Monthly Archives: October 2022

Cell Biology

RAPT Therapeutics Strengthens Leadership Team with Two New Key Hires – BioSpace

SOUTH SAN FRANCISCO, Calif., Sept. 28, 2022 (GLOBE NEWSWIRE) -- RAPT Therapeutics, Inc.(Nasdaq: RAPT), a clinical-stage, immunology-based biopharmaceutical company focused on discovering, developing and commercializing oral small molecule therapies for patients with significant unmet needs in inflammatory diseases and oncology, today announced the appointment of Jennifer Nicholson as Senior Vice President of Regulatory Affairs and Quality Assurance and Adnan Rahman as Vice President of Commercial.

It is a pleasure to welcome both Jennifer and Adnan to the RAPT leadership team at this exciting time of growth for the Company, said Brian Wong, M.D., Ph.D., President and Chief Executive Officer of RAPT Therapeutics. The combination of their regulatory, commercial and marketing expertise is invaluable as we advance our RPT193 program into late stage trials in atopic dermatitis and asthma and continue development of FLX475 program in multiple cancer indications.

Jennifer Nicholson Jennifer brings over 20 years of biotechnology and pharmaceutical industry regulatory expertise, with significant experience across all stages of development in oncology including hematologic malignancies and solid tumors. Most recently, she served as Vice President of Regulatory Affairs at Kronos Bio. Prior to Kronos Bio, she was Head of Global Regulatory Science at Acerta Pharma, a member of the AstraZeneca Group. Jennifer was the Global Regulatory Lead for the Calquence (acalabrutinib) US NDA, which was granted accelerated approval in 2017, as well as for subsequent global filings. Prior to joining Acerta, Jennifer was Senior Director of Regulatory Affairs at Bavarian Nordic, where she focused on immuno-oncology and vaccine products. Earlier in her career, Jennifer worked as the Global Regulatory Lead on various hematology and oncology products at Jazz Pharmaceuticals, Onyx Pharmaceuticals and Genentech. Jennifer holds a B.S. in Biochemistry and Cell Biology from the University of California, San Diego and an M.H.A. from the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill.

Adnan RahmanAdnan brings over 20 years of biopharmaceutical commercial and marketing expertise. Most recently, he served as Global Commercial Lead of Dermatology at Arena Pharmaceuticals, acquired by Pfizer., where he led global commercial strategy for its principal asset, Etrasimod, in atopic dermatitis and alopecia areata. Prior to Arena Pharmaceuticals, he was U.S. Commercial Director of XGEVA (denosumab) at Amgen and held various senior marketing positions in oncology, bone health and inflammation business units. Earlier in his career, Adnan held various marketing positions at Pharmacia and Procter & Gamble. Adnan holds an M.B.A. from Rutgers University and an M.A and B.A. in Electrical Engineering from University of Cambridge.

About RAPT Therapeutics, Inc.RAPT Therapeutics is a clinical stage immunology-based biopharmaceutical company focused on discovering, developing and commercializing oral small molecule therapies for patients with significant unmet needs in inflammatory diseases and oncology. Utilizing its proprietary discovery and development engine, the Company is developing highly selective small molecules designed to modulate the critical immune drivers underlying these diseases. RAPT has discovered and advanced two unique drug candidates, RPT193 and FLX475, each targeting C-C motif chemokine receptor 4 (CCR4), for the treatment of inflammation and cancer, respectively. The Company is also pursuing a range of targets that are in the discovery stage of development.

RAPT Media Contact:Aljanae Reynoldsareynolds@wheelhouselsa.com

RAPT Investor Contact:Sylvia Wheelerswheeler@wheelhouselsa.com

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RAPT Therapeutics Strengthens Leadership Team with Two New Key Hires - BioSpace

Cell Biology

PostDoctoral Research Assistant in Single Cell Mass Spectrometry job with UNIVERSITY OF SURREY | 310566 – Times Higher Education

Chemistry

Location: GuildfordSalary:34,308 to 42,155 per annumFixed TermPost Type:Full TimeClosing Date: 23.59 hours BST on Sunday 23 October 2022Reference: 067422

The University of Surrey is opening a unique national facility for spatially resolved live single cell omics (SEISMIC). This centre will welcome industry and academic users from across the UK. SEISMIC will use the new cutting-edge Yokogawa SS2000 instrumentation to extract single cells, and even subcellular compartments from cells cultured whilst under microscope observation. Extracted cell contents can then be analysed using mass spectrometry omics at Surrey, and within collaborators. The methodology is also compatible with genome and RNA analysis. The SEISMIC award includes funds for researchers to travel to Surrey to conduct experiments. SEISMIC will enable scientific discoveries in a completely new way in distinct areas including drug discovery, infection, stem cell biology, immunity and ageing.

We are looking for motivated, enthusiastic individuals with excellent interpersonal, academic and technical skills to join our growing team and help us to set up and run SEISMIC. The postholder will help to drive forward the analytical measurement capability to enhance the sensitivity and reproducibility of single cell measurements of proteins, metabolites and lipids. The successful applicants will also work with a variety of users using the research base and will have opportunity to undertake development work too. There are therefore excellent opportunities for publication and career development for team-oriented scientists. You will need at least PhD degree in chemistry, biochemistry or related discipline. Experience in biological mass spectrometry would be preferred.

For enquiries and further information please contact Professor Melanie Baileym.bailey@surrey.ac.uk, Tony Whettona.whetton@surrey.ac.ukor Paul Townsendp.townsend@surrey.ac.uk

or more informationand to apply online, please download the further details and click on the 'apply online' button above.

In return we offer a generous pension, relocation assistance where appropriate, flexible working options including job share and blended home/campus working locations (dependent on work duties), access to world-class leisure facilities on campus, a range of travel schemes and supportive family friendly benefits including an excellent on-site nursery.

Click here to find out more about the benefits we offer to support you.

The University of Surrey is committed to providing an inclusive environment that offers equal opportunities for all. We place great value on diversity and are seeking to increase the diversity within our community. Therefore we particularly encourage applications from under-represented groups, such as people from Black, Asian and minority ethnic groups and people with disabilities.

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PostDoctoral Research Assistant in Single Cell Mass Spectrometry job with UNIVERSITY OF SURREY | 310566 - Times Higher Education

Cell Biology

Research Fellow, Department of Anatomy and Physiology job with UNIVERSITY OF MELBOURNE | 310587 – Times Higher Education

Location:ParkvilleRole type:Full time; Fixed-termfor 12 monthsFaculty: Medicine, Dentistry and Health SciencesDepartment/School:Department of Anatomy and PhysiologySalary:Level A $77,171 $104,717p.a. (pro rata for part-time) plus 17% super

The University of Melbourne would like to acknowledge and pay respect to the Traditional Owners of the lands upon which our campuses are situated, the Wurundjeri and Boon Wurrung Peoples, the Yorta Yorta Nation, the Dja Dja Wurrung People. We acknowledge that the land on which we meet and learn was the place of age-old ceremonies, of celebration, initiation and renewal, and that the local Aboriginal Peoples have had and continue to have a unique role in the life of these lands.

About the Department of Anatomy and Physiology

The Department of Anatomy and Physiology has only recently come into fruition and is an amalgamation between the Departments of Anatomy and Neuroscience and Physiology. Both Departments have long and illustrious history and have come together to produce a Department with a remarkable breadth and depth in research expertise that underpin our key research themes of neuroscience, metabolism and cardiovascular sciences, muscle biology, and cell biology.

The goal of the combined department is to remain at the forefront of scientific research aimed at understanding the structure and function of the human body in health and disease, employing novel and imaginative research methods.

About the Role

The Research Fellow will work within the Wells Laboratory on NHMRC funded research. The role will conduct supervised research using pluripotent stem cells to model macrophage biology. The role will also require the provision of support for research projects and programs within the laboratory, including administration and maintenance and use of information systems.

Responsibilities include:

About You

You will be an experienced research fellow with experience and expertise in pluripotent stem cell culture or human macrophage biology. Your excellent verbal and written communication skills allow you to demonstrate effective research collaboration and engagement. Your strong organisational skills allow you to maintain accurate and detailed laboratory records, and manage competing priorities.

You will also have:

About the University

The University of Melbourne is consistently ranked amongst the leading universities in the world. We are proud of our people, our commitment to research and teaching excellence, and our global engagement.

Benefits of Working with Us

In addition to having the opportunity to grow and be challenged, and to be part of a vibrant campus life, our people enjoy a range of rewarding benefits:

To find out more, visithttps://about.unimelb.edu.au/careers/staff-benefits.

Be Yourself

We value the unique backgrounds, experiences and contributions that each person brings to our community and encourage and celebrate diversity. First Nations people, those identifying as LGBTQIA+, females, people of all ages, with disabilities and culturally and linguistically diverse people are encouraged to apply. Our aim is to create a workforce that reflects the community in which we live.

Join Us!

If you feel this role is right for you, please submit your application including a brief cover letter, your resume and your responses against the selection criteria^ (found in the Position Description) for the role.

^For information to help you with compiling short statements to answer the selection criteria and competencies, please go tohttp://about.unimelb.edu.au/careers/selection-criteria

We are dedicated to ensuring barrier free and inclusive practices to recruit the most talented candidates. If you require any reasonable adjustments with the recruitment process, please contact us athr-talent@unimelb.edu.au.

Please note: To be considered for this role you must havecurrent valid work rights for Australia

osition Description:0057175 - PD.pdf

Applications close:27 Oct2022 11:55 PMAUS Eastern Standard Time

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Research Fellow, Department of Anatomy and Physiology job with UNIVERSITY OF MELBOURNE | 310587 - Times Higher Education

Cell Biology

LBUSD’s Teacher of the Year is a homegrown educator who explains the world with literature Long Beach Post News – Long Beach Post

For Lee Underwood, that moment arrived when he was a high school student at nearby St. John Bosco. One class in particular changed his outlook on the world and inspired the next few decades of his life.

As of last week, that moment has officially come full circle for Underwood, who was recognized as the Long Beach Unified School Districts Teacher of the Year.

An Advanced Placement English Literature and Composition teacher at Millikan High School, Underwood credits his former AP Literature teacher and soccer coach, Jim Cross, for helping spark his love of English and for helping to inspire his career path.

He had this passion for books and teaching poetry that I had just never seen before, recalled Underwood. Me and my angsty self at that time, really connected with the way that he saw poetry as a living thing, as a salve for the troubled soul, or even as a path to self-transformation. So I would read these poets and these books and he would talk about them in ways that really allowed me to make sense of myself.

As the son of a teacher, Underwood spent countless hours in his moms classroom growing up. During his college years as a student at Cal State Long Beach, Underwood again drew inspiration from an English professor, Joe Potts, who helped shape his view on what it means to be a teacher.

He was the one that really got me fired up about pedagogy, Underwood explained. The idea that teachers are artists and their content is their palette; the books they teach, the way that they teach, all those things are very creative processes that the teacher can bring into the classroom. And I really liked that idea. It was at that moment that I decided to go full force into English education in college and pursue my teaching credential.

Underwood started his teaching career at Millikan back in 2006, as a 23-year-old fresh out of his student teaching program. Hes now in his 17th year on campus and has been inspiring his students the same way Mr. Cross did for him.

Underwood said he enjoys cultivating a classroom environment where students can discuss major issues affecting their everyday lives. He acknowledged that those discussions have evolved in the past few years due to the global pandemic and social unrest across the globe. Through literature, hes helped students gain different perspectives on some of the big, complex issues theyre seeing in the world.

The fantastic thing about teaching a humanities class is that its exactly the right place for a student to try to make sense of things that sometimes dont make sense to them, he explained. Ive seen students become much more serious about loss and grief, because its very possible that these students have seen much more of that over the last couple of years than they ever have before. Im in a really unique position to have these students ask these questions of themselves and to guide them through their own thinking using these texts.

One of his former students, Astrid Quirarte, wrote a letter of support for Underwood winning Teacher of the Year while she was attending UC Berkeley to study molecular and cell biology. Her words spoke to Underwoods dedication to his students, and also his willingness to incorporate contemporary issues into his curriculum.

In all my years in school, I have never met a teacher as approachable and caring as Mr. Underwood, Quirarte wrote. Of all Mr. Underwoods attributes, I consider his greatest to be the genuine care he has for all of his students. He would spend extra time after class reading and editing our college application essays, something I greatly benefitted from as a first-generation college student As a Latinx student, I had encountered multiple English classes that incorporated literature that was not representative of the student body and the real-world challenges students faced. Mr. Underwoods integration of contemporary issues regarding discussions of class, race, sex and gender identity was the first time I ever felt seen in the classroom setting.

Underwood described the Teacher of the Year award as an immense honor but alsosomewhat ironicallyhe struggled to put his emotions into words.

It just melts my heart, I dont know how else to explain it, Underwood said. Nothing, no amount of money can take the place of the words that Astrid wrote about me. It makes me realize that this is the right place to be.

Im exactly in the right place.

Local history: No soapProcter & Gambles Long Beach plant closed in 1988

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LBUSD's Teacher of the Year is a homegrown educator who explains the world with literature Long Beach Post News - Long Beach Post

Embryology

Quran and the Modern Science – Brighter Kashmir

Sequential narrative like the book of Genesis.Quran is about as long as the New Testament .In most editions it is about 600 pages in length

The first thing to understand about the Quran is its form. The arabic word Quran literally both 'recitation' and 'reading' . similarly the Quran was both recited orally and written down in book form .The true power of Quran remains in the oral recitation, as it is want to be read aloud and melodiously,

But still the verses were written down on available materials as an aid to memorizing and guarding it, and these were collected and ordered in book form both privately and, at a later stage, institutionally. The Quran was not meant to tell chronological story, and thus the Quran should not be viewed as Sequential narrative like the book of Genesis. Quran is about as long as the New Testament .In most editions it is about 600 pages in length.So, the main theme of writing this article is to spread the message to all people that there is nothing in this world that is not mentioned in our Quran and today we are going to look at one of the miracles or we can say the scientific fact that is mentioned in our quran.Human body is known as the crown of all the creations [Ashraf-ul-Makhlukat] because of its complexity and advancement, lets start by the origin of human body called 'Embryology 'in science. A few years ago a group of Arabs collected all the information about embryology from the Quran and was then translated into English by Dr.Keith Moore, who was the professor of embryology at university of Toronto in Canada, he said that the most of the information concerning embryology mentioned in Quran is perfect ,it is obvious that he could not say whether the statements were true or false, since he himself was not aware of the information mentioned in the Quran. There was no mention of this information in modern writings and studies on embryology. One such verse is: Proclaim ![or read!] in the nameof the lord and cherisher, who created man,out of a [mere]clot of the congealed blood.'{Al Quran 96:1-2}The word ALAQ besides meaning a congealed clot of blood also means something that clings, a leech-like substance . Dr.Keith Moore had no knowledge whether an embryo in the initial stages appear like a leech. To check this out he studied the initial stages of the embryo under a very powerful microscope in his laboratory and compared what he observed with a diagram of a leech and he was astonished at the striking resemblance between the two!.In the same manner, he acquired more information on embryology that was hitherto not known to him, from the Quran Dr.Keith answered about eighty questions dealing with embryological data mentioned in the Quran and Hadith. Nothing that the information contained in the Quran was full agreement with the latest discoveries in the field ofembryology Dr. said 'If i was asked these questions thirty years ago, I would not have been able to answer half of them for lack of information.Dr. Moore had earlier authored the book, 'The Developing Human' After acquiring new knowledge from the Quran he wrote in 1982,the third edition of the same book and was then recipient of an award for the best medical book written by a single author. This book has been translated into several major languages of the world and is used as a textbook of embryology in the first year of medical studies.In 1981, during the Seventh Medical Conference in Dammam, Saudi Arabia,Dr. said,It has been a great pleasure for me to help clarify statements in the Quran about human development. It is clear to me that these statements must have come to Muhammad[PBUH] from almighty ALLAH, because almost all of this knowledge was not discovered until many centuries later. This proves to me that Mohammad[PBUH]must have been a messenger of ALLAH. So,these Hadiths, sayings of Mohammad[PBUH] could not have been obtained on the basis of the scientific knowledge which was not available at that time. It follows that not only is there no conflict between genetics and religion[ISLAM] but in fact Islam may guide science by adding revelation to some of the traditional scientific approaches. Thus the Quranic description matches with the discoveries in modern embryology.

Email:-----------------faizanm1232@gmail.com

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Quran and the Modern Science - Brighter Kashmir

Embryology

Dead fish breathes new life into the evolutionary origin of fins and limbs – EurekAlert

image:The holotype specimen of the fossil Tujiaaspis vividus from 436 million year old rocks of Hunan Province and Chongqing, China. view more

Credit: Zhikun Gai

A trove of fossils in China, unearthed in rock dating back some 436 million years, have revealed for the first time that the mysterious galeaspids, a jawless freshwater fish, possessed paired fins.

The discovery, by an international team, led by Min Zhu of the Institute of Vertebrate Palaeontology and Palaeoanthropology, Bejiing and Professor Philip Donoghue from the University of Bristols School of Earth Sciences, shows the primitive condition of paired fins before they separated into pectoral and pelvic fins, the forerunner to arms and legs.

Until now, the only surviving fossils of galeaspids were heads, but these new fossils originating in the rocks of Hunan Province and Chongqing and named Tujiaaspis after the indigenous Tujia people who live in this region, contain their whole bodies.

Theories abound on the evolutionary beginnings of vertebrate fins and limbs the evolutionary precursors of arms and legs - mostly based on comparative embryology. There is a rich fossil record, but early vertebrates either had fins or they didnt. There was little evidence for their gradual evolution.

First author Zhikun Gai, a University of Bristol alumnus, said: The anatomy of galeaspids has been something of a mystery since they were first discovered more than half a century ago. Tens of thousands of fossils are known from China and Vietnam, but almost all of them are just heads nothing has been known about the rest of their bodies until now.

The new fossils are spectacular, preserving the whole body for the first time and revealing that these animals possessed paired fins that extended continuously, all the way from the back of the head to the very tip of the tail. This is a great surprise since galeaspids have been thought to lack paired fins altogether.

Corresponding author Professor Donoghue said: Tujiaaspis breathes new life into a century old hypothesis for the evolution of paired fins, through differentiation of pectoral (arms) and pelvic (legs) fins over evolutionary time from a continuous head-to-tail fin precursor.

This fin-fold hypothesis has been very popular but it has lacked any supporting evidence until now. The discovery to Tujiaaspis resurrects the fin-fold hypothesis and reconciles it with contemporary data on the genetic controls on the embryonic development of fins in living vertebrates.

Corresponding author Min Zhu of VPP, Beijing, added Tujiaaspis shows the primitive condition for paired fins first evolved. Later groups, like the jawless osteostracans show the first evidence for the separation of muscular pectoral fins, retaining long pelvic fins that reduced to the short muscular fins in jawed vertebrates, such as in groups like placoderms and sharks. Nevertheless, we can see vestiges of elongate fin-folds in the embryos of living jawed fishes, which can be experimentally manipulated to reproduce them. The key question is why did fins first evolve in this way?

Bristols Dr Humberto Ferron used computational engineering approaches to simulate the behaviour of models of Tujiaaspis with and without the paired fins. The co-author said: The paired fins of Tujiaaspis act as hydrofoils, passively generating lift for the fish without any muscular input from the fins themselves. The lateral fin-folds of Tujiaaspis allowed it to swim more efficiently.

Co-author Dr Joseph Keating at Bristol modelled the evolution of paired fins. He said: Fossil jawless vertebrates display a dizzying array of fin types, which has provoked extensive debate about the evolution of paired fins.

Our new analyses suggest that the ancestor of jawed vertebrates likely possessed paired fin-folds, which became separated into pectoral and pelvic regions. Eventually, these primitive fins evolved musculature and skeletal support, which allowed our fishy ancestors to better steer their swimming and add propulsion. It is amazing to think that the evolutionary innovations seen in Tujiaaspis underpin locomotion in animals as diverse as birds, whales, bats and humans.

Paper:

Galeaspid anatomy and origin of vertebrate paired appendages by Zhikun Gai, Qiang Li, Humberto G. Ferrn, Joseph N. Keating, Junqing Wang, Philip C.J. Donoghue and Min Zhu in Nature.

Contact details: Philip Donoghue phil.donoghue@bristol.ac.uk +44 (0)7598189545

Observational study

Animals

Galeaspid anatomy and origin of vertebrate paired appendages

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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Embryology

Jehangir Hospital launches state of the art IVF centre with best facilities – Devdiscourse

Pune (Maharashtra) [India], September 30 (ANI/NewsVoir): Jehangir Hospital Pune launched state-of-the art IVF centre under Jehangir Hospital Assisted reproductive technology or JH-ART . The most modern & state of the art IVF centre [ JH ART ] is equipped fully to offer range of service which include IUI IVF ICSI, Laser Hatching, Egg Donation programme, Onco-fertility for sperm preservation, Social Egg Freezing, Vitrification of Gametes and Embryos, Surrogacy, and donor egg programmes, Ovarian Rejuvenation, PGT-A, pre-implantation genetic testing for aneuploidies and ni (non invasive) PGTA along with Androplus which is a specialized male infertility clinic and Implantation Clinic.

The set up hosts state of the art equipment's along with 3 beds recovery room, Andrology Lab, Embryology Lab with some extremely sophisticated equipment. A well-equipped lab has several types of powerful microscopes, state-of-the-art embryo incubators, and IVF micro tools. In order to grow and develop properly, an embryo requires a complex set of environmental controls at every stage. The air quality in an embryology lab has an enormous effect on the health and viability of embryos. The units in an IVF lab should generate enough air pressure that the air in the room is entirely replaced a minimum of 20 times an hour, hence High-quality air filtration system has been installed in the lab along with the careful light and temperature control.

Embryos are exquisitely sensitive to changes in ambient light and temperature as they develop. Both of these factors are profoundly important. These specialized embryology labs have a vital role to play in IVF, and access to a great IVF lab can greatly raise the chances of success in the fertility treatments along with the team of specialist doctors and the support staff. Jehangir Hospital IVF centre understands the need of an hour and the fact that the standard of an IVF lab plays a crucial role in the treatment cycle and that the quality of an IVF lab is perhaps the most important factor.

Androplus a dedicated male infertility service of JHART highly respects the emotion of 'I WANT TO BE A FATHER', Androplus will focus on helping out men with low sperm counts & azoospermia by various medical treatments and microTESE to achieve their own genetic baby . A specialised IMPLANTATION CLINIC has been installed to evaluate and treat couples with previous IVF or IUI failures. These couples are agonised, they desire a thorough evaluation and specialised one to one care (individualised) for fertility success. Implantation clinic is an unique service installed and long awaited in Pune.

Speaking on the occasion of the launch, Vinod Sawantwadkar, CEO Jehangir Hospital said, "IVF centre was the only missing link in our comprehensive Mother and Child Unit and with Jehangir - ART we now are a complete one stop solution for all the mother and child services. According to Mr Sawantwadkar, The ultimate advantage of IVF is achieving a successful pregnancy and a healthy baby. IVF can make this a reality for people who would be unable to have a baby otherwise: Around 14% of married couples are going through infertility issues and it continues to grow approximately 10% annually. Hence, it is extremely important to have more such centres." Many couples desire planned pregnancy in view of work and career pressures. Fertility preservation by egg, sperm or embryo freezing helps them to take control of 'having the programmed pregnancy suiting their time line' said Dr Sachin Kulkarni, who heads the centre and brings with him a vast experience. Lady suffering from abnormal conditions like endometriosis or early menopause in family can opt for preservation if planning pregnancy late. Fertility preservation at JHART will also be available for women and men who are suffering from cancers and planning chemotherapy. One can safely freeze eggs, sperms prior to chemotherapy and plan pregnancy after the therapy is over added Dr Kulkarni.

A team of experienced IVF & fertility consultants Dr. Sachin Kulkarni , Dr. Sharayu Mohite will be taking care of needy couples. JH ART will provide ethical & evidence based treatment to the couple. Everyone wishes to have baby with their own genetic potential. For female with very low ovarian reserve treatment with ovarian rejuvenation, PRP therapy is available at JHART. For men with azoospermia with microTESE own sperm can be used to have a baby at JH ART.

Shared decision making between doctors and couple after a thorough discussion is the key to success. JHART understands a typical Indian family has inputs from near and dear who also need counselling. FERTILITY COACHING services at JHART will offer family counselling sessions , this will help decrease overall stress and aid a faster pregnancy success .It will also provide the preconception counselling, lifestyle modifications & dietary advice related to fertility.

Being most advanced and accredited tertiary care centre Jehangir hospital will be the best place for fertility treatments for women with heart disorders, diabetes, obesity, hypertension and women planning pregnancy after 40 years. The back-up of trusted medial team will assure safety of all IVF procedures. This story has been provided by NewsVoir. ANI will not be responsible in any way for the content in this article. (ANI/NewsVoir)

(This story has not been edited by Devdiscourse staff and is auto-generated from a syndicated feed.)

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Jehangir Hospital launches state of the art IVF centre with best facilities - Devdiscourse

Embryology

Merck Foundation Together with African First Ladies Mark ‘World Heart Day 2022’ – The Week

Merck Foundation in partnership with African First Ladies and Ministries of Health provided more than 720 scholarships of one-year Post-Graduate Diploma and two-year Master Degree in Preventative Cardiovascular Medicine, Diabetes and Endocrinology to doctors from 45 countries in Africa, Asia and beyond. These scholarships are included in the total 1450 scholarships Merck Foundation provided to doctors from 47 countries in 32 critical and underserved medical specialties such as oncology, fertility, respiratory medicine, acute medicine, orthopaedic and many more

Mumbai, Maharashtra, India&Nairobi, Kenya Business Wire India

Merck Foundation, the philanthropic arm of Merck KGaA Germany marks World Heart Day 2022 in partnership with African First Ladies, Ministries of Health, Medical Societies, and Academia, through their long-term commitment toward transforming patient care landscape and building health care capacity in Africa, Asia and beyond.

Senator, Dr. RashaKelej, CEO of Merck Foundation emphasized, Merck Foundation mark World Heart Day 2022 in a very unique way, that is by providing more than 720 scholarships of one-year Post-Graduate Diploma and two-year Master degree in Preventative Cardiovascular Medicine, Diabetes and Endocrinology to doctors from 45 countries. This will contribute to improving cardiovascular care in general since we focus on countries nationwide and not only the capitals. Moreover, I am also very proud that we have provided in total more than 1450 scholarships of one-year diploma and two-year master degree for doctors from 45 countries in 32 critical and underserved medical specialties such as; acute care, Pediatric Emergency, Advanced Surgery, Intensive care, Fertility, Embryology, Oncology, Respiratory and many more.

This is a great milestone to improve patient access to quality and equitable healthcare solutions across Africa and beyond. This achievement is the highlight of my career and my life.

So far, out of the 1450 scholarships, Merck Foundation has provided more than 120 scholarships for Cardiovascular care specialty training to young doctors from the following 23 countries: Burundi, Cambodia, Cameroon, Ghana, Indonesia, Kenya, Lesotho, Malaysia, Mauritius, Myanmar, Namibia, Nepal, Niger, Philippines, Rwanda, Sierra Leone, South Africa, Sri Lanka, Tanzania, UAE, Uganda, Zambia, and Zimbabwe.

Dr. Tatenda Hamilton Tengwana, Merck Foundation alumnus from Zimbabwe says, I always wanted to excel in my field and help patients suffering from heart diseases and other related issues and also help people to prevent heart disease if they are prone to it. I would like to thank Merck Foundation for making this dream a reality. I successfully completed my PG Diploma in Preventative Cardiovascular Medicine, the skills I gained from this program are tremendous and have helped me to gain confidence to treat cardiovascular patients in my country. I applaud Merck Foundation for supporting doctors like me who are eager to learn and serve their communities.

Moreover, Merck Foundation together with African First Ladies, has also introduced Awards for Media, Fashion Designers, Filmmakers, Musicians/ Singers, and new potential talents in these fields from African countries to Promote a healthy lifestyle and raise awareness about prevention and early detection of Diabetes and Hypertension. Details of the awards:

1. Merck Foundation Media Recognition Awards 2022 Diabetes & Hypertension:

Media representatives are invited to showcase their work through strong and influential messages to promote a healthy lifestyle raise awareness about prevention and early detection of Diabetes and Hypertension.

Submission deadline: 30th October 2022. Click here to view more details.

2. Merck Foundation Film Awards 2022 Diabetes & Hypertension: All African Filmmakers, Students of Film Making Training Institutions or Young Talents of Africa are invited to create and share a long or short FILMS, either drama, documentary or docudrama to deliver strong and influential messages to promote a healthy lifestyle raise awareness about prevention and early detection of Diabetes and Hypertension.

Submission deadline: 30th October 2022. Click here to view more details.

3. Merck Foundation Fashion Awards 2022 Diabetes & Hypertension: All African Fashion Students and Designers are invited to create and share designs to deliver strong and influential messages to promote a healthy lifestyle raise awareness about prevention and early detection of Diabetes and Hypertension.

Submission deadline: 30th October 2022. Click here to view more details.

4. Merck Foundation Song Awards 2022 Diabetes & Hypertension: All African Singers and Musical Artists are invited to create and share a SONG with the aim to promote a healthy lifestyle raise awareness about prevention and early detection of Diabetes and Hypertension.

Submission deadline: 30th October 2022. Click here to view more details.

Entries for all the awards are to be submitted via email to: submit@merck-foundation.com

Join the conversation on our social media platforms below and let your voice be heardFacebook: Merck FoundationTwitter: @MerckfoundationYouTube: MerckFoundationInstagram: Merck FoundationFlickr: Merck FoundationWebsite: http://www.merck-foundation.com

About Merck Foundation

The Merck Foundation, established in 2017, is the philanthropic arm of Merck KGaA Germany, aims to improve the health and wellbeing of people and advance their lives through science and technology. Our efforts are primarily focused on improving access to quality & equitable healthcare solutions in underserved communities, building healthcare and scientific research capacity and empowering people in STEM (Science, Technology, Engineering, and Mathematics) with a special focus on women and youth. All Merck Foundation press releases are distributed by e-mail at the same time they become available on the Merck Foundation Website. Please visit http://www.merck-foundation.com to read more. To know more, reach out to our social media: Merck Foundation; Facebook, Twitter, Instagram, YouTube and Flickr.

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Senator Dr. RashaKelej and Prof. Dr. Frank StangenbergHaverkamp with Merck Foundation Alumni

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Merck Foundation Together with African First Ladies Mark 'World Heart Day 2022' - The Week

Embryology

The LA Times gets abortion and the Church dramatically wrong – Angelus News

I dont think Ive ever come across an op-ed that was so obviously wrong but led with claims that are so obviously true.

Writing in the Los Angeles Times, a science writer and artist named Margaret Wertheim opens by noting that the reality of a pregnant woman does not fit into the system of categorization thats long been the de facto standard for Western culture.

This checks out.

She goes on to say that in modern Western philosophy, a person is conceived of as an entity with independent intellectual agency.

As the kids say today, facts.

But then things get weird. Wertheim insists that modern philosophers like Descartes who famously said, I think therefore I am were simply translating into secular terms the view of the Catholic Church. And this view is that human being-ness is predicated on an individual self with free will, and thus the capacity to distinguish between right and wrong.

She then does the math. In light of our post-Dobbs debate: the fetus which is described as a small bunch of cells, clearly doesnt have independent intellectual agency, free will, or the ability to distinguish between right and wrong. Abortion debate over, right?

The problem, Wertheim argues, is that pro-lifers who claim that the fetus is a person are going back to a medieval vision of the human person, one which the modern Western philosophical tradition reacted against.

But then things get even stranger. She moves to undermine her own argument by noting that the mother-fetus relationship stands outside Western obsessions with individuality and that a mother bearing a child is at once an individual and collective.

To be clear, the traditional Catholic view of the human person is that we are created as individuals-in-relationship, not only with our mother from the very moment we become a member of the Homo sapiens family (which every embryology textbook in the world teaches begins at fertilization) but with God, our family, other human beings, and all of creation. This anthropologic vision of radical relationship has at least 16 centuries of Christian Trinitarian thought behind it.

This is one reason feminist theologians have emphasized the analogy drawn between the bond of the pregnant woman with her baby and the intimacy of our relationship with God.

The fact of radical relationship, however, does not negate the individuality of those who are in such a relationship. This is one important difference between Christianity and eastern religions, which claim that individuality is an illusion.

The three persons of the Trinity are still individual persons. We are still individuals in our intimate relationship with a God we call Abba or Daddy. And the prenatal human remains an individual even as she has a nearly unimaginably intimate relationship with her mother.

Yes, they share an organ (the placenta); yes they exchange cellular tissue; yes, what the mother eats, drinks, smokes, and even speaks dramatically affects her baby. This is clearly a relationship unlike any other.

But the child is also an individual member of the species Homo sapiens. She has her own separate genetic code. She very often has a different blood type. She develops a four-chambered heart that pumps blood only six weeks after fertilization. If a hormone isnt released during pregnancy, the mothers immune system will attack the prenatal child as an individual separate and different from the mother.

So a Catholic understanding far from suffering from its pre-modern view of the human person is able to account for both the individuality and radical relationship involved in pregnancy precisely because its view of the human person comes out of its ancient and medieval reflections on the Trinity. Reflections that are not beholden to the idea that a human being is a thinking thing with free will. Indeed, those capacities dont develop until well after birth.

Anyone who wants to totally subsume those involved in the radical relationship of pregnancy as nonpersons are missing something essential about the relationship: both mother and baby exist as individuals and both have a right to life. This is one reason why pro-lifers need to do a much better job explaining (in the face of often cynical attempts to suggest otherwise) that in life-threatening situations, medical intervention to save the mothers life is the top priority.

But it also means that any polity that makes the prenatal child with a beating heart into a nonperson is participating in what Pope Francis calls throwaway culture. People use dishonest language like small bunch of cells to ignore or distract from the individuality of the child in order to make her easier to discard as a being who simply doesnt have a moral status.

As pro-life feminists have pointed out for decades, the fact that throwaway culture used to do this to women indicates that the ideology behind abortion rights has merely redistributed the oppression to another class of human beings.

Happily, a Catholic vision of the human person stands ready to honor both the individuality of the mother and baby as well as their radical relationship by working for prenatal justice, saving the life of her mother, and insisting that the broader community support their familial relationship with substantial resources.

Is it such a shame that the Church, which catechized Wertheim as a child, apparently didnt pass this wonderful vision of the human person on to her. If we had, she would have written a very different op-ed, one that honors the full individuality of mother and child in the midst of a beautifully radical relationship.

See the rest here:
The LA Times gets abortion and the Church dramatically wrong - Angelus News

Genetics

Stroke genetics informs drug discovery and risk prediction across ancestries – Nature.com

Bordeaux Population Health Research Center, University of Bordeaux, Inserm, UMR 1219, Bordeaux, France

Aniket Mishra,Quentin Le Grand,Ilana Caro,Constance Bordes,David-Alexandre Trgout,Marine Germain,Christophe Tzourio,Jean-Franois Dartigues,Sara Kaffashian,Quentin Le Grand,Florence Saillour-Glenisson&Stephanie Debette

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany

Rainer Malik,Marios K. Georgakis,Steffen Tiedt&Martin Dichgans

Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Iwate, Japan

Tsuyoshi Hachiya,Makoto Sasaki,Atsushi Shimizu,Yoichi Sutoh,Kozo Tanno&Kenji Sobue

Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

Tuuli Jrgenson,Kristi Krebs,Kaido Lepik,Tnu Esko,Andres Metspalu,Reedik Mgi,Mari Nelis&Lili Milani

Institute of Mathematics and Statistics, University of Tartu, Tartu, Estonia

Tuuli Jrgenson

Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan

Shinichi Namba,Takahiro Konuma&Yukinori Okada

Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA

Daniel C. Posner,Kelly Cho,Yuk-Lam Ho&Jennifer E. Huffman

TIMI Study Group, Boston, MA, USA

Frederick K. Kamanu,Nicholas A. Marston,Marc S. Sabatine&Christian T. Ruff

Division of Cardiovascular Medicine, Brigham and Womens Hospital, Harvard Medical School, Boston, MA, USA

Frederick K. Kamanu,Nicholas A. Marston,Marc S. Sabatine&Christian T. Ruff

Division of Molecular Pathology, Institute of Medical Sciences, The University of Tokyo, Tokyo, Japan

Masaru Koido,Takayuki Morisaki&Yoishinori Murakami

Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan

Masaru Koido,Mingyang Shi,Yunye He&Yoichiro Kamatani

Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA

Marios K. Georgakis,Livia Parodi,Jonathan Rosand,Christopher D. Anderson,Ernst Mayerhofer&Christopher D. Anderson

Program in Medical and Population Genetics, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA

Marios K. Georgakis,Livia Parodi,Phil L. de Jager,Jonathan Rosand,Christopher D. Anderson,Guido J. Falcone,Phil L. de Jager,Ernst Mayerhofer&Christopher D. Anderson

Laboratory of Clinical Genome Sequencing, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan

Yi-Ching Liaw&Koichi Matsuda

Department of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung, Taiwan

Yi-Ching Liaw,Pei-Hsin Chen&Yung-Po Liaw

Department of Internal Medicine, University of Turku, Turku, Finland

Felix C. Vaura&Teemu J. Niiranen

Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Turku, Finland

Felix C. Vaura&Teemu J. Niiranen

Nuffield Department of Population Health, University of Oxford, Oxford, UK

Kuang Lin,Zhengming Chen,Cornelia M. van Duijn,Robert Clarke,Rory Collins,Richard Peto,Yiping Chen,Zammy Fairhurst-Hunter,Michael Hill,Alfred Pozarickij,Dan Schmidt,Becky Stevens,Iain Turnbull,Iona Y. Millwood,Keum Ji Jung&Robin G. Walters

Department of Research and Innovation, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway

Bendik Slagsvold Winsvold,Ingrid Heuch,Linda M. Pedersen,Amy E. Martinsen,Espen S. Kristoffersen&John-Anker Zwart

K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway

Bendik Slagsvold Winsvold,Sigrid Brte,Kristian Hveem,Ben M. Brumpton,Jonas B. Nielsen,Maiken E. Gabrielsen,Anne H. Skogholt,Ben M. Brumpton,Maiken E. Gabrielsen,Amy E. Martinsen,Jonas B. Nielsen,Kristian Hveem,Laurent F. Thomas&John-Anker Zwart

Department of Neurology, Oslo University Hospital, Oslo, Norway

Bendik Slagsvold Winsvold&Anne H. Aamodt

Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA

Vinodh Srinivasasainagendra,Hemant K. Tiwari&George Howard

Department of Neurology and Cerebrovascular Disease Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea

Hee-Joon Bae

Rajendra Institute of Medical Sciences, Ranchi, India

Ganesh Chauhan,Amit Kumar&Kameshwar Prasad

Thrombosis and Atherosclerosis Research Institute, David Braley Cardiac, Vascular and Stroke Research Institute, Hamilton, Ontario, Canada

Michael R. Chong&Guillaume Par

Department of Pathology and Molecular Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada

Michael R. Chong&Guillaume Par

Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland

Liisa Tomppo,Jukka Putaala,Gerli Sibolt,Nicolas Martinez-Majander,Sami Curtze,Marjaana Tiainen,Janne Kinnunen&Daniel Strbian

Center for Genomic and Precision Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria

Rufus Akinyemi,Abiodun M. Adeoye&Mayowa O. Owolabi

Neuroscience and Ageing Research Unit Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria

Rufus Akinyemi

Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands

Gennady V. Roshchupkin,Maria J. Knol,Cornelia M. van Duijn,Najaf Amin,Sven J. van der Lee,Mohsen Ghanbari,Mohammad K. Ikram&Mohammad A. Ikram

Department of Radiology and Nuclear Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands

Gennady V. Roshchupkin

The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel

Naomi Habib&Anael Cain

Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA

Yon Ho Jee

Department of Clinical Biochemistry, Copenhagen University HospitalRigshospitalet, Copenhagen, Denmark

Jesper Qvist Thomassen,Anne Tybjrg-Hansen,Marianne Benn&Ruth Frikke-Schmidt

Department of Molecular and Functional Genomics, Weis Center for Research, Geisinger Health System, Danville, VA, USA

Vida Abedi&Jiang Li

Department of Public Health Sciences, College of Medicine, The Pennsylvania State University, State College, PA, USA

Vida Abedi

Stroke Pharmacogenomics and Genetics Laboratory, Biomedical Research Institute Sant Pau (IIB Sant Pau), Barcelona, Spain

Jara Crcel-Mrquez,Nuria P. Torres-Aguila,Natalia Cullell,Elena Muio,Cristina Gallego-Fabrega,Miquel Lleds,Laia Lluci-Carol&Israel Fernndez-Cadenas

Departament de Medicina, Universitat Autnoma de Barcelona, Barcelona, Spain

Jara Crcel-Mrquez

The Danish Twin Registry, Department of Public Health, University of Southern Denmark, Odense, Denmark

Marianne Nygaard&Kaare Christensen

Department of Clinical Genetics, Odense University Hospital, Odense, Denmark

Marianne Nygaard&Kaare Christensen

Center for Alzheimers and Related Dementias, National Institutes of Health, Bethesda, MD, USA

Hampton L. Leonard&Mike A. Nalls

Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA

Hampton L. Leonard&Mike A. Nalls

Data Tecnica International, Glen Echo, MD, USA

Hampton L. Leonard&Mike A. Nalls

Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA

Chaojie Yang,Ani Manichaikul,Stephen S. Rich,Wei Min Chen,Michle M. Sale&Wei-Min Chen

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA, USA

Chaojie Yang

British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK

Ekaterina Yonova-Doing,Michael Inouye&Joanna M. M. Howson

Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK

Ekaterina Yonova-Doing&Joanna M. M. Howson

Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA

Adam J. Lewis,Jing He,Seung Hoan Choi&Lisa Bastarache

Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA

Renae L. Judy

Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

Tetsuro Ago&Takanari Kitazono

Original post:
Stroke genetics informs drug discovery and risk prediction across ancestries - Nature.com