for Arcutis' Roflumilast Cream 0.15% for Atopic Dermatitis, Sets July 2024 PDUFA Date

The sNDA is supported by positive data from the phase 3 INTEGUMENT-1 and INTEGUMENT-2 trials.

The FDAs PDUFA target date is May 25, 2024.

Immunotherapies, including PD-1 checkpoint inhibitors such as nivolumab, have improved the treatment options for patients with advanced melanoma.

There are currently no FDA-approved therapies for the rare, genetic disease.

Christopher Bunick, MD, PhD, and David Light, CEO of Valisure, weigh in on the proposed formaldehyde ban.

The approved indication makes Wezlana the first approved interchangeable biosimilar to Stelara.

Secukinumab is currently the only IL-17A inhibitor approved for the condition.

The US Food and Drug Administration has approved IDP-126 gel for patients with acne.

The CRL states that additional efficacy data is needed in order to support approval.

Bimekizumab is now the first and only approved IL-17A and IL-17F inhibitor for this indication.

Kyverna Therapeutics can now initiate its phase 1/2 open-label, multicenter study of KYV-101.

The approval provides pediatric patients with a steroid-free topical therapy.

No concerns were cited about the clinical data package, safety, or label of lebrikizumab.

Abeona Therapeutics is seeking Priority Review and approval of the therapy for patients with recessive dystrophic epidermolysis bullosa.

From its clinical study, 97% of patients saw improvement in acne scars after 3 treatment sessions.

The topical cream is the first epidermolysis bullosa treatment to receive Breakthrough Therapy designation from the FDA.

Beremagene geperpavec is the first FDA-approved treatment for DEB, a rare and burdensome disease.

Ritlecitinib is the first and only treatment cleared for adolescents with severe alopecia areata.

Patients can achieve reduced excessive underarm sweating after one in-office treatment.

The expanded approval is based on data from a recent phase 3 clinical trial.

The picosecond system has previously been approved for treating acne scarring, pigmented lesions, tattoo removal, and wrinkles.

Verricas VP-102 is the first FDA-approved treatment for molluscum lesions.

Jared Gollob, MD, Chief Medical Officer of Kymera Therapeutics, spoke with Dermatology Times to discuss these trial results.

Germany will be the first country where lebrikizumab will be available for prescription, with a subsequent rollout across European countries throughout 2024.

Timber Pharmaceuticals has been developing TMB-001 for the treatment of congenital ichthyosis.

This month's cover feature delves into the new applications and use of AI in dermatology and considers how AI can support clinicians rather than hinder them.

See any important headlines we may have missed this year? Share with us by emailing our team at DTEditor@mmhgroup.com.

See the original post here:

Reviewing the Top Dermatology Headlines of 2023 - Dermatology Times