Monthly Archives: January 2020

Immunology

The babies ‘at risk of catching deadly illnesses’ in West Sussex – Spirit FM

The British Society for Immunology has urged the new government to deliver on its promise to develop the UKs first vaccine strategy to protect communities against nasty diseases.

Young children should get the so-called six-in-one jab, which protects against six serious infections including polio, whooping cough and diphtheria, in the first few months of their lives.

Public Health England data shows that 231 children in West Sussex who had their first birthday in the six months to September missed out on the vaccination.

But 94.8% of one year olds did have it, meaning the area was only just short of the 95% rate recommended by the World Health Organisation to prevent outbreaks.

The uptake rate for the South East over the period was 93.2%, while the figure across England stood at 92.1%.

Across England, the figure stood at 92.1%.

The British Society for Immunology said the uptake rate across England for the six-in-one vaccine among one year olds has averaged around 92% over the past year.

"Low levels of vaccination coverage matter as it means these diseases have the potential to spread within our communities, infecting unvaccinated people, with young babies and people with compromised immune systems particularly at risk.

"We urge the new government to deliver on its promise to develop the UKs first vaccine strategy and to fully fund immunisation services to ensure our communities are protected against these preventable diseases."

Dr Doug Brown, chief executive, The British Society for Immunology

But he also urged parents to make sure their children get the jabs.

"If you are worried your child hasnt received all the doses of the six-in-one vaccine, do make an appointment at your GP surgery.

"Its much better to get your child vaccinated than risk them catching one of these nasty diseases."

Babies should have three rounds of the six-in-one vaccination at eight, 12 and 16 weeks of age.

It helps them develop a strong immunity to diphtheria, hepatitis B, haemophilus influenza type b, polio, tetanus and whopping cough all described by the NHS as serious childhood diseases.

"Every child must be vaccinated against dangerous and potentially fatal diseases.

"Vaccine uptake is very high, at around 90%, for most childhood vaccines, but we are determined to drive rates up even further.

"Our new vaccination strategy, published in the new year, will consider a range of approaches to improve uptake."

Health minister, Nicola Blackwood

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The babies 'at risk of catching deadly illnesses' in West Sussex - Spirit FM

Immunology

Chemosensory Cells in the Nose Play a Role in Allergic Reactions – The Scientist

There are a lot of unknowns when it comes to understanding how the mammalian respiratory tract responds to allergens, but a study published today (January 17) in Science Immunology, offers new insight. Researchers identified a group of epithelial cells in the mouse nose that are capable of responding to allergens directly and also to ATP released in response to allergens. When exposed to allergens, these so-called brush cells secrete cysteinyl leukotrienes, proinflammatory lipids that have been previously shown to come mostly from immune cells and have been linked to asthma and allergies.

We have been interested in how allergens are recognized by the airway epithelium and how they drive immune responses that are biased towards allergic inflammation, says coauthor Lora Bankova of Harvard Medical School.

Previous research had shown that tuft cells, a solitary chemosensory cell type found in the intestine, are responsible for orchestrating immunity to parasitic worms in the gut, which trigger the same type of immune response as allergens. To determine whether there might be cells playing the same role in the airway epithelium, she and her colleagues investigated a similar cell type in the mouse trachea: brush cells. In work published in 2018, they analyzed the gene expression profile of brush cells and found that brush cell activation was important for airway inflammation.

In the trachea, brush cells are only about half of a percent of the total number of cells. These small numbers made it hard to do in vitro or ex vivo cultures in which it would be possible to directly stimulate them and see what happens, Bankova explains. So the research team looked for these cells elsewhere in the airway. In the current study they found that there are solitary chemosensory cells with similar transcriptional profiles to the tracheal brush cells present in much larger numbers in the mouse nose, where they contribute 48 percent of the total cells.

Because theyre so abundant we were actually able to isolate them and study them directly to see what activates them, what can they produce in response to stimulation, Bankova tells The Scientist.The researchers isolated nasal brush cells from mice and incubated them with ATP, which functions as a cellular stress or damage signal, or with allergens from dust mites or mold.

In response, the brush cells released proinflammatory cysteinyl leukotrienes at amounts comparable to or exceeding what immune cells produced when the research team stimulated them. Brush cell production of these lipids, and the lower levels generated by other cell types, indicate that the epithelial cells are likely the dominant source of cysteinyl leukotrienes in the nose. The researchers also showed that mice without brush cells had a reduced amount of allergic inflammation in response to an allergen.

Allergen activates them, and theyre important for generating the cysteinyl leukotrienes and allergic inflammation in that setting, says Bankova. She explains that its likely that theyre also responding to other sorts of damage in the airway epithelium because they release cysteinyl leukotrienes in response to ATP as well.

That ATP serves as a ligand for brush cells is the most surprising finding, says Christoph Schneider, a biologist at the University of Zurich who did not participate in the study. He adds that open questions include whether or not brush cells are the sole target of ATP and sole source of cysteinyl leukotrienes and whether this is true only for these airway brush cells or whether the same ATP effect is also observed in other situations, in other organs, et cetera.

To develop an asthma-like syndromeespecially if its allergic in natureyou have to have sensitization and then a subsequent response to challenge, so this is providing a mechanism by which the epithelium by itself is critical for sensitization, says Teal Hallstrand, a pulmonary physician at the University of Washington who was not involved in the work. Id be very excited to learn about whether or not people with asthma have an alteration in the number of these cells in their airways and what specific physiological effect that has.

S. Ualiyeva et al., Airway brush cells generate cysteinyl leukotrienes through the ATP sensor P2Y2, Science Immunology, doi:10.1126/sciimmunol.aax7224, 2020.

Abby Olena is a freelance journalist based in Alabama. Find her on Twitter@abbyolena.

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Chemosensory Cells in the Nose Play a Role in Allergic Reactions - The Scientist

Immunology

Emerging Biologic Treatments for Allergies and Asthma – Pulmonology Advisor

A great deal of research into allergic diseases has yielded many new observations that have immediate implications for treatment.1-3 Epidemiologic studies in several countries have indicated that the prevalence of allergies and asthma has been steadily increasing during the past 2 decades.2 At the same time, recent investigations have identified multiple pathogenic entities and several distinct allergic diseases with specific phenotypic characteristics and treatment response profiles, including allergic rhinitis, atopic dermatitis (AD), angioedema, and asthma.2

These findings have all contributed to a game-changing evolution in the treatment of allergic disease that is rapidly moving forward. In 2018, Dagmar Simon, MD, from Bern University Hospital, Switzerland, observed in the first of 2 annual reviews, With the development of novel therapies, of which some have already been approved, we face a new era of disease management and, with that, probably a modification of the expected course of diseases. 2

Targeting Immune Mechanisms for Therapy

Many large-scale studies have expanded the understanding of the important role of the immune system in homeostasis and host defense, which has led to the exploration of small molecule and biologic therapies that target immune mechanisms in allergic diseases. 1-3 The pathogenesis of allergies is determined by a complex of overlapping mechanisms that produce different patterns of inflammatory symptoms, as immune cells distributed throughout the body respond to individual and environmental triggers, mediated by lipids, growth factors, chemokines, cytokines, and endothelial barriers.

This multifaceted etiology of allergic diseases, including asthma, makes it difficult to identify a single target for therapy, so novel biological agents are designed to influence particular segments of the pathogenic pathways. Several types of immunologic therapies, including IgE and interleukin-4 (IL-4), IL-13, and IL-5 therapies that target eosinophils and alarmins, have already been approved, based on efficacy in clinical trials against specific subtypes of allergies.

Omalizumab is a monoclonal antibody with a high binding affinity for IgE that has demonstrated good efficacy against asthma and allergic conditions such as AD, reducing the frequency, severity, and chronicity of symptoms by inhibiting the T2 inflammatory action of IgE.3 Omalizumab is considered an appropriate add-on therapy for patients with uncontrolled allergic asthma, as well as those with chronic urticaria.

The IL-4 and IL-13 pathways have been implicated in the production of inflammatory eosinophils in allergic diseases; IL-4 cytokines contribute to IgE mechanisms and hepatic proliferation, whereas IL-13 has effects that are limited mostly to barrier dysfunction and biological disturbances of the skin.3 Dupilumab is a monoclonal antibody that works as a dual inhibitor of IL-4 and IL-13 signaling. It has been approved for the add-on treatment of uncontrolled eosinophilic asthma, AD, and chronic rhinosinusitis with nasal polyps.

Expression of eosinophils has a particularly strong association to asthma by contributing to inflammatory obstruction.4 The protein granules in eosinophils can also cause irritation to the airway structure and trigger bronchial spasm.4 Cytokines such as IL-5 produced by eosinophils may also stimulate new eosinophil formation to promote an ongoing cycle of airway dysfunction.4

Monoclonal antibodies (mAbs) that target the IL-5 pathway, including mepolizumab, reslizumab, and benralizumab, have demonstrated rapid reduction of eosinophil levels in patients with severe, uncontrolled asthma.3,4 All 3 drugs have been shown to reduce asthma exacerbations by about 50%.4 The challenges to IL-5 mAbs are that only about 50% of patients with severe asthma respond to these therapies, and the improvement in exacerbations may not be accompanied by improved lung function and quality of life.3 In addition, the benefits to IL-5 mAbs are lost with discontinuation of therapy, which may even produce rebound eosinophilia.3

Key mediators of homeostasis are cytokines such as thymic stromal lymphopoietin and IL-25 and IL-33, known as alarmins, as they initiate inflammation in response to damage or insult to the body. Tezepelumab is undergoing clinical trials as a first-in-class human mAb designed to block thymic stromal lymphopoietin, whereas antibodies to IL-33 and IL-25 are in the early stages of development. 3

Next Steps for Biologic Therapies

A multitude of dynamic internal and environmental factors have a continuing effect on the status of the immune system, eliminating the possibility of a single therapeutic target for many patients with resistant types of allergic diseases, particularly asthma. And although several biologic therapies have shown great promise, researchers are as-yet unable to identify the patients who are most likely to respond to these interventions. A 2020 review by Agache et al3 reported that achieving selective immune modulation without altering the healthy immune response and with a long-lasting disease modifying effect is still not reached. The immediate goals in biologic therapies for allergies and asthma are to develop biomarkers to identify patients who are most likely to respond to these therapies and to monitor disease severity. As experience with biological therapies continues to grow, they are expected move from their current position as add-on therapies for severe allergic disease to play a more prominent role in treatment strategies for many more allergy patients.

References

1. Simon D. Recent advances in clinical allergy and immunology 2019. Int Arch Allergy Immunol. 2019;180:291-305.

2. Simon D. Recent advances in clinical allergy and immunology. Int Arch Allergy Immunol. 2018;177:324-333.

3. Agache IO, Catalina C, Laculiceanu A, Rogozea L. Critical points on the use of biologicals in allergic diseases and asthma. Allergy Asthma Immunol Res. 2020;12:24-41.

4. Busse W. Biologic treatments for severe asthma: a major advance in asthma care. Allergol Int. 2019;68:158-166.

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Emerging Biologic Treatments for Allergies and Asthma - Pulmonology Advisor

Immunology

The Week Ahead: Abbott Laboratories and Johnson & Johnson Due – Morningstar.com

Earnings season continues next week with a medley of narrow- and wide-moat companies announcing earnings.

Johnson & Johnson (JNJ) and Abbott Laboratories (ABT) will both release earnings on Wednesday.

Johnson & Johnson has had steady growth for the past several years, and we expect this trend to continue with its fourth-quarter earnings. The company is expected to beat fourth-quarter earning estimates despite a recent onslaught of lawsuits. It is currently fighting over 16,000 asbestos-related lawsuits connected to its talcum powder products. Last October, Johnson & Johnson was also ordered to pay out $8 billion in a Risperdal (an anti-psychotic drug) product liability case.

Our director of equity analysis for North America, Damien Conover, stated that while we expect the quarters results to be under some pressure from patent losses in the firms oncology and immunology divisions, we expect the full-year 2019 earnings growth to be close to 6%. While patent pressures will likely continue into 2020, Johnson & Johnsons diversified platform should enable the firm to offset generic competition. Expected updates on the firms robotic device platforms should also help reinvigorate growth in the companys device segment. However, overall, from a valuation perspective, we view the company as slightly overvalued with some concerns on the firms late-stage pipeline weighing on our fair value estimate.

Abbott Laboratories is changing up its leadership this year with its senior vice president of finance and controller, Robert Funck Jr., becoming CFO and its president and operating chief, Robert Ford, becoming CEO this March. Miles White, the companys current CEO since 1999, will stay on as the executive chairman. Abbott Laboratories is currently waiting upon FDA approval for its new glucose monitor, Freestyle Libre 2.

Overall, the healthcare sector has increased 22% as of the end of 2019, which, while solid performance, underperformed the broader equity market performance of 31%. Concerns around potential healthcare policy change in the United States have increased uncertainty in the sector and have affected performance.According to Conover, although U.S. policy reform is probable, it is unlikely that a major overhaul will occur that will affect drug pricing power, which is expected to remain steady. Additionally, while the sector is slightly overvalued, with the most overvalued stocks in the device and diagnostics industries, there are some pockets of undervalued stocks in the drug and biotech industries.

On Tuesday, IBM (IBM), Netflix (NFLX), Capital One Financial (COF), UBS (UBS), Progressive (PGR), and TD Ameritrade (AMTD) will all be reporting earnings.

Thursday brings another round of earnings announcements, with Microsoft (MSFT), Procter & Gamble (PG), Intel (INTC), Comcast (CMCSA), and Discover Financial (DFS) reporting.

Microsoft has done well in recent months, earning a coveted $10 billion contract with the Joint Enterprise Defense Infrastructure Contract in October. The company has been focusing on the proliferation of its Azure platform and customer adoption of hybrid cloud environments on said platform.

In other economic news, Wednesday also brings with it the FHFA Housing Price Index for January, the Existing Home Sales report for December, and the EIA Crude Oil Inventories for Jan. 18.

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The Week Ahead: Abbott Laboratories and Johnson & Johnson Due - Morningstar.com

Biochemistry

Area students named to FHSU honor roll – News – The Ottawa Herald

By The Herald Staff

FridayJan17,2020at1:45PM

Area students are among the 1,596 students named to the 2019 fall Fort Hays State University Deans Honor Roll.

The Dean's Honor Roll includes undergraduate students only. To be eligible, students must have completed 12 or more credit hours and earned a minimum grade point average of 3.60 for the semester. Full-time on-campus and FHSU Virtual College students are eligible.

Students honored were:

Ottawa: Lia Irene Boese, senior, majoring in chemistry (biochemistry); Chloe Michal Brown, senior, majoring in organizational leadership; Marisa Sue Carman, senior, majoring in biology (cellular and molecular); Moriah Geschwentner, freshman, majoring in chemistry (biochemistry); Seth Benjamin Rossman, senior, majoring in agricultural business; Anthony David Strickling, senior, majoring in English (writing); Avery Lauren Welton, sophomore, majoring in biology (health professions).

Pomona: Cooper Aaron Flory, junior, majoring in agriculture (animal science).

Princeton: Jocelyn Nichole Woods, sophomore, majoring in radiologic technology.

Rantoul: Jacob Alexander Pryor, junior, majoring in technology studies (construction management).

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Area students named to FHSU honor roll - News - The Ottawa Herald

Biochemistry

New Trends of Biochemistry Analyzers Market with Worldwide Industry Analysis to 2030 – Fusion Science Academy

A thorough study of the competitive landscape of the global Rice Syrup Market has been given, presenting insights into the company profiles, financial status, recent developments, mergers and acquisitions, and the SWOT analysis. This research report will give a clear idea to readers about the overall market scenario to further decide on this market projects.

The report analysis the leading players of the global Rice Syrup market by inspecting their market share, recent developments, new product launches, partnerships, mergers, or acquisitions, and their target markets. This report also includes an exhaustive analysis of their product profiles to explore the products and applications their operations are concentrated on in the global Rice Syrup market. Additionally, the report gives two distinct market forecasts, one from the perspective of the producer and another from that of the consumer. It also offers valuable recommendations for new as well as established players of the global Rice Syrup market. It also provides beneficial insights for both new as well as established players of the global Rice Syrup market.

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Wuhu Deli FoodsAxiom FoodsWuhu Qinshi TangyeCalifornia Natural products (CNP)CargillADMABF Ingredients (ABFI)Shafi Gluco ChemBHARAT GLUCOSE PVTSINGSINO GROUP

Segment by RegionsNorth AmericaEuropeChinaJapanSoutheast AsiaIndia

Segment by TypeBrown RiceWhite RiceCertified Organic Rice

Segment by ApplicationConfectioneryProcessed FoodsDairy ProductsIce-creams

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Table of Contents

Report Overview: It includes six chapters, viz. research scope, major manufacturers covered, market segments by type, Rice Syrup market segments by application, study objectives, and years considered.

Global Growth Trends: There are three chapters included in this section, i.e. industry trends, the growth rate of key producers, and production analysis.

Rice Syrup Market Share by Manufacturer: Here, production, revenue, and price analysis by the manufacturer are included along with other chapters such as expansion plans and merger and acquisition, products offered by key manufacturers, and areas served and headquarters distribution.

Market Size by Type: It includes analysis of price, production value market share, and production market share by type.

Market Size by Application: This section includes Rice Syrup market consumption analysis by application.

Profiles of Manufacturers: Here, leading players of the global Rice Syrup market are studied based on sales area, key products, gross margin, revenue, price, and production.

Rice Syrup Market Value Chain and Sales Channel Analysis: It includes customer, distributor, Rice Syrup market value chain, and sales channel analysis.

Market Forecast Production Side: In this part of the report, the authors have focused on production and production value forecast, key producers forecast, and production and production value forecast by type.

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New Trends of Biochemistry Analyzers Market with Worldwide Industry Analysis to 2030 - Fusion Science Academy

Biochemistry

Love Aaj Kal Twitter Reactions: Looking in the adorable biochemistry of Karthik Aryan and Sara Ali Khan, the fans said & # 039; the movie will…

The trailer of Bollywood star Karthik Aaryan and Sara Ali Khan's film Love Aaj Kal was circulated because of the manufacturers today. Karthik and Sara's chemistry when you look at the truck associated with movie therefore the tip involving the two, Jhok followers are extremely much liked. Apart from Karthik and Sara, an innovative new face can also be noticed in this truck filled with love and psychological crisis.

->The title of the brand new face is Arushi Sharma and after seeing Arushi into the movie, the followers will also be desperate to find out about all of them. But before that, why dont we let you know that after viewing the trailer of 'Love Aaj Kal', the viewers has begun providing different responses on social networking. More followers have actually congratulated Karthik and Sara's love biochemistry on the movie 'Love Aaj Kal'. And additionally stated that the movie would turn out to be a blockbuster in the box-office.

In the film 'Love Aaj Kal', directed by Imtiaz Ali, the complete tale of exactly how love and wrangling between Karthik and Sara are placed on the major display screen from 1990 to 2020. How Karthik gets drawn to Sara from schooling time and starts to fall-in love involving the two while they develop youthful. By the way in which, the followers were also keen to understand pair of Karthik and Sara in the silver screen for a long period plus in view of the similarity, the manufacturers have actually established the truck today. After viewing the truck, Twitter is highly praised and it has additionally expressed its reaction. Let's see:

Receiving Sara ???

In trailer you can view exactly how event shes going to take this film . Kuddos to my woman. Gonna shine harder #SaraAliKhan#LoveAajKalhttps://t.co/m5BR3lfIqs

-? (@saraXstan_kiddo) January 17, 2020

I LOVEEE THE TRUCK !! BOMBBB ???? #LoveAajKal

-? (@anilasayshi) January 17, 2020

It's a Sara's program. It's her program. Her character is bomb. It's a really different personality from exactly what I've previously seen. Love her scenes when you look at the truck. Nailing it. ?I have actually alot to express about anything else but I'll hold it to myself. Positive vibes just.#LoveAajKal#SaraAliKhanhttps://t.co/QtD1gDa0JU

Ishita (@ ishita2301) January 17, 2020

Im enjoying the truck !! Omg something about Sara idk exactly what it really is. This girl could be the HEROINE. #LoveAajKal

Rima roentgen (@howudoin_r) January 17, 2020

No concealed definitions,Straight ahead story

Imtiaz Ali aag laga dega iss baar?#LoveAajKalpic.twitter.com/BeE4IjCihP

Kung Fu Fluffy (@That_FluffyGuy_) January 17, 2020

This love story will interact with childhood cool vibes im this film #LoveAajKal Going? will likely be awesome hit at box-office? ?????? https://t.co/F0xMTtdw3W

Deepak Rajgor? (@DeepakRajgor) January 17, 2020

Trailer of #LoveAajKal ???? This is likely to be an enjoyable movie. Imtiaz Ali is back My fav manager Kartik is impressive as well

Rakshith RK ?? (@RK_HUNTERR) January 17, 2020

Their chemistry ?????Littttttttttt ???? ? ? ? Babiesss ???????????????? #SaraAliKhan#KartikAaryan#LoveAajKalpic.twitter.com/sjRHbxBqku

-. (@crezy_virat_fan) January 17, 2020

Kartik Aaryan and Sara Ali Khan's film Love Aaj Kal are circulated in theaters on February 14. Randeep Hooda will additionally be noticed in a crucial role when you look at the movie.

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Love Aaj Kal Twitter Reactions: Looking in the adorable biochemistry of Karthik Aryan and Sara Ali Khan, the fans said & # 039; the movie will...

Biochemistry

Pillai named MHS October Youth Optimist of the Month – Merrillfotonews

The Optimist for the month of October, Aliyah Pillai, was nominated by Ms. Kerry Scholz.Ms. Scholz comments, Aliyah has been in my advisory for three years and was a student in my 9th grade Honors Physical Science class. Aliyah is one of the most optimistic, positive students I know. She is gifted not only with academic ability but also the attitude of a gracious servant. She is happy to help a student in need or even guide underclassmen on how to get involved in high school. She is very organized, hardworking, and never afraid to step up and help someone. Ms. Scholz also states, Aliyah is an exceptional student. As a senior, she has maintained a very high GPA while taking a rigorous class load of AP classes and college level English classes. In addition, she has made time for her love of music in Band and Choir. Beyond academics, she is also a varsity swimmer for MHS. Although she works hard in all her classes and never settles for less than her best, which is usually a 4.0, she always is one of my favorite people to see each day. She has a smile that is contagious and positive things to say to everyone around her. Aliyah truly deserves to be named Youth Optimist.Activities that Aliyah is involved in include MHS Swim Team (Captain), National Honors Society (Secretary), LINK Crew, MHS Wind Ensemble (1st Chair), Tri-M Music Honors Society (Vice President), LEAD Club, Marching Band, Musical Productions, Junior Optimist Club, MHS Concert Choir, Fellowship of Christian Athletes, and MHS Vocal Jayz.In our community, Aliyah is active with Make a Difference Day, Special Olympics, 30 Hour Famine, Red Shed volunteering, teaching and volunteering for swim, Jefferson Santas Workshop, Pep Band, volunteering at Church; including Mission trips to Florida, Texas, New York and Cambodia, Christmas Caroling, and giving out Valentines at nursing homes.Following graduation, Aliyah plans to attend UW LaCrosse to study biochemistry and criminal justice to eventually become a forensic chemist. Aliyah is the daughter of Susan and Keshav Pillai.

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Pillai named MHS October Youth Optimist of the Month - Merrillfotonews

Biochemistry

Obesity, heart disease, and diabetes may be communicable – UBC Faculty of Medicine

Brett Finlay

A new paper by UBC Faculty of Medicines Dr. Brett Finlay and a team of fellows from the Canadian Institute for Advanced Research (CIFAR) proposes that non-communicable diseases may be transmitted between people through the microbiome.

Non-communicable diseases, including heart disease, cancer, and lung disease account for 70 percent of deaths worldwide. These diseases are considered non-communicable because they are thought to be caused by a combination of genetic, lifestyle, and environmental factors and cant be transmitted between people.

The paper, published today in Science, throws this long-held belief into question by providing evidence that many diseases may be transmissible between people through microbes (including bacteria, fungi, and viruses) that live in and on our bodies.

If our hypothesis is proven correct, it will rewrite the entire book on public health, says Finlay, the papers lead author and a professor in the department of biochemistry and molecular biology and CIFAR fellow.

The authors base their hypothesis on connections between three distinct lines of evidence. First, they demonstrate that people with a wide range of conditions, from obesity and inflammatory bowel disease to type 2 diabetes and cardiovascular disease, have altered microbiomes. Next, they show that altered microbiomes, when taken from diseased people and put into animal models, cause disease. Finally, they provide evidence that the microbiome is naturally transmissible, for example: spouses who share a house have more similar microbiomes than twins who live separately.

When you put those facts together, it points to the idea that many traditionally non-communicable diseases may be communicable after all, says Finlay.

Brett Finlay

This paper provides a provocative new way to think about non-communicable diseases, with important implications for public health, says Alan Bernstein, the president and CEO of CIFAR. Ideas like this are a great example of what happens when top researchers from around the world work together in an environment of trust, transparency, and knowledge sharing.

While there is a lot of excitement about this hypothesis, the researchers are clear that much remains unknown about the mechanisms involved.

We hope the paper will inspire further research into the mechanisms and extent of communicability, says Finlay. We encourage researchers studying any disease to think about what effect microbes may be having.

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Obesity, heart disease, and diabetes may be communicable - UBC Faculty of Medicine

Biochemistry

Engineering Professor Graeve Inducted into Mexican Academy of Sciences – UC San Diego Health

University of California San Diego Mechanical and Aerospace Engineering Professor Olivia Graeve has been inducted into theAcademia Mexicana de Ciencias(Mexican Academy of Sciences or AMC). The AMC, established in 1959, is a non-profit non-governmental association of distinguished members of the Mexican scientific community. Its main objectives are to promote scientific development in Mexico, foster communication and collaboration with scholars in other countries, and provide unbiased scientific council.

Graeve, a Tijuana native and UC San Diego alumna, is one of only three corresponding members inducted in 2019. Corresponding members are researchers who reside outside of Mexico but have made significant contributions to the development of science in Mexico. Graeve is internationally recognized for her research on the development and manufacturing of nanomaterials for use in extreme conditions. Her Xtreme Materials Laboratory at UC San Diego discovers and characterizes materials for use in environments such as space, nuclear reactors, and biomedical devices.

It is a great honor to be included in the Academia Mexicana de Ciencias alongside so many phenomenal researchers, Graeve said. This recognition encourages me to continue working for the benefit of students on both sides of the U.S.-Mexico border.

In addition to her engineering research, Graeve is also the founder and co-director of the CaliBaja Center for Resilient Materials and Systems, which brings together researchers from UC San Diego and the Universidad Nacional Autnoma de Mxico (UNAM) to create materials and systems that can function at ultra-high temperatures, under extreme pressures and deformations, radiation, and other extreme conditions. The center develops materials for a wide range of applications, including defense, nuclear, pharmaceutical and aerospace.

Rafael Vazquez-Duhalt, co-director of the CaliBaja Center for Resilient Materials and Systems, professor at UNAM and the#1 most highly cited biotechnologist in Mexico, said Graeves induction into the AMC was reflective of both her scientific and binational outreach contributions.

The nomination of Dr. Graeve as corresponding member of the Mexican Academy of Sciences is a recognition of her fantastic and high-quality scientific work and her valuable and unique contribution to the Mexican-U.S. scientific and educational relationship, said Vazquez-Duhalt. Without doubt, the Mexican scientific community is enriched by the incorporation of Dr. Olivia Graeve into the Academia Mexicana de Ciencias.

In addition to her scientific accomplishments, Graeve has worked to use science and engineering as a bridge to unite the U.S. and Mexico. HerENLACE summer research program, entering its eighth year, brings more than a hundred high school and college students from both sides of the border to the UC San Diego campus each summer. Students work side by side with a partner from the other side of the border on cutting-edge research.

Science is universal, said Graeve. The intent of ENLACE is to have the students build human bridges across the border, using science and engineering as a tool to get them to engage, know each other and participate in the development of knowledge that will benefit humanity.

Graeve is also the faculty director of theIDEA Engineering Student Centerat the UC San Diego Jacobs School of Engineering, which works to foster an inclusive and welcoming community of engineering students and increase retention and graduation rates among all engineering students.

She is the second member of the UC San Diego faculty to be inducted into the AMC as a corresponding member. Mario Molina, distinguished professor of chemistry and biochemistry and a Nobel Prize recipient, is also a member of the AMC.

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Engineering Professor Graeve Inducted into Mexican Academy of Sciences - UC San Diego Health