Dr. Lisak honored with Healthcare Professional Champion Award for efforts against MS – The South End

Wayne State University School of Medicine Professor of Neurology Robert Lisak, M.D., FRCP, FAAN, received the Healthcare Professional Champion Award from the Michigan Chapter of the National Multiple Sclerosis Society.

The award is presented to an individual who has demonstrated their commitment to helping people meet the challenges of Multiple Sclerosis, including improving access to and quality of MS clinical care. Recipients must have demonstrated leadership in establishing relationships with other health care providers and professional organizations, increasing referrals to the society and improving MS knowledge in the health care workforce.

It is nice to be recognized for doing things that you enjoy doing for others, said Dr. Lisak, who received the honor Jan. 11 at the chapters annual Breakthroughs in MS meeting in Novi. Mich.

Mirela Cerghet, M.D., Ph.D., a neurologist with the Henry Ford Health System, presented Dr. Lisak, also a professor of Biochemistry, Microbiology and Immunology, and former chair of WSU Neurology, with the award on behalf of the chapter.

Dr. Lisak, said Dr. Cerghet, has been a champion for patients living with MS for the entire span of his distinguished career. His involvement with the National MS Society spans decades, and over the years of his service great strides have been made toward creating a world free of MS, including the development of all the disease-modifying medications.

A member of the societys Board of Trustees and chair of the Healthcare Provider Council, Dr. Lisak has played a critical role in attracting new talent to the field through his involvement in MS professional education, medical student mentoring, clinical training programs and engagement with clinical fellows, Dr. Cerghet said.

Most recently, Dr. Lisak, representing both WSU and the Consortium of Multiple Sclerosis Centers in his role on the AAN Guideline Development, Dissemination and Implementation Subcommittee, helped develop new guidelines for disease-modifying therapy for multiple sclerosis. The Consortium of Multiple Sclerosis Centers is a professional organization of MS centers and health care providers and researchers in the United States and Canada committed to a comprehensive multidisciplinary approach to treatment and care, education and research and advocacy for MS so that the centers can provide the best care and outcomes for patients and their families. The consortium also is an international clearinghouse for research results, the latest treatments, clinical trials and patient education programs.

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Dr. Lisak honored with Healthcare Professional Champion Award for efforts against MS - The South End

January: smoking cessation | News – University of Bristol

As smokers know all too well, nicotine is highly addictive. Its hard to quit smoking, a habit that claims the lives of more than seven million people each year.

Smoking tobacco delivers nicotine to the neuroreceptors responsible for addiction, affecting the nervous system and causing addiction.

A new study, led by scientists from the University of Bristol, into the molecular interactions involved has revealed how these neuroreceptors respond to nicotine.

The researchers used new computational simulation methods to discover how receptors in the brain respond to nicotine.

One of the key features of the study is the speed at which the discovery was made, thanks to the use of Oracle Cloud Infrastructure, which allowed the researchers to run a large number of simulations in unprecedentedly short time.

The work brought together computational chemists, biochemists and research software engineers, working together to deploy large numbers of simulations of nicotine receptors in the cloud.

Reducing the time to results to just five days using Oracles high-performance cloud infrastructure is transformational from a research perspective. Calculations that might otherwise have taken months to complete were completed in a matter of days.

The study, carried out by researchers from Bristol in partnership with Oracle, whose cloud technologies were a key part of the investigation, is reported in the Journal of the American Chemical Society, the flagship publication of the American Chemical Society, the worlds largest scientific society and a global leader in providing access to chemistry-related research. The project was supported by funding from EPSRC.

Co-author of the study, Professor Adrian Mulholland, from Bristols Centre for Computational Chemistry, part of Bristols School of Chemistry, said: Nicotine is highly addictive: its very hard to give up smoking. To understand why it is so addictive, and to make molecules to help people quit, we need to understand how it affects the nervous system.

We have used simulations to model and understand how nicotine affects receptors in the brain. Using the power of cloud computing, we were able to show how nicotine exerts its effects, at the molecular level, the first stage of signaling in the brain. This information, and the methods we have developing, will help in developing new smoking cessation aids.

Researchers are now working with Achieve Life Sciences to design and develop molecules that mimic nicotine, and computer simulations that will help test their potential effectiveness. This work builds on previous studies using chemical synthetic approaches to develop new smoking cessation aids, which will be investigated and tested in simulation scenarios.

Smoking is the second most common cause of death worldwide, but most current anti-smoking drugs are only moderately effective in reducing symptoms of withdrawal and may cause undesirable side effects. New, specific and effective smoking cessation aids are needed.

Nicotine is the major psychoactive agent in tobacco and causes addiction by binding to specific receptors in the brain. Understanding how nicotine binds to these receptors and creates the nicotine hit and subsequent craving is a key focus for public health research.

The study saw researchers perform 450 individual molecular dynamics simulations of the biochemistry associated with the binding of nicotine to a subtype (7) of nicotinic acetylcholine receptors in the brain. They were able to compare with other types nicotine receptor and identify common features of receptor activation.

The study also showed how cloud computing can be combined effectively with more traditional high-performance computing.

This work shows how rigorous simulations can be used to predict effects on drug targets in a matter of days.

On this quick timescale, calculations help to plan and interpret experiments, and will help design and develop effective drugs. More broadly, the agility and other benefits of using cloud computing for research offers the potential to accelerate the pace of discovery dramatically.

Paper:

A general mechanism for signal propagation in the nicotinic acetylcholine receptor family by A. Oliveria, C. Edsall, C. Woods, P. Bates, G. Viedma-Nunez, S. Wonnacott, I. Bermudez, G. Ciccotti, T. Gallagher, R. Sessions and A. Mulholland in Journal of the American Chemical Society

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January: smoking cessation | News - University of Bristol

An Astrobiologist Seeks to Explain Whether There Are Other ‘Beings’ Amongst Us – Qrius

Samantha Rolfe, University of Hertfordshire

Life is pretty easy to recognise. It moves, it grows, it eats, it excretes, it reproduces. Simple. In biology, researchers often use the acronym MRSGREN to describe it. It stands for movement, respiration, sensitivity, growth, reproduction, excretion and nutrition.

But Helen Sharman, Britains first astronaut and a chemist at Imperial College London, recently said that alien lifeforms that are impossible to spot may be living among us. How could that be possible?

While life may be easy to recognise, its actually notoriously difficult to define and has had scientists and philosophers in debate for centuries if not millennia. For example, a 3D printer can reproduce itself, but we wouldnt call it alive. On the other hand, a mule is famously sterile, but we would never say it doesnt live.

As nobody can agree, there are more than 100 definitions of what life is. An alternative (but imperfect) approach is describing life as a self-sustaining chemical system capable of Darwinian evolution, which works for many cases we want to describe.

The lack of definition is a huge problem when it comes to searching for life in space. Not being able to define life other than well know it when we see it means we are truly limiting ourselves to geocentric, possibly even anthropocentric, ideas of what life looks like. When we think about aliens, we often picture a humanoid creature. But the intelligent life we are searching for doesnt have to be humanoid.

Sharman says she believes aliens exist and theres no two ways about it. Furthermore, she wonders: Will they be like you and me, made up of carbon and nitrogen? Maybe not. Its possible theyre here right now and we simply cant see them.

Such life would exist in a shadow biosphere. By that, I dont mean a ghost realm, but undiscovered creatures probably with a different biochemistry. This means we cant study or even notice them because they are outside of our comprehension. Assuming it exists, such a shadow biosphere would probably be microscopic.

So why havent we found it? We have limited ways of studying the microscopic world as only a small percentage of microbes can be cultured in a lab. This may mean that there could indeed be many lifeforms we havent yet spotted. We do now have the ability to sequence the DNA of unculturable strains of microbes, but this can only detect life as we know it that contain DNA.

If we find such a biosphere, however, it is unclear whether we should call it alien. That depends on whether we mean of extraterrestrial origin or simply unfamiliar.

A popular suggestion for an alternative biochemistry is one based on silicon rather than carbon. It makes sense, even from a geocentric point of view. Around 90% of the Earth is made up of silicon, iron, magnesium and oxygen, which means theres lots to go around for building potential life.

Silicon is similar to carbon, it has four electrons available for creating bonds with other atoms. But silicon is heavier, with 14 protons (protons make up the atomic nucleus with neutrons) compared to the six in the carbon nucleus. While carbon can create strong double and triple bonds to form long chains useful for many functions, such as building cell walls, it is much harder for silicon. It struggles to create strong bonds, so long-chain molecules are much less stable.

Whats more, common silicon compounds, such as silicon dioxide (or silica), are generally solid at terrestrial temperatures and insoluble in water. Compare this to highly soluble carbon dioxide, for example, and we see that carbon is more flexible and provides many more molecular possibilities.

Life on Earth is fundamentally different from the bulk composition of the Earth. Another argument against a silicon-based shadow biosphere is that too much silicon is locked up in rocks. In fact, the chemical composition of life on Earth has an approximate correlation with the chemical composition of the sun, with 98% of atoms in biology consisting of hydrogen, oxygen and carbon. So if there were viable silicon lifeforms here, they may have evolved elsewhere.

That said, there are arguments in favour of silicon-based life on Earth. Nature is adaptable. A few years ago, scientists at Caltech managed to breed a bacterial protein that created bonds with silicon essentially bringing silicon to life. So even though silicon is inflexible compared with carbon, it could perhaps find ways to assemble into living organisms, potentially including carbon.

And when it comes to other places in space, such as Saturns moon Titan or planets orbiting other stars, we certainly cant rule out the possibility of silicon-based life.

To find it, we have to somehow think outside of the terrestrial biology box and figure out ways of recognising lifeforms that are fundamentally different from the carbon-based form. There are plenty of experiments testing out these alternative biochemistries, such as the one from Caltech.

Regardless of the belief held by many that life exists elsewhere in the universe, we have no evidence for that. So it is important to consider all life as precious, no matter its size, quantity or location. The Earth supports the only known life in the universe. So no matter what form life elsewhere in the solar system or universe may take, we have to make sure we protect it from harmful contamination whether it is terrestrial life or alien lifeforms.

So could aliens be among us? I dont believe that we have been visited by a life form with the technology to travel across the vast distances of space. But we do have evidence for life-forming, carbon-based molecules having arrived on Earth on meteorites, so the evidence certainly doesnt rule out the same possibility for more unfamiliar life forms.

Samantha Rolfe, Lecturer in Astrobiology and Principal Technical Officer at Bayfordbury Observatory, University of Hertfordshire

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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The Anatomy of a Lubricant – AgWeb

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Anatomy of a 3-3 home stand: numbers were average, like the results – The Official Home of the Dallas Mavericks – Mavs.com

To steal a line from the commercials about Las Vegas, the Mavericks and their fans certainly hope what happens at American Airlines Center stays at American Airlines Center.

They really dont want it following them on the road.

Their six-game home stand longest of the season is history and the Mavericks ended with a pedestrian 3-3 record. It just doesnt get more average than that.

So how did they get there? Its not rocket science.

The numbers clearly showed that the Mavericks didnt deserve anything better than what they got during their 11-day stay at AAC. Here, well take a closer look.

First, the good news: The Mavericks averaged 115 points per game and only gave up 111.8 during the six games. Pretty much all of that differential can be traced to the 18-point win over Philadelphia in the finale of the home stand.

Beyond that, the numbers scream out that the Mavericks were utterly average on the home stand.

Rebounding: The Mavericks averaged 44.8 rebounds per game. Their opponents averaged 45.3 boards. That doesnt sound like much, but for a team that has by and large been good at retrieving missed shots most of the season, it wasnt good enough.

Defense: They only forced 9.8 turnovers per game on the home stand. Thats a ridiculously low number. Thats also part of the reason why opponents averaged 91 field-goal attempts per game to 87.5 for the Mavericks. Anyway you slice it, thats 3.5 more chances to score points for the other team. Opponents also were basically even at the free-throw line with the Mavericks.

Free-throw shooting. The Mavericks were 72.3 percent from the line. They shot more free throws than their six opponents, but made less. Thats a lot of free points left on the table.

When you add it up, it was a .500-worthy effort on the home stand.

On the bright side, the Mavericks at least finished it with a solid win against Philadelphia. That creates a smidge of momentum that they can take with them to Golden State on Tuesday and Sacramento on Wednesday.

The Mavericks were about as good as theyve been all season in a 68-41 second half against the Sixers.

When our guys with that kind of force, our crowd is a different kind of crowd, coach Rick Carlisle said. We got great fans, but when we play with this kind of force, our fans take it to another level and it makes it a lot harder on opponents.

And, considering Kristaps Porzingis did not play on the home stand (its possible, Carlisle said, he could return on the road trip), the Mavericks at the least were able to tread water.

Real proud of the guys for hanging in, Carlisle said. This has been a very difficult, challenging stretch for a lot of reasons the frequency of the games, the level of the opponents, some of the losses have been very close and difficult. And after last night, its easy to get down. But guys hung in.

The Mavericks have been better on the road all season than theyve been at AAC. With nine of their next 11 games on the road, they hope they can make a charge during the upcoming stretch.

Twitter: @ESefko

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Anatomy of a 3-3 home stand: numbers were average, like the results - The Official Home of the Dallas Mavericks - Mavs.com

The anatomy of a crazy finish: One hole, three groups, nine players, squeegees, drops, three-putts and more – Golf.com

Brendan Steele missed the green on the par-3 17th and made a bogey, which cut his Sony Open lead to just one with one to play. Forty minutes later(!) he finished the 18th hole and dashed off for a sudden-death playoff with Cameron Smith. But what happened in those 40-some minutes in between? Well, a little bit of everything.

It was a wet and soggy day at Waialae Country Club in Honolulu, Hawaii, but there were still a handful of players in contention when they reached the par-5 18th on Sunday. An eagle was in play on 18, and with final-round nerves ready to bite at any moment, so were bogeys. Heres how it all went down.

Mark Anderson, Sungjae Im and Bo Hoag, the third-to-last threesome of the day, were on the 18th green and trying to finish up their rounds. As they waited for grounds crew workers to squeegee water off the green, Webb Simpson, Collin Morikawa and Ryan Palmer stood in the fairway and rough. A couple hundred yards behind them stood Steele, Smith and Kevin Kisner, waiting on the tee, in silence, stationed under massive umbrellas. The rain was pouring. The wait continued.

No one in the third-to-last group was in contention to win, but Hoag was looking to lock up a key top 10, which he did. Once that group cleared, it was go time. Morikawa didnt have a chance to win anymore, but Simpson and Palmer were both at 10 under, one behind Steele. Smith, waiting back on the tee, was also at 10 under and one back.

Simpson, from the wet rough, was up first and hit a low burner that rolled into the fairway, which gave way to Palmers heroic effort from the fairway bunker. The Texan had 261 to the front edge of the green but blocked it way right. It ricocheted off the top of metal scaffolding on a TV screen, and the search for his ball was on.

Yeah, [the wait] wasnt helpful, Steele said. Stood on the tee for a long time, which was OK because I was kind of collecting myself from 17. I was watching Ryan and trying to figure out what he was doing. I was trying to figure out where he could have possibly hit it, and then I was thinking, Oh, hes hit it out of bounds right. I was like, Well, we dont want to do that. So that wasnt positive at all.

Finally, the last threesome was ready from the tee, although the wait ended up being more than 15 minutes. All three players found the fairway and walked ahead, but then came another lengthy delay. Palmers ball wasnt found, so after the three-minute search concluded, PGA Tour rules official Mark Russell told Palmer that rules official Slugger White would take him back to drop.

I told Slugger driving up, I was trying to hit the left side of the cylinders holding up the scoreboard, not the right side, Palmer joked.

The wait continued for Steele and Co.:

Next was Simpson, who had to wave off more grounds crew staffers who were again marching up and down the green with squeegees. He wedged it to 15 feet and had that left for birdie. Next came Palmer, who dropped from the bunker and knocked it just short of the green. He nearly chipped in for par but settled for a bogey and bowed out of the race for the win.

Simpson lined up his birdie putt that would have tied him for the lead, but he barely missed it out to the left. But just when you thought that was it from this group, it wasnt! Morikawa waltzed up to his ball to clean up from 4 feet for birdie, but he missed and then he missed again from 2 feet. It was a rough three-putt to finish for the up-and-comer, who played the last four in three over.

Back in the fairway, with the green finally clear, another 15 minutes had passed since Steele-Smith-Kisner hit their tee shots. Did the nerves get to Steele? Maybe.

The 36-year-old had 245 yards to the hole but hooked it well left, and it ricocheted off the grandstands and came to rest near a galley rope on the 10th fairway.

This is almost in the next area code, said analyst Paul Azinger, who also used his telestrator to draw this handy circle where Steeles ball landed:

Luckily for Steele, he received a free drop due to a temporary immovable obstruction and had about 75 yards left to the pin. He dropped between a tent and the gallery and after a car alarm went off, of course pitched on to about 28 feet.

Although Steele lucked out with his drop, his wayward second shot proved costly. He two-putted for par, but Smith got up-and-down from a bunker to make birdie and force a playoff. The extra hole, the par-4 10th, wasnt as climactic as the 18th, as Smith, the last man standing, two-putted for par to win.

I just had to hang in there, Smith said. No one was playing good golf today seemed like. Conditions got a lot easier at the end there, but just hung in there, and what do you know.

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The anatomy of a crazy finish: One hole, three groups, nine players, squeegees, drops, three-putts and more - Golf.com

10 Things To Expect At Your 20 Week Anatomy Scan | BabyGaga – BabyGaga

Hitting the 20-week mark of pregnancy is a major accomplishment. Youre halfway there to meeting your little one!

What also typically happens around 20 weeks? You get to go to your anatomy scan, also known as a level 2 ultrasound. This is where you get to see your baby in-depth and how much he or she has grown. At this point in your pregnancy, youve probably only had one, maybe two sonograms, so youre probably dying to see how everything is progressing.

Not sure what to expect at your anatomy scan? Here are 10 things to keep in mind before heading to your appointment:

RELATED: 10 Things To Know About Getting An Ultrasound

An ultrasound technician will look closely at every single internal part of your babys body, including the four chambers of the heart, the kidneys, the bladder, brain, spine and more, as well as all the external areasthose cute tiny fingers, toes, legs, arms, and even the little rump.

To ensure theyre getting the perfect view, the technician will twist and turn the ultrasound wand all over your belly, controlling the images on screen. While they will likely be explaining what each part is showing up on the screen, feel free to ask questions so you fully understand everything youre viewing. Its quite the show!

If you didnt find out the gender of your baby during a noninvasive prenatal test in the first trimester, then the moment of truth awaits: Is your baby a boy or a girl? This can be an incredibly exciting moment for both you and your spouse, especially if youve had intense gut feelings over which one it could be. Note that depending on what position your baby is in, it could be tougher to determine.

If you dont want to find out the gender until birth, thats okay toojust let your technician know and shell have you look away when shes examining the sex organs.

Did you know the placenta can implant itself in different positions in your body? For example, if youre not feeling flutters or kicks just yet, you may learn you have an anterior placenta or a placenta that grows in the front of the uterus.

RELATED: 10 Things To Know About Your 8-Week Ultrasound

You could also have a posterior placenta, which is located at the back of the uterus; a fundal placenta, located at the top of the uterus; a low-lying placenta, which is at the bottom of the uterus; or having your placenta simply be on the side of the uterus. Luckily, where the placenta is located doesnt typically affect pregnancy or delivery, but speak with your doctor if you have any concerns.

Whether youve put on one or 10 pounds in your pregnancy so far, you might be curious to know just what your actual baby weighs these days. Around the 20-week mark, a normal range is around a whopping 8-13 ounces. But dont be alarmed if youre measuring ahead or behindthis is, of course, just an estimate!

The technician will also measure the baby from crown to rump, as well as its middle section and around the head. He or she still has a lot more growing to do,but will likely have a few growth spurts coming up, so be prepared!

While you may be quickly in and out at your other doctors appointment, youll need to set aside at least 30-45 minutes for your anatomy scan. Sometimes it can take upwards of an hour, especially if your baby is squirming around and not showing the technician what needs to be seen.

RELATED:10 Things to Do During Nap Time (Besides Nap)

Most of the time, changing positions on the table or having the technician wiggle around the wand can get the baby to move, but if theyre not able to get the detailed photos they need, you may need to come back. This doesn't mean anything is wrong, so take it as a positive thing: Just another chance to see your baby!

At your last ultrasound, you may have gotten just three or four photos of your babyand the fetuswas likely just the size of a gummy bear. This time, youll get to take home at least a dozen or more photos of various parts of your baby (which are much more developed than last time).

Note that this ultrasound may be the last time you see the baby before its born, so really take in these photos. Get some cute frames to put one or two of the photos in, or displaythem on your fridge so you can see him or her every time you grab a snack.

Most anatomy scans offer standard 2-dimensional images, but more and more offices are converting to 3D or even 4D ultrasound technology. It doesnt hurt to ask if this is something your practice offers.If they dont, you can always find a place that offers private ultrasoundsyou may just need to pay a little extra for it.

RELATED: 10 Things About Ultrasounds You Didn't Know (And Should)

If youre curious about what your baby looks like, seeing him or her in 3D or 4D can really give you a clue if theyre taking more after mom or dad. So long as the baby is in a good position, youll get a solid glance at more of their features.

Seeing your baby on-screen during your anatomy scan can really put things into perspective about what he or she is doing in there. It may be pretty surprising to see just how much theyre moving around!

If youve got an especially wiggly baby, youll see it all come up on the screen. They could be doing anything from sprawling out their legs to putting their hands over their head to even sucking their thumb. No matter what position theyre in, its truly mesmerizing to watch (and this is only the beginning!).

It can be truly surreal to see your baby right there on the screenin front of you, especially as the first time youre seeingthem starting to look like a real human! Its true that you never realize just how cute baby feet and toes are until you see them in black and white on your own child.

Every single body part the technician scans over will make you squeal with delight, wondering how in the world this nearly fully developed human is growing inside of you. If you didnt think childbearing was a miracle before, you surely will now!

Even though the anatomy scan is an exciting time, you might be surprised that youre a bit nervous before heading in. This is totally normal (after all, youre a mom now and the worrying never ends).

Its easy to be scared that the technician is going to find something wrong, butremember that its better to be prepared in advance. If you end up getting referred to a specialist, you can get likely get whatever the problem is under control and prepare for whats to come. But chances are, youll come away from the anatomy scan relieved and happy.

NEXT:10 Joyous Pregnancy Moments You Didn't Expect When You Became Pregnant

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2020 is full of 4-H opportunities for youth – Salisbury Post – Salisbury Post

By Laura Allen

Rowan County 4-H Agent

Happy New Year! 4-H enrollment begins annually in January of each year, so now is a great time to join Rowan County 4-H.

4-H offers a broad range of opportunities for youth ages 5-18 (as of Jan. 1). Through 4-H, youth explore their interests and participate in leadership and citizenship development opportunities offered at the local, district, state and/or national levels. 4-H provides a positive environment for youth to learn by doing, while having guidance from adult mentors.

There are lots of 4-H events coming up soon that will be great opportunities for the youth in your life. I challenge you to find a way to get involved with 4-H in 2020.

Speak-Up

The Speak-Up workshop series focuses on developing public speaking skills in youth. There are four workshops: Jan. 27, Feb. 3, 10 and 17. Session 1 is for youth ages 7-11 as of Jan. 1 and is from 4:30-5:45 p.m. Session 2 is for youth ages 12-18 as of Jan. 1 and is from 6-7:15 p.m.. Total cost is $40 per child (covers all four workshops).

Participants must pre-register by Jan. 17. A limit of 10 youth per session. Workshop leader is Cheryl Kane of Barton & Kane Consolidated who has years of experience with public speaking and leadership development. Workshops are held at Rowan County Cooperative Extension.

Embryology

This school enrichment program is open to second-grade and seventh-grade classrooms within public, private and charter schools in Rowan County, as well as home-school families.

Teachers will be trained and provided with an incubator, fertilized eggs and curriculum/materials to allow their students to have a hands-on opportunity to learn about the life cycle of chicks. Those who participate will have to supply a tote/box to use as a brooder box, shavings and heat lamp. The cost is $10 per classroom. Supplies are limited to 30 participants per cycle listed below. Pre-registration is required. Those interested can register by emailing laura_allen@ncsu.edu. The embryology cycles offered this year are:

Private/Charter/Home-School Cycle: Feb. 4 at 3:30 p.m. (training and pick up); Feb. 28 (return chicks and materials by 4:30 p.m.); must pre-register by Jan. 17.

Public School Cycle 1: March 3 at 3:30 p.m. (training and pick up); March 27 (return chicks and materials by 4:30 p.m.); must pre-register by Feb. 7.

Public School Cycle 2: April 14 at 3:30 p.m. (training and pick up); May 8 (return chicks and materials by 4:30 p.m.); must pre-register by Feb. 7.

4-H Clubs

Rowan County has nine 4-H clubs. We have two clubs that focus on a variety of topics. The additional clubs have more focused topics and include a cooking club, a livestock club and a plant/nature homeschool club, two horse clubs and two shooting sports clubs.

These clubs are made up of at least one approved adult volunteer and youth who join the club. The clubs allow youth to learn how to run a business meeting and provide additional educational opportunities for youth. Youth in these clubs are involved in the total 4-H program and participate in 4-H achievement plans, project record books, presentations and other opportunities and competitions offered through 4-H.

Clubs meet at least once per month. Any youth ages 5-18 as of Jan. 1 can join and new adult volunteers are welcome, too. There is also the opportunity to start a new 4-H club, if you desire.

4-H Camp

Rowan County 4-H will be attending 4-H Camp at Betsy-Jeff Penn 4-H Educational Center in Reidsville June 28-July 3. The camping facility offers lots of opportunities for youth to learn new skills and make new friends. Activities include high ropes courses, rock climbing, arts and crafts, cooking, horses, archery, nature exploration, campfires, canoeing, swimming, team building and more.

4-H Camp is accredited through the American Camp Association. Total cost for youth is $420. Any Rowan County youth can attend, regardless if they are in 4-H. Active Rowan County 4-Hers are offered a discounted price. Scholarship opportunities may be available.

We are also seeking any donations from local citizens or companies to help offset costs for youths who need financial assistance. To attend, a $150 non-refundable deposit and registration form are due to Rowan County 4-H by March 25. The remaining balance is due by June 2.

Competitions

4-H provides competitions in the following areas: presentations, project record books, expressive arts, photography, horse shows, dairy/poultry/livestock/horse judging and quiz bowl, shooting sports and more. Youth have many opportunities to learn and practice their skills.

If you/your children are interested in any of these opportunities, please email 4-H Agent Laura Allen at laura_allen@ncsu.edu or call 704-216-8970. You can also check out the most recent Rowan County 4-H newsletter at https://rowan.ces.ncsu.edu/wp-content/uploads/sites/9/2020/01/January-4-H-Newsletter.pdf?fwd=no.

Rowan County Cooperative Extension is located at 2727-A Old Concord Road Salisbury, NC 28146.

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2020 is full of 4-H opportunities for youth - Salisbury Post - Salisbury Post

Behavioral Economics Latest Bias: Seeing Bias Wherever It Looks – Yahoo Finance

(Bloomberg) -- Behavioral economics, it seems, might just have a bias problem of its own.

Once dismissed as little more than psychobabble, the discipline, which marries classical economics with psychology, has won widespread acclaim over the past decade. Its left an indelible mark on business, finance and policy making by explaining all the mind-bending ways people, try as they might, dont act rationally. Along with the Nobel Prizes, its become a bona fide cultural phenomenon. Best sellers like Daniel Kahnemans Thinking, Fast and Slow, countless TED talks and even a cameo turn by one of its founders in the blockbuster movie The Big Short.

Yet for a small, but vocal group of skeptics, the field has quickly become a victim of its own astounding success. Call it the bias bias.

Drawing on the work of longtime critic Gerd Gigerenzer, an expert in psychology at the Max Planck Institute for Human Development, they point to the tendency of those who have embraced its ideas to see biases everywhere -- even when there are none. Not only do they bemoan the cottage industry of pseudoscience thats cropped up around behavioral economics, but they also see some deep, fundamental flaws with its approach.

Non-specialists appropriating the language of behavioral economics is a little like a poor mans way of saying, Hey, Im smart, said Emanuel Derman, a professor of financial engineering at Columbia University. The public loves it, but I dont think its worth very much.

While examples like the hot-hand fallacy in sports and the Dunning-Kruger effect (where people who dont know a lot about something literally dont know that they dont know) have helped change the way we think we understand human behavior, its not hard to see how things could have gotten out of hand.

A Wikipedia entry for cognitive biases currently lists nearly 200 entries. They range from the actor-observer bias -- attributing other peoples actions to their personalities while justifying your own as being dependent upon the situation in which you find yourself -- to the zero-sum bias, where situations are incorrectly perceived to be like, you guessed it, a zero-sum game in which the winner takes all, to even the IKEA effect, where people place disproportionately high values on things they partially assemble themselves.

Are they all legit? Gigerenzer, who has made himself into something of a bte noire among behavioral economists over the past couple decades, has his doubts. In his 2018 paper, he concluded that most studies on cognitive biases are flawed. They either rely on small sample sizes, misinterpret individual errors for systematic biases or underestimate how people absorb information based on how a fact or question is framed.

One oft-cited bias is the phenomenon of overconfidence. To the behavioral economist, business and finance are rife with examples of irrational decisions based on big heads and outsize egos. But what appears as a bias can often be perfectly deliberate and rational, Gigerenzer says.

For example, take an analyst who sells exchange rate or stock market forecasts. His predictions will invariably be mostly wrong -- because if they were right most of the time, he wouldnt have to work for a living. So the analyst, and others like him, tend to exude confidence because few would buy their advice if they were more honest about the accuracy of their calls.

Or how most people confidently believe Rome is south of New York, based on temperatures alone, even when its actually located further north. In isolation, it might seem like yet another example of overconfidence. But ask the same question comparing all big cities randomly rather than using a hand-picked pair and the bias disappears, according to Gigerenzer.

Behavioral economics claims overconfidence is a robust phenomenon, he said. Our research has shown that theres nothing robust about it. Theres a seduction to misrepresent reasonable behavior for biases.

Granted, Gigerenzers beef with behavioral economics, and its most influential proponents, like Kahneman, Amos Tversky and Richard H. Thaler, isnt new. If you google behavioral economics criticism, it doesnt take long before Gigerenzers name comes up, again and again. And he hasnt done himself any favors with his combative style. Even among his defenders, theres a sense that criticizing the discipline has become a bit of a hobbyhorse for Gigerenzer, and a slightly tiresome one at that.

Story continues

Kahneman, who was awarded the Nobel Prize in 2002, and Tversky long ago took issue with what they say is Gigerenzers willful misinterpretation of their positions and ideas, which misleads readers. Others, like Carnegie Mellons Alex Imas, say the problem is that Gigerenzer often uses oversimplified arguments to dismiss theories that he doesnt actually take head-on. For example, Gigerenzer once asserted behavioral economists had replaced Homo economicus with Homer Simpson as their model for human behavior.

For his part, Thaler, a Nobel laureate in his own right who runs an asset management firm when he isnt teaching behavioral science at the University of Chicago, suggested his own heuristic: ignore Gigerenzer.

Nevertheless, as behavioral economics becomes increasingly ubiquitous in everyday life, even proponents have started to acknowledge the potential pitfalls.

In a recent episode of Ted Seides Capital Allocators podcast, Albert Bridge Capitals Drew Dickson talked about how his team integrates behavioral economics into its investing approach. After listing some of the biases they watch out for, Dickson named the bias bias as his new favorite.

People are now talking about behavioral finance so much, and a lot of them are relatively new to it, they almost want to start looking as if theres definitely going to be a bias here, said Dickson, who declined to comment for this story. Youre biased to find a bias.

Gigerenzer isnt the only one looking to poke holes in behavioral economics.

Just this month, Nassim Nicholas Taleb, of The Black Swan fame, retweeted an earlier post highlighting an unfinished draft of his own takedown. Titled Nudge Sinister, How Behavioral Economics is Dangerous Verbalism, it summarizes 12 different errors that lead economists to produce or identify biases that arent really biases.

Ole Peters, a fellow at the London Mathematical Laboratory, has turned his attention to what he believes is an even bigger, more fundamental issue.

To oversimplify, he argues the entire field of economics is flawed because it doesnt correctly account for the problem of time, in what hes termed as the ergodicity problem. (If you want to get deep into the weeds, you can read his academic paper, published last month, here.) That results in discrepancies between how we would expect a rational actor to react to potential gains and losses, and our actual intuitions, a key consideration in the development of Kahneman and Tverskys prospect theory.

The upshot, according to Peters, is that in coming with psychological arguments about human behavior to patch up the discrepancy, behavioral economics mistakes a symptom of the problem for the problem itself.

Economics is firmly stuck in the wrong conceptual space, he wrote.

To contact the reporter on this story: Brandon Kochkodin in New York at bkochkodin@bloomberg.net

To contact the editors responsible for this story: David Papadopoulos at papadopoulos@bloomberg.net, Michael Tsang

For more articles like this, please visit us at bloomberg.com

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Calculated Surprise Leads to Groundbreaking Discovery in Cognitive Control Research – Newswise

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Newswise Humans control their behavior in numerous ways, from stopping the urge pick at a scab to resisting the impulse to eat an entire box of chocolates. Suppressing undesired behavior, referred to as cognitive control, traditionally has been linked to the functioning of the dorsal anterior cingulate cortex (dACC) in the front of the brain. Activity in dACC is observed across a variety of contexts, yet its function remains intensely debated in the field of cognitive neuroscience.

Theories of the role of dACC in inhibitory control highlight surprise, choice difficulty and value of control as key mechanisms. Although these theories have been successful in explaining dACC involvement in inhibitory control, it remains unclear whether these mechanisms generalize to motivated control. Motivated control processes help people achieve a desired goal even when doing so is difficult or costly.

A study led by a neuroscientist at Florida Atlantic University in collaboration with Radboud University, Nijmegen, the Netherlands, and Ghent University, Ghent, Belgium, sought to better understand how motivational control processes help maximize performance when faced with task challenges. Using functional magnetic resonance imaging (fMRI), researchers tested three prominent theories of cognitive control (predicted response outcome or PRO, expected value of control or EVC and choice difficulty or CD) using a speeded value-based decision-making task.

To differentiate among these theories, researchers developed a set of empirical predictions for what activation in the dACC should resemble if the theory was correct. By placing these theories in opposition within the same experiment, the researchers were able to develop a series of analyses to distinguish among the theories competing predictions.

Results of the study, published in the journal Nature Human Behavior, demonstrate how a singular model unifies conflicting findings on dACC function, takes cognitive control research to new heights, and provides fascinating insights into the role of dACC as a component of a network of brain regions that support motivated behavior.

Researchers discovered that the single mechanism of surprise defined in the paper as the difference between events that are expected to happen versus those that actually happen best accounts for activity in dACC during a task requiring motivated control. The series of analyses they performed indisputably supported the PRO model indicating that recognizing surprising events could provide a unified explanation for dACC function. Surprise signaling is the shared driver of inhibitory and motivated control and supports surprise coding as the core mechanism underlying medial prefrontal cortex function more generally, with the source of the surprise determining the exact neural population implicated.

During motivated control, we found that dACC activity reflects the calculation of surprise and does not track choice difficulty or value, said William Alexander, Ph.D., corresponding author and an assistant professor of psychology and a member of the Center for Complex Systems and Brain Sciences in FAUs Charles E. Schmidt College of Science. Instead, dACC activity is all about predictions of our choices and environment and especially signals when those predictions are wrong. A key contributor to motivated control, dACC tracks a computational quantity similar to surprise, which is generated when events differ from our expectations.

For the study, researchers dissociated the need to invigorate a response from reward incentive to distinguish motivated control from value-driven responding. fMRI data recorded human subjects performing various tasks ranging from easy to difficult. Participants within an fMRI experiment chose between two options each tied to a different amount of money and had to make choices very quickly, within a 750ms timeframe. This time pressure required them to exert cognitive control to balance the competing demands of the task, an assumption that was confirmed through their behavioral results.

Another key finding of the study is that several other regions of the brain in addition to the dACC also generated the patterns of activity predicted by the PRO model. Future studies will need to position dACC within a larger network of brain regions that collectively evaluate the need for increased control of behavior and then implement that control through changes in other systems.

Study co-authors are Eliana Vassena, Ph.D., Radboud University and Ghent University, and James Deraeve, Ghent University.

This research is supported by EC/EU Framework Programme for Research and Innovation, H2020/H2020 Priority Excellent Science, H2020 Marie Skodowska-Curie Actions (H2020 Excellent Science - Marie Skodowska-Curie Actions), and Fonds Wetenschappelijk Onderzoek (Research Foundation Flanders).

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About Florida Atlantic University: Florida Atlantic University, established in 1961, officially opened its doors in 1964 as the fifth public university in Florida. Today, the University, with an annual economic impact of $6.3 billion, serves more than 30,000 undergraduate and graduate students at sites throughout its six-county service region in southeast Florida. FAUs world-class teaching and research faculty serves students through 10 colleges: the Dorothy F. Schmidt College of Arts and Letters, the College of Business, the College for Design and Social Inquiry, the College of Education, the College of Engineering and Computer Science, the Graduate College, the Harriet L. Wilkes Honors College, the Charles E. Schmidt College of Medicine, the Christine E. Lynn College of Nursing and the Charles E. Schmidt College of Science. FAU is ranked as a High Research Activity institution by the Carnegie Foundation for the Advancement of Teaching. The University is placing special focus on the rapid development of critical areas that form the basis of its strategic plan: Healthy aging, biotech, coastal and marine issues, neuroscience, regenerative medicine, informatics, lifespan and the environment. These areas provide opportunities for faculty and students to build upon FAUs existing strengths in research and scholarship. For more information, visit fau.edu.

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Calculated Surprise Leads to Groundbreaking Discovery in Cognitive Control Research - Newswise