New breakthrough discovery in immune system could treat all types of cancer – News Heads

New Delhi : A newly-discovered part of our immune system can be used to save and cure you from all types of cancers, say scientists.

A team of Cardiff University scientists discovered have discovered a method to kill prostate, breast, lung and other cancers in lab tests.

The findings from their study have been published in Nature Immunology. However, the procedure is yet to be tested on a patient, the scientists are positive and have a strong belief that this will turn in their favour.

Progress till date

Human body has its natural defence to the diseases, commonly known as immune system. The scientists were looking for "unconventional" and previously undiscovered ways the immune system naturally attacks tumours.

During the research, they found that T-cell inside human blood that keeps a check on the body to locate which part of the body has a threat to the disease and needs to be eliminated.

The difference is this one could attack a wide range of cancers.

"There's a chance here to treat every patient," researcher Prof Andrew Sewell told the BBC.

He added: "Previously nobody believed this could be possible.

"It raises the prospect of a 'one-size-fits-all' cancer treatment, a single type of T-cell that could be capable of destroying many different types of cancers across the population."

How does T-Cell work?

T-cells have "receptors" on their surface that allow them to "see" at a chemical level.

The Cardiff team discovered a T-cell and its receptor that could find and kill a wide range of cancerous cells in the lab including lung, skin, blood, colon, breast, bone, prostate, ovarian, kidney and cervical cancer cells.

Crucially, it left normal tissues untouched.

How would the treatment be done?

According to the scientists, a blood sample would be taken from the patient to locate T Cells then they will be genetically modified and placed back in the blood and then into the human body.

The new modified T cells will no locate the cancer-causing threats and would eliminate them automatically without causing any damage to other parts of our body.

Expert Researchers Reaction to the study

Lucia Mori and Gennaro De Libero, from the University of Basel in Switzerland, said the research had "great potential" but was at too early a stage to say it would work in all cancers.

"We are very excited about the immunological functions of this new T-cell population and the potential use of their TCRs in tumour cell therapy," they said.

Daniel Davis, a professor of immunology at the University of Manchester, said: "At the moment, this is very basic research and not close to actual medicines for patients.

"There is no question that it's a very exciting discovery, both for advancing our basic knowledge about the immune system and for the possibility of future new medicines."

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New breakthrough discovery in immune system could treat all types of cancer - News Heads

Kaitlin Walsh: Anatomy of the Senses, February 1 through 28 – River Cities Reader

Exhibit: Saturday, February 1, through Friday, February 28Opening Reception: Friday, February 7, 5:30 7:30 p.m.Berskin Gallery & Art Academy, 2967 State Street, Bettendorf IA

A celebration of the human body's most fascinating facets as viewed through abstract illustrations will grace the Berskin Gallery & Art Academy from February 1 through 28, with the Bettendorf venue hosting colorful, captivating works by Bettendorf artist Kaitlin Walsh in her new exhibition Anatomy of the Senses.

An independent artist specializing in abstract anatomy watercolor and oil paintings, Walsh, from a young age, exhibited an immense fascination with both art and science. She focused her studies on both disciplines, taking medical courses alongside fine art ones, and this culminated with a graduate degree in Biomedical Visualization at the University of Illinois at Chicago. Soon after graduation, Walsh married and had her first child, a son who spent several months in the hospital recovering from prenatal complications and an early birth. This experience motivated the artist to focus her career on her passion: portraying the beauty and complexity of the human body, as her sons initially precarious health status, while frightening, also compelled her to appreciate the things that were going well within his body.

Walsh was naturally impelled to convey this appreciation through her paintings, using the skills gained throughout her education. After spending some time honing her craft, increasing her inventory, and having more children, she opened up shop, saying, I feel incredibly lucky to have found success doing what I love. She is currently in the top 1 percent of Etsy sellers and has sold over 15,000 prints of her anatomical fine art paintings, and lives happily in Bettendorf with her husband and three healthy children. Kaitlin joined Berskin Gallery & Art Academy in December, says gallery owner Pat Berskin, adding, We are delighted to announce that she will begin teaching abstract watercolor in the spring. Her work is not only inspiring, but educational and aesthetically pleasing. Her positive energy and enthusiasm for the arts made for an excellent match with our programs.

A 5:30 p.m. opening reception will be held at the Berskin Gallery & Art Academy on February 7, and regular gallery hours are 11 a.m. to 6 p.m. on Wednesdays through Saturdays. Admission is free, and more information on the February 1 through 28 Kaitlin Walsh: Anatomy of the Senses exhibition is available by calling (563)508-4630 or visiting BereskinArtGallery.com.

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Kaitlin Walsh: Anatomy of the Senses, February 1 through 28 - River Cities Reader

Anatomy of a one-on-one steal: is this how we want the game to look? – NRL.COM

A rule tweak at the end of 2017 allowing one-on-one steals to be executed in multi-tackler tackles provided only one defender was involved at the time of the strip saw the tactic proliferate last season.

As we head into the third season of the new rule interpretation, NRL.com Stats has taken a look at how the practice has evolved, how it may evolve further and what implications that may hold.

After little change in 2018, the first year of the new interpretation, one-on-one strips proliferated in 2019.

The Raiders in particular and also the Storm got better at surprising teams by using secret code-words to co-ordinate for extra tacklers to drop off, leaving one man to effect a steal before the ball-carrier realised he was in danger of losing possession.

There were 120 successful steals through the 201 NRL matches in 2019. That is up from 68 in 2018 when the rule was first changed (the Raiders again were top with 11), and 44 in 2017 under the old rule.

The Raiders (28), Storm (19) and Warriors (11) were the only clubs to hit double digits in 2019. Josh Hodgson (14) individually effected more than 14 other clubs.

Teams were generally good at ensuring they didn't infringe once they decided to attempt a steal there were 25 penalties for stealing the ball where it was deemed there was more than one in the tackle.

There were a further 232 penalties for a stripping action however these are the ones where the ball pops free in a tackle and it is deemed a defender hit or raked at the ball so there is no deliberate stealing action.

For the most part the officials did a remarkably good job of deducing in a split second at what point the extra tacklers dropped off and at what point the ball came free.

With the practice likely to increase further in 2020 as teams aim to emulate the Raiders' success, things won't get easier for the officials.

The officials have to make the calls in real time (unless there is a rare instance of the steal directly leading to a try) so they do not have the benefit of video replays.

They didn't always get it right; for example frustrated Warriors coach Stephen Kearney lashed out after a couple of tight calls incorrectly went against his side in a 24-22 loss to the Eels in round 19. "If they can't get it right just piss it off," Kearney fired.

Roosters coach Trent Robinson and, perhaps surprisingly, Raider coach Ricky Stuart have publicly criticised the rule.

Robinson believes it is not in the spirit of the game and says his team will not be coached to do it (the Roosters registered just three steals in 2019) while Stuart suggested referees were being forced to guess when the extra tacklers drop off.

The reception has been largely positive from fans on both social media and in official fan surveys.

For the most part fans appreciated the unpredictability and the chance for momentum swings in a game where possession is at a premium and can be hard to claw back once the tide turns against a team.

The NRL's head of football elite competitions Graham Annesley touched on issues around the rule during his weekly briefings several times and, while admitting it placed extra pressure on referees, broadly supported the positive reception around the increase in unpredictability and renewed contest for possession.

One of the looming issues for the rule in 2020 is what actually constitutes "one-on-one". NRL.com Stats has isolated a number of incidents from 2019 where a ball-carrier was effectively gang-tackled, with defenders wrapping up his legs and non-ball-carrying arm while another defender started prising the ball out.

The extra defenders drop off with the steal largely effected already.

So while defenders of the new rule say "if you hang onto the ball you won't have a problem" that doesn't always hold true, as the attached examples highlight.

Some have expressed concern coaches may become so worried about having the ball ripped away, players would be instructed to wrap it up tightly in carries and put the offloads away. There has been no evidence of this yet but 2020 could be the acid test if more clubs work on the strategy.

NRL.com Stats has collated some examples that most clearly highlight the issue in the above video and still shots. Each was deemed a legal strip at the time, and resulted in the team executing the strip gaining possession.

These selected examples are at the more extreme end of a ball carrier being wrestled by one or more defenders while also being stripped by another. However, they do not represent the majority of instances of one-on-one strips.

In all, there were 120 steals in 2019, from 201 total games, at a rate of slightly over one steal for every two games.

Of those 120, some would have been legal one-on-one steals even under the old interpretation and in many more the stripping action largely occurs in a one-on-one scenario despite earlier involvement from an extra tackler or tacklers.

Less than a quarter which would equate to roughly one instance per round of eight games bears similarity to the attached examples.

So, at this stage, there is no epidemic of messy gang-tackle steals. However as we have seen with countless previous rules and interpretations, coaches are smart. Their concern is winning games. If they sense a chance to earn an advantage, they will explore it.

Will we see more cases like these examples in 2020? If so that would test the interpretation. If the above examples become more common that could have a detrimental effect on the game as a spectacle and raise questions about fairness.

How the Perth NRL Nines will work

The details are still being worked out but a challenge system will be in play in 2020.

A by-product of this is for the potential for steals to be adjudicated on by the Bunker with slow-motion replays rather than by on-ground officials on the fly.

If a captain believes his player has been unfairly stripped but play has been allowed to continue, he will be able to send that play to the Bunker.

This in turn could force some clarity around what happens in situations like those outlined above.

The reworded rule concerning stealing the ball is as follows:

a. The ball can be stolen from the player in possession at any stage prior to a tackle being complete when there is only one defender effecting the tackle;

b. If there are two or more defender[s] effecting the tackle and the ball is stolen a penalty should be awarded, except if the player in possession is attempting to ground the ball for a try.

So when it comes to a grey area where the ball is partway out while more than one player is still involved, it comes down to the referee's interpretation as so many other grey areas do.

Think forward passes that look backwards out of the hand but float forward, or when a player loses control in a play-the-ball while being crowded by a tackler. This is what could be tested by the Bunker this season.

The rule is certainly here to stay for 2020 at least the competition committee have already decided on rule changes for 2020 and the stripping law will stay as-is for at least this year.

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Anatomy of a one-on-one steal: is this how we want the game to look? - NRL.COM

Anatomy of an Ad: the story behind Greenpeace’s harrowing tale of turtle extinction – The Drum

Following the impact of its Rang-tan palm oil campaign, last week Aardman and Greenpeace unveiled 'Turtle Journey' - a heart-wrenching stop motion animation that worked to urge people to take action on the ocean crisis.

The campaign brought together the activist strength of Greenpeace with the famed creative of Aardman Animations, the makers of Wallace and Gromit and famous voices like Olivia Colman, Dame Helen Mirren and Stranger Things' David Harbour.

The Drum went behind the scenes to uncover how the major project came together.

A major focus for Greenpeace has been bringing the problems facing the worlds oceans as a result of climate change into public awareness. Back in 2018, what started as a Twitter joke, resulted in Stranger Things David Harbour dancing with penguins in the Antarctic to raise awareness of their plight.

That same year, Radiohead lead singer and environmental activist, Thom Yorke, released a single in support of Greenpeaces mission to protect the Antarctic Ocean from the effects of climate change, commercial fishing, and human interference. The ominous instrumental tracks message was relayed on Londons Marble Arch.

Meanwhile, to celebrate World Oceans Day in 2018, people from 25 countries and all seven continents painted themselves blue and perform human waves to show their support for ocean protection.

Happy World Oceans Day! Together, we're campaigning for an ocean rescue plan that'd create huge new ocean sanctuaries all over the world. If it...

But despite all the action Greenpeace has taken to drive this message home, Chris Till, deputy fundraising director at Greenpeace admitted its not been as effective as it would like.

"If you spoke to most people, they would have no idea that the United Nations (UN) is in the middle of negotiating a big new global ocean treaty, he said. Despite the fact that that could arguably affect the future of life on earth.

The Greenpeace team realised they needed to do something that would help it break out of its bubble of support, and get its message out into the wider world.

Ahead of the UN global ocean treaty talks in March, Greenpeace wanted to take plan to action by launching a petition to ensure the treaty came to life.

Greenpeace was also battling against peoples resistance to shocking footage. For decades, bodies like Comic Relief and Children in Need have relied on distressing footage to spur people into giving. But recent reports claim hearts are hardening against distressing content.

In preparing for this campaign, Greenpeace quickly came to the conclusion that emotional animations would be a more effective tactic.

As a society, were fast getting used to images that used to be shocking, admitted Till. Animation can be different as it allows people to emotionally connect. They can see themselves within the story in a way thats difficult to do in the real world.

The team had also learned a lesson from its wildly successful Rang-tan campaign; Greenpeaces emotional tale starring actress Emma Thompson that hit home the hard reality of palm oil, and the effect its cultivation has on the earth.

With help from Iceland, which chose to repurpose the video for its Christmas ad, the film thrust the issue of palm oil into the popular mindset. This, in turn, encouraged more people to consider it when buying food and products.

"It really pushed it into the public spotlight," explained Till. "And we knew we needed to do something similar with our next campaign, to get people really talking and taking action about the ocean crisis."

Fortuitously, around the time Greenpeace was mapping out this campaign Aardman Animation got in touch to say it was interested in working with the organisation.

It just felt like a perfect fit, Till said. We were looking for something that would make a strong connection with our audience and Aardman is brilliant at that. As we're both household names in our own right, it would help get the word out.

Following market testing around wider communication for the oceans issue, the research persuaded the team decided to focus on turtles. Till argued that while Greenpeace has a strong track record of talking about whales, they are received differently across the world. Turtles, on the other hand, have universal appeal.

The team at Greenpeace then spoke to Aardmans producers on what they wanted to get out of the film, the reaction they wanted and soon they began working on a brief.

This was then used to reach out to Aardmans network of directors, which garnered 12 pitches as to what this film could look like. They were brilliant and varied and offered many different ways of tackling what could be a very difficult subject, Till said.

We were clear that we wanted the animation to be immediately recognisable as Aardman, he explained on the creative vision Greenpeace had. We wanted something that would be immediately accessible and would take people on a real emotional journey.

Till explained that emotional punch was a phrase that continued to surface throughout their discussions as Greenpeace knew that while it was good at delivering facts and figures, its not always enough to make the case or make people prioritize the issue.

Till said deciding on the director was a fun if agonising decision process where the team refined and narrowed the ideas until they settled on Gavin Strange.

Just hearing Gav talk about his vision showed he really got to the heart of the issue, Till explained. He not only understood it intellectually, but he had a really strong emotional connection to the story." An added extra, to heighten his pitch, Strange read it alongside an accompanying musical mood real.

With the initial premise agreed back in mid-September, Aardman got going on the animation, while Greenpeace stayed in close contact throughout this time, during which Till admits the main producer was his main speed dial.

We had to get it right as its a big story to tell in not so long a video, he explained. Further, because of the process of stop-motion animation, it needed to sign off the script, set and characters before filming started, as once its set in clay, so to speak, all the changes become more difficult. If you go back and reanimate it loses you days and lots of effort.

Due to the nature of stop motion, the team used an animated storyboard, instead of a script. This was so they could work out the timings of each shot down to a fraction of a second.

One issue arose around how the characters should be depicted, as they needed to agree on the exact species of turtle to focus on - down to the colour of the shell. And this needed to balance with the story itself, to ensure that each character was scientifically accurate, with clear distinctions and personalities.

The team then had to work to a tight schedule, to ensure it was ready by January to give it enough airtime to make waves before the final found of the United Nations ocean treaty in March.

To help manage the team. who were working individually on shots, Aardman put boards on the walls with pictures of each shot so they could move between studios to show how it was working out.

All in all, the stop motion recording took six weeks - a painstaking process given the total length of the film is just under two minutes.

The famous voices involved include Olivia Colman, Dame Helen Mirren, and David Harbour, alongside Game of Thrones Bella Ramsey, Downton Abbeys Jim Carter, and comedian Ahir Shah.

Other than the scientific data and facts, Greenpeace also has an extensive phonebook of famous stars keen to support its campaigns.

Colman really did put everything into it, Till said on the Oscar-winning actress' performance. She took time off from doing the final takes of The Crown to rush over and deliver the recordings in under an hour. She just got it."

Till said he was in Harbours ear during his recording, as the actor was working remotely in New York. He said the whole process was interesting to experience, as each famous voice approached the shoot in a different way.

"We don't want to be accused of being hyperbolic," claimed Till on why alongside the video, it has produced a report about the threats that are facing turtles in the real world. "We know it's crucial for us as a lobbying and scientific campaigning organisation we need to demonstrate that science is there to back this story up."

'Turtles Under Threat' reports that while the creature has traversed the world's oceans for more than 100 million years, now six in seven marine turtles are on the red list of the International Union for Conservation of Nature and are threatened with extinction.

"Unfortunately, our film might be fiction, but what happens to our turtle family in that film is sadly happening to real turtles all over the world," Till said dejectedly.

With the campaign launching last week, its still early days. But Greenpeace said it has already collected over 280,000 signatures - not far off its 300,000 target.

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Anatomy of an Ad: the story behind Greenpeace's harrowing tale of turtle extinction - The Drum

‘Grey’s Anatomy’: Will Alex’s Exit Be Addressed When Season 16 Returns for the Winter Premiere? – Showbiz Cheat Sheet

To put it simply, Greys Anatomy wont be the same without Alex Karev (Justin Chambers). In January, the 49-year-old actor announced his departure from the Shondaland series after 16 seasons. And reportedly, fans have already seen Chambers final moments as Alex in the 350th episode milestone. But without a proper sendoff before the midseason hiatus, will Alexs exit be addressed in the Greys Anatomy Season 16 winter premiere? Heres what we know so far.

On Jan. 10, Chambers released a statement about his departure from Greys Anatomy, thanking everyone from his immediate family to the cast and crew of the ABC series.

Theres no good time to say goodbye to a show and character thats defined so much of my life for the past 15 years, Chambers said, per Deadline. For some time now, however, I have hoped to diversify my acting roles and career choices. And, as I turn 50 and am blessed with my remarkable, supportive wife and five wonderful children, now is that time.

He continued: As I move on from Greys Anatomy, I want to thank the ABC family, Shonda Rimes, original cast members Ellen Pompeo, Chandra Wilson and James Pickens, and the rest of the amazing cast and crew, both past and present, and, of course, the fans for an extraordinary ride.

Then when speaking with Page Six, Chambers revealed it was difficult leaving the show. Anywhere that you spend 15 years, its a big chunk of your life, Chambers said. Greyshas been very supportive of me and Im very grateful and its been a great ride.

[Spoiler alert:reys AnatomySeason 16 midseason premiere.]

Following the news, multiple outlets confirmed Chambers previously filmed his final Greys Anatomy episode the 350th episode aired on Nov. 14. Alex last appeared to support Meredith Grey (Ellen Pompeo) during her medical license hearing. He brought in previous patients and read heartfelt letters written by old co-workers. However, Alex did not show up in the midseason finale. Instead, he went home to take care of his mom in Iowa offscreen.

Naturally, Greys Anatomy fans are now curious to see how the ABC drama writes Alex out of the story. Of course, most individuals are worried the team will kill the character off, given the seemingly sudden departure. And others are concerned Chambers exit wont be addressed at all.

Nevertheless, TVLine confirmed the winter premiere on Jan. 23 will address Chambers absence. But fans might be a little disappointed, as the publication hinted it will not be in a way that will bring closure to the matter.

No matter how the Greys Anatomy team addresses Chambers exit, fans can still expect a dramatic winter premiere. When a fan asked TVLine whether they should expect tears during the episode, the publication couldnt reveal any major plot points or if someone dies. But the crossover event with Station 19 will certainly pack a punch.

There will be a major turning point for one couple and a big decision thats sure to haunt the doctor who makes it. Meanwhile, an emotional scene will emerge during the Station 19 Season 3 premiere. And it looks like Teddy (Kim Raver) will share a special moment with Ben (Jason George) at some point.

Then in an interview with People, Jesse Williams promised the Greys AnatomyStation 19 crossover will be scary as hell and startling.

And Station 19s Barrett Doss confirmed. The season premiere, everybody is in it together, she said. The stakes are super high and they all have to use all of their skills to solve this problem.

Read more:Greys Anatomy: These Jo and Alex Theories Explain What Happens to the Karevs After Justin Chambers Leaves

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'Grey's Anatomy': Will Alex's Exit Be Addressed When Season 16 Returns for the Winter Premiere? - Showbiz Cheat Sheet

We ranked the most popular Grey’s Anatomy actors by salary – gotech daily

Greys Anatomy is the longest running medical drama on television that premiered in 2005 and is currently airing its 16th season. The show revolves around the protagonist Meredith Gray and her experience as a surgeon at the Gray Sloan Memorial Hospital in Seattle.

The show has seen quite a turn in actors over the past fifteen years. The characters of Meredith Gray, Alex Karev, Miranda Bailey and Richard Webber are the only actors who have appeared in all sixteen seasons. No heartbreak, but Alex Karev is also going. Season 16 will be his last on the Shonda Rhimes hit show.

Ellen Pompeo, who plays Meredith Gray, earns over $ 575,000 per episode. With an annual income of nearly $ 20 million, she is by far the highest paid actress on the show.

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Isaiah Washington had a rather dishonorable exit from Greys Anatomy. At the end of the third season, he was released because of the other actor T.R. Knight. The creator Shonda Rhimes declined to take him back, even after he made a public apology. He played Dr. Preston and Burke has a net worth of approximately $ 500,000.

via ET Online

Camilla Luddington appeared for the first time in season 9 as a recurring cast member and became a regular in season 10. She plays Jo Karev, the wife of Alex Karev. In real life, British actress Camilla Luddington is married to actor Matthew Alan and has assets of around $ 1.3 million.

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Kevin McKidd plays Dr. Owen Hunt and has been an integral part of the cast since the fifth season of the series. He has touched millions of viewers with his portrayal of a soldier suffering from PTSD. Before he got a role in the series, he was best known for playing the character Tommy in Trainspotting. His net worth is around $ 2 million.

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Sarah Drew played the role of Dr. April Kepner, who was featured for the first time in season 6 as a recurring actor, and from season 7 until her departure in season 14. Before joining the cast, she played the role of Hannah in Everwood from 2004 to 2006. Her net worth is $ 3 million.

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Martin Henderson most recently appeared in the original Netflix series Virgin River, but is also a Greys Anatomy alum! He played Dr. Nathan Riggs, the fianc of Megan Hunt, Owen Hunts sister. Although his character only appeared in seasons 12-14, he left a lasting impression on the fans. He has a fortune of $ 6 million.

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Eric Dane played the role of Dr. Mark Sloan, also known as McSteamy, from season 2 to 9 in the series. He started his career as a guest star in Gray and became a regular actor in season three. He is a respected actor with a net worth of over $ 7 million.

via IMDB

James Pickens Jr. is one of the original actors who appeared in every season of the show. As Dr. Richard Webber, he was the longstanding chief of surgery until his successor, Dr. Derek Shepherd takes over in season two. The estimated actor has a fortune of $ 10 million.

via Entertainment Weekly

Chandra Wilson is one of the best known actresses from Greys Anatomy and plays the role of Dr. Miranda Bailey. She has been a regular cast member throughout the series, and there are no discussions that shell be leaving soon! Her net worth is approximately $ 10 million.

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Jesse Williams plays one of the most popular doctors on the set, Dr. Jackson Avery. He was in season 6 for the first time as a recurring actor on the set and in season 7 regular guest. He signed up for season 17 so we dont lose any more favorites! His net worth is $ 12 million.

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Justin Chambers plays the revered Dr. Alex Karev, a character who has grown from a childhood visit to the interim director of the Gray Sloan Memorial Hospital. Although he retires after 15 years with the show, he leaves a legacy and enthusiastic fans. He said that after a long show, he wanted to spend more time with his wife and five children. His net worth is $ 18 million.

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Kate Walsh played Addison Montgomery, the ex-wife of Derek Shepherd. She appeared several times in the first seasons and was the main actress of the spin-off show Private Practice. She hasnt appeared on the series since season 8, but who knows what the future might look like? Her net worth is $ 20 million.

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Sandra Oh played the role of Dr. Cristina Yang, Meredith Grays best friend and ally. Her farewell to the show at the end of season 10 shocked and saddened the fans. Although she had a great run, she wanted to explore different roles and opportunities in acting. Her net worth is $ 25 million.

via Today Show

There has been much speculation that the reason for Katherine Heigls departure from the show was her bad attitude and inability to work well with her co-stars. Although not confirmed, Heigl, the Dr. Izzie Stevens played, a history of bed behavior on set. Still, she is a very talented and successful actress with a net worth of $ 30 million.

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Patrick Dempsey played the icon of Dr. Derek Shepherd until his tragic death on screen in season 11. As Merediths husband, partner and greatest cheerleader, his departure caused a stir in the script and changed Meredith forever. He continues to trade and spend more time with his family and car collection. He has a net worth of $ 60 million.

via Vanity Fair

Ellen Pompeo is the highest paid actress at Greys Anatomy, and rightly so. She was a constant throughout the series, and her role is an integral part of the plot. With a salary of approximately $ 575,000 per episode, she earns a good salary! Her net worth is $ 70 million.

Next20 surprising things about Matthew Perrys time with friends

About the author

Ariane Signer has been writing her thoughts, fears and dreams in magazines since the early 90s. As a personal development and self-help junkie, she has been working as a freelance writer since 2016. The Canadian-born found her home in the small town of Switzerland, where she lives with her husband and two young sons.She is the author of Things That Shine: Poems

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We ranked the most popular Grey's Anatomy actors by salary - gotech daily

Greys Anatomy: Fans Argue Over a Controversial Possible Ending to the Show – Sahiwal Tv

With the departure of yet one more fan-favorite character, viewers are discussing once more what they wish to see when Greys Anatomy lastlyinvolves an in depth. While we dont know the way or whenEllen Pompeo,Shonda Rhimes, andKrista Vernoffplan to finish the present, what we do know is what number of followers would hate to see it occur.

When the collection went onwinter breakin late November, we left off with Jo Wilson (Camilla Luddington) trying to undertake a Safe Haven child who was dropped off at Station 19. However, her husband, Alex Karev (Justin Chambers), didnt make an look on the midseason finale episode.

On Friday, Jan. 10, 2020, Chambers introduced he was leaving the present, which is now in its 16th season. His departure is what spawned the extreme discuss concerning the present ending.

Theres no good time to say goodbye to a show and character thats defined so much of my life for the past 15 years, Chambers assertion to USA Today learn.

Chambers cited his purpose for leaving as desirous to tackle new and totally different roles in his profession.

For some time now, however, I have hoped to diversify my acting roles and career choices. And, as I turn 50 and am blessed with my remarkable, supportive wife and five wonderful children, now is that time, the assertion continued.

With his departure, the present will now be all the way down to solely three unique solid members; Pompeo, James Pickens, Jr. and Chandra Wilson.

Greys Anatomy ought to finish quickly and it ought to finish with Meredith sitting in a house and a fairly black lady is sitting along with her speaking to her and Meredith is like Are you the doctor? And Zola is like No mom, but I am a doctor

JRS (@catsandteas) January 13, 2020

Greys Anatomy should end soon, and it should end with Meredith sitting in a home, and a pretty black woman is sitting with her talking to her, and Meredith is like Are you the doctor? And Zola is like No mom, but I am a doctor, wrote the fan.

Then Merediths like I think I was a doctor once, continued the Twitter person. And Zola hands her a ton of notebooks which she starts to read and its her journals from when she was a doctor before she got Alzheimers, and all of the writings are the monologues she says in every episodes beginning.

The unique tweet obtained 124,700 likes and 16,900 retweets. Many followers agreed that they wish to see the present finish with Meredith additionally getting Alzheimers illness, like her mom. However, a superb quantity of followers had been additionally appalled on the thought of Dr. Grey ending up like that.

So many Greys followers need it to finish this manner, and Id be sooooo pissed if it did,wrote one Twitter userin disagreement. After EVERYTHING they put her through, giving her Alzheimers would just be wrong. I get that it makes perfect sense for the storyline, but still. Let her be happy for once.

Although many followers appreciated the unique tweet, some really feel that it will be terrible so as to add yet one more tragic factor to Merediths life.

Nope, absolutely not, added one other fan. If they end her story with Alzheimers, I will scream.

Many customers on Reddit additionally agree that they are not looking for the present to finish this manner.

That would be the most predictable ending at this point, wrote one otherviewer on Reddit.

Several Redditors commented on the identical factor. If Meredith has Alzheimers, it will be extraordinarily predictable. Although most followers consider its time for the present to finish, nobody is in settlement on the way it may finish.

It appears like solely Pompeo, Rhimes and Vernoff know the reply to that one. You can catch the midseason premiere of Greys Anatomy Thursday, Jan. 23, 2020, at 9 p.m. ET.

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Greys Anatomy: Fans Argue Over a Controversial Possible Ending to the Show - Sahiwal Tv

‘Walking Sharks’ Are a Thing, But Don’t Worry – They’re Adorable – ScienceAlert

In an epic 12-year research effort, an international team of scientists has discovered four species of 'walking sharks', almost doubling the known species count of these rare and gifted animals.

While the image of a shark chasing you onto a sandy beach may now be firmly planted in your mind, that's not how the physiology of these animals works and there's nothing to fear from these species found in tropical waters between northern Australia and New Guinea (unless you're a tiny marine animal, that is).

"At less than a metre [3.3 ft] long on average, walking sharks present no threat to people,"says biologist Christine Dudgeonfrom the University of Queensland in Australia.

"But their ability to withstand low-oxygen environments and walk on their fins gives them a remarkable edge over their prey of small crustaceans and molluscs."

The four new shark species belong to the genus Hemiscyllium. The new members of the group were linked to five existing kinds of shark through genetic analyses, using tissue samples from live-caught specimens found during the study.

"We estimated the connection between the species based on comparisons between their mitochondrial DNA which is passed down through the maternal lineage," Dudgeon says.

"This DNA codes for the mitochondria, which are the parts of cells that transform oxygen and nutrients from food into energy for cells."

The results confirmed the new animals' DNA was consistent with existing Hemiscyllium species, which can be traced back to the Late Cretaceous period, extending from roughly 66 to 100 million years ago.

Given the immense time scales involved, and the broad scope of international waters, it can be difficult to know exactly how these walking shark species came to be, and why they evolved their separate adaptations.

"It can be challenging to identify the forces that drive speciation in marine environments for organisms that are capable of widespread dispersal because their contemporary distributions often belie the historical processes that were responsible for their initial diversification," the authors explain in their paper.

Nonetheless, we can speculate. In this instance, the researchers suggest Hemiscyllium may have effectively hitch-hiked around the place while geographical shifts emerged over aeons, as tectonic activity and sea-level changes shifted the positions of reefs and island chains.

"Data suggests the new species evolved after the sharks moved away from their original population, became genetically isolated in new areas and developed into new species," Dudgeon says.

"They may have moved by swimming or walking on their fins, but it's also possible they 'hitched' a ride on reefs moving westward across the top of New Guinea, about 2 million years ago."

The team says more walking shark species are likely to exist, too it's just a matter of finding them.

The findings are reported in Marine and Freshwater Research.

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'Walking Sharks' Are a Thing, But Don't Worry - They're Adorable - ScienceAlert

Our bodies are chronically in "threat mode" – being kind recalibrates our nervous system – Big Think

Kindness is a virtue that is admired and applauded, in most cases. But did you know that being kind can also be good for your health? In fact, being compassionate to others can actually reset our consistently stressed-systems back into our default "rest mode", causing all kinds of positive effects to our overall health.

Living in "threat mode" isn't healthy for our minds or our bodies.

Image by Pogorelova Olga on Shutterstock

According to Dr. James Doty, Stanford professor and author of Into the Magic Shop: A Neurosurgeon's Quest to Discover the Mysteries of the Brain and Secrets of the Heart, the nervous system was never made to be in threat mode all the time. And yet, our adrenaline-fueled, "on-the-go" lifestyles have us operating mainly in "threat mode", and this can actually be one of the reasons we contract a variety of different illnesses.

Our bodies release inflammatory proteins in response to stress. Because of this release, our nervous system shows a decrease in the capabilities of our immune system, which is what responds to threats such as germs or bacteria that cause illnesses.

The constant over-stimulation of our nervous systems caused by our fast-paced way of living also makes us much more inclined to jump to (often judgmental) conclusions about other people.This kind of quick judgment actually dulls our own ability to act out of compassion for others. Which, in turn, leaves us operating in a constant "threat mode", which has negative long-term effects on our health.

The ability to feel and act out of compassion for others can have a huge effect on your overall health.

Dr. Doty explains it best in this Uplift article:

"When someone acts with compassionate intentions, this has a huge, huge positive effect on their physiology. It takes them out of threat mode and puts them into the rest and digest mode. What happens when that occurs is it changes how they respond to events."

According to Dr. Doty, instead of a quick response that is often based on fear, anxiety or stress, our response time is slower and offers a more deliberate response that tends to be more effective, more creative and more compassionate. We are able to change the response we have to events because we are allowing the executive control area of our brain to function at the highest level.

Several studies at Emory University have demonstrated this and given results that support the idea that regular compassionate acts or compassion-based meditation practices can reduce negative neuroendocrine interactions in our brains (which are the interactions between our nervous system and the endocrine system).

The benefits from being kind can help us live healthier, happier lives.

Photo by ESB Professional on Shutterstock

When we switch to our parasympathetic nervous system (which we instinctively do, when we act out of compassion), we flip out of the sympathetic nervous system that most of us live in due to our busy lifestyles.

When this switch happens, our heart rate variability increases, which causes a boost in our immune system. This immune system boost can help us fight off infections or illnesses.

Now, let's talk about telomeres.

"Telomeres" likely isn't a word you've heard before, so let me give a quick definition of what they are to us.

Telomeres are like little caps that protect the ends of chromosomes and genetic information in our bodies during cell division. Essentially, telomeres get shorter each time a cell copies itself (which happens constantly).

Eventually, telomeres get too short to do their job of protecting the cells, and this causes the cells to age and eventually stop functioning properly. This is how telomeres essentially act as an aging clock in every cell we have.

Research by Dr. Doty has shown that one of the long-term positive effects of living in our parasympathetic nervous system (referred to as our "resting" mode) is that our telomeres actually increase in length.

In theory, over time, being kind and compassionate can actually slow down the aging process in some of the cells of our body. How crazy is that!?

Just as showing compassion can recalibrate our systems, experiencing compassion or kindness from others also has a positive impact on our systems. Research by a Stony Brook University professor (Stephanie Brown) has proven that experiencing compassion can lead to tremendous improvements in our mental and physical well-being, as well.

This ground-breaking research allow us to understand the benefits that kind human interactions can have on the health of our minds and bodies.

The positive ripple effect that comes from being kind doesn't just impact our health, but it can impact our interactions with others and set off a positive chain reaction we can't even begin to understand. Resetting your own system into its natural resting mode by taking ourselves out of threat mode can allow us to process things more clearly and make better choices.

In a world where you can be pretty much anything - be kind...it's good for your health.

See more here:
Our bodies are chronically in "threat mode" - being kind recalibrates our nervous system - Big Think

Effects of Wearing Compression Stockings on Exercise Performance and A | OAJSM – Dove Medical Press

Gustavo R Mota,1 Mrio Antnio de Moura Simim,2 Izabela Aparecida dos Santos,1 Jeffer Eidi Sasaki,1 Moacir Marocolo3

1Human Performance and Sport Research Group, Department of Sport Sciences, Institute of Health Sciences, Federal University of Triangulo Mineiro, Uberaba, MG, Brazil; 2Research Group in Biodynamic Human Movement, Institute of Physical Education and Sports, Federal University of Cear, Fortaleza, CE, Brazil; 3Physiology and Human Performance Research Group, Department of Physiology, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil

Correspondence: Gustavo R MotaHuman Performance and Sport Research Group, Department of Sport Sciences/Institute of Health Sciences, Federal University of Tringulo Mineiro, Av. Tutunas, 490 Uberaba/MG, Uberaba 38061-500, BrazilTel +55 34 3700-6633Email grmotta@gmail.com

Abstract: This systematic review investigated the effects of wearing below-knee compression stockings (CS) on exercise performance (or sports activity) and associated physiological and perceived indicators. We searched articles on PubMed using the following terms: graduated compression stockings; compression stockings; graduated compression socks; compression socks combined with performance, athletes, exercise, exercise performance, fatigue, sports and recovery, resulting in 1067 papers. After checking for inclusion criteria (e.g., original studies, healthy subjects, performance analysis), 21 studies were selected and analyzed. We conclude that wearing CS during exercise improved performance in a small number of studies. However, wearing CS could benefit muscle function indicators and perceived muscle soreness during the recovery period. Future research should investigate the chronic effect of CS on Sports Medicine and athletic performance.

Keywords: ergogenic aid, fatigue, sports, medicine, prevention, soccer, running

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

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Effects of Wearing Compression Stockings on Exercise Performance and A | OAJSM - Dove Medical Press